butyric acid has been researched along with Obesity in 36 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).
Excerpt | Relevance | Reference |
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"This study demonstrates that ECD regulates the gut microbiota and promotes butyric acid production to ameliorate obesity-related hepatic steatosis." | 8.31 | Erchen Decoction alleviates obesity-related hepatic steatosis via modulating gut microbiota-drived butyric acid contents and promoting fatty acid β-oxidation. ( Bi, T; Chen, N; Zhan, L; Zhang, L; Zhou, W; Zhu, L, 2023) |
"This study demonstrates that ECD regulates the gut microbiota and promotes butyric acid production to ameliorate obesity-related hepatic steatosis." | 4.31 | Erchen Decoction alleviates obesity-related hepatic steatosis via modulating gut microbiota-drived butyric acid contents and promoting fatty acid β-oxidation. ( Bi, T; Chen, N; Zhan, L; Zhang, L; Zhou, W; Zhu, L, 2023) |
"Acetic acid, propionic acid, butyric acid, and total SCFA were significantly reduced in T2D patients compared to overweight/obese in the unadjusted model." | 4.12 | Circulating short-chain fatty acids in type 2 diabetic patients and overweight/obese individuals. ( Annuzzi, G; Bozzetto, L; Corrado, A; Costabile, G; Della Pepa, G; Giacco, R; Luongo, D; Rivellese, AA; Salamone, D; Testa, R; Vitale, M, 2022) |
"Obesity is a multifaceted disease characterized by an abnormal accumulation of adipose tissue." | 3.30 | The effects of sodium butyrate supplementation on the expression levels of PGC-1α, PPARα, and UCP-1 genes, serum level of GLP-1, metabolic parameters, and anthropometric indices in obese individuals on weight loss diet: a study protocol for a triple-blind ( Amiri, P; Hosseini, SA; Roshanravan, N; Saghafi-Asl, M; Tootoonchian, M, 2023) |
"However, the role of butyrate in overnutrition-induced microglial activation and hypothalamic inflammation remains unclear." | 1.72 | Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation. ( Chen, T; Duan, C; Ge, X; Guo, K; Li, Y; Liu, H; Lu, H; Shang, Y; Wang, X; Zhang, D, 2022) |
"Obesity is a health concern." | 1.40 | Resistant starch from high amylose maize (HAM-RS2) and dietary butyrate reduce abdominal fat by a different apparent mechanism. ( Durham, HA; Finley, J; Gao, Z; Goldsmith, F; Greenway, F; Keenan, MJ; Martin, RJ; McCutcheon, KL; Pelkman, C; Raggio, AM; Senevirathne, RN; Vidrine, K; Williams, C; Ye, J; Zhou, J, 2014) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (2.78) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 19 (52.78) | 24.3611 |
2020's | 16 (44.44) | 2.80 |
Authors | Studies |
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Tang, X | 1 |
Sun, Y | 1 |
Li, Y | 3 |
Ma, S | 1 |
Zhang, K | 1 |
Chen, A | 1 |
Lyu, Y | 1 |
Yu, R | 1 |
Wang, X | 1 |
Duan, C | 1 |
Lu, H | 1 |
Guo, K | 1 |
Ge, X | 1 |
Chen, T | 1 |
Shang, Y | 1 |
Liu, H | 1 |
Zhang, D | 1 |
Salamone, D | 2 |
Costabile, G | 1 |
Corrado, A | 1 |
Della Pepa, G | 2 |
Vitale, M | 2 |
Giacco, R | 2 |
Luongo, D | 2 |
Testa, R | 1 |
Rivellese, AA | 2 |
Annuzzi, G | 1 |
Bozzetto, L | 1 |
Yu, HR | 1 |
Sheen, JM | 1 |
Hou, CY | 2 |
Lin, IC | 1 |
Huang, LT | 1 |
Tain, YL | 2 |
Cheng, HH | 1 |
Lai, YJ | 1 |
Lin, YJ | 1 |
Tiao, MM | 1 |
Tsai, CC | 1 |
Fu, Q | 1 |
Li, T | 1 |
Zhang, C | 2 |
Ma, X | 1 |
Meng, L | 1 |
Liu, L | 2 |
Shao, K | 1 |
Wu, G | 1 |
Zhu, X | 1 |
Zhao, X | 1 |
Liu, K | 1 |
He, X | 1 |
Huang, J | 1 |
Yu, S | 2 |
Cui, M | 1 |
Gao, M | 1 |
Qian, Y | 1 |
Xie, Y | 1 |
Hui, M | 1 |
Hong, Y | 1 |
