butyric acid has been researched along with Hemoglobinopathies in 5 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Hemoglobinopathies: A group of inherited disorders characterized by structural alterations within the hemoglobin molecule.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Butyric acid has been viewed with skepticism because of less convenient for long-term chronic therapy." | 6.40 | Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies. ( Pouillart, PR, 1998) |
| " The fact that valproic acid, a derivative of pentanoic acid, also induces gamma-globin expression suggests that short-chain fatty acid derivatives that are already approved for human use may possess the property of gamma-globin inducibility and may be of therapeutic relevance to the beta-chain hemoglobinopathies." | 3.69 | Stimulation of fetal hemoglobin production by short chain fatty acids. ( Blau, CA; Dover, G; Fournarakis, B; Josephson, B; Li, Q; Liakopoulou, E; Papayannopoulou, T; Raisys, V; Stamatoyannopoulos, G; Wolf, JA, 1995) |
| " However, application of these drugs at large is not yet justified because a series of questions concerning their long-term efficacy, the correct dosage and timing, their tolerance and toxicity, and the potential long-term dangers, including mutagenicity are still unresolved." | 2.40 | New therapies for the haemoglobinopathies. ( Loukopoulos, D, 1997) |
| "Butyric acid has been viewed with skepticism because of less convenient for long-term chronic therapy." | 2.40 | Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies. ( Pouillart, PR, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Brauer, M | 1 |
| al-Momen, AK | 1 |
| Faller, DV | 1 |
| Liakopoulou, E | 1 |
| Blau, CA | 1 |
| Li, Q | 1 |
| Josephson, B | 1 |
| Wolf, JA | 1 |
| Fournarakis, B | 1 |
| Raisys, V | 1 |
| Dover, G | 1 |
| Papayannopoulou, T | 1 |
| Stamatoyannopoulos, G | 1 |
| Loukopoulos, D | 1 |
| Pouillart, PR | 1 |
| Perrine, SP | 1 |
3 reviews available for butyric acid and Hemoglobinopathies
| Article | Year |
|---|---|
New therapies for the haemoglobinopathies.
Topics: Anemia, Sickle Cell; Antisickling Agents; Butyrates; Butyric Acid; Drug Therapy, Combination; Erythr | 1997 |
Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies.
Topics: Animals; Antineoplastic Agents; Butyric Acid; Colorectal Neoplasms; Hemoglobinopathies; Humans; Prod | 1998 |
Pharmacologic modulation of fetal globin gene expression in the perinatal period.
Topics: Animals; Butyrates; Butyric Acid; Dose-Response Relationship, Drug; Erythroblasts; Fetal Hemoglobin; | 1990 |
2 other studies available for butyric acid and Hemoglobinopathies
| Article | Year |
|---|---|
Butyrate treatment in beta-hemoglobinopathies.
Topics: Butyrates; Butyric Acid; Hemoglobinopathies; Humans | 1995 |
Stimulation of fetal hemoglobin production by short chain fatty acids.
Topics: Adult; Anemia, Sickle Cell; Animals; Anticonvulsants; Butyrates; Butyric Acid; Cells, Cultured; Epil | 1995 |