butylhydroxybutylnitrosamine has been researched along with Bladder Cancer in 497 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 202 (40.64) | 18.7374 |
| 1990's | 146 (29.38) | 18.2507 |
| 2000's | 68 (13.68) | 29.6817 |
| 2010's | 69 (13.88) | 24.3611 |
| 2020's | 12 (2.41) | 2.80 |
| Authors | Studies |
|---|---|
| Abdulfattah, AY; Afify, H; Almousa, S; Bharadwaj, M; Casals, R; Ghoneum, A; Gonzalez, D; Kridel, S; Langsten, K; Said, N; Warren, B | 1 |
| Chenard, S; Conseil, G; Hamade, A; Hamilton, J; Koti, M; Li, D; Robert Siemens, D; Tyryshkin, K; Xu, M; Yolmo, P | 1 |
| Fujioka, M; Gi, M; Kakehashi, A; Kato, M; Matsue, T; Shiota, M; Suzuki, S; Tachibana, H; Uchida, J; Wanibuchi, H; Yamamoto, T | 1 |
| Akane, H; Cho, YM; Matsushita, K; Morikawa, T; Ogawa, K; Toyoda, T; Yamada, T | 1 |
| Fujioka, M; Gi, M; Kakehashi, A; Koda, S; Nakatani, T; Okuno, T; Suda, M; Suzuki, S; Wanibuchi, H; Yanagiba, Y; Yukimatsu, N | 1 |
| Degoricija, M; Haupt, B; Ivanisevic, T; Karaman, I; Korac-Prlic, J; Palada, V; Petkovic, M; Terzic, J; Vilovic, K | 1 |
| Grubbs, CJ; Juliana, MM; Lubet, RA; Miller, MS; Moeinpour, FL; Mohammed, A; Sei, S; Shoemaker, RH; Suen, CS | 1 |
| Akbarzadeh, A; Alavi, SE; Asadollahzadeh, MJ; Ebrahimi Shahmabadi, H; Ghaferi, M | 1 |
| Ando, R; Etani, T; Iida, K; Kato, H; Kawai, N; Nagai, T; Nagayasu, Y; Naiki, T; Naiki-Ito, A; Nozaki, S; Suzuki, S; Takahashi, S; Yasui, T | 1 |
| Matsushita, K; Morikawa, T; Ogawa, K; Toyoda, T; Yamada, T | 1 |
| Bonnal, JL; Mauroy, B; Philyppov, IB; Prevarskaya, N; Rock, A; Roudbaraki, M; Shuba, YM; Sotkis, GV | 1 |
| Ahmed, EK; Ezz, MK; Farrag, MA; Ibrahim, NK | 1 |
| Degoricija, M; Korac-Prlic, J; Terzić, J; Vilović, K; Vujević, S | 1 |
| Chiang, GG; Deo, R; Horn, JL; Hough, RP; Hsieh, AC; Jana, S; Lam, HM; Liu, Y; Sonenberg, N; Webster, KR; Wright, JL | 1 |
| Endou, H; Ikegami, M; Kanai, Y; Kansaku, N; Kume, E; Mutou, T; Takahashi, H; Wakui, S; Wempe, MF | 1 |
| Fujimoto, K; Hori, S; Miyake, M; Morizawa, Y; Nakai, Y; Onishi, S; Tanaka, N; Tatsumi, Y | 1 |
| Arantes-Rodrigues, R; Gil da Costa, RM; Oliveira, PA; Vasconcelos-Nóbrega, C | 1 |
| Chen, CH; Dai, YC; Haque, MM; Lin, LC; Lin, WH; Liu, YW; Wang, SC | 1 |
| Choudhary, D; Deng, X; Dyment, NA; Hainfeld, JF; Sanders, MM; Sasso, D; Smilowitz, HM; Tarmu, LJ; Taylor, JA; Xue, C | 1 |
| Beckford Vera, DR; Bixby, LM; Dunn, SS; Glatt, DM; Kim, WY; Parrott, MC; Saito, R; Serody, JS; Smith, CC; Vincent, BG | 1 |
