butyric acid has been researched along with Disease Exacerbation in 11 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To understand the various effects of SCFAs on breast carcinogenesis, we investigated the effect of sodium butyrate (NaB) and sodium propionate (NaP) in MCF-7 cell line." | 7.96 | Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7. ( El Boustany, C; El-Hakim, S; Elnar, AA; Ibrahim, JN; Safi, R; Semaan, J, 2020) |
| "To understand the various effects of SCFAs on breast carcinogenesis, we investigated the effect of sodium butyrate (NaB) and sodium propionate (NaP) in MCF-7 cell line." | 3.96 | Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7. ( El Boustany, C; El-Hakim, S; Elnar, AA; Ibrahim, JN; Safi, R; Semaan, J, 2020) |
| " Liver damage, markers of glucose metabolism, inflammation, intestinal barrier function and melatonin metabolism were determined." | 3.96 | Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis. ( Baumann, A; Bergheim, I; Brandt, A; Burkard, M; Jin, CJ; Nier, A; Sellmann, C; Venturelli, S, 2020) |
| "The pathophysiology of type 1 diabetes has been linked to altered gut microbiota and more specifically to a shortage of intestinal production of the short-chain fatty acid (SCFA) butyrate, which may play key roles in maintaining intestinal epithelial integrity and in human and gut microbial metabolism." | 2.94 | Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial. ( Bekkering, S; Berkvens, A; Bindraban, R; Dallinga-Thie, GM; Davids, M; de Groot, PF; Duinkerken, G; Herrema, H; Hoekstra, JBL; Holleman, F; Hutten, B; Imangaliyev, S; Keij, FM; Kemper, EM; Kroon, J; Levels, JHM; Levin, E; Netea, M; Nieuwdorp, M; Nikolic, T; Roep, BO; Simsek, S; Stroes, ESG; van Hoorn, FA; van Raalte, DH; Winkelmeijer, M, 2020) |
| "Cancer cachexia is mainly characterized by wasting of skeletal muscles and fat and body weight loss, along with severe complications of major organs like liver, heart, brain and bone." | 1.72 | Systemic study of selected histone deacetylase inhibitors in cardiac complications associated with cancer cachexia. ( Bora, V; Goyal, RK; Johar, K; Patel, BM; Patel, D, 2022) |
| "Similarly, in the NAFLD mouse model, mice fed with a high-fat diet showed reduced hepatic GLP-1R expression, which was reversed by NaB treatment and accompanied by markedly alleviated liver steatosis." | 1.48 | Sodium butyrate reduces high-fat diet-induced non-alcoholic steatohepatitis through upregulation of hepatic GLP-1R expression. ( Chen, YW; Fan, JG; Liu, XL; Pan, Q; Xin, FZ; Yang, RX; Zhao, ZH; Zhou, D; Zhou, H, 2018) |
| "Butyric acid (BA) is a periodontopathic metabolite that activates several stress-related signals and, likewise, induce neurite retraction." | 1.43 | Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease progression. ( Cueno, ME; Kamimoto, A; Kamio, N; Kurita-Ochiai, T; Ochiai, K; Saito, Y; Seki, K, 2016) |
| "Thus, we have tested polyposis coli Pc/AA adenoma cells, Caco-2, HT-29 and LS174T adenocarcinoma cell lines." | 1.31 | Deregulated expression of homeobox-containing genes, HOXB6, B8, C8, C9, and Cdx-1, in human colon cancer cell lines. ( Chastre, E; Gazit, A; Gespach, C; Halperin, M; Mashiah, P; Vider, BZ; Yaniv, A; Zimber, A, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 5 (45.45) | 2.80 |
| Authors | Studies |
|---|---|
| Bora, V | 1 |
| Patel, D | 1 |
| Johar, K | 1 |
| Goyal, RK | 1 |
| Patel, BM | 1 |
| de Groot, PF | 1 |
| Nikolic, T | 1 |
| Imangaliyev, S | 1 |
| Bekkering, S | 1 |
| Duinkerken, G | 1 |
| Keij, FM | 1 |
| Herrema, H | 1 |
| Winkelmeijer, M | 1 |
| Kroon, J | 1 |
| Levin, E | 1 |
| Hutten, B | 1 |
| Kemper, EM | 1 |
| Simsek, S | 1 |
| Levels, JHM | 1 |
| van Hoorn, FA | 1 |
| Bindraban, R | 1 |
| Berkvens, A | 1 |
| Dallinga-Thie, GM | 1 |
| Davids, M | 1 |
| Holleman, F | 1 |
| Hoekstra, JBL | 1 |
| Stroes, ESG | 1 |
| Netea, M | 1 |
| van Raalte, DH | 1 |
