butyric acid has been researched along with Innate Inflammatory Response in 72 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Excerpt | Relevance | Reference |
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"This study suggests that maternal melatonin supplementation can shape the gut microbiota and metabolism of offspring under normal physiological conditions and protect them against LPS-induced inflammation in early life." | 8.31 | Maternal melatonin supplementation shapes gut microbiota and protects against inflammation in early life. ( Cai, Y; Feng, Z; Hao, H; Ke, Q; Lai, J; Li, F; Li, S; Liu, X; Lu, Z; Ma, F; Xiao, X, 2023) |
"This is the first report where intranasal curcumin inhibited asthma severity via affecting HDAC 1 (H3acK9) leading to NF-kB suppression in mouse model of allergic asthma." | 8.12 | Intranasal curcumin and sodium butyrate modulates airway inflammation and fibrosis via HDAC inhibition in allergic asthma. ( Dash, D; Islam, R; Singh, R, 2022) |
" The present study aimed to evaluate the protective effect of SB against L-arginine (L-Arg)-induced pancreatic fibrosis in Wistar rats." | 7.81 | Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. ( Jena, G; Kanika, G; Khan, S, 2015) |
"Butyric acid treatment increased HuR expression in both cytoplasm and nucleus and decreased the level of p-AMPK and p-ACC, while transfection of AMPK activator or HuR-siRNA would down-regulate HuR expression." | 5.62 | Butyric acid alleviated chronic intermittent hypoxia-induced lipid formation and inflammation through up-regulating HuR expression and inactivating AMPK pathways. ( Abdullahi, R; He, Y; Huang, N; Ren, X; Su, M; Xu, M; Xue, S; Yu, J, 2021) |
"Humic acid (MFG) and fat-protected butyric acid (BA) has been shown to modulate energy metabolism and inflammation." | 5.19 | Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs. ( Edmonds, MS; Gabler, NK; Johal, S; Kerr, BJ; Moreland, S; van Sambeek, DM; Weber, TE, 2014) |
"This study suggests that maternal melatonin supplementation can shape the gut microbiota and metabolism of offspring under normal physiological conditions and protect them against LPS-induced inflammation in early life." | 4.31 | Maternal melatonin supplementation shapes gut microbiota and protects against inflammation in early life. ( Cai, Y; Feng, Z; Hao, H; Ke, Q; Lai, J; Li, F; Li, S; Liu, X; Lu, Z; Ma, F; Xiao, X, 2023) |
"This is the first report where intranasal curcumin inhibited asthma severity via affecting HDAC 1 (H3acK9) leading to NF-kB suppression in mouse model of allergic asthma." | 4.12 | Intranasal curcumin and sodium butyrate modulates airway inflammation and fibrosis via HDAC inhibition in allergic asthma. ( Dash, D; Islam, R; Singh, R, 2022) |
" Treatment should be aimed at possible causes of intestinal damage (Clostridioides difficile), as well as reducing inflammation, restoring intestinal permeability, cytoprotection of mucosal cells, replenishing butyric acid deficiency." | 4.12 | [Features of the intestine conditions at patients with a new coronavirus infection]. ( Ardatskaya, MD; Butorova, LI; Topchiy, TВ; Мinushkin, ОN; Маslovskii, LV, 2022) |
" Liver damage, markers of glucose metabolism, inflammation, intestinal barrier function and melatonin metabolism were determined." | 3.96 | Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis. ( Baumann, A; Bergheim, I; Brandt, A; Burkard, M; Jin, CJ; Nier, A; Sellmann, C; Venturelli, S, 2020) |