| Eriksson, P; Foth, M; Ismail, NFB; Iwata, T; Knowles, MA; Kung, JSC; Salmond, JM; Sansom, OJ; Sjödahl, G; Tomlinson, D | 1 |
| He, C; Huang, L; Lei, P; Li, B; Liu, X; Shan, Y | 1 |
| Chauca-Diaz, A; Clouthier, D; Comi, GP; Dancik, GM; Frierson, HF; Lucchiari, S; Mallaredy, V; Moggio, M; Owens, C; Pagliarani, S; Ripolone, M; Ritterson Lew, C; Sottnik, JL; Theodorescu, D | 1 |
| Fujimoto, K; Gotoh, D; Hori, S; Iida, K; Itami, Y; Miyake, M; Morizawa, Y; Nakai, Y; Onishi, K; Onishi, S; Tanaka, N; Tatsumi, Y | 1 |
| Attalla, B; Bédard, A; Billger, M; Chang, J; Haile, S; Kirk, J; Söderberg, M | 1 |
| Chang, C; Hsu, I; Hsu, JW; Liang, L; Miyamoto, H; Shyr, CR; Wu, XR; Xu, D | 1 |
| Colaço, A; Costa, C; Lopes, C; Oliveira, PA; Santos, L; Vala, H; Vasconcelos-Nóbrega, C | 1 |
| Arantes-Rodrigues, R; Colaço, A; Ferreira, R; Gaivão, I; Neuparth, MJ; Oliveira, P; Palmeira, C; Pinto-Leite, R; Pires, MJ; Santos, L | 1 |
| Arantes-Rodrigues, R; Colaço, A; da Costa, RG; Lopes, C; Oliveira, P; Pinto-Leite, R | 1 |
| Du, Z; Guo, H; Li, C; Wang, R; Xiong, W; Xue, J; Yu, M | 1 |
| Chang, C; Chen, CC; Chuang, WM; Hsieh, TF; Hung, XF; Lin, MH; Ma, WL; Shyr, CR; Tsai, YR; Zhang, C; Zhang, Q | 1 |
| Chuang, KL; Da, J; Hsu, I; Lim, WX; O'Brien, JH; Pang, ST; Slavin, S; Yeh, S | 1 |
| DeGregorio, MW; Griffey, SM; Gutierrez, AM; Hanson, GK; Kao, CJ; Vang, DP; Wolf, M; Wurz, GT | 1 |
| Akaza, H; Fukiage, M; Harashima, H; Higuchi, M; Hosokawa, H; Ito, T; Miyazaki, J; Nakamura, T; Nakaya, A; Nakayama, T; Nishiyama, H; Yano, I | 1 |
| Scherr, DS | 1 |
| Amado, F; Antunes, D; Colaço, B; Domingues, MR; Duarte, JA; Ferreira, R; Maciel, E; Moreira-Gonçalves, D; Nunes, C; Oliveira, P; Padrão, AI; Pires, MJ; Santinha, D; Santos, LL; Vitorino, R | 1 |
| Beachy, PA; Honeycutt, JD; Hsieh, MH; Kawano, S; Lim, A; Odegaard, JI; Shin, K | 1 |
| Chang, CH; Fu, YC; Ho, HC; Li, JR; Shiu, YN; Shu, KH; Wu, MJ | 1 |
| Bilensoy, E; Erdogar, N; Eroglu, H; İskit, AB; Mungan, NA; Sargon, MF | 1 |
| Fukushima, S; Ikegami, M; Mutou, T; Takahashi, H; Wakui, S; Wanibuchi, H | 1 |
| Chan, HL; Chen, YY; Chuang, JJ; Dai, YC; Lin, WH; Lin, YL; Liu, YW | 1 |
| Allory, Y; Benhamou, S; Bernard-Pierrot, I; Biton, A; Caillault, A; Chapeaublanc, E; de Reyniès, A; Denoux, Y; Elarouci, N; Hérault, A; Kamoun, A; Krucker, C; Laplanche, A; Lebret, T; Lepage, ML; Letouzé, E; Maillé, P; Molinié, V; Neuzillet, Y; Ofualuka, K; Paoletti, X; Radvanyi, F; Rebouissou, S; Reyal, F; Sibony, M; Southgate, J; Soyeux, P; Vordos, D | 1 |
