butyric acid has been researched along with Colonic Neoplasms in 145 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Colonic Neoplasms: Tumors or cancer of the COLON.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The aim of the present study was to elucidate the probable mechanisms involved in the beneficial effects of a fiber-supplemented diet (5% Plantago ovata seeds) in the trinitrobenzenesulfonic acid (TNBS) model of rat colitis, with special attention to its effects on the production of some of the mediators involved in the inflammatory response, such as tumor necrosis factor alpha (TNFalpha) and nitric oxide (NO)." | 3.71 | Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats. ( Azzouz, S; Camuesco, D; Concha, A; Gálvez, J; Lorente, MD; Osuna, A; Redondo, L; Rodríguez-Cabezas, ME; Zarzuelo, A, 2002) |
| "Butyrate induces differentiation of colon cancer cell lines." | 2.39 | Butyrate and the colonocyte. Implications for neoplasia. ( Lederer, HM; Rombeau, JL; Velázquez, OC, 1996) |
| "Butyric acid (BA) is a kind of HDAC inhibitor and thus shows tumor suppression to colon cancer." | 1.62 | A novel dual-prodrug carried by cyclodextrin inclusion complex for the targeting treatment of colon cancer. ( Bai, X; Chen, L; Lin, Y; Liu, Z; Luo, Z; Yang, R; Zhang, Z; Zhong, Z; Zhou, M, 2021) |
| "Screening of a panel of 33 colon cancer cell lines identified cell lines sensitive (42%) and resistant (58%) to butyrate induction of ALP activity." | 1.40 | The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner. ( Ahmed, N; Al-Obaidi, S; Arango, D; Augenlicht, LH; Buchanan, DD; Carr, A; Chionh, F; Chueh, AC; Corner, GA; Dávalos-Salas, M; Dávaos-Salas, M; Dhillon, AS; Hodin, RA; Malo, MS; Mariadason, JM; Shin, J; Sieber, OM; Tögel, L; Tran, H; Weber, TK; Young, JP, 2014) |
| "Tumorigenesis was not affected by CD166 expression." | 1.39 | CD49f-positive cell population efficiently enriches colon cancer-initiating cells. ( Doki, Y; Haraguchi, N; Hata, T; Ishii, H; Mimori, K; Mizushima, T; Mori, M; Nishimura, J; Ohta, K; Takemasa, I; Uemura, M; Yamamoto, H, 2013) |
| "In this study we used colon cancer cell lines to study the cellular and molecular events that take place during co-treatment with NaB, EC and EGCG." | 1.39 | Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1. ( Cascante, M; Centelles, JJ; Dudeja, PK; Sánchez-Tena, S; Vizán, P, 2013) |
| "The differentiation of colon cancer cell lines is associated with changes in calcium homeostasis." | 1.34 | Plasma membrane Ca2+-ATPase expression during colon cancer cell line differentiation. ( Aung, CS; Kruger, WA; Monteith, GR; Poronnik, P; Roberts-Thomson, SJ, 2007) |
| "Thus, we have tested polyposis coli Pc/AA adenoma cells, Caco-2, HT-29 and LS174T adenocarcinoma cell lines." | 1.31 | Deregulated expression of homeobox-containing genes, HOXB6, B8, C8, C9, and Cdx-1, in human colon cancer cell lines. ( Chastre, E; Gazit, A; Gespach, C; Halperin, M; Mashiah, P; Vider, BZ; Yaniv, A; Zimber, A, 2000) |
| "Three colonic cancer cell lines (HT-29, Caco-2, and T84 cells) were studied." | 1.31 | Sodium butyrate enhances complement-mediated cell injury via down-regulation of decay-accelerating factor expression in colonic cancer cells. ( Andoh, A; Araki, Y; Bamba, T; Fujiyama, Y; Shimada, M, 2002) |
| "n-Butyrate inhibits the growth of colon cancer cell lines." | 1.30 | Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors. ( Eastman, A; McBain, JA; Mueller, GC; Nobel, CS, 1997) |
| "We show here that human and rat colon cancer cells undergo massive apoptosis when they are exposed to soluble Fas ligand in the presence of sodium butyrate, an agent that induces by itself only a low rate of apoptosis." | 1.30 | Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate. ( Bonnotte, B; Chauffert, B; Droin, N; Favre, N; Fontana, A; Garrido, C; Martin, F; Micheau, O; Reveneau, S; Solary, E, 1998) |
| "We have chosen two human colon cancer cell lines that differ in their ability to metabolize long-chain fatty acids (LCFAs), LS174T cells and HT-29 cells." | 1.29 | Prostaglandin synthesis in human cancer cells: influence of fatty acids and butyrate. ( Awad, AB; Fink, CS; Horvath, PJ; Kamei, A, 1995) |
| "Vaccination of patients with colon cancer with irradiated autologous tumor cells and bacille Calmette-Guérin (BCG) was reported to augment mean survival." | 1.29 | Immunization against a rat colon carcinoma by sodium butyrate-treated cells but not by interleukin 2-secreting cells. ( Douillard, JY; Le Pendu, J; Meflah, K; Patry, Y, 1995) |
| "3." | 1.29 | n-Butyrate mediation of ganglioside expression of human and murine cancer cells demonstrates relative cell specificity. ( Berenson, CS; Lance, P; Miqdadi, JA; Patterson, MA, 1995) |
| "Allyl isothiocyanate was also found to be less cytostatic to the mass growth of detransformed populations in that daily doses of 1." | 1.29 | Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29. ( Johnson, IT; Musk, SR, 1993) |
| "The human colon cancer cell line SW-620 produces two alkaline phosphatases (ALPs) which are not expressed by normal colon." | 1.29 | Divergent effects of butyrate on the alkaline phosphatases of SW-620 cells. ( Herz, F, 1993) |
| "Other colon cancer cell lines were examined for the extent of cell death following treatment with TPA/butyrate." | 1.29 | Phorbol ester augments butyrate-induced apoptosis of colon cancer cells. ( Eastman, A; McBain, JA; Mueller, GC; Pettit, GR; Simmons, DL, 1996) |
| "The PLAP promoters from four colon cancer cell lines with widely varied butyrate-inducible alkaline phosphatase activity were thermally amplified and sequenced." | 1.28 | Transcriptional regulation of the human placental-like alkaline phosphatase gene and mechanisms involved in its induction by sodium butyrate. ( Deng, G; Gum, JR; Hu, L; Kim, YS; Liu, G, 1992) |