" The present study is aimed at testing the hypothesis that resistant maltodextrin (RM), a soluble dietary fiber produced by starch debranching, alleviated dextran sulfate sodium- (DSS-) induced colitis in mice." | 3.96 | Resistant Maltodextrin Alleviates Dextran Sulfate Sodium-Induced Intestinal Inflammatory Injury by Increasing Butyric Acid to Inhibit Proinflammatory Cytokine Levels. ( Han, D; Huang, S; Pang, J; Wang, J; Wang, S; Wu, Y; Wu, Z; Zhang, S, 2020) |
" The present study aimed to evaluate the protective effect of SB against L-arginine (L-Arg)-induced pancreatic fibrosis in Wistar rats." | 3.81 | Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. ( Jena, G; Kanika, G; Khan, S, 2015) |
"Chronic low-grade inflammation is regarded to an important signature of atherosclerosis (AS)." | 1.91 | Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE-/- mice. ( Bai, Z; Guo, M; Jia, S; Jiang, X; Li, A; Li, Y; Liu, Y; Ma, H; Ma, P; Ren, Y; Wang, H; Wang, R; Wang, T; Yan, R; Yang, L; Zhang, P; Zhang, Q; Zhang, X, 2023) |
"We induced ulcerative colitis (UC) in mice utilizing dextran sodium sulfate (DSS) in the drinking water for 7 days." | 1.91 | Sodium Butyrate Protects Against Intestinal Oxidative Damage and Neuroinflammation in the Prefrontal Cortex of Ulcerative Colitis Mice Model. ( De Oliveira, J; do Nascimento, ND; Fröhlich, NT; Gelain, DP; Gomes, HM; Kessler, F; Martins, A; Moreira, JCF; Paz, AH; Possa, L; Rodrigues, MS; Santos, L; Silveira, AK; Sirena, D, 2023) |
"The onset and progression of COPD are affected by multiple environmental and genetic risk factors, such as inflammatory mechanisms, oxidative stress, and an imbalance between proteinase and antiprotease." | 1.91 | Sodium butyrate (SB) ameliorated inflammation of COPD induced by cigarette smoke through activating the GPR43 to inhibit NF-κB/MAPKs signaling pathways. ( Jia, W; Kang, Y; Li, Q; Qiu, Z; Tong, Y; Wang, P; Wu, G; Xu, C; Zhao, Z, 2023) |
"Burns are a common traumatic injuries with considerable morbidity and mortality rates." | 1.72 | Combination of sodium butyrate and probiotics ameliorates severe burn-induced intestinal injury by inhibiting oxidative stress and inflammatory response. ( Gao, Y; He, Q; Shen, G; Wang, H; Wang, L; Yan, Z; Zhou, B, 2022) |
"However, the role of butyrate in overnutrition-induced microglial activation and hypothalamic inflammation remains unclear." | 1.72 | Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation. ( Chen, T; Duan, C; Ge, X; Guo, K; Li, Y; Liu, H; Lu, H; Shang, Y; Wang, X; Zhang, D, 2022) |
" C4 dose-response experiments in the presence or absence of cytokines were performed in a co-culture system including Caco-2 cells, HepG2 cells, or both." | 1.62 | Butyric Acid Added Apically to Intestinal Caco-2 Cells Elevates Hepatic ApoA-I Transcription and Rescues Lower ApoA-I Expression in Inflamed HepG2 Cells Co-Cultured in the Basolateral Compartment. ( Mensink, RP; Plat, J; Popeijus, HE; Tayyeb, JZ, 2021) |
"Current strategies for the treatment of Alzheimer's disease (AD) focus on the pathology in the later stages of disease progression." | 1.62 | Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice. ( Jiang, Y; Li, K; Li, X; Xu, L; Yang, Z, 2021) |
"Butyric acid treatment increased HuR expression in both cytoplasm and nucleus and decreased the level of p-AMPK and p-ACC, while transfection of AMPK activator or HuR-siRNA would down-regulate HuR expression." | 1.62 | Butyric acid alleviated chronic intermittent hypoxia-induced lipid formation and inflammation through up-regulating HuR expression and inactivating AMPK pathways. ( Abdullahi, R; He, Y; Huang, N; Ren, X; Su, M; Xu, M; Xue, S; Yu, J, 2021) |
"Depression is a common disease that afflicts one in 6 people." | 1.56 | Lipopolysaccharide-Induced Depression-Like Behaviors Is Ameliorated by Sodium Butyrate via Inhibiting Neuroinflammation and Oxido-Nitrosative Stress. ( Chen, J; Chen, Z; He, H; Huang, C; Li, Y; Liu, R; Ma, Y; Qiu, J; Tong, L; You, Q, 2020) |
