butyric acid has been researched along with Di Guglielmo Disease in 36 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present study explores possible genetic mechanisms involved in AZT-induced anemia by evaluating the effects of AZT on globin gene expression at both the transcriptional and the translational levels in butyric acid-induced K-562 human erythroleukemia cells." | 3.68 | 3'-Azido-3'-deoxythymidine inhibits globin gene transcription in butyric acid-induced K-562 human leukemia cells. ( Sommadossi, JP; Weidner, DA, 1990) |
| "Unlike other chemically induced erythroleukemia cell differentiation, no c-myc mRNA down-regulation was observed in the early phases of drug treatment." | 1.30 | Protein tyrosine phosphatase-dependent activation of beta-globin and delta-aminolevulinic acid synthase genes in the camptothecin-induced IW32 erythroleukemia cell differentiation. ( Liu, JH; Wang, FF; Wang, MC, 1997) |
| "Butyric acid (BA) was shown to induce hemoglobinization of K562 cells in a dose- and time-dependent manner." | 1.30 | Time-course of butyric acid-induced differentiation in human K562 leukemic cell line: rapid increase in gamma-globin, porphobilinogen deaminase and NF-E2 mRNA levels. ( Chénais, B; Jeannesson, P; Molle, I; Trentesaux, C, 1997) |
| "Human erythroleukemia HEL cells showed AQP1 transcript expression on RNase protection assay." | 1.30 | Isolation of the human aquaporin-1 promoter and functional characterization in human erythroleukemia cell lines. ( Umenishi, F; Verkman, AS, 1998) |
| "The human erythroleukemia (K562) cell line undergoes megakaryocytic differentiation and cessation of proliferation when treated with phorbol myristate acetate (PMA)." | 1.29 | Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation. ( Baumgardner, GP; Burns, DJ; Fields, AP; Murray, NR, 1993) |
| "Following treatment of mouse erythroleukemia (MEL) cells with dimethyl sulfoxide and other typical erythroid inducing agents, the profile of cellular phosphotyrosine-containing proteins was drastically altered." | 1.28 | Alteration of phosphotyrosine-containing proteins at the early stage of erythroid differentiation of mouse erythroleukemia (MEL) cells. ( Kume, T; Oishi, M; Watanabe, T, 1992) |
| "Histone acetylation of Murine Erythroleukemia Cells (MELC) has been re-examined." | 1.27 | Increase in histone acetylation and transitions in histone variants during Friend cell differentiation. ( Helliger, W; Leiter, JM; Puschendorf, B, 1984) |
| "K562 is an established human erythroleukemia cell line, inducible for hemoglobin synthesis by a variety of compounds including n-butyrate." | 1.27 | K562 human erythroleukemia cell variants resistant to growth inhibition by butyrate have deficient histone acetylation. ( Farley, BA; Kosciolek, B; La Bella, S; Ohlsson-Wilhelm, BM; Rowley, PT, 1984) |
| "Friend erythroleukemia cells can be induced to undergo erythroid differentiation by a variety of unrelated compounds." | 1.27 | Depletion of sodium butyrate from the culture medium of Friend erythroleukemia cells undergoing differentiation. ( Friend, C; Holland, JG; Pogo, BG; Zajac-Kaye, M, 1987) |
