butyric acid has been researched along with Breast Cancer in 31 studies
Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To understand the various effects of SCFAs on breast carcinogenesis, we investigated the effect of sodium butyrate (NaB) and sodium propionate (NaP) in MCF-7 cell line." | 7.96 | Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7. ( El Boustany, C; El-Hakim, S; Elnar, AA; Ibrahim, JN; Safi, R; Semaan, J, 2020) |
| " In the present work we showed metabolic reprogramming by means of inhibitors of histone deacetylase (HDACis), sodium butyrate and trichostatin A in breast cancer cells representing different stages of aggressiveness and metabolic profile." | 7.81 | Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. ( Amoêdo, ND; Carvalho, É; Pezzuto, P; Rodrigues, MF; Rumjanek, FD, 2015) |
| "Quercetin is an important source of free radical scavengers." | 5.91 | Investigation of the combined cytotoxicity induced by sodium butyrate and a flavonoid quercetin treatment on MCF-7 breast cancer cells. ( Aksoy, O; Alimudin, J; Aydin, D; Betts, Z; Deveci Ozkan, A; Yanar, S; Yuksel, B, 2023) |
| "Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables and sodium butyrate (NaB) is a short-chain fatty acid produced by gut microbiota." | 5.72 | Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition. ( Sharma, M; Tollefsbol, TO, 2022) |
| "We collected faecal samples from 14 breast cancer patients and 14 healthy subjects." | 5.72 | L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis. ( Hu, Y; Li, X; Luo, N; Wu, Y; Zai, H; Zhang, K; Zhang, X; Zhu, Q, 2022) |
| "To understand the various effects of SCFAs on breast carcinogenesis, we investigated the effect of sodium butyrate (NaB) and sodium propionate (NaP) in MCF-7 cell line." | 3.96 | Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7. ( El Boustany, C; El-Hakim, S; Elnar, AA; Ibrahim, JN; Safi, R; Semaan, J, 2020) |
| " In the present work we showed metabolic reprogramming by means of inhibitors of histone deacetylase (HDACis), sodium butyrate and trichostatin A in breast cancer cells representing different stages of aggressiveness and metabolic profile." | 3.81 | Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells. ( Amoêdo, ND; Carvalho, É; Pezzuto, P; Rodrigues, MF; Rumjanek, FD, 2015) |
| " With development of a genomically integrated, ErbB2 promoter-reporting breast cancer cell screen, ErbB2 promoter inhibiting activity was observed by the HDAC inhibitors trichostatin A (TSA) and sodium butyrate." | 3.71 | Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen. ( Benz, CC; Kirk, L; Marden, C; Scott, GK; Xu, F, 2002) |
| "The effects of transforming growth factor beta 1 (TGF-beta1) and sodium butyrate on cell proliferation and the urokinase plasminogen activator (uPA) system were examined in normal human breast epithelial cells (HBECs) and in a breast cancer cell line, MDA-MB-231." | 3.70 | Transforming growth factor beta 1 and sodium butyrate differentially modulate urokinase plasminogen activator and plasminogen activator inhibitor-1 in human breast normal and cancer cells. ( Boilly, B; Dong-Le Bourhis, X; Lambrecht, V, 1998) |
| "The effects of the differentiation inducing agents (DIAS), sodium butyrate (NaBu), retinoic acid (RA), dimethylformamide (DMF), hexamethylene bisacetamide (HMBA), forskolin, and 12-O-tetradecanoylphorbol-13-acetate (TPA), on the growth, morphology, and estrogen receptor (ER) content and epithelial membrane antigen (EMA) expression on a serumless human breast cancer cell line (MCF-7) were compared." | 3.68 | Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells. ( Dupont, MA; Gas, N; Guilbaud, NF; Valette, A, 1990) |
