butyric acid has been researched along with Cell Transformation, Neoplastic in 28 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To use NB4, an authentic human acute promyelocytic leukemia cell line, as well as the marrow cells from patients with acute promyelocytic leukemia (APL), containing the PML/RAR alpha fusion gene and fused protein to examine the growth inhibition and cytodifferentiation induced by all-trans retinoic acid (ATRA), butyric acid (BA) and its prodrug tributyrin (TB) either as a single agent or in combinations." | 7.70 | Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells. ( Chen, L; Chen, Z; Pan, J; Wang, W; Xue, Y, 1999) |
| "To use NB4, an authentic human acute promyelocytic leukemia cell line, as well as the marrow cells from patients with acute promyelocytic leukemia (APL), containing the PML/RAR alpha fusion gene and fused protein to examine the growth inhibition and cytodifferentiation induced by all-trans retinoic acid (ATRA), butyric acid (BA) and its prodrug tributyrin (TB) either as a single agent or in combinations." | 3.70 | Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells. ( Chen, L; Chen, Z; Pan, J; Wang, W; Xue, Y, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (53.57) | 18.7374 |
| 1990's | 10 (35.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (7.14) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, G | 1 |
| Qin, S | 1 |
| Chen, L | 2 |
| Geng, H | 1 |
| Zheng, Y | 1 |
| Xia, C | 1 |
| Yao, J | 1 |
| Deng, L | 1 |
| Astakhova, L | 1 |
| Ngara, M | 1 |
| Babich, O | 1 |
| Prosekov, A | 1 |
| Asyakina, L | 1 |
| Dyshlyuk, L | 1 |
| Midtvedt, T | 1 |
| Zhou, X | 1 |
| Ernberg, I | 1 |
| Matskova, L | 1 |
| Trokovic, R | 1 |
| Weltner, J | 1 |
| Manninen, T | 1 |
| Mikkola, M | 1 |
| Lundin, K | 1 |
| Hämäläinen, R | 1 |
| Suomalainen, A | 1 |
| Otonkoski, T | 1 |
| Wintersberger, E | 1 |
| Mudrak, I | 1 |
| Ichikawa, N | 1 |
| Miyashita, T | 1 |
| Nishimune, Y | 1 |
| Matsushiro, A | 1 |
| Zucker, RM | 1 |
| Whittington, K | 1 |
| Price, BJ | 1 |
| Dokhelar, MC | 1 |
| Testa, U | 1 |
| Vainchenker, W | 1 |
| Finale, Y | 1 |
| Tetaud, C | 1 |
| Salem, P | 1 |
| Tursz, T | 1 |
| Schröter, H | 1 |
| Gómez-Lira, MM | 1 |
| Plank, KH | 1 |
| Bode, J | 1 |
| Larsen, JK | 1 |
| Christensen, IJ | 1 |
| Kieler, J | 1 |
| Gossett, RE | 1 |
| Schroeder, F | 1 |
| Gunn, JM | 1 |
| Kier, AB | 1 |
| Chen, Z | 1 |
| Wang, W | 1 |
| Pan, J | 1 |
| Xue, Y | 1 |
| Witte, MM | 1 |
| Parker, RF | 1 |
| Wang, H | 1 |
| Scott, RE | 1 |
| Gopas, J | 1 |
| Ehrlich, T | 1 |
| Cohen, O | 1 |
| Wishniak, O | 1 |
| Tainsky, MA | 1 |
| Segal, S | 1 |
| Rager-Zisman, B | 1 |
| Isakov, N | 1 |
| Orlow, SJ | 1 |
| Chakraborty, AK | 1 |
| Boissy, RE | 1 |
| Pawelek, JM | 1 |
| Tsukamoto, A | 1 |
| Kaneko, Y | 1 |
| Kurokawa, K | 1 |
| Mullins, TD | 1 |
| Kern, HF | 1 |
| Metzgar, RS | 1 |
| Rius, C | 1 |
| Cabañas, C | 1 |
| Aller, P | 1 |
| Williams, AC | 1 |
| Harper, SJ | 1 |
| Paraskeva, C | 1 |
| de Haan, JB | 1 |
| Gevers, W | 1 |
| Parker, MI | 1 |
| Schmidt, R | 1 |
| Cathelineau, C | 1 |
| Cavey, MT | 1 |
| Dionisius, V | 1 |
| Michel, S | 1 |
| Shroot, B | 1 |
| Reichert, U | 1 |
| Stoddart, JH | 1 |
| Lane, MA | 1 |
| Niles, RM | 2 |
| Walker-Jones, D | 1 |
| Valverius, EM | 1 |
| Stampfer, MR | 1 |
| Lippman, ME | 1 |
| Dickson, RB | 1 |
| Bloom, EJ | 1 |
| Siddiqui, B | 1 |
| Hicks, JW | 1 |
| Kim, YS | 1 |
| Xu, K | 1 |
| Li, SD | 1 |
| Xu, DX | 1 |
| Kyritsis, AP | 1 |
| Fletcher, RT | 1 |
| Chader, GJ | 1 |
| Fischkoff, SA | 1 |
| Steinberg, HN | 1 |
| Tsiftsoglou, AS | 1 |
| Robinson, SH | 1 |
1 review available for butyric acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Chemical induction of tumor cell differentiation.