"Butyrate might thus be valuable in the treatment of sepsis, in which inhibition of overwhelming cytokine release is vitally important." | 1.51 | Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis. ( Fu, J; Li, G; Wu, X; Zang, B, 2019) |
"Butyric acid is a beneficial feed additive used in animal production, including poultry production." | 1.51 | Effects of sodium butyrate on intestinal health and gut microbiota composition during intestinal inflammation progression in broilers. ( Ji, J; Li, Y; Liu, TF; Luo, CL; Qu, H; Shu, DM; Wang, J; Wang, Y; Zou, X, 2019) |
"Despite extensive research, anastomotic leakage (AL) remains one of the most dreaded complications after colorectal surgery." | 1.46 | Comparison of three different application routes of butyrate to improve colonic anastomotic strength in rats. ( Boonen, BT; Bosmans, JW; Bouvy, ND; Gijbels, MJ; Jongen, AC; Marsich, E; Scognamiglio, F; Stucchi, L; van Rijn, S, 2017) |
"Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease." | 1.39 | Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet. ( Calignano, A; Canani, RB; Ferrante, MC; Iacono, A; Mattace Raso, G; Meli, R; Paciello, O; Russo, R; Santoro, A; Simeoli, R, 2013) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 1 (1.39) | 18.2507 |
2000's | 1 (1.39) | 29.6817 |
2010's | 26 (36.11) | 24.3611 |
2020's | 44 (61.11) | 2.80 |
Authors | Studies |
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Deng, M | 2 |
Wu, X | 2 |
Duan, X | 1 |
Xu, J | 1 |
Yang, X | 1 |
Sheng, X | 1 |
Lou, P | 1 |
Shao, C | 1 |
Lv, C | 1 |
Yu, Z | 1 |
Islam, R | 1 |
Dash, D | 1 |
Singh, R | 1 |
Bayazid, AB | 2 |
Kim, JG | 2 |
Azam, S | 1 |
Jeong, SA | 1 |
Kim, DH | 1 |
Park, CW | 1 |
Lim, BO | 2 |
Zhou, B | 1 |
Wang, L | 1 |
Gao, Y | 1 |
He, Q | 1 |
Yan, Z | 1 |
Wang, H | 4 |
Shen, G | 1 |
Dou, X | 1 |
Yan, D | 1 |
Ma, Z | 1 |
Gao, N | 1 |
Shan, A | 1 |
Ortiz, AM | 1 |
Simpson, J | 1 |
Langner, CA | 1 |
Baker, PJ | 1 |
Aguilar, C | 1 |
Brooks, K | 1 |
Flynn, JK | 1 |
Vinton, CL | 1 |
Rahmberg, AR | 1 |
Hickman, HD | 1 |
Brenchley, JM | 1 |
Ali, I | 1 |
Li, C | 2 |
Kuang, M | 1 |
Shah, AU | 1 |
Shafiq, M | 1 |
Ahmad, MA | 1 |
Abdalmegeed, D | 1 |
Li, L | 1 |
Wang, G | 1 |
Kaya-Sezginer, E | 1 |
Yilmaz-Oral, D | 1 |
Kırlangıç, OF | 1 |
Yilmaz, S | 1 |
Özen, FZ | 1 |
Aşan, M | 1 |
Gur, S | 1 |
Zhou, T | 1 |
Xu, H | 2 |
Cheng, X | 1 |
He, Y | 2 |
Ren, Q | 1 |
Li, D | 1 |
Xie, Y | 2 |
Gao, C | 1 |
Zhang, Y | 4 |
Sun, X | 2 |
Xu, Y | 1 |
Huang, W | 1 |
Wang, X | 2 |
Duan, C | 1 |
Li, Y | 5 |
Lu, H | 1 |
Guo, K | 1 |
Ge, X | 1 |
Chen, T | 1 |
Shang, Y | 1 |
Liu, H | 1 |
Zhang, D | 1 |
Topchiy, TВ | 1 |
Ardatskaya, MD | 1 |
Butorova, LI | 1 |
Маslovskii, LV | 1 |
Мinushkin, ОN | 1 |
Gao, L | 1 |
Davies, DL | 1 |
Asatryan, L | 1 |
Yan, M | 1 |
Li, X | 2 |
Sun, C | 1 |
Tan, J | 1 |
Liu, Y | 4 |
Li, M | 1 |
Qi, Z | 1 |
He, J | 1 |
Wang, D | 1 |
Wu, L | 1 |
Choi, Y | 1 |
Choi, SI | 1 |
Kim, N | 1 |
Nam, RH | 1 |
Jang, JY | 1 |
Na, HY | 1 |
Shin, CM | 1 |
Lee, DH | 1 |
Min, H | 1 |
Kim, YR | 1 |
Seok, YJ | 1 |
Guo, TT | 1 |
Zhang, Z | 1 |
Sun, Y | 1 |
Zhu, RY | 1 |
Wang, FX | 1 |
Ma, LJ | 1 |
Jiang, L | 1 |
Liu, HD | 1 |
Ma, H | 1 |
Yang, L | 1 |
Yan, R | 1 |
Wang, R | 1 |
Zhang, P | 1 |
Bai, Z | 1 |
Ren, Y | 1 |
Jiang, X | 1 |
Wang, T | 2 |
Ma, P | 1 |
Zhang, Q | 1 |
Li, A | 1 |
Guo, M | 1 |
Zhang, X | 2 |
Jia, S | 1 |
Haskey, N | 1 |
Estaki, M | 1 |
Ye, J | 1 |
Shim, RK | 1 |
Singh, S | 1 |
Dieleman, LA | 1 |
Jacobson, K | 1 |
Gibson, DL | 1 |
Liu, K | 1 |
He, X | 1 |
Huang, J | 2 |
Yu, S | 1 |
Cui, M | 1 |
Gao, M | 2 |
Liu, L | 1 |
Qian, Y | 1 |
Hui, M | 1 |
Hong, Y | 1 |
