Page last updated: 2024-10-16

butyric acid and Innate Inflammatory Response

butyric acid has been researched along with Innate Inflammatory Response in 72 studies

Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.

Research Excerpts

ExcerptRelevanceReference
"This study suggests that maternal melatonin supplementation can shape the gut microbiota and metabolism of offspring under normal physiological conditions and protect them against LPS-induced inflammation in early life."8.31Maternal melatonin supplementation shapes gut microbiota and protects against inflammation in early life. ( Cai, Y; Feng, Z; Hao, H; Ke, Q; Lai, J; Li, F; Li, S; Liu, X; Lu, Z; Ma, F; Xiao, X, 2023)
"This is the first report where intranasal curcumin inhibited asthma severity via affecting HDAC 1 (H3acK9) leading to NF-kB suppression in mouse model of allergic asthma."8.12Intranasal curcumin and sodium butyrate modulates airway inflammation and fibrosis via HDAC inhibition in allergic asthma. ( Dash, D; Islam, R; Singh, R, 2022)
" The present study aimed to evaluate the protective effect of SB against L-arginine (L-Arg)-induced pancreatic fibrosis in Wistar rats."7.81Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. ( Jena, G; Kanika, G; Khan, S, 2015)
"Butyric acid treatment increased HuR expression in both cytoplasm and nucleus and decreased the level of p-AMPK and p-ACC, while transfection of AMPK activator or HuR-siRNA would down-regulate HuR expression."5.62Butyric acid alleviated chronic intermittent hypoxia-induced lipid formation and inflammation through up-regulating HuR expression and inactivating AMPK pathways. ( Abdullahi, R; He, Y; Huang, N; Ren, X; Su, M; Xu, M; Xue, S; Yu, J, 2021)
"Humic acid (MFG) and fat-protected butyric acid (BA) has been shown to modulate energy metabolism and inflammation."5.19Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs. ( Edmonds, MS; Gabler, NK; Johal, S; Kerr, BJ; Moreland, S; van Sambeek, DM; Weber, TE, 2014)
"This study suggests that maternal melatonin supplementation can shape the gut microbiota and metabolism of offspring under normal physiological conditions and protect them against LPS-induced inflammation in early life."4.31Maternal melatonin supplementation shapes gut microbiota and protects against inflammation in early life. ( Cai, Y; Feng, Z; Hao, H; Ke, Q; Lai, J; Li, F; Li, S; Liu, X; Lu, Z; Ma, F; Xiao, X, 2023)
"This is the first report where intranasal curcumin inhibited asthma severity via affecting HDAC 1 (H3acK9) leading to NF-kB suppression in mouse model of allergic asthma."4.12Intranasal curcumin and sodium butyrate modulates airway inflammation and fibrosis via HDAC inhibition in allergic asthma. ( Dash, D; Islam, R; Singh, R, 2022)
" Treatment should be aimed at possible causes of intestinal damage (Clostridioides difficile), as well as reducing inflammation, restoring intestinal permeability, cytoprotection of mucosal cells, replenishing butyric acid deficiency."4.12[Features of the intestine conditions at patients with a new coronavirus infection]. ( Ardatskaya, MD; Butorova, LI; Topchiy, TВ; Мinushkin, ОN; Маslovskii, LV, 2022)
" Liver damage, markers of glucose metabolism, inflammation, intestinal barrier function and melatonin metabolism were determined."3.96Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis. ( Baumann, A; Bergheim, I; Brandt, A; Burkard, M; Jin, CJ; Nier, A; Sellmann, C; Venturelli, S, 2020)
" The present study is aimed at testing the hypothesis that resistant maltodextrin (RM), a soluble dietary fiber produced by starch debranching, alleviated dextran sulfate sodium- (DSS-) induced colitis in mice."3.96Resistant Maltodextrin Alleviates Dextran Sulfate Sodium-Induced Intestinal Inflammatory Injury by Increasing Butyric Acid to Inhibit Proinflammatory Cytokine Levels. ( Han, D; Huang, S; Pang, J; Wang, J; Wang, S; Wu, Y; Wu, Z; Zhang, S, 2020)
" The present study aimed to evaluate the protective effect of SB against L-arginine (L-Arg)-induced pancreatic fibrosis in Wistar rats."3.81Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress. ( Jena, G; Kanika, G; Khan, S, 2015)
