butyric acid has been researched along with Disease Models, Animal in 107 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (0.93) | 18.7374 |
| 1990's | 4 (3.74) | 18.2507 |
| 2000's | 2 (1.87) | 29.6817 |
| 2010's | 52 (48.60) | 24.3611 |
| 2020's | 48 (44.86) | 2.80 |
| Authors | Studies |
|---|---|
| Citraro, R; Constanti, A; De Caro, C; De Sarro, G; Leo, A; Mainardi, P; Marascio, N; Nesci, V; Russo, E; Striano, P; Tallarico, M | 1 |
| Bora, V; Goyal, RK; Johar, K; Patel, BM; Patel, D | 1 |
| Dash, D; Islam, R; Singh, R | 1 |
| Ai, Q; He, Y; Ji, YC; Li, LQ; She, X; Sun, Q; Wang, ZL | 1 |
| Chen, H; Chen, Q; Gong, Q; Li, G; Nie, H; Wang, C; Yang, F; Zhang, J; Zhang, Y; Zheng, B; Zheng, T | 1 |
| Abe, K; Fujitani, M; Inoue, R; Ishijima, T; Kishida, T; Liyanage, GSG; Okada, S; Shibutani, T | 1 |
| Hase, K; Katayama, Y; Kinashi, Y; Kishimura, A; Li, J; Matsui, T; Mori, T; Mu, Y; Tanaka, M; Yoshikawa, T | 1 |
| Dou, X; Feng, X; Gao, N; Li, Y; Li, Z; Ma, Z; Meng, L; Shan, A; Yan, D | 1 |
| Chen, MJ; Feng, Y; Gao, L; Lin, MX; Tong, ZQ; Wang, SD | 1 |
| Campolo, M; Casili, G; Cuzzocrea, S; Esposito, E; Filippone, A; Giuffrè, L; Lanza, M; Paterniti, I; Scuderi, SA | 1 |
| Aşan, M; Gur, S; Kaya-Sezginer, E; Kırlangıç, OF; Özen, FZ; Yilmaz, S; Yilmaz-Oral, D | 1 |
| Ding, ST; Jian, YX; Lei, YH; Liu, HD; Liu, MR; Miao, WT; Xu, JY; Xu, RC; Xu, WX; Yan, N | 1 |
| Balbo, I; Cristiano, C; Hoxha, E; Lippiello, P; Miniaci, MC; Russo, R; Tempia, F | 1 |
| Chen, S; Lin, H; Lin, Q; Luo, F; Luo, H; Peng, X; Wu, X; Xia, X; Yang, G; Ye, F; Zhang, Y; Zhu, L | 1 |
| Asatryan, L; Davies, DL; Gao, L | 1 |
| Bian, X; Li, L; Li, Y; Man, D; Shi, D; Wang, K; Wang, Q; Wang, S; Wu, J; Wu, W; Yang, L | 1 |
| Chen, Z; Dong, M; Feng, L; Guo, B; He, Y; Nong, Y; Pan, S; Qin, J; Qin, Y; Su, Z; Wang, Q; Wei, J; Zhong, X | 1 |
| Guo, TT; Jiang, L; Liu, HD; Ma, LJ; Sun, Y; Wang, FX; Zhang, Z; Zhu, RY | 1 |
| Ikeda, Y; Nagasaki, Y; Nishikawa, Y; Shashni, B; Tajika, Y | 1 |
| Bian, Z; Liao, W; Liu, H; Liu, L; Mao, L; Qin, Y; Sun, S; Sun, X; Yan, Y; Zha, L; Zhang, Q | 1 |
| Li, H; Li, Y; Liu, X; Tian, Z; Wang, R; Yu, Y | 1 |
| Ikeda, Y; Matsuda, S | 1 |
| De Oliveira, J; do Nascimento, ND; Fröhlich, NT; Gelain, DP; Gomes, HM; Kessler, F; Martins, A; Moreira, JCF; Paz, AH; Possa, L; Rodrigues, MS; Santos, L; Silveira, AK; Sirena, D | 1 |
| Ajadi, IO; Ajadi, MB; Areloegbe, SE; Aturamu, A; Bashir, AM; Eepho, OI; Fafure, AA; Olaniyi, KS; Oniyide, AA; Owolabi, OV | 1 |
| Gunduz, O; Karadag, CH; Tastekin, E; Topuz, RD | 1 |
| Du, Y; Tang, G; Yuan, W | 1 |
| Choi, SH; Jang, HC; Lee, YK; Lim, HL; Oh, HN; Oh, TJ; Park, KS; Sul, WJ | 1 |
| Alrafas, HR; Becker, W; Busbee, PB; Chatterjee, S; Dopkins, N; Menzel, L; Miranda, K; Nagarkatti, M; Nagarkatti, PS; Singh, U; Tang, C | 1 |
| Chen, J; Chen, Z; He, H; Huang, C; Li, Y; Liu, R; Ma, Y; Qiu, J; Tong, L; You, Q | 1 |
| Dal-Pont, GC; Gava, FF; Quevedo, J; Resende, WR; Tye, SJ; Valvassori, SS; Varela, RB | 1 |
| Baumann, A; Bergheim, I; Brandt, A; Burkard, M; Jin, CJ; Nier, A; Sellmann, C; Venturelli, S | 1 |
| Batsukh, A; Chimeddorj, B; Chuang, TH; Herr, DR; Huang, CM; Huang, YF; Traisaeng, S | 1 |
| Chang, EB; Chen, EB; Demsas, F; Eskandari, M; Ho, KJ; Jiang, Q; Layden, BT; Nooromid, M; Priyadarshini, M; Shapiro, K; Xiong, L | 1 |
| Bora, N; Bora, PS; Dasso, M; Lyzogubov, V | 1 |
| Han, D; Huang, S; Pang, J; Wang, J; Wang, S; Wu, Y; Wu, Z; Zhang, S | 1 |
| Gao, Y; Guo, Y; Li, X; Ya, B; Yin, H | 1 |
| Adeyanju, OA; Areola, DE; Badejogbin, OC; Dibia, C; Michael, OS; Olaniyi, KS; Olatunji, LA; Oniyide, AA; Soetan, OA; Soladoye, AO | 1 |
| Balasubramanian, N; Jadhav, M; Sagarkar, S; Sakharkar, AJ; Shahi, N; Sirmaur, R | 1 |
| Andrade, SP; Barcelos, LS; Bittencourt, LFF; Castro, PR; Larochelle, S; Mackay, CR; Moulin, VJ; Slevin, M | 1 |
| Chen, W; Kong, Q; Li, X; Tian, P; Wang, B; Wang, G; Zhang, H; Zhao, J | 1 |
| Qin, B; Qu, Y; Zhang, N | 1 |
| Makizaki, Y; Ohno, H; Tanaka, Y; Uemoto, T; Yamamoto, M; Yokota, H | 1 |
| Jiang, Y; Li, K; Li, X; Xu, L; Yang, Z | 1 |
| Limoee, M; Mohammadi-Farani, A; Shirooie, S | 1 |
| Bai, J; Cai, G; Cui, A; Dai, X; Fan, JG; Han, Y; Hu, Z; Li, Y; Liu, XL; Liu, Y; Liu, Z; Ma, F; Pan, Q; Ren, TY; Shen, F; Su, W; Wang, ZX; Xin, FZ; Xue, Y; Zhang, F; Zhao, ZH; Zhou, D | 1 |
| Han, SS; Hou, J; Li, CX; Liu, FY; Pang, WL; Sun, CB; Wang, C; Wen, J; Xing, HJ; Yan, JY; Yang, ZS; Yin, W; Ying, Y; Yuan, JL; Zhang, SQ; Zhou, LC | 1 |
| Beisner, J; Bischoff, SC; Filipe Rosa, L; Günther, C; Kaden-Volynets, V; Stolzer, I | 1 |
| Dubey, SK; K C, S; Kakoty, V; Taliyan, R; Yang, CH | 1 |
| Abdulla, OA; Alghetaa, HK; Busbee, PB; Nagarkatti, M; Nagarkatti, P; Neamah, W; Singh, N; Sultan, M | 1 |
| Patel, BM | 1 |
| Chen, X; Liang, D; Liu, G; Olsen, N; Su, W; Tang, F; Wan, T; Yu, J; Zheng, SG; Zhu, W | 1 |
| Andersen, AD; Cilieborg, MS; Lauridsen, C; Mørkbak, AL; Sangild, PT | 1 |
| Fu, YH; Wang, JJ; Wang, YN; Wei, ZK; Yang, ZT; Zhang, X | 1 |
| Chen, DZ; Chen, L; Chen, YP; Gong, YW; Hu, ED; Huang, Y; Jin, XY; Li, H; Lin, Z; Lu, FB; Wang, XD; Wu, JL; Xu, LM; Zhao, MF; Zheng, MH; Zou, JY | 1 |
| Li, LX; Li, M; Li, YQ; Long, X; Sun, YY; Zhang, WX; Zhao, DY | 1 |
| Aizawa, H; Akagi, H; Asano, S; Harada, K; Ito, H; Kanematsu, T; Nozaki, K; Oda, K; Shirawachi, S; Yamawaki, S; Yamawaki, Y; Yoshioka, N | 1 |