Nie, X | 1 |
Li, F | 1 |
Lai, J | 1 |
Ma, F | 1 |
Cai, Y | 1 |
Li, S | 1 |
Feng, Z | 1 |
Lu, Z | 1 |
Liu, X | 1 |
Ke, Q | 1 |
Hao, H | 1 |
Xiao, X | 1 |
Ikeda, Y | 1 |
Matsuda, S | 1 |
Zong, Q | 1 |
Li, K | 2 |
Qu, H | 2 |
Hu, P | 1 |
Xu, C | 3 |
Wu, S | 1 |
Wang, S | 2 |
Liu, HY | 1 |
Cai, D | 1 |
Bao, W | 1 |
Silveira, AK | 1 |
Gomes, HM | 1 |
Fröhlich, NT | 1 |
Possa, L | 1 |
Santos, L | 1 |
Kessler, F | 1 |
Martins, A | 1 |
Rodrigues, MS | 1 |
De Oliveira, J | 1 |
do Nascimento, ND | 1 |
Sirena, D | 1 |
Paz, AH | 1 |
Gelain, DP | 1 |
Moreira, JCF | 1 |
Zhao, Z | 1 |
Tong, Y | 1 |
Kang, Y | 1 |
Qiu, Z | 1 |
Li, Q | 1 |
Wu, G | 1 |
Jia, W | 1 |
Wang, P | 2 |
Keshari, S | 1 |
Balasubramaniam, A | 1 |
Myagmardoloonjin, B | 1 |
Herr, DR | 1 |
Negari, IP | 1 |
Huang, CM | 1 |
Lewis, G | 1 |
Wang, B | 1 |
Shafiei Jahani, P | 1 |
Hurrell, BP | 1 |
Banie, H | 1 |
Aleman Muench, GR | 1 |
Maazi, H | 1 |
Helou, DG | 1 |
Howard, E | 1 |
Galle-Treger, L | 1 |
Lo, R | 1 |
Santosh, S | 1 |
Baltus, A | 1 |
Bongers, G | 1 |
San-Mateo, L | 1 |
Gilliland, FD | 1 |
Rehan, VK | 1 |
Soroosh, P | 1 |
Akbari, O | 1 |
Busbee, PB | 1 |
Menzel, L | 1 |
Alrafas, HR | 1 |
Dopkins, N | 1 |
Becker, W | 1 |
Miranda, K | 1 |
Tang, C | 1 |
Chatterjee, S | 1 |
Singh, U | 1 |
Nagarkatti, M | 1 |
Nagarkatti, PS | 1 |
Anderson, G | 1 |
Maes, M | 1 |
de Lazari, MGT | 1 |
Pereira, LX | 1 |
Orellano, LAA | 1 |
Scheuermann, K | 1 |
Machado, CT | 1 |
Vasconcelos, AC | 1 |
Andrade, SP | 1 |
Campos, PP | 1 |
Qiu, J | 1 |
Liu, R | 1 |
Ma, Y | 1 |
Chen, Z | 3 |
He, H | 1 |
Chen, J | 1 |
Tong, L | 1 |
Huang, C | 2 |
You, Q | 1 |
Baumann, A | 1 |
Jin, CJ | 1 |
Brandt, A | 1 |
Sellmann, C | 1 |
Nier, A | 1 |
Burkard, M | 1 |
Venturelli, S | 1 |
Bergheim, I | 1 |
Qu, F | 1 |
Chen, L | 1 |
Liu, C | 2 |
Zhang, M | 1 |
Ren, F | 1 |
Guo, H | 1 |
Zhang, H | 1 |
Ge, S | 1 |
Wu, C | 1 |
Zhao, L | 1 |
Roshanravan, N | 1 |
Alamdari, NM | 1 |
Jafarabadi, MA | 1 |
Mohammadi, A | 1 |
Shabestari, BR | 1 |
Nasirzadeh, N | 1 |
Asghari, S | 1 |
Mansoori, B | 1 |
Akbarzadeh, M | 1 |
Ghavami, A | 1 |
Ghaffari, S | 1 |
Ostadrahimi, A | 1 |
Qiao, CM | 1 |
Sun, MF | 1 |
Jia, XB | 1 |
Zhang, BP | 1 |
Zhao, LP | 1 |
Shi, Y | 1 |
Zhou, ZL | 1 |
Zhu, YL | 1 |
Cui, C | 1 |
Shen, YQ | 1 |
Luo, S | 1 |
Jiang, C | 1 |
Tang, Y | 1 |
Cao, Z | 1 |
Jia, H | 1 |
Xu, Q | 1 |
Zhao, C | 1 |
Loor, JJ | 1 |
Zhang, S | 1 |
Huang, S | 1 |
Wu, Z | 1 |
Pang, J | 1 |
Wu, Y | 2 |
Wang, J | 3 |
Han, D | 1 |
Luzardo-Ocampo, I | 1 |
Loarca-Piña, G | 1 |
Gonzalez de Mejia, E | 1 |
Yang, T | 1 |
Yang, H | 1 |
Heng, C | 1 |
Chen, S | 1 |
Hu, Y | 1 |
Jiang, Z | 1 |
Yu, Q | 1 |
Wang, Z | 1 |
Qian, S | 1 |
Du, L | 1 |
Lu, Q | 1 |
Yin, X | 1 |
Pla, R | 1 |
Pujos-Guillot, E | 1 |
Durand, S | 1 |
Brandolini-Bunlon, M | 1 |
Centeno, D | 1 |
Pyne, DB | 1 |
Toussaint, JF | 1 |
Hellard, P | 1 |
Tayyeb, JZ | 1 |
Popeijus, HE | 1 |
Mensink, RP | 1 |
Plat, J | 1 |
Huang, Y | 1 |
Ding, Y | 1 |
Shen, C | 1 |
Chen, X | 2 |
Jiang, Y | 1 |
Xu, L | 1 |
Yang, Z | 1 |
Su, M | 1 |
Xue, S | 1 |
Yu, J | 1 |
Ren, X | 1 |
Huang, N | 1 |
Abdullahi, R | 1 |
Xu, M | 1 |
Zhou, Q | 1 |
Gu, R | 1 |
Xue, B | 1 |
Li, P | 1 |
Gu, Q | 1 |
Jang, YA | 1 |
Kim, YM | 1 |
Liu, FY | 1 |
Wen, J | 1 |
Hou, J | 1 |
Zhang, SQ | 1 |
Sun, CB | 1 |
Zhou, LC | 1 |
Yin, W | 1 |
Pang, WL | 1 |
Wang, C | 1 |
Ying, Y | 1 |
Han, SS | 1 |
Yan, JY | 1 |
Li, CX | 1 |
Yuan, JL | 1 |
Xing, HJ | 1 |
Yang, ZS | 1 |
Liu, J | 2 |
Chang, G | 2 |
Ma, N | 2 |
Wang, Y | 4 |
Roy, AC | 2 |
Shen, X | 2 |
Zhou, D | 2 |
Pan, Q | 2 |
Shen, F | 1 |
Cao, HX | 1 |
Ding, WJ | 1 |
Chen, YW | 2 |
Fan, JG | 2 |
Wang, JJ | 1 |
Wei, ZK | 1 |
Wang, YN | 1 |
Fu, YH | 1 |
Yang, ZT | 1 |
Gong, Y | 1 |
Yang, R | 1 |
