Compounds > cadmium
Page last updated: 2024-08-22

cadmium and Cell Transformation, Neoplastic

cadmium has been researched along with Cell Transformation, Neoplastic in 100 studies

Research

Studies (100)

TimeframeStudies, this research(%)All Research%
pre-199012 (12.00)18.7374
1990's8 (8.00)18.2507
2000's30 (30.00)29.6817
2010's40 (40.00)24.3611
2020's10 (10.00)2.80

Authors

AuthorsStudies
Cirovic, A1
Chang, A; Song, M; Wang, Y; Zhang, L; Zhu, Y; Zhuo, W1
Ankem, MK; Baby, BV; Chandrasekaran, B; Damodaran, C; Navin, AK; Shukla, V; Tyagi, A1
Chen, W; Cui, J; Hua, Q; Huang, L; Jiang, Y; Li, M; Li, X; Lin, Q; Lin, T; Ling, Y; Liu, Y; Qin, X; Zeng, H; Zhang, Y1
Chen, C; Chen, F; Chen, M; Deng, P; Hao, R; Li, J; Li, L; Luo, Y; Pi, H; Tan, M; Tang, B; Tian, L; Wang, H; Xie, J; Yu, Z; Yue, Y; Zhang, H; Zhao, Q; Zhou, Z1
Chiu, JF; Gu, J; Lau, ATY; Liang, ZL; Mo, HY; Tan, HW; Wu, DD; Xu, YM; Yao, Y1
Berindan-Neagoe, I; Gurzau, E; Manda, G; Schitcu, V; Stavaru, C; Szedlacsek, S; Zimta, AA1
Martínez-Pacheco, M; Rodríguez-Sastre, MA; Rojas, E; Valverde, M1
Callegaro, G; Fabbri, M; Forcella, M; Fusi, P; Gribaldo, L; Melchioretto, P; Oldani, M; Urani, C1
Bhat, NS; Dahiya, R; Dasgupta, P; Hashimoto, Y; Kulkarni, P; Majid, S; Saini, S; Shahryari, V; Shiina, M; Tanaka, Y; Yamamura, S1
Cai, X; Huang, Y; Ji, W; Jiang, X; Li, Z; Liu, B; Qi, D; Wu, B; Ying, X; Zhang, H1
Jiang, Q; Li, L; Pan, S; Tu, W; Wang, Q; Zhang, Q; Zhou, X1
Li, L; Pan, S; Wang, Q; Zhang, Q; Zhou, M; Zhou, X1
Kino, K; Kobayashi, T; Miyazawa, H; Nakamura, Y; Oda, M; Okano, T; Sasaki, M; Suzuki, M; Takeda, S; Takiguchi, M; Tanaka, T; Teraoka-Nishitani, N; Waalkes, MP; Yamagata, A; Yamahira, K; Yasuda, N1
Defamie, V; Dela Roca, KT; Evans, CA; Fisher, JM; Khokha, R; Montalvo, MJ; Mulligan, ME; Narala, SR; Voura, EB1
Caristo, ME; Fici, L; Luca, E; Malandrino, P; Marandino, F; Moretti, F; Pontecorvi, A; Ronchi, A; Rossi, ED; Russo, M; Vigneri, R1
Huang, Y; Luo, Y; Shao, M; Yu, Z; Zhang, L; Zhu, Y1
Ankem, MK; Damodaran, C; Freedman, JH; Kolluru, V; Pal, D; Papu John, AMS1
Callegaro, G; Fabbri, M; Forcella, M; Frattini, A; Fusi, P; Gribaldo, L; Melchioretto, P; Urani, C1
Hirao-Suzuki, M; Kino, K; Kobayashi, T; Miyazawa, H; Takeda, S; Takiguchi, M; Waalkes, MP1
Freeberg, BA; Garrett, SH; Hoggarth, ZE; Osowski, DB; Sens, DA; Sens, MA; Somji, S; Zhang, KK; Zhou, XD1
Huang, Y; Ling, J; Xiang, Y; Zhang, L; Zhuo, W1
Ankem, M; Chandrasekaran, B; Damodaran, C; Kolluru, V; Tyagi, A1
Gamage, CDB; Kim, H; Paik, MJ; Park, SY; Son, YJ; Taş, İ; Yang, Y; Zhou, R1
Anetor, JI1
Ngalame, NN; Orihuela, RG; Person, RJ; Tokar, EJ; Waalkes, MP; Xu, Y1
Ngalame, NN; Orihuela, R; Person, RJ; Tokar, EJ; Waalkes, MP; Xu, Y1
Kim, IS; Koedrith, P; Kwon, JY; Park, KS; Seo, YR; Weon, JI1
Bao, Y; Chen, H; Pan, Y; Shao, C; Ye, S; Yuan, D1
Huang, Q; Lei, Y; Liu, H; Wang, C; Wang, M; Zhou, Z1
Garrett, SH; Sens, DA; Somji, S; Zhang, KK1
Rodríguez-Sastre, MA; Rojas, E; Valverde, M1
Hitron, JA; Pratheeshkumar, P; Roy, RV; Shi, X; Son, YO; Wang, L; Zhang, Z1
Bishak, YK; Nourazarian, A; Osatdrahimi, A; Payahoo, L1
Lei, Y; Liu, Q; Shen, H; Zheng, C; Zhou, Z1
Dunlevy, JR; Garrett, SH; Larson-Casey, JL; Sens, DA; Slusser-Nore, A; Somji, S; Zhang, R; Zhou, XD1
Martínez-Baeza, E; Rojas, E; Valverde, M1
Cartularo, L; Cohen, L; Costa, M; Kluz, T; Shen, SS1
Dunlevy, JR; Garrett, SH; Sandquist, EJ; Sens, DA; Slusser-Nore, A; Somji, S; Zhou, XD1
Ngalame, NN; Tokar, EJ; Waalkes, MP1
Dunlevy, JR; Garrett, SH; Sens, DA; Somji, S; Wang, L; Zhang, R; Zhou, XD1
Kawata, K; Okabe, S; Shimazaki, R1
Kadiiska, MB; Liu, J; Qu, W1
Diwan, BA; Klaassen, CD; Liu, J1
Joseph, P1
Benbrahim-Tallaa, L; Coppin, JF; Dill, AL; Diwan, BA; Tokar, EJ; Waalkes, MP1
Chakraborty, PK; Lee, WK; Molitor, M; Thévenod, F; Wolff, NA1
Cao, L; Dunlevy, JR; Garrett, SH; Larson, J; Sens, DA; Sens, MA; Somji, S; Yasmin, T; Zhou, XD1
Cao, L; Dunlevy, JR; Garrett, SH; Larson, JL; Mehus, A; Sens, DA; Sens, MA; Somji, S; Zheng, Y; Zhou, XD1
Agani, F; Barnett, J; Guo, NL; Jiang, BH; Jiang, Y; Jing, Y; Liu, LZ; Rojanasakul, Y; Zhu, Y1
Emilio, R; Mahara, V; Martín, SA1
Allen, C; Dunlevy, JR; Garrett, SH; Sens, DA; Sens, MA; Soh, M; Somji, S; Zhou, XD1
Bell, MW; Kim, AJ; Qu, W; Tokar, EJ; Waalkes, MP1
Budhraja, A; Hitron, JA; Lee, JC; Poyil, P; Shi, X; Son, YO; Wang, L; Zhang, Z1
Bonner, JC; Newman, DR; Sannes, PL; Zhang, H1
Cho, MH; Fang, MZ; Mar, W1
Poirier, LA; Vlasova, TI1
Ong, T; Song, B; Spruill, MD; Whong, WZ1
Achanzar, WE; Li, G; Qu, W; Takiguchi, M; Waalkes, MP1
Gawdi, G; Misra, UK; Pizzo, SV1
Joseph, P; Lei, YX; Ong, TM; Wu, ZL1
Joseph, P; Lei, YX; Ong, TM1
Bortner, CD; Diwan, BA; Liu, J; Pi, J; Qu, W; Reece, JM; Waalkes, MP1
Goyer, RA; Liu, J; Waalkes, MP1
Deckert, J1
Fuquay, R; Qu, W; Sakurai, T; Waalkes, MP1
Garrett, SH; Gurel, V; Park, S; Sens, DA; Sens, MA; Somji, S; Zhou, XD1
Garrett, SH; Sens, DA; Sens, MA; Somji, S; Zhou, XD1
Benbrahim-Tallaa, L; Liu, J; Waalkes, MP; Webber, MM1
Chiu, JF; Lau, AT1
Benbrahim-Tallaa, L; Dill, AL; Waalkes, MP; Waterland, RA; Webber, MM1
Bathula, CS; Garrett, SH; Sens, DA; Sens, MA; Somji, S; Zhou, XD1
Rivedal, E; Sanner, T1
Cathala, G; Karin, M; Nguyen-Huu, MC1
Costa, M; Heck, JD; Robison, SH1
Cutler, ML; Marinetti, MR; Masuelli, L; Tsuda, T1
Rehm, S; Waalkes, MP1
Burke, JF; James, MR; Mayne, LV; Moorwood, K; Price, TN1
Hart, BA; Vacek, PM; Voss, GW1
Abshire, MK; Devor, DE; Diwan, BA; Shaughnessy, JD; Waalkes, MP1
Shiao, YH; Shibata, M; Shimada, H; Waalkes, MP1
Achanzar, WE; Coogan, TP; Waalkes, MP1
Achanzar, WE; Diwan, BA; Liu, J; Quader, ST; Waalkes, MP; Webber, MM1
Cho, MH; Fang, MZ; Mar, WC1
Antonini, JM; Joseph, P; Klishis, ML; Muchnok, TK; Ong , T; Roberts, JR; Whong, WZ1
Cho, MH; Fang, MZ; Kim, DY; Lee, HW1
Joseph, P; Lei, YX; Ong, TM; Whong, WZ1
Ko, D; Moul, JW; Nakamura, K; Peehl, DM; Rhim, JS; Srivastava, S; Xu, LL; Yasunaga, Y1
Alfonso-De Matte, MY; Kruk, PA; Moses-Soto, H1
Lauwerys, R1
Casto, BC; DiPaolo, JA1
Chibber, R; Ord, M1
Fojo, AT; Fornace, AJ; Hall, L; Hamilton, TC; Handel, LM; Monks, A; Ozols, RF; Schilder, RJ1
Sky-Peck, HH1
Bernard, A; Lauwerys, R1
Sunderman, FW1
Best, JB; Hall, F; Morita, M2
Müller, R; Rüther, U; Wagner, EF1
Daniel, M; Edwards, M; Webb, M1