| "The integrated proviral DNA in Friend erythroleukemia cells was examined by Southern hybridization with a cloned Friend virus (F-MuLV) probe at days 1 and 4 following inducer treatment, as well as on day 6 at which time the cells had remained for 48 h in inducer free medium." | 1.27 | Induction of differentiation in Friend erythroleukemia cells with dimethyl sulfoxide, hexamethylene bisacetamide and sodium butyrate is not accompanied by changes in proviral DNA or its expression. ( Brown, E; Friend, C; Zajac-Kaye, M, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (33.33) | 18.7374 |
| 1990's | 22 (61.11) | 18.2507 |
| 2000's | 1 (2.78) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Landi, M | 1 |
| Catelani, G | 1 |
| D'Andrea, F | 1 |
| Ghidini, E | 1 |
| Amari, G | 1 |
| Paola, P | 1 |
| Bianchi, N | 1 |
| Gambari, R | 1 |
| Berkovitch-Luria, G | 1 |
| Yakobovitch, S | 1 |
| Weitman, M | 1 |
| Nudelman, A | 1 |
| Rozic, G | 1 |
| Rephaeli, A | 1 |
| Malik, Z | 1 |
| Hsu, KH | 1 |
| Friedman, H | 1 |
| Zucker, RM | 3 |
| Decal, DL | 2 |
| Whittington, KB | 2 |
| Bin, X | 1 |
| DiLiberto, M | 1 |
| Rifkind, RA | 2 |
| Marks, PA | 1 |
| Levenson, R | 1 |
| Macara, I | 1 |
| Cantley, L | 1 |
| Housman, D | 1 |
| Leiter, JM | 1 |
| Helliger, W | 3 |
| Puschendorf, B | 2 |
| Ohlsson-Wilhelm, BM | 2 |
| Farley, BA | 1 |
| Kosciolek, B | 1 |
| La Bella, S | 1 |
| Rowley, PT | 2 |
| Chen, YL | 1 |
| Wu, RT | 1 |
| Grässel, S | 1 |
| Cohen, IR | 1 |
| Murdoch, AD | 1 |
| Eichstetter, I | 1 |
| Iozzo, RV | 1 |
| Fuchs, O | 1 |
| Safaya, S | 1 |
| Ibrahim, A | 1 |
| Rieder, RF | 1 |
| Chen, ZX | 1 |
| Breitman, TR | 1 |
| Murray, NR | 1 |
| Baumgardner, GP | 1 |
| Burns, DJ | 1 |
| Fields, AP | 1 |
| Kawasaki, N | 1 |
| Morimoto, K | 1 |
| Tanimoto, T | 1 |
| Hayakawa, T | 1 |
| Rafferty, SP | 1 |
| Domachowske, JB | 1 |
| Malech, HL | 1 |
| Lindner, H | 2 |
| Sarg, B | 1 |
| Meraner, C | 1 |
| Wang, MC | 1 |
| Liu, JH | 1 |
| Wang, FF | 1 |
| Chénais, B | 1 |
| Molle, I | 1 |
| Trentesaux, C | 1 |
| Jeannesson, P | 1 |
| Umenishi, F | 1 |
| Verkman, AS | 1 |
| Nathan, I | 1 |
| Ben-Valid, I | 1 |
| Henzel, R | 1 |
| Masalha, H | 1 |
| Baram, SN | 1 |
| Dvilansky, A | 1 |
| Parola, AH | 1 |
| Rivero, JA | 1 |
| Adunyah, SE | 1 |
| Grdisa, M | 1 |
| Watanabe, T | 1 |
| Kume, T | 1 |
| Oishi, M | 1 |
| Grübl-Knosp, O | 1 |
| Järvinen, M | 2 |
| Andersson, LC | 1 |
| Virtanen, I | 1 |
| Glauber, JG | 1 |
| Wandersee, NJ | 1 |
| Little, JA | 1 |
| Ginder, GD | 1 |
| Weidner, DA | 1 |
| Sommadossi, JP | 1 |
| Zhang, JW | 1 |
| Raich, N | 1 |
| Enver, T | 1 |
| Anagnou, NP | 1 |
| Stamatoyannopoulos, G | 1 |
| Corin, RE | 1 |
| Haspel, HC | 1 |
| Peretz, AM | 1 |
| Sonenberg, M | 1 |
| Friend, C | 2 |
| Zajac-Kaye, M | 2 |
| Holland, JG | 1 |
| Pogo, BG | 1 |
| Brown, E | 1 |
| Umlas, ME | 1 |
36 other studies available for butyric acid and Di Guglielmo Disease
| Article | Year |
|---|---|
Synthesis of glycose carbamides and evaluation of the induction of erythroid differentiation of human erythroleukemic K562 cells.