Hu, W | 1 |
Xu, X | 1 |
Qin, Y | 1 |
Lanza, M | 1 |
Campolo, M | 1 |
Casili, G | 1 |
Filippone, A | 1 |
Paterniti, I | 1 |
Cuzzocrea, S | 1 |
Esposito, E | 1 |
Dai, J | 1 |
Yang, P | 1 |
Xu, W | 1 |
Ai, Q | 1 |
Zhang, W | 1 |
Mai, K | 1 |
Fu, J | 1 |
Li, G | 1 |
Zang, B | 1 |
Roy, S | 1 |
Aabdin, ZU | 1 |
Fang, W | 1 |
Xue, H | 1 |
Chen, K | 1 |
Ling, W | 1 |
Zou, X | 1 |
Ji, J | 1 |
Shu, DM | 1 |
Liu, TF | 1 |
Luo, CL | 1 |
Abdelli, LS | 1 |
Samsam, A | 1 |
Naser, SA | 1 |
Mattace Raso, G | 1 |
Simeoli, R | 1 |
Russo, R | 1 |
Iacono, A | 1 |
Santoro, A | 1 |
Paciello, O | 1 |
Ferrante, MC | 1 |
Canani, RB | 1 |
Calignano, A | 1 |
Meli, R | 1 |
Liang, X | 1 |
Wang, RS | 1 |
Wang, F | 1 |
Liu, S | 1 |
Guo, F | 1 |
Sun, L | 1 |
Wang, YJ | 1 |
Sun, YX | 1 |
Chen, XL | 1 |
Farkas, O | 1 |
Mátis, G | 1 |
Pászti-Gere, E | 1 |
Palócz, O | 1 |
Kulcsár, A | 1 |
Petrilla, J | 1 |
Csikó, G | 1 |
Neogrády, Z | 1 |
Gálfi, P | 1 |
Weber, TE | 1 |
van Sambeek, DM | 1 |
Gabler, NK | 1 |
Kerr, BJ | 1 |
Moreland, S | 1 |
Johal, S | 1 |
Edmonds, MS | 1 |
Kanika, G | 1 |
Khan, S | 1 |
Jena, G | 1 |
He, G | 1 |
Peng, Y | 1 |
Zhong, W | 1 |
Zhang, B | 1 |
Subramanian, U | 1 |
Kumar, P | 1 |
Mani, I | 1 |
Chen, D | 1 |
Kessler, I | 1 |
Periyasamy, R | 1 |
Raghavaraju, G | 1 |
Pandey, KN | 1 |
Reijnders, D | 1 |
Goossens, GH | 1 |
Hermes, GD | 1 |
Neis, EP | 1 |
van der Beek, CM | 1 |
Most, J | 1 |
Holst, JJ | 1 |
Lenaerts, K | 1 |
Kootte, RS | 1 |
Nieuwdorp, M | 1 |
Groen, AK | 1 |
Olde Damink, SW | 1 |
Boekschoten, MV | 1 |
Smidt, H | 1 |
Zoetendal, EG | 1 |
Dejong, CH | 1 |
Blaak, EE | 1 |
Astakhova, L | 1 |
Ngara, M | 1 |
Babich, O | 1 |
Prosekov, A | 1 |
Asyakina, L | 1 |
Dyshlyuk, L | 1 |
Midtvedt, T | 1 |
Zhou, X | 1 |
Ernberg, I | 1 |
Matskova, L | 1 |
Melo, AD | 1 |
Silveira, H | 1 |
Bortoluzzi, C | 1 |
Lara, LJ | 1 |
Garbossa, CA | 1 |
Preis, G | 1 |
Costa, LB | 1 |
Rostagno, MH | 1 |
Shirasugi, M | 1 |
Nishioka, K | 1 |
Yamamoto, T | 1 |
Nakaya, T | 1 |
Kanamura, N | 1 |
Bosmans, JW | 1 |
Jongen, AC | 1 |
Boonen, BT | 1 |
van Rijn, S | 1 |
Scognamiglio, F | 1 |
Stucchi, L | 1 |
Gijbels, MJ | 1 |
Marsich, E | 1 |
Bouvy, ND | 1 |
Xin, FZ | 1 |
Zhang, RN | 1 |
He, CX | 1 |
Chen, GY | 1 |
Hertzel, AV | 1 |
Hellberg, K | 1 |
Reynolds, JM | 1 |
Kruse, AC | 1 |
Juhlmann, BE | 1 |
Smith, AJ | 1 |
Sanders, MA | 1 |
Ohlendorf, DH | 1 |
Suttles, J | 1 |
Bernlohr, DA | 1 |
Zeng, T | 1 |
Zhang, L | 1 |
Wischmeyer, P | 1 |
Pemberton, JH | 1 |
Phillips, SF | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
The Role of Microbiome Reprogramming on Liver Fat Accumulation[NCT03914495] | 57 participants (Actual) | Interventional | 2019-05-21 | Terminated (stopped due to PI carefully considered multiple factors and decided to close study to any further enrollment.) | |||
Effects of 3-month Probiotic Mix Supplementation (L. Helveticus R-0052, B. Longum R-0175) on Gut Microbiota and Metabolome, Endocannabinoid and Immune Systems Activation, Along With Symptoms of Fatigue in Professional Dancers[NCT05567653] | 60 participants (Anticipated) | Interventional | 2022-09-21 | Recruiting | |||
A Pilot Study of the Safety and Efficacy of AST-120 in the Treatment of Antibiotic-Refractory Pouchitis[NCT00583531] | Phase 2 | 2 participants (Actual) | Interventional | 2007-03-31 | Terminated (stopped due to Lack of enrollment) | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
1 review available for butyric acid and Innate Inflammatory Response
Article | Year |
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Gut Dysbiosis Dysregulates Central and Systemic Homeostasis via Suboptimal Mitochondrial Function: Assessment, Treatment and Classification Implications.
