butyric acid has been researched along with Colorectal Neoplasms in 49 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Butyric acid has been viewed with skepticism because of less convenient for long-term chronic therapy." | 6.40 | Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies. ( Pouillart, PR, 1998) |
| "We demonstrate that colorectal cancer cells utilize both a carnitine-dependent and carnitine-independent mechanism that contributes to butyrate oxidation." | 5.43 | Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells. ( Bennett, N; Donohoe, DR; Han, A; Johnstone, M; MacDonald, A; Whelan, J, 2016) |
| "Treatment with gefitinib resulted in the upregulation of p27Kip1 expression and induction of G1 cell cycle arrest, concomitantly associated with inactivation of PI3K/Akt signaling in COLM-5 cells and marked inhibition of xenografted tumors in nude mice, but not evident in COLM-2 cells." | 5.40 | Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity. ( Fujita, M; Hara, M; Ito, Y; Kanemitsu, Y; Kondo, E; Nakanishi, H; Nakata, S; Tanaka, H; Yatabe, Y, 2014) |
| " Here we demonstrate that histone deacetylase (HDAC) inhibitors (Trichostatin A, SAHA and sodium butyrate) promote TTP expression in colorectal cancer cells (HCA-7, HCT-116, Moser and SW480 cells) and cervix carcinoma cells (HeLa)." | 3.81 | Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells. ( Blanco, FF; Dixon, DA; Hu, L; Sanduja, S; Sobolewski, C, 2015) |
| " Because butyric acid (BA) is the major short-chain fatty acid produced by fermentation of dietary fiber in the large bowel, it may be an important regulator of apoptosis in colorectal cancer." | 3.71 | Butyric acid induces apoptosis by up-regulating Bax expression via stimulation of the c-Jun N-terminal kinase/activation protein-1 pathway in human colon cancer cells. ( Kumar, R; Mandal, M; Olson, DJ; Sharma, T; Vadlamudi, RK, 2001) |
| " Since butyric acid is the major short-chain fatty acid produced by fermentation of dietary fiber in the large bowel, it has been proposed that it could act as an important regulator of apoptosis in colorectal cancer." | 3.70 | Redistribution of activated caspase-3 to the nucleus during butyric acid-induced apoptosis. ( Adam, L; Kumar, R; Mandal, M, 1999) |
| "It has previously been observed that allyl isothiocyanate, a compound naturally present in the diet, is more cytotoxic toward the human colorectal adenocarcinoma cell line HT29 in its control transformed state than after exposure to sodium butyrate or to dimethylformamide, which slow growth and induce differentiation (detransformation)." | 3.69 | Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29. ( Fyfe, D; Johnson, IT; Musk, SR; Smith, TK; Stening, P; Stephenson, P, 1995) |
| "Epidemiological studies have linked dietary fiber to the prevention of human colorectal cancer and suggest that short chain fatty acids such as butyric acid, which is produced by fermentation of dietary fiber in the large intestine, may be an important mediator of the protective effects of fiber." | 3.69 | Bcl-2 deregulation leads to inhibition of sodium butyrate-induced apoptosis in human colorectal carcinoma cells. ( Kumar, R; Mandal, M; Wu, X, 1997) |
