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butyric acid and Pancreatic Neoplasms

butyric acid has been researched along with Pancreatic Neoplasms in 18 studies

Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
"We previously demonstrated that two human pancreatic adenocarcinoma cell lines, CFPAC-1 (established from a patient with cystic fibrosis) and CAPAN-1, were able to secrete trypsinogens 1 and 2 specifically."3.69Trypsinogen expression by two human pancreatic cell lines CFPAC-1 and CAPAN-1. Modulation during spontaneous and induced cell growth. ( Figarella, C; Guy-Crotte, O; Merten, M; Miszczuk-Jamska, B; Renaud, W, 1994)
" In this study we examined the effects of two agents that promote cellular differentiation, sodium butyrate and hexamethylene bisacetamide, on the in vitro growth and secretory responses of a human pancreatic carcinoid (BON) and human gastrinoma (PT-2 and PT-SM) cell lines that have been established in our laboratory."3.68Differential effects of sodium butyrate and hexamethylene bisacetamide on growth and secretion of cultured human endocrine tumor cells. ( Beauchamp, RD; Haber, BE; Hsieh, J; Ishizuka, J; Karp, G; Parekh, D; Rajaraman, S; Thompson, JC; Townsend, CM, 1991)

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19907 (38.89)18.7374
1990's9 (50.00)18.2507
2000's0 (0.00)29.6817
2010's1 (5.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Sanaei, M1
Kavoosi, F1
Almaraz, RT1
Aich, U1
Khanna, HS1
Tan, E1
Bhattacharya, R1
Shah, S1
Yarema, KJ1
Green, R1
Shields, D1
McIntyre, LJ1
Kim, YS2
Miszczuk-Jamska, B1
Merten, M1
Renaud, W1
Guy-Crotte, O1
Figarella, C1
Corra, S1
Kazakoff, K1
Mogaki, M1
Cano, M1
Pour, PM1
Swarovsky, B1
Eissele, R1
Eisenacher, M1
Trautmann, ME2
Arnold, R1
Fernandez-Mejia, C1
Davidson, MB1
Egawa, N1
Maillet, B1
VanDamme, B1
De Grève, J1
Klöppel, G1
Estival, A1
Clerc, P1
Vaysse, N1
Tam, JP1
Clemente, F1
Parekh, D1
Ishizuka, J1
Townsend, CM1
Haber, BE1
Beauchamp, RD1
Rajaraman, S1
Karp, G1
Hsieh, J1
Thompson, JC1
Mullins, TD1
Kern, HF1
Metzgar, RS1
Blondel, B1
Gjinovci, A1
Wollheim, CB1
Bartholomeusz, RK1
Campbell, IL1
Harrison, LC1
Gardner, SL1
Dotta, F1
Nayak, RC1
George, KL1
Eisenbarth, GS1
Halban, PA1
Bloom, EJ1
Siddiqui, B1
Hicks, JW1
Bryant, G1
Haberern, C1
Rao, CN1
Liotta, LA1
el-Deriny, SE1
O'Brien, MJ1
Christensen, TG1
Kupchik, HZ1

Other Studies

18 other studies available for butyric acid and Pancreatic Neoplasms

ArticleYear
Effect of Sodium Butyrate on p16INK4a, p14ARF, p15INK4b, Class I HDACs (HDACs 1, 2, 3) Class II HDACs (HDACs 4, 5, 6), Cell Growth Inhibition and Apoptosis Induction in Pancreatic Cancer AsPC-1 and Colon Cancer HCT-116 Cell Lines.
    Asian Pacific journal of cancer prevention : APJCP, 2022, Mar-01, Volume: 23, Issue:3

    Topics: Apoptosis; Butyric Acid; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent

2022
Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations.
    Biotechnology and bioengineering, 2012, Volume: 109, Issue:4

    Topics: Acylation; Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Azides; Breast Neoplasms; Buty

2012
Sodium butyrate stimulates somatostatin production by cultured cells.
    Endocrinology, 1984, Volume: 114, Issue:6

    Topics: Adenoma, Islet Cell; Animals; Butyrates; Butyric Acid; Cell Line; HeLa Cells; Humans; Insulinoma; Ki

1984
Effects of sodium butyrate and dimethylsulfoxide on human pancreatic tumor cell lines.
    European journal of cancer & clinical oncology, 1984, Volume: 20, Issue:2

    Topics: Agar; Alkaline Phosphatase; Amylases; Butyrates; Butyric Acid; Cell Adhesion; Cell Division; Cell Li