"Chronic low-grade inflammation is regarded to an important signature of atherosclerosis (AS)."1.91Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE-/- mice. ( Bai, Z; Guo, M; Jia, S; Jiang, X; Li, A; Li, Y; Liu, Y; Ma, H; Ma, P; Ren, Y; Wang, H; Wang, R; Wang, T; Yan, R; Yang, L; Zhang, P; Zhang, Q; Zhang, X, 2023)
"We induced ulcerative colitis (UC) in mice utilizing dextran sodium sulfate (DSS) in the drinking water for 7 days."1.91Sodium Butyrate Protects Against Intestinal Oxidative Damage and Neuroinflammation in the Prefrontal Cortex of Ulcerative Colitis Mice Model. ( De Oliveira, J; do Nascimento, ND; Fröhlich, NT; Gelain, DP; Gomes, HM; Kessler, F; Martins, A; Moreira, JCF; Paz, AH; Possa, L; Rodrigues, MS; Santos, L; Silveira, AK; Sirena, D, 2023)
"The onset and progression of COPD are affected by multiple environmental and genetic risk factors, such as inflammatory mechanisms, oxidative stress, and an imbalance between proteinase and antiprotease."1.91Sodium butyrate (SB) ameliorated inflammation of COPD induced by cigarette smoke through activating the GPR43 to inhibit NF-κB/MAPKs signaling pathways. ( Jia, W; Kang, Y; Li, Q; Qiu, Z; Tong, Y; Wang, P; Wu, G; Xu, C; Zhao, Z, 2023)
"Burns are a common traumatic injuries with considerable morbidity and mortality rates."1.72Combination of sodium butyrate and probiotics ameliorates severe burn-induced intestinal injury by inhibiting oxidative stress and inflammatory response. ( Gao, Y; He, Q; Shen, G; Wang, H; Wang, L; Yan, Z; Zhou, B, 2022)
"However, the role of butyrate in overnutrition-induced microglial activation and hypothalamic inflammation remains unclear."1.72Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation. ( Chen, T; Duan, C; Ge, X; Guo, K; Li, Y; Liu, H; Lu, H; Shang, Y; Wang, X; Zhang, D, 2022)
" C4 dose-response experiments in the presence or absence of cytokines were performed in a co-culture system including Caco-2 cells, HepG2 cells, or both."1.62Butyric Acid Added Apically to Intestinal Caco-2 Cells Elevates Hepatic ApoA-I Transcription and Rescues Lower ApoA-I Expression in Inflamed HepG2 Cells Co-Cultured in the Basolateral Compartment. ( Mensink, RP; Plat, J; Popeijus, HE; Tayyeb, JZ, 2021)
"Current strategies for the treatment of Alzheimer's disease (AD) focus on the pathology in the later stages of disease progression."1.62Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice. ( Jiang, Y; Li, K; Li, X; Xu, L; Yang, Z, 2021)
"Butyric acid treatment increased HuR expression in both cytoplasm and nucleus and decreased the level of p-AMPK and p-ACC, while transfection of AMPK activator or HuR-siRNA would down-regulate HuR expression."1.62Butyric acid alleviated chronic intermittent hypoxia-induced lipid formation and inflammation through up-regulating HuR expression and inactivating AMPK pathways. ( Abdullahi, R; He, Y; Huang, N; Ren, X; Su, M; Xu, M; Xue, S; Yu, J, 2021)
"Depression is a common disease that afflicts one in 6 people."1.56Lipopolysaccharide-Induced Depression-Like Behaviors Is Ameliorated by Sodium Butyrate via Inhibiting Neuroinflammation and Oxido-Nitrosative Stress. ( Chen, J; Chen, Z; He, H; Huang, C; Li, Y; Liu, R; Ma, Y; Qiu, J; Tong, L; You, Q, 2020)
"Butyrate might thus be valuable in the treatment of sepsis, in which inhibition of overwhelming cytokine release is vitally important."1.51Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis. ( Fu, J; Li, G; Wu, X; Zang, B, 2019)
"Butyric acid is a beneficial feed additive used in animal production, including poultry production."1.51Effects of sodium butyrate on intestinal health and gut microbiota composition during intestinal inflammation progression in broilers. ( Ji, J; Li, Y; Liu, TF; Luo, CL; Qu, H; Shu, DM; Wang, J; Wang, Y; Zou, X, 2019)
"Despite extensive research, anastomotic leakage (AL) remains one of the most dreaded complications after colorectal surgery."1.46Comparison of three different application routes of butyrate to improve colonic anastomotic strength in rats. ( Boonen, BT; Bosmans, JW; Bouvy, ND; Gijbels, MJ; Jongen, AC; Marsich, E; Scognamiglio, F; Stucchi, L; van Rijn, S, 2017)
"Nonalcoholic fatty liver disease (NAFLD) is the most common form of chronic liver disease."1.39Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet. ( Calignano, A; Canani, RB; Ferrante, MC; Iacono, A; Mattace Raso, G; Meli, R; Paciello, O; Russo, R; Santoro, A; Simeoli, R, 2013)

