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butyric acid and Lung Neoplasms

butyric acid has been researched along with Lung Neoplasms in 24 studies

Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.

Lung Neoplasms: Tumors or cancer of the LUNG.

Research Excerpts

ExcerptRelevanceReference
"We developed a mitomycin C (MMC)-resistant human lung adenocarcinoma cell subline, SPC-A1/DM4, from cloned SPC-A1/D13 parent cells by 1 h exposures to escalating concentrations of the drug over 17 months."7.68Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. ( Dong, QG; Gong, LL; Wang, EZ; Wang, HJ, 1993)
" We found that polar compounds and butyric acid, which are known to alter the expressions of normally silent genes, enhanced the lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells."4.77Modification of the metastatic potential of tumor cells by drugs. ( Takenaga, K, 1986)
"A low concentration of differentiation inducers such as dimethylsulphoxide (DMSO), sodium butyrate, hexamethylene bisacetamide and sodium phenylacetate greatly enhanced the antiproliferative effect in vitro and in vivo of interferon alpha (IFN-alpha) to several human lung adenocarcinoma cells."3.69Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents. ( Goto, I; Honma, Y; Yamamoto-Yamaguchi, Y, 1996)
"We developed a mitomycin C (MMC)-resistant human lung adenocarcinoma cell subline, SPC-A1/DM4, from cloned SPC-A1/D13 parent cells by 1 h exposures to escalating concentrations of the drug over 17 months."3.68Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. ( Dong, QG; Gong, LL; Wang, EZ; Wang, HJ, 1993)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-19905 (20.83)18.7374
1990's9 (37.50)18.2507
2000's2 (8.33)29.6817
2010's6 (25.00)24.3611
2020's2 (8.33)2.80

Authors

AuthorsStudies
Cristiano, C1
Cuozzo, M1
Coretti, L1
Liguori, FM1
Cimmino, F1
Turco, L1
Avagliano, C1
Aviello, G1
Mollica, MP1
Lembo, F1
Russo, R1
Xiao, X2
Xu, Y1
Chen, H1
Zhao, L1
Bin, S1
He, HL1
Yang, JM1
Pu, YC1
Gao, CH1
Wang, H1
Wang, BL1
Chen, CQ1
Chen, CS1
Chen, JJ1
Zhou, LP1
Xu, HL1
Jin, WW1
Wu, JB1
Gao, SM1
Jin, X1
Wu, N1
Dai, J1
Li, Q1
Hichino, A1
Okamoto, M1
Taga, S1
Akizuki, R1
Endo, S1
Matsunaga, T1
Ikari, A1
Guo, R1
Zhang, Y1
Liang, S1
Xu, H1
Zhang, M1
Li, B1
Edmond, V1
Brambilla, C1
Brambilla, E1
Gazzeri, S1
Eymin, B1
Sonnemann, J1
Gänge, J1
Kumar, KS1
Müller, C1
Bader, P1
Beck, JF1
Bártová, E1
Pacherník, J1
Harnicarová, A1
Kovarík, A1
Kovaríková, M1
Hofmanová, J1
Skalníková, M1
Kozubek, M1
Kozubek, S1
Ghosh, NK1
Tang, DC1
Johnston, SA1
Carbone, DP1
Chen, Z1
Ke, Y1
Chen, Y1
Dong, QG1
Gong, LL1
Wang, HJ1
Wang, EZ1
Khan, MZ1
Freshney, RI1
McNicol, AM1
Murray, AM1
Goto, I1
Yamamoto-Yamaguchi, Y1
Honma, Y1
Nakai, T2
Ishima, R1
Sakahara, H2
Endo, K2
Konishi, J1
Akasaka, K1
Hay, FG1
Duncan, LW1
Langdon, SP1
Leonard, RC1
Hosono, M1
Saga, T1
Watanabe, Y1
Imai, K1
Yachi, A1
Kiyozuka, Y1
Ishiwata, I1
Rephaeli, A1
Rabizadeh, E1
Aviram, A1
Shaklai, M1
Ruse, M1
Nudelman, A1
Nagelberg, SB1
Burnside, J1
Maniatis, A1
Lippman, SS1
Weintraub, BD1
Takenaga, K3
Nakamura, Y1
Sakiyama, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Study on Fluids Associated to Lung Cancer, of the Ectopic Expression of Cancer Testis Gene and Mutation as Diagnostics and Prognosis Biomarkers[NCT02853006]31 participants (Actual)Interventional2015-06-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for butyric acid and Lung Neoplasms

ArticleYear
Histone deacetylase inhibitors interact synergistically with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis in carcinoma cell lines.
    Investigational new drugs, 2005, Volume: 23, Issue:2

    Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Butyric Acid; Caspase 3; Caspases;

2005
Modification of the metastatic potential of tumor cells by drugs.
    Cancer metastasis reviews, 1986, Volume: 5, Issue:2

    Topics: Animals; Azacitidine; Butyrates; Butyric Acid; Carcinoma; Cell Division; Cell Line; Cells, Cultured;

1986

Other Studies

22 other studies available for butyric acid and Lung Neoplasms

ArticleYear
Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 153

    Topics: Animals; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Dietary Supplements; Gastrointestinal Microbi