Reviews

13 review(s) available for cadmium and Cell Transformation, Neoplastic

ArticleYear
Iron deficiency as promoter of heavy metals-induced acute myeloid leukemia.
    Leukemia research, 2022, Volume: 112

    Topics: Acute Disease; Anemia, Iron-Deficiency; Antigens, CD; Bone Marrow Cells; Cadmium; Cell Transformation, Neoplastic; Erythroblasts; Humans; Lead; Leukemia, Myeloid; Metals, Heavy; Models, Biological; Receptors, Transferrin

2022
Biological and molecular modifications induced by cadmium and arsenic during breast and prostate cancer development.
    Environmental research, 2019, Volume: 178

    Topics: Arsenic; Breast Neoplasms; Cadmium; Cell Transformation, Neoplastic; Environmental Exposure; Environmental Pollutants; Humans; Male; Metals, Heavy; Prostatic Neoplasms

2019
Rising environmental cadmium levels in developing countries: threat to genome stability and health.
    Nigerian journal of physiological sciences : official publication of the Physiological Society of Nigeria, 2012, Dec-18, Volume: 27, Issue:2

    Topics: Animals; Cadmium; Cadmium Poisoning; Cell Transformation, Neoplastic; Developing Countries; Environmental Pollutants; Genome, Human; Genomic Instability; Humans; Isotopes; Neoplasms

2012
Mechanisms of cadmium carcinogenicity in the gastrointestinal tract.
    Asian Pacific journal of cancer prevention : APJCP, 2015, Volume: 16, Issue:1

    Topics: Apoptosis; Cadmium; Carcinogens; Cell Differentiation; Cell Proliferation; Cell Transformation, Neoplastic; DNA Methylation; DNA Repair; Environmental Pollutants; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Expression; Humans; Methyltransferases; Oxidative Stress; Signal Transduction

2015
Role of oxidative stress in cadmium toxicity and carcinogenesis.
    Toxicology and applied pharmacology, 2009, Aug-01, Volume: 238, Issue:3

    Topics: Adaptation, Physiological; Animals; Apoptosis; Bone Diseases; Cadmium; Cell Transformation, Neoplastic; DNA Damage; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Environmental Pollutants; Gene Expression Regulation, Neoplastic; Humans; Kidney Diseases; Neoplasms; Oxidative Stress; Reactive Oxygen Species; Time Factors

2009
Metallothionein protection of cadmium toxicity.
    Toxicology and applied pharmacology, 2009, Aug-01, Volume: 238, Issue:3

    Topics: Animals; Cadmium; Cell Transformation, Neoplastic; Environmental Pollutants; Humans; Metallothionein; Mice; Neoplasms; Protein Binding

2009
Mechanisms of cadmium carcinogenesis.
    Toxicology and applied pharmacology, 2009, Aug-01, Volume: 238, Issue:3

    Topics: Animals; Apoptosis; Cadmium; Carcinogens, Environmental; Cell Transformation, Neoplastic; DNA Damage; DNA Repair; Gene Expression Regulation, Neoplastic; Humans; Neoplasms; Oxidative Stress; Risk Assessment

2009
Cadmium and cancer of prostate and testis.
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2004, Volume: 17, Issue:5

    Topics: Animals; Cadmium; Carcinogens; Cell Transformation, Neoplastic; Humans; Male; Prostatic Neoplasms; Rats; Testicular Neoplasms; Testosterone; Zinc

2004
Cadmium toxicity in plants: is there any analogy to its carcinogenic effect in mammalian cells?
    Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 2005, Volume: 18, Issue:5

    Topics: Animals; Apoptosis; Cadmium; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Gene Expression Regulation; Humans; Plants; Signal Transduction

2005
Cadmium and prostate cancer.
    Journal of toxicology and environmental health, 1994, Volume: 43, Issue:3

    Topics: Animals; Cadmium; Cell Transformation, Neoplastic; Disease Models, Animal; Environmental Exposure; Humans; Male; Occupational Exposure; Prostate; Prostatic Neoplasms; Rats

1994
[Occupational chemical pollution and cancer].
    Archives belges de medecine sociale, hygiene, medecine du travail et medecine legale. Belgisch archief van sociale geneeskunde, hygiene, arbeidsgeneeskunde en gerechtelijke geneeskunde, 1979, Volume: 37, Issue:6

