butyric acid has been researched along with Chromosomal Translocation in 4 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To use NB4, an authentic human acute promyelocytic leukemia cell line, as well as the marrow cells from patients with acute promyelocytic leukemia (APL), containing the PML/RAR alpha fusion gene and fused protein to examine the growth inhibition and cytodifferentiation induced by all-trans retinoic acid (ATRA), butyric acid (BA) and its prodrug tributyrin (TB) either as a single agent or in combinations." | 7.70 | Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells. ( Chen, L; Chen, Z; Pan, J; Wang, W; Xue, Y, 1999) |
| "To use NB4, an authentic human acute promyelocytic leukemia cell line, as well as the marrow cells from patients with acute promyelocytic leukemia (APL), containing the PML/RAR alpha fusion gene and fused protein to examine the growth inhibition and cytodifferentiation induced by all-trans retinoic acid (ATRA), butyric acid (BA) and its prodrug tributyrin (TB) either as a single agent or in combinations." | 3.70 | Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells. ( Chen, L; Chen, Z; Pan, J; Wang, W; Xue, Y, 1999) |
| "De-regulation of c-myc by chromosomal translocation is one crucial step for the development of Burkitt's lymphoma." | 1.29 | Among 17 inducers of differentiation only sodium butyrate causes a permanent down-regulation of c-myc in Burkitt's lymphoma. ( Bornkamm, GW; Polack, A; Rottleb, C, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rottleb, C | 1 |
| Bornkamm, GW | 1 |
| Polack, A | 1 |
| Alexandrov, I | 1 |
| Romanova, L | 1 |
| Mushinski, F | 1 |
| Nordan, R | 1 |
| Niitsu, N | 1 |
| Hayashi, Y | 1 |
| Honma, Y | 1 |
| Chen, Z | 1 |
| Wang, W | 1 |
| Pan, J | 1 |
| Chen, L | 1 |
| Xue, Y | 1 |
4 other studies available for butyric acid and Chromosomal Translocation
| Article | Year |
|---|---|
Among 17 inducers of differentiation only sodium butyrate causes a permanent down-regulation of c-myc in Burkitt's lymphoma.
Topics: Alleles; Burkitt Lymphoma; Butyrates; Butyric Acid; Cell Differentiation; Down-Regulation; Gene Expr | 1995 |
Sodium butyrate suppresses apoptosis in human Burkitt lymphomas and murine plasmacytomas bearing c-myc translocations.
Topics: Animals; Apoptosis; Burkitt Lymphoma; Butyrates; Butyric Acid; Genes, myc; Histamine Antagonists; Hu | 1998 |
Downregulation of MLL-CBP fusion gene expression is associated with differentiation of SN-1 cells with t(11;16)(q23;p13).
Topics: Alitretinoin; Antineoplastic Agents; Artificial Gene Fusion; Butyric Acid; Calcitriol; Cell Differen | 2001 |
Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells.
Topics: Butyric Acid; Cell Transformation, Neoplastic; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; | 1999 |