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caffeine and Abnormalities, Congenital

caffeine has been researched along with Abnormalities, Congenital in 22 studies

Research Excerpts

ExcerptRelevanceReference
"A risk analysis of in utero caffeine exposure is presented utilizing epidemiological studies and animal studies dealing with congenital malformation, pregnancy loss, and weight reduction."4.87Evaluation of the reproductive and developmental risks of caffeine. ( Brent, RL; Christian, MS; Diener, RM, 2011)
"8 for total maternal dietary caffeine intake or specific types of caffeinated beverages and anotia/microtia, esophageal atresia, small intestinal atresia, and craniosynostosis; however, dose-response patterns were absent."3.77Maternal caffeine intake and risk of selected birth defects in the National Birth Defects Prevention Study. ( Browne, ML; Druschel, CM; Feldkamp, ML; Hoyt, AT; Marshall, EG; Rasmussen, SA; Romitti, PA, 2011)
"Among all the birth defects, maternal caffeine consumption was associated with a higher risk of cardiovascular defects, [odds ratio (OR) 1."2.72Maternal intake of caffeinated products and birth defects: a systematic review and meta-analysis of observational studies. ( Li, W; Luo, L; Mu, D; Qiu, X; Qu, Y; Shi, J; Tang, J; Wang, H; Xia, B; Xiong, T; Yue, Y; Zeng, Y, 2021)
"Caffeine is a methylated xanthine that acts as a mild central nervous system stimulant."2.41Teratogen update: evaluation of the reproductive and developmental risks of caffeine. ( Brent, RL; Christian, MS, 2001)
"Although an association between malignant hyperthermia (MH) and congenital abnormalities has been recorded, no prospective study has been attempted to investigate this relationship."1.28An association between certain congenital abnormalities and the malignant hyperthermia trait. ( Gericke, GS; Isaacs, H, 1990)
"Caffeine at high doses is a known rodent teratogen and induces limb malformations along with cleft palate in various strains of rats and mice."1.27Prevention of caffeine-induced limb malformations by maternal adrenalectomy. ( Moriguchi, M; Scott, WJ, 1986)

Research

Studies (22)

TimeframeStudies, this research(%)All Research%
pre-199011 (50.00)18.7374
1990's2 (9.09)18.2507
2000's6 (27.27)29.6817
2010's2 (9.09)24.3611
2020's1 (4.55)2.80

Authors

AuthorsStudies
Yue, Y1
Li, W1
Tang, J1
Zeng, Y1
Xiong, T1
Qiu, X1
Shi, J1
Wang, H1
Xia, B1
Luo, L1
Qu, Y1
Mu, D1
Browne, ML2
Hoyt, AT1
Feldkamp, ML1
Rasmussen, SA1
Marshall, EG1
Druschel, CM1
Romitti, PA1
Brent, RL2
Christian, MS2
Diener, RM1
TANNERT, S1
SZEKERES, L1
BANHIDY, F1
LENARD, G1
SOTI, J1
NISHIMURA, H1
NAKAI, K2
Reece, EA1
Renwick, JH1
Kelsey, FO1
Colomina, MT1
Sanchez, DJ1
Esparza, JL1
Domingo, JL1
Burdan, F1
Furneaux, EC1
Langley-Evans, AJ1
Langley-Evans, SC1
Nomura, T1
Gericke, GS1
Isaacs, H1
Moriguchi, M1
Scott, WJ1
Pieters, JJ1

Reviews

6 reviews available for caffeine and Abnormalities, Congenital

ArticleYear
Maternal intake of caffeinated products and birth defects: a systematic review and meta-analysis of observational studies.
    Critical reviews in food science and nutrition, 2021, Volume: 61, Issue:22

    Topics: Abnormalities, Drug-Induced; Caffeine; Congenital Abnormalities; Female; Humans; Odds Ratio

2021
Evaluation of the reproductive and developmental risks of caffeine.
    Birth defects research. Part B, Developmental and reproductive toxicology, 2011, Volume: 92, Issue:2

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Caffeine; Congenital Abnormalities; Fem

2011
Maternal exposure to caffeine and risk of congenital anomalies: a systematic review.
    Epidemiology (Cambridge, Mass.), 2006, Volume: 17, Issue:3

    Topics: Adolescent; Adult; Caffeine; Congenital Abnormalities; Female; Humans; Pregnancy; Risk Assessment; T

2006
[Teratology, 40 years after the thalidomide tragedy].
    Ginekologia polska, 2001, Volume: 72, Issue:2

    Topics: Abnormalities, Drug-Induced; Abnormalities, Radiation-Induced; Abortion, Spontaneous; Animals; Caffe

2001
Teratogen update: evaluation of the reproductive and developmental risks of caffeine.
    Teratology, 2001, Volume: 64, Issue:1

