butyric acid has been researched along with Cardiac Hypertrophy in 2 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The present work is aimed to investigate the effect of NaBu on angiotensin II (Ang II)-induced cardiac hypertrophy and the underlying mechanism in in vivo and in vitro models." | 7.91 | Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6-dependent mechanism. ( Boini, KM; Chen, Y; Deng, M; Lu, A; Tan, Z; Wang, L; Wu, C; Yang, T; Zhang, L; Zhu, Q, 2019) |
| " The present work is aimed to investigate the effect of NaBu on angiotensin II (Ang II)-induced cardiac hypertrophy and the underlying mechanism in in vivo and in vitro models." | 3.91 | Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6-dependent mechanism. ( Boini, KM; Chen, Y; Deng, M; Lu, A; Tan, Z; Wang, L; Wu, C; Yang, T; Zhang, L; Zhu, Q, 2019) |
| "Likewise, HDAC inhibition attenuates cardiac hypertrophy, as evidenced by a reduced heart/tibia ratio and areas of cardiomyocytes, which is associated with reduced interstitial fibrosis and decreases in active caspase-3 and apoptotic stainings, but also increased angiogenesis in diabetic myocardium." | 1.42 | Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice. ( Chen, Y; Du, J; Lv, G; Qin, G; Zhang, L; Zhao, TC; Zhao, YT; Zhuang, S, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, L | 2 |
| Deng, M | 1 |
| Lu, A | 1 |
| Chen, Y | 3 |
| Wu, C | 1 |
| Tan, Z | 1 |
| Boini, KM | 1 |
| Yang, T | 1 |
| Zhu, Q | 1 |
| Wang, L | 1 |
| Du, J | 1 |
| Zhao, YT | 1 |
| Lv, G | 1 |
| Zhuang, S | 1 |
| Qin, G | 1 |
| Zhao, TC | 1 |
2 other studies available for butyric acid and Cardiac Hypertrophy
| Article | Year |
|---|---|
Sodium butyrate attenuates angiotensin II-induced cardiac hypertrophy by inhibiting COX2/PGE2 pathway via a HDAC5/HDAC6-dependent mechanism.
Topics: Angiotensin II; Animals; Butyric Acid; Cardiomegaly; Cell Line; Cyclooxygenase 2; Dinoprostone; Gene | 2019 |
Histone deacetylase (HDAC) inhibition improves myocardial function and prevents cardiac remodeling in diabetic mice.
Topics: Acetylation; Animals; Apoptosis; Butyric Acid; Cardiomegaly; Collagen; Diabetes Mellitus, Experiment | 2015 |