| "The human colonic cancer cell line HT29 is undifferentiated in standard culture conditions (Dulbecco's medium:10% fetal bovine serum)." | 1.27 | Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate. ( Augeron, C; Laboisse, CL, 1984) |
| "All three colon cancer cell lines regardless of their state of differentiation had their growth markedly slowed by sodium butyrate, and to a lesser extent by retinoic acid." | 1.27 | The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation. ( Niles, RM; Thomas, P; Wilhelm, SA; Zamcheck, N, 1988) |
| "Clone A human colon cancer cells were exposed to concentrations of sodium butyrate (NAB, 0-2 mM) for three passages in vitro, and responses to either graded single doses or split doses of 250 kVp X rays were determined." | 1.27 | Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate. ( Arundel, CM; Bliven, SF; Hallows, KT; Leith, JT, 1988) |
| "Although previous in vitro reports on colon cancer cell lines have suggested that sodium butyrate might have a role to play as a chemotherapeutic "differentiating agent," the results of this in vivo study indicate that sodium butyrate treatment enhanced the development of colonic neoplasia and was associated with increased fecal butyric acid concentrations." | 1.27 | Effects of differing concentrations of sodium butyrate on 1,2-dimethylhydrazine-induced rat intestinal neoplasia. ( Freeman, HJ, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (20.00) | 18.7374 |
| 1990's | 76 (52.41) | 18.2507 |
| 2000's | 17 (11.72) | 29.6817 |
| 2010's | 14 (9.66) | 24.3611 |
| 2020's | 9 (6.21) | 2.80 |
| Authors | Studies |
|---|---|
| Vale, N | 1 |
| Correia-Branco, A | 1 |
| Patrício, B | 1 |
| Duarte, D | 1 |
| Martel, F | 1 |
| Chen, L | 1 |
| Lin, Y | 1 |
| Zhang, Z | 1 |
| Yang, R | 1 |
| Bai, X | 1 |
| Liu, Z | 1 |
| Luo, Z | 1 |
| Zhou, M | 1 |
| Zhong, Z | 1 |
| Chen, YS | 1 |
| Li, J | 1 |
| Neja, S | 1 |
| Kapoor, S | 1 |
| Tovar Perez, JE | 1 |
| Tripathi, C | 1 |
| Menon, R | 1 |
| Jayaraman, A | 1 |
| Lee, K | 1 |
| Dashwood, WM | 1 |
| Wang, S | 1 |
| Zhang, K | 1 |
| Kobayashi, K | 1 |
| Rajendran, P | 1 |
| Dashwood, R | 1 |
| Botta, C | 1 |
| Spyridopoulou, K | 1 |
| Bertolino, M | 1 |
| Rantsiou, K | 1 |
| Chlichlia, K | 1 |
| Cocolin, L | 1 |
| Sanaei, M | 1 |
| Kavoosi, F | 1 |
| Wang, L | 1 |
| Shannar, AAF | 1 |
| Wu, R | 1 |
| Chou, P | 1 |
| Sarwar, MS | 1 |
| Kuo, HC | 1 |
| Peter, RM | 1 |
| Wang, Y | 2 |
| Su, X | 1 |
| Kong, AN | 1 |
| Park, M | 1 |
| Kwon, J | 1 |
| Shin, HJ | 1 |
| Moon, SM | 1 |
| Kim, SB | 1 |
| Shin, US | 1 |
| Han, YH | 1 |
| Kim, Y | 1 |
| Cambria, MT | 1 |
| Villaggio, G | 1 |
| Laudani, S | 1 |
| Pulvirenti, L | 1 |
| Federico, C | 1 |
| Saccone, S | 1 |
| Condorelli, GG | 1 |
| Sinatra, F | 1 |
| Klepinina, L | 1 |
| Klepinin, A | 1 |
| Truu, L | 1 |
| Chekulayev, V | 1 |
| Vija, H | 1 |
| Kuus, K | 1 |
| Teino, I | 1 |
| Pook, M | 1 |
| Maimets, T | 1 |
| Kaambre, T | 1 |
| Giuliano, M | 1 |
| Pellerito, C | 1 |
| Celesia, A | 1 |
| Fiore, T | 1 |
| Emanuele, S | 1 |
| Lucchetti, D | 1 |
| Calapà, F | 1 |
| Palmieri, V | 1 |
| Fanali, C | 1 |
| Carbone, F | 1 |
| Papa, A | 1 |
| De Maria, R | 1 |
| De Spirito, M | 1 |
| Sgambato, A | 1 |
| Tortora, K | 1 |
| Femia, AP | 1 |
| Romagnoli, A | 1 |
| Sineo, I | 1 |
| Khatib, M | 1 |
| Mulinacci, N | 1 |
| Giovannelli, L | 1 |
| Caderni, G | 2 |
| Yin, DT | 1 |
| Fu, Y | 1 |
| Zhao, XH | 1 |
| Sonoda, A | 1 |
| Kamiyama, N | 1 |
| Ozaka, S | 1 |
| Gendo, Y | 1 |
| Ozaki, T | 1 |
| Hirose, H | 1 |
| Noguchi, K | 1 |
| Saechue, B | 1 |
| Sachi, N | 1 |
| Sakai, K | 1 |
| Mizukami, K | 1 |
| Hidano, S | 1 |
| Murakami, K | 1 |
| Kobayashi, T | 1 |
| Haraguchi, N | 1 |
| Ishii, H | 1 |
| Mimori, K | 1 |
| Ohta, K | 1 |
| Uemura, M | 1 |
| Nishimura, J | 1 |
| Hata, T | 1 |
| Takemasa, I | 1 |
| Mizushima, T | 1 |
| Yamamoto, H | 1 |
| Doki, Y | 1 |
| Mori, M | 1 |
| Sánchez-Tena, S | 1 |
| Vizán, P | 1 |
| Dudeja, PK | 2 |
| Centelles, JJ | 1 |
| Cascante, M | 1 |
| Saldanha, SN | 1 |
| Kala, R | 1 |
| Tollefsbol, TO | 1 |
| Shin, J | 1 |
| Carr, A | 1 |
| Corner, GA | 1 |
| Tögel, L | 1 |
| Dávalos-Salas, M | 1 |
| Dávaos-Salas, M | 1 |
| Tran, H | 1 |
| Chueh, AC | 1 |
| Al-Obaidi, S | 1 |
| Chionh, F | 1 |
| Ahmed, N | 1 |
| Buchanan, DD | 1 |
| Young, JP | 1 |
| Malo, MS | 1 |
| Hodin, RA | 2 |
| Arango, D | 1 |
| Sieber, OM | 1 |
| Augenlicht, LH | 2 |
| Dhillon, AS | 1 |
| Weber, TK | 1 |
| Mariadason, JM | 1 |
| Katzenmaier, EM | 1 |
| André, S | 1 |
| Kopitz, J | 1 |
| Gabius, HJ | 1 |
| Gurav, A | 1 |
| Sivaprakasam, S | 1 |
| Bhutia, YD | 1 |
| Boettger, T | 1 |
| Singh, N | 1 |
| Ganapathy, V | 1 |
| Lazarova, DL | 1 |
| Bordonaro, M | 2 |
| Tylichová, Z | 1 |
| Straková, N | 1 |
| Vondráček, J | 1 |
| Vaculová, AH | 1 |
| Kozubík, A | 1 |
| Hofmanová, J | 2 |
| R, M | 1 |
| P, HA | 1 |
| Mahadevan, V | 1 |
| Rodríguez-Cabezas, ME | 1 |
| Gálvez, J | 2 |
| Lorente, MD | 1 |
| Concha, A | 1 |
| Camuesco, D | 1 |
| Azzouz, S | 1 |
| Osuna, A | 1 |
| Redondo, L | 1 |
| Zarzuelo, A | 2 |
| McMillan, L | 1 |
| Butcher, SK | 1 |
| Pongracz, J | 1 |
| Lord, JM | 1 |
| Collard, TJ | 1 |
| Guy, M | 1 |
| Butt, AJ | 1 |
| Perks, CM | 1 |
| Holly, JM | 1 |
| Paraskeva, C | 7 |
| Williams, AC | 3 |
| Alrefai, WA | 1 |
| Tyagi, S | 1 |
| Gill, R | 1 |
| Saksena, S | 1 |
| Hadjiagapiou, C | 1 |
| Mansour, F | 1 |
| Ramaswamy, K | 1 |
| Fu, H | 1 |
| Shi, YQ | 1 |
| Mo, SJ | 1 |
| Knoll, N | 1 |
| Ruhe, C | 1 |
| Veeriah, S | 1 |
| Sauer, J | 1 |
| Glei, M | 1 |
| Gallagher, EP | 1 |
| Pool-Zobel, BL | 1 |
| Bártová, E | 1 |