| Chen, DZ; Chen, L; Chen, YP; Gong, YW; Hu, ED; Huang, Y; Jin, XY; Li, H; Li, J; Lin, Z; Lu, FB; Wang, XD; Wu, JL; Xu, LM; Zheng, MH | 1 |
| Cho, KK; Choi, IS; Kim, IS; Kim, JA; Kim, SC; Kim, SH; Lee, SH; Lee, SS; Yu, DY; Yun, CH | 1 |
| Carl, D; Gehr, TWB; Ghosh, S; Ghosh, SS; Gonzalez, A; Krieg, R; Massey, HD | 1 |
| Bellettini-Santos, T; Budni, J; Campos, ACBF; da Silva, S; Damiani, AP; de Andrade, VM; de Carvalho, CA; Garcez, ML; Longaretti, LM; Mina, F; Schiavo, GL; Valvassori, SS; Varela, RB | 1 |
| Chen, YW; Fan, JG; Liu, XL; Pan, Q; Xin, FZ; Yang, RX; Zhao, ZH; Zhou, D; Zhou, H | 1 |
| Jaworska, J; Sypecka, J; Zalewska, T; Ziemka-Nalecz, M | 1 |
| Abete, P; Aitoro, R; Avagliano, C; Berni Canani, R; Bianco, R; Bonaduce, D; Calignano, A; Ciccarelli, M; Fiordelisi, A; Ghigo, A; Guida, F; Hirsch, E; Iaccarino, G; Li, M; Mercurio, V; Napolitano, F; Paparo, L; Russo, M; Sala, V; Sorriento, D; Tocchetti, CG; Trinchese, G | 1 |
| Hu, S; Li, H; Li, X; Tian, S; Wang, Z; Wu, B; Wu, J; Yang, H; Zhou, Z | 1 |
| Cuadrado-Tejedor, M; Franco, R; Garcia-Osta, A; Ricobaraza, AL; Torrijo, R | 1 |
| Ahmad, ST; O'Brien, LM; St Laurent, R | 1 |
| Amano, Y; Ansary, MM; Harashima, N; Ishihara, S; Itoh, K; Kinoshita, Y; Kusunoki, R; Mishiro, T; Otani, A; Sato, S; Tongu, M; Yamada, T | 1 |
| Calignano, A; Canani, RB; Ferrante, MC; Iacono, A; Mattace Raso, G; Meli, R; Paciello, O; Russo, R; Santoro, A; Simeoli, R | 1 |
| Andersen, ML; Arent, CO; Bavaresco, DV; Quevedo, J; Resende, WR; Réus, GZ; Ribeiro, KF; Valvassori, SS; Varela, RB; Zugno, AI | 1 |
| de Theije, CG; Garssen, J; Knol, J; Kraneveld, AD; Lambert, J; Oozeer, R; Ramadan, M; van Eijndthoven, T; Wopereis, H | 1 |
| Choi, YR; Jang, SK; Joo, SS; Kim, HB; Kim, HJ; Kim, SM; Kim, ST; Lee, DI; Lee, KH; Seo, DW; Yu, JM | 1 |
| Jena, GB; Khan, S | 1 |
| Bernalier-Donadille, A; Chassard, C; Del'homme, C; Dostal, A; Lacroix, C; Pham, VT; Zimmermann, MB | 1 |
| Ahn, YM; Kim, SH; Kim, YS; Park, HG; Park, S; Yu, HS | 1 |
| Chung, SY; Han, A; Kwon, MS; Sung, YB | 1 |
| Gong, ZJ; Han, XQ; Li, X; Wang, LK; Wang, LW; Yang, F | 1 |
| Chang, YM; Chen, YL; Chou, AH; Hu, SH; Wang, HL | 1 |
| Abdolghaffari, AH; Abdollahi, M; Baeeri, M; Ghasemi-Niri, SF; Moeinian, M; Mozaffari, S; Navaea-Nigjeh, M | 1 |
| Arent, CO; Bobsin, TS; Budni, J; Dal-Pont, GC; Quevedo, J; Reus, GZ; Valvassori, SS; Varela, RB | 1 |
| Ago, Y; Hara, Y; Hashimoto, H; Hayata-Takano, A; Kataoka, S; Kawanai, T; Maeda, Y; Matsuda, T; Takano, E; Takuma, K; Watanabe, R | 1 |
| Chen, MJ; Gong, Q; Li, G; Nie, H; Shu, KG; Wang, C; Zhang, YX | 1 |
| Gonçalves, CL; Lopes-Borges, J; Quevedo, J; Streck, EL; Tonin, PT; Valvassori, SS; Varela, RB; Vieira, JS | 1 |
| Amboni, RT; Bianchini, G; Dal-Pont, GC; Lopes-Borges, J; Mariot, E; Quevedo, J; Valvassori, SS; Varela, RB | 1 |
| Lavebratt, C; Mathé, AA; Melas, PA; Wegener, G; Wei, Y | 1 |
| Malago, JJ; Sangu, CL | 1 |
| Albuquerque, P; Brandão, FA; Derengowski, LS; Nicola, AM; Poças-Fonseca, MJ; Silva-Pereira, I | 1 |
| Bavaresco, DV; Budni, J; Carvalho, AF; Dal-Pont, GC; Furlanetto, CB; Gonçalves, CL; Quevedo, J; Resende, WR; Réus, GZ; Streck, EL; Valvassori, SS | 1 |
| He, G; Peng, Y; Wang, X; Wang, Y; Zhang, B; Zhong, W | 1 |
| Bucki, R; Byfield, FJ; Janmey, PA; Niemirowicz, K; Piktel, E; Savage, PB; Wątek, M; Wnorowska, U | 1 |
| Elliott, E; Getselter, D; Kratsman, N | 1 |
| Arent, CO; Carvalho, AF; Dal-Pont, GC; Lopes-Borges, J; Mariot, E; Quevedo, J; Resende, WR; Steckert, AV; Valvassori, SS; Varela, RB | 1 |
| Gean, PW; Hsiao, YH; Su, CL; Su, CW | 1 |
| Beland, FA; de Conti, A; Fernandes, LH; Furtado, KS; Heidor, R; Horst, MA; Moreno, FS; Ortega, JF; Pogribna, M; Pogribny, IP; Shpyleva, S; Tavares, PE; Tryndyak, V | 1 |
| de Farias, CB; Dornelles, AS; Lichtenfels, M; Parent, MB; Petry, FS; Roesler, R; Schwartsmann, G; Valiati, FE | 1 |
| Long, W; Pang, X; Wang, J; Wang, L; Wu, G; Wu, Y; Xue, Z; Zhang, C; Zhang, Q; Zhang, X; Zhao, L; Zhao, Y | 1 |
| Heidor, R; Moreno, FS; Pogribny, IP | 1 |
| Albuquerque Filho, MO; Crivelaro, PC; de Freitas, BS; de Lima, MN; Garcia, RC; Schröder, N | 1 |
| Dewulf, J; Ducatelle, R; Haesebrouck, F; Lanckriet, A; Nollet, N; Schwarzer, K; Timbermont, L; Van Immerseel, F | 1 |
| Bianchi, F; Cantoni, S; Cappuccilli, M; Cenacchi, G; Claudia, C; Della Bella, E; La Manna, G; Nardo, B; Neri, F; Pasquinelli, G; Stefoni, S; Tarantino, L; Tsivian, M; Valente, S; Ventura, C | 1 |
| Benedet, J; Ferreira, CL; Kapczinski, F; Moretti, M; Quevedo, J; Rochi, N; Scaini, G; Streck, EL; Valvassori, SS; Varela, RB; Zugno, AI | 1 |
| Ariake, K; Eishi, Y; Hoshi, S; Kumagai, J; Ohkusa, T; Sakurazawa, T; Yajima, T | 1 |
| Babyatsky, MW; Chauvin, SN; Holzman, IR; Lin, J; Magid, MS; Nafday, SM; Pabbatireddy, S | 1 |
| Le Leu, RK; McIntosh, GH; Royle, PJ; Young, GP | 1 |
| Horiuchi, M; Inoue, F; Kinugasa, A; Kizaki, Z; Kodo, N; Nakajima, T; Saheki, T; Sawada, T; Yamanaka, H | 1 |
| Bensaada, M; Butel, MJ; Favre, A; Hibert, A; Popot, F; Rimbault, A; Roland, N; Szylit, O; Tessedre, AC | 1 |
| Agricola, B; Byrne, E; Donahue, RE; Dover, GJ; McDonagh, KT; Nathan, DG; Nienhuis, AW | 1 |
| Dvorak, AM; Galli, SJ; Hammel, I | 1 |
1 review(s) available for butyric acid and Disease Models, Animal
| Article | Year |
|---|---|
Nutritional Epigenetics and the Prevention of Hepatocellular Carcinoma with Bioactive Food Constituents.
