Page last updated: 2024-10-16

butyric acid and Autoimmune Diabetes

butyric acid has been researched along with Autoimmune Diabetes in 6 studies

Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.

Research Excerpts

ExcerptRelevanceReference
"The pathophysiology of type 1 diabetes has been linked to altered gut microbiota and more specifically to a shortage of intestinal production of the short-chain fatty acid (SCFA) butyrate, which may play key roles in maintaining intestinal epithelial integrity and in human and gut microbial metabolism."2.94Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial. ( Bekkering, S; Berkvens, A; Bindraban, R; Dallinga-Thie, GM; Davids, M; de Groot, PF; Duinkerken, G; Herrema, H; Hoekstra, JBL; Holleman, F; Hutten, B; Imangaliyev, S; Keij, FM; Kemper, EM; Kroon, J; Levels, JHM; Levin, E; Netea, M; Nieuwdorp, M; Nikolic, T; Roep, BO; Simsek, S; Stroes, ESG; van Hoorn, FA; van Raalte, DH; Winkelmeijer, M, 2020)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's4 (66.67)2.80

Authors

AuthorsStudies
Elgamal, DA1
Abou-Elghait, AT1
Ali, AY1
Ali, M1
Bakr, MH1
de Groot, PF1
Nikolic, T1
Imangaliyev, S1
Bekkering, S1
Duinkerken, G1
Keij, FM1
Herrema, H1
Winkelmeijer, M1
Kroon, J1
Levin, E1
Hutten, B1
Kemper, EM1
Simsek, S1
Levels, JHM1
van Hoorn, FA1
Bindraban, R1
Berkvens, A1
Dallinga-Thie, GM1
Davids, M1
Holleman, F1
Hoekstra, JBL1
Stroes, ESG1
Netea, M1
van Raalte, DH1
Roep, BO1
Nieuwdorp, M1
Traisaeng, S1
Batsukh, A1
Chuang, TH1
Herr, DR1
Huang, YF1
Chimeddorj, B1
Huang, CM1
Jacob, N1
Jaiswal, S1
Maheshwari, D1
Nallabelli, N1
Khatri, N1
Bhatia, A1
Bal, A1
Malik, V1
Verma, S1
Kumar, R1
Sachdeva, N1
Endesfelder, D1
Engel, M1
Davis-Richardson, AG1
Ardissone, AN1
Achenbach, P1
Hummel, S1
Winkler, C1
Atkinson, M1
Schatz, D1
Triplett, E1
Ziegler, AG1
zu Castell, W1
Deinhofer, M1
Weissenböck, H1

Trials

1 trial available for butyric acid and Autoimmune Diabetes

ArticleYear
Oral butyrate does not affect innate immunity and islet autoimmunity in individuals with longstanding type 1 diabetes: a randomised controlled trial.
    Diabetologia, 2020, Volume: 63, Issue:3

    Topics: Adaptive Immunity; Administration, Oral; Adult; Autoimmunity; Butyric Acid; Diabetes Mellitus, Type

2020

Other Studies

5 other studies available for butyric acid and Autoimmune Diabetes

ArticleYear
Ultrastructure characterization of pancreatic β-cells is accompanied by modulatory effects of the HDAC inhibitor sodium butyrate on the PI3/AKT insulin signaling pathway in juvenile diabetic rats.
    Molecular and cellular endocrinology, 2020, 03-01, Volume: 503

    Topics: Animals; Butyric Acid; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Glucose; Histone

2020
Leuconostoc mesenteroides fermentation produces butyric acid and mediates Ffar2 to regulate blood glucose and insulin in type 1 diabetic mice.
    Scientific reports, 2020, 05-13, Volume: 10, Issue:1

    Topics: Animals; Blood Glucose; Butyric Acid; Cell Line; Diabetes Mellitus, Experimental; Diabetes Mellitus,

2020
Butyrate induced Tregs are capable of migration from the GALT to the pancreas to restore immunological tolerance during type-1 diabetes.
    Scientific reports, 2020, 11-05, Volume: 10, Issue:1

    Topics: Animals; Butyric Acid; Cell Movement; Diabetes Mellitus, Type 1; Disease Progression; Female; Immune

2020
Towards a functional hypothesis relating anti-islet cell autoimmunity to the dietary impact on microbial communities and butyrate production.
    Microbiome, 2016, Apr-26, Volume: 4

    Topics: Acetic Acid; Adult; Autoantibodies; Autoimmunity; Bacteroides; Breast Feeding; Butyric Acid; Child;

2016
Diagnosis of diabetes mellitus in a bull by means of butyrate infusion.
    Zentralblatt fur Veterinarmedizin. Reihe A, 1998, Volume: 45, Issue:5

    Topics: Animals; Blood Glucose; Butyrates; Butyric Acid; Cattle; Cattle Diseases; Diabetes Mellitus, Type 1;

1998