butyric acid has been researched along with Lung Neoplasms in 24 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We developed a mitomycin C (MMC)-resistant human lung adenocarcinoma cell subline, SPC-A1/DM4, from cloned SPC-A1/D13 parent cells by 1 h exposures to escalating concentrations of the drug over 17 months." | 7.68 | Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. ( Dong, QG; Gong, LL; Wang, EZ; Wang, HJ, 1993) |
| " We found that polar compounds and butyric acid, which are known to alter the expressions of normally silent genes, enhanced the lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells." | 4.77 | Modification of the metastatic potential of tumor cells by drugs. ( Takenaga, K, 1986) |
| "A low concentration of differentiation inducers such as dimethylsulphoxide (DMSO), sodium butyrate, hexamethylene bisacetamide and sodium phenylacetate greatly enhanced the antiproliferative effect in vitro and in vivo of interferon alpha (IFN-alpha) to several human lung adenocarcinoma cells." | 3.69 | Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents. ( Goto, I; Honma, Y; Yamamoto-Yamaguchi, Y, 1996) |
| "We developed a mitomycin C (MMC)-resistant human lung adenocarcinoma cell subline, SPC-A1/DM4, from cloned SPC-A1/D13 parent cells by 1 h exposures to escalating concentrations of the drug over 17 months." | 3.68 | Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance. ( Dong, QG; Gong, LL; Wang, EZ; Wang, HJ, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (20.83) | 18.7374 |
| 1990's | 9 (37.50) | 18.2507 |
| 2000's | 2 (8.33) | 29.6817 |
| 2010's | 6 (25.00) | 24.3611 |
| 2020's | 2 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Cristiano, C | 1 |
| Cuozzo, M | 1 |
| Coretti, L | 1 |
| Liguori, FM | 1 |
| Cimmino, F | 1 |
| Turco, L | 1 |
| Avagliano, C | 1 |
| Aviello, G | 1 |
| Mollica, MP | 1 |
| Lembo, F | 1 |
| Russo, R | 1 |
| Xiao, X | 2 |
| Xu, Y | 1 |
| Chen, H | 1 |
| Zhao, L | 1 |
| Bin, S | 1 |
| He, HL | 1 |
| Yang, JM | 1 |
| Pu, YC | 1 |
| Gao, CH | 1 |
| Wang, H | 1 |
| Wang, BL | 1 |
| Chen, CQ | 1 |
| Chen, CS | 1 |
| Chen, JJ | 1 |
| Zhou, LP | 1 |
| Xu, HL | 1 |
| Jin, WW | 1 |
| Wu, JB | 1 |
| Gao, SM | 1 |
| Jin, X | 1 |
| Wu, N | 1 |
| Dai, J | 1 |
| Li, Q | 1 |
| Hichino, A | 1 |
| Okamoto, M | 1 |
| Taga, S | 1 |
| Akizuki, R | 1 |
| Endo, S | 1 |
| Matsunaga, T | 1 |
| Ikari, A | 1 |
| Guo, R | 1 |
| Zhang, Y | 1 |
| Liang, S | 1 |
| Xu, H | 1 |
| Zhang, M | 1 |
| Li, B | 1 |
| Edmond, V | 1 |
| Brambilla, C | 1 |
| Brambilla, E | 1 |
| Gazzeri, S | 1 |
| Eymin, B | 1 |
| Sonnemann, J | 1 |
| Gänge, J | 1 |
| Kumar, KS | 1 |
| Müller, C | 1 |
| Bader, P | 1 |
| Beck, JF | 1 |
| Bártová, E | 1 |
| Pacherník, J | 1 |
| Harnicarová, A | 1 |
| Kovarík, A | 1 |
| Kovaríková, M | 1 |
| Hofmanová, J | 1 |
| Skalníková, M | 1 |
| Kozubek, M | 1 |
| Kozubek, S | 1 |
| Ghosh, NK | 1 |
| Tang, DC | 1 |
| Johnston, SA | 1 |
| Carbone, DP | 1 |