    Topics: Abortion, Spontaneous; Animals; Animals, Newborn; Behavior; Caffeine; Central Nervous System; Coffee

2001
Nausea and vomiting of pregnancy: endocrine basis and contribution to pregnancy outcome.
    Obstetrical & gynecological survey, 2001, Volume: 56, Issue:12

    Topics: Abortion, Spontaneous; Alcohol Drinking; Caffeine; Chorionic Gonadotropin; Congenital Abnormalities;

2001

Trials

1 trial available for caffeine and Abnormalities, Congenital

ArticleYear
Regulatory aspects of teratology: role of the Food and Drug Administration.
    Teratology, 1982, Volume: 25, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Clinical Trials as Topic; Congenital Abnormalities;

1982

Other Studies

15 other studies available for caffeine and Abnormalities, Congenital

ArticleYear
Maternal caffeine intake and risk of selected birth defects in the National Birth Defects Prevention Study.
    Birth defects research. Part A, Clinical and molecular teratology, 2011, Volume: 91, Issue:2

    Topics: Adolescent; Adult; Caffeine; Case-Control Studies; Congenital Abnormalities; Congenital Microtia; Cr

2011
Risks for birth defects or low birth weight: air pollution...medications...and caffeine.
    Child health alert, 2002, Volume: 20

    Topics: Abnormalities, Drug-Induced; Air Pollutants; Caffeine; Central Nervous System Stimulants; Congenital

2002
[Clinical method to determine serumbilirubin without caffeine].
    Klinische Wochenschrift, 1952, Jun-01, Volume: 30, Issue:21-22

    Topics: Bile Pigments; Caffeine; Congenital Abnormalities; Fractures, Bone; Humans

1952
Effect of caffeine on the metabolism of normal and hypoxic heart muscle.
    Acta physiologica Academiae Scientiarum Hungaricae, 1958, Volume: 14, Issue:2

    Topics: Caffeine; Congenital Abnormalities; Humans; Hypoxia; Myocardium

1958
Congenital malformations in offspring of mice treated with caffeine.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1960, Volume: 104

    Topics: Animals; Caffeine; Congenital Abnormalities; Mice

1960
[Relation between occurrence of hematomas and malformations induced in mouse embryos by administration of a large dosage of caffeine during gestation].
    Kaibogaku zasshi. Journal of anatomy, 1961, Dec-01, Volume: 36

    Topics: Animals; Caffeine; Congenital Abnormalities; Fetus; Hematoma; Mice

1961
Synopsis of the North American Diabetes in Pregnancy Study Group Conference in Little Rock, Arkansas, May 2003.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2004, Volume: 15, Issue:1

    Topics: Blood Glucose; Caffeine; Cesarean Section; Congenital Abnormalities; Delivery, Obstetric; Diabetes,

2004
Coffee in pregnancy.
    Lancet (London, England), 1981, Mar-07, Volume: 1, Issue:8219

    Topics: Caffeine; Coffee; Congenital Abnormalities; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Smok

1981
Food and malformation.
    The Practitioner, 1982, Volume: 226, Issue:1373

    Topics: Abnormalities, Drug-Induced; Caffeine; Congenital Abnormalities; Female; Fetal Alcohol Spectrum Diso

1982
Coffee consumption during pregnancy.
    The New England journal of medicine, 1982, Jun-24, Volume: 306, Issue:25

    Topics: Caffeine; Carbonated Beverages; Coffee; Congenital Abnormalities; Female; Humans; Infant, Newborn; P

1982
Prenatal effects of caffeine and restraint stress in mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1999, Volume: 220, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Caffeine; Congenital Abnormalities; Eating; Embryonic and Feta

1999
Similarity of the mechanism of chemical carcinogen-initiated teratogenesis and carcinogenesis in mice.
    Cancer research, 1977, Volume: 37, Issue:4

    Topics: 4-Nitroquinoline-1-oxide; Abnormalities, Drug-Induced; Animals; Caffeine; Carcinogens; Congenital Ab

1977
An association between certain congenital abnormalities and the malignant hyperthermia trait.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1990, Jun-02, Volume: 77, Issue:11

    Topics: Adolescent; Adult; Caffeine; Child; Child, Preschool; Congenital Abnormalities; Female; Halothane; H

1990
Prevention of caffeine-induced limb malformations by maternal adrenalectomy.
    Teratology, 1986, Volume: 33, Issue:3

    Topics: Adrenal Glands; Adrenalectomy; Animals; Caffeine; Catecholamines; Congenital Abnormalities; Female;

1986
Nutritional teratogens: a survey of epidemiological literature.
    Progress in clinical and biological research, 1985, Volume: 163B

    Topics: Caffeine; Coffee; Congenital Abnormalities; Deficiency Diseases; Diet; Ethanol; Female; Fetal Alcoho

1985