| Pacherník, J | 1 |
| Harnicarová, A | 1 |
| Kovarík, A | 1 |
| Kovaríková, M | 1 |
| Skalníková, M | 1 |
| Kozubek, M | 1 |
| Kozubek, S | 1 |
| Nguyen, KA | 1 |
| Cao, Y | 1 |
| Chen, JR | 1 |
| Townsend, CM | 2 |
| Ko, TC | 1 |
| Comalada, M | 1 |
| Bailón, E | 1 |
| de Haro, O | 1 |
| Lara-Villoslada, F | 1 |
| Xaus, J | 1 |
| Belinsky, GS | 1 |
| Rajan, TV | 1 |
| Saria, EA | 1 |
| Giardina, C | 1 |
| Rosenberg, DW | 1 |
| Aung, CS | 1 |
| Kruger, WA | 1 |
| Poronnik, P | 1 |
| Roberts-Thomson, SJ | 1 |
| Monteith, GR | 1 |
| Dexter, DL | 2 |
| Lev, R | 1 |
| McKendall, GR | 1 |
| Mitchell, P | 1 |
| Calabres, P | 1 |
| Augeron, C | 1 |
| Laboisse, CL | 1 |
| Tsao, D | 2 |
| Shi, ZR | 1 |
| Wong, A | 1 |
| Kim, YS | 8 |
| Herz, F | 7 |
| Halwer, M | 4 |
| Morita, A | 1 |
| Awad, AB | 3 |
| Kamei, A | 1 |
| Horvath, PJ | 3 |
| Fink, CS | 1 |
| Li, M | 1 |
| Andersen, V | 1 |
| Lance, P | 2 |
| Hague, A | 2 |
| Johnson, IT | 2 |
| Lupton, JR | 2 |
| Patry, Y | 2 |
| Douillard, JY | 2 |
| Meflah, K | 3 |
| Le Pendu, J | 3 |
| Jacewicz, MS | 1 |
| Acheson, DW | 2 |
| Mobassaleh, M | 1 |
| Donohue-Rolfe, A | 1 |
| Balasubramanian, KA | 2 |
| Keusch, GT | 2 |
| Velcich, A | 1 |
| Palumbo, L | 1 |
| Jarry, A | 1 |
| Laboisse, C | 1 |
| Racevskis, J | 1 |
| Augenlicht, L | 2 |
| Berenson, CS | 1 |
| Patterson, MA | 1 |
| Miqdadi, JA | 1 |
| Dang, J | 1 |
| Doe, WF | 1 |
| Morrow, CS | 1 |
| Nakagawa, M | 1 |
| Goldsmith, ME | 1 |
| Madden, MJ | 1 |
| Cowan, KH | 1 |
| Ho, SB | 2 |
| Yan, PS | 1 |
| Dahiya, R | 1 |
| Neuschwander-Tetri, BA | 1 |
| Basbaum, C | 1 |
| Schroy, PC | 1 |
| Rustgi, AK | 1 |
| Ikonomu, E | 1 |
| Liu, XP | 1 |
| Polito, J | 1 |
| Andry, C | 1 |
| O'Keane, JC | 1 |
| Ohannesian, DW | 1 |
| Lotan, D | 1 |
| Lotan, R | 1 |
| Perrin, P | 1 |
| Cassagnau, E | 1 |
| Burg, C | 1 |
| Vavasseur, F | 1 |
| Harb, J | 1 |
| Galmiche, JP | 1 |
| Bornet, F | 1 |
| Chang, AE | 1 |
| Reeder, JA | 1 |
| Dickinson, JL | 1 |
| Chenevix-Trench, G | 1 |
| Antalis, TM | 1 |
| Frommel, TO | 1 |
| Coon, JS | 1 |
| Tsuruo, T | 1 |
| Roninson, IB | 1 |
| Andersen, M | 1 |
| Gope, R | 1 |
| Gope, ML | 1 |
| Musk, SR | 1 |
| Carraro, S | 1 |
| Montiel, M | 1 |
| Celener, D | 1 |
| Pons, S | 1 |
| Navigante, A | 1 |
| Bustos, D | 1 |
| Bustos Fernández, L | 1 |
| Bartram, HP | 1 |
| Scheppach, W | 1 |
| Schmid, H | 1 |
| Hofmann, A | 1 |
| Dusel, G | 1 |
| Richter, F | 1 |
| Richter, A | 1 |
| Kasper, H | 1 |
| Souleimani, A | 2 |
| Asselin, C | 2 |
| Barnard, JA | 1 |
| Warwick, G | 1 |
| Manning, AM | 1 |
| Hanlon, KA | 1 |
| Huschtscha, LI | 1 |
| Hart, D | 1 |
| Desai, TK | 1 |
| Nathan, DF | 2 |
| Morin, MJ | 2 |
| Kvale, D | 1 |
| Brandtzaeg, P | 1 |
| Clausen, MR | 1 |
| Sharma, HW | 1 |
| Sokoloski, JA | 1 |
| Perez, JR | 1 |
| Maltese, JY | 1 |
| Sartorelli, AC | 1 |
| Stein, CA | 1 |
| Nichols, G | 1 |
| Khaled, Z | 1 |
| Telang, NT | 1 |
| Narayanan, R | 1 |
| Velázquez, OC | 2 |
| Lederer, HM | 1 |
| Rombeau, JL | 2 |
| Moore, R | 1 |
| De Breucker, S | 1 |
| Lincicome, L | 1 |
| Jacewicz, M | 1 |
| Skutelsky, E | 1 |
| McBain, JA | 2 |
| Eastman, A | 2 |
| Simmons, DL | 1 |
| Pettit, GR | 1 |
| Mueller, GC | 2 |
| Hanski, C | 1 |
| Klussmann, E | 1 |
| Wang, J | 1 |
| Böhm, C | 1 |
| Ogorek, D | 1 |
| Hanski, ML | 1 |
| Krüger-Krasagakes, S | 1 |
| Eberle, J | 1 |
| Schmitt-Gräff, A | 1 |
| Riecken, EO | 1 |
| Li, S | 1 |
| Ke, S | 1 |
| Budde, RJ | 1 |
| Marchetti, C | 1 |
| Migliorati, G | 2 |
| Moraca, R | 2 |
| Riccardi, C | 2 |
| Nicoletti, I | 2 |
| Fabiani, R | 2 |
| Mastrandrea, V | 2 |
| Morozzi, G | 2 |
| Benard, O | 1 |
| Russo, GL | 2 |
| Della Pietra, V | 2 |
| Mercurio, C | 2 |
| Della Ragione, F | 1 |
| Marshak, DR | 1 |
| Oliva, A | 1 |
| Zappia, V | 2 |
| Marchetti, MC | 1 |
| Singh, B | 1 |
| Halestrap, AP | 1 |
| Nobel, CS | 1 |
| Navarro, JM | 1 |
| Olmo, N | 1 |
| Turnay, J | 1 |
| López-Conejo, MT | 1 |
| Lizarbe, MA | 1 |
| Nakano, K | 1 |
| Mizuno, T | 1 |
| Sowa, Y | 1 |
| Orita, T | 1 |
| Yoshino, T | 1 |
| Okuyama, Y | 1 |
| Fujita, T | 1 |
| Ohtani-Fujita, N | 1 |
| Matsukawa, Y | 1 |
| Tokino, T | 1 |
| Yamagishi, H | 1 |
| Oka, T | 1 |
| Nomura, H | 1 |
| Sakai, T | 1 |
| Birkett, AM | 1 |
| Jones, GP | 1 |
| de Silva, AM | 1 |
| Young, GP | 1 |
| Muir, JG | 1 |
| Hassig, CA | 1 |
| Tong, JK | 1 |
| Schreiber, SL | 1 |
| Palmer, DG | 1 |
| Cordel, S | 1 |
| Heymann, MF | 1 |
| Boisteau, O | 1 |
| Oliver, L | 1 |
| Grégoire, M | 2 |
| Archer, SY | 1 |
| Meng, S | 1 |
| Shei, A | 1 |
| Luceri, C | 1 |
| Lancioni, L | 1 |
| Tessitore, L | 1 |
| Dolara, P | 1 |
| Heerdt, BG | 1 |
| Houston, MA | 1 |
| Anthony, GM | 1 |
| Zhang, J | 1 |
| Wu, G | 1 |
| Chapkin, RS | 1 |
| Nishimura, A | 1 |
| Fujimoto, M | 1 |
| Oguchi, S | 1 |
| Fusunyan, RD | 1 |
| MacDermott, RP | 1 |
| Sanderson, IR | 1 |
| Mandal, M | 1 |
| Adam, L | 1 |
| Mendelsohn, J | 1 |
| Kumar, R | 1 |
| Bonnotte, B | 1 |
| Favre, N | 1 |
| Reveneau, S | 1 |
| Micheau, O | 1 |
| Droin, N | 1 |
| Garrido, C | 1 |
| Fontana, A | 1 |
| Chauffert, B | 1 |
| Solary, E | 1 |
| Martin, F | 1 |
| Henry, F | 1 |
| Bretaudeau, L | 1 |
| Hequet, A | 1 |
| Barbieux, I | 1 |
| Lieubeau, B | 1 |
| Palumbo, R | 1 |
| Iacomino, G | 1 |
| Russo, M | 1 |
| Tosto, M | 1 |
| D'Argenio, G | 1 |
| Mazzacca, G | 1 |
| Haza, AI | 1 |
| Glinghammar, B | 1 |
| Grandien, A | 1 |
| Rafter, J | 1 |
| Vider, BZ | 1 |
| Zimber, A | 1 |
| Chastre, E | 1 |
| Gespach, C | 1 |
| Halperin, M | 1 |
| Mashiah, P | 1 |
| Yaniv, A | 1 |
| Gazit, A | 1 |
| Coradini, D | 2 |
| Pellizzaro, C | 2 |
| Marimpietri, D | 1 |
| Abolafio, G | 1 |
| Daidone, MG | 2 |
| Nancey, S | 1 |
| Coffin, B | 1 |
| Descos, L | 1 |
| Flourié, B | 1 |
| Andoh, A | 1 |
| Shimada, M | 1 |
| Araki, Y | 1 |