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (1.39)18.2507
2000's1 (1.39)29.6817
2010's26 (36.11)24.3611
2020's44 (61.11)2.80

Authors

AuthorsStudies
Deng, M2
Wu, X2
Duan, X1
Xu, J1
Yang, X1
Sheng, X1
Lou, P1
Shao, C1
Lv, C1
Yu, Z1
Islam, R1
Dash, D1
Singh, R1
Bayazid, AB2
Kim, JG2
Azam, S1
Jeong, SA1
Kim, DH1
Park, CW1
Lim, BO2
Zhou, B1
Wang, L1
Gao, Y1
He, Q1
Yan, Z1
Wang, H4
Shen, G1
Dou, X1
Yan, D1
Ma, Z1
Gao, N1
Shan, A1
Ortiz, AM1
Simpson, J1
Langner, CA1
Baker, PJ1
Aguilar, C1
Brooks, K1
Flynn, JK1
Vinton, CL1
Rahmberg, AR1
Hickman, HD1
Brenchley, JM1
Ali, I1
Li, C2
Kuang, M1
Shah, AU1
Shafiq, M1
Ahmad, MA1
Abdalmegeed, D1
Li, L1
Wang, G1
Kaya-Sezginer, E1
Yilmaz-Oral, D1
Kırlangıç, OF1
Yilmaz, S1
Özen, FZ1
Aşan, M1
Gur, S1
Zhou, T1
Xu, H2
Cheng, X1
He, Y2
Ren, Q1
Li, D1
Xie, Y2
Gao, C1
Zhang, Y4
Sun, X2
Xu, Y1
Huang, W1
Wang, X2
Duan, C1
Li, Y5
Lu, H1
Guo, K1
Ge, X1
Chen, T1
Shang, Y1
Liu, H1
Zhang, D1
Topchiy, TВ1
Ardatskaya, MD1
Butorova, LI1
Маslovskii, LV1
Мinushkin, ОN1
Gao, L1
Davies, DL1
Asatryan, L1
Yan, M1
Li, X2
Sun, C1
Tan, J1
Liu, Y4
Li, M1
Qi, Z1
He, J1
Wang, D1
Wu, L1
Choi, Y1
Choi, SI1
Kim, N1
Nam, RH1
Jang, JY1
Na, HY1
Shin, CM1
Lee, DH1
Min, H1
Kim, YR1
Seok, YJ1
Guo, TT1
Zhang, Z1
Sun, Y1
Zhu, RY1
Wang, FX1
Ma, LJ1
Jiang, L1
Liu, HD1
Ma, H1
Yang, L1
Yan, R1
Wang, R1
Zhang, P1
Bai, Z1
Ren, Y1
Jiang, X1
Wang, T2
Ma, P1
Zhang, Q1
Li, A1
Guo, M1
Zhang, X2
Jia, S1
Haskey, N1
Estaki, M1
Ye, J1
Shim, RK1
Singh, S1
Dieleman, LA1
Jacobson, K1
Gibson, DL1
Liu, K1
He, X1
Huang, J2
Yu, S1
Cui, M1
Gao, M2
Liu, L1
Qian, Y1
Hui, M1
Hong, Y1
Nie, X1
Li, F1
Lai, J1
Ma, F1
Cai, Y1
Li, S1
Feng, Z1
Lu, Z1
Liu, X1
Ke, Q1
Hao, H1
Xiao, X1
Ikeda, Y1
Matsuda, S1
Zong, Q1
Li, K2
Qu, H2
Hu, P1
Xu, C3
Wu, S1
Wang, S2
Liu, HY1
Cai, D1
Bao, W1
Silveira, AK1
Gomes, HM1
Fröhlich, NT1
Possa, L1
Santos, L1
Kessler, F1
Martins, A1
Rodrigues, MS1
De Oliveira, J1
do Nascimento, ND1
Sirena, D1
Paz, AH1
Gelain, DP1
Moreira, JCF1
Zhao, Z1
Tong, Y1
Kang, Y1
Qiu, Z1
Li, Q1
Wu, G1
Jia, W1
Wang, P2
Keshari, S1
Balasubramaniam, A1
Myagmardoloonjin, B1
Herr, DR1
Negari, IP1
Huang, CM1
Lewis, G1
Wang, B1
Shafiei Jahani, P1
Hurrell, BP1
Banie, H1
Aleman Muench, GR1
Maazi, H1
Helou, DG1
Howard, E1
Galle-Treger, L1
Lo, R1
Santosh, S1
Baltus, A1
Bongers, G1
San-Mateo, L1
Gilliland, FD1
Rehan, VK1
Soroosh, P1
Akbari, O1
Busbee, PB1
Menzel, L1
Alrafas, HR1
Dopkins, N1
Becker, W1
Miranda, K1
Tang, C1
Chatterjee, S1
Singh, U1
Nagarkatti, M1
Nagarkatti, PS1
Anderson, G1
Maes, M1
de Lazari, MGT1
Pereira, LX1
Orellano, LAA1
Scheuermann, K1
Machado, CT1
Vasconcelos, AC1
Andrade, SP1
Campos, PP1
Qiu, J1
Liu, R1
Ma, Y1
Chen, Z3
He, H1
Chen, J1
Tong, L1
Huang, C2
You, Q1
Baumann, A1
Jin, CJ1
Brandt, A1
Sellmann, C1
Nier, A1
Burkard, M1
Venturelli, S1
Bergheim, I1
Qu, F1
Chen, L1
Liu, C2
Zhang, M1
Ren, F1
Guo, H1
Zhang, H1
Ge, S1
Wu, C1
Zhao, L1
Roshanravan, N1
Alamdari, NM1
Jafarabadi, MA1
Mohammadi, A1
Shabestari, BR1
Nasirzadeh, N1
Asghari, S1
Mansoori, B1
Akbarzadeh, M1
Ghavami, A1
Ghaffari, S1
Ostadrahimi, A1
Qiao, CM1
Sun, MF1
Jia, XB1
Zhang, BP1
Zhao, LP1
Shi, Y1
Zhou, ZL1
Zhu, YL1
Cui, C1
Shen, YQ1
Luo, S1
Jiang, C1
Tang, Y1
Cao, Z1
Jia, H1
Xu, Q1
Zhao, C1
Loor, JJ1
Zhang, S1
Huang, S1
Wu, Z1
Pang, J1
Wu, Y2
Wang, J3
Han, D1
Luzardo-Ocampo, I1
Loarca-Piña, G1
Gonzalez de Mejia, E1
Yang, T1
Yang, H1
Heng, C1
Chen, S1
