butyric acid has been researched along with Carcinogenesis in 8 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Carcinogenesis: The origin, production or development of cancer through genotypic and phenotypic changes which upset the normal balance between cell proliferation and cell death. Carcinogenesis generally requires a constellation of steps, which may occur quickly or over a period of many years.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To understand the various effects of SCFAs on breast carcinogenesis, we investigated the effect of sodium butyrate (NaB) and sodium propionate (NaP) in MCF-7 cell line." | 7.96 | Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7. ( El Boustany, C; El-Hakim, S; Elnar, AA; Ibrahim, JN; Safi, R; Semaan, J, 2020) |
| " Thus, the objective of this study was to kinetically evaluate the antiangiogenic activity of tributyrin (TB), a butyric acid prodrug, in the promotion stage of hepatocarcinogenesis." | 7.91 | Antiangiogenic effects of the chemopreventive agent tributyrin, a butyric acid prodrug, during the promotion phase of hepatocarcinogenesis. ( Andrade, FO; Farsky, SHP; Fernandes, LHG; Furtado, KS; Hebeda, CB; Heidor, R; Horst, MA; Miranda, MLP; Moreno, FS; Sandri, S; Yamamoto, RC, 2019) |
| " Previously, it has been demonstrated that histone deacetylase (HDAC) inhibitor tributyrin, a butyric acid prodrug, to have chemopreventive effects on rat hepatocarcinogenesis." | 7.79 | The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway. ( Beland, FA; de Conti, A; Heidor, R; Koturbash, I; Kuroiwa-Trzmielina, J; Moreno, FS; Ong, TP; Pogribny, IP; Tryndyak, V, 2013) |
| "Quercetin is an important source of free radical scavengers." | 5.91 | Investigation of the combined cytotoxicity induced by sodium butyrate and a flavonoid quercetin treatment on MCF-7 breast cancer cells. ( Aksoy, O; Alimudin, J; Aydin, D; Betts, Z; Deveci Ozkan, A; Yanar, S; Yuksel, B, 2023) |
| "To understand the various effects of SCFAs on breast carcinogenesis, we investigated the effect of sodium butyrate (NaB) and sodium propionate (NaP) in MCF-7 cell line." | 3.96 | Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7. ( El Boustany, C; El-Hakim, S; Elnar, AA; Ibrahim, JN; Safi, R; Semaan, J, 2020) |
| " Thus, the objective of this study was to kinetically evaluate the antiangiogenic activity of tributyrin (TB), a butyric acid prodrug, in the promotion stage of hepatocarcinogenesis." | 3.91 | Antiangiogenic effects of the chemopreventive agent tributyrin, a butyric acid prodrug, during the promotion phase of hepatocarcinogenesis. ( Andrade, FO; Farsky, SHP; Fernandes, LHG; Furtado, KS; Hebeda, CB; Heidor, R; Horst, MA; Miranda, MLP; Moreno, FS; Sandri, S; Yamamoto, RC, 2019) |
| " Previously, it has been demonstrated that histone deacetylase (HDAC) inhibitor tributyrin, a butyric acid prodrug, to have chemopreventive effects on rat hepatocarcinogenesis." | 3.79 | The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway. ( Beland, FA; de Conti, A; Heidor, R; Koturbash, I; Kuroiwa-Trzmielina, J; Moreno, FS; Ong, TP; Pogribny, IP; Tryndyak, V, 2013) |
| "Quercetin is an important source of free radical scavengers." | 1.91 | Investigation of the combined cytotoxicity induced by sodium butyrate and a flavonoid quercetin treatment on MCF-7 breast cancer cells. ( Aksoy, O; Alimudin, J; Aydin, D; Betts, Z; Deveci Ozkan, A; Yanar, S; Yuksel, B, 2023) |
| "Tumorigenesis was not affected by CD166 expression." | 1.39 | CD49f-positive cell population efficiently enriches colon cancer-initiating cells. ( Doki, Y; Haraguchi, N; Hata, T; Ishii, H; Mimori, K; Mizushima, T; Mori, M; Nishimura, J; Ohta, K; Takemasa, I; Uemura, M; Yamamoto, H, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 4 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, G | 1 |
