Page last updated: 2024-10-16

butyric acid and Autism

butyric acid has been researched along with Autism in 5 studies

Butyric Acid: A four carbon acid, CH3CH2CH2COOH, with an unpleasant odor that occurs in butter and animal fat as the glycerol ester.
butyrate : A short-chain fatty acid anion that is the conjugate base of butyric acid, obtained by deprotonation of the carboxy group.
butyric acid : A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.

Research Excerpts

ExcerptRelevanceReference
"We recently showed that prenatal exposure to valproic acid (VPA) in mice causes autism-like behavioral abnormalities, including social interaction deficits, anxiety-like behavior and spatial learning disability, in male offspring."7.80Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. ( Ago, Y; Hara, Y; Hashimoto, H; Hayata-Takano, A; Kataoka, S; Kawanai, T; Maeda, Y; Matsuda, T; Takano, E; Takuma, K; Watanabe, R, 2014)
"Short-chain fatty acids (SCFAs, especially butyric acid) have been demonstrated to play a promising role in the development of autism spectrum disorders (ASD)."4.31Sodium butyrate facilitates CRHR2 expression to alleviate HPA axis hyperactivity in autism-like rats induced by prenatal lipopolysaccharides through histone deacetylase inhibition. ( Chen, J; Li, T; Lin, F; Sun, Z; Wang, X; Yan, J; Yang, T; Ye, S, 2023)
" For the first time, we assessed the synthesis of 5-hydroxytryptamine (5HT) and the metabolic capacity of the 5HT system in the peripheral and central nervous systems (PNS and CNS, respectively) based on tryptophan metabolism based on VPA-induced autism model."4.02Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and sexual maturation. ( Chen, W; Kong, Q; Li, X; Tian, P; Wang, B; Wang, G; Zhang, H; Zhao, J, 2021)
"We recently showed that prenatal exposure to valproic acid (VPA) in mice causes autism-like behavioral abnormalities, including social interaction deficits, anxiety-like behavior and spatial learning disability, in male offspring."3.80Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism. ( Ago, Y; Hara, Y; Hashimoto, H; Hayata-Takano, A; Kataoka, S; Kawanai, T; Maeda, Y; Matsuda, T; Takano, E; Takuma, K; Watanabe, R, 2014)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's4 (80.00)2.80

Authors

AuthorsStudies
Leo, A1
De Caro, C1
Mainardi, P1
Tallarico, M1
Nesci, V1
Marascio, N1
Striano, P1
Russo, E1
Constanti, A1
De Sarro, G1
Citraro, R1
Cristiano, C1
Hoxha, E1
Lippiello, P1
Balbo, I1
Russo, R1
Tempia, F1
Miniaci, MC1
Wang, X1
Sun, Z1
Yang, T1
Lin, F1
Ye, S1
Yan, J1
Li, T1
Chen, J1
Kong, Q1
Wang, B1
Tian, P1
Li, X1
Zhao, J1
Zhang, H1
Chen, W1
Wang, G1
Takuma, K1
Hara, Y1
Kataoka, S1
Kawanai, T1
Maeda, Y1
Watanabe, R1
Takano, E1
Hayata-Takano, A1
Hashimoto, H1
Ago, Y1
Matsuda, T1

Other Studies

5 other studies available for butyric acid and Autism

ArticleYear
Increased efficacy of combining prebiotic and postbiotic in mouse models relevant to autism and depression.
    Neuropharmacology, 2021, 10-15, Volume: 198

    Topics: Animals; Anxiety; Autistic Disorder; Avoidance Learning; Behavior, Animal; Brain-Gut Axis; Butyric A

2021
Maternal treatment with sodium butyrate reduces the development of autism-like traits in mice offspring.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022, Volume: 156

    Topics: Animals; Autism Spectrum Disorder; Autistic Disorder; Behavior, Animal; Butyric Acid; Disease Models

2022
Sodium butyrate facilitates CRHR2 expression to alleviate HPA axis hyperactivity in autism-like rats induced by prenatal lipopolysaccharides through histone deacetylase inhibition.
    mSystems, 2023, 08-31, Volume: 8, Issue:4

    Topics: Animals; Autistic Disorder; Butyric Acid; Corticosterone; Epigenesis, Genetic; Female; Histone Deace

2023
Daily intake of Lactobacillus alleviates autistic-like behaviors by ameliorating the 5-hydroxytryptamine metabolic disorder in VPA-treated rats during weaning and sexual maturation.
    Food & function, 2021, Mar-21, Volume: 12, Issue:6

    Topics: Animals; Autistic Disorder; Behavior, Animal; Butyric Acid; Disease Models, Animal; Fatty Acids, Vol

2021
Chronic treatment with valproic acid or sodium butyrate attenuates novel object recognition deficits and hippocampal dendritic spine loss in a mouse model of autism.
    Pharmacology, biochemistry, and behavior, 2014, Volume: 126

    Topics: Acetylation; Animals; Autistic Disorder; Butyric Acid; CA1 Region, Hippocampal; Dendritic Spines; Di

2014