Hu, Y1
Jiang, Z1
Yu, Q1
Wang, Z1
Qian, S1
Du, L1
Lu, Q1
Yin, X1
Pla, R1
Pujos-Guillot, E1
Durand, S1
Brandolini-Bunlon, M1
Centeno, D1
Pyne, DB1
Toussaint, JF1
Hellard, P1
Tayyeb, JZ1
Popeijus, HE1
Mensink, RP1
Plat, J1
Huang, Y1
Ding, Y1
Shen, C1
Chen, X2
Jiang, Y1
Xu, L1
Yang, Z1
Su, M1
Xue, S1
Yu, J1
Ren, X1
Huang, N1
Abdullahi, R1
Xu, M1
Zhou, Q1
Gu, R1
Xue, B1
Li, P1
Gu, Q1
Jang, YA1
Kim, YM1
Liu, FY1
Wen, J1
Hou, J1
Zhang, SQ1
Sun, CB1
Zhou, LC1
Yin, W1
Pang, WL1
Wang, C1
Ying, Y1
Han, SS1
Yan, JY1
Li, CX1
Yuan, JL1
Xing, HJ1
Yang, ZS1
Liu, J2
Chang, G2
Ma, N2
Wang, Y4
Roy, AC2
Shen, X2
Zhou, D2
Pan, Q2
Shen, F1
Cao, HX1
Ding, WJ1
Chen, YW2
Fan, JG2
Wang, JJ1
Wei, ZK1
Wang, YN1
Fu, YH1
Yang, ZT1
Gong, Y1
Yang, R1
Hu, W1
Xu, X1
Qin, Y1
Lanza, M1
Campolo, M1
Casili, G1
Filippone, A1
Paterniti, I1
Cuzzocrea, S1
Esposito, E1
Dai, J1
Yang, P1
Xu, W1
Ai, Q1
Zhang, W1
Mai, K1
Fu, J1
Li, G1
Zang, B1
Roy, S1
Aabdin, ZU1
Fang, W1
Xue, H1
Chen, K1
Ling, W1
Zou, X1
Ji, J1
Shu, DM1
Liu, TF1
Luo, CL1
Abdelli, LS1
Samsam, A1
Naser, SA1
Mattace Raso, G1
Simeoli, R1
Russo, R1
Iacono, A1
Santoro, A1
Paciello, O1
Ferrante, MC1
Canani, RB1
Calignano, A1
Meli, R1
Liang, X1
Wang, RS1
Wang, F1
Liu, S1
Guo, F1
Sun, L1
Wang, YJ1
Sun, YX1
Chen, XL1
Farkas, O1
Mátis, G1
Pászti-Gere, E1
Palócz, O1
Kulcsár, A1
Petrilla, J1
Csikó, G1
Neogrády, Z1
Gálfi, P1
Weber, TE1
van Sambeek, DM1
Gabler, NK1
Kerr, BJ1
Moreland, S1
Johal, S1
Edmonds, MS1
Kanika, G1
Khan, S1
Jena, G1
He, G1
Peng, Y1
Zhong, W1
Zhang, B1
Subramanian, U1
Kumar, P1
Mani, I1
Chen, D1
Kessler, I1
Periyasamy, R1
Raghavaraju, G1
Pandey, KN1
Reijnders, D1
Goossens, GH1
Hermes, GD1
Neis, EP1
van der Beek, CM1
Most, J1
Holst, JJ1
Lenaerts, K1
Kootte, RS1
Nieuwdorp, M1
Groen, AK1
Olde Damink, SW1
Boekschoten, MV1
Smidt, H1
Zoetendal, EG1
Dejong, CH1
Blaak, EE1
Astakhova, L1
Ngara, M1
Babich, O1
Prosekov, A1
Asyakina, L1
Dyshlyuk, L1
Midtvedt, T1
Zhou, X1
Ernberg, I1
Matskova, L1
Melo, AD1
Silveira, H1
Bortoluzzi, C1
Lara, LJ1
Garbossa, CA1
Preis, G1
Costa, LB1
Rostagno, MH1
Shirasugi, M1
Nishioka, K1
Yamamoto, T1
Nakaya, T1
Kanamura, N1
Bosmans, JW1
Jongen, AC1
Boonen, BT1
van Rijn, S1
Scognamiglio, F1
Stucchi, L1
Gijbels, MJ1
Marsich, E1
Bouvy, ND1
Xin, FZ1
Zhang, RN1
He, CX1
Chen, GY1
Hertzel, AV1
Hellberg, K1
Reynolds, JM1
Kruse, AC1
Juhlmann, BE1
Smith, AJ1
Sanders, MA1
Ohlendorf, DH1
Suttles, J1
Bernlohr, DA1
Zeng, T1
Zhang, L1
Wischmeyer, P1
Pemberton, JH1
Phillips, SF1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Microbiome Reprogramming on Liver Fat Accumulation[NCT03914495]57 participants (Actual)Interventional2019-05-21Terminated (stopped due to PI carefully considered multiple factors and decided to close study to any further enrollment.)
Effects of 3-month Probiotic Mix Supplementation (L. Helveticus R-0052, B. Longum R-0175) on Gut Microbiota and Metabolome, Endocannabinoid and Immune Systems Activation, Along With Symptoms of Fatigue in Professional Dancers[NCT05567653]60 participants (Anticipated)Interventional2022-09-21Recruiting
A Pilot Study of the Safety and Efficacy of AST-120 in the Treatment of Antibiotic-Refractory Pouchitis[NCT00583531]Phase 22 participants (Actual)Interventional2007-03-31Terminated (stopped due to Lack of enrollment)
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for butyric acid and Innate Inflammatory Response