| Fujiyama, Y | 1 |
| Bamba, T | 1 |
| Kashtan, H | 1 |
| Stern, HS | 1 |
| Jenkins, DJ | 1 |
| Jenkins, AL | 1 |
| Thompson, LU | 1 |
| Hay, K | 1 |
| Marcon, N | 1 |
| Minkin, S | 1 |
| Bruce, WR | 1 |
| Kondoh, N | 1 |
| Schweinfest, CW | 1 |
| Henderson, KW | 1 |
| Papas, TS | 1 |
| Parekh, D | 1 |
| Saydjari, R | 1 |
| Ishizuka, J | 1 |
| Thompson, JC | 1 |
| Gamet, L | 1 |
| Daviaud, D | 1 |
| Denis-Pouxviel, C | 1 |
| Remesy, C | 1 |
| Murat, JC | 1 |
| Taylor, CW | 1 |
| Childress-Fields, KE | 1 |
| Yeoman, LC | 1 |
| Lewis, LR | 1 |
| Levine, AE | 1 |
| Collins, JF | 1 |
| Herman, P | 1 |
| Schuch, C | 1 |
| Bagby, GC | 1 |
| Deng, G | 1 |
| Liu, G | 1 |
| Hu, L | 1 |
| Gum, JR | 3 |
| Andersen, MS | 1 |
| Burkhart, SR | 1 |
| Walling, JM | 1 |
| Blackmore, M | 1 |
| Hickman, JA | 1 |
| Townsend, KM | 1 |
| Murphy, LD | 1 |
| Valverius, EM | 1 |
| Tsokos, M | 1 |
| Mickley, LA | 2 |
| Rosen, N | 3 |
| Bates, SE | 2 |
| Tanaka, Y | 1 |
| Bush, KK | 1 |
| Eguchi, T | 1 |
| Ikekawa, N | 1 |
| Taguchi, T | 1 |
| Kobayashi, Y | 1 |
| Higgins, PJ | 1 |
| Harper, SJ | 1 |
| Arundel, CM | 4 |
| Leith, JT | 6 |
| Friedman, J | 1 |
| Seger, M | 1 |
| Levinsky, H | 1 |
| Allalouf, D | 1 |
| Foss, FM | 1 |
| Veillette, A | 1 |
| Sartor, O | 1 |
| Bolen, JB | 1 |
| Sussman, NL | 1 |
| Eliakim, R | 1 |
| Rubin, D | 1 |
| Perlmutter, DH | 1 |
| DeSchryver-Kecskemeti, K | 1 |
| Alpers, DH | 1 |
| Richert, ND | 1 |
| Currier, S | 1 |
| Tanaka, S | 1 |
| Foss, F | 1 |
| Fojo, AT | 1 |
| Toribara, NW | 1 |
| Sack, TL | 1 |
| Shively, JE | 1 |
| Willson, JK | 1 |
| Otaka, M | 1 |
| Singhal, A | 1 |
| Hakomori, S | 1 |
| Czerniak, B | 1 |
| Wersto, RP | 1 |
| Koss, LG | 1 |
| Kéri, G | 1 |
| Balogh, A | 1 |
| Teplán, I | 1 |
| Csuka, O | 1 |
| Berry, RD | 1 |
| Niles, RM | 1 |
| Wilhelm, SA | 1 |
| Thomas, P | 1 |
| Zamcheck, N | 1 |
| Hallows, KT | 1 |
| Bliven, SF | 1 |
| Kenney, SM | 1 |
| Glicksman, AS | 2 |
| Freeman, HJ | 1 |
| Kam, WK | 1 |
| Byrd, JC | 1 |
| Hicks, JW | 1 |
| Sleisenger, MH | 2 |
| Chung, YS | 1 |
| Song, IS | 1 |
| Erickson, RH | 1 |
| Dibner, MD | 1 |
| Ireland, KA | 1 |
| Koerner, LA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Efficacy and Safety Assessment of Oral LBH589 in Adult Patients With Advanced Soft Tissue Sarcoma After Pre-treatment Failure: an Open-label, Multicenter Phase II Study[NCT01136499] | Phase 2 | 53 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| A Randomized Controlled Trial to Evaluate the Effects of Repeated Periods of Modified Fasting to Support Healthy Natural Weight Management and Prevention of Weight Gain in Overweight But Generally Healthy Adults Over the Winter Holiday Period[NCT03372109] | 23 participants (Actual) | Interventional | 2017-11-14 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for butyric acid and Colonic Neoplasms
| Article | Year |
|---|---|
Vimentin, colon cancer progression and resistance to butyrate and other HDACis.
Topics: Animals; Butyric Acid; Colonic Neoplasms; Disease Progression; Drug Resistance, Neoplasm; Histone De | 2016 |
The short-chain fatty acid butyrate induces apoptosis in colorectal tumour cell lines.
Topics: Adenoma; Apoptosis; Butyrates; Butyric Acid; Carcinoma; Cell Survival; Colonic Neoplasms; Dose-Respo | 1995 |
Butyrate and markers of neoplastic change in the colon.
Topics: Alkaline Phosphatase; Biomarkers, Tumor; Butyrates; Butyric Acid; Cell Division; Colitis, Ulcerative | 1995 |
Butyrate and colonic cytokinetics: differences between in vitro and in vivo studies.
Topics: Animals; Apoptosis; Butyrates; Butyric Acid; Cell Cycle; Cell Differentiation; Cell Division; Coloni | 1995 |
Butyrate and colorectal cancer in animals and in humans (mini-symposium: butyrate and colorectal cancer).
Topics: Animals; Butyrates; Butyric Acid; Carcinogens; Colonic Neoplasms; Fatty Acids, Volatile; Humans; Rec | 1995 |
Butyrate and the colonocyte. Implications for neoplasia.
Topics: Animals; Butyrates; Butyric Acid; Colon; Colonic Neoplasms; Dietary Carbohydrates; Dietary Fats; Die | 1996 |
Butyrate. Potential role in colon cancer prevention and treatment.
Topics: Animals; Anticarcinogenic Agents; Butyrates; Butyric Acid; Colonic Neoplasms; Deoxycholic Acid; Diet | 1997 |
Fiber-derived butyrate and the prevention of colon cancer.
Topics: Binding Sites; Butyrates; Butyric Acid; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cy | 1997 |
Protective effects of butyric acid in colon cancer.
Topics: Apoptosis; Butyric Acid; Casein Kinase II; Cell Division; Colonic Neoplasms; Dietary Fiber; Humans; | 1999 |
Short-chain fatty acid in the human colon. Relation to inflammatory bowel diseases and colon cancer.
Topics: Butyric Acid; Colon; Colonic Neoplasms; Dietary Fiber; Fatty Acids; Humans; Inflammatory Bowel Disea | 1999 |
135 other studies available for butyric acid and Colonic Neoplasms
| Article | Year |
|---|---|
In vitro studies on the inhibition of colon cancer by amino acid derivatives of bromothiazole.
Topics: Amino Acids; Antineoplastic Agents; Apoptosis; Caco-2 Cells; Cell Proliferation; Colon; Colonic Neop | 2017 |
A novel dual-prodrug carried by cyclodextrin inclusion complex for the targeting treatment of colon cancer.
Topics: Animals; Antineoplastic Agents; Butyric Acid; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasm | 2021 |
Metabolomics of Acute vs. Chronic Spinach Intake in an Apc-Mutant Genetic Background: Linoleate and Butanoate Metabolites Targeting HDAC Activity and IFN-γ Signaling.
Topics: Animals; Butyric Acid; Colonic Neoplasms; Diet; Humans; Interferon-gamma; Linoleic Acid; Metabolomic | 2022 |
Lactiplantibacillus plantarum inhibits colon cancer cell proliferation as function of its butyrogenic capability.