| Batourina, E; Cordon-Cardo, C; Dan, H; Dunlop, M; Mansukhani, M; Mendelsohn, C; Molotkov, A; Oyon, D; Schneider, K; Van Batavia, J; Wu, XR; Yamany, T | 1 |
| Dai, G; Deng, N; Fei, P; Feng, J; Gao, H; Guo, Y; Qiu, X; Zheng, P | 1 |
| Bode, A; Boring, DL; Grubbs, CJ; Juliana, MM; Lubet, RA; Minasian, L; Scheiman, JM; Steele, VE; White, J | 1 |
| Doi, K; Fang, H; Fujioka, M; Gi, M; Kakehashi, A; Tachibana, H; Wanibuchi, H; Xie, XL; Yamano, S | 1 |
| Balakrishnan, D; Prabhu, B; Sundaresan, S | 1 |
| Huang, X; Xu, Q; Xu, Y; Yang, J; Zhang, G; Zhang, Z | 1 |
| Bai, Y; Jiang, T; Kong, C; Li, L; Liu, D; Liu, T; Yang, Z | 1 |
| Gonzalgo, ML; He, Y; Hooker, E; Johnson, DT; Luong, R; Sun, Z; Yu, EJ | 1 |
| Dahm, HH; Rübben, H; von der Haar, C | 1 |
| Prabhu, B; Sivakumar, A; Sundaresan, S | 1 |
| Chang, C; Han, R; Hsu, I; Li, Y; Messing, EM; Niu, Y; Shang, Z; Tian, J; Wen, S; Yeh, S; Zhang, M | 1 |
| Dahm, HH; Lehnen-Holtum, V; Rübben, H | 1 |
| Ahlers, KE; Askeland, RW; Bondaruk, J; Chakravarti, B; Czerniak, BA; Fisher, RA; Ibeawuchi, SR; Lin, Z; Luo, Z; Maity, B; Platt, LT; Yang, J | 1 |
| Al-Tantawy, SM; El-Ashmawy, NE; El-Bahrawy, HA; Khedr, EG | 1 |
| Lee, JK; Theodorescu, D; Williams, PD | 1 |
| Desmond, R; Fischer, SM; Grubbs, CJ; Juliana, MM; Lubet, RA; Steele, VE | 1 |
| Cho, YH; Jung, KH; Kang, BS; Kim, CH; Kim, EJ; Kim, WJ; Lee, SJ; Moon, SK; Park, K | 1 |
| Hanai, T; Levin, R; Matsumoto, S; Shimizu, N; Uemura, H | 1 |
| Arantes-Rodrigues, R; Colaço, A; De la Cruz, PL; Lopes, C; Oliveira, PA; Palmeira, C; Santos, L | 1 |
| Chan, FL; Chan, PS; Chen, G; Zhang, X | 1 |
| Chihara, Y; Fujimoto, K; Hiasa, Y; Hirao, Y; Miyake, M | 1 |
| Afonso, J; Arantes-Rodrigues, R; Colaço, A; Da Silva, VM; De La Cruz, LF; Lopes, C; Lourenço, L; Oliveira, PA; Santos, L; Sousa-Diniz, C | 1 |
| Akaza, H; Fujii-Kuriyama, Y; Iida, K; Itoh, K; Mimura, J; Ohyama, C; Shimazui, T; Yamamoto, M | 1 |
| Boring, D; Grubbs, CJ; Juliana, MM; Kopelovich, L; Lubet, RA; Patlolla, J; Rao, CV; Steele, VE; Zhang, Y | 1 |
| Barbisan, LF; de Moura, NA; Grassi, TF; Rodrigues, MA | 1 |
| Evans, BJ; Fujii, N; Kotani, H; Mikami, Y; Nishiyama, H; Nishizawa, K; Ogawa, O; Oishi, S; Peiper, SC; Saito, R; Tanahara, N; Toda, Y; Watanabe, J | 1 |
| Hayashi, T; Kanetake, H; Miyata, Y; Nomata, K; Sagara, Y | 1 |
