butyric acid has been researched along with Neoplasms in 16 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome." | 4.80 | Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000) |
| "Cancer cachexia is mainly characterized by wasting of skeletal muscles and fat and body weight loss, along with severe complications of major organs like liver, heart, brain and bone." | 1.72 | Systemic study of selected histone deacetylase inhibitors in cardiac complications associated with cancer cachexia. ( Bora, V; Goyal, RK; Johar, K; Patel, BM; Patel, D, 2022) |
| "Butyrate exerts its anti-cancerous effects by several mechanisms and has lead to successful outcomes in phase I and II clinical trials." | 1.39 | Efficient tumor targeting by anaerobic butyrate-producing bacteria. ( Mohammadi, E; Tirandaz, H, 2013) |
| "Both BuNa and VaNa inhibited cancer cell proliferation in a time--and dose-dependent fashion." | 1.38 | [Possibilities of epigenetic anti-tumor therapy in in-vitro models]. ( Bondarev, GN; Filatov, MV; Ibatulin, FM; Kovalëv, RA; Stam, TA, 2012) |
| "For cell lines and some NaBu-treated tumors we found histone H4 hyperacetylation." | 1.33 | Effect of sodium butyrate on pro-matrix metalloproteinase-9 and -2 differential secretion in pediatric tumors and cell lines. ( Arenas-Huertero, F; Armas-Pineda, C; Chico-Ponce de León, F; Lezama, P; Perezpeña-Diazconti, M; Recillas-Targa, F; Rodríguez-Salvador, J; Sosa-Sáinz, G, 2005) |
| "The anticancer activity of the prodrugs in vitro was evaluated by examining their effect on the growth of human colon, breast and pancreatic carcinoma cell lines, and their solubility in aqueous media was determined." | 1.31 | Prodrugs of butyric acid. Novel derivatives possessing increased aqueous solubility and potential for treating cancer and blood diseases. ( Azulai, R; Cohen-Ohana, M; Fibach, E; Gnizi, E; Katz, Y; Langzam, L; Nudelman, A; Prus, E; Pugach, V; Rephaeli, A; Sampson, SR; Zhuk, R, 2001) |
| "3." | 1.29 | n-Butyrate mediation of ganglioside expression of human and murine cancer cells demonstrates relative cell specificity. ( Berenson, CS; Lance, P; Miqdadi, JA; Patterson, MA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (25.00) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 5 (31.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Tukey, RH | 1 |
| Strassburg, CP | 1 |
| Bora, V | 1 |
| Patel, D | 1 |
| Johar, K | 1 |
| Goyal, RK | 1 |
| Patel, BM | 1 |
| Bowen, JM | 1 |
| Gibson, RJ | 1 |
| Coller, JK | 1 |
| Blijlevens, N | 1 |
| Bossi, P | 1 |
| Al-Dasooqi, N | 1 |
| Bateman, EH | 1 |
| Chiang, K | 1 |
| de Mooij, C | 1 |
| Mayo, B | 1 |
| Stringer, AM | 1 |
| Tissing, W | 1 |
| Wardill, HR | 1 |
| van Sebille, YZA | 1 |
| Ranna, V | 1 |
| Vaddi, A | 1 |
| Keefe, DM | 1 |
| Lalla, RV | 1 |
| Cheng, KKF | 1 |
| Elad, S | 1 |
| Tirandaz, H | 1 |
| Mohammadi, E | 1 |
| Kovalëv, RA | 1 |
| Stam, TA | 1 |
| Ibatulin, FM | 1 |
| Bondarev, GN | 1 |
| Filatov, MV | 1 |
| Fardet, A | 1 |
| WATSON, J | 1 |
| Heidor, R | 1 |
| Ortega, JF | 1 |
| de Conti, A | 1 |
| Ong, TP | 1 |
| Moreno, FS | 1 |
| CZIHARZ, H | 1 |
| BRUCKER, W | 1 |
| Rodríguez-Salvador, J | 1 |
| Armas-Pineda, C | 1 |
| Perezpeña-Diazconti, M | 1 |
| Chico-Ponce de León, F | 1 |
| Sosa-Sáinz, G | 1 |
| Lezama, P | 1 |
| Recillas-Targa, F | 1 |
| Arenas-Huertero, F | 1 |
| Berenson, CS | 1 |
| Patterson, MA | 1 |
| Miqdadi, JA | 1 |
| Lance, P | 1 |
| Ghibelli, L | 1 |
| Coppola, S | 1 |
| Nosseri, C | 1 |
| Bergamini, A | 1 |
| Beninati, S | 1 |
| Goh, SH | 1 |
| Hew, NF | 1 |
| Norhanom, AW | 1 |
| Yadav, M | 1 |
| Nudelman, A | 1 |
| Gnizi, E | 1 |
| Katz, Y | 1 |
| Azulai, R | 1 |
| Cohen-Ohana, M | 1 |
| Zhuk, R | 1 |
| Sampson, SR | 1 |
| Langzam, L | 1 |
| Fibach, E | 1 |
| Prus, E | 1 |
| Pugach, V | 1 |
| Rephaeli, A | 1 |
| Fujiwara, Y | 1 |
| Matsumoto, A | 1 |
| Ichihashi, M | 1 |
| Satoh, Y | 1 |
| Newman, RA | 1 |
| Bauer, DM | 1 |
| Zuckerman, JE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acceptability, Tolerance, Satiety and Prebiotic Effect of a New Infant Cereal in Infant Between 5 and 8 Months of Age, at the Beginning of Complementary Feeding[NCT02781298] | 46 participants (Actual) | Interventional | 2014-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for butyric acid and Neoplasms
| Article | Year |
|---|---|
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; | 2000 |
Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines.