    Topics: Acrylonitrile; Animals; Arsenic; Asbestosis; Belgium; Benzene Derivatives; Biotransformation; Cadmium; Carcinogens; Cell Transformation, Neoplastic; Chemical Industry; Epoxy Compounds; Humans; Hydrocarbons, Halogenated; Mice; Mining; Neoplasms; Nickel; Nitroso Compounds; Occupational Diseases; Textile Industry; United States

1979
Trace metals and neoplasia.
    Clinical physiology and biochemistry, 1986, Volume: 4, Issue:1

    Topics: Animals; Arsenic; Beryllium; Cadmium; Carcinogens; Cell Transformation, Neoplastic; Chromium; Chromosome Aberrations; DNA; DNA Polymerase I; Environmental Exposure; Gastrointestinal Neoplasms; Humans; In Vitro Techniques; Neoplasms; Neoplasms, Experimental; Nickel; Occupational Diseases; Respiratory Tract Neoplasms; Selenium; Trace Elements

1986
Cadmium in human population.
    Experientia. Supplementum, 1986, Volume: 50

    Topics: Animals; Cadmium; Cadmium Poisoning; Cell Transformation, Neoplastic; Electrophoresis, Agar Gel; Environmental Exposure; Half-Life; Humans; Hypertension; Intestinal Absorption; Kidney; Liver; Lung; Nicotiana; Plants, Toxic; Respiration; Smoking; Tissue Distribution

1986

Other Studies

87 other study(ies) available for cadmium and Cell Transformation, Neoplastic

ArticleYear
Fibronectin 1 as a Key Gene in the Genesis and Progression of Cadmium-Related Bladder Cancer.
    Biological trace element research, 2023, Volume: 201, Issue:9

    Topics: Cadmium; Cell Line; Cell Transformation, Neoplastic; Fibronectins; Gene Expression Regulation, Neoplastic; Humans; Signal Transduction; Urinary Bladder Neoplasms

2023
Molecular interplay between NOX1 and autophagy in cadmium-induced prostate carcinogenesis.
    Free radical biology & medicine, 2023, Volume: 199

    Topics: Activating Transcription Factor 4; Animals; Apoptosis; Autophagy; Cadmium; Cell Transformation, Neoplastic; Endoplasmic Reticulum Stress; Humans; Male; Mice; NADPH Oxidase 1; Prostate; Reactive Oxygen Species

2023
circCIMT Silencing Promotes Cadmium-Induced Malignant Transformation of Lung Epithelial Cells Through the DNA Base Excision Repair Pathway.
    Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2023, Volume: 10, Issue:14

    Topics: Animals; Cadmium; Cell Transformation, Neoplastic; DNA; DNA Repair; Epithelial Cells; Lung; Mice

2023
Environmental cadmium exposure facilitates mammary tumorigenesis via reprogramming gut microbiota-mediated glutamine metabolism in MMTV-Erbb2 mice.
    The Science of the total environment, 2023, Nov-01, Volume: 897

    Topics: Animals; Cadmium; Carcinogenesis; Cell Transformation, Neoplastic; Gastrointestinal Microbiome; Glutamine; Ki-67 Antigen; Mammary Neoplasms, Experimental; Mice; Mice, Transgenic; Necrosis

2023
Lasting DNA Damage and Aberrant DNA Repair Gene Expression Profile Are Associated with Post-Chronic Cadmium Exposure in Human Bronchial Epithelial Cells.
    Cells, 2019, 08-06, Volume: 8, Issue:8

    Topics: Adenocarcinoma; Air Pollutants; Cadmium; Carcinoma, Squamous Cell; Cell Line; Cell Transformation, Neoplastic; Databases, Genetic; DNA Damage; DNA Repair; Epithelial Cells; Humans; Lung; Lung Neoplasms

2019
As-Cd-Pb Mixture Induces Cellular Transformation via Post-Transcriptional Regulation of Rad51c by miR-222.
    Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 2019, Volume: 53, Issue:6

    Topics: Animals; Antagomirs; Arsenic; BALB 3T3 Cells; Cadmium; Cell Survival; Cell Transformation, Neoplastic; DNA Breaks, Double-Stranded; DNA-Binding Proteins; Gene Expression Regulation; Lead; Metals, Heavy; Mice; MicroRNAs; Rad51 Recombinase

2019
In vitro and bioinformatics mechanistic-based approach for cadmium carcinogenicity understanding.
    Toxicology in vitro : an international journal published in association with BIBRA, 2020, Volume: 65

    Topics: Animals; Cadmium; Carcinogenesis; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Computational Biology; Cytokines; Gene Expression Regulation, Neoplastic; Mice

2020
Role of the PI3K/Akt pathway in cadmium induced malignant transformation of normal prostate epithelial cells.
    Toxicology and applied pharmacology, 2020, 12-15, Volume: 409

    Topics: Animals; Cadmium; Carcinogenesis; Cell Line; Cell Line, Tumor; Cell Transformation, Neoplastic; Cohort Studies; Down-Regulation; Epithelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Phosphatidylinositol 3-Kinases; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins c-akt; Signal Transduction; Up-Regulation

2020
Integrated analysis of mRNA-m
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2021, Volume: 26, Issue:6

    Topics: Cadmium; Cell Line, Transformed; Cell Transformation, Neoplastic; Gene Expression Profiling; Humans; Methyltransferases; Proteomics; RNA, Messenger; Sequence Analysis, RNA; Urinary Bladder Neoplasms; Urothelium

2021
CircSPAG16 suppresses cadmium-induced transformation of human bronchial epithelial cells by decoying PIP5K1α to inactivate Akt.
    Molecular carcinogenesis, 2021, Volume: 60, Issue:8

    Topics: Biomarkers; Cadmium; Cell Transformation, Neoplastic; Cells, Cultured; Disease Susceptibility; Epithelial Cells; Gene Expression Regulation; Humans; Microtubule-Associated Proteins; Phosphotransferases (Alcohol Group Acceptor); Proto-Oncogene Proteins c-akt; Respiratory Mucosa; RNA, Circular

2021
A novel circular RNA, circPUS7 promotes cadmium-induced transformation of human bronchial epithelial cells by regulating Kirsten rat sarcoma viral oncogene homolog expression via sponging miR-770.
    Metallomics : integrated biometal science, 2021, 07-24, Volume: 13, Issue:7

    Topics: Apoptosis; Bronchi; Cadmium; Cell Cycle; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Epithelial Cells; Gene Expression Regulation, Neoplastic; Humans; Intramolecular Transferases; Lung Neoplasms; MicroRNAs; Neoplasm Invasiveness; Proto-Oncogene Proteins p21(ras); RNA, Circular

2021
Cadmium-induced malignant transformation of rat liver cells: Potential key role and regulatory mechanism of altered apolipoprotein E expression in enhanced invasiveness.
    Toxicology, 2017, 05-01, Volume: 382

    Topics: Animals; Apolipoproteins E; ATP Binding Cassette Transporter 1; Benzoates; Benzylamines; Cadmium; Carcinogens; Cell Line; Cell Movement; Cell Transformation, Neoplastic; DNA Methylation; Liver; Liver X Receptors; Rats; Sterol Regulatory Element Binding Protein 1

2017
Planarians as models of cadmium-induced neoplasia provide measurable benchmarks for mechanistic studies.
    Ecotoxicology and environmental safety, 2017, Volume: 142

    Topics: Animals; Benchmarking; Cadmium; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Mitosis; Models, Biological; Planarians; Regeneration

2017
Intake of Boron, Cadmium, and Molybdenum enhances rat thyroid cell transformation.
    Journal of experimental & clinical cancer research : CR, 2017, 06-02, Volume: 36, Issue:1