Nie, X | 1 |
Zhang, L | 4 |
Chen, N | 1 |
Zhan, L | 1 |
Bi, T | 1 |
Zhou, W | 2 |
Zhu, L | 1 |
Chen, C | 1 |
Chen, W | 3 |
Ding, H | 1 |
Wu, P | 1 |
Zhang, G | 1 |
Xie, K | 1 |
Zhang, T | 1 |
Geng, N | 1 |
Zhang, Y | 3 |
Wang, H | 3 |
Song, J | 1 |
Yu, L | 1 |
Wu, C | 1 |
Amiri, P | 1 |
Hosseini, SA | 1 |
Roshanravan, N | 1 |
Saghafi-Asl, M | 1 |
Tootoonchian, M | 1 |
Celano, G | 1 |
Calabrese, FM | 1 |
Riezzo, G | 1 |
D'Attoma, B | 1 |
Ignazzi, A | 1 |
Di Chito, M | 1 |
Sila, A | 1 |
De Nucci, S | 1 |
Rinaldi, R | 1 |
Linsalata, M | 1 |
Vacca, M | 1 |
Apa, CA | 1 |
Angelis, M | 1 |
Giannelli, G | 1 |
De Pergola, G | 1 |
Russo, F | 1 |
Rad, ZA | 1 |
Mousavi, SN | 1 |
Chiti, H | 1 |
Oh, TJ | 1 |
Sul, WJ | 1 |
Oh, HN | 1 |
Lee, YK | 1 |
Lim, HL | 1 |
Choi, SH | 1 |
Park, KS | 1 |
Jang, HC | 1 |
Kim, SY | 1 |
Chae, CW | 1 |
Lee, HJ | 1 |
Jung, YH | 1 |
Choi, GE | 1 |
Kim, JS | 1 |
Lim, JR | 1 |
Lee, JE | 1 |
Cho, JH | 1 |
Park, H | 2 |
Park, C | 1 |
Han, HJ | 1 |
Laiola, M | 1 |
Mangione, A | 1 |
Vitaglione, P | 1 |
Ercolini, D | 1 |
Beisner, J | 1 |
Filipe Rosa, L | 1 |
Kaden-Volynets, V | 1 |
Stolzer, I | 1 |
Günther, C | 1 |
Bischoff, SC | 1 |
Shih, MK | 1 |
Chen, YW | 2 |
Hsu, WH | 1 |
Yeh, YT | 1 |
Chang, SKC | 1 |
Liao, JX | 1 |
Zhou, D | 1 |
Pan, Q | 1 |
Shen, F | 1 |
Cao, HX | 1 |
Ding, WJ | 1 |
Fan, JG | 1 |
Canfora, EE | 1 |
van der Beek, CM | 2 |
Jocken, JWE | 1 |
Goossens, GH | 2 |
Holst, JJ | 2 |
Olde Damink, SWM | 1 |
Lenaerts, K | 2 |
Dejong, CHC | 1 |
Blaak, EE | 2 |
Pelgrim, CE | 1 |
Franx, BAA | 1 |
Snabel, J | 1 |
Kleemann, R | 1 |
Arnoldussen, IAC | 1 |
Kiliaan, AJ | 1 |
Wu, T | 2 |
Guo, X | 2 |
Zhang, M | 2 |
Yang, L | 2 |
Liu, R | 2 |
Yin, J | 1 |
Aguilar, EC | 1 |
da Silva, JF | 1 |
Navia-Pelaez, JM | 1 |
Leonel, AJ | 1 |
Lopes, LG | 1 |
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Ferreira, AVM | 1 |
Capettini, LDSA | 1 |
Teixeira, LG | 1 |
Lemos, VS | 1 |
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Sui, W | 1 |
den Hartigh, LJ | 1 |
Gao, Z | 2 |
Goodspeed, L | 1 |
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Das, AK | 1 |
Burant, CF | 1 |
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Lindholm, MG | 1 |
Salazar, J | 1 |
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Añez, R | 1 |
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Kim, JU | 1 |
Lee, JW | 1 |
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Premasudha, P | 1 |
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Wang, B | 1 |
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Wang, D | 1 |
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Ferreira, IP | 1 |
Pinheiro, CB | 1 |
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Lohar, S | 1 |
Dhara, K | 1 |
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Sinha Babu, SP | 1 |
Chattopadhyay, P | 1 |
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Sunwoo, IY | 1 |
Lee, MJ | 1 |
Ra, CH | 1 |
Jeong, GT | 1 |
Kim, SK | 2 |
Huvinen, E | 1 |
Eriksson, JG | 1 |
Stach-Lempinen, B | 1 |
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Malhotra, M | 1 |
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Garg, A | 1 |
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Jiang, Y | 2 |
Liu, S | 1 |
Liu, Y | 1 |
Rausch-Fan, X | 1 |
Liu, Z | 1 |
Marques, WL | 1 |
van der Woude, LN | 1 |
Luttik, MAH | 1 |
van den Broek, M | 1 |
Nijenhuis, JM | 1 |
Pronk, JT | 1 |
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Pearce, CI | 1 |
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Lukens, WL | 1 |