Topics: Butyric Acid; Cell Proliferation; Colonic Neoplasms; Cyclin D1; Humans; Lactobacillaceae | 2022 |
Effect of Sodium Butyrate on p16INK4a, p14ARF, p15INK4b, Class I HDACs (HDACs 1, 2, 3) Class II HDACs (HDACs 4, 5, 6), Cell Growth Inhibition and Apoptosis Induction in Pancreatic Cancer AsPC-1 and Colon Cancer HCT-116 Cell Lines.
Topics: Apoptosis; Butyric Acid; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p15; Cyclin-Dependent | 2022 |
Butyrate Drives Metabolic Rewiring and Epigenetic Reprogramming in Human Colon Cancer Cells.
Topics: Butyric Acid; Colonic Neoplasms; DNA Methylation; Epigenesis, Genetic; Epigenomics; Histone Demethyl | 2022 |
Butyrate enhances the efficacy of radiotherapy via FOXO3A in colorectal cancer patient‑derived organoids.
Topics: Aged; Aged, 80 and over; Butyric Acid; Cell Culture Techniques; Chemoradiotherapy, Adjuvant; Colecto | 2020 |
The Interplay between Fe
Topics: Adenocarcinoma; Antineoplastic Agents; Butyric Acid; Cell Line; Cell Line, Tumor; Cell Survival; Col | 2020 |
Colon cancer cell differentiation by sodium butyrate modulates metabolic plasticity of Caco-2 cells via alteration of phosphotransfer network.
Topics: Antineoplastic Agents; Butyric Acid; Caco-2 Cells; Cell Differentiation; Colonic Neoplasms; Energy M | 2021 |
Tributyltin(IV) Butyrate: A Novel Epigenetic Modifier with ER Stress- and Apoptosis-Inducing Properties in Colon Cancer Cells.
Topics: Acetylation; Apoptosis; Butyric Acid; Cell Line, Tumor; Colonic Neoplasms; Endoplasmic Reticulum Str | 2021 |
Differentiation Affects the Release of Exosomes from Colon Cancer Cells and Their Ability to Modulate the Behavior of Recipient Cells.
Topics: AC133 Antigen; Butyric Acid; Caco-2 Cells; Cell Differentiation; Cell Movement; Cell Proliferation; | 2017 |
Pomegranate By-Products in Colorectal Cancer Chemoprevention: Effects in Apc-Mutated Pirc Rats and Mechanistic Studies In Vitro and Ex Vivo.
Topics: Adenoma; Adenomatous Polyposis Coli Protein; Animals; Anticarcinogenic Agents; Apoptosis; Butyric Ac | 2018 |
In vitro activities of inulin fermentation products to HCT-116 cells enhanced by the cooperation between exogenous strains and adult faecal microbiota.
Topics: Acetates; Apoptosis; Butyric Acid; Colonic Neoplasms; DNA Fragmentation; Enterococcus; Feces; Fermen | 2018 |
Oral administration of antibiotics results in fecal occult bleeding due to metabolic disorders and defective proliferation of the gut epithelial cell in mice.
Topics: Administration, Oral; Ampicillin; Animals; Anti-Bacterial Agents; Antimicrobial Cationic Peptides; B | 2018 |
CD49f-positive cell population efficiently enriches colon cancer-initiating cells.
Topics: AC133 Antigen; Activated-Leukocyte Cell Adhesion Molecule; Animals; Antigens, CD; Biomarkers, Tumor; | 2013 |
Green tea phenolics inhibit butyrate-induced differentiation of colon cancer cells by interacting with monocarboxylate transporter 1.
Topics: Adenocarcinoma; Alkaline Phosphatase; Anticarcinogenic Agents; Apoptosis; Blotting, Western; Butyric | 2013 |
Molecular mechanisms for inhibition of colon cancer cells by combined epigenetic-modulating epigallocatechin gallate and sodium butyrate.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Butyric Acid; Catechin; Cell Cycle Checkp | 2014 |
The intestinal epithelial cell differentiation marker intestinal alkaline phosphatase (ALPi) is selectively induced by histone deacetylase inhibitors (HDACi) in colon cancer cells in a Kruppel-like factor 5 (KLF5)-dependent manner.
Topics: Alkaline Phosphatase; Benzamides; Binding Sites; Blotting, Western; Butyric Acid; Cell Differentiati | 2014 |
Impact of sodium butyrate on the network of adhesion/growth-regulatory galectins in human colon cancer in vitro.
Topics: Alkaline Phosphatase; Biomarkers; Butyric Acid; Cell Adhesion; Cell Line, Tumor; Cell Proliferation; | 2014 |
Slc5a8, a Na+-coupled high-affinity transporter for short-chain fatty acids, is a conditional tumour suppressor in colon that protects against colitis and colon cancer under low-fibre dietary conditions.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Butyric Acid; Cation Transport Pro | 2015 |
Activation of autophagy and PPARγ protect colon cancer cells against apoptosis induced by interactive effects of butyrate and DHA in a cell type-dependent manner: The role of cell differentiation.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Butyrates; Butyric Acid; Caspase 3; Cell Differentiatio | 2017 |
HDAC inhibitors show differential epigenetic regulation and cell survival strategies on p53 mutant colon cancer cells.
Topics: Benzamides; Butyric Acid; Cell Survival; Colonic Neoplasms; Computer Simulation; DNA Methylation; Ep | 2018 |
Dietary fiber down-regulates colonic tumor necrosis factor alpha and nitric oxide production in trinitrobenzenesulfonic acid-induced colitic rats.
Topics: Adenocarcinoma; Animals; Butyric Acid; Colitis; Colon; Colonic Neoplasms; Dietary Fiber; Female; Glu | 2002 |
Opposing effects of butyrate and bile acids on apoptosis of human colon adenoma cells: differential activation of PKC and MAP kinases.
Topics: Adenoma; Apoptosis; Butyric Acid; Caspase 3; Caspase Inhibitors; Colonic Neoplasms; Cysteine Protein | 2003 |
Transcriptional upregulation of the insulin-like growth factor binding protein IGFBP-3 by sodium butyrate increases IGF-independent apoptosis in human colonic adenoma-derived epithelial cells.
Topics: Adenoma; Apoptosis; Blotting, Northern; Butyric Acid; Colonic Neoplasms; Epithelial Cells; Humans; I | 2003 |
Regulation of butyrate uptake in Caco-2 cells by phorbol 12-myristate 13-acetate.
Topics: Adenocarcinoma; Butyric Acid; Caco-2 Cells; Carcinogens; Colonic Neoplasms; Drug Administration Sche | 2004 |
Effect of short-chain fatty acids on the proliferation and differentiation of the human colonic adenocarcinoma cell line Caco-2.
Topics: Acetic Acid; Adenocarcinoma; Butyric Acid; Caco-2 Cells; Cell Differentiation; Cell Movement; Cell P | 2004 |
Genotoxicity of 4-hydroxy-2-nonenal in human colon tumor cells is associated with cellular levels of glutathione and the modulation of glutathione S-transferase A4 expression by butyrate.
Topics: Aldehydes; Base Sequence; Butyric Acid; Cell Line, Tumor; Colonic Neoplasms; Comet Assay; DNA Primer | 2005 |
Nuclear levels and patterns of histone H3 modification and HP1 proteins after inhibition of histone deacetylases.
Topics: Apoptosis; Butyric Acid; Carcinoma, Small Cell; Cell Cycle; Cell Line; Cell Line, Tumor; Cell Nucleu | 2005 |
Dietary fiber enhances a tumor suppressor signaling pathway in the gut.
Topics: Animals; Butyric Acid; Cells, Cultured; Colonic Neoplasms; Dietary Fiber; Epithelial Cells; Humans; | 2006 |
The effects of short-chain fatty acids on colon epithelial proliferation and survival depend on the cellular phenotype.
Topics: Adenocarcinoma; Alkaline Phosphatase; Animals; Apoptosis; Blotting, Western; Butyric Acid; Cell Prol | 2006 |
Expression of secretory phospholipase A2 in colon tumor cells potentiates tumor growth.
Topics: Arachidonic Acid; Base Sequence; Butyric Acid; Cell Division; Cell Line, Tumor; Colonic Neoplasms; D | 2007 |
Plasma membrane Ca2+-ATPase expression during colon cancer cell line differentiation.