ArticleYear
Gut Dysbiosis Dysregulates Central and Systemic Homeostasis via Suboptimal Mitochondrial Function: Assessment, Treatment and Classification Implications.
    Current topics in medicinal chemistry, 2020, Volume: 20, Issue:7

    Topics: Butyric Acid; Cell Line; Dysbiosis; Gastrointestinal Microbiome; Homeostasis; Humans; Immune System;

2020

Trials

5 trials available for butyric acid and Innate Inflammatory Response

ArticleYear
A Mediterranean Diet Pattern Improves Intestinal Inflammation Concomitant with Reshaping of the Bacteriome in Ulcerative Colitis: A Randomised Controlled Trial.
    Journal of Crohn's & colitis, 2023, Nov-08, Volume: 17, Issue:10

    Topics: Adult; Butyric Acid; Canada; Colitis, Ulcerative; Diet, Mediterranean; Feces; Female; Humans; Inflam

2023
Effects of oral butyrate and inulin supplementation on inflammation-induced pyroptosis pathway in type 2 diabetes: A randomized, double-blind, placebo-controlled trial.
    Cytokine, 2020, Volume: 131

    Topics: Administration, Oral; Adult; Antioxidants; Butyric Acid; Diabetes Mellitus, Type 2; Dietary Suppleme

2020
Effects of dietary humic and butyric acid on growth performance and response to lipopolysaccharide in young pigs.
    Journal of animal science, 2014, Volume: 92, Issue:9

    Topics: Animals; Butyric Acid; Cytokines; Dietary Fats; Escherichia coli; Humic Substances; Inflammation; In

2014
Effects of Gut Microbiota Manipulation by Antibiotics on Host Metabolism in Obese Humans: A Randomized Double-Blind Placebo-Controlled Trial.
    Cell metabolism, 2016, 07-12, Volume: 24, Issue:1

    Topics: Adipocytes; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Biomarkers; Butyric Acid; Cell Shape; D

2016
Chronic pouchitis after ileal pouch-anal anastomosis: responses to butyrate and glutamine suppositories in a pilot study.
    Mayo Clinic proceedings, 1993, Volume: 68, Issue:10

    Topics: Adolescent; Adult; Butyrates; Butyric Acid; Chronic Disease; Fatty Acids, Volatile; Feces; Female; G

1993

Other Studies

66 other studies available for butyric acid and Innate Inflammatory Response

ArticleYear
    Food & function, 2021, Nov-01, Volume: 12, Issue:21

    Topics: Animals; Anti-Inflammatory Agents; Butyrates; Butyric Acid; Colitis; Dextran Sulfate; Female; Gene E

2021
Intranasal curcumin and sodium butyrate modulates airway inflammation and fibrosis via HDAC inhibition in allergic asthma.
    Cytokine, 2022, Volume: 149

    Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid;

2022
Sodium butyrate ameliorates neurotoxicity and exerts anti-inflammatory effects in high fat diet-fed mice.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2022, Volume: 159

    Topics: Animals; Anti-Inflammatory Agents; Body Weight; Brain; Butyric Acid; Diet, High-Fat; Inflammation; M

2022
Combination of sodium butyrate and probiotics ameliorates severe burn-induced intestinal injury by inhibiting oxidative stress and inflammatory response.
    Burns : journal of the International Society for Burn Injuries, 2022, Volume: 48, Issue:5

    Topics: Animals; Burns; Butyric Acid; Inflammation; NF-E2-Related Factor 2; NF-kappa B; Oxidative Stress; Pr

2022
Sodium butyrate alleviates LPS-induced kidney injury via inhibiting TLR2/4 to regulate rBD2 expression.
    Journal of food biochemistry, 2022, Volume: 46, Issue:7

    Topics: Animals; beta-Defensins; Butyric Acid; Inflammation; Kidney; Lipopolysaccharides; Rats; RNA, Messeng

2022
Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques.
    Scientific reports, 2022, 05-06, Volume: 12, Issue:1

    Topics: Animals; Anti-Retroviral Agents; Butyric Acid; HIV Infections; Humans; Immune Reconstitution; Inflam

2022
Nrf2 Activation and NF-Kb & caspase/bax signaling inhibition by sodium butyrate alleviates LPS-induced cell injury in bovine mammary epithelial cells.
    Molecular immunology, 2022, Volume: 148

    Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Butyric Acid; Caspases; Cattle; Epithelial Cells; Fe

2022
Sodium butyrate ameliorates erectile dysfunction through fibrosis in a rat model of partial bladder outlet obstruction.
    Andrology, 2022, Volume: 10, Issue:7

    Topics: Animals; Butyric Acid; Disease Models, Animal; Erectile Dysfunction; Fibrosis; Histone Deacetylases;

2022
Sodium Butyrate Attenuates Diabetic Kidney Disease Partially via Histone Butyrylation Modification.
    Mediators of inflammation, 2022, Volume: 2022

    Topics: Butyric Acid; Diabetes Mellitus; Diabetic Nephropathies; Histones; Humans; Inflammation; Protein Pro

2022
Sodium butyrate reduces overnutrition-induced microglial activation and hypothalamic inflammation.
    International immunopharmacology, 2022, Volume: 111

    Topics: Animals; Butyric Acid; Diet, High-Fat; Hypothalamus; Inflammation; Mice; Mice, Inbred C57BL; Microgl

2022
[Features of the intestine conditions at patients with a new coronavirus infection].
    Terapevticheskii arkhiv, 2022, Aug-12, Volume: 94, Issue:7

    Topics: Butyric Acid; COVID-19; Diarrhea; Humans; Inflammation; Intestines; SARS-CoV-2

2022
Sodium Butyrate Supplementation Modulates Neuroinflammatory Response Aggravated by Antibiotic Treatment in a Mouse Model of Binge-like Ethanol Drinking.
    International journal of molecular sciences, 2022, Dec-10, Volume: 23, Issue:24

    Topics: Alcohol Drinking; Alcoholism; Animals; Anti-Bacterial Agents; Butyric Acid; Cytokines; Dietary Suppl

2022
Sodium Butyrate Attenuates AGEs-Induced Oxidative Stress and Inflammation by Inhibiting Autophagy and Affecting Cellular Metabolism in THP-1 Cells.
    Molecules (Basel, Switzerland), 2022, Dec-09, Volume: 27, Issue:24

    Topics: Butyric Acid; Glycation End Products, Advanced; Humans; Inflammasomes; Inflammation; NF-kappa B; NLR

2022
Effect of Clostridium butyricum on High-Fat Diet-Induced Intestinal Inflammation and Production of Short-Chain Fatty Acids.
    Digestive diseases and sciences, 2023, Volume: 68, Issue:6

    Topics: Animals; Butyric Acid; Clostridium butyricum; Diet, High-Fat; Fatty Acids, Volatile; Female; Inflamm

