bz-423 has been researched along with Lupus Erythematosus, Systemic in 5 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (100.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bednarski, JJ; Blatt, NB; Boitano, A; Ellman, JA; Glick, GD; Johnson, KJ; Johnson, KM; Leonetti, F; Opipari, AW; Richardson, BC; Warner, RE; Yung, R | 1 |
Habeck, M | 1 |
Bednarski, JJ; Boitano, AE; Glick, GD; Lyssiotis, CA; Opipari, AW; Roush, R | 1 |
Gestwicki, JE | 1 |
Boitano, A; Chen, X; Glick, GD; Johnson, KM; Opipari, AW; Swenson, L | 1 |
5 other study(ies) available for bz-423 and Lupus Erythematosus, Systemic
Article | Year |
---|---|
Benzodiazepine-induced superoxide signals B cell apoptosis: mechanistic insight and potential therapeutic utility.
Topics: Animals; Antibodies, Antinuclear; Apoptosis; B-Lymphocytes; Benzodiazepines; Cell Line, Transformed; Female; Humans; In Vitro Techniques; Lupus Erythematosus, Systemic; Mice; Mice, Inbred NZB; Models, Biological; Reactive Oxygen Species; Signal Transduction; Superoxides | 2002 |
Benzodiazepine library yields lupus target.
Topics: Animals; Benzodiazepines; Combinatorial Chemistry Techniques; Drug Delivery Systems; Humans; Lupus Erythematosus, Systemic | 2002 |
A novel benzodiazepine increases the sensitivity of B cells to receptor stimulation with synergistic effects on calcium signaling and apoptosis.
Topics: Animals; Apoptosis; B-Lymphocytes; Benzodiazepines; Calcium; Calcium Signaling; Cells, Cultured; Chelating Agents; Disease Models, Animal; Egtazic Acid; Female; Fluorescent Dyes; Germinal Center; Humans; Lupus Erythematosus, Systemic; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Molecular Structure; Receptors, Antigen, B-Cell; Superoxides | 2004 |
Target identification for a promising anti-lupus drug.
Topics: Adenosine Triphosphatases; Animals; Benzodiazepines; Drug Design; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Immunologic Factors; Lupus Erythematosus, Systemic; Mitochondrial Proton-Translocating ATPases; Peptide Library | 2005 |
Identification and validation of the mitochondrial F1F0-ATPase as the molecular target of the immunomodulatory benzodiazepine Bz-423.
Topics: Adenosine Triphosphatases; Animals; Benzodiazepines; Carrier Proteins; Cattle; Cell Death; Cell Line; Cloning, Molecular; Drug Evaluation, Preclinical; Enzyme Inhibitors; Humans; Immunologic Factors; Indicators and Reagents; Lupus Erythematosus, Systemic; Membrane Proteins; Mitochondria; Mitochondria, Heart; Mitochondrial Proton-Translocating ATPases; Oxygen Consumption; RNA, Small Interfering; Transfection | 2005 |