Page last updated: 2024-10-16

butyric acid and Melanoma

butyric acid has been researched along with Melanoma in 16 studies

Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.

Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

Research Excerpts

ExcerptRelevanceReference
"Treatment of B16-F10 melanoma cells with dimethylsulfoxide (DMSO) or butyric acid (BA) inhibits cell growth and delays tumor appearance in syngeneic mice."7.67Growth inhibition of murine melanoma by butyric acid and dimethylsulfoxide. ( Aloni, D; Beery, E; Malik, H; Nordenberg, J; Novogrodsky, A; Stenzel, KH; Wasserman, L, 1986)
"Sodium butyrate (butyrate), 5-azacytidine (5Aza-C), dimethyl sulfoxide (DMSO), and dimethyl formamide (DMF) were applied to a human melanoma cell line for the purpose of inducing pigmentation and terminal differentiation."3.68In vitro phenotypic alteration of human melanoma cells induced by differentiating agents: heterogeneous effects on cellular growth and morphology, enzymatic activity, and antigenic expression. ( Parsons, PG; Takahashi, H, 1990)
"Treatment of B16-F10 melanoma cells with dimethylsulfoxide (DMSO) or butyric acid (BA) inhibits cell growth and delays tumor appearance in syngeneic mice."3.67Growth inhibition of murine melanoma by butyric acid and dimethylsulfoxide. ( Aloni, D; Beery, E; Malik, H; Nordenberg, J; Novogrodsky, A; Stenzel, KH; Wasserman, L, 1986)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19906 (37.50)18.7374
1990's6 (37.50)18.2507
2000's2 (12.50)29.6817
2010's1 (6.25)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Shashni, B1
Nagasaki, Y1
Lakhter, AJ1
Hamilton, J1
Konger, RL1
Brustovetsky, N1
Broxmeyer, HE1
Naidu, SR1
Bandyopadhyay, D1
Mishra, A1
Medrano, EE1
Ichikawa, N1
Miyashita, T1
Nishimune, Y1
Matsushiro, A1
Linge, C1
Gewert, D1
Rossmann, C1
Bishop, JA1
Crowe, JS1
Wu, QH1
Trymbulak, W1
Tatake, RJ1
Forman, SJ1
Zeff, RA1
Shanley, JD1
Zhai, Y1
Yang, JC1
Kawakami, Y1
Spiess, P1
Wadsworth, SC1
Cardoza, LM1
Couture, LA1
Smith, AE1
Rosenberg, SA1
Edward, M1
Godden, JL1
Alexander, CL1
MacKie, RM1
Salomone, B1
Ponti, R1
Gasco, MR1
Ugazio, E1
Quaglino, P1
Osella-Abate, S1
Bernengo, MG1
Takahashi, H2
Parsons, PG2
Sturm, RA1
Bisshop, F1
Nordenberg, J3
Wasserman, L2
Peled, A2
Malik, Z1
Stenzel, KH2
Novogrodsky, A3
Niles, RM1
Beery, E1
Aloni, D1
Malik, H1
Adler, A1
Nozawa, S1
Tsai, DZ1
Sakayori, M1
Iizuka, R1
Nishimura, R1
Mochizuki, M1

Reviews

1 review available for butyric acid and Melanoma

ArticleYear
Chemical induction of tumor cell differentiation.
    Survey and synthesis of pathology research, 1985, Volume: 4, Issue:4

    Topics: Animals; Butyrates; Butyric Acid; Cell Division; Cell Line; Cell Transformation, Neoplastic; Choleca

1985

Other Studies

15 other studies available for butyric acid and Melanoma

ArticleYear
Short-chain fatty acid-releasing nano-prodrugs for attenuating growth and metastasis of melanoma.
    Acta biomaterialia, 2023, 03-15, Volume: 159

    Topics: Animals; Butyric Acid; Fatty Acids, Volatile; Melanoma; Mice

2023
Glucose-independent Acetate Metabolism Promotes Melanoma Cell Survival and Tumor Growth.
    The Journal of biological chemistry, 2016, Oct-14, Volume: 291, Issue:42

    Topics: Acetates; Acetyl-CoA Carboxylase; Adenosine Triphosphate; Animals; Butyric Acid; Cell Line, Tumor; F