Topics: Animals; Butyric Acid; Carcinoma, Hepatocellular; Catechin; Cell Line, Tumor; Curcumin; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Food; Humans; Isothiocyanates; Phytochemicals; Resveratrol; Stilbenes; Sulfoxides | 2016 |
106 other study(ies) available for butyric acid and Disease Models, Animal
| Article | Year |
|---|---|
Increased efficacy of combining prebiotic and postbiotic in mouse models relevant to autism and depression.
Topics: Animals; Anxiety; Autistic Disorder; Avoidance Learning; Behavior, Animal; Brain-Gut Axis; Butyric Acid; Depression; Disease Models, Animal; Drug Synergism; Gastrointestinal Microbiome; Humans; Lactalbumin; Male; Memory; Mice; Mice, Inbred C57BL; Prebiotics; Social Behavior; Stress, Psychological; Swimming | 2021 |
Systemic study of selected histone deacetylase inhibitors in cardiac complications associated with cancer cachexia.
Topics: Animals; Benzamides; Butyric Acid; Cachexia; Cell Line, Tumor; Disease Models, Animal; Disease Progression; Female; Heart Diseases; Histone Deacetylase Inhibitors; Hydroxamic Acids; Male; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasms; Pyridines; Pyrroles | 2022 |
Intranasal curcumin and sodium butyrate modulates airway inflammation and fibrosis via HDAC inhibition in allergic asthma.
Topics: Administration, Intranasal; Animals; Anti-Inflammatory Agents; Asthma; Bronchoalveolar Lavage Fluid; Butyric Acid; Curcumin; Disease Models, Animal; Fibrosis; Histone Deacetylase Inhibitors; Immunoglobulin E; Inflammation; Lung; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Ovalbumin | 2022 |
Sodium Butyrate Alleviates Intestinal Inflammation in Mice with Necrotizing Enterocolitis.
Topics: Animals; Butyric Acid; Disease Models, Animal; Enterocolitis, Necrotizing; Female; HMGB1 Protein; Intestines; Male; Mice; Mice, Inbred C57BL; NF-kappa B; Random Allocation; Toll-Like Receptor 4 | 2021 |
Sodium butyrate ameliorates Schistosoma japonicum-induced liver fibrosis by inhibiting HMGB1 expression.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Blotting, Western; Butyric Acid; Cytokines; Disease Models, Animal; Down-Regulation; Enzyme-Linked Immunosorbent Assay; Female; Histamine Antagonists; HMGB1 Protein; Humans; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Neglected Diseases; Real-Time Polymerase Chain Reaction; Schistosoma japonicum; Schistosomiasis japonica; Specific Pathogen-Free Organisms; Zoonoses | 2021 |
Effects of Soy Isoflavones, Resistant Starch and Antibiotics on Polycystic Ovary Syndrome (PCOS)-Like Features in Letrozole-Treated Rats.
Topics: Animals; Anti-Bacterial Agents; Biomarkers; Butyric Acid; Disease Models, Animal; Equol; Female; Gastrointestinal Microbiome; Isoflavones; Letrozole; Polycystic Ovary Syndrome; Rats; Resistant Starch; Severity of Illness Index; Soy Foods | 2021 |
Polyvinyl Butyrate Nanoparticles as Butyrate Donors for Colitis Treatment.
Topics: Animals; Biocompatible Materials; Butyric Acid; Cells, Cultured; Colitis; Dextran Sulfate; Disease Models, Animal; Drug Carriers; Male; Materials Testing; Mice; Mice, Inbred C57BL; Molecular Structure; Nanoparticles; Particle Size; Polyvinyls; RAW 264.7 Cells | 2021 |
Sodium butyrate alleviates intestinal injury and microbial flora disturbance induced by lipopolysaccharides in rats.
Topics: Animals; Anti-Inflammatory Agents; Butyric Acid; Dietary Supplements; Disease Models, Animal; Gastrointestinal Microbiome; Intestinal Diseases; Lipopolysaccharides; Male; Rats; Rats, Sprague-Dawley | 2022 |
Composite Sophora Colon-Soluble Capsule Ameliorates DSS-Induced Ulcerative Colitis in Mice via Gut Microbiota-Derived Butyric Acid and NCR
Topics: Animals; Butyric Acid; Colitis; Colitis, Ulcerative; Colon; Disease Models, Animal; Gastrointestinal Microbiome; Immunity, Innate; Lymphocytes; Male; Mice; Mice, Inbred C57BL; Sophora | 2023 |
Supplementation with SCFAs Re-Establishes Microbiota Composition and Attenuates Hyperalgesia and Pain in a Mouse Model of NTG-Induced Migraine.
Topics: Animals; Butyric Acid; Dietary Supplements; Disease Models, Animal; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Hyperalgesia; Mice; Migraine Disorders; Nitroglycerin; Pain | 2022 |
Sodium butyrate ameliorates erectile dysfunction through fibrosis in a rat model of partial bladder outlet obstruction.
Topics: Animals; Butyric Acid; Disease Models, Animal; Erectile Dysfunction; Fibrosis; Histone Deacetylases; Humans; Inflammation; Male; NF-E2-Related Factor 2; NF-kappa B; Nitric Oxide Synthase Type III; Penis; Phenylephrine; Prostatic Hyperplasia; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta1; Transforming Growth Factors; Tumor Necrosis Factor-alpha; Urinary Bladder Neck Obstruction | 2022 |
Neuroprotective Effects of Sodium Butyrate and Monomethyl Fumarate Treatment through GPR109A Modulation and Intestinal Barrier Restoration on PD Mice.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Animals; Butyric Acid; Claudin-1; Cytokines; Disease Models, Animal; Dopamine; Fumarates; Ligands; Male; Mice; Mice, Inbred C57BL; Neuroprotective Agents; NF-kappa B; Occludin; Parkinson Disease; Receptors, G-Protein-Coupled; Serotonin; Tyrosine 3-Monooxygenase | 2022 |
Maternal treatment with sodium butyrate reduces the development of autism-like traits in mice offspring.
Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Behavior, Animal; Butyric Acid; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Social Behavior | 2022 |
Oryzanol Ameliorates DSS-Stimulated Gut Barrier Damage via Targeting the Gut Microbiota Accompanied by the TLR4/NF-κB/NLRP3 Cascade Response In Vivo.
Topics: Animals; Butyric Acid; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Inflammatory Bowel Diseases; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Rats; Toll-Like Receptor 4 | 2022 |
Sodium Butyrate Supplementation Modulates Neuroinflammatory Response Aggravated by Antibiotic Treatment in a Mouse Model of Binge-like Ethanol Drinking.
Topics: Alcohol Drinking; Alcoholism; Animals; Anti-Bacterial Agents; Butyric Acid; Cytokines; Dietary Supplements; Disease Models, Animal; Ethanol; Inflammation; Mice; Mice, Inbred C57BL | 2022 |
Intermittent Fasting Alleviates Risk Markers in a Murine Model of Ulcerative Colitis by Modulating the Gut Microbiome and Metabolome.
Topics: Akkermansia; Animals; Bile Acids and Salts; Butyric Acid; Chromatography, Liquid; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Gastrointestinal Microbiome; Interleukin-6; Intermittent Fasting; Male; Metabolome; Mice; Mice, Inbred C57BL; Tandem Mass Spectrometry | 2022 |
Preventive effect of tilapia skin collagen hydrolysates on ulcerative colitis mice based on metabonomic and 16 S rRNA gene sequencing.