Topics: Alkaline Phosphatase; Butyric Acid; Calcium-Transporting ATPases; Cell Differentiation; Cell Line, T | 2007 |
Sodium butyrate-induced alteration of growth properties and glycogen levels in cultured human colon carcinoma cells.
Topics: Butyrates; Butyric Acid; Cell Line; Clone Cells; Colonic Neoplasms; Glycogen; Humans | 1984 |
Emergence of permanently differentiated cell clones in a human colonic cancer cell line in culture after treatment with sodium butyrate.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Clone Cells; Colonic Neoplasms; Humans; My | 1984 |
Effect of sodium butyrate on carcinoembryonic antigen production by human colonic adenocarcinoma cells in culture.
Topics: Adenocarcinoma; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Line; Colonic Neoplasms; Gly | 1983 |
Preferential alkaline phosphatase isoenzyme induction by sodium butyrate.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Line; Clone Cells; Colonic Neoplasms; Enzyme Ind | 1983 |
Effect of sodium butyrate on alkaline phosphatase in HRT-18, a human rectal cancer cell line.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Line; Colonic Neoplasms; Cycloheximide; Dactinom | 1982 |
Synergistic induction of alkaline phosphatase in colonic carcinoma cells by sodium butyrate and hyperosmolality.
Topics: Adenocarcinoma; Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Line; Colonic Neoplasms; Enzyme | 1982 |
Prostaglandin synthesis in human cancer cells: influence of fatty acids and butyrate.
Topics: Butyrates; Butyric Acid; Cell Division; Cell Membrane; Colonic Neoplasms; Dinoprostone; Epoprostenol | 1995 |
Expression and regulation of glycosyltransferases for N-glycosyl oligosaccharides in fresh human surgical and murine tissues and cultured cell lines.
Topics: Adenocarcinoma; Animals; beta-D-Galactoside alpha 2-6-Sialyltransferase; Blotting, Northern; Butyrat | 1995 |
Immunization against a rat colon carcinoma by sodium butyrate-treated cells but not by interleukin 2-secreting cells.
Topics: Animals; BCG Vaccine; Butyrates; Butyric Acid; Colonic Neoplasms; Interleukin-2; Lymphocyte Depletio | 1995 |
Maturational regulation of globotriaosylceramide, the Shiga-like toxin 1 receptor, in cultured human gut epithelial cells.
Topics: Adenocarcinoma; Bacterial Toxins; Butyrates; Butyric Acid; Cell Line; Cell Survival; Colonic Neoplas | 1995 |
Patterns of expression of lineage-specific markers during the in vitro-induced differentiation of HT29 colon carcinoma cells.
Topics: Alkaline Phosphatase; Antigens, Differentiation; Antigens, Neoplasm; Biomarkers; Butyrates; Butyric | 1995 |
n-Butyrate mediation of ganglioside expression of human and murine cancer cells demonstrates relative cell specificity.
Topics: Animals; Butyrates; Butyric Acid; Cell Line; Chromatography, Thin Layer; Colonic Neoplasms; Dose-Res | 1995 |
Sodium butyrate inhibits expression of urokinase and its receptor mRNAs at both transcription and post-transcription levels in colon cancer cells.
Topics: Butyrates; Butyric Acid; Cell Nucleus; Colonic Neoplasms; Cycloheximide; Gene Expression; Humans; Ph | 1995 |
Reversible transcriptional activation of mdr1 by sodium butyrate treatment of human colon cancer cells.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Butyrates; Butyric Acid; Carrier Proteins; | 1994 |
Stable differentiation of a human colon adenocarcinoma cell line by sodium butyrate is associated with multidrug resistance.
Topics: Adenocarcinoma; Aminopeptidases; Animals; Antigens, Neoplasm; ATP Binding Cassette Transporter, Subf | 1994 |
Growth and intestinal differentiation are independently regulated in HT29 colon cancer cells.
Topics: Acetamides; Antineoplastic Agents; Biomarkers; Butyrates; Butyric Acid; Cell Differentiation; Cell D | 1994 |
Concomitant increases in galectin-1 and its glycoconjugate ligands (carcinoembryonic antigen, lamp-1, and lamp-2) in cultured human colon carcinoma cells by sodium butyrate.
Topics: Animals; Antigens, CD; Antigens, Differentiation; Butyrates; Butyric Acid; Carcinoembryonic Antigen; | 1994 |
An interleukin 2/sodium butyrate combination as immunotherapy for rat colon cancer peritoneal carcinomatosis.
Topics: Adenocarcinoma; Animals; Antigen-Presenting Cells; Butyrates; Butyric Acid; Colonic Neoplasms; Combi | 1994 |
Perspectives on interleukin-2 immunotherapy for colon cancer.
Topics: Animals; Butyrates; Butyric Acid; Colonic Neoplasms; Immunotherapy; Interleukin-2; Peritoneal Neopla | 1994 |
Sodium butyrate differentially modulates plasminogen activator inhibitor type-1, urokinase plasminogen activator, and its receptor in a human colon carcinoma cell.
Topics: Base Sequence; Butyrates; Butyric Acid; Cell Division; Colonic Neoplasms; Dose-Response Relationship | 1993 |
Variable effects of sodium butyrate on the expression and function of the MDR1 (P-glycoprotein) gene in colon carcinoma cell lines.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Butyrates; Butyric Acid; Carcinoma; Carrier | 1993 |
Differential effect of butyrate on lipids of human colon cancer cells.
Topics: Butyrates; Butyric Acid; Colonic Neoplasms; Fatty Acids; Humans; Lipid Metabolism; Phospholipids; Tr | 1993 |
Effect of sodium butyrate on the expression of retinoblastoma (RB1) and P53 gene and phosphorylation of retinoblastoma protein in human colon tumor cell line HT29.
Topics: Adenocarcinoma; Butyrates; Butyric Acid; Cell Differentiation; Colonic Neoplasms; Depression, Chemic | 1993 |
Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29.
Topics: Butyrates; Butyric Acid; Cell Division; Cell Line, Transformed; Cell Survival; Colonic Neoplasms; Di | 1993 |
[Influence of sodium butyrate intake on murine colonic carcinogenesis].
Topics: Animals; Butyrates; Butyric Acid; Colectomy; Colonic Neoplasms; Dimethylhydrazines; Feces; Male; Rat | 1993 |
Proliferation of human colonic mucosa as an intermediate biomarker of carcinogenesis: effects of butyrate, deoxycholate, calcium, ammonia, and pH.
Topics: Adult; Aged; Aged, 80 and over; Ammonia; Butyrates; Butyric Acid; Calcium; Calcium Chloride; Cell Di | 1993 |
Regulation of c-myc expression by sodium butyrate in the colon carcinoma cell line Caco-2.
Topics: Blotting, Northern; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Colonic Neoplasms; | 1993 |
Butyrate rapidly induces growth inhibition and differentiation in HT-29 cells.
Topics: Adenocarcinoma; Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; | 1993 |
Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer.
Topics: Adenoma; Apoptosis; Butyrates; Butyric Acid; Carcinoma; Colonic Neoplasms; Dietary Fiber; DNA, Neopl | 1993 |
Divergent effects of butyrate on the alkaline phosphatases of SW-620 cells.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Colonic Neoplasms; Enzyme Induction; Enzyme Stability | 1993 |
Regulation of C-fos expression by sodium butyrate in the human colon carcinoma cell line Caco-2.
Topics: Activating Transcription Factors; Adenocarcinoma; Base Sequence; Blood Proteins; Butyrates; Butyric | 1993 |
Potentiation of butyrate-induced differentiation in human colon tumor cells by deoxycholate.
Topics: Adenocarcinoma; Alkaline Phosphatase; beta-Galactosidase; Butyrates; Butyric Acid; Cell Differentiat | 1993 |
Butyrate differentially affects constitutive and cytokine-induced expression of HLA molecules, secretory component (SC), and ICAM-1 in a colonic epithelial cell line (HT-29, clone m3).
Topics: Adenocarcinoma; Antigens, Neoplasm; Bacteria, Anaerobic; Butyrates; Butyric Acid; Cell Division; Col | 1995 |
Differentiation of immortal cells inhibits telomerase activity.
