butyric acid has been researched along with Thalassemias in 5 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because butyrate and alpha-amino-n-butyric acid (ABA) augment gamma globin expression in normal neonatal and adult erythroid progenitors, we investigated the effects of sodium butyrate and ABA on erythroid progenitors of patients with beta thalassemia and sickle cell anemia who might benefit from such an effect." | 3.67 | Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia. ( Cohen, RA; Faller, DV; Hurst, D; Lubin, BH; Miller, BA; Papayannopoulou, T; Perrine, SP; Vichinsky, EP, 1989) |
| " However, application of these drugs at large is not yet justified because a series of questions concerning their long-term efficacy, the correct dosage and timing, their tolerance and toxicity, and the potential long-term dangers, including mutagenicity are still unresolved." | 2.40 | New therapies for the haemoglobinopathies. ( Loukopoulos, D, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rochette, J | 1 |
| Craig, JE | 1 |
| Thein, SL | 1 |
| Loukopoulos, D | 1 |
| Perrine, SP | 3 |
| Faller, DV | 3 |
| Swerdlow, P | 2 |
| Miller, BA | 2 |
| Bank, A | 1 |
| Sytkowski, AJ | 1 |
| Reczek, J | 2 |
| Rudolph, AM | 2 |
| Kan, YW | 2 |
| Cohen, RA | 1 |
| Vichinsky, EP | 1 |
| Hurst, D | 1 |
| Lubin, BH | 1 |
| Papayannopoulou, T | 1 |
| Qin, G | 1 |
2 reviews available for butyric acid and Thalassemias
| Article | Year |
|---|---|
Fetal hemoglobin levels in adults.
Topics: Adult; Azacitidine; Base Sequence; Butyrates; Butyric Acid; Fetal Hemoglobin; Gene Expression Regula | 1994 |
New therapies for the haemoglobinopathies.
Topics: Anemia, Sickle Cell; Antisickling Agents; Butyrates; Butyric Acid; Drug Therapy, Combination; Erythr | 1997 |
3 other studies available for butyric acid and Thalassemias
| Article | Year |
|---|---|
Stopping the biologic clock for globin gene switching.
Topics: Anemia, Sickle Cell; Animals; Biological Clocks; Butyrates; Butyric Acid; Cell Line; Cells, Cultured | 1990 |
Sodium butyrate enhances fetal globin gene expression in erythroid progenitors of patients with Hb SS and beta thalassemia.
Topics: Anemia, Sickle Cell; Butyrates; Butyric Acid; Cells, Cultured; Child; Child, Preschool; Erythropoies | 1989 |
Butyric acid modulates developmental globin gene switching in man and sheep.
Topics: Acetylation; Adult; Anemia, Sickle Cell; Animals; Butyrates; Butyric Acid; Fetal Hemoglobin; Gene Ex | 1989 |