Compounds > butylhydroxybutylnitrosamine
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butylhydroxybutylnitrosamine and Hyperplasia

butylhydroxybutylnitrosamine has been researched along with Hyperplasia in 68 studies

Research

Studies (68)

TimeframeStudies, this research(%)All Research%
pre-199039 (57.35)18.7374
1990's19 (27.94)18.2507
2000's8 (11.76)29.6817
2010's1 (1.47)24.3611
2020's1 (1.47)2.80

Authors

AuthorsStudies
Akane, H; Cho, YM; Matsushita, K; Morikawa, T; Ogawa, K; Toyoda, T; Yamada, T1
Fukushima, S; Ikegami, M; Mutou, T; Takahashi, H; Wakui, S; Wanibuchi, H1
Hanai, T; Levin, R; Matsumoto, S; Shimizu, N; Uemura, H1
Afonso, J; Arantes-Rodrigues, R; Colaço, A; Da Silva, VM; De La Cruz, LF; Lopes, C; Lourenço, L; Oliveira, PA; Santos, L; Sousa-Diniz, C1
Hirose, M; Imazawa, T; Masegi, T; Nishikawa, A; Okazaki, K; Umemura, T1
Asano, N; Hata, K; Hirose, Y; Iwasaki, T; Kobayashi, H; Kuno, T; Mori, H; Oyama, T; Qiang, SH; Yamada, Y; Zhi, H1
Colaço, A; De la Cruz, LF; Lopes, C; Lopes, P; Oliveira, PA1
Fukushima, S; Ito, N; Koiso, K; Niijima, T; Ohtani, M1
Fukushima, S; Ito, N; Koiso, K; Niijima, T; Ohtani, M; Okamura, T; Sakata, T1
Fukushima, S; Hagiwara, A; Ito, N; Kitaori, M; Shibata, M1
Fukushima, S; Hasegawa, R; Ito, N; Sakata, T; Shirai, T1
Fukushima, S; Hagiwara, A; Imaida, K; Ito, N; Shirai, T1
Fukushima, S; Hirose, M; Inui, M; Ito, N; Sakata, T1
Fukushima, S; Hagiwara, A; Ito, N; Ogiso, T; Shibata, M1
Fukushima, S; Ikawa, E; Ito, N; Kurata, Y; Shibata, M1
Fukushima, S; Imaida, K; Ito, N; Miyata, Y1
Hagiwara, A; Imaida, K; Ito, N; Nakanishi, K; Shibata, M; Tatematsu, M1
Fukushima, S; Hagiwara, A; Ito, N; Nakanishi, K; Tamano, S1
Fukushima, S; Hasegawa, R; Hirose, M; Ito, N; Murasaki, G; Nakanishi, K1
Arai, Y; Fukushima, S; Ito, N; Nishizuka, Y; Ogiso, T1
Babaya, K; Hijioka, T; Hiramatsu, T; Hirao, K; Hirao, Y; Ijuin, M; Ikuma, S; Ohara, S; Ohishi, H; Okajima, E; Shiomi, T1
Fukushima, S; Hirose, M; Imaida, K; Ito, N; Murasaki, G1
Fukushima, S; Hagiwara, A; Ito, N; Nakanishi, K; Shibata, M1
Arai, M; Babaya, K; Fukushima, S; Ito, N; Miyata, Y; Murasaki, G1
Chen, T; Fukushima, S; Kitano, M; Mori, S; Murai, T1
Fukushima, S; Hosono, M; Makino, S; Mori, S; Murai, T; Oohara, T; Takeda, R; Takeuchi, Y1
Jin, L; Takenaka, I; Zhang, XH1
Fukushima, S; Kishimoto, T; Lee, CC; Sugimura, K; Wada, S; Wanibuchi, H; Yamamoto, S1
Doteuchi, M; Fukushima, S; Hosono, M; Makino, S; Mori, S; Murai, T; Oohara, T; Yamashita, H1
Futakuchi, M; Hirose, M; Kimoto, N; Ogawa, K; Sano, M; Shirai, T; Yamaguchi, T1
Chen, TX; Fukushima, S; Kitano, M; Murai, T; Wanibuchi, H; Yamamoto, S1
Sato, D1
Endo, G; Fukushima, S; Li, W; Salim, EI; Wanibuchi, H; Yamamoto, S; Yoshida, K1
Cardoso, PR; Fukushima, S; Padovani, CR; Viana de Camargo, JL; Vieira de Oliveira, S1
Fukushima, S; Ichihara, T; Kishimoto, T; Lee, CC; Sugimura, K; Wada, S; Wanibuchi, H; Yamamoto, S1
Chen, T; Fukushima, S; Lee, CC; Na, Y; Wanibuchi, H; Yamamoto, S1
Fukushima, S; Kim, S; Morimura, K; Salim, EI; Wanibuchi, H; Yamamoto, S; Yano, Y1
Hirose, M; Kawabe, M; Kimoto, N; Miyataka, H; Satoh, T; Shirai, T1
Futakuchi, M; Hirose, M; Iwata, T; Kasai, M; Kimoto, N; Shirai, T1
Hagiwara, A; Ito, N; Kadota, T; Kawabe, M; Maemura, S; Sano, M; Shirai, T; Tamano, S; Tanaka, H; Yanagisawa, T1
Arai, H; Hananouchi, M; Hirose, M; Ito, N; Murasaki, G; Shirai, T1
Kunze, E; Schatt, S; Schauer, A1
Anichkov, NM1
Eliseev, VV; Vlasov, NN1
Friedman, RD; Gaffield, W; Keefer, LK; Reese, DH1
Cohen, SM; Fukushima, S; Ito, N; Shinohara, Y; Shirai, T; Tatematsu, M1
Fukushima, S; Ito, N; Nakanishi, K; Ogiso, T; Shibata, M; Shirai, T1
Hananouchi, M; Hirose, M; Miyata, Y; Mizutani, M; Tatematsu, M1
Fukushima, S; Murasaki, G; Shirai, T; Tatematsu, M; Tsuda, H1
Ito, N1
Fukushima, S; Matsui-Yuasa, I; Otani, S; Shibata, MA; Takada, N; Yano, Y1
Fukuzawa, S; Hashimura, T; Kanamaru, H; Nishio, Y; Yoshida, O; Yu, A1
Bach, PH1
Saito, B1
Kawada, Y; Kobayashi, S; Kuriyama, M; Mori, H; Ohno, T; Takeuchi, T; Tanaka, T; Yamamoto, N1
Frolov, AG; Pliss, GB1
Homma, Y; Oyasu, R; Ozono, S1
Lina, BA; Woutersen, RA1
Mori, H; Mori, Y; Shinoda, T; Tanaka, T; Yoshimi, N1
Aoki, T; Fukushima, S; Inoue, T; Ito, N; Mera, Y; Tatematsu, M1
Okamura, T1
Fukushima, S; Masui, T; Mutai, M; Shirai, T; Takahashi, S1
Akagi, A; Otsuka, H1
Ito, N; Masui, T; Miyata, Y; Nakanishi, K; Shibata, M; Shibata, MA1
Bauer, K; Homma, Y; Oyasu, R; Ozono, S; Samma, S; Wallemark, CB1
Babaya, K; Hirao, Y; Okajima, E; Ozono, S; Sanma, S; Sasaki, K1
Hiasa, Y; Kitahori, Y; Konishi, N; Miyashiro, A; Shimoyama, T1
Fukushima, S; Ito, N; Kurata, Y; Miyata, Y; Ogiso, T; Okuda, M1