Topics: Butyric Acid; Chemoradiotherapy; Fibroblast Growth Factor 7; Glutamine; Humans; Hyperbaric Oxygenati | 2019 |
New hypotheses for the health-protective mechanisms of whole-grain cereals: what is beyond fibre?
Topics: Anticarcinogenic Agents; Antioxidants; Blood Glucose; Butyric Acid; Cardiovascular Diseases; Diabete | 2010 |
Anticarcinogenic actions of tributyrin, a butyric acid prodrug.
Topics: Animals; Anticarcinogenic Agents; Butyric Acid; Cell Line, Tumor; Humans; Neoplasms; Prodrugs; Trigl | 2012 |
12 other studies available for butyric acid and Neoplasms
| Article | Year |
|---|---|
Systemic study of selected histone deacetylase inhibitors in cardiac complications associated with cancer cachexia.
Topics: Animals; Benzamides; Butyric Acid; Cachexia; Cell Line, Tumor; Disease Models, Animal; Disease Progr | 2022 |
Efficient tumor targeting by anaerobic butyrate-producing bacteria.
Topics: Bacteria, Anaerobic; Biological Products; Butyric Acid; Humans; Neoplasms | 2013 |
[Possibilities of epigenetic anti-tumor therapy in in-vitro models].
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butyric Acid; Cell | 2012 |
A chemical test for the presence of cancer; its early detection and destruction by the selective action of bromo- and chloro-butyrates.
Topics: Butyrates; Butyric Acid; Early Diagnosis; Humans; Neoplasms | 1946 |
[On the influence of kinetin and indolyl-3-butyric acid on the callus and crown-gall tissue of Datura and Daucus in vitro].
Topics: Alkaloids; Butyric Acid; Crowns; Datura; Datura stramonium; Growth Substances; In Vitro Techniques; | 1962 |
Effect of sodium butyrate on pro-matrix metalloproteinase-9 and -2 differential secretion in pediatric tumors and cell lines.
Topics: Acetylation; Butyric Acid; Cell Line, Tumor; Child; Electrophoresis, Polyacrylamide Gel; Enzyme Prec | 2005 |
n-Butyrate mediation of ganglioside expression of human and murine cancer cells demonstrates relative cell specificity.
Topics: Animals; Butyrates; Butyric Acid; Cell Line; Chromatography, Thin Layer; Colonic Neoplasms; Dose-Res | 1995 |
A protein produced by a monocytic human cell line can induce apoptosis on tumor cells.
Topics: Apoptosis; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Culture Media, Conditioned; Cyt | 1994 |
Inhibition of tumour promotion by various palm-oil tocotrienols.
Topics: Anticarcinogenic Agents; Antigens, Viral; Butyrates; Butyric Acid; Cell Transformation, Viral; Genom | 1994 |
Prodrugs of butyric acid. Novel derivatives possessing increased aqueous solubility and potential for treating cancer and blood diseases.
Topics: Animals; Apoptosis; Butyric Acid; Cell Division; Female; Hemoglobins; HL-60 Cells; Humans; Lethal Do | 2001 |
Heritable disorders of DNA repair: xeroderma pigmentosum and Fanconi's anemia.
Topics: Alleles; Anemia, Aplastic; Butyrates; Butyric Acid; Cell-Free System; Cross-Linking Reagents; DNA; D | 1987 |
Sodium n-butyrate enhancement of prostaglandin D2 antitumor efficacy.
Topics: Antineoplastic Agents; Butyrates; Butyric Acid; Cell Line; Cell Survival; Drug Evaluation; Drug Syne | 1985 |