Topics: Antineoplastic Agents; Cell Differentiation; Drug Screening Assays, Antitumor; Erythroid Cells; Gala | 2009 |
A multifunctional 5-aminolevulinic acid derivative induces erythroid differentiation of K562 human erythroleukemic cells.
Topics: alpha-Globins; Aminolevulinic Acid; Butyric Acid; Cell Differentiation; Cell Proliferation; Erythroi | 2012 |
Dexamethasone inhibition of DMSO-induced transglutaminase activity and differentiation of leukemic cells.
Topics: Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dexamethasone; Dimethyl Sulfoxide | 1984 |
5-Azacytidine increases the synthesis of embryonic hemoglobin (E2) in murine erythroleukemic cells.
Topics: Animals; Azacitidine; Butyrates; Butyric Acid; Cell Differentiation; Dimethyl Sulfoxide; Fetal Hemog | 1983 |
Releasing effect of thymidine on G1 phase arrest of erythroleukemia cells caused by FUDR and HMBA.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Clone Cells; Dact | 1984 |
Ionic regulation of MEL cell commitment.
Topics: Animals; Biological Transport, Active; Butyrates; Butyric Acid; Calcium; Cell Differentiation; Cell | 1983 |
Increase in histone acetylation and transitions in histone variants during Friend cell differentiation.
Topics: Acetylation; Animals; Butyrates; Butyric Acid; Cell Differentiation; Cells, Cultured; Dimethyl Sulfo | 1984 |
K562 human erythroleukemia cell variants resistant to growth inhibition by butyrate have deficient histone acetylation.
Topics: Acetylation; Benzidines; Butyrates; Butyric Acid; Cell Division; Electrophoresis, Polyacrylamide Gel | 1984 |
Cell cycle dependency of tumor promoter on murine erythroleukemic cells.
Topics: Animals; Benzidines; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Clone Cells; Dimethyl Sulfoxi | 1981 |
Altered queuine modification of transfer RNA involved in the differentiation of human K562 erythroleukemia cells in the presence of distinct differentiation inducers.
Topics: Aspartate-tRNA Ligase; Azacitidine; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Ce | 1994 |
The proteoglycan perlecan is expressed in the erythroleukemia cell line K562 and is upregulated by sodium butyrate and phorbol ester.
Topics: Base Sequence; Butyrates; Butyric Acid; Cell Differentiation; Chondroitinases and Chondroitin Lyases | 1995 |
Iron-responsive element-binding protein mRNA levels during erythroid differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Cell Differentiation; Dimethyl Sulfoxide; Enzyme Induc | 1995 |
Augmentation of gamma-globin gene promoter activity by carboxylic acids and components of the human beta-globin locus control region.
Topics: Animals; Base Sequence; Butyrates; Butyric Acid; Carboxylic Acids; Enhancer Elements, Genetic; Gene | 1994 |
Tributyrin: a prodrug of butyric acid for potential clinical application in differentiation therapy.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dose-Response Relationship, Drug; Drug Int | 1994 |
Protein kinase C isotypes in human erythroleukemia (K562) cell proliferation and differentiation. Evidence that beta II protein kinase C is required for proliferation.
Topics: Base Sequence; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Humans; Isoenzymes; Leu | 1993 |
Control of hemoglobin synthesis in erythroid differentiating K562 cells. I. Role of iron in erythroid cell heme synthesis.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Butyrates; Butyric Acid; Cell Differentiation; Ce | 1996 |
Inhibition of hemoglobin expression by heterologous production of nitric oxide synthase in the K562 erythroleukemic cell line.
Topics: 5-Aminolevulinate Synthetase; Aminolevulinic Acid; Base Sequence; Butyrates; Butyric Acid; Gene Expr | 1996 |
Separation of acetylated core histones by hydrophilic-interaction liquid chromatography.
Topics: Acetylation; Acids; Animals; Butyrates; Butyric Acid; Chromatography, High Pressure Liquid; Chromato | 1996 |
Protein tyrosine phosphatase-dependent activation of beta-globin and delta-aminolevulinic acid synthase genes in the camptothecin-induced IW32 erythroleukemia cell differentiation.