| Qin, S | 1 |
| Chen, L | 1 |
| Geng, H | 1 |
| Zheng, Y | 1 |
| Xia, C | 1 |
| Yao, J | 1 |
| Deng, L | 1 |
| Betts, Z | 1 |
| Deveci Ozkan, A | 1 |
| Yuksel, B | 1 |
| Alimudin, J | 1 |
| Aydin, D | 1 |
| Aksoy, O | 1 |
| Yanar, S | 1 |
| Cacciola, NA | 1 |
| Venneri, T | 1 |
| Salzano, A | 1 |
| D'Onofrio, N | 1 |
| Martano, M | 1 |
| Saggese, A | 1 |
| Vinale, F | 1 |
| Neglia, G | 1 |
| Campanile, C | 1 |
| Baccigalupi, L | 1 |
| Maiolino, P | 1 |
| Cuozzo, M | 1 |
| Russo, R | 1 |
| Balestrieri, ML | 1 |
| D'Occhio, MJ | 1 |
| Ricca, E | 1 |
| Borrelli, F | 1 |
| Campanile, G | 1 |
| Semaan, J | 1 |
| El-Hakim, S | 1 |
| Ibrahim, JN | 1 |
| Safi, R | 1 |
| Elnar, AA | 1 |
| El Boustany, C | 1 |
| Andrade, FO | 1 |
| Furtado, KS | 1 |
| Heidor, R | 2 |
| Sandri, S | 1 |
| Hebeda, CB | 1 |
| Miranda, MLP | 1 |
| Fernandes, LHG | 1 |
| Yamamoto, RC | 1 |
| Horst, MA | 1 |
| Farsky, SHP | 1 |
| Moreno, FS | 2 |
| de Conti, A | 1 |
| Tryndyak, V | 1 |
| Koturbash, I | 1 |
| Kuroiwa-Trzmielina, J | 1 |
| Ong, TP | 1 |
| Beland, FA | 1 |
| Pogribny, IP | 1 |
| Haraguchi, N | 1 |
| Ishii, H | 1 |
| Mimori, K | 1 |
| Ohta, K | 1 |
| Uemura, M | 1 |
| Nishimura, J | 1 |
| Hata, T | 1 |
| Takemasa, I | 1 |
| Mizushima, T | 1 |
| Yamamoto, H | 1 |
| Doki, Y | 1 |
| Mori, M | 1 |
| Tiwari, P | 1 |
| Sahay, S | 1 |
| Pandey, M | 1 |
| Qadri, SS | 1 |
| Gupta, KP | 1 |
8 other studies available for butyric acid and Carcinogenesis
| Article | Year |
|---|---|
Butyrate dictates ferroptosis sensitivity through FFAR2-mTOR signaling.
Topics: Butyric Acid; Carcinogenesis; Cell Transformation, Neoplastic; Ferroptosis; Humans; Mechanistic Targ | 2023 |
Investigation of the combined cytotoxicity induced by sodium butyrate and a flavonoid quercetin treatment on MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Butyric Acid; Carcinogenesis; Carcinogens; Female; Flavonoids; Humans; MCF-7 Cells | 2023 |
Chemopreventive effect of a milk whey by-product derived from Buffalo (Bubalus bubalis) in protecting from colorectal carcinogenesis.
Topics: Animals; Azoxymethane; Buffaloes; Butyric Acid; Carcinogenesis; Colorectal Neoplasms; Humans; Mice; | 2023 |
Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7.
Topics: Apoptosis; Breast Neoplasms; Butyric Acid; Carcinogenesis; Cell Cycle; Cell Proliferation; Disease P | 2020 |
Antiangiogenic effects of the chemopreventive agent tributyrin, a butyric acid prodrug, during the promotion phase of hepatocarcinogenesis.
Topics: Actins; Angiogenesis Inhibitors; Animals; Apoptosis; Butyric Acid; Carcinogenesis; Carcinoma, Hepato | 2019 |
The chemopreventive activity of the butyric acid prodrug tributyrin in experimental rat hepatocarcinogenesis is associated with p53 acetylation and activation of the p53 apoptotic signaling pathway.
Topics: Acetylation; Animals; Apoptosis; Butyric Acid; Carcinogenesis; Hepatocytes; Histone Deacetylase Inhi | 2013 |
CD49f-positive cell population efficiently enriches colon cancer-initiating cells.
Topics: AC133 Antigen; Activated-Leukocyte Cell Adhesion Molecule; Animals; Antigens, CD; Biomarkers, Tumor; | 2013 |
Combinatorial chemopreventive effect of butyric acid, nicotinamide and calcium glucarate against the 7,12-dimethylbenz(a)anthracene induced mouse skin tumorigenesis attained by enhancing the induction of intrinsic apoptotic events.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Anticarcinogenic Agents; Apoptosis; Apoptotic Protease-Ac | 2015 |