Kim, DS | 1 |
Schweiger, MJ | 1 |
Kruger, AA | 1 |
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McDade, T | 1 |
Carba, DB | 1 |
Borja, JB | 1 |
Liang, X | 2 |
Song, W | 1 |
Wang, K | 1 |
Zhang, B | 1 |
Peele, ME | 1 |
Luo, HR | 1 |
Chen, ZY | 1 |
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Du, ZJ | 1 |
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Kim, DW | 1 |
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Li, B | 2 |
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Kim, BS | 1 |
Kim, JJ | 1 |
Wang, JJ | 1 |
Chen, Q | 1 |
Li, YZ | 1 |
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Yamaguchi, M | 1 |
Nagao, Y | 1 |
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Watanabe, S | 1 |
Takahashi, T | 1 |
Arakawa, K | 1 |
Nakano, T | 1 |
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Plass, F | 1 |
Planchat, A | 1 |
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Angaridis, PA | 1 |
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Ling, W | 1 |
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Ye, J | 2 |
Martin, RJ | 1 |
McCutcheon, KL | 1 |
Raggio, AM | 1 |
Pelkman, C | 1 |
Durham, HA | 1 |
Zhou, J | 1 |
Senevirathne, RN | 1 |
Williams, C | 1 |
Greenway, F | 1 |
Finley, J | 1 |
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Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
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The Role of Microbiome Reprogramming on Liver Fat Accumulation[NCT03914495] | 57 participants (Actual) | Interventional | 2019-05-21 | Terminated (stopped due to PI carefully considered multiple factors and decided to close study to any further enrollment.) | |||
Using a Complex Carbohydrate Mixture Added to a High-protein Diet to Steer Fermentation and Improve Metabolic, Gut and Brain Health[NCT05354245] | 44 participants (Anticipated) | Interventional | 2022-09-08 | Recruiting | |||
Acceptability, Tolerance, Satiety and Prebiotic Effect of a New Infant Cereal in Infant Between 5 and 8 Months of Age, at the Beginning of Complementary Feeding[NCT02781298] | 46 participants (Actual) | Interventional | 2014-12-31 | Completed | |||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
2 reviews available for butyric acid and Obesity
Article | Year |
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New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
Topics: Anticarcinogenic Agents; Antioxidants; Blood Glucose; Butyric Acid; Cardiovascular Diseases; Diabete | 2010 |
Butyric acid: what is the future for this old substance?
Topics: beta-Thalassemia; Butyric Acid; Humans; Inflammatory Bowel Diseases; Intestinal Mucosa; Intestines; | 2012 |
5 trials available for butyric acid and Obesity
Article | Year |
---|---|
The effects of sodium butyrate supplementation on the expression levels of PGC-1α, PPARα, and UCP-1 genes, serum level of GLP-1, metabolic parameters, and anthropometric indices in obese individuals on weight loss diet: a study protocol for a triple-blind
Topics: Adolescent; Adult; Butyric Acid; Diet, Reducing; Dietary Supplements; Glucagon-Like Peptide 1; Human | 2023 |
Acute and chronic improvement in postprandial glucose metabolism by a diet resembling the traditional Mediterranean dietary pattern: Can SCFAs play a role?
Topics: Adult; Area Under Curve; Blood Glucose; Butyric Acid; Diet, Mediterranean; Diet, Western; Fasting; F | 2021 |
Colonic infusions of short-chain fatty acid mixtures promote energy metabolism in overweight/obese men: a randomized crossover trial.