Reviews

2 review(s) available for butylhydroxybutylnitrosamine and Hyperplasia

ArticleYear
[Experimental replication of bladder tumors. Morphologic features of early stages of their development].
    Vestnik Akademii meditsinskikh nauk SSSR, 1979, Issue:9

    Topics: 2-Acetylaminofluorene; 2-Naphthylamine; Animals; Butylhydroxybutylnitrosamine; Cell Membrane; Cell Transformation, Neoplastic; DNA, Neoplasm; Epithelium; FANFT; Humans; Hyperplasia; Methylcholanthrene; Methylnitrosourea; Mice; Microscopy, Electron; Naphthalenes; Neoplasms, Experimental; Papilloma; Rats; Schistosoma haematobium; Species Specificity; Sulfonamides; Urinary Bladder Neoplasms

1979
A molecular basis for target-cell toxicity and upper urothelial carcinoma in analgesic abusers and patients with Balkan endemic nephropathy.
    IARC scientific publications, 1991, Issue:115

    Topics: Analgesics; Animals; Balkan Nephropathy; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Carcinogens; Cocarcinogenesis; Disease Models, Animal; Epithelium; Europe; FANFT; Humans; Hyperplasia; Incidence; Kidney Neoplasms; Kidney Papillary Necrosis; Models, Biological; Mycotoxicosis; Ochratoxins; Precancerous Conditions; Rats; Rats, Inbred Strains; Rodentia; Smoking; Substance-Related Disorders; Ureteral Neoplasms