Topics: Acetic Acid; Actinobacteria; Animals; Bacteroidetes; Butyric Acid; Colitis; Colitis, Ulcerative; Collagen; Colon; Dextran Sulfate; Disease Models, Animal; Firmicutes; Genes, rRNA; Mice; Mice, Inbred C57BL; Tilapia | 2023 |
Neuroprotective Effects of Sodium Butyrate by Restoring Gut Microbiota and Inhibiting TLR4 Signaling in Mice with MPTP-Induced Parkinson's Disease.
Topics: Animals; Butyric Acid; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Neuroprotective Agents; Parkinson Disease; RNA, Ribosomal, 16S; Toll-Like Receptor 4 | 2023 |
Self-assembling polymer-based short chain fatty acid prodrugs ameliorate non-alcoholic steatohepatitis and liver fibrosis.
Topics: Animals; Butyric Acid; Disease Models, Animal; Fatty Acids, Volatile; Liver; Liver Cirrhosis; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease; Polymers; Prodrugs | 2023 |
Sodium Butyrate Inhibits Oxidative Stress and NF-κB/NLRP3 Activation in Dextran Sulfate Sodium Salt-Induced Colitis in Mice with Involvement of the Nrf2 Signaling Pathway and Mitophagy.
Topics: Animals; Butyric Acid; Colitis; Colitis, Ulcerative; Cyclooxygenase 2; Dextran Sulfate; Disease Models, Animal; Mice; Mice, Inbred C57BL; Mitophagy; NF-E2-Related Factor 2; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Oxidative Stress; Reactive Oxygen Species; Signal Transduction; Sodium Chloride | 2023 |
Protective effect of sodium butyrate on intestinal barrier damage and uric acid reduction in hyperuricemia mice.
Topics: Animals; Butyric Acid; Caco-2 Cells; Disease Models, Animal; Fatty Acids, Volatile; Humans; Hyperuricemia; Mice; Mice, Inbred C57BL; Occludin; Uric Acid | 2023 |
Gut Protective Effect from D-Methionine or Butyric Acid against DSS and Carrageenan-Induced Ulcerative Colitis.
Topics: Animals; Butyric Acid; Carrageenan; Colitis; Colitis, Ulcerative; Dextran Sulfate; Disease Models, Animal; Inflammation; Inflammatory Bowel Diseases; Methionine; Mice; Mice, Inbred C57BL; Racemethionine | 2023 |
Sodium Butyrate Protects Against Intestinal Oxidative Damage and Neuroinflammation in the Prefrontal Cortex of Ulcerative Colitis Mice Model.
Topics: Animals; Butyric Acid; Claudin-5; Colitis, Ulcerative; Disease Models, Animal; Inflammation; Inflammatory Bowel Diseases; Mice; Neuroinflammatory Diseases; NF-E2-Related Factor 2; Occludin; Prefrontal Cortex | 2023 |
Modulation of GABA by sodium butyrate ameliorates hypothalamic inflammation in experimental model of PCOS.
Topics: Animals; Butyric Acid; Disease Models, Animal; Female; gamma-Aminobutyric Acid; Humans; Letrozole; Models, Theoretical; Polycystic Ovary Syndrome; Rats; Rats, Wistar | 2023 |
Effects of hippocampal histone acetylation and HDAC inhibition on spatial learning and memory in the Morris water maze in rats.
Topics: Acetylation; Animals; Butyric Acid; Disease Models, Animal; Hippocampus; Histone Deacetylase Inhibitors; Histones; Male; Maze Learning; Memory; Memory Disorders; Rats; Rats, Sprague-Dawley; Scopolamine; Spatial Learning | 2020 |
Suppression of HDAC2 by sodium butyrate alleviates apoptosis of kidney cells in db/db mice and HG‑induced NRK‑52E cells.
Topics: Animals; Apoptosis; Butyric Acid; Cell Line; Diabetic Nephropathies; Disease Models, Animal; Gene Expression Regulation; Histone Deacetylase 2; Kidney; Male; Mice; Models, Biological; Oxidative Stress; Reactive Oxygen Species | 2020 |
Butyrate attenuated fat gain through gut microbiota modulation in db/db mice following dapagliflozin treatment.
Topics: Adipose Tissue; Animals; Benzhydryl Compounds; Butyric Acid; Disease Models, Animal; Gastrointestinal Microbiome; Glucose; Glucosides; Liver; Mice; Obesity; Sodium-Glucose Transporter 2 Inhibitors; Weight Gain | 2019 |
Indole-3-carbinol prevents colitis and associated microbial dysbiosis in an IL-22-dependent manner.
Topics: Animals; Butyric Acid; Colitis; Colon; Disease Models, Animal; Dysbiosis; Female; Gastrointestinal Microbiome; Indoles; Inflammation; Interleukin-22; Interleukins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; RNA, Ribosomal, 16S; Th17 Cells | 2020 |
Lipopolysaccharide-Induced Depression-Like Behaviors Is Ameliorated by Sodium Butyrate via Inhibiting Neuroinflammation and Oxido-Nitrosative Stress.
Topics: Animals; Antidepressive Agents; Behavior, Animal; Butyric Acid; Cytokines; Depression; Disease Models, Animal; Hindlimb Suspension; Hippocampus; Inflammation; Lipopolysaccharides; Male; Mice; Mice, Inbred C57BL; Nitrosative Stress; Oxidative Stress; Physical Conditioning, Animal; Prefrontal Cortex; Swimming | 2020 |
HDAC inhibitors reverse mania-like behavior and modulate epigenetic regulatory enzymes in an animal model of mania induced by Ouabain.
Topics: Animals; Behavior, Animal; Bipolar Disorder; Butyric Acid; Corpus Striatum; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; Frontal Lobe; Hippocampus; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Locomotion; Male; Mania; Ouabain; Rats; Rats, Wistar; Signal Transduction; Treatment Outcome; Valproic Acid | 2020 |
Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis.
Topics: Animals; Butyric Acid; Cholesterol, Dietary; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Disease Progression; Female; Glucose; Inflammation; Interleukin-6; Intestine, Small; Liver; Melatonin; Mice, Inbred C57BL; Nitric Oxide Synthase Type II; Non-alcoholic Fatty Liver Disease; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2020 |
Leuconostoc mesenteroides fermentation produces butyric acid and mediates Ffar2 to regulate blood glucose and insulin in type 1 diabetic mice.
Topics: Animals; Blood Glucose; Butyric Acid; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Fermentation; Food Microbiology; Gastrointestinal Microbiome; Insulin; Leuconostoc mesenteroides; Mice; Probiotics; Receptors, G-Protein-Coupled | 2020 |
Microbe-Derived Butyrate and Its Receptor, Free Fatty Acid Receptor 3, But Not Free Fatty Acid Receptor 2, Mitigate Neointimal Hyperplasia Susceptibility After Arterial Injury.
Topics: Animals; Anti-Bacterial Agents; Bacteria; Butyric Acid; Cell Movement; Cell Proliferation; Disease Models, Animal; Femoral Artery; Gastrointestinal Microbiome; Hyperplasia; Mice, Inbred C57BL; Mice, Knockout; Neointima; Receptors, G-Protein-Coupled; Signal Transduction; Vancomycin; Vascular System Injuries | 2020 |
Role of thalidomide, senicapoc, and sodium butyrate in choroidal neovascularization.
Topics: Acetamides; Angiogenesis Inhibitors; Animals; Butyric Acid; Cell Line; Cell Proliferation; Choroidal Neovascularization; Disease Models, Animal; Human Umbilical Vein Endothelial Cells; Humans; Male; Mice, Inbred C57BL; Thalidomide; Trityl Compounds | 2020 |
Resistant Maltodextrin Alleviates Dextran Sulfate Sodium-Induced Intestinal Inflammatory Injury by Increasing Butyric Acid to Inhibit Proinflammatory Cytokine Levels.
Topics: Animals; Butyric Acid; Colitis; Colon; Cytokines; Dextran Sulfate; Disease Models, Animal; Feces; Female; Inflammation; Inflammation Mediators; Intestinal Mucosa; Lactic Acid; Mice, Inbred C57BL; Polysaccharides | 2020 |
Myricitrin ameliorates cognitive deficits in MCAO cerebral stroke rats via histone acetylation-induced alterations of brain-derived neurotrophic factor.