| Cunha, MF; Figueiredo, A; Garrido, P; Mota, A; Neto, P; Nunes, P; Parada, B; Pinto, R; Reis, F; Santos, P; Sereno, J; Teixeira, F; Teixeira-Lemos, E; Velada, I | 1 |
| Abbou, CC; Allory, Y; Amigorena, S; Battail, C; Benhamou, S; Bernard-Pierrot, I; Donnadieu, MH; Krumeich, S; Laé, M; Lebret, T; Lepage, ML; Maille, P; Radvanyi, F; Sastre-Garau, X; Stransky, N; Sugano, G; Théry, C | 1 |
| Ovčak, Z; Romih, R; Vidmar, G; Zupančič, D | 1 |
| Bode, AM; Grubbs, CJ; Juliana, MM; Lu, Y; Lubet, RA; Steele, VE; Townsend, R; Verney, ZM; You, M | 1 |
| Chyau, CC; Hsu, JD; Lee, HJ; Ou, TT; Wang, CJ; Wu, CH | 1 |
| Cunha, FX; Figueiredo, A; Garrido, P; Mota, A; Neto, P; Nunes, S; Parada, B; Pinto, R; Reis, F; Rocha-Pereira, P; Rodrigues-Santos, P; Ruivo, J; Sereno, J; Teixeira, F; Teixeira-Lemos, E | 1 |
| Colaço, A; Lopes, C; Oliveira, PA; Palomino, LF; Santos, L; Vala, H; Vasconcelos-Nóbrega, C | 1 |
| Akaza, H; Harashima, H; Joraku, A; Kawai, K; Kohama, H; Miyazaki, J; Nakamura, T; Nakaya, A; Nishiyama, H; Yano, I | 1 |
| Fujii, N; Kobayashi, T; Kotani, H; Masutani, H; Matsui, Y; Nishiyama, H; Nishizawa, K; Ogawa, O; Oishi, S; Saito, R; Toda, Y; Yodoi, J | 1 |
| Bae, SC; Kim, J; Kim, SK; Kim, WJ; Lee, OJ; Yun, SJ | 1 |
| Guttenplan, JB; He, Z; Kosinska, W; Wu, XR; Zhao, ZL | 1 |
| Arantes-Rodrigues, R; Brochado, P; Cardoso, ML; Colaço, A; Ferreira, R; Guedes-Teixeira, CI; Lopes, C; Oliveira, PA; Palmeira, C; Palomino, LF; Pinto-Leite, R; Salvador, A; Santos, L; Vasconcelos-Nóbrega, C | 1 |
| Chen, SS; Huang, CC; Lin, PY; Lin, YL; Liu, YW | 1 |
| Albuquerque, IL; Almeida, PR; Alves, LA; Castro, JD; Dornelas, CA; Fechine-Jamacaru, FV; Lemos, TL; Magalhães, HI; Moraes, ME; Moraes, MO; Souza, AJ | 1 |
| Chan, KS; Ho, PL; Jian, W; Lay, EJ; Parra, D | 1 |
| Izumi, K; Li, Y; Miyamoto, H | 1 |
| Albuquerque, IL; Alves, MK; Castro, JD; de Almeida, PR; Dias, TA; Dornelas, CA; Faria, MH; Fechine-Jamacaru, FV; Lemos, TL; Magalhães, HI; Moraes, ME; Moraes, MO; Rabenhorst, SH | 1 |
| Kakehashi, A; Kato, M; Wanibuchi, H; Wei, M; Xie, XL; Yamano, S; Yunoki, T | 1 |
| Figueiredo, A; Mota, A; Neto, P; Parada, B; Pinto, Â; Reis, F; Rocha-Pereira, P; Sereno, J; Teixeira, F; Xavier-Cunha, M | 1 |
| Johnson, DT; Lee, JT; Lee, SH; Lin, D; Luong, R; Peng, Y; Shaltouki, A; Sun, Z; Wang, Y | 1 |
| Cunha, MF; Fernandes, JC; Garrido, P; Parada, B; Pintado, ME; Reis, F; Santos-Silva, A; Sereno, J | 1 |