Topics: Butyric Acid; Cell Line; Dysbiosis; Gastrointestinal Microbiome; Homeostasis; Humans; Immune System; | 2020 |
5 trials available for butyric acid and Innate Inflammatory Response
Article | Year |
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A Mediterranean Diet Pattern Improves Intestinal Inflammation Concomitant with Reshaping of the Bacteriome in Ulcerative Colitis: A Randomised Controlled Trial.
Topics: Adult; Butyric Acid; Canada; Colitis, Ulcerative; Diet, Mediterranean; Feces; Female; Humans; Inflam | 2023 |
Effects of oral butyrate and inulin supplementation on inflammation-induced pyroptosis pathway in type 2 diabetes: A randomized, double-blind, placebo-controlled trial.
Topics: Administration, Oral; Adult; Antioxidants; Butyric Acid; Diabetes Mellitus, Type 2; Dietary Suppleme | 2020 |
Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs.
Topics: Animals; Butyric Acid; Cytokines; Dietary Fats; Escherichia coli; Humic Substances; Inflammation; In | 2014 |
Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial.
Topics: Adipocytes; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Biomarkers; Butyric Acid; Cell Shape; D | 2016 |
Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study.
Topics: Adolescent; Adult; Butyrates; Butyric Acid; Chronic Disease; Fatty Acids, Volatile; Feces; Female; G | 1993 |
66 other studies available for butyric acid and Innate Inflammatory Response
Article | Year |
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Topics: Animals; Anti-Inflammatory Agents; Butyrates; Butyric Acid; Colitis; Dextran Sulfate; Female; Gene E | 2021 |
Intranasal curcumin and sodium butyrate modulates airway inflammation and fibrosis via HDAC inhibition in allergic asthma.
Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; | 2022 |
Sodium butyrate ameliorates neurotoxicity and exerts anti-inflammatory effects in high fat diet-fed mice.
Topics: Animals; Anti-Inflammatory Agents; Body Weight; Brain; Butyric Acid; Diet, High-Fat; Inflammation; M | 2022 |
Combination of sodium butyrate and probiotics ameliorates severe burn-induced intestinal injury by inhibiting oxidative stress and inflammatory response.
Topics: Animals; Burns; Butyric Acid; Inflammation; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Pr | 2022 |
Sodium butyrate alleviates LPS-induced kidney injury via inhibiting TLR2/4 to regulate rBD2 expression.
Topics: Animals; beta-Defensins; Butyric Acid; Inflammation; Kidney; Lipopolysaccharides; Rats; RNA, Messeng | 2022 |
Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques.
Topics: Animals; Anti-Retroviral Agents; Butyric Acid; HIV Infections; Humans; Immune Reconstitution; Inflam | 2022 |
Nrf2 Activation and NF-Kb & caspase/bax signaling inhibition by sodium butyrate alleviates LPS-induced cell injury in bovine mammary epithelial cells.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Butyric Acid; Caspases; Cattle; Epithelial Cells; Fe | 2022 |
Sodium butyrate ameliorates erectile dysfunction through fibrosis in a rat model of partial bladder outlet obstruction.
Topics: Animals; Butyric Acid; Disease Models, Animal; Erectile Dysfunction; Fibrosis; Histone Deacetylases; | 2022 |
Sodium Butyrate Attenuates Diabetic Kidney Disease Partially via Histone Butyrylation Modification.
Topics: Butyric Acid; Diabetes Mellitus; Diabetic Nephropathies; Histones; Humans; Inflammation; Protein Pro | 2022 |
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
Topics: Animals; Butyric Acid; Diet, High-Fat; Hypothalamus; Inflammation; Mice; Mice, Inbred C57BL; Microgl | 2022 |
[Features of the intestine conditions at patients with a new coronavirus infection].
Topics: Butyric Acid; COVID-19; Diarrhea; Humans; Inflammation; Intestines; SARS-CoV-2 | 2022 |
Sodium Butyrate Supplementation Modulates Neuroinflammatory Response Aggravated by Antibiotic Treatment in a Mouse Model of Binge-like Ethanol Drinking.
Topics: Alcohol Drinking; Alcoholism; Animals; Anti-Bacterial Agents; Butyric Acid; Cytokines; Dietary Suppl | 2022 |
Sodium Butyrate Attenuates AGEs-Induced Oxidative Stress and Inflammation by Inhibiting Autophagy and Affecting Cellular Metabolism in THP-1 Cells.
Topics: Butyric Acid; Glycation End Products, Advanced; Humans; Inflammasomes; Inflammation; NF-kappa B; NLR | 2022 |
Effect of Clostridium butyricum on High-Fat Diet-Induced Intestinal Inflammation and Production of Short-Chain Fatty Acids.
Topics: Animals; Butyric Acid; Clostridium butyricum; Diet, High-Fat; Fatty Acids, Volatile; Female; Inflamm | 2023 |
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Topics: Animals; Butyric Acid; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; | 2023 |
Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE-/- mice.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Butyric Acid; Inflammation; Macrophages; Mice; Mice, In | 2023 |
Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome.
Topics: Animals; Butyric Acid; DNA Methylation; Fatty Acids, Volatile; Female; Fos-Related Antigen-2; Granul | 2023 |
Maternal melatonin supplementation shapes gut microbiota and protects against inflammation in early life.
Topics: Animals; Butyric Acid; Dietary Supplements; Fatty Acids, Volatile; Female; Gastrointestinal Microbio | 2023 |
Gut Protective Effect from D-Methionine or Butyric Acid against DSS and Carrageenan-Induced Ulcerative Colitis.