1991

Other Studies

66 other study(ies) available for butylhydroxybutylnitrosamine and Hyperplasia

ArticleYear
Persistent γ-H2AX Formation and Expression of Stem Cell Markers in N-Butyl-N-(4-Hydroxybutyl)Nitrosamine-Induced Bladder Carcinogenesis in Rats.
    Toxicological sciences : an official journal of the Society of Toxicology, 2022, 08-25, Volume: 189, Issue:1

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenesis; Histones; Hyperplasia; Inflammation; Nitrosamines; Phosphoproteins; Rats; Stem Cells; Urinary Bladder; Urinary Bladder Neoplasms

2022
Vascular endothelial growth factor mRNA levels as a biomarker for short-term N-butyl-N-(4-hydroxybutyl) nitrosamine-induced rat bladder carcinogenesis bioassay.
    Journal of applied toxicology : JAT, 2015, Volume: 35, Issue:2

    Topics: Animals; Biological Assay; Biomarkers; Butylhydroxybutylnitrosamine; Carcinogens; Hyperplasia; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A

2015
Bladder outlet obstruction accelerates bladder carcinogenesis.
    BJU international, 2009, Volume: 103, Issue:10

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Female; Fibroblast Growth Factor 2; Hyperplasia; Hypoxia-Inducible Factor 1, alpha Subunit; Muscle, Smooth; Organ Size; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Bladder Neoplasms

2009
The effects of sirolimus on urothelial lesions chemically induced in ICR mice by BBN.
    Anticancer research, 2009, Volume: 29, Issue:8

    Topics: Animals; Antibiotics, Antineoplastic; Butylhydroxybutylnitrosamine; Carcinoma in Situ; Carcinoma, Papillary; Hyperplasia; Immunoenzyme Techniques; Male; Mice; Mice, Inbred ICR; Sirolimus; Urinary Bladder Neoplasms

2009
Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl)nitrosamine in rats after initiation.
    Cancer science, 2003, Volume: 94, Issue:11

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Drug Combinations; Hyperplasia; Isothiocyanates; Male; Organ Size; Rats; Rats, Inbred F344; Risk Factors; Urinary Bladder Neoplasms

2003
Chemoprevention of mouse urinary bladder carcinogenesis by fermented brown rice and rice bran.
    Oncology reports, 2006, Volume: 15, Issue:3

    Topics: Analysis of Variance; Animals; Butylhydroxybutylnitrosamine; Cell Proliferation; Diet; Hyperplasia; Male; Mice; Mice, Inbred ICR; Nucleolus Organizer Region; Oryza; Precancerous Conditions; Silver Staining; Urinary Bladder; Urinary Bladder Neoplasms

2006
E-cadherin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in rats.
    Journal of experimental & clinical cancer research : CR, 2006, Volume: 25, Issue:3

    Topics: Animals; Butylhydroxybutylnitrosamine; Cadherins; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Hyperplasia; Neoplasm Invasiveness; Papilloma; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urothelium

2006
Effects of intravesical instillation of antitumor drugs on the induction of preneoplastic bladder lesions in rats.
    Cancer chemotherapy and pharmacology, 1983, Volume: 11 Suppl

    Topics: Animals; Butylhydroxybutylnitrosamine; Doxorubicin; Female; Hyperplasia; Mitomycin; Mitomycins; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1983
Effects of intravesical instillation of antitumor chemotherapeutic agents on bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Cancer, 1984, Oct-15, Volume: 54, Issue:8

    Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Doxorubicin; Drug Synergism; Female; Hyperplasia; Mitomycin; Mitomycins; Nitrosamines; Papilloma; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1984
Effects of three sweeteners on rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
    Gan, 1984, Volume: 75, Issue:9

    Topics: Animals; Aspartame; Butylhydroxybutylnitrosamine; Diterpenes; Diterpenes, Kaurane; Glucosides; Hyperplasia; Male; Rats; Rats, Inbred F344; Saccharin; Sweetening Agents; Terpenes; Urinary Bladder; Urinary Bladder Neoplasms

1984
Summation and synergism in the promotion of urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)-nitrosamine in F344 rats.
    Gan, 1984, Volume: 75, Issue:11