    Topics: Animals; Boron; Cadmium; Cell Transformation, Neoplastic; Female; Molybdenum; Rats; Rats, Wistar; Thyroid Neoplasms

2017
Identification and Characterization of Cadmium-Related Genes in Liver Carcinoma.
    Biological trace element research, 2018, Volume: 182, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amino Acid Transport System y+; Cadmium; Cell Transformation, Neoplastic; Databases, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Integrin alpha2; Liver; Liver Neoplasms; Male; Middle Aged; Transcriptome

2018
Induction of Plac8 promotes pro-survival function of autophagy in cadmium-induced prostate carcinogenesis.
    Cancer letters, 2017, 11-01, Volume: 408

    Topics: Animals; Apoptosis; Autophagy; Cadmium; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Prostate; Prostatic Neoplasms; Proteins; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2017
Toxicogenomics applied to in vitro Cell Transformation Assay reveals mechanisms of early response to cadmium.
    Toxicology in vitro : an international journal published in association with BIBRA, 2018, Volume: 48

    Topics: Animals; Cadmium; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Gene Expression Regulation; Glutathione Transferase; Metallothionein; Mice; Mice, Inbred C3H; Microarray Analysis; Receptors, Odorant; Signal Transduction; Toxicogenetics; Zinc

2018
Cadmium down-regulates apolipoprotein E (ApoE) expression during malignant transformation of rat liver cells: direct evidence for DNA hypermethylation in the promoter region of ApoE.
    The Journal of toxicological sciences, 2018, Volume: 43, Issue:9

    Topics: Animals; Apolipoproteins E; Cadmium; Cell Transformation, Neoplastic; Cells, Cultured; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression; Liver Neoplasms; Promoter Regions, Genetic; Rats, Inbred F344

2018
The urothelial cell line UROtsa transformed by arsenite and cadmium display basal characteristics associated with muscle invasive urothelial cancers.
    PloS one, 2018, Volume: 13, Issue:12

    Topics: Animals; Arsenites; Biomarkers, Tumor; Cadmium; Cell Differentiation; Cell Line, Transformed; Cell Transformation, Neoplastic; Heterografts; Humans; Immunohistochemistry; Mice; Mice, Nude; Models, Biological; Neoplasm Invasiveness; Neoplasm Transplantation; Neoplastic Stem Cells; Spheroids, Cellular; Transcriptome; Urinary Bladder Neoplasms; Urothelium

2018
Microarray-based data mining reveals key genes and potential therapeutic drugs for Cadmium-induced prostate cell malignant transformation.
    Environmental toxicology and pharmacology, 2019, Volume: 68

    Topics: Antineoplastic Agents; Cadmium; Cell Transformation, Neoplastic; Data Mining; Endoplasmic Reticulum Chaperone BiP; Environmental Pollutants; Gene Expression Regulation, Neoplastic; Humans; Male; Microarray Analysis; Prostatic Neoplasms

2019
Induction of endoplasmic reticulum stress might be responsible for defective autophagy in cadmium-induced prostate carcinogenesis.
    Toxicology and applied pharmacology, 2019, 06-15, Volume: 373

    Topics: Autophagy; Autophagy-Related Proteins; Cadmium; Cell Line, Transformed; Cell Transformation, Neoplastic; Endoplasmic Reticulum Stress; Epithelial Cells; Humans; Male; Oxidative Stress; Phosphorylation; Prostate; Prostatic Neoplasms; Reactive Oxygen Species; Signal Transduction; Superoxide Dismutase; Superoxide Dismutase-1

2019
Inflammatory and tumorigenic effects of environmental pollutants found in particulate matter on lung epithelial cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2019, Volume: 59

    Topics: Benzene; Benzo(a)pyrene; Cadmium; Carcinogens; Cell Line; Cell Membrane Permeability; Cell Transformation, Neoplastic; Environmental Pollutants; Epithelial Cells; Humans; Inflammation; Lung; NF-kappa B; Particulate Matter; Phthalic Acids; STAT3 Transcription Factor

2019
Recruitment of normal stem cells to an oncogenic phenotype by noncontiguous carcinogen-transformed epithelia depends on the transforming carcinogen.
    Environmental health perspectives, 2013, Volume: 121, Issue:8

    Topics: Animals; Blotting, Western; Cadmium; Carcinogens; Carcinoma; Cell Line, Tumor; Cell Transformation, Neoplastic; Environmental Pollutants; Epithelial Cells; Fluorescent Antibody Technique; Gene Expression Regulation, Neoplastic; Humans; Male; Matrix Metalloproteinases; Methylnitrosourea; Mice; Mice, Nude; Neoplastic Stem Cells; Polymerase Chain Reaction; Prostatic Neoplasms; Transforming Growth Factor alpha

2013
Chronic cadmium exposure in vitro induces cancer cell characteristics in human lung cells.
    Toxicology and applied pharmacology, 2013, Dec-01, Volume: 273, Issue:2

    Topics: Cadmium; Cell Transformation, Neoplastic; DNA Damage; Humans; Lung; Lung Neoplasms; Oxidative Stress; Respiratory Mucosa; Time Factors; Tumor Cells, Cultured

2013
Identification of molecular candidates and interaction networks via integrative toxicogenomic analysis in a human cell line following low-dose exposure to the carcinogenic metals cadmium and nickel.
    Oncology reports, 2013, Volume: 30, Issue:3

    Topics: Biomarkers, Tumor; Cadmium; Carcinogens; Cell Transformation, Neoplastic; Colonic Neoplasms; Comparative Genomic Hybridization; Dose-Response Relationship, Drug; Endoplasmic Reticulum Chaperone BiP; Gene Expression Profiling; Humans; Nickel; Oligonucleotide Array Sequence Analysis; Protein Interaction Maps; Proteomics; Signal Transduction; Toxicogenetics; Trace Elements; Tumor Cells, Cultured

2013
Long-term cadmium exposure leads to the enhancement of lymphocyte proliferation via down-regulating p16 by DNA hypermethylation.
    Mutation research, 2013, Oct-09, Volume: 757, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; B-Lymphocytes; Cadmium; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Decitabine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression Regulation; Granulocyte-Macrophage Progenitor Cells; Humans; Rats; RNA, Messenger; Time Factors

2013
Cadmium induced cell apoptosis, DNA damage, decreased DNA repair capacity, and genomic instability during malignant transformation of human bronchial epithelial cells.
    International journal of medical sciences, 2013, Volume: 10, Issue:11

    Topics: Animals; Apoptosis; Bronchi; Cadmium; Cell Transformation, Neoplastic; DNA Damage; DNA Repair; Epithelial Cells; Genomic Instability; Humans; Mice

2013
Prediction of the number of activated genes in multiple independent Cd(+2)- and As(+3)-induced malignant transformations of human urothelial cells (UROtsa).
    PloS one, 2014, Volume: 9, Issue:1

    Topics: Algorithms; Arsenic; Cadmium; Cell Line; Cell Transformation, Neoplastic; Cluster Analysis; Computational Biology; Computer Simulation; Epithelial Cells; Humans; Models, Genetic; Oligonucleotide Array Sequence Analysis; Reverse Transcriptase Polymerase Chain Reaction; Transcriptome; Urothelium

2014
Assessing the impact of As-Cd-Pb metal mixture on cell transformation by two-stage Balb/c 3T3 cell assay.
    Mutagenesis, 2014, Volume: 29, Issue:4