Topics: Acetylation; Animals; Brain-Derived Neurotrophic Factor; Butyric Acid; Cerebral Cortex; Cognitive Dysfunction; Disease Models, Animal; Flavonoids; Histamine Antagonists; Histone Deacetylases; Histones; Infarction, Middle Cerebral Artery; Rats; Rats, Sprague-Dawley; Spatial Memory; Stroke | 2021 |
Sodium butyrate arrests pancreato-hepatic synchronous uric acid and lipid dysmetabolism in high fat diet fed Wistar rats.
Topics: Animals; Blood Glucose; Butyric Acid; Diet, High-Fat; Disease Models, Animal; Dyslipidemias; Female; Glucose Metabolism Disorders; Hyperuricemia; Hypoglycemic Agents; Hypolipidemic Agents; Lipids; Liver; Metabolic Syndrome; Pancreas; Rats, Wistar; Uric Acid | 2021 |
Role for Histone Deacetylation in Traumatic Brain Injury-Induced Deficits in Neuropeptide Y in Arcuate Nucleus: Possible Implications in Feeding Behavior.
Topics: Animals; Arcuate Nucleus of Hypothalamus; Behavior, Animal; Brain Concussion; Butyric Acid; Disease Models, Animal; Feeding Behavior; Histone Deacetylase Inhibitors; Neuropeptide Y; Rats | 2021 |
GPR43 regulates sodium butyrate-induced angiogenesis and matrix remodeling.
Topics: Angiogenesis Inducing Agents; Animals; Butyric Acid; Cell Line; Cell Movement; Cell Proliferation; Collagen; Disease Models, Animal; Extracellular Matrix; Fibroblasts; Granulation Tissue; Humans; Male; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Physiologic; Receptors, G-Protein-Coupled; Surgical Sponges; Transforming Growth Factor beta1 | 2021 |
Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and sexual maturation.
Topics: Animals; Autistic Disorder; Behavior, Animal; Butyric Acid; Disease Models, Animal; Fatty Acids, Volatile; Gastrointestinal Microbiome; Lactobacillus; Probiotics; Rats; Serotonin; Sexual Maturation; Tryptophan; Valproic Acid; Weaning | 2021 |
Sodium butyrate ameliorates non-alcoholic fatty liver disease by upregulating miR-150 to suppress CXCR4 expression.
Topics: Alanine Transaminase; Animals; Butyric Acid; Diet, High-Fat; Disease Models, Animal; Non-alcoholic Fatty Liver Disease; Triglycerides; Tumor Necrosis Factor-alpha | 2021 |
Improvement of loperamide-induced slow transit constipation by Bifidobacterium bifidum G9-1 is mediated by the correction of butyrate production and neurotransmitter profile due to improvement in dysbiosis.
Topics: Animals; Bifidobacterium bifidum; Butyrates; Butyric Acid; Constipation; Disease Models, Animal; Dopamine; Dysbiosis; Feces; Gastrointestinal Microbiome; Gastrointestinal Motility; Gene Expression Regulation, Enzymologic; Humans; Laxatives; Loperamide; Neurotransmitter Agents; Probiotics; Quality of Life; Rats; Serotonin; Tryptophan Hydroxylase | 2021 |
Sodium butyrate ameliorates the impairment of synaptic plasticity by inhibiting the neuroinflammation in 5XFAD mice.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Brain; Butyric Acid; Cognitive Dysfunction; Disease Models, Animal; Disks Large Homolog 4 Protein; Inflammation; Long-Term Potentiation; Mice, Transgenic; Microglia; Morris Water Maze Test; Neuronal Plasticity; Synaptophysin | 2021 |
Sodium butyrate enhances fear extinction and rescues hippocampal acetylcholinesterase activity in a rat model of posttraumatic stress disorder.
Topics: Acetylcholine; Acetylcholinesterase; Animals; Butyric Acid; Cholinergic Neurons; Disease Models, Animal; Extinction, Psychological; Fear; Hippocampus; Histone Deacetylase Inhibitors; Histone Deacetylases; Rats; Stress Disorders, Post-Traumatic; Synaptic Transmission; Treatment Outcome | 2021 |
Sodium Butyrate Supplementation Inhibits Hepatic Steatosis by Stimulating Liver Kinase B1 and Insulin-Induced Gene.
Topics: AMP-Activated Protein Kinases; Animals; Butyric Acid; Diet, High-Fat; Dietary Supplements; Disease Models, Animal; Gene Expression Regulation; Hepatocytes; Humans; Insulin; Lipid Metabolism; Lipogenesis; Male; MAP Kinase Signaling System; Mice; Models, Biological; Non-alcoholic Fatty Liver Disease; Phosphorylation | 2021 |
Gastrodia remodels intestinal microflora to suppress inflammation in mice with early atherosclerosis.
Topics: Acetic Acid; Animals; Aorta; Atherosclerosis; Benzyl Alcohols; Butyric Acid; Disease Models, Animal; Drugs, Chinese Herbal; Fatty Acids, Volatile; Gastrodia; Gastrointestinal Microbiome; Glucosides; Inflammation; Intercellular Adhesion Molecule-1; Interleukin-1beta; Intestinal Mucosa; Lipids; Mice, Inbred C57BL; Propionates; Tight Junction Proteins; Tumor Necrosis Factor-alpha | 2021 |
Prebiotic Inulin and Sodium Butyrate Attenuate Obesity-Induced Intestinal Barrier Dysfunction by Induction of Antimicrobial Peptides.
Topics: Animal Feed; Animals; Biomarkers; Butyric Acid; Dietary Supplements; Disease Models, Animal; Female; Gastrointestinal Microbiome; Intestinal Mucosa; Inulin; Liver; Mice; Obesity; Permeability; Pore Forming Cytotoxic Proteins; Prebiotics; Tight Junctions | 2021 |
Neuroprotective Effects of Trehalose and Sodium Butyrate on Preformed Fibrillar Form of α-Synuclein-Induced Rat Model of Parkinson's Disease.
Topics: alpha-Synuclein; Animals; Butyric Acid; Disease Models, Animal; Neuroprotective Agents; Parkinson Disease; Rats; Rats, Wistar; Trehalose | 2021 |
The Ability of AhR Ligands to Attenuate Delayed Type Hypersensitivity Reaction Is Associated With Alterations in the Gut Microbiota.
Topics: Animals; Basic Helix-Loop-Helix Transcription Factors; Butyric Acid; Carbazoles; Cytokines; Disease Models, Animal; Female; Gastrointestinal Microbiome; Hypersensitivity, Delayed; Ligands; Mice; Mice, Inbred C57BL; Polychlorinated Dibenzodioxins; Receptors, Aryl Hydrocarbon; T-Lymphocytes, Regulatory; Th17 Cells | 2021 |
Sodium Butyrate Controls Cardiac Hypertrophy in Experimental Models of Rats.
Topics: Animals; Aorta, Abdominal; Butyric Acid; Collagen; Constriction; Disease Models, Animal; DNA, Mitochondrial; Female; Heart Ventricles; Histone Deacetylase 2; Histone Deacetylase Inhibitors; Hypertrophy, Left Ventricular; Male; Oxidative Stress; Rats, Wistar; Ventricular Function, Left; Ventricular Remodeling | 2018 |
Sodium butyrate regulates Th17/Treg cell balance to ameliorate uveitis via the Nrf2/HO-1 pathway.
Topics: Animals; Butyric Acid; Disease Models, Animal; Female; Flow Cytometry; Heme Oxygenase-1; Membrane Proteins; Mice, Inbred C57BL; NF-E2-Related Factor 2; T-Lymphocytes, Regulatory; Th17 Cells; Uveitis | 2017 |
Supplementation with Lactobacillus paracasei or Pediococcus pentosaceus does not prevent diarrhoea in neonatal pigs infected with Escherichia coli F18.
Topics: Acetic Acid; Animals; Animals, Newborn; Butyric Acid; Colon; Colony Count, Microbial; Diarrhea; Diet; Dietary Supplements; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Intestinal Mucosa; Intestines; Lacticaseibacillus paracasei; Pediococcus pentosaceus; Probiotics; Sus scrofa; Swine; Swine Diseases | 2017 |
Butyrate protects against disruption of the blood-milk barrier and moderates inflammatory responses in a model of mastitis induced by lipopolysaccharide.