| Chen, Z | 1 |
| Ke, Y | 1 |
| Chen, Y | 1 |
| Dong, QG | 1 |
| Gong, LL | 1 |
| Wang, HJ | 1 |
| Wang, EZ | 1 |
| Khan, MZ | 1 |
| Freshney, RI | 1 |
| McNicol, AM | 1 |
| Murray, AM | 1 |
| Goto, I | 1 |
| Yamamoto-Yamaguchi, Y | 1 |
| Honma, Y | 1 |
| Nakai, T | 2 |
| Ishima, R | 1 |
| Sakahara, H | 2 |
| Endo, K | 2 |
| Konishi, J | 1 |
| Akasaka, K | 1 |
| Hay, FG | 1 |
| Duncan, LW | 1 |
| Langdon, SP | 1 |
| Leonard, RC | 1 |
| Hosono, M | 1 |
| Saga, T | 1 |
| Watanabe, Y | 1 |
| Imai, K | 1 |
| Yachi, A | 1 |
| Kiyozuka, Y | 1 |
| Ishiwata, I | 1 |
| Rephaeli, A | 1 |
| Rabizadeh, E | 1 |
| Aviram, A | 1 |
| Shaklai, M | 1 |
| Ruse, M | 1 |
| Nudelman, A | 1 |
| Nagelberg, SB | 1 |
| Burnside, J | 1 |
| Maniatis, A | 1 |
| Lippman, SS | 1 |
| Weintraub, BD | 1 |
| Takenaga, K | 3 |
| Nakamura, Y | 1 |
| Sakiyama, S | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Study on Fluids Associated to Lung Cancer, of the Ectopic Expression of Cancer Testis Gene and Mutation as Diagnostics and Prognosis Biomarkers[NCT02853006] | 31 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for butyric acid and Lung Neoplasms
| Article | Year |
|---|---|
Histone deacetylase inhibitors interact synergistically with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) to induce apoptosis in carcinoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Butyric Acid; Caspase 3; Caspases; | 2005 |
Modification of the metastatic potential of tumor cells by drugs.
Topics: Animals; Azacitidine; Butyrates; Butyric Acid; Carcinoma; Cell Division; Cell Line; Cells, Cultured; | 1986 |
22 other studies available for butyric acid and Lung Neoplasms
| Article | Year |
|---|---|
Oral sodium butyrate supplementation ameliorates paclitaxel-induced behavioral and intestinal dysfunction.
Topics: Animals; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Dietary Supplements; Gastrointestinal Microbi | 2022 |
Sodium butyrate-activated TRAF6-TXNIP pathway affects A549 cells proliferation and migration.
Topics: A549 Cells; Animals; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Cell Movement; | 2020 |
Sodium butyrate increases P-gp expression in lung cancer by upregulation of STAT3 and mRNA stabilization of ABCB1.
Topics: A549 Cells; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfami | 2018 |
Histone deacetylases inhibitor trichostatin A increases the expression of Dleu2/miR-15a/16-1 via HDAC3 in non-small cell lung cancer.
Topics: Acetylation; Apoptosis; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Cell Cycle Checkpoints; Cell L | 2013 |
TXNIP mediates the differential responses of A549 cells to sodium butyrate and sodium 4-phenylbutyrate treatment.
Topics: A549 Cells; Butyric Acid; Carcinoma, Non-Small-Cell Lung; Carrier Proteins; Caspase 3; Caspase 7; Ce | 2017 |
Down-regulation of Claudin-2 Expression and Proliferation by Epigenetic Inhibitors in Human Lung Adenocarcinoma A549 Cells.