2023
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
    Nutrients, 2023, Feb-13, Volume: 15, Issue:4

    Topics: Animals; Butyric Acid; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation;

2023
Butyrate suppresses atherosclerotic inflammation by regulating macrophages and polarization via GPR43/HDAC-miRNAs axis in ApoE-/- mice.
    PloS one, 2023, Volume: 18, Issue:3

    Topics: Animals; Apolipoproteins E; Atherosclerosis; Butyric Acid; Inflammation; Macrophages; Mice; Mice, In

2023
Short-chain fatty acid-butyric acid ameliorates granulosa cells inflammation through regulating METTL3-mediated N6-methyladenosine modification of FOSL2 in polycystic ovarian syndrome.
    Clinical epigenetics, 2023, 05-13, Volume: 15, Issue:1

    Topics: Animals; Butyric Acid; DNA Methylation; Fatty Acids, Volatile; Female; Fos-Related Antigen-2; Granul

2023
Maternal melatonin supplementation shapes gut microbiota and protects against inflammation in early life.
    International immunopharmacology, 2023, Volume: 120

    Topics: Animals; Butyric Acid; Dietary Supplements; Fatty Acids, Volatile; Female; Gastrointestinal Microbio

2023
Gut Protective Effect from D-Methionine or Butyric Acid against DSS and Carrageenan-Induced Ulcerative Colitis.
    Molecules (Basel, Switzerland), 2023, May-28, Volume: 28, Issue:11

    Topics: Animals; Butyric Acid; Carrageenan; Colitis; Colitis, Ulcerative; Dextran Sulfate; Disease Models, A

2023
Sodium Butyrate Ameliorates Deoxynivalenol-Induced Oxidative Stress and Inflammation in the Porcine Liver via NR4A2-Mediated Histone Acetylation.
    Journal of agricultural and food chemistry, 2023, Jul-12, Volume: 71, Issue:27

    Topics: Acetylation; Animals; Butyric Acid; Chemical and Drug Induced Liver Injury, Chronic; Histones; Infla

2023
Sodium Butyrate Protects Against Intestinal Oxidative Damage and Neuroinflammation in the Prefrontal Cortex of Ulcerative Colitis Mice Model.
    Immunological investigations, 2023, Volume: 52, Issue:7

    Topics: Animals; Butyric Acid; Claudin-5; Colitis, Ulcerative; Disease Models, Animal; Inflammation; Inflamm

2023
Sodium butyrate (SB) ameliorated inflammation of COPD induced by cigarette smoke through activating the GPR43 to inhibit NF-κB/MAPKs signaling pathways.
    Molecular immunology, 2023, Volume: 163

    Topics: Animals; Anti-Inflammatory Agents; Butyric Acid; Cigarette Smoking; Inflammation; Interleukin-6; MAP

2023
Butyric Acid from Probiotic
    International journal of molecular sciences, 2019, Sep-11, Volume: 20, Issue:18

    Topics: Acetolactate Synthase; Animals; Butyric Acid; Down-Regulation; Fatty Acids, Volatile; Female; Fermen

2019
Dietary Fiber-Induced Microbial Short Chain Fatty Acids Suppress ILC2-Dependent Airway Inflammation.
    Frontiers in immunology, 2019, Volume: 10

    Topics: Animals; Asthma; Butyric Acid; Dietary Fiber; Gastrointestinal Microbiome; Immunity, Innate; Inflamm

2019
Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner.
    JCI insight, 2020, 01-16, Volume: 5, Issue:1

    Topics: Animals; Butyric Acid; Colitis; Colon; Disease Models, Animal; Dysbiosis; Female; Gastrointestinal M

2020
Sodium Butyrate Downregulates Implant-Induced Inflammation in Mice.
    Inflammation, 2020, Volume: 43, Issue:4

    Topics: Animals; Butyric Acid; Down-Regulation; Ethers; Histamine Antagonists; Inflammation; Inflammation Me

2020
Lipopolysaccharide-Induced Depression-Like Behaviors Is Ameliorated by Sodium Butyrate via Inhibiting Neuroinflammation and Oxido-Nitrosative Stress.
    Pharmacology, 2020, Volume: 105, Issue:9-10

    Topics: Animals; Antidepressive Agents; Behavior, Animal; Butyric Acid; Cytokines; Depression; Disease Model

2020
Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis.
    Nutrients, 2020, Mar-30, Volume: 12, Issue:4

    Topics: Animals; Butyric Acid; Cholesterol, Dietary; Diet, High-Fat; Dietary Supplements; Disease Models, An

2020
SCFAs alleviated steatosis and inflammation in mice with NASH induced by MCD.
    The Journal of endocrinology, 2020, Volume: 245, Issue:3

    Topics: Acetates; Alanine Transaminase; Animals; Aspartate Aminotransferases; Butyrates; Butyric Acid; Fatty

2020
Sodium Butyrate Exacerbates Parkinson's Disease by Aggravating Neuroinflammation and Colonic Inflammation in MPTP-Induced Mice Model.
    Neurochemical research, 2020, Volume: 45, Issue:9

    Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Astrocytes; Butyric Acid; Cell Line; Colon; C

2020
Sodium butyrate reduces bovine mammary epithelial cell inflammatory responses induced by exogenous lipopolysaccharide, by inactivating NF-κB signaling.
    Journal of dairy science, 2020, Volume: 103, Issue:9

    Topics: Animals; Butyric Acid; Cattle; Epithelial Cells; Female; Inflammation; Lipopolysaccharides; Mammary

2020
Resistant Maltodextrin Alleviates Dextran Sulfate Sodium-Induced Intestinal Inflammatory Injury by Increasing Butyric Acid to Inhibit Proinflammatory Cytokine Levels.
    BioMed research international, 2020, Volume: 2020