Topics: Animals; Butyric Acid; Disease Models, Animal; Epithelial Cells; Female; Inflammation; Lipopolysaccharides; Mastitis; Mice; Mice, Inbred BALB C; Milk; NF-kappa B; Signal Transduction | 2017 |
Sodium butyrate ameliorates S100/FCA-induced autoimmune hepatitis through regulation of intestinal tight junction and toll-like receptor 4 signaling pathway.
Topics: Animals; Butyric Acid; Cells, Cultured; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Freund's Adjuvant; Hepatitis, Animal; Hepatitis, Autoimmune; Humans; Interleukin-6; Intestine, Small; Liver; Male; Mice; Mice, Inbred C57BL; S100 Proteins; Signal Transduction; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2017 |
Butyrate promotes visceral hypersensitivity in an IBS-like model via enteric glial cell-derived nerve growth factor.
Topics: Animals; Butyric Acid; Cell Line; Disease Models, Animal; Enteric Nervous System; Gene Expression Profiling; Histone Deacetylase Inhibitors; Hydroxamic Acids; Irritable Bowel Syndrome; Male; Nerve Growth Factor; Neuroglia; Rats, Sprague-Dawley; Transcriptome; Visceral Pain | 2018 |
Sodium butyrate abolishes lipopolysaccharide-induced depression-like behaviors and hippocampal microglial activation in mice.
Topics: Animals; Antidepressive Agents; Butyric Acid; Calcium-Binding Proteins; Cytokines; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; Gene Expression; Hippocampus; Histones; Lipopolysaccharides; Mice; Mice, Inbred C57BL; Microfilament Proteins; Microglia; Oligonucleotide Array Sequence Analysis; RNA, Messenger; Swimming | 2018 |
High fiber dietary and sodium butyrate attenuate experimental autoimmune hepatitis through regulation of immune regulatory cells and intestinal barrier.
Topics: Animals; Butyric Acid; Cytokines; Dietary Fiber; Disease Models, Animal; Hepatitis, Autoimmune; Interleukin-17; Intestinal Mucosa; Intestines; Liver; Male; Mice; Mice, Inbred C57BL; T-Lymphocytes, Regulatory; Th17 Cells | 2018 |
Anti-Inflammatory Effects of a Mixture of Lactic Acid Bacteria and Sodium Butyrate in Atopic Dermatitis Murine Model.
Topics: Animals; Anti-Inflammatory Agents; Bifidobacterium; Butyric Acid; Dermatitis, Atopic; Disease Models, Animal; Female; Humans; Interleukin-10; Lacticaseibacillus rhamnosus; Lactobacillales; Lactobacillus plantarum; Male; Mice; Mice, Inbred BALB C; Probiotics; T-Lymphocytes, Regulatory; Th1 Cells | 2018 |
Sodium butyrate ameliorates insulin resistance and renal failure in CKD rats by modulating intestinal permeability and mucin expression.
Topics: Animals; Butyric Acid; Disease Models, Animal; Histamine Antagonists; Immunohistochemistry; Insulin Resistance; Intestinal Mucosa; Male; Mucins; Permeability; Rats; Renal Insufficiency, Chronic | 2019 |
Sodium butyrate improves memory and modulates the activity of histone deacetylases in aged rats after the administration of d-galactose.
Topics: Aging; Animals; Brain; Butyric Acid; Disease Models, Animal; DNA Damage; Galactose; Histone Deacetylase Inhibitors; Male; Maze Learning; Memory; Rats; Rats, Wistar | 2018 |
Sodium butyrate reduces high-fat diet-induced non-alcoholic steatohepatitis through upregulation of hepatic GLP-1R expression.
Topics: Adult; Animals; Butyric Acid; Diet, High-Fat; Disease Models, Animal; Disease Progression; Down-Regulation; Female; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor; Hep G2 Cells; Humans; Intestines; Liver; Male; Mice; Mice, Inbred C57BL; Non-alcoholic Fatty Liver Disease | 2018 |
Effect of the HDAC Inhibitor, Sodium Butyrate, on Neurogenesis in a Rat Model of Neonatal Hypoxia-Ischemia: Potential Mechanism of Action.
Topics: Acetylation; Animals; Brain; Butyric Acid; Cell Proliferation; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Doublecortin Protein; Histone Deacetylase Inhibitors; Hypoxia-Ischemia, Brain; Macrophages; MAP Kinase Signaling System; Microglia; Nerve Growth Factors; Neurogenesis; Oligodendroglia; Phenotype; Phosphorylation; Proto-Oncogene Proteins c-akt; Rats, Wistar; Receptors, Nerve Growth Factor; Time Factors; Tubulin | 2019 |
The novel butyrate derivative phenylalanine-butyramide protects from doxorubicin-induced cardiotoxicity.
Topics: Amides; Animals; Antibiotics, Antineoplastic; Apoptosis; Butyrates; Butyric Acid; Cardiotoxicity; Disease Models, Animal; Doxorubicin; Echocardiography; Mice; Mice, Inbred C57BL; Mitochondria; Myocytes, Cardiac; Oxidative Stress; Phenylalanine; Protective Agents; Treatment Outcome | 2019 |
Sodium butyrate ameliorates Corynebacterium pseudotuberculosis infection in RAW264.7 macrophages and C57BL/6 mice.
Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Bacterial Load; Butyric Acid; Cathelicidins; Corynebacterium Infections; Corynebacterium pseudotuberculosis; Disease Models, Animal; Drug Combinations; Female; Gene Expression Regulation, Bacterial; Genes, Bacterial; Macrophages; Mice; Mice, Inbred C57BL; RAW 264.7 Cells; Spleen | 2019 |
Phenylbutyrate is a multifaceted drug that exerts neuroprotective effects and reverses the Alzheimer´s disease-like phenotype of a commonly used mouse model.
Topics: Acetylation; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Biomarkers; Butyric Acid; CA1 Region, Hippocampal; Cells, Cultured; Disease Models, Animal; Female; Histone Deacetylase Inhibitors; Histones; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Nootropic Agents; Phenylbutyrates; Phosphorylation; Protein Processing, Post-Translational; Protein Stability; tau Proteins | 2013 |
Sodium butyrate improves locomotor impairment and early mortality in a rotenone-induced Drosophila model of Parkinson's disease.
Topics: Animals; Animals, Genetically Modified; Butyric Acid; Disease Models, Animal; Drosophila; Histone Deacetylase Inhibitors; Motor Activity; Parkinson Disease, Secondary; Pesticides; Rotenone | 2013 |
Butyric acid attenuates intestinal inflammation in murine DSS-induced colitis model via milk fat globule-EGF factor 8.
Topics: Administration, Rectal; Animals; Antigens, Surface; Butyric Acid; Cell Line; Colitis; Dextran Sulfate; Disease Models, Animal; Histamine Antagonists; Histones; Male; Metagenome; Mice; Mice, Inbred C57BL; Mice, Knockout; Milk Proteins; Promoter Regions, Genetic; Up-Regulation | 2013 |
Effects of sodium butyrate and its synthetic amide derivative on liver inflammation and glucose tolerance in an animal model of steatosis induced by high fat diet.
Topics: Adipose Tissue; Amides; Animals; Butyric Acid; Diet, High-Fat; Disease Models, Animal; Enzyme Activation; Fatty Liver; Glucose; Inflammation; Insulin Resistance; Liver; Male; NF-kappa B; Non-alcoholic Fatty Liver Disease; Rats; Toll-Like Receptors | 2013 |
Effects of sodium butyrate in animal models of mania and depression: implications as a new mood stabilizer.
Topics: Affect; Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Butyric Acid; Disease Models, Animal; Male; Rats; Rats, Wistar | 2013 |
Altered gut microbiota and activity in a murine model of autism spectrum disorders.
Topics: Acetic Acid; Animals; Butyric Acid; Child Development Disorders, Pervasive; Disease Models, Animal; Female; Intestine, Large; Lactic Acid; Male; Mice; Mice, Inbred BALB C; Microbiota; Sex Factors; Valproic Acid | 2014 |
Hizikia fusiformis fractions successfully improve atopic dermatitis indices in anti-CD3-stimulated splenocytes and 2,4-dinitrochlorobenzene-treated BALB/c mice.