| "Butyric acid has been viewed with skepticism because of less convenient for long-term chronic therapy." | 2.40 | Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies. ( Pouillart, PR, 1998) |
| "We demonstrate that colorectal cancer cells utilize both a carnitine-dependent and carnitine-independent mechanism that contributes to butyrate oxidation." | 1.43 | Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells. ( Bennett, N; Donohoe, DR; Han, A; Johnstone, M; MacDonald, A; Whelan, J, 2016) |
| "Human colorectal cancer cell lines (HCT-116 and HT-29) were treated with sodium butyrate at concentrations ranging from 0." | 1.43 | Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis. ( Chen, J; Chen, S; Chu, X; Deng, H; Gong, M; Li, C; Li, Z; Mao, L; Sun, S; Yi, M; Zha, L; Zhang, J; Zhang, Z, 2016) |
| "Treatment with gefitinib resulted in the upregulation of p27Kip1 expression and induction of G1 cell cycle arrest, concomitantly associated with inactivation of PI3K/Akt signaling in COLM-5 cells and marked inhibition of xenografted tumors in nude mice, but not evident in COLM-2 cells." | 1.40 | Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity. ( Fujita, M; Hara, M; Ito, Y; Kanemitsu, Y; Kondo, E; Nakanishi, H; Nakata, S; Tanaka, H; Yatabe, Y, 2014) |
| "Changes in ulcerative colitis were different from those in Crohn's disease (p = 0." | 1.29 | Colonic epithelium is diffusely abnormal in ulcerative colitis and colorectal cancer. ( Gibson, P; Nov, R; Rosella, O; Young, G, 1995) |
| "Twenty patients resected for colorectal cancer were treated with 20 g/day of the fibre Plantago ovata seeds for 3 months, which increased the intake of fibre by 17." | 1.29 | Colonic production of butyrate in patients with previous colonic cancer during long-term treatment with dietary fibre (Plantago ovata seeds). ( Clausen, MR; Hove, H; Mortensen, PB; Nordgaard, I, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (2.04) | 18.7374 |
| 1990's | 22 (44.90) | 18.2507 |
| 2000's | 5 (10.20) | 29.6817 |
| 2010's | 13 (26.53) | 24.3611 |
| 2020's | 8 (16.33) | 2.80 |
| Authors | Studies |
|---|---|
| Li, F | 1 |
| Wu, Y | 1 |
| Yan, Y | 1 |
| Wu, S | 1 |
| Zhu, J | 2 |
| Zhang, G | 1 |
| Zhang, P | 1 |
| Yuan, L | 1 |
| Zeng, Y | 1 |
| Liu, Z | 1 |
| Kaźmierczak-Siedlecka, K | 3 |
| Marano, L | 3 |
| Merola, E | 3 |
| Roviello, F | 3 |
| Połom, K | 3 |
| Cacciola, NA | 1 |
| Venneri, T | 1 |
| Salzano, A | 1 |
| D'Onofrio, N | 1 |
| Martano, M | 1 |
| Saggese, A | 1 |
| Vinale, F | 1 |
| Neglia, G | 1 |
| Campanile, C | 1 |
| Baccigalupi, L | 1 |
| Maiolino, P | 1 |
| Cuozzo, M | 1 |
| Russo, R | 1 |
| Balestrieri, ML | 1 |
| D'Occhio, MJ | 1 |
| Ricca, E | 1 |
| Borrelli, F | 1 |
| Campanile, G | 1 |
| Ma, X | 1 |
| Zhou, Z | 1 |
| Zhang, X | 1 |
| Fan, M | 1 |
| Hong, Y | 1 |
| Feng, Y | 1 |
| Dong, Q | 2 |
| Diao, H | 1 |
| Wang, G | 2 |
| Xi, Y | 1 |
| Jing, Z | 1 |