Topics: Animals; Butyric Acid; Carrageenan; Colitis; Colitis, Ulcerative; Dextran Sulfate; Disease Models, A | 2023 |
Sodium Butyrate Ameliorates Deoxynivalenol-Induced Oxidative Stress and Inflammation in the Porcine Liver via NR4A2-Mediated Histone Acetylation.
Topics: Acetylation; Animals; Butyric Acid; Chemical and Drug Induced Liver Injury, Chronic; Histones; Infla | 2023 |
Sodium Butyrate Protects Against Intestinal Oxidative Damage and Neuroinflammation in the Prefrontal Cortex of Ulcerative Colitis Mice Model.
Topics: Animals; Butyric Acid; Claudin-5; Colitis, Ulcerative; Disease Models, Animal; Inflammation; Inflamm | 2023 |
Sodium butyrate (SB) ameliorated inflammation of COPD induced by cigarette smoke through activating the GPR43 to inhibit NF-κB/MAPKs signaling pathways.
Topics: Animals; Anti-Inflammatory Agents; Butyric Acid; Cigarette Smoking; Inflammation; Interleukin-6; MAP | 2023 |
Butyric Acid from Probiotic
Topics: Acetolactate Synthase; Animals; Butyric Acid; Down-Regulation; Fatty Acids, Volatile; Female; Fermen | 2019 |
Dietary Fiber-Induced Microbial Short Chain Fatty Acids Suppress ILC2-Dependent Airway Inflammation.
Topics: Animals; Asthma; Butyric Acid; Dietary Fiber; Gastrointestinal Microbiome; Immunity, Innate; Inflamm | 2019 |
Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner.
Topics: Animals; Butyric Acid; Colitis; Colon; Disease Models, Animal; Dysbiosis; Female; Gastrointestinal M | 2020 |
Sodium Butyrate Downregulates Implant-Induced Inflammation in Mice.
Topics: Animals; Butyric Acid; Down-Regulation; Ethers; Histamine Antagonists; Inflammation; Inflammation Me | 2020 |
Lipopolysaccharide-Induced Depression-Like Behaviors Is Ameliorated by Sodium Butyrate via Inhibiting Neuroinflammation and Oxido-Nitrosative Stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Butyric Acid; Cytokines; Depression; Disease Model | 2020 |
Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis.
Topics: Animals; Butyric Acid; Cholesterol, Dietary; Diet, High-Fat; Dietary Supplements; Disease Models, An | 2020 |
SCFAs alleviated steatosis and inflammation in mice with NASH induced by MCD.
Topics: Acetates; Alanine Transaminase; Animals; Aspartate Aminotransferases; Butyrates; Butyric Acid; Fatty | 2020 |
Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Butyric Acid; Cell Line; Colon; C | 2020 |
Sodium butyrate reduces bovine mammary epithelial cell inflammatory responses induced by exogenous lipopolysaccharide, by inactivating NF-κB signaling.
Topics: Animals; Butyric Acid; Cattle; Epithelial Cells; Female; Inflammation; Lipopolysaccharides; Mammary | 2020 |
Resistant Maltodextrin Alleviates Dextran Sulfate Sodium-Induced Intestinal Inflammatory Injury by Increasing Butyric Acid to Inhibit Proinflammatory Cytokine Levels.
Topics: Animals; Butyric Acid; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Feces; Fe | 2020 |
Gallic and butyric acids modulated NLRP3 inflammasome markers in a co-culture model of intestinal inflammation.
Topics: Biomarkers; Butyric Acid; Caco-2 Cells; Cell Differentiation; Cell Survival; Coculture Techniques; C | 2020 |
Amelioration of non-alcoholic fatty liver disease by sodium butyrate is linked to the modulation of intestinal tight junctions in db/db mice.
Topics: Animals; Blood Glucose; Butyric Acid; Caco-2 Cells; Cholesterol; Clostridium butyricum; Colon; Cytok | 2020 |
Non-targeted metabolomics analyses by mass spectrometry to explore metabolic stress after six training weeks in high level swimmers.
Topics: Adolescent; Athletes; Butyric Acid; Carnitine; Cresols; Cross-Over Studies; Fatigue; Female; Glycoge | 2021 |
Butyric Acid Added Apically to Intestinal Caco-2 Cells Elevates Hepatic ApoA-I Transcription and Rescues Lower ApoA-I Expression in Inflamed HepG2 Cells Co-Cultured in the Basolateral Compartment.
Topics: Apolipoprotein A-I; Butyric Acid; Caco-2 Cells; Coculture Techniques; Hep G2 Cells; Humans; Inflamma | 2021 |
Effects of sodium butyrate supplementation on inflammation, gut microbiota, and short-chain fatty acids in Helicobacter pylori-infected mice.
Topics: Animals; Butyric Acid; Dietary Supplements; Fatty Acids, Volatile; Gastrointestinal Microbiome; Heli | 2021 |
Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Butyric Acid; Cognitive Dysfunction; Disea | 2021 |
Butyric acid alleviated chronic intermittent hypoxia-induced lipid formation and inflammation through up-regulating HuR expression and inactivating AMPK pathways.
Topics: Adipocytes; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory | 2021 |
Phenyl lactic acid alleviates
Topics: Animals; Anti-Inflammatory Agents; Butyric Acid; Colitis; Colon; Cytokines; Dysbiosis; Female; Gastr | 2021 |
Neuroprotective Effects of Sodium Butyrate through Suppressing Neuroinflammation and Modulating Antioxidant Enzymes.