2022
Sodium butyrate-activated TRAF6-TXNIP pathway affects A549 cells proliferation and migration.
    Cancer medicine, 2020, Volume: 9, Issue:10

    Topics: A549 Cells; Animals; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Movement;

2020
Sodium butyrate increases P-gp expression in lung cancer by upregulation of STAT3 and mRNA stabilization of ABCB1.
    Anti-cancer drugs, 2018, Volume: 29, Issue:3

    Topics: A549 Cells; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfami

2018
Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer.
    Molecular and cellular biochemistry, 2013, Volume: 383, Issue:1-2

    Topics: Acetylation; Apoptosis; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell L

2013
TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4-phenylbutyrate treatment.
    Cancer medicine, 2017, Volume: 6, Issue:2

    Topics: A549 Cells; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Caspase 3; Caspase 7; Ce

2017
Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells.
    The Journal of biological chemistry, 2017, 02-10, Volume: 292, Issue:6

    Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Azacitidine; Butyric Acid; Cell Proliferation; C

2017
Sodium butyrate enhances the expression of baculovirus-mediated sodium/iodide symporter gene in A549 lung adenocarcinoma cells.
    Nuclear medicine communications, 2010, Volume: 31, Issue:10

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Baculoviridae; Biological Transport; Blotting, Western; Buty

2010
SRSF2 is required for sodium butyrate-mediated p21(WAF1) induction and premature senescence in human lung carcinoma cell lines.
    Cell cycle (Georgetown, Tex.), 2011, Jun-15, Volume: 10, Issue:12

    Topics: Butyric Acid; Cell Line, Tumor; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Histone

2011
Nuclear levels and patterns of histone H3 modification and HP1 proteins after inhibition of histone deacetylases.
    Journal of cell science, 2005, Nov-01, Volume: 118, Issue:Pt 21

    Topics: Apoptosis; Butyric Acid; Carcinoma, Small Cell; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Nucleu

2005
Drug-induced biochemical markers of cancer in cervical carcinoma cells.
    Clinical biochemistry, 1982, Volume: 15, Issue:1

    Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Chorionic Gonadotropin; Cho

1982
Butyrate-inducible and tumor-restricted gene expression by adenovirus vectors.
    Cancer gene therapy, 1994, Volume: 1, Issue:1

    Topics: Adenoviruses, Human; Animals; beta-Galactosidase; Butyrates; Butyric Acid; Carcinoma; Cytomegaloviru

1994
A serum-free medium for hybridoma cell culture.
    Cytotechnology, 1993, Volume: 11, Issue:3

    Topics: Animals; Antibodies, Monoclonal; Butyrates; Butyric Acid; Carcinoma, Small Cell; Cell Division; Cult

1993
Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance.
    Anti-cancer drugs, 1993, Volume: 4, Issue:6

    Topics: Adenocarcinoma; Butyrates; Butyric Acid; Cell Division; Cell Survival; Cisplatin; DNA, Neoplasm; Dru

1993
Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1993, Volume: 4, Issue:6

    Topics: Acetamides; Animals; Antineoplastic Agents; Biomarkers, Tumor; Butyrates; Butyric Acid; Carcinoma, S

1993
Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents.
    British journal of cancer, 1996, Volume: 74, Issue:4

    Topics: Acetamides; Adenocarcinoma; Alkaline Phosphatase; Animals; Antineoplastic Agents; Biomarkers; Butyra

1996
1H-magnetic resonance spectroscopic observation of cultured malignant cells pharmacologically induced to different phenotypes.
    Academic radiology, 1996, Volume: 3, Issue:9

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Butyrates; Butyric Acid; Cho

1996
Modulation of the cluster 1 and mucin antigens in human small cell lung cancer and other epithelial tumour cell lines after treatment with the differentiation inducing agent, sodium butyrate.
    The British journal of cancer. Supplement, 1991, Volume: 14

    Topics: Adenocarcinoma; Alkaline Phosphatase; Antibodies, Monoclonal; Antigens, Neoplasm; Butyrates; Butyric

1991
Drug effects on CA125 antigen expression and antibody binding to cancer cells.
    International journal of cancer, 1991, May-30, Volume: 48, Issue:3

    Topics: Antibodies, Monoclonal; Antigens, Tumor-Associated, Carbohydrate; Binding Sites, Antibody; Bucladesi

1991
Derivatives of butyric acid as potential anti-neoplastic agents.
    International journal of cancer, 1991, Aug-19, Volume: 49, Issue:1

    Topics: Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Dose-R

1991
Pretranslational regulation of ectopic hCG alpha production in ChaGo lung cancer cells by sodium butyrate.
    Biochemical and biophysical research communications, 1985, Dec-31, Volume: 133, Issue:3

    Topics: Butyrates; Butyric Acid; Cell Line; Chorionic Gonadotropin; Cloning, Molecular; Gene Expression Regu

1985
Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells.
    Molecular and cellular biology, 1988, Volume: 8, Issue:9

    Topics: Animals; Butyrates; Butyric Acid; Cell Division; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide

1988
Effect of butyric acid on lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Animals; Butyrates; Butyric Acid; Cathepsins; Cell Adhesion; Cycloheximide; Endothelium; Fatty Acids

1986