Topics: Animals; Base Sequence; Butyrates; Butyric Acid; Calcitriol; Cell Differentiation; Cell Line; Cell N | 1995 |
Translocation of Shiga toxin across polarized intestinal cells in tissue culture.
Topics: Animals; Bacterial Toxins; Biological Transport; Butyrates; Butyric Acid; Carcinoma; Cell Polarity; | 1996 |
Phorbol ester augments butyrate-induced apoptosis of colon cancer cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Apoptosis; Bryostatins; Butyrates; Butyric Acid; Cell Divisio | 1996 |
Fucosyltransferase III and sialyl-Le(x) expression correlate in cultured colon carcinoma cells but not in colon carcinoma tissue.
Topics: Antibodies, Monoclonal; Blotting, Northern; Butyrates; Butyric Acid; Colonic Neoplasms; Dimethyl Sul | 1996 |
The C-terminal Src kinase (Csk) is widely expressed, active in HT-29 cells that contain activated Src, and its expression is downregulated in butyrate-treated SW620 cells.
Topics: Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Colonic Neoplasms; CSK Tyrosine-Pro | 1996 |
The 3' untranslated region of the carcinoembryonic antigen gene plays a minimal role in the regulation of gene expression.
Topics: Aged; Aged, 80 and over; Base Sequence; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Colonic N | 1997 |
Deoxycholic acid and SCFA-induced apoptosis in the human tumor cell-line HT-29 and possible mechanisms.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Apoptosis; Butyrates; Butyric Acid; Calcium; Chelatin | 1997 |
Modulation of glutathione level during butyrate-induced differentiation in human colon derived HT-29 cells.
Topics: Alkaline Phosphatase; Buthionine Sulfoximine; Butyrates; Butyric Acid; Cell Differentiation; Cell Di | 1997 |
Down-regulation of protein kinase CKII activity by sodium butyrate.
Topics: Adenocarcinoma; Amino Acid Sequence; Butyrates; Butyric Acid; Casein Kinase II; Cell Differentiation | 1997 |
Possible mechanisms involved in apoptosis of colon tumor cell lines induced by deoxycholic acid, short-chain fatty acids, and their mixtures.
Topics: Apoptosis; Butyrates; Butyric Acid; Calcium; Chelating Agents; Colonic Neoplasms; Deoxycholic Acid; | 1997 |
Butyrate can act as a stimulator of growth or inducer of apoptosis in human colonic epithelial cell lines depending on the presence of alternative energy sources.
Topics: Adenoma; Apoptosis; Butyrates; Butyric Acid; Cell Division; Cell Line; Colon; Colonic Neoplasms; Cul | 1997 |
Apoptotic death in adenocarcinoma cell lines induced by butyrate and other histone deacetylase inhibitors.
Topics: Adenocarcinoma; Apoptosis; Butyrates; Butyric Acid; Colonic Neoplasms; Dose-Response Relationship, D | 1997 |
Differentiation of BCS-TC2 human colon adenocarcinoma cells by sodium butyrate: increase in 5'-nucleotidase activity.
Topics: 5'-Nucleotidase; Adenocarcinoma; Apoptosis; Biomarkers, Tumor; Butyrates; Butyric Acid; Carcinoembry | 1997 |
Butyrate activates the WAF1/Cip1 gene promoter through Sp1 sites in a p53-negative human colon cancer cell line.
Topics: Base Sequence; Blotting, Western; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Colo | 1997 |
Dietary intake and faecal excretion of carbohydrate by Australians: importance of achieving stool weights greater than 150 g to improve faecal markers relevant to colon cancer risk.
Topics: Adolescent; Adult; Aged; Ammonia; Australia; Biomarkers, Tumor; Butyrates; Butyric Acid; Colonic Neo | 1997 |
Modulation of p53 expression in cultured colonic adenoma cell lines by the naturally occurring lumenal factors butyrate and deoxycholate.
Topics: Adenoma; Butyrates; Butyric Acid; Cell Division; Cholagogues and Choleretics; Colonic Neoplasms; Deo | 1997 |
5-Fluorouracil-resistant colonic tumors are highly responsive to sodium butyrate/interleukin-2 bitherapy in rats.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Butyrates; | 1997 |
p21(WAF1) is required for butyrate-mediated growth inhibition of human colon cancer cells.
Topics: Butyrates; Butyric Acid; Cell Division; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cy | 1998 |
Slow-release pellets of sodium butyrate increase apoptosis in the colon of rats treated with azoxymethane, without affecting aberrant crypt foci and colonic proliferation.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Azoxymethane; Biomarkers, Tumor; Butyrates; Butyric Aci | 1998 |
Mitochondrial membrane potential (delta psi(mt)) in the coordination of p53-independent proliferation and apoptosis pathways in human colonic carcinoma cells.
Topics: Apoptosis; Butyrates; Butyric Acid; Cell Aggregation; Cell Division; Colonic Neoplasms; Cyclin-Depen | 1998 |
Energy metabolism of rat colonocytes changes during the tumorigenic process and is dependent on diet and carcinogen.
Topics: 3-Hydroxybutyric Acid; Animals; Azoxymethane; Butyrates; Butyric Acid; Carcinogens; Cellulose; Colon | 1998 |
Short-chain fatty acids regulate IGF-binding protein secretion by intestinal epithelial cells.
Topics: Adenocarcinoma; Butyrates; Butyric Acid; Cell Line; Cell Membrane; Cell Polarity; Colonic Neoplasms; | 1998 |
Nuclear targeting of Bax during apoptosis in human colorectal cancer cells.
Topics: Antibodies, Monoclonal; Apoptosis; bcl-2-Associated X Protein; Biological Transport; Butyrates; Buty | 1998 |
Cancer cell sensitization to fas-mediated apoptosis by sodium butyrate.
Topics: Adaptor Proteins, Signal Transducing; Animals; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; | 1998 |
Role of antigen-presenting cells in long-term antitumor response based on tumor-derived apoptotic body vaccination.
Topics: Animals; Antigen-Presenting Cells; Apoptosis; Butyric Acid; Cancer Vaccines; Colonic Neoplasms; Dend | 1999 |
Effect of colonic luminal components on induction of apoptosis in human colonic cell lines.
Topics: Apoptosis; Bile Acids and Salts; Butyric Acid; Cell Line; Colon; Colonic Neoplasms; DNA; DNA Fragmen | 2000 |
Deregulated expression of homeobox-containing genes, HOXB6, B8, C8, C9, and Cdx-1, in human colon cancer cell lines.
Topics: Adenocarcinoma; Adenomatous Polyposis Coli; Butyric Acid; Cell Count; Cell Differentiation; Colonic | 2000 |
Sodium butyrate modulates cell cycle-related proteins in HT29 human colonic adenocarcinoma cells.
Topics: Adenocarcinoma; Butyric Acid; Cell Cycle; Cell Cycle Proteins; Cell Division; Colonic Neoplasms; HT2 | 2000 |
[Colonic microflora and cancer].
Topics: Adenoma; Animals; Bacteria; Bile Acids and Salts; Butyric Acid; Carcinogens; Colon; Colonic Neoplasm | 2001 |
Sodium butyrate enhances complement-mediated cell injury via down-regulation of decay-accelerating factor expression in colonic cancer cells.
Topics: Antineoplastic Agents; Butyric Acid; CD55 Antigens; Colonic Neoplasms; Complement System Proteins; D | 2002 |
Modulation of angiogenesis-related proteins synthesis by sodium butyrate in colon cancer cell line HT29.
Topics: Butyric Acid; Colonic Neoplasms; Endothelial Growth Factors; HT29 Cells; Humans; Hypoxia-Inducible F | 2002 |
Colonic fermentation and markers of colorectal-cancer risk.
Topics: Butyrates; Butyric Acid; Colon; Colonic Neoplasms; Dietary Fiber; DNA; Edible Grain; Feces; Female; | 1992 |
Differential expression of S19 ribosomal protein, laminin-binding protein, and human lymphocyte antigen class I messenger RNAs associated with colon carcinoma progression and differentiation.
Topics: Amino Acid Sequence; Animals; Base Sequence; Blotting, Northern; Butyrates; Butyric Acid; Cell Diffe | 1992 |
Sodium butyrate stimulates polyamine biosynthesis in colon cancer cells.
Topics: Animals; Biogenic Polyamines; Biological Transport; Butyrates; Butyric Acid; Colonic Neoplasms; Dose | 1992 |
Effects of short-chain fatty acids on growth and differentiation of the human colon-cancer cell line HT29.