| Eisenhardt, A; Lümmen, G; Otto, T; Rübben, H; Sperling, H; vom Dorp, F | 1 |
| Furukawa, F; Hirose, M; Imazawa, T; Masegi, T; Nakamura, H; Nishikawa, A; Okazaki, K; Son, HY; Yamagishi, M | 1 |
| Al'-Shurki, SKh; Mel'nikov, AS; Pliss, GB; Pliss, MG | 1 |
| Iseda, T; Takei, S; Yokoyama, M | 1 |
| Matsushima, M; Sato, D | 1 |
| Chung, FL; Morse, MA; Nishikawa, A | 1 |
| Hirose, M; Imazawa, T; Masegi, T; Nishikawa, A; Okazaki, K; Umemura, T | 1 |
| Doi, K; Fukushima, S; Mitsuhashi, M; Morimura, K; Nakatani, T; Wada, S; Wanibuchi, H; Wei, M | 1 |
| Fradet, Y; Girard, J; Hamed, S; Hovington, H; Jeannotte, L; LaRue, H; Latulippe, E | 1 |
| Akaza, H; Hattori, K; Iida, K; Itoh, K; Kawai, K; Kumagai, Y; Oyasu, R; Shimazui, T; Yamamoto, M | 1 |
| Abdul-Ghani, R; Ariel, I; Ayesh, B; Ayesh, S; Birman, T; de Groot, N; Gofrit, O; Hochberg, A; Pizov, G; Schneider, T; Sidi, AA; Smith, Y | 1 |
| Baffa, R; Cesari, R; Croce, CM; Fong, LY; Giarnieri, E; Gomella, LG; Ishii, H; Sevignani, C; Vecchione, A; Zanesi, N | 1 |
| Altieri, DC; Fong, LY; Grubbs, CJ; Huebner, K; Juliana, MM; Kavanaugh, C; Kopelovich, L; Lubet, RA; Soong, SJ; Steele, VE | 1 |
| Brams, A; Dunois-Lardé, C; Levrel, O; Radvanyi, F; Thiery, JP | 1 |
| Altieri, DC; Eisenberg, D; Garlick, DS; Plescia, J; Salz, W; Sun, TT; Weiss, RM; Wu, XR | 1 |
| Carrascosa, MJ; Collado, M; Diaz-Meco, MT; Duran, A; Flores, JM; García-Cao, I; Martín-Caballero, J; Moscat, J; Serrano, M | 1 |
| Hara, A; Kohno, H; Mori, H; Quang, le B; Rahman, KM; Sugie, S; Suzuki, R; Tanaka, T; Ushida, J; Vinh, PQ | 1 |
| Fukushima, S; Hagiwara, A; Koide, A; Makino, S; Mori, S; Mori, Y; Murai, T; Tatematsu, K; Wanibuchi, H | 1 |
| Asano, N; Hata, K; Hirose, Y; Iwasaki, T; Kobayashi, H; Kuno, T; Mori, H; Oyama, T; Qiang, SH; Yamada, Y; Zhi, H | 1 |
| Akaza, H; Hattori, K; Iida, K; Joraku, A; Oyasu, R; Tsukamoto, S | 1 |
| Lopes, CA; Lourenço, LM; Oliveira, PA; Palmeira, C | 1 |
| Hwang, CH; Kim, HJ; Park, JY; Sohng, I | 1 |
| Ayesh, S; Birman, T; Dinaburg, A; Gofrit, ON; Hochberg, A; Ohana, P | 1 |
| Fukushima, S; Morimura, K; Wanibuchi, H; Wei, M | 1 |
| Barbisan, LF; Bidinotto, LT; Rocha, NS; Salvadori, DM; Spinardi-Barbisan, AL | 1 |
| Barbisan, LF; de Camargo, JL; de Oliveira, ML; Ihlaseh, SM; Teràn, E | 1 |
| Colaço, A; De la Cruz, LF; Lopes, C; Lopes, P; Oliveira, PA | 1 |
