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butyric acid and Prostatic Neoplasms

butyric acid has been researched along with Prostatic Neoplasms in 10 studies

Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.

Prostatic Neoplasms: Tumors or cancer of the PROSTATE.

Research Excerpts

ExcerptRelevanceReference
"Hypoacetylation on histone H3 of human prostate cancer cells has been described."1.43Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells. ( Cang, S; Chiao, JW; Liu, D; Ma, Y; Xu, X, 2016)
"Prostate cancer is a major cause of male cancer death."1.31Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A. ( Brown, G; Campbell, MJ; Driver, PM; Edwards, CE; Engel, J; Moore, JS; Rashid, SF; Uskokovic, MR; Walker, E, 2001)
"Exposure of prostate cancer cell lines to PB reduces their DNA synthesis, leads to fragmentation of genomic DNA, and causes 50-60% of cells to undergo apoptosis."1.29Phenylbutyrate induces apoptosis in human prostate cancer and is more potent than phenylacetate. ( Ayyagari, SR; Campbell, PA; Carducci, MA; Chan-Tack, KM; Nelson, JB; Nelson, WG; Simons, JW; Sweatt, WH, 1996)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19902 (20.00)18.7374
1990's1 (10.00)18.2507
2000's2 (20.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Paskova, L1
Smesny Trtkova, K1
Fialova, B1
Benedikova, A1
Langova, K1
Kolar, Z1
Mu, D1
Gao, Z1
Guo, H1
Zhou, G1
Sun, B1
Maggio, A1
Magli, A1
Rancati, T1
Fiorino, C1
Valvo, F1
Fellin, G1
Ricardi, U1
Munoz, F1
Cosentino, D1
Cazzaniga, LF1
Valdagni, R1
Vavassori, V1
Weaver, EM1
Zamora, FJ1
Puplampu-Dove, YA1
Kiessu, E1
Hearne, JL1
Martin-Caraballo, M1
Cang, S1
Xu, X1
Ma, Y1
Liu, D1
Chiao, JW1
Sonnemann, J1
Gänge, J1
Kumar, KS1
Müller, C1
Bader, P1
Beck, JF1
Carducci, MA1
Nelson, JB1
Chan-Tack, KM1
Ayyagari, SR1
Sweatt, WH1
Campbell, PA1
Nelson, WG1
Simons, JW1
Rashid, SF1
Moore, JS1
Walker, E1
Driver, PM1
Engel, J1
Edwards, CE1
Brown, G1
Uskokovic, MR1
Campbell, MJ1
Halgunset, J1
Lamvik, T1
Espevik, T1
Reese, DH1
Gratzner, HG1
Block, NL1
Politano, VA1

Reviews

1 review available for butyric acid and Prostatic Neoplasms

ArticleYear
Histone deacetylase inhibitors interact synergistically with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis in carcinoma cell lines.
    Investigational new drugs, 2005, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Butyric Acid; Caspase 3; Caspases;

2005

Trials

1 trial available for butyric acid and Prostatic Neoplasms

ArticleYear
Daily sodium butyrate enema for the prevention of radiation proctitis in prostate cancer patients undergoing radical radiation therapy: results of a multicenter randomized placebo-controlled dose-finding phase 2 study.
    International journal of radiation oncology, biology, physics, 2014, Jul-01, Volume: 89, Issue:3

    Topics: Acute Disease; Administration, Rectal; Analysis of Variance; Antineoplastic Agents, Hormonal; Butyri

2014

Other Studies

8 other studies available for butyric acid and Prostatic Neoplasms

ArticleYear
Different effect of sodium butyrate on cancer and normal prostate cells.
    Toxicology in vitro : an international journal published in association with BIBRA, 2013, Volume: 27, Issue:5

    Topics: Acetylation; Butyric Acid; Cell Line; Cell Line, Tumor; Cell Survival; Gene Expression Regulation; H

2013
Sodium butyrate induces growth inhibition and apoptosis in human prostate cancer DU145 cells by up-regulation of the expression of annexin A1.
    PloS one, 2013, Volume: 8, Issue:9

    Topics: Annexin A1; Apoptosis; Butyric Acid; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Respo

2013
Regulation of T-type calcium channel expression by sodium butyrate in prostate cancer cells.
    European journal of pharmacology, 2015, Feb-15, Volume: 749

    Topics: Butyric Acid; Calcium Channels, T-Type; Cell Differentiation; Cell Line; Cell Line, Tumor; Cell Prol

2015
Hypoacetylation, hypomethylation, and dephosphorylation of H2B histones and excessive histone deacetylase activity in DU-145 prostate cancer cells.
    Journal of hematology & oncology, 2016, Jan-12, Volume: 9

    Topics: Acetylation; Amino Acid Sequence; Butyric Acid; Cell Line; Cell Line, Tumor; Chromatography, Liquid;

2016
Phenylbutyrate induces apoptosis in human prostate cancer and is more potent than phenylacetate.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1996, Volume: 2, Issue:2

    Topics: Animals; Antineoplastic Agents; Apoptosis; Butyric Acid; DNA; Humans; Male; Phenylacetates; Phenylbu

1996
Synergistic growth inhibition of prostate cancer cells by 1 alpha,25 Dihydroxyvitamin D(3) and its 19-nor-hexafluoride analogs in combination with either sodium butyrate or trichostatin A.
    Oncogene, 2001, Apr-05, Volume: 20, Issue:15

    Topics: Antineoplastic Agents; Apoptosis; Butyric Acid; Calcitriol; Cell Cycle; Cholecalciferol; Cyclin-Depe

2001
Butyrate effects on growth, morphology, and fibronectin production in PC-3 prostatic carcinoma cells.
    The Prostate, 1988, Volume: 12, Issue:1

    Topics: Actin Cytoskeleton; Butyrates; Butyric Acid; Cell Division; Fibronectins; Fluorescent Antibody Techn

1988
Control of growth, morphology, and alkaline phosphatase activity by butyrate and related short-chain fatty acids in the retinoid-responsive 9-1C rat prostatic adenocarcinoma cell.
    Cancer research, 1985, Volume: 45, Issue:5

    Topics: Adenocarcinoma; Alkaline Phosphatase; Animals; Butyrates; Butyric Acid; Cell Cycle; Cell Line; Fatty

1985