butyric acid has been researched along with Colonic Diverticulosis in 1 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Krokowicz, L | 1 |
| Stojcev, Z | 1 |
| Kaczmarek, BF | 1 |
| Kociemba, W | 1 |
| Kaczmarek, E | 1 |
| Walkowiak, J | 1 |
| Krokowicz, P | 1 |
| Drews, M | 1 |
| Banasiewicz, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Gut Butyrate Delivery on Blood Pressure in African Americans With Hypertension[NCT04415333] | Phase 1 | 20 participants (Actual) | Interventional | 2021-07-08 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Blood biomarker samples were collected for the inflammatory cytokine IL-1β. (NCT04415333)
Timeframe: up to 1 hour post enema
| Intervention | pg/mL (Mean) |
|---|---|
| Sodium Butyrate [5 mmol] | NA |
| Sodium Butyrate [80 mmol] | NA |
| Control | NA |
Immediately following self-administration of butyrate enema, participants will be fitted with an ambulatory blood pressure monitor to be worn for 24 hours. (NCT04415333)
Timeframe: approximately 16 hours post enema
| Intervention | mmHg (Mean) |
|---|---|
| Sodium Butyrate [5 mmol] | 137.5 |
| Sodium Butyrate [80 mmol] | 132.9 |
| Control | 128.2 |
Immediately following self-administration of butyrate enema, participants will be fitted with an ambulatory blood pressure monitor to be worn for 24 hours. (NCT04415333)
Timeframe: approximately 8 hours post enema
| Intervention | mmHg (Mean) |
|---|---|
| Sodium Butyrate [5 mmol] | 123.2 |
| Sodium Butyrate [80 mmol] | 116.2 |
| Control | 114.0 |
Measure blood butyrate concentrations before, 30 minutes post, and 60 minutes post self-administration of the butyrate enemas (NCT04415333)
Timeframe: up to 1 hour post enema
| Intervention | ng/mL (Mean) |
|---|---|
| Baseline | |
| Control | 149.89 |
Measure blood butyrate concentrations before, 30 minutes post, and 60 minutes post self-administration of the butyrate enemas (NCT04415333)
Timeframe: up to 1 hour post enema
| Intervention | ng/mL (Mean) | |
|---|---|---|
| Baseline | 30 Minutes Post | |
| Sodium Butyrate [5 mmol] | 143.88 | 138.64 |
| Sodium Butyrate [80 mmol] | 138.60 | 151.57 |
1 trial available for butyric acid and Colonic Diverticulosis
| Article | Year |
|---|---|
Microencapsulated sodium butyrate administered to patients with diverticulosis decreases incidence of diverticulitis--a prospective randomized study.
Topics: Butyric Acid; Capsules; Diverticulitis, Colonic; Diverticulosis, Colonic; Double-Blind Method; Femal | 2014 |