| Hata, K; Ikeda, R; Kohno, H; Miyamoto, S; Miyazawa, K; Suzuki, K; Suzuki, R; Tanaka, T; Yano, M; Yasui, Y | 1 |
| Adega, F; Chaves, RM; Colaço, AA; De la Cruz P, LF; Guedes-Pinto, H; Lopes, CA; Oliveira, PA; Palmeira, CA | 1 |
| Grubbs, CJ; Lubet, RA; Yao, R; Yi, Y; You, M | 1 |
| Akaza, H; Iida, K; Itoh, K; Kumagai, Y; Maher, JM; Mori, Y; Oyasu, R; Shimazui, T; Yamamoto, M | 1 |
| Bucala, R; Claffey, K; Hegde, P; Kuchel, GA; Leng, L; Pilbeam, C; Taylor, JA; Tsimikas, J; Voznesensky, OS | 1 |
| Fujimoto, K; Hirao, Y; Matsumura, Y; Okajima, E; Ozono, S; Tani, Y | 1 |
| Colaco, AA; De la Cruz P, LF; Lopes, CA; Oliveira, PA; Palmeira, CA | 1 |
| Asamoto, M; Hikosaka, A; Kohri, K; Nakanishi, M; Ogawa, K; Sato, SY; Shirai, T; Sugiura, S; Takeshita, F | 1 |
| Agarwal, C; Agarwal, R; Glode, LM; Gu, M; Harrison, G; Raina, K; Singh, RP; Tyagi, A | 1 |
| Baffa, R; Croce, CM; Fassan, M; Giarnieri, E; Gomella, LG; Iozzo, RV; Ishii, H; Sevignani, C; Vecchione, A | 1 |
| Davis, W; Fahey, JW; Lister, C; Mhawech-Fauceglia, P; Munday, CM; Munday, JS; Munday, R; Paonessa, JD; Tang, L; Wilson, P; Zhang, Y | 1 |
| Barnes, S; Grubbs, CJ; Jones, K; Juliana, MM; Leahy, M; Moore, R; Prasain, JK; Roderick, R | 1 |
| Endho, N; Hashimoto, Y; Hojo, H; Masuko, T | 1 |
| Hicks, RM | 2 |
| Grover, A; Jensen, R; King, E; Kromhout, L; Vanderlaan, M; Young, IT | 1 |
| Gelsema, ES; Hunink, M; Queiros, CE; Timmers, T | 1 |
| Fukushima, S; Ito, N; Koiso, K; Niijima, T; Ohtani, M | 1 |
| Fujita, J; Ito, Y; Tokuda, H; Yoshida, O | 1 |
| Habs, M; Schmähl, D; Tacchi, AM | 1 |
| Fukushima, S; Ito, N; Koiso, K; Niijima, T; Ohtani, M; Okamura, T; Sakata, T | 1 |
| Babaya, K | 1 |
| Hoffman, JW; Jensen, RH; King, EB; Kromhout, LK; Vanderlaan, M | 1 |
| Fukushima, S; Hagiwara, A; Ito, N; Kitaori, M; Shibata, M | 1 |
| Yagishita, T | 1 |
| Fukushima, S; Hasegawa, R; Ito, N; Sakata, T; Shirai, T | 1 |
| Fukushima, S; Hagiwara, A; Imaida, K; Ito, N; Shirai, T | 1 |
| Kunze, E; Töpfer, S; Zöller, N | 1 |
| Festing, MF; Gwynne, J; Hart, MG; Hawkey, CM; Hicks, RM; Turton, JA | 1 |
| Daniel, DS; Irving, CC; Murphy, WM | 1 |
| Lee, RE; Moon, RC; O'Brien, A; Ornellas, EP; Thomas, W; Westerman, MP | 1 |
| Wada, S | 1 |
| Kakizoe, T; Sugimura, T; Tanaka, K; Tanooka, H | 1 |
| Kunze, E; Niemann, U; Wöltjen, HH | 2 |
| Fukushima, S; Hirose, M; Inui, M; Ito, N; Sakata, T | 1 |
| Fukushima, S; Ikawa, E; Ito, N; Kurata, Y; Shibata, M | 2 |