| Wei, W | 1 |
| Chun, Z | 1 |
| Quan, Q | 1 |
| Qing, Z | 1 |
| Jiamin, X | 1 |
| Shuwen, H | 1 |
| Wang, S | 1 |
| Fan, X | 1 |
| Xu, D | 1 |
| Li, R | 1 |
| Chen, R | 1 |
| Hu, J | 1 |
| Shen, Y | 1 |
| Hao, J | 1 |
| Wang, K | 1 |
| Jiang, X | 1 |
| Wang, Y | 1 |
| Jiang, Y | 1 |
| Li, J | 1 |
| Zhang, J | 2 |
| Baldi, S | 1 |
| Menicatti, M | 1 |
| Nannini, G | 1 |
| Niccolai, E | 1 |
| Russo, E | 1 |
| Ricci, F | 1 |
| Pallecchi, M | 1 |
| Romano, F | 1 |
| Pedone, M | 1 |
| Poli, G | 1 |
| Renzi, D | 1 |
| Taddei, A | 1 |
| Calabrò, AS | 1 |
| Stingo, FC | 1 |
| Bartolucci, G | 1 |
| Amedei, A | 1 |
| Stokowa-Sołtys, K | 1 |
| Wojtkowiak, K | 1 |
| Jagiełło, K | 1 |
| Tortora, K | 1 |
| Femia, AP | 1 |
| Romagnoli, A | 1 |
| Sineo, I | 1 |
| Khatib, M | 1 |
| Mulinacci, N | 1 |
| Giovannelli, L | 1 |
| Caderni, G | 1 |
| Anantharaju, PG | 1 |
| Reddy, DB | 1 |
| Padukudru, MA | 1 |
| Chitturi, CMK | 1 |
| Vimalambike, MG | 1 |
| Madhunapantula, SV | 1 |
| Xu, Z | 1 |
| Tao, J | 1 |
| Chen, P | 1 |
| Chen, L | 1 |
| Sharma, S | 1 |
| Zhou, Q | 1 |
| Li, G | 1 |
| Zuo, S | 1 |
| Zhu, W | 1 |
| Yuan, X | 1 |
| Rawłuszko, AA | 1 |
| Antoniucci, M | 1 |
| Horbacka, K | 2 |
| Lianeri, M | 1 |
| Krokowicz, P | 2 |
| Jagodziński, PP | 2 |
| Nakata, S | 1 |
| Tanaka, H | 1 |
| Ito, Y | 1 |
| Hara, M | 1 |
| Fujita, M | 1 |
| Kondo, E | 1 |
| Kanemitsu, Y | 1 |
| Yatabe, Y | 1 |
| Nakanishi, H | 1 |
| Sobolewski, C | 1 |
| Sanduja, S | 1 |
| Blanco, FF | 1 |
| Hu, L | 1 |
| Dixon, DA | 1 |
| Rawłuszko-Wieczorek, AA | 1 |
| Horst, N | 1 |
| Bandura, AS | 1 |
| Świderska, M | 1 |
| Han, A | 2 |
| Bennett, N | 2 |
| MacDonald, A | 1 |
| Johnstone, M | 2 |
| Whelan, J | 2 |
| Donohoe, DR | 2 |
| Yi, M | 1 |
| Zha, L | 1 |
| Chen, S | 1 |
| Li, Z | 1 |
| Li, C | 1 |
| Gong, M | 1 |
| Deng, H | 1 |
| Chu, X | 1 |
| Chen, J | 1 |
| Zhang, Z | 1 |
| Mao, L | 1 |
| Sun, S | 1 |
| Kapuvári, B | 1 |
| Hegedüs, R | 1 |
| Schulcz, Á | 1 |
| Manea, M | 1 |
| Tóvári, J | 1 |
| Gacs, A | 1 |
| Vincze, B | 1 |
| Mező, G | 1 |
| Standifer, C | 1 |
| Smith, A | 1 |
| Bettaieb, A | 1 |
| Humphreys, KJ | 1 |
| Cobiac, L | 1 |
| Le Leu, RK | 1 |
| Van der Hoek, MB | 1 |
| Michael, MZ | 1 |
| Serpe, L | 1 |
| Catalano, MG | 1 |
| Cavalli, R | 1 |
| Ugazio, E | 1 |
| Bosco, O | 1 |
| Canaparo, R | 1 |
| Muntoni, E | 1 |
| Frairia, R | 1 |
| Gasco, MR | 1 |
| Eandi, M | 1 |
| Zara, GP | 1 |
| Schwab, M | 1 |
| Reynders, V | 1 |
| Ulrich, S | 1 |
| Zahn, N | 1 |
| Stein, J | 2 |
| Schröder, O | 1 |
| Gibson, P | 1 |
| Rosella, O | 1 |
| Nov, R | 1 |
| Young, G | 1 |
| Higgins, PJ | 1 |
| Lipkin, M | 1 |
| Hague, A | 2 |
| Manning, AM | 1 |
| van der Stappen, JW | 1 |
| Paraskeva, C | 2 |
| Musk, SR | 1 |
| Stephenson, P | 1 |
| Smith, TK | 1 |
| Stening, P | 1 |
| Fyfe, D | 1 |
| Johnson, IT | 1 |
| Velázquez, OC | 1 |
| Jabbar, A | 1 |
| DeMatteo, RP | 1 |
| Rombeau, JL | 1 |
| Nordgaard, I | 1 |
| Hove, H | 1 |
| Clausen, MR | 1 |
| Mortensen, PB | 1 |
| Mandal, M | 4 |
| Wu, X | 1 |
| Kumar, R | 4 |
| Bingham, S | 1 |
| Diaz, GD | 1 |