Topics: Acetates; Acetic Acid; Adenocarcinoma; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; | 1992 |
Sensitivity of nuclear c-myc levels and induction to differentiation-inducing agents in human colon tumor cell lines.
Topics: Butyrates; Butyric Acid; Cell Division; Cell Nucleus; Colonic Neoplasms; Dimethylformamide; Electrop | 1992 |
Sodium butyrate alters the response of a human colon carcinoma cell line to transforming growth factor-beta 1.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Carcinoma; Cell Differentiation; Cell Division; Colon | 1992 |
c-myc antisense oligonucleotides inhibit the colony-forming capacity of Colo 320 colonic carcinoma cells.
Topics: Butyrates; Butyric Acid; Carcinoma; Cell Differentiation; Cell Division; Colonic Neoplasms; Gene Exp | 1992 |
Transcriptional regulation of the human placental-like alkaline phosphatase gene and mechanisms involved in its induction by sodium butyrate.
Topics: Alkaline Phosphatase; Amino Acid Sequence; Butyrates; Butyric Acid; Chloramphenicol O-Acetyltransfer | 1992 |
Influence of butyrate on lipid metabolism, survival, and differentiation of colon cancer cells.
Topics: Adenocarcinoma; Butyrates; Butyric Acid; Cell Count; Cell Differentiation; Cell Survival; Colonic Ne | 1991 |
Increased cell surface EGF receptor expression during the butyrate-induced differentiation of human HCT-116 colon tumor cell clones.
Topics: Alkaline Phosphatase; beta-Galactosidase; Butyrates; Butyric Acid; Cell Differentiation; Cell Divisi | 1990 |
Role of the extracellular matrix on the growth and differentiated phenotype of murine colonic adenocarcinoma cells in vitro.
Topics: Adenocarcinoma; Alkaline Phosphatase; Animals; Butyrates; Butyric Acid; Cell Differentiation; Coloni | 1991 |
Modulation of EGF receptor expression by differentiating agents in human colon carcinoma cell lines.
Topics: Alkaline Phosphatase; Blotting, Northern; Butyrates; Butyric Acid; Cell Differentiation; Cell Divisi | 1990 |
Effects of 1,25-dihydroxyvitamin D3 and its analogs on butyrate-induced differentiation of HT-29 human colonic carcinoma cells and on the reversal of the differentiated phenotype.
Topics: Butyrates; Butyric Acid; Calcitriol; Cell Differentiation; Cell Line; Colonic Neoplasms; Humans; Kin | 1990 |
Differential effects of sodium butyrate and hyperosmolality on the modulation of alkaline phosphatases of LoVo cells.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Carcinoma; Child; Colonic Neoplasms; Humans; Osmolar | 1990 |
Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence.
Topics: Adenoma; Animals; Butyrates; Butyric Acid; Carcinoma; Cell Division; Cell Line; Cell Transformation, | 1990 |
Effects of nucleoside analogs and sodium butyrate on recovery from potentially lethal X ray damage in human colon tumor cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Azacitidine; Butyrates; Butyric Acid; Cells, Cultured; Colon; | 1987 |
Modulation of carcinoembryonic antigen release by HT-29 colon carcinoma line in the presence of different agents.
Topics: Acetamides; Azacitidine; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Differentiation; Co | 1987 |
Alterations in the expression of pp60c-src and p56lck associated with butyrate-induced differentiation of human colon carcinoma cells.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Carcinoma; Cell Differentiation; Colonic Neoplasms; G | 1989 |
Intestinal alkaline phosphatase is secreted bidirectionally from villous enterocytes.
Topics: Adenocarcinoma; Alkaline Phosphatase; Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell L | 1989 |
Modulation of the expression of a multidrug resistance gene (mdr-1/P-glycoprotein) by differentiating agents.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood Proteins; Butyrates; Butyric Acid; Ce | 1989 |
Heterogeneity in the induction and expression of carcinoembryonic antigen-related antigens in human colon cancer cell lines.
Topics: Adenocarcinoma; Blotting, Northern; Blotting, Southern; Blotting, Western; Butyrates; Butyric Acid; | 1989 |
Effect of human serum on alkaline phosphatase induction in cultured human tumor cells.
Topics: Acid Phosphatase; Alkaline Phosphatase; Blood; Butyrates; Butyric Acid; Colonic Neoplasms; Enzyme In | 1989 |
Modulation of alkaline phosphatases in LoVo, a human colon carcinoma cell line.
Topics: Alkaline Phosphatase; Bone and Bones; Butyrates; Butyric Acid; Colonic Neoplasms; Cycloheximide; Enz | 1989 |
Antibody-mediated targeting of differentiation inducers to tumor cells: inhibition of colonic cancer cell growth in vitro and in vivo. A preliminary note.
Topics: Adenocarcinoma; Animals; Antibodies, Monoclonal; Butyrates; Butyric Acid; Cell Differentiation; Cell | 1989 |
Modification of Ha-ras oncogene p21 expression and cell cycle progression in the human colonic cancer cell line HT-29.
Topics: Butyrates; Butyric Acid; Cell Cycle; Cell Line; Colonic Neoplasms; DNA, Neoplasm; Flow Cytometry; Ge | 1987 |
Potentiation of X ray sensitivity by combinations of sodium butyrate and buthionine sulfoximine.
Topics: Buthionine Sulfoximine; Butyrates; Butyric Acid; Cell Line; Cell Survival; Colonic Neoplasms; Combin | 1988 |
Comparison of the tyrosine kinase activity with the proliferation rate in human colon solid tumors and tumor cell lines.
Topics: Butyrates; Butyric Acid; Cell Division; Colonic Neoplasms; Humans; Interphase; Protein-Tyrosine Kina | 1988 |
Effects of short-chain fatty acids on a human colon carcinoma cell line.
Topics: Adult; Alkaline Phosphatase; Antigens, Neoplasm; Butyrates; Butyric Acid; Carcinoembryonic Antigen; | 1988 |
Expression of carcinoembryonic antigen by adenoma and carcinoma derived epithelial cell lines: possible marker of tumour progression and modulation of expression by sodium butyrate.
Topics: Adenoma; Biomarkers, Tumor; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Carcinoma; Colonic Ne | 1988 |
The effect of sodium butyrate and retinoic acid on growth and CEA production in a series of human colorectal tumor cell lines representing different states of differentiation.
Topics: Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Adhesion; Cell Division; Cell Line; Colonic | 1988 |
Modification of the hypoxic fraction of a xenografted human colon tumor by differentiation-inducing agents.
Topics: Animals; Butyrates; Butyric Acid; Cell Differentiation; Cell Survival; Colonic Neoplasms; Female; Fo | 1988 |
Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate.
Topics: Buthionine Sulfoximine; Butyrates; Butyric Acid; Cell Line; Cell Survival; Colonic Neoplasms; DNA Re | 1988 |
Contrasting effects of the differentiating agent sodium butyrate on recovery processes after x-irradiation in heterogeneous human colon tumor cells.
Topics: Adenocarcinoma; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Cell Surviv | 1986 |
Effects of differing concentrations of sodium butyrate on 1,2-dimethylhydrazine-induced rat intestinal neoplasia.
Topics: Animals; Butyrates; Butyric Acid; Colonic Neoplasms; Dimethylhydrazines; Intestinal Neoplasms; Intes | 1986 |
Effects of sodium butyrate on human colonic adenocarcinoma cells. Induction of placental-like alkaline phosphatase.
Topics: Adenocarcinoma; Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Colo | 1987 |
Effect of growth and sodium butyrate on brush border membrane-associated hydrolases in human colorectal cancer cell lines.
Topics: Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Colonic Neoplasms; D | 1985 |
Polar solvent-induced changes in membrane lipid lateral diffusion in human colon cancer cells.
Topics: Butyrates; Butyric Acid; Cell Line; Colonic Neoplasms; Diffusion; Dimethyl Sulfoxide; Dimethylformam | 1985 |
Enhancement of radiation injury in human colon tumor cells by the maturational agent sodium butyrate (NaB).
Topics: Adenocarcinoma; Butyrates; Butyric Acid; Cell Line; Cell Survival; Colonic Neoplasms; Dose-Response | 1985 |