Topics: Animals; Antibodies; Butyric Acid; CD3 Complex; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Models, Animal; Immunologic Factors; Lymphocyte Activation; Male; Mice; Mice, Inbred BALB C; NFATC Transcription Factors; Phosphorylation; Phytotherapy; Plant Extracts; Seaweed; Skin; T-Lymphocytes, Helper-Inducer | 2014 |
Protective role of sodium butyrate, a HDAC inhibitor on beta-cell proliferation, function and glucose homeostasis through modulation of p38/ERK MAPK and apoptotic pathways: study in juvenile diabetic rat.
Topics: Animals; Apoptosis; Blotting, Western; Body Weight; Butyric Acid; Cell Proliferation; Diabetes Mellitus, Experimental; Disease Models, Animal; Enzyme Activation; Extracellular Signal-Regulated MAP Kinases; Glucose; Histone Deacetylase Inhibitors; Homeostasis; Hypoglycemic Agents; Insulin-Secreting Cells; Male; Organ Size; Rats; Rats, Sprague-Dawley | 2014 |
Iron supplementation promotes gut microbiota metabolic activity but not colitis markers in human gut microbiota-associated rats.
Topics: Animals; Bacteroides; Biomarkers; Butyric Acid; Cecum; Child; Clostridium; Colitis; Colon; Dietary Supplements; Disease Models, Animal; Feces; Female; Germ-Free Life; Humans; Ileum; Immunity, Mucosal; Iron; Iron Deficiencies; Iron, Dietary; Rats; Rats, Inbred F344; Weight Gain | 2014 |
Repeated treatment with electroconvulsive seizures induces HDAC2 expression and down-regulation of NMDA receptor-related genes through histone deacetylation in the rat frontal cortex.
Topics: Acetylation; Analysis of Variance; Animals; Butyric Acid; Chromatin Immunoprecipitation; Disease Models, Animal; Electroshock; Frontal Lobe; Gene Expression Regulation; Glial Fibrillary Acidic Protein; Histamine Antagonists; Histone Deacetylase 2; Male; Phosphopyruvate Hydratase; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; RNA, Messenger; Seizures; Signal Transduction | 2014 |
Possible additional antidepressant-like mechanism of sodium butyrate: targeting the hippocampus.
Topics: Adaptation, Ocular; Animals; Antidepressive Agents; Butyric Acid; CREB-Binding Protein; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Food Preferences; Gene Expression Regulation; Hindlimb Suspension; Hippocampus; Histone Deacetylases; Male; Mice; Mice, Inbred ICR; Stress, Psychological; Sucrose; Sweetening Agents; Swimming | 2014 |
Sodium butyrate protects against toxin-induced acute liver failure in rats.
Topics: Animals; Biomarkers; Butyric Acid; Chemical and Drug Induced Liver Injury; Cytoprotection; Disease Models, Animal; Galactosamine; HMGB1 Protein; Inflammation Mediators; Interferon-gamma; Intestinal Mucosa; Intestines; Lipopolysaccharides; Liver; Liver Failure, Acute; Permeability; Protective Agents; Rats, Wistar; Serum Albumin; Serum Albumin, Human; Time Factors; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2014 |
Polyglutamine-expanded ataxin-3 impairs long-term depression in Purkinje neurons of SCA3 transgenic mouse by inhibiting HAT and impairing histone acetylation.
Topics: Acetylation; Animals; Ataxin-3; Butyric Acid; Cerebellum; Disease Models, Animal; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Long-Term Synaptic Depression; Machado-Joseph Disease; Mice, Transgenic; Nerve Tissue Proteins; Nuclear Proteins; Peptides; Purkinje Cells; Repressor Proteins; Tissue Culture Techniques; Trinucleotide Repeat Expansion | 2014 |
Beneficial effect of butyrate, Lactobacillus casei and L-carnitine combination in preference to each in experimental colitis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Biomarkers; Butyric Acid; Carnitine; Colitis; Colon; Combined Modality Therapy; Disease Models, Animal; Gastrointestinal Agents; Inflammation Mediators; Lacticaseibacillus casei; Male; Oxidative Stress; Probiotics; Rats, Wistar; Time Factors; Trinitrobenzenesulfonic Acid | 2014 |
Sodium butyrate functions as an antidepressant and improves cognition with enhanced neurotrophic expression in models of maternal deprivation and chronic mild stress.
Topics: Analysis of Variance; Animals; Antidepressive Agents; Butyric Acid; Cognition Disorders; Depression; Disease Models, Animal; Exploratory Behavior; Gene Expression Regulation; Hippocampus; Intercellular Signaling Peptides and Proteins; Male; Maternal Deprivation; Rats; Rats, Wistar; Recognition, Psychology; Stress, Psychological; Swimming | 2014 |
Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism.
Topics: Acetylation; Animals; Autistic Disorder; Butyric Acid; CA1 Region, Hippocampal; Dendritic Spines; Disease Models, Animal; Exploratory Behavior; Female; Histone Deacetylase Inhibitors; Histones; Male; Mice; Pregnancy; Prenatal Exposure Delayed Effects; Valproic Acid | 2014 |
[Sodium butyrate inhibits HMGB1 expression and release and attenuates concanavalin A-induced acute liver injury in mice].
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Butyric Acid; Chemical and Drug Induced Liver Injury; Concanavalin A; Disease Models, Animal; HMGB1 Protein; Interferon-gamma; Liver; Mice; Tumor Necrosis Factor-alpha | 2014 |
Histone deacetylase inhibitors reverse manic-like behaviors and protect the rat brain from energetic metabolic alterations induced by ouabain.
Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Brain; Butyric Acid; Citric Acid Cycle; Disease Models, Animal; Energy Metabolism; Exploratory Behavior; Histone Deacetylase Inhibitors; Lithium; Male; Motor Activity; Ouabain; Rats; Rats, Wistar; Valproic Acid | 2015 |
Sodium butyrate and mood stabilizers block ouabain-induced hyperlocomotion and increase BDNF, NGF and GDNF levels in brain of Wistar rats.
Topics: Affect; Animals; Antimanic Agents; Bipolar Disorder; Brain-Derived Neurotrophic Factor; Butyric Acid; Disease Models, Animal; Glial Cell Line-Derived Neurotrophic Factor; Hippocampus; Histamine Antagonists; Lithium Compounds; Locomotion; Male; Motor Activity; Nerve Growth Factor; Ouabain; Prefrontal Cortex; Rats; Rats, Wistar; Treatment Outcome; Valproic Acid | 2015 |
Antidepressant-like effect of sodium butyrate is associated with an increase in TET1 and in 5-hydroxymethylation levels in the Bdnf gene.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Butyric Acid; Depressive Disorder; Dioxygenases; Disease Models, Animal; DNA Methylation; Histone Deacetylase Inhibitors; Male; Prefrontal Cortex; Rats; Up-Regulation | 2014 |
Intraperitoneal administration of butyrate prevents the severity of acetic acid colitis in rats.
Topics: Acetic Acid; Administration, Oral; Administration, Rectal; Animals; Butyric Acid; Colitis, Ulcerative; Disease Models, Animal; Goblet Cells; Injections, Intraperitoneal; Intestinal Mucosa; Male; Rats; Rats, Wistar | 2015 |
Histone deacetylases inhibitors effects on Cryptococcus neoformans major virulence phenotypes.
Topics: Animals; Butyric Acid; Cell Division; Cryptococcus neoformans; Disease Models, Animal; Fungal Capsules; Histone Deacetylase Inhibitors; Hydroxamic Acids; Lepidoptera; Melanins; Microbial Viability; Phenotype; Phospholipases; Survival Analysis; Temperature; Virulence | 2015 |
Sodium Butyrate, a Histone Deacetylase Inhibitor, Reverses Behavioral and Mitochondrial Alterations in Animal Models of Depression Induced by Early- or Late-life Stress.
Topics: Animals; Animals, Newborn; Butyric Acid; Citric Acid Cycle; Corpus Striatum; Depression; Disease Models, Animal; Electron Transport Chain Complex Proteins; Exploratory Behavior; Female; Gene Expression Regulation, Enzymologic; Histone Deacetylase Inhibitors; Immobility Response, Tonic; Malate Dehydrogenase; Male; Maternal Deprivation; Rats; Rats, Wistar; Stress, Psychological; Succinate Dehydrogenase; Swimming | 2015 |
Sodium butyrate alleviates adipocyte inflammation by inhibiting NLRP3 pathway.
Topics: Adipocytes; Animals; Anti-Inflammatory Agents; Butyric Acid; Carrier Proteins; Disease Models, Animal; Inflammation; Male; Mice; Mice, Knockout; NLR Family, Pyrin Domain-Containing 3 Protein; Signal Transduction | 2015 |
Bactericidal Activity of Ceragenin CSA-13 in Cell Culture and in an Animal Model of Peritoneal Infection.