| "Quercetin is an important source of free radical scavengers." | 1.91 | Investigation of the combined cytotoxicity induced by sodium butyrate and a flavonoid quercetin treatment on MCF-7 breast cancer cells. ( Aksoy, O; Alimudin, J; Aydin, D; Betts, Z; Deveci Ozkan, A; Yanar, S; Yuksel, B, 2023) |
| "Sulforaphane (SFN) is an isothiocyanate found in cruciferous vegetables and sodium butyrate (NaB) is a short-chain fatty acid produced by gut microbiota." | 1.72 | Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition. ( Sharma, M; Tollefsbol, TO, 2022) |
| "We collected faecal samples from 14 breast cancer patients and 14 healthy subjects." | 1.72 | L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis. ( Hu, Y; Li, X; Luo, N; Wu, Y; Zai, H; Zhang, K; Zhang, X; Zhu, Q, 2022) |
| "We report that butyrate treatment of breast cancer MCF-7 cells causes a nonreversible growth inhibition by inducing apoptosis in a time- and dose-dependent manner." | 1.29 | Bcl-2 expression regulates sodium butyrate-induced apoptosis in human MCF-7 breast cancer cells. ( Kumar, R; Mandal, M, 1996) |
| "In MCF-7 breast cancer cells, butyrate caused a rapid time- and concentration-dependent decrease in ER mRNA levels, apparent by 3 h at 3 mM butyrate." | 1.28 | Effect of sodium butyrate on estrogen receptor and epidermal growth factor receptor gene expression in human breast cancer cell lines. ( Chiew, YE; deFazio, A; Donoghue, C; Lee, CS; Sutherland, RL, 1992) |
| "Using MCF-7 human breast cancer cells, assay of the rate of PRLR gene transcription by the nuclear run-on technique indicated that 3 mM NaB reduced PRLR gene transcription by 50% after 3 h of treatment and that this effect was maintained for at least 24 h." | 1.28 | Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells. ( de Fazio, A; Kelly, PA; Ormandy, CJ; Sutherland, RL, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (19.35) | 18.7374 |
| 1990's | 14 (45.16) | 18.2507 |
| 2000's | 2 (6.45) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 5 (16.13) | 2.80 |
| Authors | Studies |
|---|---|
| Campbell, CT | 1 |
| Aich, U | 2 |
| Weier, CA | 1 |
| Wang, JJ | 1 |
| Choi, SS | 1 |
| Wen, MM | 1 |
| Maisel, K | 1 |
| Sampathkumar, SG | 1 |
| Yarema, KJ | 2 |
| Sharma, M | 1 |
| Tollefsbol, TO | 1 |
| Zhu, Q | 1 |
| Zai, H | 1 |
| Zhang, K | 1 |
| Zhang, X | 1 |
| Luo, N | 1 |
| Li, X | 1 |
| Hu, Y | 1 |
| Wu, Y | 1 |
| Ujlaki, G | 1 |
| Kovács, T | 1 |
| Vida, A | 1 |
| Kókai, E | 1 |
| Rauch, B | 1 |
| Schwarcz, S | 1 |
| Mikó, E | 1 |
| Janka, E | 1 |
| Sipos, A | 1 |
| Hegedűs, C | 1 |
| Uray, K | 1 |
| Nagy, P | 1 |
| Bai, P | 1 |
| Betts, Z | 1 |
| Deveci Ozkan, A | 1 |
| Yuksel, B | 1 |
| Alimudin, J | 1 |
| Aydin, D | 1 |
| Aksoy, O | 1 |
| Yanar, S | 1 |
| Semaan, J | 1 |
| El-Hakim, S | 1 |
| Ibrahim, JN | 1 |
| Safi, R | 1 |
| Elnar, AA | 1 |
| El Boustany, C | 1 |
| Nakagawa, H | 1 |
| Yui, Y | 1 |
| Sasagawa, S | 1 |
| Itoh, K | 1 |
| Rodrigues, MF | 1 |
| Carvalho, É | 1 |
| Pezzuto, P | 1 |
| Rumjanek, FD | 1 |
| Amoêdo, ND | 1 |
| Contreras-Leal, E | 1 |
| Hernández-Oliveras, A | 1 |
| Flores-Peredo, L | 1 |
| Zarain-Herzberg, Á | 1 |
| Santiago-García, J | 1 |
| Almaraz, RT | 1 |
| Khanna, HS | 1 |
| Tan, E | 1 |
| Bhattacharya, R | 1 |
| Shah, S | 1 |
| Scott, GK | 1 |
| Marden, C | 1 |
| Xu, F | 1 |
| Kirk, L | 1 |
| Benz, CC | 1 |
| Abe, M | 2 |
| Kufe, DW | 2 |
| Stevens, MS | 1 |
| Aliabadi, Z | 1 |
| Moore, MR | 1 |
| Sheikh, MS | 1 |
| Shao, ZM | 1 |
| Chen, JC | 1 |
| Li, XS | 1 |
| Hussain, A | 1 |
| Fontana, JA | 1 |
| Keane, MM | 1 |
| Lowrey, GA | 1 |
| Ettenberg, SA | 1 |
| Dayton, MA | 1 |
| Lipkowitz, S | 1 |
| Mandal, M | 1 |
| Kumar, R | 1 |