Topics: Acetic Acid; Adult; Butyric Acid; Colon; Cross-Over Studies; Double-Blind Method; Energy Metabolism; | 2017 |
Topics: Activities of Daily Living; Acute Disease; Adalimumab; Adaptation, Physiological; Adenosine Triphosp | 2018 |
Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial.
Topics: Adipocytes; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Biomarkers; Butyric Acid; Cell Shape; D | 2016 |
29 other studies available for butyric acid and Obesity
Article | Year |
---|---|
Sodium butyrate protects against oxidative stress in high-fat-diet-induced obese rats by promoting GSK-3β/Nrf2 signaling pathway and mitochondrial function.
Topics: Animals; Antioxidants; Body Weight; Butyric Acid; Diet, High-Fat; Dietary Fiber; Glucose; Glutathion | 2022 |
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
Topics: Animals; Butyric Acid; Diet, High-Fat; Hypothalamus; Inflammation; Mice; Mice, Inbred C57BL; Microgl | 2022 |
Circulating short-chain fatty acids in type 2 diabetic patients and overweight/obese individuals.
Topics: Acetic Acid; Butyric Acid; Diabetes Mellitus, Type 2; Fatty Acids, Volatile; Humans; Obesity; Overwe | 2022 |
Effects of Maternal Gut Microbiota-Targeted Therapy on the Programming of Nonalcoholic Fatty Liver Disease in Dams and Fetuses, Related to a Prenatal High-Fat Diet.
Topics: Animals; Butyric Acid; Diet, High-Fat; Fatty Acids, Volatile; Female; Fetus; Gastrointestinal Microb | 2022 |
Butyrate mitigates metabolic dysfunctions via the ERα-AMPK pathway in muscle in OVX mice with diet-induced obesity.
Topics: AMP-Activated Protein Kinases; Animals; Butyric Acid; Diet, High-Fat; Estrogen Receptor alpha; Femal | 2023 |
Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome.
Topics: Animals; Butyric Acid; DNA Methylation; Fatty Acids, Volatile; Female; Fos-Related Antigen-2; Granul | 2023 |
Erchen Decoction alleviates obesity-related hepatic steatosis via modulating gut microbiota-drived butyric acid contents and promoting fatty acid β-oxidation.
Topics: Animals; Butyric Acid; Diet, High-Fat; Fatty Acids, Volatile; Gastrointestinal Microbiome; Mice; Mic | 2023 |
High-fat diet-induced gut microbiota alteration promotes lipogenesis by butyric acid/miR-204/ACSS2 axis in chickens.
Topics: Animals; Butyric Acid; Chickens; Diet, High-Fat; Dysbiosis; Gastrointestinal Microbiome; Lipogenesis | 2023 |
Effects of Modified Dietary Fiber from Fresh Corn Bracts on Obesity and Intestinal Microbiota in High-Fat-Diet Mice.
Topics: Animals; Butyric Acid; Diet, High-Fat; Dietary Fiber; Gastrointestinal Microbiome; Mice; Mice, Inbre | 2023 |
Effects of a Very-Low-Calorie Ketogenic Diet on the Fecal and Urinary Volatilome in an Obese Patient Cohort: A Preliminary Investigation.
Topics: Butyric Acid; Diet, Ketogenic; Esters; Humans; Obesity; Pilot Projects; Volatile Organic Compounds | 2023 |
A low-carb diet increases fecal short-chain fatty acids in feces of obese women following a weight-loss program: randomized feeding trial.
Topics: Acetic Acid; Butyric Acid; Diet; Fatty Acids, Volatile; Feces; Female; Humans; Insulins; Interleukin | 2023 |
Butyrate attenuated fat gain through gut microbiota modulation in db/db mice following dapagliflozin treatment.
Topics: Adipose Tissue; Animals; Benzhydryl Compounds; Butyric Acid; Disease Models, Animal; Gastrointestina | 2019 |
Sodium butyrate inhibits high cholesterol-induced neuronal amyloidogenesis by modulating NRF2 stabilization-mediated ROS levels: involvement of NOX2 and SOD1.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Butyric Acid; Humans; Mice; NADPH Oxidase 2; NF-E | 2020 |
Prebiotic Inulin and Sodium Butyrate Attenuate Obesity-Induced Intestinal Barrier Dysfunction by Induction of Antimicrobial Peptides.
Topics: Animal Feed; Animals; Biomarkers; Butyric Acid; Dietary Supplements; Disease Models, Animal; Female; | 2021 |
Resveratrol Butyrate Esters Inhibit Obesity Caused by Perinatal Exposure to Bisphenol A in Female Offspring Rats.