Topics: 5-Aminolevulinate Synthetase; Animals; Antineoplastic Agents, Phytogenic; Butyrates; Butyric Acid; C | 1997 |
Time-course of butyric acid-induced differentiation in human K562 leukemic cell line: rapid increase in gamma-globin, porphobilinogen deaminase and NF-E2 mRNA levels.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Division; DNA-Binding Proteins; Erythroid-Specif | 1997 |
Isolation of the human aquaporin-1 promoter and functional characterization in human erythroleukemia cell lines.
Topics: Aquaporin 1; Aquaporins; Base Sequence; Blood Group Antigens; Butyrates; Butyric Acid; Cell Differen | 1998 |
Alterations in membrane lipid dynamics of leukemic cells undergoing growth arrest and differentiation: dependency on the inducing agent.
Topics: Butyrates; Butyric Acid; Calcitriol; Cell Differentiation; Cell Division; Diphenylhexatriene; Fluore | 1998 |
Sodium butyrate stimulates PKC activation and induces differential expression of certain PKC isoforms during erythroid differentiation.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Enzyme Activation; Enzyme Induction; F | 1998 |
Alteration of phosphotyrosine-containing proteins during differentiation of chicken erythroleukemia cells (HD3).
Topics: 1-Methyl-3-isobutylxanthine; Animals; Butyric Acid; Cell Differentiation; Chickens; Enzyme Inhibitor | 1998 |
Alteration of phosphotyrosine-containing proteins at the early stage of erythroid differentiation of mouse erythroleukemia (MEL) cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Line | 1992 |
Alteration in proportions of histone H1 variants during the differentiation of murine erythroleukaemic cells.
Topics: Acetamides; Animals; Antineoplastic Agents; Butyrates; Butyric Acid; Cell Differentiation; Cell Divi | 1992 |
K562 erythroleukemia cells express cytokeratins 8, 18, and 19 and epithelial membrane antigen that disappear after induced differentiation.
Topics: Blotting, Western; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Epithelial Cells | 1990 |
5'-flanking sequences mediate butyrate stimulation of embryonic globin gene expression in adult erythroid cells.
Topics: Acetylation; Animals; Butyrates; Butyric Acid; Chick Embryo; DNA; Erythrocytes; Gene Expression Regu | 1991 |
3'-Azido-3'-deoxythymidine inhibits globin gene transcription in butyric acid-induced K-562 human leukemia cells.
Topics: Anemia; Butyrates; Butyric Acid; Dose-Response Relationship, Drug; Globins; Hemoglobins; Humans; Leu | 1990 |
Vimentin in human erythroleukemia (HEL) cells is modulated with differentiation inducers.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cytoskeleton; Fluorescent Antibody Technique; Hemin; | 1990 |
Butyrate induces expression of transfected human fetal and endogenous mouse embryonic globin genes in GM 979 erythroleukemia cells.
Topics: Acetamides; Animals; Blotting, Southern; Butyrates; Butyric Acid; Dimethyl Sulfoxide; Gene Expressio | 1990 |
Antagonistic effect of butyrate on hexamethylene bisacetamide induced differentiation of murine erythroleukemia cells.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Cell Cycle; Cell Differentiation; Dose-Response Relati | 1986 |
Depletion of sodium butyrate from the culture medium of Friend erythroleukemia cells undergoing differentiation.
Topics: Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Culture Media; DNA | 1987 |
Induction of differentiation in Friend erythroleukemia cells with dimethyl sulfoxide, hexamethylene bisacetamide and sodium butyrate is not accompanied by changes in proviral DNA or its expression.
Topics: Acetamides; Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Dimethyl Sulfoxide; D | 1986 |
Differential hemoglobin synthesis in murine erythroleukemic cells: hemin effects.
Topics: Animals; Butyrates; Butyric Acid; Cell Differentiation; Clone Cells; Friend murine leukemia virus; H | 1987 |
Demonstration of commitment by K562 human erythroleukemia cells.
Topics: Benzidines; Butyrates; Butyric Acid; Cell Adhesion; Cell Differentiation; Cell Division; Cell Line; | 1985 |