1984
Trypsinogen expression by two human pancreatic cell lines CFPAC-1 and CAPAN-1. Modulation during spontaneous and induced cell growth.
    International journal of pancreatology : official journal of the International Association of Pancreatology, 1994, Volume: 16, Issue:1

    Topics: Adenocarcinoma; Butyrates; Butyric Acid; Cell Division; Dexamethasone; Dimethyl Sulfoxide; Humans; P

1994
Modification of antigen expression in human and hamster pancreatic cancer cell lines induced by sodium butyrate.
    Teratogenesis, carcinogenesis, and mutagenesis, 1993, Volume: 13, Issue:5

    Topics: ABO Blood-Group System; Adenocarcinoma; Animals; Antigens, Neoplasm; Blood Group Antigens; Butyrates

1993
Sodium butyrate induces neuroendocrine cytodifferentiation in the insulinoma cell line RINm5F.
    Pancreas, 1994, Volume: 9, Issue:4

    Topics: Blotting, Northern; Butyrates; Butyric Acid; Cell Differentiation; Chromogranin A; Chromogranins; Cy

1994
Effect of sodium butyrate on glucose transport and glucose-phosphorylating enzymes in RIN-m5F cells.
    Pancreas, 1993, Volume: 8, Issue:5

    Topics: Animals; Biological Transport; Butyrates; Butyric Acid; Cell Division; Glucokinase; Glucose; Glucose

1993
Differentiation of pancreatic carcinoma induced by retinoic acid or sodium butyrate: a morphological and molecular analysis of four cell lines.
    Virchows Archiv : an international journal of pathology, 1996, Volume: 429, Issue:1

    Topics: Blotting, Northern; Blotting, Western; Butyrates; Butyric Acid; Carcinoma, Ductal, Breast; CD57 Anti

1996
Decreased expression of transforming growth factor alpha during differentiation of human pancreatic cancer cells.
    Gastroenterology, 1992, Volume: 103, Issue:6

    Topics: Butyrates; Butyric Acid; Cell Differentiation; Gene Expression Regulation; Humans; Pancreatic Neopla

1992
Differential effects of sodium butyrate and hexamethylene bisacetamide on growth and secretion of cultured human endocrine tumor cells.
    Archives of surgery (Chicago, Ill. : 1960), 1991, Volume: 126, Issue:4

    Topics: 5-Hydroxytryptophan; Acetamides; Analysis of Variance; Butyrates; Butyric Acid; Carcinoid Tumor; Cel

1991
Ultrastructural differentiation of sodium butyrate-treated human pancreatic adenocarcinoma cell lines.
    Pancreas, 1991, Volume: 6, Issue:5

    Topics: Adenocarcinoma; Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Division; Cell Transformation, N

1991
Inverse relationship between glucose metabolism and glucose-induced insulin secretion in rat insulinoma cells.
    Hormone research, 1990, Volume: 34, Issue:2

    Topics: Animals; Butyrates; Butyric Acid; Cell Line; Dose-Response Relationship, Drug; Glucose; Glyceraldehy

1990
Pancreatic islet A2B5- and 3G5-reactive gangliosides are markers of differentiation in rat insulinoma cells.
    Endocrinology, 1989, Volume: 124, Issue:6

    Topics: Adenoma, Islet Cell; Animals; Antibodies, Monoclonal; Butyrates; Butyric Acid; Cell Differentiation;

1989
Modulation by sodium butyrate of the differentiated status of a clonal pancreatic B-cell line (RIN).
    Diabetes research (Edinburgh, Scotland), 1989, Volume: 12, Issue:2

    Topics: Animals; Antibodies, Monoclonal; Autoantibodies; Butyrates; Butyric Acid; Cell Differentiation; Cell

1989
Effect of sodium butyrate, a differentiating agent, on cell surface glycoconjugates of a human pancreatic cell line.
    Pancreas, 1989, Volume: 4, Issue:1

    Topics: Butyrates; Butyric Acid; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; G

1989
Butyrate induced reduction of tumor cell laminin receptors.
    Cancer research, 1986, Volume: 46, Issue:2

    Topics: Adenocarcinoma; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Gene Expression Regulation

1986
Ultrastructural differentiation and CEA expression of butyrate-treated human pancreatic carcinoma cells.
    Pancreas, 1987, Volume: 2, Issue:1

    Topics: Adenocarcinoma; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Differentiation; Cell Divisi

1987