butyric acid has been researched along with Retinoblastoma in 18 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Retinoblastoma: A malignant tumor arising from the nuclear layer of the retina that is the most common primary tumor of the eye in children. The tumor tends to occur in early childhood or infancy and may be present at birth. The majority are sporadic, but the condition may be transmitted as an autosomal dominant trait. Histologic features include dense cellularity, small round polygonal cells, and areas of calcification and necrosis. An abnormal pupil reflex (leukokoria); NYSTAGMUS, PATHOLOGIC; STRABISMUS; and visual loss represent common clinical characteristics of this condition. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, p2104)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We studied the release of melatonin and the production of its precursors, 5-hydroxytryptophan and serotonin, in cultured Y79 human retinoblastoma cells." | 7.68 | Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate. ( Deng, MH; Lopez G-Coviella, I; Lynch, HJ; Wurtman, RJ, 1991) |
| "Melatonin is synthesized by cultured Y79 human retinoblastoma cells and is secreted into the medium." | 7.68 | Cyclic AMP and butyrate modulate melatonin synthesis in Y79 human retinoblastoma cells. ( Chader, GJ; Fletcher, RT; Kyritsis, AP; Wiechmann, AF, 1990) |
| "The effects of butyrate, retinol, and retinoic acid were tested on growth and differentiation of human Y-79 retinoblastoma cells in monolayer cultures." | 7.67 | Effects of butyrate, retinol, and retinoic acid on human Y-79 retinoblastoma cells growing in monolayer cultures. ( Chader, GJ; Joseph, G; Kyritsis, A, 1984) |
| "Using bromodeoxyuridine (BrdU) and an anti-BrdU monoclonal antibody (Mab), the fraction of cells in S phase of the Y79 human retinoblastoma line maintained in an organ culture system was determined." | 7.67 | Determination by anti-bromodeoxyuridine monoclonal antibody of cells in S phase in the human Y79 retinoblastoma line maintained in an organ culture system: effects of butyric acid. ( Nakagawa, Y; Perentes, E, 1987) |
| "Two key enzymes involved in the synthesis of melatonin, hydroxyindole-O-methyltransferase (HIOMT) and arylalkylamine N-acetyltransferase (AA-NAT), are present in Y79 human retinoblastoma cells." | 3.70 | Regulation of AA-NAT and HIOMT gene expression by butyrate and cyclic AMP in Y79 human retinoblastoma cells. ( Burden, MA; Wiechmann, AF, 1999) |
| "We studied the release of melatonin and the production of its precursors, 5-hydroxytryptophan and serotonin, in cultured Y79 human retinoblastoma cells." | 3.68 | Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate. ( Deng, MH; Lopez G-Coviella, I; Lynch, HJ; Wurtman, RJ, 1991) |
| "Melatonin is synthesized by cultured Y79 human retinoblastoma cells and is secreted into the medium." | 3.68 | Cyclic AMP and butyrate modulate melatonin synthesis in Y79 human retinoblastoma cells. ( Chader, GJ; Fletcher, RT; Kyritsis, AP; Wiechmann, AF, 1990) |
| "The effects of butyrate, retinol, and retinoic acid were tested on growth and differentiation of human Y-79 retinoblastoma cells in monolayer cultures." | 3.67 | Effects of butyrate, retinol, and retinoic acid on human Y-79 retinoblastoma cells growing in monolayer cultures. ( Chader, GJ; Joseph, G; Kyritsis, A, 1984) |
| "Using bromodeoxyuridine (BrdU) and an anti-BrdU monoclonal antibody (Mab), the fraction of cells in S phase of the Y79 human retinoblastoma line maintained in an organ culture system was determined." | 3.67 | Determination by anti-bromodeoxyuridine monoclonal antibody of cells in S phase in the human Y79 retinoblastoma line maintained in an organ culture system: effects of butyric acid. ( Nakagawa, Y; Perentes, E, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (50.00) | 18.7374 |
| 1990's | 9 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kyritsis, A | 2 |
| Joseph, G | 1 |
| Chader, GJ | 10 |
| Gaudet, SJ | 1 |
| Hayden, BJ | 1 |
| Namboodiri, MA | 1 |
| Conway, RM | 2 |
| Madigan, MC | 2 |
| Penfold, PL | 2 |
| Billson, FA | 2 |
| Wiechmann, AF | 3 |
| Lauricella, M | 1 |
| Giuliano, M | 1 |
| Emanuele, S | 1 |
| Vento, R | 1 |
| Tesoriere, G | 1 |
| Burden, MA | 1 |
| Deng, MH | 1 |
| Lopez G-Coviella, I | 1 |
| Lynch, HJ | 1 |
| Wurtman, RJ | 1 |
| Howard, MA | 1 |
| Wardwell, S | 1 |
| Albert, DM | 1 |
| Kyritsis, AP | 6 |
| Fletcher, RT | 2 |
| Tsokos, M | 2 |
| Triche, TJ | 2 |
| Campbell, MA | 1 |
| Karras, P | 1 |
| Pennypacker, KR | 1 |
| Billingsley, ML | 1 |
| Kapoor, CL | 1 |
| Nakagawa, Y | 1 |
| Perentes, E | 1 |
| Wiggert, B | 1 |
| Lee, L | 1 |
18 other studies available for butyric acid and Retinoblastoma
| Article | Year |
|---|---|
Effects of butyrate, retinol, and retinoic acid on human Y-79 retinoblastoma cells growing in monolayer cultures.