| Hicks, DJ | 1 |
| Krajewski, S | 1 |
| Reed, JC | 1 |
| Sovová, V | 1 |
| Sloncová, E | 1 |
| Fric, P | 1 |
| von Engelhardt, W | 1 |
| Bartels, J | 1 |
| Kirschberger, S | 1 |
| Meyer zu Düttingdorf, HD | 1 |
| Busche, R | 1 |
| Nakano, K | 1 |
| Yamagishi, H | 1 |
| Oka, T | 1 |
| Sakai, T | 1 |
| Kamitani, H | 1 |
| Geller, M | 1 |
| Eling, T | 1 |
| Adam, L | 2 |
| Mendelsohn, J | 1 |
| Pouillart, PR | 1 |
| Maclean, KN | 1 |
| McKay, IA | 1 |
| Bustin, SA | 1 |
| Wächtershäuser, A | 1 |
| Steinhilber, D | 1 |
| Loitsch, SM | 1 |
| Olson, DJ | 1 |
| Sharma, T | 1 |
| Vadlamudi, RK | 1 |
| Nancey, S | 1 |
| Coffin, B | 1 |
| Descos, L | 1 |
| Flourié, B | 1 |
| Hay, FG | 1 |
| Duncan, LW | 1 |
| Langdon, SP | 1 |
| Leonard, RC | 1 |
| Nakai, T | 1 |
| Endo, K | 1 |
| Hosono, M | 1 |
| Saga, T | 1 |
| Watanabe, Y | 1 |
| Sakahara, H | 1 |
| Imai, K | 1 |
| Yachi, A | 1 |
| Kiyozuka, Y | 1 |
| Ishiwata, I | 1 |
| Lee, MJ | 1 |
| Latella, G | 1 |
| Caprilli, R | 1 |
| Saini, K | 1 |
| Steele, G | 1 |
| Thomas, P | 1 |
| Bägli, DJ | 1 |
| Steele, GD | 1 |
| Barlozzari, T | 1 |
8 reviews available for butyric acid and Colorectal Neoplasms
| Article | Year |
|---|---|
Sodium butyrate in both prevention and supportive treatment of colorectal cancer.
Topics: Butyric Acid; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Micr | 2022 |
Sodium butyrate in both prevention and supportive treatment of colorectal cancer.
Topics: Butyric Acid; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Micr | 2022 |
Sodium butyrate in both prevention and supportive treatment of colorectal cancer.
Topics: Butyric Acid; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Micr | 2022 |
Sodium butyrate in both prevention and supportive treatment of colorectal cancer.
Topics: Butyric Acid; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Micr | 2022 |
Sodium butyrate in both prevention and supportive treatment of colorectal cancer.
Topics: Butyric Acid; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Micr | 2022 |
Sodium butyrate in both prevention and supportive treatment of colorectal cancer.
Topics: Butyric Acid; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Micr | 2022 |
Sodium butyrate in both prevention and supportive treatment of colorectal cancer.
Topics: Butyric Acid; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Micr | 2022 |
Sodium butyrate in both prevention and supportive treatment of colorectal cancer.
Topics: Butyric Acid; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Micr | 2022 |
Sodium butyrate in both prevention and supportive treatment of colorectal cancer.
Topics: Butyric Acid; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Micr | 2022 |
Fusobacterium nucleatum - Friend or foe?
Topics: Animals; Butyric Acid; Colon; Colorectal Neoplasms; Female; Fusobacterium Infections; Fusobacterium | 2021 |
Escape from negative regulation of growth by transforming growth factor beta and from the induction of apoptosis by the dietary agent sodium butyrate may be important in colorectal carcinogenesis.