    Topics: 3T3 Cells; Animals; Arsenic; Biological Assay; Cadmium; Cell Cycle; Cell Survival; Cell Transformation, Neoplastic; Cellular Senescence; DNA Damage; Humans; Lead; Metallothionein; Metals, Heavy; Mice; Mice, Inbred BALB C; Mutagenicity Tests; Reactive Oxygen Species

2014
Nrf2/p62 signaling in apoptosis resistance and its role in cadmium-induced carcinogenesis.
    The Journal of biological chemistry, 2014, Oct-10, Volume: 289, Issue:41

    Topics: Animals; Apoptosis; Autophagy; bcl-X Protein; Bronchi; Cadmium; Catalase; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression Regulation, Neoplastic; Genes, Reporter; Green Fluorescent Proteins; Humans; Lung Neoplasms; Male; Mice; Mice, Nude; Microtubule-Associated Proteins; Neoplasm Transplantation; NF-E2-Related Factor 2; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; RNA-Binding Proteins; RNA, Small Interfering; Signal Transduction; Superoxide Dismutase

2014
MicroRNAs-mRNAs Expression Profile and Their Potential Role in Malignant Transformation of Human Bronchial Epithelial Cells Induced by Cadmium.
    BioMed research international, 2015, Volume: 2015

    Topics: Cadmium; Cell Line; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression Profiling; Humans; MicroRNAs; RNA, Messenger

2015
SPARC Expression Is Selectively Suppressed in Tumor Initiating Urospheres Isolated from As+3- and Cd+2-Transformed Human Urothelial Cells (UROtsa) Stably Transfected with SPARC.
    PloS one, 2016, Volume: 11, Issue:1

    Topics: Animals; Arsenites; Cadmium; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Down-Regulation; Epithelial Cells; Gene Expression Regulation; Humans; Mice; Neoplasm Transplantation; Neoplastic Stem Cells; Osteonectin; Urothelium

2016
Metal mixture (As-Cd-Pb)-induced cell transformation is modulated by OLA1.
    Mutagenesis, 2016, Volume: 31, Issue:4

    Topics: Adenosine Triphosphatases; Animals; Arsenic; Cadmium; Cell Line; Cell Transformation, Neoplastic; Environmental Pollutants; Gene Knockdown Techniques; Lead; Mice; Oxidative Stress; RNA, Small Interfering

2016
Molecular Mechanisms of Malignant Transformation by Low Dose Cadmium in Normal Human Bronchial Epithelial Cells.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Autophagy; Bronchi; Cadmium; Carcinogens; Cell Adhesion Molecules, Neuronal; Cell Line; Cell Movement; Cell Survival; Cell Transformation, Neoplastic; DNA Damage; DNA Modification Methylases; DNA Repair Enzymes; Epigenesis, Genetic; Epithelial Cells; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Gene Silencing; Humans; Oxidative Stress; Phenotype; Respiratory Mucosa; Time Factors; Tumor Suppressor Proteins

2016
Loss of N-Cadherin Expression in Tumor Transplants Produced From As+3- and Cd+2-Transformed Human Urothelial (UROtsa) Cell Lines.
    PloS one, 2016, Volume: 11, Issue:5

    Topics: Aldehyde Dehydrogenase 1 Family; Animals; Antigens, CD; Arsenites; Cadherins; Cadmium; Cell Line, Tumor; Cell Transformation, Neoplastic; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Isoenzymes; Mice; Neoplasm Transplantation; Retinal Dehydrogenase; Spheroids, Cellular; Urinary Bladder Neoplasms; Urothelium

2016
Silencing KRAS Overexpression in Cadmium-Transformed Prostate Epithelial Cells Mitigates Malignant Phenotype.
    Chemical research in toxicology, 2016, 09-19, Volume: 29, Issue:9

    Topics: Cadmium; Cell Line; Cell Proliferation; Cell Transformation, Neoplastic; Epithelial Cells; Gene Expression; Gene Knockdown Techniques; Gene Silencing; Humans; Male; Prostate; Prostatic Neoplasms; Proto-Oncogene Proteins p21(ras); Signal Transduction

2016
Elevated connexin 43 expression in arsenite-and cadmium-transformed human bladder cancer cells, tumor transplants and selected high grade human bladder cancers.
    Experimental and toxicologic pathology : official journal of the Gesellschaft fur Toxikologische Pathologie, 2016, Volume: 68, Issue:9

    Topics: Animals; Arsenites; Biomarkers, Tumor; Cadmium; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Connexin 43; Heterografts; Humans; Immunohistochemistry; Mice; Mice, Nude; Polymerase Chain Reaction; Urinary Bladder Neoplasms

2016
Comparison of gene expression profiles in HepG2 cells exposed to arsenic, cadmium, nickel, and three model carcinogens for investigating the mechanisms of metal carcinogenesis.
    Environmental and molecular mutagenesis, 2009, Volume: 50, Issue:1

    Topics: Arsenic; Base Sequence; Cadmium; Carcinogens; Cell Line; Cell Transformation, Neoplastic; DNA Primers; Gene Expression Profiling; Humans; Nickel; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction

2009
Cadmium malignantly transforms normal human breast epithelial cells into a basal-like phenotype.
    Environmental health perspectives, 2009, Volume: 117, Issue:12

    Topics: Animals; Aromatase; Breast Neoplasms; Cadmium; Cell Line, Tumor; Cell Transformation, Neoplastic; Estrogen Receptor alpha; Female; Humans; Keratin-5; Membrane Proteins; Mice; Phenotype

2009
Cadmium induces Wnt signaling to upregulate proliferation and survival genes in sub-confluent kidney proximal tubule cells.
    Molecular cancer, 2010, May-08, Volume: 9

    Topics: Animals; Basic Helix-Loop-Helix Leucine Zipper Transcription Factors; beta Catenin; Cadherins; Cadmium; Carcinogens; Cell Proliferation; Cell Transformation, Neoplastic; Cells, Cultured; Electrophoretic Mobility Shift Assay; Humans; Immunoblotting; Immunoprecipitation; Kidney Tubules, Proximal; Microscopy, Confocal; Microscopy, Fluorescence; Rats; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Transcription Factor 4; Transcription Factors; Transfection; Up-Regulation; Wnt Proteins

2010
SPARC gene expression is repressed in human urothelial cells (UROtsa) exposed to or malignantly transformed by cadmium or arsenite.
    Toxicology letters, 2010, Nov-30, Volume: 199, Issue:2

    Topics: Acetylation; Arsenites; Cadmium; Cell Transformation, Neoplastic; Cells, Cultured; Cystitis; DNA Methylation; Gene Expression Regulation; Humans; Osteonectin; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium

2010
Comparison of expression patterns of keratin 6, 7, 16, 17, and 19 within multiple independent isolates of As(+3)- and Cd (+2)-induced bladder cancer : keratin 6, 7, 16, 17, and 19 in bladder cancer.
    Cell biology and toxicology, 2011, Volume: 27, Issue:6

    Topics: Animals; Arsenites; Biomarkers, Tumor; Blotting, Western; Cadmium; Cell Line; Cell Transformation, Neoplastic; Gene Expression Regulation, Neoplastic; Humans; Keratins; Mice; Mice, Nude; Neoplasm Transplantation; Real-Time Polymerase Chain Reaction; RNA, Messenger; Transplantation, Heterologous; Urinary Bladder Neoplasms; Urothelium

2011
Cadmium increases HIF-1 and VEGF expression through ROS, ERK, and AKT signaling pathways and induces malignant transformation of human bronchial epithelial cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2012, Volume: 125, Issue:1