Topics: Animals; Butyrates; Butyric Acid; Cell Division; Cell Line; Cell Transformation, Neoplastic; Choleca | 1985 |
27 other studies available for butyric acid and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Topics: Butyric Acid; Carcinogenesis; Cell Transformation, Neoplastic; Ferroptosis; Humans; Mechanistic Targ | 2023 |
Short Chain Fatty Acids (SCFA) Reprogram Gene Expression in Human Malignant Epithelial and Lymphoid Cells.
Topics: Apoptosis; Butyric Acid; Cell Line, Tumor; Cell Movement; Cell Transformation, Neoplastic; Epithelia | 2016 |
Small molecule inhibitors promote efficient generation of induced pluripotent stem cells from human skeletal myoblasts.
Topics: Adult; Animals; Antigens, Differentiation; Benzamides; Butyric Acid; Cell Culture Techniques; Cell T | 2013 |
Sodium butyrate inhibits the synthesis of the transformation related protein p 53 in 3T6 mouse fibroblasts.
Topics: Animals; Antibodies, Monoclonal; Butyrates; Butyric Acid; Cell Line; Cell Transformation, Neoplastic | 1984 |
Production, purification and characterization of the plasminogen activator in teratocarcinoma stem cells induced with sodium butyrate.
Topics: Animals; Butyrates; Butyric Acid; Cell Line; Cell Transformation, Neoplastic; Electrophoresis, Polya | 1984 |
Differentiation of HL-60 cells: cell volume and cell cycle changes.
Topics: Butyrates; Butyric Acid; Cell Count; Cell Cycle; Cell Transformation, Neoplastic; Dimethyl Sulfoxide | 1983 |
NK cell sensitivity of the leukemic K 562 cells; effect of sodium butyrate and hemin induction.
Topics: Animals; Binding, Competitive; Butyrates; Butyric Acid; Cell Transformation, Neoplastic; Clone Cells | 1982 |
The extent of histone acetylation induced by butyrate and the turnover of acetyl groups depend on the nature of the cell line.
Topics: Acetylation; Animals; Butyrates; Butyric Acid; Carboxylic Acids; Cell Cycle; Cell Line; Cell Transfo | 1981 |
Cell cycle perturbation by sodium butyrate in tumorigenic and non-tumorigenic human urothelial cell lines assessed by flow cytometric bromodeoxyuridine/DNA analysis.
Topics: Amnion; Aneuploidy; Anticarcinogenic Agents; Bromodeoxyuridine; Butyrates; Butyric Acid; Cell Cycle; | 1995 |
Expression of fatty acyl-CoA binding proteins in colon cells: response to butyrate and transformation.
Topics: Actins; Animals; Butyrates; Butyric Acid; Carrier Proteins; Cell Division; Cell Line, Transformed; C | 1997 |
Combination of all-trans retinoic acid with butyric acid and its prodrugs markedly enhancing differentiation of human acute promyelocytic leukemia NB4 cells.