Topics: Apoptosis Regulatory Proteins; Butyric Acid; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Glut | 2021 |
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Topics: Acetic Acid; Animals; Aorta; Atherosclerosis; Benzyl Alcohols; Butyric Acid; Disease Models, Animal; | 2021 |
Sodium butyrate pretreatment mitigates lipopolysaccharide-induced inflammation through the TLR4/NF-κB signaling pathway in bovine embryo trachea cells.
Topics: Animals; Butyric Acid; Cattle; Cattle Diseases; Inflammation; Interleukin-6; Lipopolysaccharides; NF | 2022 |
Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota.
Topics: Adipose Tissue; Animals; Body Weight; Butyric Acid; Cecum; Diet, High-Fat; Endotoxemia; Epididymis; | 2017 |
Butyrate protects against disruption of the blood-milk barrier and moderates inflammatory responses in a model of mastitis induced by lipopolysaccharide.
Topics: Animals; Butyric Acid; Disease Models, Animal; Epithelial Cells; Female; Inflammation; Lipopolysacch | 2017 |
Sodium butyrate triggers a functional elongation of microglial process via Akt-small RhoGTPase activation and HDACs inhibition.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butyric Acid; Cell Enlargement; Cells, Cultured; G | 2018 |
Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury.
Topics: Animals; Antioxidants; Butyric Acid; Cyclooxygenase 2; Inflammation; Interleukin-1beta; Male; Mice; | 2019 |
Sodium butyrate supplementation in high-soybean meal diets for turbot (Scophthalmus maximus L.): Effects on inflammatory status, mucosal barriers and microbiota in the intestine.
Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aquaculture; Bacteria; Butyric Aci | 2019 |
Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis.
Topics: Animals; Butyric Acid; Cecum; Inflammation; Intestinal Mucosa; Intestines; Ligation; NF-kappa B; Pun | 2019 |
Sodium butyrate suppresses NOD1-mediated inflammatory molecules expressed in bovine hepatocytes during iE-DAP and LPS treatment.
Topics: Animals; Butyric Acid; Cattle; Diaminopimelic Acid; Hepatocytes; Inflammation; Ligands; Lipopolysacc | 2019 |
Supplementation with Sodium Butyrate Modulates the Composition of the Gut Microbiota and Ameliorates High-Fat Diet-Induced Obesity in Mice.
Topics: Animals; Butyric Acid; Colon; Diet, High-Fat; Dietary Fats; Dietary Supplements; Dysbiosis; Gastroin | 2019 |
Effects of sodium butyrate on intestinal health and gut microbiota composition during intestinal inflammation progression in broilers.
Topics: Animal Feed; Animals; Anti-Inflammatory Agents; Butyric Acid; Chickens; Dextran Sulfate; Diet; Dieta | 2019 |
Propionic Acid Induces Gliosis and Neuro-inflammation through Modulation of PTEN/AKT Pathway in Autism Spectrum Disorder.
Topics: Autism Spectrum Disorder; Biomarkers, Tumor; Butyric Acid; Cell Differentiation; Cell Proliferation; | 2019 |
Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet.
Topics: Adipose Tissue; Amides; Animals; Butyric Acid; Diet, High-Fat; Disease Models, Animal; Enzyme Activa | 2013 |
Sodium butyrate protects against severe burn-induced remote acute lung injury in rats.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Burns; Butyric Acid; Female; Granulocyte C | 2013 |
Effects of Lactobacillus plantarum 2142 and sodium n-butyrate in lipopolysaccharide-triggered inflammation: comparison of a porcine intestinal epithelial cell line and primary hepatocyte monocultures with a porcine enterohepatic co-culture system.
Topics: Animals; Butyric Acid; Cell Line; Coculture Techniques; Cytokines; Epithelial Cells; Gene Expression | 2014 |
Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress.
Topics: Animals; Arginine; Butyric Acid; Down-Regulation; Fibrosis; Inflammation; Nitric Oxide Synthase Type | 2015 |
Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway.
Topics: Adipocytes; Animals; Anti-Inflammatory Agents; Butyric Acid; Carrier Proteins; Disease Models, Anima | 2015 |
Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice.
Topics: Animals; Biomarkers; Blood Pressure; Butyric Acid; Cytokines; Diastole; Haplotypes; Heart; Hypertrop | 2016 |
Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells.
Topics: Apoptosis; Butyric Acid; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Epithelia | 2016 |
Intestinal alkaline phosphatase and sodium butyrate may be beneficial in attenuating LPS-induced intestinal inflammation.
Topics: Alkaline Phosphatase; Animals; Butyric Acid; Cattle; Gene Expression Regulation, Enzymologic; Inflam | 2016 |
Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid.
Topics: Animals; Apoptosis; Butyric Acid; Caspase 8; Cell Division; Cell Survival; Cytokines; DNA Damage; Fi | 2017 |
Comparison of three different application routes of butyrate to improve colonic anastomotic strength in rats.
Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Butyric Acid; Collagen; Colon; Drug Administration | 2017 |
Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier.
Topics: Animals; Butyric Acid; Cytokines; Diet, High-Fat; Drug Evaluation, Preclinical; Dysbiosis; Gastroint | 2017 |
Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins.
Topics: 3T3-L1 Cells; Animals; Butyric Acid; Crystallography, X-Ray; Drug Evaluation, Preclinical; Fatty Aci | 2009 |
[Protective effects of sodium butyrate against lung injury in mice with endotoxemia].
Topics: Animals; Butyric Acid; Endotoxemia; Inflammation; Interleukin-6; Lipopolysaccharides; Lung; Lung Inj | 2012 |