    Topics: Allopurinol; Animals; Ascorbic Acid; Butylated Hydroxyanisole; Butylhydroxybutylnitrosamine; Drug Synergism; Hyperplasia; Male; Nitrosamines; Rats; Rats, Inbred F344; Saccharin; Tryptophan; Urinary Bladder; Urinary Bladder Neoplasms

1984
Drugs, food additives and natural products as promoters in rat urinary bladder carcinogenesis.
    IARC scientific publications, 1984, Issue:56

    Topics: Animals; Ascorbic Acid; Biphenyl Compounds; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Butylhydroxybutylnitrosamine; Carcinogens; Food Additives; Hyperplasia; Male; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1984
Effect of quercetin on two-stage carcinogenesis of the rat urinary bladder.
    Cancer letters, 1983, Volume: 21, Issue:1

    Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Diet; Flavonoids; Hyperplasia; Male; Nitrosamines; Papilloma; Quercetin; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1983
Promoting effects of various chemicals in rat urinary bladder carcinogenesis initiated by N-nitroso-n-butyl-(4-hydroxybutyl)amine.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 1983, Volume: 21, Issue:1

    Topics: Acetazolamide; Allopurinol; Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Quercetin; Rats; Rats, Inbred F344; Saccharin; Tryptophan; Urinary Bladder; Urinary Bladder Neoplasms

1983
Promotion by ascorbic acid, sodium erythorbate and ethoxyquin of neoplastic lesions in rats initiated with N-butyl-N-(4-hydroxybutyl) nitrosamine.
    Cancer letters, 1984, Volume: 23, Issue:1

    Topics: Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Electrolytes; Ethoxyquin; Hydrogen-Ion Concentration; Hyperplasia; Male; Nitrosamines; Organ Size; Osmolar Concentration; Papilloma; Quinolines; Rats; Urinary Bladder; Urinary Bladder Neoplasms

1984
Promoting effects of unilateral ureteric ligation on two-stage urinary bladder carcinogenesis in rats.
    Cancer letters, 1984, Volume: 23, Issue:3

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Hyperplasia; Kidney; Ligation; Liver; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Ureter; Urinary Bladder Neoplasms

1984
Dose response of saccharin in induction of urinary bladder hyperplasias in Fischer 344 rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Journal of the National Cancer Institute, 1980, Volume: 65, Issue:5

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Dose-Response Relationship, Drug; Female; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms

1980
Organ-specific promoting effects of phenobarbital sodium and sodium saccharin in the induction of liver and urinary bladder tumors in male F344 rats.
    Journal of the National Cancer Institute, 1982, Volume: 68, Issue:3

    Topics: 2-Acetylaminofluorene; Animals; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Hyperplasia; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Organ Specificity; Phenobarbital; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms

1982
Histopathological analysis of preneoplastic changes during N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis in rats.
    Acta pathologica japonica, 1982, Volume: 32, Issue:2

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; Epithelium; Hyperplasia; Kinetics; Male; Nitrosamines; Papilloma; Precancerous Conditions; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms

1982
Enhancing effect of diethylstilbestrol on urinary bladder carcinogenesis in neonatally castrated male rats.
    Gan, 1982, Volume: 73, Issue:6

    Topics: Animals; Animals, Newborn; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Castration; Cocarcinogenesis; Diethylstilbestrol; Hyperplasia; Male; Neoplasms, Experimental; Papilloma; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms

1982
Urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in dogs.
    Cancer research, 1981, Volume: 41, Issue:5

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; Cystoscopy; Dogs; Female; Hematuria; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Papilloma; Urinary Bladder Neoplasms

1981
Effect of cyclophosphamide on rat urinary bladder epithelium treated wtih N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Gan, 1980, Volume: 71, Issue:5

    Topics: Animals; Butylhydroxybutylnitrosamine; Cyclophosphamide; Epithelium; Hyperplasia; Male; Nitrosamines; Rats; Urinary Bladder; Urinary Bladder Neoplasms

1980
Induction of hyperplastic liver nodules by phenobarbital in rats initiated with N-butyl-N-(4-hydroxybutyl) nitrosamine.
    Gan, 1980, Volume: 71, Issue:6

    Topics: Animals; Butylhydroxybutylnitrosamine; Drug Synergism; Hyperplasia; Liver; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Rats

1980
Inhibitory effect of an aromatic retinoic acid analog on urinary bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Gan, 1980, Volume: 71, Issue:3