Topics: Apoptosis; Butyrates; Butyric Acid; Cell Division; Colorectal Neoplasms; Dietary Fiber; Growth Subst | 1993 |
Meat, starch and non-starch polysaccharides, are epidemiological and experimental findings consistent with acquired genetic alterations in sporadic colorectal cancer?
Topics: Animals; Bile Acids and Salts; Butyrates; Butyric Acid; Colorectal Neoplasms; Diet; Female; Fermenta | 1997 |
Role of short-chain fatty acids in the hind gut.
Topics: Animals; Apoptosis; Butyrates; Butyric Acid; Cell Division; Colitis; Colon; Colorectal Neoplasms; Di | 1998 |
[A novel approach for cancer chemoprevention referred to as "gene-regulating chemoprevention"].
Topics: Butyrates; Butyric Acid; Cell Cycle; Colorectal Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cy | 1998 |
Role of butyric acid and its derivatives in the treatment of colorectal cancer and hemoglobinopathies.
Topics: Animals; Antineoplastic Agents; Butyric Acid; Colorectal Neoplasms; Hemoglobinopathies; Humans; Prod | 1998 |
Metabolism of large bowel mucosa in health and disease.
Topics: Anaerobiosis; Butyrates; Butyric Acid; Colitis; Colitis, Ulcerative; Colon; Colorectal Neoplasms; Di | 1991 |
41 other studies available for butyric acid and Colorectal Neoplasms
| Article | Year |
|---|---|
Transcriptomic landscape of sodium butyrate-induced growth inhibition of human colorectal cancer organoids.
Topics: Butyric Acid; Colorectal Neoplasms; Dietary Fiber; Humans; Integrins; Organoids; Phosphatidylinosito | 2022 |
Chemopreventive effect of a milk whey by-product derived from Buffalo (Bubalus bubalis) in protecting from colorectal carcinogenesis.
Topics: Animals; Azoxymethane; Buffaloes; Butyric Acid; Carcinogenesis; Colorectal Neoplasms; Humans; Mice; | 2023 |
Sodium butyrate modulates gut microbiota and immune response in colorectal cancer liver metastatic mice.
Topics: Animals; Butyric Acid; Cell Line, Tumor; Colorectal Neoplasms; Gastrointestinal Microbiome; Immunity | 2020 |
Inhibitory effect of sodium butyrate on colorectal cancer cells and construction of the related molecular network.
Topics: Apoptosis; Butyric Acid; Cell Cycle; Cell Line, Tumor; Cell Movement; Cell Proliferation; Colorectal | 2021 |
The differentiation of colorectal cancer is closely relevant to m6A modification.
Topics: Adenosine; Butyric Acid; Cell Cycle Proteins; Cell Differentiation; Cell Line, Tumor; Colorectal Neo | 2021 |
Free Fatty Acids Signature in Human Intestinal Disorders: Significant Association between Butyric Acid and Celiac Disease.
Topics: Adenomatous Polyposis Coli; Adult; Age Factors; Aged; Aged, 80 and over; Biomarkers; Body Mass Index | 2021 |
Pomegranate By-Products in Colorectal Cancer Chemoprevention: Effects in Apc-Mutated Pirc Rats and Mechanistic Studies In Vitro and Ex Vivo.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Anticarcinogenic Agents; Apoptosis; Butyric Ac | 2018 |
Induction of colon and cervical cancer cell death by cinnamic acid derivatives is mediated through the inhibition of Histone Deacetylases (HDAC).
Topics: Apoptosis; Binding Sites; Butyric Acid; Cell Line, Tumor; Cinnamates; Colorectal Neoplasms; Female; | 2017 |
Sodium Butyrate Inhibits Colorectal Cancer Cell Migration by Downregulating Bmi-1 Through Enhanced miR-200c Expression.
Topics: Animals; Apoptosis; Butyric Acid; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Colorec | 2018 |
RNA Sequencing Analysis of Molecular Basis of Sodium Butyrate-Induced Growth Inhibition on Colorectal Cancer Cell Lines.