    Topics: Animals; Blotting, Western; Bronchi; Cadmium; Cell Culture Techniques; Cell Line; Cell Transformation, Neoplastic; Chick Embryo; Chorioallantoic Membrane; Dose-Response Relationship, Drug; Epithelial Cells; Female; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; MAP Kinase Signaling System; Mice; Microscopy, Fluorescence; Neoplasm Transplantation; Neovascularization, Pathologic; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Time Factors; Vascular Endothelial Growth Factor A

2012
Role of oxidative stress in transformation induced by metal mixture.
    Oxidative medicine and cellular longevity, 2011, Volume: 2011

    Topics: Acetylcysteine; Air Pollutants; Animals; Arsenic; BALB 3T3 Cells; Cadmium; Carcinogens, Environmental; Cell Survival; Cell Transformation, Neoplastic; Free Radical Scavengers; Humans; Lead; Mice; Oxidative Stress; Reactive Oxygen Species

2011
Increased neuron specific enolase expression by urothelial cells exposed to or malignantly transformed by exposure to Cd²⁺ or As³⁺.
    Toxicology letters, 2012, Jul-07, Volume: 212, Issue:1

    Topics: Animals; Arsenites; Benzamides; Cadmium; Cell Line, Tumor; Cell Transformation, Neoplastic; Histone Deacetylase Inhibitors; Humans; Immunohistochemistry; Mice; Mice, Nude; Phosphopyruvate Hydratase; Pyridines; Real-Time Polymerase Chain Reaction; RNA, Messenger; Urinary Bladder; Urologic Neoplasms; Urothelium

2012
Chronic cadmium exposure in vitro causes acquisition of multiple tumor cell characteristics in human pancreatic epithelial cells.
    Environmental health perspectives, 2012, Volume: 120, Issue:9

    Topics: Cadmium; Cell Line; Cell Transformation, Neoplastic; Environmental Pollutants; Gene Expression Regulation, Neoplastic; Humans; Neoplastic Stem Cells; Pancreatic Neoplasms; Spheroids, Cellular

2012
Cadmium induces carcinogenesis in BEAS-2B cells through ROS-dependent activation of PI3K/AKT/GSK-3β/β-catenin signaling.
    Toxicology and applied pharmacology, 2012, Oct-15, Volume: 264, Issue:2

    Topics: Animals; beta Catenin; Blotting, Western; Bronchi; Cadmium; Carcinogens; Cell Line; Cell Movement; Cell Transformation, Neoplastic; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Humans; Mice; Mice, Nude; Neoplasm Invasiveness; Oncogene Protein v-akt; Phosphatidylinositol 3-Kinases; Plasmids; Reactive Oxygen Species; Respiratory Mucosa; Signal Transduction; Transfection; Xenograft Model Antitumor Assays

2012
Over-expression of human endosulfatase-1 exacerbates cadmium-induced injury to transformed human lung cells in vitro.
    Toxicology and applied pharmacology, 2012, Nov-15, Volume: 265, Issue:1

    Topics: Adenoviridae; Apoptosis; Blotting, Western; Cadmium; Cell Count; Cell Line, Tumor; Cell Survival; Cell Transformation, Neoplastic; Coloring Agents; Down-Regulation; Heparan Sulfate Proteoglycans; Humans; In Situ Nick-End Labeling; Lac Operon; Lung; Polymerase Chain Reaction; Respiratory Mucosa; Sulfotransferases; Tetrazolium Salts; Thiazoles; Transduction, Genetic; Up-Regulation

2012
Cadmium affects genes involved in growth regulation during two-stage transformation of Balb/3T3 cells.
    Toxicology, 2002, Aug-15, Volume: 177, Issue:2-3

    Topics: 3T3 Cells; Animals; Cadmium; Cell Division; Cell Transformation, Neoplastic; DNA Damage; Gene Expression; Genes, myc; Methylnitronitrosoguanidine; Mice; Microfilament Proteins; Muscle Proteins; Nuclear Proteins; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-mdm2; RNA, Messenger; Tumor Suppressor Protein p53

2002
The prospective role of abnormal methyl metabolism in cadmium toxicity.
    Environmental health perspectives, 2002, Volume: 110 Suppl 5

    Topics: Administration, Oral; Animals; Cadmium; Cell Transformation, Neoplastic; DNA Methylation; DNA Modification Methylases; Kinetics; Rats; Zinc

2002
Proto-oncogene amplification and overexpression in cadmium-induced cell transformation.
    Journal of toxicology and environmental health. Part A, 2002, Dec-27, Volume: 65, Issue:24

    Topics: Animals; Blotting, Western; Cadmium; Cell Transformation, Neoplastic; Chromosome Painting; DNA; DNA Primers; Electrophoresis, Agar Gel; Electrophoresis, Polyacrylamide Gel; Gene Expression; Genes, jun; Genes, myc; Mice; Mice, Inbred BALB C; Mutation; Polymorphism, Restriction Fragment Length; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tumor Cells, Cultured

2002
Effects of cadmium on DNA-(Cytosine-5) methyltransferase activity and DNA methylation status during cadmium-induced cellular transformation.
    Experimental cell research, 2003, Jun-10, Volume: 286, Issue:2

    Topics: Animals; Binding Sites; Cadmium; Carcinogens; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA; DNA Methylation; Dose-Response Relationship, Drug; Drug Administration Schedule; Eukaryotic Cells; Gene Expression Regulation, Enzymologic; Methyltransferases; Neoplasm Invasiveness; Protein Structure, Tertiary; Rats; Rats, Inbred F344; Up-Regulation

2003
Induction of mitogenic signalling in the 1LN prostate cell line on exposure to submicromolar concentrations of cadmium+.
    Cellular signalling, 2003, Volume: 15, Issue:11

    Topics: 3-Phosphoinositide-Dependent Protein Kinases; Bacterial Proteins; Cadmium; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; Enterotoxins; Humans; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; NF-kappa B; Phosphatidylinositol 3-Kinases; Phosphorylation; Prostate; Protein Serine-Threonine Kinases; Protein Subunits; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Thymidylate Synthase; Type C Phospholipases

2003
[Effect of aberrant DNA methylation on the expression of cancer-related genes in Cd-transformed cells].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2003, Volume: 21, Issue:2

    Topics: Animals; BALB 3T3 Cells; Blotting, Southern; Cadmium; Cell Transformation, Neoplastic; CpG Islands; DNA Methylation; Genes, p16; Mice; Restriction Mapping

2003
Up-regulation of expression of translation factors--a novel molecular mechanism for cadmium carcinogenesis.
    Molecular and cellular biochemistry, 2004, Volume: 255, Issue:1-2

    Topics: 3T3 Cells; Animals; Cadmium; Cell Transformation, Neoplastic; DNA, Complementary; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Mice; Mice, Nude; Molecular Sequence Data; Peptide Elongation Factor 1; Prokaryotic Initiation Factor-3; Recombinant Proteins; Up-Regulation

2004
Cadmium-induced malignant transformation in rat liver cells: role of aberrant oncogene expression and minimal role of oxidative stress.
    International journal of cancer, 2005, Apr-10, Volume: 114, Issue:3

    Topics: Animals; Cadmium; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Epithelial Cells; Gene Expression Profiling; Gene Expression Regulation; Liver; Liver Neoplasms; Oncogenes; Oxidative Stress; Rats; Rats, Inbred F344; Reactive Oxygen Species; Transcription Factors

2005
Acquisition of apoptotic resistance in cadmium-induced malignant transformation: specific perturbation of JNK signal transduction pathway and associated metallothionein overexpression.
    Molecular carcinogenesis, 2006, Volume: 45, Issue:8

