butyric acid has been researched along with Leukemia in 11 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Leukemia: A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Butyric acid (BUT) was used as positive control." | 1.28 | Alterations of growth fraction and DNA content in K562 cells by differentiating agents. ( Carpentier, Y; Comoe, L; Desoize, B; Gorisse, MC; Joly, P, 1990) |
| " at a dosage of 500 mg/kg/day as continuous infusion over 10 days." | 1.27 | Clinical pharmacology of sodium butyrate in patients with acute leukemia. ( Kurschel, E; Miller, AA; Osieka, R; Schmidt, CG, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (54.55) | 18.7374 |
| 1990's | 5 (45.45) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gambari, R | 2 |
| Raschellà, G | 1 |
| Tripodi, M | 1 |
| Farace, MG | 1 |
| Fantoni, A | 1 |
| Werkmeister, JA | 1 |
| Pross, HF | 1 |
| Roder, JC | 1 |
| Marks, DC | 1 |
| Davey, MW | 1 |
| Davey, RA | 1 |
| Kidman, AD | 1 |
| Breitman, TR | 1 |
| Chen, ZX | 1 |
| Takahashi, N | 1 |
| Saito, H | 1 |
| Hayakawa, T | 1 |
| Mita, H | 1 |
| Akiyama, K | 1 |
| Shida, T | 1 |
| Rowley, PT | 1 |
| Farley, BA | 1 |
| LaBella, S | 1 |
| Giuliano, R | 1 |
| Leary, JF | 1 |
| Gorisse, MC | 1 |
| Carpentier, Y | 1 |
| Joly, P | 1 |
| Comoe, L | 1 |
| Desoize, B | 1 |
| Petraki, H | 1 |
| Ioannides, CG | 1 |
| Filli, S | 1 |
| Papamichail, M | 1 |
| Miller, AA | 1 |
| Kurschel, E | 1 |
| Osieka, R | 1 |
| Schmidt, CG | 1 |
| Garson, D | 1 |
| Dokhélar, MC | 1 |
| Wakasugi, H | 1 |
| Mishal, Z | 1 |
| Tursz, T | 1 |
1 review available for butyric acid and Leukemia
| Article | Year |
|---|---|
Potential applications of cytodifferentiation therapy in hematologic malignancies.
Topics: Antineoplastic Combined Chemotherapy Protocols; Butyrates; Butyric Acid; Cell Differentiation; Child | 1994 |
10 other studies available for butyric acid and Leukemia
| Article | Year |
|---|---|
A monoclonal antibody to human transferrin receptor which inhibits erythroid differentiation of human leukemic K-562 cells.
Topics: Animals; Antibodies, Monoclonal; Azacitidine; Butyrates; Butyric Acid; Cell Differentiation; Cell Li | 1984 |
Desferrioxamine inhibits induced erythroid differentiation of human leukemic K-562 cells.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Deferoxamine; Erythroblasts; Erythrocy | 1983 |
Modulation of K562 cells with sodium butyrate. Association of impaired NK susceptibility with sialic acid and analysis of other parameters.
Topics: Butyrates; Butyric Acid; Carbohydrates; Cell Differentiation; Cell Line; Cytotoxicity, Immunologic; | 1983 |
Expression of multidrug resistance in response to differentiation in the K562 human leukaemia cell line.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Butyrates; Butyric Acid; Cell Differentiati | 1995 |
Effect of butyric acid on induction of differentiation into eosinophil-like cells in human eosinophilic leukemia cells, EoL-1 cell line: possible role of granulocyte-macrophage colony-stimulating factor as an autocrine differentiating factor.
Topics: Antibodies; Base Sequence; Blood Proteins; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; | 1993 |
Single K562 human leukemia cells express and are inducible for both erythroid and megakaryocytic antigens.
Topics: Antigens, Differentiation; Butyrates; Butyric Acid; Erythrocytes; Flow Cytometry; Glycophorins; Hema | 1992 |
Alterations of growth fraction and DNA content in K562 cells by differentiating agents.
Topics: Aclarubicin; Alkaloids; Antibodies, Monoclonal; Antigens, Neoplasm; Antigens, Surface; Antineoplasti | 1990 |
Loss and reappearance of transferrin receptors in human leukemic cell lines.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; DNA Replication; Heme; | 1986 |
Clinical pharmacology of sodium butyrate in patients with acute leukemia.
Topics: Adult; Aged; Blood Cell Count; Blood Proteins; Butyrates; Butyric Acid; Chromatography, High Pressur | 1987 |
HLA class-I and class-II antigen expression by human leukemic K562 cells and by Burkitt-K562 hybrids: modulation by differentiation inducers and interferon.
Topics: Burkitt Lymphoma; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Gene Expression Regulati | 1985 |