Topics: Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; Biological Availability; Butyric Acid; Cathelicidins; Cell Line; Disease Models, Animal; Epithelial Cells; Female; Fluorescent Dyes; Humans; Injections, Intraperitoneal; Kidney; Liver; Lung; Mice; Mice, Nude; Microbial Sensitivity Tests; Peritonitis; Pseudomonas aeruginosa; Pseudomonas Infections; Respiratory Mucosa; Steroids | 2015 |
Sodium butyrate attenuates social behavior deficits and modifies the transcription of inhibitory/excitatory genes in the frontal cortex of an autism model.
Topics: Animals; Autism Spectrum Disorder; Avoidance Learning; Behavior, Animal; Butyric Acid; Cyclic AMP Response Element-Binding Protein; Disease Models, Animal; Frontal Lobe; Grooming; Histone Deacetylase Inhibitors; Mice; Phosphorylation; Social Behavior; Transcription, Genetic | 2016 |
Sodium butyrate has an antimanic effect and protects the brain against oxidative stress in an animal model of mania induced by ouabain.
Topics: Animals; Antimanic Agents; Antioxidants; Bipolar Disorder; Brain; Butyric Acid; Catalase; Disease Models, Animal; Hippocampus; Hyperkinesis; Male; Ouabain; Oxidative Stress; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2016 |
Epigenetic regulation of BDNF in the learned helplessness-induced animal model of depression.
Topics: Animals; Antidepressive Agents; Brain-Derived Neurotrophic Factor; Butyric Acid; Depression; Disease Models, Animal; Dose-Response Relationship, Drug; Epigenesis, Genetic; Exons; Helplessness, Learned; Hindlimb Suspension; Hippocampus; Histone Deacetylase Inhibitors; Histone Deacetylases; Imipramine; Male; Mice; Mice, Inbred C57BL; RNA, Small Interfering; Swimming; Valproic Acid | 2016 |
Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein.
Topics: Animals; Apoptosis; Butyric Acid; Carcinoma, Hepatocellular; Cell Compartmentation; Cell Line, Tumor; Cell Nucleus; Cell Proliferation; Cytoplasm; Disease Models, Animal; Exportin 1 Protein; Gene Expression Regulation, Neoplastic; Humans; Karyopherins; Liver Neoplasms; Male; Protein Binding; Rats, Wistar; Receptors, Cytoplasmic and Nuclear; Triglycerides; Tumor Suppressor Protein p53 | 2016 |
Histone deacetylase inhibition prevents the impairing effects of hippocampal gastrin-releasing peptide receptor antagonism on memory consolidation and extinction.
Topics: Animals; Avoidance Learning; Bombesin; Brain-Derived Neurotrophic Factor; Butyric Acid; Disease Models, Animal; Drug Administration Schedule; Extinction, Psychological; Hippocampus; Histone Deacetylases; Male; Memory Consolidation; Memory Disorders; Peptide Fragments; Rats; Rats, Wistar; Receptors, Bombesin; Statistics, Nonparametric | 2016 |
Accelerated dysbiosis of gut microbiota during aggravation of DSS-induced colitis by a butyrate-producing bacterium.
Topics: Adult; Animals; Butyric Acid; Clostridiales; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Genome, Bacterial; High-Throughput Nucleotide Sequencing; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Microbial Interactions | 2016 |
Dual influences of early-life maternal deprivation on histone deacetylase activity and recognition memory in rats.
Topics: Acetylation; Animals; Brain-Derived Neurotrophic Factor; Butyric Acid; Disease Models, Animal; Hippocampus; Histone Deacetylase Inhibitors; Histone Deacetylases; Histones; Male; Maternal Deprivation; Memory Disorders; Nootropic Agents; Rats, Wistar; Recognition, Psychology; Stress, Psychological | 2017 |
Control of Clostridium perfringens-induced necrotic enteritis in broilers by target-released butyric acid, fatty acids and essential oils.
Topics: Animals; Butyric Acid; Chickens; Clostridium Infections; Clostridium perfringens; Disease Models, Animal; Drug Compounding; Enteritis; Necrosis; Oils, Volatile; Poultry Diseases | 2010 |
Mesenchymal stem cells in renal function recovery after acute kidney injury: use of a differentiating agent in a rat model.
Topics: Acute Kidney Injury; Animals; Butyric Acid; Cell Differentiation; Cytokines; Disease Models, Animal; Humans; Hyaluronic Acid; Immunohistochemistry; Kidney; Kidney Function Tests; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal Stem Cells; Rats; Rats, Sprague-Dawley; Recovery of Function | 2011 |
Behavioral and neurochemical effects of sodium butyrate in an animal model of mania.
Topics: Animals; Antimanic Agents; Behavior, Animal; Bipolar Disorder; Brain; Butyric Acid; Central Nervous System Stimulants; Dextroamphetamine; Disease Models, Animal; Histone Deacetylase Inhibitors; Hyperkinesis; Male; Motor Activity; Rats; Rats, Wistar | 2011 |
Roles of mucosal bacteria and succinic acid in colitis caused by dextran sulfate sodium in mice.
Topics: Acetates; Animals; Bacteroidaceae; Bacteroides; Butyric Acid; Carboxylic Acids; Cecum; Colitis; Colitis, Ulcerative; Colon; Dextran Sulfate; Disease Models, Animal; Feces; Female; Germ-Free Life; Intestinal Mucosa; Male; Mice; Mice, Inbred CBA; Mice, Inbred Strains; Propionates; Rectum; Succinic Acid | 2000 |
Variable effects of short chain fatty acids and lactic acid in inducing intestinal mucosal injury in newborn rats.
Topics: Acetic Acid; Animals; Animals, Newborn; Butyric Acid; Colon; Disease Models, Animal; Dose-Response Relationship, Drug; Fatty Acids, Volatile; Hydrogen-Ion Concentration; Intestinal Mucosa; Lactic Acid; Random Allocation; Rats; Rats, Sprague-Dawley | 2002 |
A comparative study of the influence of differing barley brans on DMH-induced intestinal tumours in male Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; Animals; Antineoplastic Agents; Body Weight; Butyrates; Butyric Acid; Carcinogens; Cellulose; Dietary Fiber; Dimethylhydrazines; Disease Models, Animal; Hordeum; Incidence; Intestinal Neoplasms; Male; Organ Size; Rats; Rats, Sprague-Dawley; Triticum | 1996 |
The effect of carnitine on ketogenesis in perfused livers from juvenile visceral steatosis mice with systemic carnitine deficiency.
Topics: Animals; Butyrates; Butyric Acid; Caprylates; Carnitine; Disease Models, Animal; Fatty Liver; In Vitro Techniques; Ketone Bodies; Liver; Mice; Mice, Mutant Strains; Oleic Acid; Perfusion | 1997 |
Clostridial pathogenicity in experimental necrotising enterocolitis in gnotobiotic quails and protective role of bifidobacteria.
Topics: Animals; Bifidobacterium; Butyric Acid; Cecum; Clostridioides difficile; Clostridium; Clostridium perfringens; Coturnix; Disease Models, Animal; Enterocolitis, Necrotizing; Feces; Fermentation; Germ-Free Life; Humans; Hydrogen; Infant; Infant, Newborn; Lactose; Virulence | 1998 |
Hydroxyurea-induced HbF production in anemic primates: augmentation by erythropoietin, hematopoietic growth factors, and sodium butyrate.
Topics: Administration, Oral; Anemia; Animals; Bloodletting; Butyrates; Butyric Acid; Cell Division; Chromatography, High Pressure Liquid; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Therapy, Combination; Erythrocytes; Erythropoietin; Female; Fetal Hemoglobin; Granulocyte-Macrophage Colony-Stimulating Factor; Hematocrit; Hematopoietic Cell Growth Factors; Hydroxyurea; Injections, Intravenous; Interleukin-3; Macaca mulatta; Reticulocytes; Time Factors | 1992 |
Beige mouse mast cells generated in vitro: ultrastructural analysis of maturation induced by sodium butyrate and of IgE-mediated, antigen-dependent degranulation.
Topics: Animals; Bone Marrow; Butyrates; Butyric Acid; Cell Line; Chediak-Higashi Syndrome; Cytoplasmic Granules; Disease Models, Animal; Exocytosis; Immunoglobulin E; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Mutant Strains | 1987 |