    Topics: Animals; Apoptosis; Cadmium; Cell Transformation, Neoplastic; Cells, Cultured; Indoles; JNK Mitogen-Activated Protein Kinases; Liver; Metallothionein; Mitogen-Activated Protein Kinase 8; Mitogen-Activated Protein Kinase 9; Phosphorylation; Protein Kinase Inhibitors; Rats; Signal Transduction; Up-Regulation

2006
Enhanced expression of metallothionein isoform 3 protein in tumor heterotransplants derived from As+3- and Cd+2-transformed human urothelial cells.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 93, Issue:2

    Topics: Animals; Arsenic; Biomarkers, Tumor; Breast Neoplasms; Cadmium; Cell Transformation, Neoplastic; Cells, Cultured; Female; Humans; Immunohistochemistry; Male; Metallothionein; Metallothionein 3; Mice; Neoplasm Transplantation; Prostatic Neoplasms; Protein Isoforms; RNA, Messenger; Transplantation, Heterologous; Urinary Bladder Neoplasms

2006
Urothelial cells malignantly transformed by exposure to cadmium (Cd(+2)) and arsenite (As(+3)) have increased resistance to Cd(+2) and As(+3)-induced cell death.
    Toxicological sciences : an official journal of the Society of Toxicology, 2006, Volume: 94, Issue:2

    Topics: Apoptosis; Arsenites; Cadmium; Caspases; Cell Line, Transformed; Cell Transformation, Neoplastic; DNA Fragmentation; Dose-Response Relationship, Drug; Drug Resistance, Multiple; Humans; L-Lactate Dehydrogenase; Metallothionein; Necrosis; Urothelium

2006
Estrogen signaling and disruption of androgen metabolism in acquired androgen-independence during cadmium carcinogenesis in human prostate epithelial cells.
    The Prostate, 2007, Feb-01, Volume: 67, Issue:2

    Topics: Androgen Antagonists; Androgens; Cadmium; Cell Line, Transformed; Cell Proliferation; Cell Transformation, Neoplastic; Dihydrotestosterone; Disease Progression; Epithelial Cells; Estradiol; Estrogens; Flutamide; Gene Expression Regulation; Humans; Male; Prostate; Prostatic Neoplasms; Receptors, Androgen; Receptors, Estrogen; RNA, Messenger; Signal Transduction

2007
The possible role of cytokeratin 8 in cadmium-induced adaptation and carcinogenesis.
    Cancer research, 2007, Mar-01, Volume: 67, Issue:5

    Topics: Animals; Cadmium; Cell Transformation, Neoplastic; Cells, Cultured; Drug Resistance; Gene Silencing; Keratin-14; Keratin-8; Mitogen-Activated Protein Kinase 1; Models, Biological; Proteome; Rats; Time

2007
Tumor suppressor gene inactivation during cadmium-induced malignant transformation of human prostate cells correlates with overexpression of de novo DNA methyltransferase.
    Environmental health perspectives, 2007, Volume: 115, Issue:10

    Topics: Cadmium; Carcinogens, Environmental; Case-Control Studies; Cell Transformation, Neoplastic; Cells, Cultured; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3B; Epithelial Cells; Gene Expression Profiling; Gene Expression Regulation; Genes, Tumor Suppressor; Humans; Male; Prostate; Up-Regulation

2007
Transformation of human urothelial cells (UROtsa) by as and cd induces the expression of keratin 6a.
    Environmental health perspectives, 2008, Volume: 116, Issue:4

    Topics: Animals; Arsenites; Biomarkers, Tumor; Blotting, Western; Cadmium; Cell Line; Cell Transformation, Neoplastic; Culture Media; Epidermal Growth Factor; Humans; Immunohistochemistry; Insulin; Keratin-6; Mice; Mice, Nude; Neoplasm Transplantation; Polymerase Chain Reaction; RNA, Messenger; Transplantation, Heterologous; Urinary Bladder Neoplasms; Urothelium

2008
Metal salts as promoters of in vitro morphological transformation of hamster embryo cells initiated by benzo(a)pyrene.
    Cancer research, 1981, Volume: 41, Issue:7

    Topics: Animals; Benzo(a)pyrene; Benzopyrenes; Cadmium; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Drug Synergism; Mesocricetus; Nickel; Potassium; Salts

1981
Expression and regulation of a human metallothionein gene carried on an autonomously replicating shuttle vector.
    Proceedings of the National Academy of Sciences of the United States of America, 1983, Volume: 80, Issue:13

    Topics: Animals; Base Sequence; Bovine papillomavirus 1; Cadmium; Cell Line; Cell Transformation, Neoplastic; DNA Replication; DNA Restriction Enzymes; Genes; Humans; Metalloproteins; Metallothionein; Papillomaviridae; Plasmids; Rats; RNA, Messenger; Virus Replication

1983
Selective phagocytosis of crystalline metal sulfide particles and DNA strand breaks as a mechanism for the induction of cellular transformation.
    Cancer research, 1982, Volume: 42, Issue:7

    Topics: Animals; Cadmium; Cadmium Compounds; Cell Transformation, Neoplastic; Cells, Cultured; Cobalt; Cricetinae; Cricetulus; Crystallization; DNA; Latex; Mesocricetus; Microspheres; Nickel; Phagocytosis; Sulfides

1982
The Ras suppressor RSU-1 localizes to 10p13 and its expression in the U251 glioblastoma cell line correlates with a decrease in growth rate and tumorigenic potential.
    Oncogene, 1995, Jul-20, Volume: 11, Issue:2

    Topics: Animals; Cadmium; Cell Division; Cell Transformation, Neoplastic; Chromosome Mapping; Chromosomes, Human, Pair 10; Cricetinae; DNA, Complementary; Gene Expression; Genes, ras; Genes, Tumor Suppressor; Glioblastoma; Humans; In Situ Hybridization; Metallothionein; Mice; Mice, Nude; Phenotype; Promoter Regions, Genetic; Transfection; Tumor Cells, Cultured

1995
Cell cycle progression, morphology and contact inhibition are regulated by the amount of SV40 T antigen in immortal human cells.
    Oncogene, 1994, Volume: 9, Issue:10

    Topics: Adult; Antigens, Polyomavirus Transforming; Cadmium; Cell Communication; Cell Cycle; Cell Division; Cell Transformation, Neoplastic; Electroporation; Fibroblasts; Genetic Vectors; Humans; Plasmids; Zinc

1994
Metallothionein in human lung carcinoma.
    Cancer letters, 1993, Dec-10, Volume: 75, Issue:2

    Topics: Adenocarcinoma; Aged; Biomarkers, Tumor; Cadmium; Cadmium Radioisotopes; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Chromatography, Agarose; Copper; Humans; Lung; Lung Neoplasms; Melanoma; Metallothionein; Middle Aged; Neoplasm Proteins; Protein Binding; Spectrophotometry, Atomic

1993
In vitro exposure to cadmium in rat L6 myoblasts can result in both enhancement and suppression of malignant progression in vivo.
    Carcinogenesis, 1996, Volume: 17, Issue:6

    Topics: Animals; Anticarcinogenic Agents; Base Sequence; Cadmium; Carcinogens; Cell Division; Cell Transformation, Neoplastic; Disease Progression; Gene Expression; Genes, jun; Genes, myc; Male; Metallothionein; Mice; Mice, Nude; Molecular Sequence Data; Muscle Neoplasms; Muscle, Skeletal; Neoplasm Transplantation; Rats; RNA, Messenger

