butyric acid has been researched along with Crohn Disease in 9 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Crohn Disease: A chronic transmural inflammation that may involve any part of the DIGESTIVE TRACT from MOUTH to ANUS, mostly found in the ILEUM, the CECUM, and the COLON. In Crohn disease, the inflammation, extending through the intestinal wall from the MUCOSA to the serosa, is characteristically asymmetric and segmental. Epithelioid GRANULOMAS may be seen in some patients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients aged 6-18 years with colonic Crohn's disease or ulcerative colitis, who received standard therapy depending on the disease's severity, were randomized to receive 150 mg sodium butyrate twice a day (group A) or placebo (group B)." | 3.11 | Sodium Butyrate Effectiveness in Children and Adolescents with Newly Diagnosed Inflammatory Bowel Diseases-Randomized Placebo-Controlled Multicenter Trial. ( Banasiuk, M; Banaszkiewicz, A; Borys-Iwanicka, A; Pietrzak, A; Pytrus, T; Szczepanik, M; Walkowiak, J, 2022) |
| "34 individuals diagnosed with Crohn's disease participated in this study in 2011." | 1.39 | Faecalibacterium prausnitzii and Crohn's disease - is there any connection? ( Bartnicka, A; Eder, P; Gałecka, M; Schwiertz, A; Szachta, P; Łykowska-Szuber, L, 2013) |
| "Changes in ulcerative colitis were different from those in Crohn's disease (p = 0." | 1.29 | Colonic epithelium is diffusely abnormal in ulcerative colitis and colorectal cancer. ( Gibson, P; Nov, R; Rosella, O; Young, G, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (22.22) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (55.56) | 24.3611 |
| 2020's | 2 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Pietrzak, A | 1 |
| Banasiuk, M | 1 |
| Szczepanik, M | 1 |
| Borys-Iwanicka, A | 1 |
| Pytrus, T | 1 |
| Walkowiak, J | 1 |
| Banaszkiewicz, A | 1 |
| Handa, O | 1 |
| Miura, H | 1 |
| Gu, T | 1 |
| Osawa, M | 1 |
| Matsumoto, H | 1 |
| Umegaki, E | 1 |
| Inoue, R | 1 |
| Naito, Y | 1 |
| Shiotani, A | 1 |
| Kaden-Volynets, V | 1 |
| Günther, C | 1 |
| Zimmermann, J | 1 |
| Beisner, J | 1 |
| Becker, C | 1 |
| Bischoff, SC | 1 |
| Laserna-Mendieta, EJ | 1 |
| Clooney, AG | 1 |
| Carretero-Gomez, JF | 1 |
| Moran, C | 1 |
| Sheehan, D | 1 |
| Nolan, JA | 1 |
| Hill, C | 1 |
| Gahan, CGM | 1 |
| Joyce, SA | 1 |
| Shanahan, F | 1 |
| Claesson, MJ | 1 |
| Gałecka, M | 1 |
| Szachta, P | 1 |
| Bartnicka, A | 1 |
| Łykowska-Szuber, L | 1 |
| Eder, P | 1 |
| Schwiertz, A | 1 |
| Rieder, F | 1 |
| Karrasch, T | 1 |
| Ben-Horin, S | 1 |
| Schirbel, A | 1 |
| Ehehalt, R | 1 |
| Wehkamp, J | 1 |
| de Haar, C | 1 |
| Velin, D | 1 |
| Latella, G | 1 |
| Scaldaferri, F | 1 |
| Rogler, G | 1 |
| Higgins, P | 1 |
| Sans, M | 1 |
| Tjellström, B | 1 |
| Högberg, L | 1 |
| Stenhammar, L | 1 |
| Magnusson, KE | 1 |
| Midtvedt, T | 1 |
| Norin, E | 1 |
| Sundqvist, T | 1 |
| Gibson, P | 1 |
| Rosella, O | 1 |
| Nov, R | 1 |
| Young, G | 1 |
| Frankel, W | 1 |
| Lew, J | 1 |
| Su, B | 1 |
| Bain, A | 1 |
| Klurfeld, D | 1 |
| Einhorn, E | 1 |
| MacDermott, RP | 1 |
| Rombeau, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Identification of Predictive Biomarkers for Response to Biologic Therapies and Tofacitinib in Inflammatory Bowel Disease by Proteomic and Mass Cytometry Approaches[NCT03885713] | Phase 4 | 180 participants (Anticipated) | Interventional | 2019-09-10 | Recruiting | ||
| Washed Microbiota Transplantation Combining Exclusive Enteral Nutrition Contribute to Nutritional Improvement of Patients With Crohns' Disease[NCT02897661] | 30 participants (Anticipated) | Interventional | 2016-08-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for butyric acid and Crohn Disease
| Article | Year |
|---|---|
Results of the 2nd scientific workshop of the ECCO (III): basic mechanisms of intestinal healing.
Topics: Adrenal Cortex Hormones; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, | 2012 |
1 trial available for butyric acid and Crohn Disease
| Article | Year |
|---|---|
Sodium Butyrate Effectiveness in Children and Adolescents with Newly Diagnosed Inflammatory Bowel Diseases-Randomized Placebo-Controlled Multicenter Trial.
Topics: Adolescent; Butyric Acid; Child; Colitis, Ulcerative; Crohn Disease; Humans; Inflammatory Bowel Dise | 2022 |
7 other studies available for butyric acid and Crohn Disease
| Article | Year |
|---|---|
Reduction of butyric acid-producing bacteria in the ileal mucosa-associated microbiota is associated with the history of abdominal surgery in patients with Crohn's disease.
Topics: Bacteria; Butyric Acid; Crohn Disease; Gastrointestinal Microbiome; Humans; Ileum; Intestinal Mucosa | 2023 |
Deletion of the Casp8 gene in mice results in ileocolitis, gut barrier dysfunction, and malassimilation, which can be partially attenuated by inulin or sodium butyrate.
Topics: Animals; Body Weight; Butyric Acid; Caspase 8; Crohn Disease; Diet, Western; Dietary Supplements; Fe | 2019 |
Determinants of Reduced Genetic Capacity for Butyrate Synthesis by the Gut Microbiome in Crohn's Disease and Ulcerative Colitis.
Topics: Adult; Butyric Acid; Case-Control Studies; Clostridiales; Coenzyme A-Transferases; Colitis, Ulcerati | 2018 |
Faecalibacterium prausnitzii and Crohn's disease - is there any connection?
Topics: Butyric Acid; Crohn Disease; Gram-Positive Bacteria; Humans | 2013 |
Effect of exclusive enteral nutrition on gut microflora function in children with Crohn's disease.
Topics: Acetic Acid; Adolescent; Anus Diseases; Butyric Acid; Case-Control Studies; Child; Colitis; Crohn Di | 2012 |
Colonic epithelium is diffusely abnormal in ulcerative colitis and colorectal cancer.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Dif | 1995 |
Butyrate increases colonocyte protein synthesis in ulcerative colitis.
Topics: Aged; Butyrates; Butyric Acid; Cell Division; Cell Survival; Colitis, Ulcerative; Colon; Crohn Disea | 1994 |