Topics: A549 Cells; Adenocarcinoma; Adenocarcinoma of Lung; Azacitidine; Butyric Acid; Cell Proliferation; C | 2017 |
Sodium butyrate enhances the expression of baculovirus-mediated sodium/iodide symporter gene in A549 lung adenocarcinoma cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Baculoviridae; Biological Transport; Blotting, Western; Buty | 2010 |
SRSF2 is required for sodium butyrate-mediated p21(WAF1) induction and premature senescence in human lung carcinoma cell lines.
Topics: Butyric Acid; Cell Line, Tumor; Cellular Senescence; Cyclin-Dependent Kinase Inhibitor p21; Histone | 2011 |
Nuclear levels and patterns of histone H3 modification and HP1 proteins after inhibition of histone deacetylases.
Topics: Apoptosis; Butyric Acid; Carcinoma, Small Cell; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Nucleu | 2005 |
Drug-induced biochemical markers of cancer in cervical carcinoma cells.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Chorionic Gonadotropin; Cho | 1982 |
Butyrate-inducible and tumor-restricted gene expression by adenovirus vectors.
Topics: Adenoviruses, Human; Animals; beta-Galactosidase; Butyrates; Butyric Acid; Carcinoma; Cytomegaloviru | 1994 |
A serum-free medium for hybridoma cell culture.
Topics: Animals; Antibodies, Monoclonal; Butyrates; Butyric Acid; Carcinoma, Small Cell; Cell Division; Cult | 1993 |
Isolation of a mitomycin-resistant human lung adenocarcinoma cell subline to investigate the modulation by sodium butyrate of cell growth and drug resistance.
Topics: Adenocarcinoma; Butyrates; Butyric Acid; Cell Division; Cell Survival; Cisplatin; DNA, Neoplasm; Dru | 1993 |
Induction of phenotypic changes in SCLC cell lines in vitro by hexamethylene bisacetamide, sodium butyrate, and cyclic AMP.
Topics: Acetamides; Animals; Antineoplastic Agents; Biomarkers, Tumor; Butyrates; Butyric Acid; Carcinoma, S | 1993 |
Enhancement of sensitivity of human lung adenocarcinoma cells to growth-inhibitory activity of interferon alpha by differentiation-inducing agents.
Topics: Acetamides; Adenocarcinoma; Alkaline Phosphatase; Animals; Antineoplastic Agents; Biomarkers; Butyra | 1996 |
1H-magnetic resonance spectroscopic observation of cultured malignant cells pharmacologically induced to different phenotypes.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Hormonal; Butyrates; Butyric Acid; Cho | 1996 |
Modulation of the cluster 1 and mucin antigens in human small cell lung cancer and other epithelial tumour cell lines after treatment with the differentiation inducing agent, sodium butyrate.
Topics: Adenocarcinoma; Alkaline Phosphatase; Antibodies, Monoclonal; Antigens, Neoplasm; Butyrates; Butyric | 1991 |
Drug effects on CA125 antigen expression and antibody binding to cancer cells.
Topics: Antibodies, Monoclonal; Antigens, Tumor-Associated, Carbohydrate; Binding Sites, Antibody; Bucladesi | 1991 |
Derivatives of butyric acid as potential anti-neoplastic agents.
Topics: Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Dose-R | 1991 |
Pretranslational regulation of ectopic hCG alpha production in ChaGo lung cancer cells by sodium butyrate.
Topics: Butyrates; Butyric Acid; Cell Line; Chorionic Gonadotropin; Cloning, Molecular; Gene Expression Regu | 1985 |
Differential expression of a tropomyosin isoform in low- and high-metastatic Lewis lung carcinoma cells.
Topics: Animals; Butyrates; Butyric Acid; Cell Division; Dimethyl Sulfoxide; Electrophoresis, Polyacrylamide | 1988 |
Effect of butyric acid on lung-colonizing ability of cloned low-metastatic Lewis lung carcinoma cells.
Topics: Animals; Butyrates; Butyric Acid; Cathepsins; Cell Adhesion; Cycloheximide; Endothelium; Fatty Acids | 1986 |