| Roep, BO | 1 |
| Nieuwdorp, M | 1 |
| Semaan, J | 1 |
| El-Hakim, S | 1 |
| Ibrahim, JN | 1 |
| Safi, R | 1 |
| Elnar, AA | 1 |
| El Boustany, C | 1 |
| Baumann, A | 1 |
| Jin, CJ | 1 |
| Brandt, A | 1 |
| Sellmann, C | 1 |
| Nier, A | 1 |
| Burkard, M | 1 |
| Venturelli, S | 1 |
| Bergheim, I | 1 |
| Jacob, N | 1 |
| Jaiswal, S | 1 |
| Maheshwari, D | 1 |
| Nallabelli, N | 1 |
| Khatri, N | 1 |
| Bhatia, A | 1 |
| Bal, A | 1 |
| Malik, V | 1 |
| Verma, S | 1 |
| Kumar, R | 1 |
| Sachdeva, N | 1 |
| Zhou, D | 1 |
| Chen, YW | 1 |
| Zhao, ZH | 1 |
| Yang, RX | 1 |
| Xin, FZ | 1 |
| Liu, XL | 1 |
| Pan, Q | 1 |
| Zhou, H | 1 |
| Fan, JG | 1 |
| Seki, K | 1 |
| Cueno, ME | 1 |
| Kamio, N | 1 |
| Saito, Y | 1 |
| Kamimoto, A | 1 |
| Kurita-Ochiai, T | 1 |
| Ochiai, K | 2 |
| Lazarova, DL | 1 |
| Bordonaro, M | 1 |
| Imai, K | 1 |
| Okamoto, T | 1 |
| Qiqiang, L | 1 |
| Huanxin, M | 1 |
| Xuejun, G | 1 |
| Vider, BZ | 1 |
| Zimber, A | 1 |
| Chastre, E | 1 |
| Gespach, C | 1 |
| Halperin, M | 1 |
| Mashiah, P | 1 |
| Yaniv, A | 1 |
| Gazit, A | 1 |
1 review available for butyric acid and Disease Exacerbation
| Article | Year |
|---|---|
Vimentin, colon cancer progression and resistance to butyrate and other HDACis.
Topics: Animals; Butyric Acid; Colonic Neoplasms; Disease Progression; Drug Resistance, Neoplasm; Histone De | 2016 |
1 trial available for butyric acid and Disease Exacerbation
| Article | Year |
|---|---|
Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial.
Topics: Adaptive Immunity; Administration, Oral; Adult; Autoimmunity; Butyric Acid; Diabetes Mellitus, Type | 2020 |
9 other studies available for butyric acid and Disease Exacerbation
| Article | Year |
|---|---|
Systemic study of selected histone deacetylase inhibitors in cardiac complications associated with cancer cachexia.
Topics: Animals; Benzamides; Butyric Acid; Cachexia; Cell Line, Tumor; Disease Models, Animal; Disease Progr | 2022 |
Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7.
Topics: Apoptosis; Breast Neoplasms; Butyric Acid; Carcinogenesis; Cell Cycle; Cell Proliferation; Disease P | 2020 |
Oral Supplementation of Sodium Butyrate Attenuates the Progression of Non-Alcoholic Steatohepatitis.
Topics: Animals; Butyric Acid; Cholesterol, Dietary; Diet, High-Fat; Dietary Supplements; Disease Models, An | 2020 |
Butyrate induced Tregs are capable of migration from the GALT to the pancreas to restore immunological tolerance during type-1 diabetes.
Topics: Animals; Butyric Acid; Cell Movement; Diabetes Mellitus, Type 1; Disease Progression; Female; Immune | 2020 |
Sodium butyrate reduces high-fat diet-induced non-alcoholic steatohepatitis through upregulation of hepatic GLP-1R expression.
Topics: Adult; Animals; Butyric Acid; Diet, High-Fat; Disease Models, Animal; Disease Progression; Down-Regu | 2018 |
Varying butyric acid amounts induce different stress- and cell death-related signals in nerve growth factor-treated PC12 cells: implications in neuropathic pain absence during periodontal disease progression.
Topics: Animals; Apoptosis; Butyric Acid; Disease Progression; Nerve Growth Factor; Neuralgia; Neurites; Oxi | 2016 |
Reactivation of latent HIV-1 infection by the periodontopathic bacterium Porphyromonas gingivalis involves histone modification.
Topics: Bacteroidaceae Infections; Butyric Acid; Cell Line; Cell-Free System; Chromatin; Disease Progression | 2009 |
Longitudinal study of volatile fatty acids in the gingival crevicular fluid of patients with periodontitis before and after nonsurgical therapy.
Topics: Adult; Aged; Bacteria, Anaerobic; Butyric Acid; Case-Control Studies; Chronic Periodontitis; Dental | 2012 |
Deregulated expression of homeobox-containing genes, HOXB6, B8, C8, C9, and Cdx-1, in human colon cancer cell lines.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Butyric Acid; Cell Count; Cell Differentiation; Colonic | 2000 |