1996
Cadmium suppresses apoptosis induced by chromium.
    Journal of toxicology and environmental health. Part A, 1998, May-22, Volume: 54, Issue:2

    Topics: Animals; Apoptosis; Cadmium; Carcinogens; Cell Transformation, Neoplastic; CHO Cells; Chromium; Cricetinae; Cricetulus; Drug Interactions; In Vitro Techniques; Metallothionein

1998
Spontaneous transformation of cultured rat liver (TRL 1215) cells is associated with down-regulation of metallothionein: implications for sensitivity to cadmium cytotoxicity and genotoxicity.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2000, Volume: 19, Issue:3

    Topics: Animals; Cadmium; Cell Adhesion; Cell Division; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Damage; Down-Regulation; Gene Expression; Liver; Metallothionein; Rats; Rats, Inbred F344

2000
Cadmium-induced malignant transformation of human prostate epithelial cells.
    Cancer research, 2001, Jan-15, Volume: 61, Issue:2

    Topics: Adenocarcinoma; Animals; Cadmium; Cell Transformation, Neoplastic; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Prostate; Prostate-Specific Antigen; Transplantation, Heterologous

2001
Cadmium-induced alterations of connexin expression in the promotion stage of in vitro two-stage transformation.
    Toxicology, 2001, Mar-21, Volume: 161, Issue:1-2

    Topics: Animals; Blotting, Western; Cadmium; Cell Transformation, Neoplastic; Cells, Cultured; Connexins; Gap Junctions; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C

2001
Cadmium-induced cell transformation and tumorigenesis are associated with transcriptional activation of c-fos, c-jun, and c-myc proto-oncogenes: role of cellular calcium and reactive oxygen species.
    Toxicological sciences : an official journal of the Society of Toxicology, 2001, Volume: 61, Issue:2

    Topics: 3T3 Cells; Analysis of Variance; Animals; Blotting, Northern; Cadmium; Calcium; Cell Transformation, Neoplastic; Dactinomycin; Egtazic Acid; Flavonoids; Free Radical Scavengers; Gene Expression Regulation, Neoplastic; Genes, fos; Genes, jun; Genes, myc; Indoles; Mice; Mice, Inbred BALB C; Mitogen-Activated Protein Kinase Kinases; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; RNA; Tumor Cells, Cultured

2001
Improvement of in vitro two-stage transformation assay and determination of the promotional effect of cadmium.
    Toxicology in vitro : an international journal published in association with BIBRA, 2001, Volume: 15, Issue:3

    Topics: 3T3 Cells; Animals; Cadmium; Carcinogenicity Tests; Carcinogens; Cell Line; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; In Vitro Techniques; Methylnitronitrosoguanidine; Mice; Mice, Inbred BALB C; Polychlorinated Dibenzodioxins; Tetradecanoylphorbol Acetate; Time Factors

2001
Oncogenic potential of mouse translation elongation factor-1 delta, a novel cadmium-responsive proto-oncogene.
    The Journal of biological chemistry, 2002, Feb-22, Volume: 277, Issue:8

    Topics: 3T3 Cells; Amino Acid Sequence; Animals; Cadmium; Cell Line, Transformed; Cell Transformation, Neoplastic; CHO Cells; Cricetinae; DNA, Complementary; Gene Expression Regulation; Humans; Mice; Molecular Sequence Data; Neoplasms, Experimental; Open Reading Frames; Peptide Elongation Factor 1; Proto-Oncogene Mas; Proto-Oncogenes; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Transcription, Genetic; Transfection; Xenopus

2002
Cadmium-induced neoplastic transformation of human prostate epithelial cells.
    International journal of oncology, 2002, Volume: 20, Issue:3

    Topics: Adenocarcinoma; Animals; Cadmium; Cell Transformation, Neoplastic; Epithelial Cells; Humans; Karyotyping; Keratins; Male; Mice; Mice, SCID; Prostate-Specific Antigen; Prostatic Neoplasms; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; Simian virus 40; Time Factors; Tumor Cells, Cultured

2002
Calcium-mediated telomerase activity in ovarian epithelial cells.
    Archives of biochemistry and biophysics, 2002, Mar-15, Volume: 399, Issue:2

    Topics: Cadmium; Calcium; Cell Transformation, Neoplastic; Cells, Cultured; Chromium; Epithelial Cells; Female; Humans; Ovarian Neoplasms; Telomerase; Tumor Cells, Cultured; Verapamil

2002
Quantitative studies of in vitro morphological transformation of Syrian hamster cells by inorganic metal salts.
    Cancer research, 1979, Volume: 39, Issue:3

    Topics: Animals; Arsenic; Beryllium; Cadmium; Cell Transformation, Neoplastic; Cells, Cultured; Chromium; Cricetinae; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Maternal-Fetal Exchange; Mesocricetus; Metals; Nickel; Pregnancy

1979
Cadmium-induced multistep transformation of cultured Indian muntjac skin fibroblasts.
    Biology of metals, 1990, Volume: 3, Issue:3-4

    Topics: Actins; Animals; Cadmium; Cell Cycle; Cell Division; Cell Line; Cell Transformation, Neoplastic; Cytoskeleton; Deer; Fibroblasts; Fibronectins; Fluorescent Antibody Technique; Mice; Mice, Nude; Skin; Tubulin

1990
Metallothionein gene expression and resistance to cisplatin in human ovarian cancer.
    International journal of cancer, 1990, Mar-15, Volume: 45, Issue:3

    Topics: Cadmium; Cell Survival; Cell Transformation, Neoplastic; Cisplatin; Drug Resistance; Female; Gene Expression Regulation, Neoplastic; Humans; Metallothionein; Ovarian Neoplasms; RNA, Neoplasm; Tumor Cells, Cultured

1990
Carcinogenicity and mutagenicity of some metals and their compounds.
    IARC scientific publications, 1986, Issue:71

    Topics: Animals; Arsenic; Cadmium; Carcinogens; Cell Transformation, Neoplastic; Chromium; Chromosome Aberrations; DNA; DNA Damage; DNA-Directed DNA Polymerase; Humans; Metals; Microsomes, Liver; Mutagens; Nickel; Nucleoproteins; Platinum; Tin; Transcription, Genetic

1986
Neoplastic transformation in the planarian: I. Cocarcinogenesis and histopathology.
    The Journal of experimental zoology, 1986, Volume: 240, Issue:2

    Topics: Animals; Cadmium; Cadmium Compounds; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Planarians; Sulfates; Tetradecanoylphorbol Acetate; Turbellaria

1986
Neoplastic transformation in the planarian: II. Ultrastructure of malignant reticuloma.
    The Journal of experimental zoology, 1986, Volume: 240, Issue:2

    Topics: Animals; Cadmium; Cadmium Compounds; Carcinogens; Cell Transformation, Neoplastic; Cocarcinogenesis; Planarians; Sulfates; Tetradecanoylphorbol Acetate; Turbellaria

1986
Analysis of the differentiation-promoting potential of inducible c-fos genes introduced into embryonal carcinoma cells.
    The EMBO journal, 1985, Volume: 4, Issue:7

    Topics: Animals; Cadmium; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Clone Cells; Fluorescent Antibody Technique; Mice; Oncogenes; Plasmids; Teratoma; Transfection

1985
The effect of mental-serum complexes on differentiating muscle in vitro.
    British journal of experimental pathology, 1974, Volume: 55, Issue:3

    Topics: Animals; Blood Proteins; Cadmium; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chick Embryo; Cobalt; Ligands; Muscles; Nickel; Zinc

1974