Topics: Apoptosis; Butyric Acid; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colorectal Ne | 2019 |
Reduced expression of steroid sulfatase in primary colorectal cancer.
Topics: Adenocarcinoma; Aged; Butyric Acid; Cell Line, Tumor; Colon; Colorectal Neoplasms; Female; Humans; I | 2013 |
Deficient HER3 expression in poorly-differentiated colorectal cancer cells enhances gefitinib sensitivity.
Topics: Animals; Antineoplastic Agents; Butyric Acid; Cell Cycle; Cell Differentiation; Cell Line, Tumor; Co | 2014 |
Histone Deacetylase Inhibitors Activate Tristetraprolin Expression through Induction of Early Growth Response Protein 1 (EGR1) in Colorectal Cancer Cells.
Topics: Butyric Acid; Cell Line, Tumor; Colorectal Neoplasms; Cyclooxygenase 2; Early Growth Response Protei | 2015 |
Effect of DNA methylation profile on OATP3A1 and OATP4A1 transcript levels in colorectal cancer.
Topics: Aged; Azacitidine; Butyric Acid; Caco-2 Cells; Colorectal Neoplasms; Decitabine; DNA Methylation; Do | 2015 |
Cellular Metabolism and Dose Reveal Carnitine-Dependent and -Independent Mechanisms of Butyrate Oxidation in Colorectal Cancer Cells.
Topics: Acetylation; Antineoplastic Agents; Butyric Acid; Carnitine; Carnitine O-Palmitoyltransferase; Color | 2016 |
Sodium Butyrate Induces Endoplasmic Reticulum Stress and Autophagy in Colorectal Cells: Implications for Apoptosis.
Topics: Adenocarcinoma; Apoptosis; Autophagy; Blotting, Western; Butyric Acid; Cell Proliferation; Colorecta | 2016 |
Improved in vivo antitumor effect of a daunorubicin - GnRH-III bioconjugate modified by apoptosis inducing agent butyric acid on colorectal carcinoma bearing mice.
Topics: Animals; Antibiotics, Antineoplastic; Butyric Acid; Cell Proliferation; Colorectal Neoplasms; Daunor | 2016 |
Characterization of the Pro-Inflammatory Cytokine IL-1β on Butyrate Oxidation in Colorectal Cancer Cells.
Topics: Butyric Acid; Colorectal Neoplasms; Energy Metabolism; Glucose; HCT116 Cells; Humans; Interleukin-1b | 2017 |
Histone deacetylase inhibition in colorectal cancer cells reveals competing roles for members of the oncogenic miR-17-92 cluster.
Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Apoptosis Regulatory Proteins; Bcl-2-Like Prot | 2013 |
Cytotoxicity of anticancer drugs incorporated in solid lipid nanoparticles on HT-29 colorectal cancer cell line.
Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Butyric Acid; Cell Survival; | 2004 |
PPARgamma is a key target of butyrate-induced caspase-3 activation in the colorectal cancer cell line Caco-2.
Topics: Butyric Acid; Caco-2 Cells; Caspase 3; Caspase 8; Caspase 9; Colorectal Neoplasms; Enzyme Activation | 2006 |
Colonic epithelium is diffusely abnormal in ulcerative colitis and colorectal cancer.
Topics: Adult; Age Factors; Aged; Aged, 80 and over; Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Dif | 1995 |
Expression of plasminogen activator inhibitor type 1 (PAI-1) by HT-29di human large bowel carcinoma cells is modulated as a function of epithelial differentiation.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Adhesion; Cell Count; Cell Differentiation; Colo | 1994 |
Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29.
Topics: Adenocarcinoma; Allyl Compounds; Anticarcinogenic Agents; Butyrates; Butyric Acid; Cell Differentiat | 1995 |
Butyrate inhibits seeding and growth of colorectal metastases to the liver in mice.
Topics: Animals; Butyrates; Butyric Acid; Cell Division; Colorectal Neoplasms; Liver Neoplasms; Mevalonic Ac | 1996 |
Colonic production of butyrate in patients with previous colonic cancer during long-term treatment with dietary fibre (Plantago ovata seeds).