    Topics: Animals; Butyric Acid; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Feces; Fe

2020
Gallic and butyric acids modulated NLRP3 inflammasome markers in a co-culture model of intestinal inflammation.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2020, Volume: 146

    Topics: Biomarkers; Butyric Acid; Caco-2 Cells; Cell Differentiation; Cell Survival; Coculture Techniques; C

2020
Amelioration of non-alcoholic fatty liver disease by sodium butyrate is linked to the modulation of intestinal tight junctions in db/db mice.
    Food & function, 2020, Dec-01, Volume: 11, Issue:12

    Topics: Animals; Blood Glucose; Butyric Acid; Caco-2 Cells; Cholesterol; Clostridium butyricum; Colon; Cytok

2020
Non-targeted metabolomics analyses by mass spectrometry to explore metabolic stress after six training weeks in high level swimmers.
    Journal of sports sciences, 2021, Volume: 39, Issue:9

    Topics: Adolescent; Athletes; Butyric Acid; Carnitine; Cresols; Cross-Over Studies; Fatigue; Female; Glycoge

2021
Butyric Acid Added Apically to Intestinal Caco-2 Cells Elevates Hepatic ApoA-I Transcription and Rescues Lower ApoA-I Expression in Inflamed HepG2 Cells Co-Cultured in the Basolateral Compartment.
    Biomolecules, 2021, 01-07, Volume: 11, Issue:1

    Topics: Apolipoprotein A-I; Butyric Acid; Caco-2 Cells; Coculture Techniques; Hep G2 Cells; Humans; Inflamma

2021
Effects of sodium butyrate supplementation on inflammation, gut microbiota, and short-chain fatty acids in Helicobacter pylori-infected mice.
    Helicobacter, 2021, Volume: 26, Issue:2

    Topics: Animals; Butyric Acid; Dietary Supplements; Fatty Acids, Volatile; Gastrointestinal Microbiome; Heli

2021
Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice.
    Chemico-biological interactions, 2021, May-25, Volume: 341

    Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Butyric Acid; Cognitive Dysfunction; Disea

2021
Butyric acid alleviated chronic intermittent hypoxia-induced lipid formation and inflammation through up-regulating HuR expression and inactivating AMPK pathways.
    Bioscience reports, 2021, 06-25, Volume: 41, Issue:6

    Topics: Adipocytes; AMP-Activated Protein Kinases; Anti-Inflammatory Agents; Apoptosis; Apoptosis Regulatory

2021
Phenyl lactic acid alleviates
    Food & function, 2021, Jun-21, Volume: 12, Issue:12

    Topics: Animals; Anti-Inflammatory Agents; Butyric Acid; Colitis; Colon; Cytokines; Dysbiosis; Female; Gastr

2021
Neuroprotective Effects of Sodium Butyrate through Suppressing Neuroinflammation and Modulating Antioxidant Enzymes.
    Neurochemical research, 2021, Volume: 46, Issue:9

    Topics: Apoptosis Regulatory Proteins; Butyric Acid; Cell Line, Tumor; Cell Survival; Cyclooxygenase 2; Glut

2021
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
    International immunopharmacology, 2021, Volume: 96

    Topics: Acetic Acid; Animals; Aorta; Atherosclerosis; Benzyl Alcohols; Butyric Acid; Disease Models, Animal;

2021
Sodium butyrate pretreatment mitigates lipopolysaccharide-induced inflammation through the TLR4/NF-κB signaling pathway in bovine embryo trachea cells.
    Animal biotechnology, 2022, Volume: 33, Issue:7

    Topics: Animals; Butyric Acid; Cattle; Cattle Diseases; Inflammation; Interleukin-6; Lipopolysaccharides; NF

2022
Total fecal microbiota transplantation alleviates high-fat diet-induced steatohepatitis in mice via beneficial regulation of gut microbiota.
    Scientific reports, 2017, 05-08, Volume: 7, Issue:1

    Topics: Adipose Tissue; Animals; Body Weight; Butyric Acid; Cecum; Diet, High-Fat; Endotoxemia; Epididymis;

2017
Butyrate protects against disruption of the blood-milk barrier and moderates inflammatory responses in a model of mastitis induced by lipopolysaccharide.
    British journal of pharmacology, 2017, Volume: 174, Issue:21

    Topics: Animals; Butyric Acid; Disease Models, Animal; Epithelial Cells; Female; Inflammation; Lipopolysacch

2017
Sodium butyrate triggers a functional elongation of microglial process via Akt-small RhoGTPase activation and HDACs inhibition.
    Neurobiology of disease, 2018, Volume: 111

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Butyric Acid; Cell Enlargement; Cells, Cultured; G

2018
Sodium Butyrate Exerts Neuroprotective Effects in Spinal Cord Injury.
    Molecular neurobiology, 2019, Volume: 56, Issue:6

    Topics: Animals; Antioxidants; Butyric Acid; Cyclooxygenase 2; Inflammation; Interleukin-1beta; Male; Mice;

2019
Sodium butyrate supplementation in high-soybean meal diets for turbot (Scophthalmus maximus L.): Effects on inflammatory status, mucosal barriers and microbiota in the intestine.
    Fish & shellfish immunology, 2019, Volume: 88

    Topics: Animal Feed; Animal Nutritional Physiological Phenomena; Animals; Aquaculture; Bacteria; Butyric Aci

2019
Sodium Butyrate Ameliorates Intestinal Injury and Improves Survival in a Rat Model of Cecal Ligation and Puncture-Induced Sepsis.
    Inflammation, 2019, Volume: 42, Issue:4