    Topics: Animals; Butylhydroxybutylnitrosamine; Cricetinae; Etretinate; Hyperplasia; Male; Mice; Nitrosamines; Papilloma; Precancerous Conditions; Rats; Tretinoin; Urinary Bladder; Urinary Bladder Neoplasms

1980
Lack of promoting effects of alpha-linolenic, linoleic or palmitic acid on urinary bladder carcinogenesis in rats.
    Japanese journal of cancer research : Gann, 1995, Volume: 86, Issue:6

    Topics: alpha-Linolenic Acid; Animals; Butylated Hydroxyanisole; Butylhydroxybutylnitrosamine; Hyperplasia; Kidney; Linoleic Acid; Linoleic Acids; Male; Organ Size; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1995
Effect of phenacetin pretreatment on renal pelvic carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine in NON/Shi mice of both sexes.
    Teratogenesis, carcinogenesis, and mutagenesis, 1994, Volume: 14, Issue:4

    Topics: Animals; Butylhydroxybutylnitrosamine; Female; Hydronephrosis; Hyperplasia; Kidney Neoplasms; Kidney Pelvis; Male; Mice; Phenacetin; Sex Factors; Urinary Bladder Neoplasms

1994
Localization of zinc and metallothionein in the rat bladder epithelium during carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
    Urological research, 1996, Volume: 24, Issue:5

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Epithelium; Histocytochemistry; Hyperplasia; Immunohistochemistry; Male; Metallothionein; Neoplasm Invasiveness; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms; Zinc

1996
Cyclin D1 overexpression in rat two-stage bladder carcinogenesis and its relationship with oncogenes, tumor suppressor genes, and cell proliferation.
    Cancer research, 1997, Nov-01, Volume: 57, Issue:21

    Topics: Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cell Nucleus; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Hyperplasia; Male; Neoplasm Proteins; Papilloma; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; RNA, Messenger; Tumor Suppressor Protein p53; Urinary Bladder; Urinary Bladder Neoplasms

1997
F344/Shi rats bearing type b catalase-1 locus are sensitive to sodium L-ascorbate promotion of two-stage urinary bladder carcinogenesis.
    Teratogenesis, carcinogenesis, and mutagenesis, 1998, Volume: 18, Issue:1

    Topics: Alleles; Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Catalase; Disease Susceptibility; Hyperplasia; Male; Neoplasms, Squamous Cell; Papilloma; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms

1998
Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats.
    International journal of cancer, 1998, Aug-31, Volume: 77, Issue:5

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Diet; Diethylnitrosamine; Drug Synergism; Hyperplasia; Isothiocyanates; Liver; Male; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1998
Promotion by sodium L-ascorbate in rat two-stage urinary bladder carcinogenesis is dependent on the interval of administration.
    Japanese journal of cancer research : Gann, 1999, Volume: 90, Issue:1

    Topics: Animals; Ascorbic Acid; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Drug Administration Schedule; Hyperplasia; Male; Papilloma; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1999
Inhibition of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rats by green tea.
    International journal of urology : official journal of the Japanese Urological Association, 1999, Volume: 6, Issue:2

    Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperplasia; Male; Papilloma; Rats; Rats, Wistar; Tea; Urinary Bladder Neoplasms

1999
Promotion of NCI-Black-Reiter male rat bladder carcinogenesis by dimethylarsinic acid an organic arsenic compound.
    Cancer letters, 1998, Dec-11, Volume: 134, Issue:1

    Topics: Alpha-Globulins; Animals; Butylhydroxybutylnitrosamine; Cacodylic Acid; Carcinogenicity Tests; DNA, Neoplasm; Herbicides; Hyperplasia; Immunohistochemistry; Kidney; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms

1998
Effects of uracil calculi on cell growth and apoptosis in the BBN-initiated Wistar rat urinary bladder mucosa.
    Teratogenesis, carcinogenesis, and mutagenesis, 1999, Volume: 19, Issue:4

    Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Cell Division; Hyperplasia; Male; Mucous Membrane; Papilloma; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Uracil; Urinary Bladder; Urinary Bladder Calculi; Urinary Bladder Neoplasms

1999
Reduced expression of the CDK inhibitor p27(KIP1) in rat two-stage bladder carcinogenesis and its association with expression profiles of p21(WAF1/Cip1) and p53.
    Carcinogenesis, 1999, Volume: 20, Issue:9