Topics: Aged; Aged, 80 and over; Analysis of Variance; Butyrates; Butyric Acid; Colorectal Neoplasms; Dietar | 1996 |
Bcl-2 deregulation leads to inhibition of sodium butyrate-induced apoptosis in human colorectal carcinoma cells.
Topics: Apoptosis; Butyrates; Butyric Acid; Cell Survival; Colorectal Neoplasms; DNA Fragmentation; Down-Reg | 1997 |
bcl-2 and bak may play a pivotal role in sodium butyrate-induced apoptosis in colonic epithelial cells; however overexpression of bcl-2 does not protect against bak-mediated apoptosis.
Topics: Adenoma; Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Butyrate | 1997 |
Differences of alkaline phosphatase and arginase activities in human colorectal carcinoma cell lines.
Topics: Alkaline Phosphatase; Arginase; Butyrates; Butyric Acid; Carcinoma; Cell Differentiation; Colorectal | 1997 |
Expression of 15-lipoxygenase by human colorectal carcinoma Caco-2 cells during apoptosis and cell differentiation.
Topics: Apoptosis; Arachidonate 15-Lipoxygenase; Butyrates; Butyric Acid; Caco-2 Cells; Cell Differentiation | 1998 |
Nuclear targeting of Bax during apoptosis in human colorectal cancer cells.
Topics: Antibodies, Monoclonal; Apoptosis; bcl-2-Associated X Protein; Biological Transport; Butyrates; Buty | 1998 |
Differential effects of sodium butyrate on the transcription of the human TIS11 family of early-response genes in colorectal cancer cells.
Topics: Butyrate Response Factor 1; Butyric Acid; Colorectal Neoplasms; DNA-Binding Proteins; Gene Expressio | 1998 |
Redistribution of activated caspase-3 to the nucleus during butyric acid-induced apoptosis.
Topics: Apoptosis; Butyric Acid; Caspase 3; Caspase Inhibitors; Caspases; Catalytic Domain; Cell Nucleus; Co | 1999 |
Expression of 5-lipoxygenase by human colorectal carcinoma Caco-2 cells during butyrate-induced cell differentiation.
Topics: 5-Lipoxygenase-Activating Proteins; Arachidonate 5-Lipoxygenase; Butyric Acid; Caco-2 Cells; Carrier | 2000 |
Butyric acid induces apoptosis by up-regulating Bax expression via stimulation of the c-Jun N-terminal kinase/activation protein-1 pathway in human colon cancer cells.
Topics: Apoptosis; bcl-2-Associated X Protein; Butyric Acid; Colorectal Neoplasms; DNA Fragmentation; Gene E | 2001 |
[Colonic microflora and cancer].
Topics: Adenoma; Animals; Bacteria; Bile Acids and Salts; Butyric Acid; Carcinogens; Colon; Colonic Neoplasm | 2001 |
Modulation of the cluster 1 and mucin antigens in human small cell lung cancer and other epithelial tumour cell lines after treatment with the differentiation inducing agent, sodium butyrate.
Topics: Adenocarcinoma; Alkaline Phosphatase; Antibodies, Monoclonal; Antigens, Neoplasm; Butyrates; Butyric | 1991 |
Drug effects on CA125 antigen expression and antibody binding to cancer cells.
Topics: Antibodies, Monoclonal; Antigens, Tumor-Associated, Carbohydrate; Binding Sites, Antibody; Bucladesi | 1991 |
Relationship between stool pH and butyrate levels.
Topics: Butyrates; Butyric Acid; Colorectal Neoplasms; Feces; Humans; Hydrogen-Ion Concentration; Risk Facto | 1991 |
Induction of carcinoembryonic-antigen-gene expression in human colorectal carcinoma by sodium butyrate.
Topics: Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Differentiation; Cell Line; Cell Nucleus; Cl | 1990 |
Natural killer sensitivity of colorectal carcinoma targets. Correlation with degree of differentiation.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Colorectal Neoplasms; Cytotoxicity, Immuno | 1989 |