| Li, S | 1 |
| Ke, S | 1 |
| Budde, RJ | 1 |
| Dong-Le Bourhis, X | 1 |
| Lambrecht, V | 1 |
| Boilly, B | 1 |
| Kondo, K | 1 |
| Kohno, N | 1 |
| Yokoyama, A | 1 |
| Hiwada, K | 1 |
| Soldatenkov, VA | 1 |
| Prasad, S | 1 |
| Voloshin, Y | 1 |
| Dritschilo, A | 1 |
| Perey, L | 1 |
| Hayes, DF | 1 |
| Kufe, D | 1 |
| Kato, M | 1 |
| Brijlall, D | 1 |
| Adler, SA | 1 |
| Kato, S | 1 |
| Herz, F | 1 |
| deFazio, A | 1 |
| Chiew, YE | 1 |
| Donoghue, C | 1 |
| Lee, CS | 1 |
| Sutherland, RL | 3 |
| Ormandy, CJ | 2 |
| de Fazio, A | 2 |
| Kelly, PA | 2 |
| Järvinen, M | 1 |
| Andersson, LC | 1 |
| Virtanen, I | 1 |
| Guilbaud, NF | 1 |
| Gas, N | 1 |
| Dupont, MA | 1 |
| Valette, A | 1 |
| Resnicoff, M | 1 |
| Medrano, EE | 1 |
| Wasserman, L | 1 |
| Nordenberg, J | 1 |
| Beery, E | 1 |
| Deutsch, AA | 1 |
| Novogrodsky, A | 1 |
| Graham, KA | 1 |
| Buick, RN | 1 |
31 other studies available for butyric acid and Breast Cancer
| Article | Year |
|---|---|
Targeting pro-invasive oncogenes with short chain fatty acid-hexosamine analogues inhibits the mobility of metastatic MDA-MB-231 breast cancer cells.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Drug Design; E | 2008 |
Combinatorial epigenetic mechanisms of sulforaphane, genistein and sodium butyrate in breast cancer inhibition.
Topics: Apoptosis; Breast Neoplasms; Butyric Acid; Cell Line, Tumor; Epigenesis, Genetic; Female; Genistein; | 2022 |
L-norvaline affects the proliferation of breast cancer cells based on the microbiome and metabolome analysis.
Topics: Breast Neoplasms; Butyric Acid; Cell Proliferation; Feces; Female; Gastrointestinal Microbiome; Guai | 2022 |
Identification of Bacterial Metabolites Modulating Breast Cancer Cell Proliferation and Epithelial-Mesenchymal Transition.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Butyric Acid; Cell Line, Tumor; Cell Proliferation | 2023 |
Investigation of the combined cytotoxicity induced by sodium butyrate and a flavonoid quercetin treatment on MCF-7 breast cancer cells.
Topics: Breast Neoplasms; Butyric Acid; Carcinogenesis; Carcinogens; Female; Flavonoids; Humans; MCF-7 Cells | 2023 |
Comparative effect of sodium butyrate and sodium propionate on proliferation, cell cycle and apoptosis in human breast cancer cells MCF-7.
Topics: Apoptosis; Breast Neoplasms; Butyric Acid; Carcinogenesis; Cell Cycle; Cell Proliferation; Disease P | 2020 |
Evidence for intrathecal sodium butyrate as a novel option for leptomeningeal metastasis.
Topics: Animals; Antineoplastic Agents; Astrocytes; Brain; Breast Neoplasms; Butyric Acid; Cell Line, Tumor; | 2018 |
Reciprocal modulation of histone deacetylase inhibitors sodium butyrate and trichostatin A on the energy metabolism of breast cancer cells.
Topics: Breast Neoplasms; Butyric Acid; Cell Line, Tumor; Energy Metabolism; Glycolysis; Histone Deacetylase | 2015 |
Histone deacetylase inhibitors promote the expression of ATP2A3 gene in breast cancer cell lines.
Topics: Breast Neoplasms; Butyric Acid; Cell Line, Tumor; CpG Islands; DNA Methylation; Female; Gene Express | 2016 |
Metabolic oligosaccharide engineering with N-Acyl functionalized ManNAc analogs: cytotoxicity, metabolic flux, and glycan-display considerations.
Topics: Acylation; Adenocarcinoma; Animals; Antineoplastic Agents; Apoptosis; Azides; Breast Neoplasms; Buty | 2012 |
Transcriptional repression of ErbB2 by histone deacetylase inhibitors detected by a genomically integrated ErbB2 promoter-reporting cell screen.
Topics: Blotting, Western; Breast Neoplasms; Butyric Acid; Cell Survival; Deoxyribonuclease I; DNA Probes; D | 2002 |
Sodium butyrate induction of milk-related antigens in human MCF-7 breast carcinoma cells.