    Topics: Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Cycle Proteins; Cell Division; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Disease Progression; Gene Expression Regulation, Neoplastic; Genes, p53; Hyperplasia; Male; Microtubule-Associated Proteins; Neoplasm Proteins; Papilloma; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Neoplasm; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Urinary Bladder Neoplasms; Urothelium

1999
Loss of heterozygosity in (LewisxF344)F1 rat urinary bladder tumors induced with N-butyl-N-(4-hydroxybutyl)nitrosamine followed by dimethylarsinic acid or sodium L-ascorbate.
    Japanese journal of cancer research : Gann, 1999, Volume: 90, Issue:8

    Topics: Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Cacodylic Acid; Carcinogenicity Tests; Carcinoma; Hyperplasia; Loss of Heterozygosity; Male; Microsatellite Repeats; Papilloma; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Rats, Inbred Lew; Urinary Bladder; Urinary Bladder Neoplasms

1999
Inhibitory effects of 1,3-diaminopropane, an ornithine decarboxylase inhibitor, on rat two-stage urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Carcinogenesis, 2000, Volume: 21, Issue:2

    Topics: Acetyltransferases; Animals; Anticarcinogenic Agents; Apoptosis; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Cocarcinogenesis; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Diamines; Endothelial Growth Factors; Hydrogen-Ion Concentration; Hyperplasia; Lymphokines; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Polyamines; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2000
Post-initiation effects of a super critical extract of propolis in a rat two-stage carcinogenesis model in female F344 rats.
    Cancer letters, 1999, Dec-01, Volume: 147, Issue:1-2

    Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Administration, Oral; Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Carcinogens; Chemoprevention; Colon; Female; Glutathione Transferase; Hyperplasia; Kidney; Liver; Lung; Mammary Neoplasms, Experimental; Nitrosamines; Organ Size; Propolis; Rats; Rats, Inbred F344; Urinary Bladder

1999
Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats.
    Cancer letters, 2001, Jul-10, Volume: 168, Issue:1

    Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Dietary Supplements; Dose-Response Relationship, Drug; Fatty Acids; Female; Glutathione Transferase; Hyperplasia; Linoleic Acid; Mammary Neoplasms, Experimental; Neoplasms; Nitrosamines; Organ Size; Phosphorylation; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Safflower Oil; Time Factors; Urinary Bladder Neoplasms

2001
Lack of enhancing effect of two Kampo medicines, Sho-saiko-to (TJ-9) and Sairei-to (TJ-114), on rat urinary bladder carcinogenesis initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Teratogenesis, carcinogenesis, and mutagenesis, 2002, Volume: 22, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Butylhydroxybutylnitrosamine; Drugs, Chinese Herbal; Hyperplasia; Male; Papilloma; Rats; Rats, Inbred F344; Steroids; Urinary Bladder; Urinary Bladder Neoplasms

2002
Effect of protease inhibitors in mice treated with the hepatocarcinogen, hexachlorocyclohexane (alpha-isomer) and the bladder carcinogen, N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Gan, 1978, Volume: 69, Issue:4

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Hepatocellular; Hexachlorocyclohexane; Hyperplasia; Leupeptins; Liver; Liver Neoplasms; Mice; Nitrosamines; Pepstatins; Protease Inhibitors; Urinary Bladder Neoplasms

1978
Stages of transformation in the development of N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced transitional cell carcinomas in the urinary bladder of rats.
    Zeitschrift fur Krebsforschung und klinische Onkologie. Cancer research and clinical oncology, 1976, Volume: 87, Issue:2

    Topics: Animals; Autoradiography; Butylhydroxybutylnitrosamine; Carcinoma in Situ; Carcinoma, Papillary; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; DNA, Neoplasm; Female; Hyperplasia; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Urinary Bladder Neoplasms

1976
[Changes in the urinary bladders of rats during experimental carcinogenesis].
    Arkhiv patologii, 1979, Volume: 41, Issue:12

    Topics: Alkaline Phosphatase; Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Female; Glucuronidase; Hyperplasia; Male; Monoamine Oxidase; Oxidoreductases; Papilloma; Rats; Urinary Bladder Neoplasms

1979
Focal suppression and induction of hyperplasia by the bladder carcinogens butyl(4-hydroxybutyl)nitrosamine and buty(3-carboxypropyl)nitrosamine in organ-cultured rat bladder epithelium.
    Journal of the National Cancer Institute, 1978, Volume: 60, Issue:1

    Topics: Animals; Butylhydroxybutylnitrosamine; Cell Division; Epithelium; Hyperplasia; Necrosis; Nitrosamines; Organ Culture Techniques; Propionates; Rats; Urinary Bladder