Topics: Butyric Acid; Cell Transformation, Neoplastic; HL-60 Cells; Humans; Leukemia, Promyelocytic, Acute; | 1999 |
Repression of SV40 T oncoprotein expression by DMSO.
Topics: Acetamides; Animals; Antigens, Polyomavirus Transforming; Azacitidine; Blotting, Northern; Blotting, | 1992 |
The H-ras oncogene regulates expression of 70- and 45-kDa cell-surface molecules whose expression correlates with tumor-cell immunogenicity.
Topics: Animals; Antibodies, Monoclonal; Antigens, Surface; Butyrates; Butyric Acid; Cell Line; Cell Transfo | 1992 |
Inhibition of induced melanogenesis in Cloudman melanoma cells by four phenotypic modifiers.
Topics: 1-Methyl-3-isobutylxanthine; Acetamides; Animals; Butyrates; Butyric Acid; Cell Transformation, Neop | 1990 |
Novobiocin modulates cytokeratin assembly and differentiation of human hepatoma cells induced by butyrate and teleocidin.
Topics: Acetylation; Butyrates; Butyric Acid; Carcinogens; Carcinoma, Hepatocellular; Cell Transformation, N | 1991 |
Ultrastructural differentiation of sodium butyrate-treated human pancreatic adenocarcinoma cell lines.
Topics: Adenocarcinoma; Alkaline Phosphatase; Butyrates; Butyric Acid; Cell Division; Cell Transformation, N | 1991 |
The induction of vimentin gene expression by sodium butyrate in human promonocytic leukemia U937 cells.
Topics: Butyrates; Butyric Acid; Cell Transformation, Neoplastic; Cycloheximide; Gene Expression Regulation, | 1990 |
Neoplastic transformation of a human colonic epithelial cell line: in vitro evidence for the adenoma to carcinoma sequence.
Topics: Adenoma; Animals; Butyrates; Butyric Acid; Carcinoma; Cell Division; Cell Line; Cell Transformation, | 1990 |
Effects of sodium butyrate on the synthesis and methylation of DNA in normal cells and their transformed counterparts.
Topics: Butyrates; Butyric Acid; Cell Line; Cell Survival; Cell Transformation, Neoplastic; DNA; DNA, Neopla | 1986 |
Sodium butyrate selectively antagonizes the inhibitory effect of retinoids on cornified envelope formation in cultured human keratinocytes.
Topics: Butyrates; Butyric Acid; Carrier Proteins; Cell Line, Transformed; Cell Membrane; Cell Transformatio | 1989 |
Sodium butyrate suppresses the transforming activity of an activated N-ras oncogene in human colon carcinoma cells.
Topics: Butyrates; Butyric Acid; Cell Differentiation; Cell Transformation, Neoplastic; DNA, Neoplasm; Gene | 1989 |
Stimulation of epithelial membrane antigen expression by transforming growth factor-beta in normal and oncogene-transformed human mammary epithelial cells.
Topics: Antibodies, Monoclonal; Antigens, Neoplasm; Butyrates; Butyric Acid; Cell Line; Cell Transformation, | 1989 |
Effect of sodium butyrate, a differentiating agent, on cell surface glycoconjugates of a human pancreatic cell line.
Topics: Butyrates; Butyric Acid; Cell Division; Cell Line; Cell Membrane; Cell Transformation, Neoplastic; G | 1989 |
[Studies on cell surface fibronectin of transformed Syrian hamster lung cells induced by butyric acid].
Topics: Animals; Butyrates; Butyric Acid; Cell Line; Cell Transformation, Neoplastic; Chromatography, Affini | 1989 |
Laminin: an initiating role in retinoblastoma cell attachment and differentiation.
Topics: Antibodies; Bucladesine; Butyrates; Butyric Acid; Cell Adhesion; Cell Line; Cell Transformation, Neo | 1986 |
Graded increase in probability of eosinophilic differentiation of HL-60 promyelocytic leukemia cells induced by culture under alkaline conditions.
Topics: Agar; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cul | 1988 |
Loss of suppression of normal bone marrow colony formation by leukemic cell lines after differentiation is induced by chemical agents.
Topics: Animals; Bone Marrow; Butyrates; Butyric Acid; Cell Differentiation; Cell Line; Cell Transformation, | 1985 |