2016
Overexpression of histone deacetylase 1 confers resistance to sodium butyrate-mediated apoptosis in melanoma cells through a p53-mediated pathway.
    Cancer research, 2004, Nov-01, Volume: 64, Issue:21

    Topics: Apoptosis; bcl-2-Associated X Protein; Butyric Acid; Cell Line, Tumor; Histone Deacetylase 1; Histon

2004
Production, purification and characterization of the plasminogen activator in teratocarcinoma stem cells induced with sodium butyrate.
    Biken journal, 1984, Volume: 27, Issue:4

    Topics: Animals; Butyrates; Butyric Acid; Cell Line; Cell Transformation, Neoplastic; Electrophoresis, Polya

1984
Interferon system defects in human malignant melanoma.
    Cancer research, 1995, Sep-15, Volume: 55, Issue:18

    Topics: Base Sequence; Butyrates; Butyric Acid; Genes, Tumor Suppressor; Humans; Interferon-alpha; Interfero

1995
Replication of human cytomegalovirus in cells deficient in beta 2-microglobulin gene expression.
    The Journal of general virology, 1994, Volume: 75 ( Pt 10)

    Topics: Animals; beta 2-Microglobulin; Butyrates; Butyric Acid; Cell Line; Cells, Cultured; Cytomegalovirus;

1994
Antigen-specific tumor vaccines. Development and characterization of recombinant adenoviruses encoding MART1 or gp100 for cancer therapy.
    Journal of immunology (Baltimore, Md. : 1950), 1996, Jan-15, Volume: 156, Issue:2

    Topics: Adenoviridae; Adenovirus E3 Proteins; Animals; Antigens, Neoplasm; Butyrates; Butyric Acid; Cell Lin

1996
Effect of retinoic acid on melanoma cell-derived factor stimulation of fibroblast glycosaminoglycan synthesis.
    Melanoma research, 1997, Volume: 7, Issue:3

    Topics: Acetamides; Adult; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Count; Cell Differentiation;

1997
In vitro effects of cholesteryl butyrate solid lipid nanospheres as a butyric acid pro-drug on melanoma cells: evaluation of antiproliferative activity and apoptosis induction.
    Clinical & experimental metastasis, 2000, Volume: 18, Issue:8

    Topics: Annexin A5; Apoptosis; Butyric Acid; Cell Division; Cholesterol Esters; Dose-Response Relationship,

2000
In vitro phenotypic alteration of human melanoma cells induced by differentiating agents: heterogeneous effects on cellular growth and morphology, enzymatic activity, and antigenic expression.
    Pigment cell research, 1990, Volume: 3, Issue:5

    Topics: Antigens, Neoplasm; Azacitidine; Butyrates; Butyric Acid; Cell Cycle; Cell Differentiation; Cell Div

1990
A melanoma octamer binding protein is responsive to differentiating agents.
    Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research, 1991, Volume: 2, Issue:10

    Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line, Transformed; Dimethyl Sulfoxide; Dithiothr

1991
Biochemical and ultrastructural alterations accompany the anti-proliferative effect of butyrate on melanoma cells.
    British journal of cancer, 1987, Volume: 55, Issue:5

    Topics: Animals; Butyrates; Butyric Acid; Cell Line; Clone Cells; Endoplasmic Reticulum; gamma-Glutamyltrans

1987
Growth inhibition of murine melanoma by butyric acid and dimethylsulfoxide.
    Experimental cell research, 1986, Volume: 162, Issue:1

    Topics: Animals; Butyrates; Butyric Acid; Cell Division; Cell Line; Cell Survival; Dimethyl Sulfoxide; Melan

1986
[Inhibition of growth of human melanoma cells and enhancement of alkaline phosphatase activity by butyric acid].
    Harefuah, 1986, Volume: 111, Issue:1-2

    Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; GPI-Linked Proteins;

1986
HCG production of non-trophoblastic cancer cell lines and its modulation by sodium butyrate.
    Nihon Sanka Fujinka Gakkai zasshi, 1985, Volume: 37, Issue:9

    Topics: Adenocarcinoma; Butyrates; Butyric Acid; Carcinoma, Squamous Cell; Cell Line; Chorionic Gonadotropin

1985