    Topics: Animals; Butyric Acid; Cecum; Inflammation; Intestinal Mucosa; Intestines; Ligation; NF-kappa B; Pun

2019
Sodium butyrate suppresses NOD1-mediated inflammatory molecules expressed in bovine hepatocytes during iE-DAP and LPS treatment.
    Journal of cellular physiology, 2019, Volume: 234, Issue:11

    Topics: Animals; Butyric Acid; Cattle; Diaminopimelic Acid; Hepatocytes; Inflammation; Ligands; Lipopolysacc

2019
Supplementation with Sodium Butyrate Modulates the Composition of the Gut Microbiota and Ameliorates High-Fat Diet-Induced Obesity in Mice.
    The Journal of nutrition, 2019, 05-01, Volume: 149, Issue:5

    Topics: Animals; Butyric Acid; Colon; Diet, High-Fat; Dietary Fats; Dietary Supplements; Dysbiosis; Gastroin

2019
Effects of sodium butyrate on intestinal health and gut microbiota composition during intestinal inflammation progression in broilers.
    Poultry science, 2019, Oct-01, Volume: 98, Issue:10

    Topics: Animal Feed; Animals; Anti-Inflammatory Agents; Butyric Acid; Chickens; Dextran Sulfate; Diet; Dieta

2019
Propionic Acid Induces Gliosis and Neuro-inflammation through Modulation of PTEN/AKT Pathway in Autism Spectrum Disorder.
    Scientific reports, 2019, 06-19, Volume: 9, Issue:1

    Topics: Autism Spectrum Disorder; Biomarkers, Tumor; Butyric Acid; Cell Differentiation; Cell Proliferation;

2019
Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Adipose Tissue; Amides; Animals; Butyric Acid; Diet, High-Fat; Disease Models, Animal; Enzyme Activa

2013
Sodium butyrate protects against severe burn-induced remote acute lung injury in rats.
    PloS one, 2013, Volume: 8, Issue:7

    Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage Fluid; Burns; Butyric Acid; Female; Granulocyte C

2013
Effects of Lactobacillus plantarum 2142 and sodium n-butyrate in lipopolysaccharide-triggered inflammation: comparison of a porcine intestinal epithelial cell line and primary hepatocyte monocultures with a porcine enterohepatic co-culture system.
    Journal of animal science, 2014, Volume: 92, Issue:9

    Topics: Animals; Butyric Acid; Cell Line; Coculture Techniques; Cytokines; Epithelial Cells; Gene Expression

2014
Sodium Butyrate Ameliorates L-Arginine-Induced Pancreatitis and Associated Fibrosis in Wistar Rat: Role of Inflammation and Nitrosative Stress.
    Journal of biochemical and molecular toxicology, 2015, Volume: 29, Issue:8

    Topics: Animals; Arginine; Butyric Acid; Down-Regulation; Fibrosis; Inflammation; Nitric Oxide Synthase Type

2015
Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway.
    Scientific reports, 2015, Aug-03, Volume: 5

    Topics: Adipocytes; Animals; Anti-Inflammatory Agents; Butyric Acid; Carrier Proteins; Disease Models, Anima

2015
Retinoic acid and sodium butyrate suppress the cardiac expression of hypertrophic markers and proinflammatory mediators in Npr1 gene-disrupted haplotype mice.
    Physiological genomics, 2016, 07-01, Volume: 48, Issue:7

    Topics: Animals; Biomarkers; Blood Pressure; Butyric Acid; Cytokines; Diastole; Haplotypes; Heart; Hypertrop

2016
Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells.
    PloS one, 2016, Volume: 11, Issue:7

    Topics: Apoptosis; Butyric Acid; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Epithelia

2016
Intestinal alkaline phosphatase and sodium butyrate may be beneficial in attenuating LPS-induced intestinal inflammation.
    Genetics and molecular research : GMR, 2016, Oct-17, Volume: 15, Issue:4

    Topics: Alkaline Phosphatase; Animals; Butyric Acid; Cattle; Gene Expression Regulation, Enzymologic; Inflam

2016
Normal human gingival fibroblasts undergo cytostasis and apoptosis after long-term exposure to butyric acid.
    Biochemical and biophysical research communications, 2017, Jan-22, Volume: 482, Issue:4

    Topics: Animals; Apoptosis; Butyric Acid; Caspase 8; Cell Division; Cell Survival; Cytokines; DNA Damage; Fi

2017
Comparison of three different application routes of butyrate to improve colonic anastomotic strength in rats.
    International journal of colorectal disease, 2017, Volume: 32, Issue:3

    Topics: Anastomosis, Surgical; Anastomotic Leak; Animals; Butyric Acid; Collagen; Colon; Drug Administration

2017
Sodium butyrate attenuates high-fat diet-induced steatohepatitis in mice by improving gut microbiota and gastrointestinal barrier.
    World journal of gastroenterology, 2017, Jan-07, Volume: 23, Issue:1

    Topics: Animals; Butyric Acid; Cytokines; Diet, High-Fat; Drug Evaluation, Preclinical; Dysbiosis; Gastroint

2017
Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins.
    Journal of medicinal chemistry, 2009, Oct-08, Volume: 52, Issue:19

    Topics: 3T3-L1 Cells; Animals; Butyric Acid; Crystallography, X-Ray; Drug Evaluation, Preclinical; Fatty Aci

2009
[Protective effects of sodium butyrate against lung injury in mice with endotoxemia].
    Sheng li xue bao : [Acta physiologica Sinica], 2012, Jun-25, Volume: 64, Issue:3

    Topics: Animals; Butyric Acid; Endotoxemia; Inflammation; Interleukin-6; Lipopolysaccharides; Lung; Lung Inj

2012