Topics: Animals; Benzhydryl Compounds; Butyric Acid; Fatty Acids, Volatile; Female; Gastrointestinal Microbi | 2021 |
Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota.
Topics: Adipose Tissue; Animals; Body Weight; Butyric Acid; Cecum; Diet, High-Fat; Endotoxemia; Epididymis; | 2017 |
Butyrate Reduces HFD-Induced Adipocyte Hypertrophy and Metabolic Risk Factors in Obese LDLr-/-.Leiden Mice.
Topics: Adipocytes; Adipokines; Adipose Tissue; Animals; Butyric Acid; Cell Size; Diabetes Mellitus, Type 2; | 2017 |
Anthocyanins in black rice, soybean and purple corn increase fecal butyric acid and prevent liver inflammation in high fat diet-induced obese mice.
Topics: Animals; Anthocyanins; Butyric Acid; Diet, High-Fat; Feces; Glycine max; Humans; Interleukin-6; Live | 2017 |
Sodium butyrate modulates adipocyte expansion, adipogenesis, and insulin receptor signaling by upregulation of PPAR-γ in obese Apo E knockout mice.
Topics: Adipocytes; Adipogenesis; Animals; Anti-Obesity Agents; Butyric Acid; Dietary Supplements; Mice; Mic | 2018 |
Raspberry anthocyanin consumption prevents diet-induced obesity by alleviating oxidative stress and modulating hepatic lipid metabolism.
Topics: Animals; Anthocyanins; Anti-Obesity Agents; Antioxidants; Biomarkers; Butyric Acid; Diet, High-Fat; | 2018 |
Obese Mice Losing Weight Due to trans-10,cis-12 Conjugated Linoleic Acid Supplementation or Food Restriction Harbor Distinct Gut Microbiota.
Topics: Acetic Acid; Animals; Bacteria; Butyric Acid; Caloric Restriction; Colon; Diet, High-Fat; Diet, Redu | 2018 |
Effects of oral butyrate supplementation on inflammatory potential of circulating peripheral blood mononuclear cells in healthy and obese males.
Topics: Adult; Anti-Infective Agents; BCG Vaccine; beta-Glucans; Butyric Acid; Case-Control Studies; Cytokin | 2019 |
Supplementation with Sodium Butyrate Modulates the Composition of the Gut Microbiota and Ameliorates High-Fat Diet-Induced Obesity in Mice.
Topics: Animals; Butyric Acid; Colon; Diet, High-Fat; Dietary Fats; Dietary Supplements; Dysbiosis; Gastroin | 2019 |
Resistant starch from high amylose maize (HAM-RS2) and dietary butyrate reduce abdominal fat by a different apparent mechanism.
Topics: Abdominal Fat; Adiposity; Amylose; Animals; Anti-Obesity Agents; Bifidobacterium; Butyric Acid; Cecu | 2014 |
Sodium butyrate epigenetically modulates high-fat diet-induced skeletal muscle mitochondrial adaptation, obesity and insulin resistance through nucleosome positioning.
Topics: Adaptation, Physiological; Adiposity; Animals; Blood Glucose; Body Weight; Butyric Acid; Carnitine; | 2015 |
Increased Butyrate Production During Long-Term Fermentation of In Vitro-Digested High Amylose Cornstarch Residues with Human Feces.
Topics: Adult; Amylose; Bacteria; Body Mass Index; Butyric Acid; Diet; Dietary Carbohydrates; Digestion; Fat | 2015 |
Sodium Butyrate Protects -Against High Fat Diet-Induced Cardiac Dysfunction and Metabolic Disorders in Type II Diabetic Mice.
Topics: Animals; Butyric Acid; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 2; Diet, High-Fat; E | 2017 |
Burdock fermented by Aspergillus awamori elevates cecal Bifidobacterium, and reduces fecal deoxycholic acid and adipose tissue weight in rats fed a high-fat diet.
Topics: Acetic Acid; Adipose Tissue; Animals; Arctium; Aspergillus; Bifidobacterium; Butyric Acid; Cecum; De | 2013 |
Urinary organic acid profiles in fatty Zucker rats: indications for impaired oxidation of butyrate and hexanoate.
Topics: Acids; Acyl-CoA Dehydrogenase; Animals; Butyrates; Butyric Acid; Caproates; Fatty Acid Desaturases; | 1990 |