butyric acid has been researched along with Cardiomegaly in 2 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present work is aimed to investigate the effect of NaBu on angiotensin II (Ang II)-induced cardiac hypertrophy and the underlying mechanism in in vivo and in vitro models." | 7.91 | Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6-dependent mechanism. ( Boini, KM; Chen, Y; Deng, M; Lu, A; Tan, Z; Wang, L; Wu, C; Yang, T; Zhang, L; Zhu, Q, 2019) |
| " The present work is aimed to investigate the effect of NaBu on angiotensin II (Ang II)-induced cardiac hypertrophy and the underlying mechanism in in vivo and in vitro models." | 3.91 | Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6-dependent mechanism. ( Boini, KM; Chen, Y; Deng, M; Lu, A; Tan, Z; Wang, L; Wu, C; Yang, T; Zhang, L; Zhu, Q, 2019) |
| "Likewise, HDAC inhibition attenuates cardiac hypertrophy, as evidenced by a reduced heart/tibia ratio and areas of cardiomyocytes, which is associated with reduced interstitial fibrosis and decreases in active caspase-3 and apoptotic stainings, but also increased angiogenesis in diabetic myocardium." | 1.42 | Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. ( Chen, Y; Du, J; Lv, G; Qin, G; Zhang, L; Zhao, TC; Zhao, YT; Zhuang, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 2 |
| Deng, M | 1 |
| Lu, A | 1 |
| Chen, Y | 3 |
| Wu, C | 1 |
| Tan, Z | 1 |
| Boini, KM | 1 |
| Yang, T | 1 |
| Zhu, Q | 1 |
| Wang, L | 1 |
| Du, J | 1 |
| Zhao, YT | 1 |
| Lv, G | 1 |
| Zhuang, S | 1 |
| Qin, G | 1 |
| Zhao, TC | 1 |
2 other studies available for butyric acid and Cardiomegaly
| Article | Year |
|---|---|
Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6-dependent mechanism.
Topics: Angiotensin II; Animals; Butyric Acid; Cardiomegaly; Cell Line; Cyclooxygenase 2; Dinoprostone; Gene | 2019 |
Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice.
Topics: Acetylation; Animals; Apoptosis; Butyric Acid; Cardiomegaly; Collagen; Diabetes Mellitus, Experiment | 2015 |