1978
Neovascularization in benign and malignant urinary bladder epithelial proliferative lesions of the rat observed in situ by scanning electron microscopy and autoradiography.
    Cancer research, 1978, Volume: 38, Issue:6

    Topics: Animals; Autoradiography; Butylhydroxybutylnitrosamine; Cyclophosphamide; Epithelium; Hyperplasia; Male; Microscopy, Electron, Scanning; Neoplasms, Experimental; Rats; Urinary Bladder; Urinary Bladder Neoplasms

1978
Effect of phenacetin and caffeine on the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Gan, 1978, Volume: 69, Issue:3

    Topics: Animals; Butylhydroxybutylnitrosamine; Caffeine; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Papilloma; Phenacetin; Rats; Urinary Bladder Neoplasms

1978
Summation effect of N-butyl-n-(4-hydroxybutyl)nitrosamine, N-(4-(5-nitro-2-furyl)-2-thiazoly)formamide, N-2-fluoroenylacetamide, and 3,3'-dichlorobenzidine on urinary bladder carcinogenesis in rats.
    Gan, 1977, Volume: 68, Issue:2

    Topics: 2-Acetylaminofluorene; 3,3'-Dichlorobenzidine; Animals; Benzidines; Biliary Tract Diseases; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cysts; Fluorenes; Formamides; Hepatic Duct, Common; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Papilloma; Rats; Urinary Bladder; Urinary Bladder Neoplasms

1977
Early surface changes of the urinary bladder epithelium of different animal species induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
    Gan, 1977, Volume: 68, Issue:2

    Topics: Animals; Butylhydroxybutylnitrosamine; Cilia; Cricetinae; Hyperplasia; Male; Mice; Nitrosamines; Papilloma; Rats; Species Specificity; Urinary Bladder; Urinary Bladder Neoplasms

1977
Early changes caused by N-butyl-N-(4-hydroxybutyl)nitrosamine in the bladder epithelium of different animal species.
    Cancer research, 1976, Volume: 36, Issue:7 PT 2

    Topics: Animals; Butylhydroxybutylnitrosamine; Cricetinae; Guinea Pigs; Hyperplasia; Male; Mice; Microscopy, Electron; Neoplasms, Experimental; Precancerous Conditions; Rats; Species Specificity; Urinary Bladder Neoplasms

1976
Spermidine/spermine N1-acetyltransferase, a new biochemical marker for epithelial proliferation in rat bladder.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:10

    Topics: Acetyltransferases; Animals; Biomarkers, Tumor; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Epithelium; G1 Phase; Hyperplasia; Male; Nuclear Proteins; Ornithine Decarboxylase; Papilloma; Polyamines; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; S Phase; Triazines; Urinary Bladder; Urinary Bladder Neoplasms

1992
Anti-promoting effect of nordihydroguaiaretic acid on N-butyl-N-(4-hydroxybutyl)nitrosamine and sodium saccharin-induced rat urinary bladder carcinogenesis.
    Japanese journal of cancer research : Gann, 1992, Volume: 83, Issue:9

    Topics: Animals; Butylhydroxybutylnitrosamine; Hyperplasia; Male; Masoprocol; Papilloma; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder Neoplasms

1992
[A study of BBN induced bladder cancer in mice. The time differences in changes of histopathology and nuclear DNA content].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1991, Volume: 82, Issue:8

    Topics: Animals; Butylhydroxybutylnitrosamine; DNA, Neoplasm; Female; Hyperplasia; Mice; Mice, Inbred C57BL; Paraffin Embedding; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1991
Nucleolar organizer regions in rat urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Virchows Archiv. B, Cell pathology including molecular pathology, 1990, Volume: 58, Issue:5

    Topics: Animals; Butylhydroxybutylnitrosamine; Hyperplasia; Male; Nitrosamines; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred ACI; Urinary Bladder Neoplasms

1990
[Effects of forced diuresis on butylbutanolnitrosamine induction of bladder tumors in rats].
    Voprosy onkologii, 1990, Volume: 36, Issue:1

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; Diuresis; Hyperplasia; Nitrosamines; Papilloma; Rats; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms

1990
Gamma glutamyl transpeptidase activity in rat urothelium treated with bladder carcinogens.
    Cancer letters, 1985, Volume: 29, Issue:1