Topics: Antibodies, Monoclonal; Antigens, Surface; Breast Neoplasms; Butyrates; Butyric Acid; Cell Division; | 1984 |
Effect of sodium butyrate on human breast carcinoma (MCF-7) cellular proliferation, morphology, and CEA production.
Topics: Breast Neoplasms; Butyrates; Butyric Acid; Carcinoembryonic Antigen; Cell Division; Cell Line; Femal | 1984 |
Associated effects of sodium butyrate on histone acetylation and estrogen receptor in the human breast cancer cell line MCF-7.
Topics: Acetylation; Breast Neoplasms; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Cytoplasm; Female; | 1984 |
Expression of estrogen receptors in estrogen receptor-negative human breast carcinoma cells: modulation of epidermal growth factor-receptor (EGF-R) and transforming growth factor alpha (TGF alpha) gene expression.
Topics: Breast Neoplasms; Butyrates; Butyric Acid; Carcinoma; Clone Cells; Down-Regulation; ErbB Receptors; | 1994 |
The protein tyrosine phosphatase DEP-1 is induced during differentiation and inhibits growth of breast cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; | 1996 |
Bcl-2 expression regulates sodium butyrate-induced apoptosis in human MCF-7 breast cancer cells.
Topics: Apoptosis; Breast Neoplasms; Butyrates; Butyric Acid; Carcinoma; Cell Division; Down-Regulation; Hum | 1996 |
The C-terminal Src kinase (Csk) is widely expressed, active in HT-29 cells that contain activated Src, and its expression is downregulated in butyrate-treated SW620 cells.
Topics: Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Colonic Neoplasms; CSK Tyrosine-Pro | 1996 |
Transforming growth factor beta 1 and sodium butyrate differentially modulate urokinase plasminogen activator and plasminogen activator inhibitor-1 in human breast normal and cancer cells.
Topics: Breast; Breast Neoplasms; Butyrates; Butyric Acid; Cell Division; Epithelial Cells; Female; Humans; | 1998 |
Decreased MUC1 expression induces E-cadherin-mediated cell adhesion of breast cancer cell lines.
Topics: alpha Catenin; beta Catenin; Blotting, Northern; Breast Neoplasms; Butyrates; Butyric Acid; Cadherin | 1998 |
Sodium butyrate induces apoptosis and accumulation of ubiquitinated proteins in human breast carcinoma cells.
Topics: Apoptosis; Breast Neoplasms; Butyric Acid; DNA Fragmentation; Female; Humans; Immunoblotting; Neopla | 1998 |
Effects of differentiating agents on cell surface expression of the breast carcinoma-associated DF3-P epitope.
Topics: Antigens, Neoplasm; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Epitopes; Flow | 1992 |
Effect of hyperosmolality on alkaline phosphatase and stress-response protein 27 of MCF-7 breast cancer cells.
Topics: Alkaline Phosphatase; Breast Neoplasms; Butyrates; Butyric Acid; Carcinoma; Female; Heat-Shock Prote | 1992 |
Effect of sodium butyrate on estrogen receptor and epidermal growth factor receptor gene expression in human breast cancer cell lines.
Topics: Breast Neoplasms; Butyrates; Butyric Acid; Cell Line; Cell Nucleus; Cycloheximide; DNA Probes; ErbB | 1992 |
Transcriptional regulation of prolactin receptor gene expression by sodium butyrate in MCF-7 human breast cancer cells.
Topics: Blotting, Northern; Breast Neoplasms; Butyrates; Butyric Acid; Cycloheximide; Dactinomycin; Gene Exp | 1992 |
K562 erythroleukemia cells express cytokeratins 8, 18, and 19 and epithelial membrane antigen that disappear after induced differentiation.
Topics: Blotting, Western; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Epithelial Cells | 1990 |
Coordinate regulation of oestrogen and prolactin receptor expression by sodium butyrate in human breast cancer cells.
Topics: Breast Neoplasms; Butyrates; Butyric Acid; Dose-Response Relationship, Drug; Female; Humans; Kinetic | 1992 |
Effects of differentiation-inducing agents on maturation of human MCF-7 breast cancer cells.
Topics: Acetamides; Antigens, Neoplasm; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Cel | 1990 |
Growth factors and hormones which affect survival, growth, and differentiation of the MCF-7 stem cells and their descendants.
Topics: Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Survival; Cultu | 1989 |
Differential effects of sodium butyrate and dimethylsulfoxide on gamma-glutamyl transpeptidase and alkaline phosphatase activities in MCF-7 breast cancer cells.
Topics: Alkaline Phosphatase; Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Cell Division | 1987 |
Sodium butyrate induces differentiation in breast cancer cell lines expressing the estrogen receptor.
Topics: Breast Neoplasms; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Humans; M | 1988 |