Topics: Butyrates; Butyric Acid; Cell Division; Cell Line; Cell Survival; Eye Neoplasms; Humans; Kinetics; R | 1984 |
Differential regulation of arylamine and arylalkylamine N-acetyltransferases in human retinoblastoma (Y-79) cells.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Arylamine N-Acetyltransferase; Bucladesine; Butyrates; Butyr | 1993 |
Induction of apoptosis by sodium butyrate in the human Y-79 retinoblastoma cell line.
Topics: Apoptosis; Aurintricarboxylic Acid; Butyrates; Butyric Acid; Cell Adhesion; Cell Division; Cell Surv | 1995 |
Recoverin in cultured human retinoblastoma cells: enhanced expression during morphological differentiation.
Topics: Antibody Specificity; Antigens, Neoplasm; Biomarkers, Tumor; Blotting, Northern; Blotting, Western; | 1996 |
Apoptotic effects of different drugs on cultured retinoblastoma Y79 cells.
Topics: Amsacrine; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Apoptosis; Butyrates; Butyric A | 1998 |
Vincristine- and cisplatin-induced apoptosis in human retinoblastoma. Potentiation by sodium butyrate.
Topics: Antineoplastic Agents; Apoptosis; Butyric Acid; Cisplatin; DNA, Neoplasm; Dose-Response Relationship | 1998 |
Regulation of AA-NAT and HIOMT gene expression by butyrate and cyclic AMP in Y79 human retinoblastoma cells.
Topics: Acetylserotonin O-Methyltransferase; Arylamine N-Acetyltransferase; Base Sequence; Bucladesine; Buty | 1999 |
Melatonin and its precursors in Y79 human retinoblastoma cells: effect of sodium butyrate.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Butyrates; Butyric Acid; Cell Line; Colforsin; Dopamine; | 1991 |
Effect of butyrate and corticosteroids on retinoblastoma in vitro and in vivo.
Topics: Animals; Butyrates; Butyric Acid; Cell Division; Drug Synergism; Drug Therapy, Combination; Eye Neop | 1991 |
Cyclic AMP and butyrate modulate melatonin synthesis in Y79 human retinoblastoma cells.
Topics: Acetylserotonin O-Methyltransferase; Arylamine N-Acetyltransferase; Bucladesine; Butyrates; Butyric | 1990 |
Retinoblastoma: a primitive tumor with multipotential characteristics.
Topics: Bucladesine; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Eye Neoplasms; Humans; Micros | 1986 |
Y-79 retinoblastoma cells: isolation and characterization of clonal lineages.
Topics: Bucladesine; Butyrates; Butyric Acid; Cell Count; Cell Line; Cell Survival; Eye Neoplasms; Humans; L | 1989 |
Calmodulin-binding proteins in human Y-79 retinoblastoma and HTB-14 glioma cell lines.
Topics: Biotin; Bucladesine; Butyrates; Butyric Acid; Calmodulin-Binding Proteins; Cell Differentiation; Cel | 1988 |
Differentiation of human retinoblastoma in vitro into cell types with characteristics observed in embryonal or mature retina.
Topics: Bucladesine; Butyrates; Butyric Acid; Cell Differentiation; Cells; Cells, Cultured; Cytological Tech | 1986 |
Laminin: an initiating role in retinoblastoma cell attachment and differentiation.
Topics: Antibodies; Bucladesine; Butyrates; Butyric Acid; Cell Adhesion; Cell Line; Cell Transformation, Neo | 1986 |
Distribution of the regulatory subunit of type II cAMP-dependent protein kinase in Y-79 retinoblastoma cells. Effect of butyrate.
Topics: Biological Transport; Butyrates; Butyric Acid; Carrier Proteins; Cell Division; Cell Line; Cell Nucl | 1986 |
Determination by anti-bromodeoxyuridine monoclonal antibody of cells in S phase in the human Y79 retinoblastoma line maintained in an organ culture system: effects of butyric acid.
Topics: Antibodies, Monoclonal; Bromodeoxyuridine; Butyrates; Butyric Acid; Cell Line; Eye Neoplasms; Humans | 1987 |
Butyrate enhances the synthesis of interphotoreceptor retinoid-binding protein (IRBP) by Y-79 human retinoblastoma cells.
Topics: Amino Acids; Butyrates; Butyric Acid; Cell Line; Electrophoresis, Polyacrylamide Gel; Eye Proteins; | 1985 |