    Topics: Animals; Animals, Newborn; Butylhydroxybutylnitrosamine; Carcinogens; Female; gamma-Glutamyltransferase; Histocytochemistry; Hyperplasia; Male; Methylnitrosourea; Mucous Membrane; Rats; Staining and Labeling; Time Factors; Urinary Bladder Neoplasms

1985
Effects of urinary potassium and sodium ion concentrations and pH on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in rats.
    Carcinogenesis, 1989, Volume: 10, Issue:9

    Topics: Animals; Bicarbonates; Butylhydroxybutylnitrosamine; Carcinogens; Hydrogen-Ion Concentration; Hyperplasia; Male; Nitrosamines; Papilloma; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium Bicarbonate; Urinary Bladder; Urinary Bladder Neoplasms

1989
Reduced DNA repair response of carcinogen-induced hyperplastic cells in rat urinary bladder exposed to N-methyl-N'-nitro-N-nitrosoguanidine in organ culture.
    Research communications in chemical pathology and pharmacology, 1989, Volume: 63, Issue:1

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; DNA Repair; Hyperplasia; Male; Methylnitronitrosoguanidine; Organ Culture Techniques; Rats; Rats, Inbred F344; Urinary Bladder

1989
Patterns of epithelial proliferation revealed by continuous administration of bromodeoxyuridine during urinary bladder carcinogenesis in rats.
    Japanese journal of cancer research : Gann, 1987, Volume: 78, Issue:9

    Topics: Animals; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Epithelial Cells; Epithelium; Hyperplasia; Male; Nitrosamines; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1987
[Effect of intrabladder instillation of various anticancer agents on carcinogenesis in rat bladder].
    Hinyokika kiyo. Acta urologica Japonica, 1988, Volume: 34, Issue:11

    Topics: Administration, Intravesical; Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Doxorubicin; Female; Hyperplasia; Mitomycin; Mitomycins; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1988
Summation effect of uracil on the two-stage and multistage models of urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Carcinogenesis, 1988, Volume: 9, Issue:11

    Topics: Animals; Body Weight; Butylated Hydroxyanisole; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Cocarcinogenesis; Hyperplasia; Male; Nitrosamines; Papilloma; Rats; Rats, Inbred F344; Uracil; Urinary Bladder; Urinary Bladder Neoplasms

1988
Nonspecific esterase reaction in hyperplastic urinary bladder epithelium induced by administration of N-butyl-N-(4-hydroxybutyl)nitrosamine, freezing and formalin instillation in rats.
    British journal of experimental pathology, 1988, Volume: 69, Issue:3

    Topics: Animals; Biomarkers, Tumor; Butylhydroxybutylnitrosamine; Carboxylesterase; Carboxylic Ester Hydrolases; Epithelium; Formaldehyde; Freezing; Hyperplasia; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms

1988
Promoting effect of sodium chloride in 2-stage urinary bladder carcinogenesis in rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Urological research, 1986, Volume: 14, Issue:4

    Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinoma; Cocarcinogenesis; Hyperplasia; Male; Nitrosamines; Papilloma; Rats; Rats, Inbred F344; Sodium Chloride; Urinary Bladder; Urinary Bladder Neoplasms

1986
Induction of high-grade, high-stage carcinomas in the rat urinary bladder.
    Cancer, 1987, Feb-01, Volume: 59, Issue:3

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelium; Flow Cytometry; Hyperplasia; Methylnitrosourea; Neoplasm Transplantation; Nitrosamines; Rats; Urinary Bladder; Urinary Bladder Neoplasms

1987
Scanning electron microscopy of changes in the urinary bladder in dogs treated with N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN).
    Urological research, 1987, Volume: 15, Issue:1

    Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Disease Models, Animal; Dogs; Epithelium; Female; Hyperplasia; Nitrosamines; Urinary Bladder; Urinary Bladder Neoplasms

1987
Trisodium nitriloacetate monohydrate: promoting effect in urinary bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
    Journal of the National Cancer Institute, 1985, Volume: 74, Issue:1

    Topics: Acetates; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Drug Synergism; Hyperplasia; Male; Nitrilotriacetic Acid; Nitrosamines; Organ Size; Papilloma; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms

1985
Pathological analysis of the carcinogenicity of sodium o-phenylphenate and o-phenylphenol.
    Oncology, 1985, Volume: 42, Issue:5

    Topics: Animals; Biphenyl Compounds; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Hyperplasia; Male; Microscopy, Electron, Scanning; Microvilli; Organ Size; Papilloma; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms

1985