| Aota, Y; Kobayashi, O; Koshikawa, T; Mitsuta, H; Murase, T | 1 |
| Honma, Y; Kakizoe, T; Komatsu, H; Niijima, T; Nishio, Y | 1 |
| Fujita, H; Fujita, J; Mikuni, I; Yoshida, O | 1 |
| Honma, Y; Kakizoe, T; Niijima, T; Nishio, Y; Sugimura, T | 1 |
| Fukushima, S; Hagiwara, A; Ito, N; Ogiso, T; Shibata, M | 1 |
| Arai, M; Conran, PB; Fukushima, S; Ito, N; Lurie, AG; Rippey, RM; Tatematsu, M | 1 |
| Fukushima, S; Imaida, K; Ito, N; Miyata, Y | 1 |
| Babaya, K; Hirao, Y; Iwai, A; Matsuki, H; Nakatsuji, F; Okajima, E; Samma, S; Tabata, S; Uemura, H | 1 |
| Fukushima, S; Hirose, M; Ito, N; Shirai, T | 2 |
| Miyakawa, M; Yoshida, O | 1 |
| Babaya, K; Hiramatsu, T; Hirao, Y; Ijuin, M; Kihoin, K; Maruyama, Y; Ohara, S; Okajima, E; Tanaka, M | 1 |
| Fukushima, S; Hasegawa, R; Imaida, K; Ito, N; Nakanishi, K; Shirai, T | 1 |
| Anjo, T; Aoki, J; Okada, M; Suzuki, E | 1 |
| Honma, Y; Kakizoe, T; Komatsu, H; Nagase, S; Niijima, T; Sugimura, T | 1 |
| Fukushima, S; Ito, N; Nakanishi, K; Shirai, T | 1 |
| Mochizuki, M; Okada, M; Suzuki, E | 2 |
| Hagiwara, A; Imaida, K; Ito, N; Nakanishi, K; Shibata, M; Tatematsu, M | 1 |
| Hashimoto, Y; Masuko, T | 2 |
| Fukushima, S; Hagiwara, A; Ito, N; Nakanishi, K; Tamano, S | 1 |
| Babaya, K; Chmiel, JS; Miyata, Y; Oyasu, R | 1 |
| Honma, Y; Kakizoe, T; Kawachi, T; Komatsu, H; Nagase, S; Niijima, T; Sugimura, T | 1 |
| Fukushima, S; Hasegawa, R; Hirose, M; Ito, N; Murasaki, G; Nakanishi, K | 1 |
| Dahm, HH; Friedrichs, R; Lutzeyer, W; Rübben, H; Rüttgers, L; von Uelft, W | 1 |
| Fukushima, S; Hatano, A; Hirose, M; Ito, N; Nakanowatari, J; Okuda, M | 1 |
| Arai, M; Fukushima, S; Ito, N; Shirai, T; Tsuda, H | 1 |
| Becci, PJ; Frickel, F; McCormick, DL; Moon, RC; Paust, J; Shealy, YF; Sporn, MB | 1 |
| Fujii, M; Kato, K; Mori, H; Takahashi, M | 1 |
| Arai, Y; Fukushima, S; Ito, N; Nishizuka, Y; Ogiso, T | 1 |
| Honma, Y; Kakizoe, T; Komatsu, H; Niijima, T; Sugimura, T | 1 |
| Babaya, K; Hiramatsu, T; Hirao, Y; Horii, Y; Ijuin, M; Kaneko, Y; Kihoin, K; Kubota, K; Moriya, A; Ohara, S; Okajima, E; Okamoto, M; Okamura, K; Samma, S | 1 |
| Babaya, K; Hijioka, T; Hiramatsu, T; Hirao, K; Hirao, Y; Ijuin, M; Ikuma, S; Ohara, S; Ohishi, H; Okajima, E; Shiomi, T | 1 |
| Irving, CC; Murphy, WM | 1 |
| Fukushima, S; Hirose, M; Imaida, K; Ito, N; Murasaki, G | 1 |
| Becci, PJ; McCormick, DL; Moon, RC; Ronan, SS | 1 |
| Okada, M; Suzuki, E | 1 |
| Iiyoshi, M; Okada, M; Suzuki, E | 2 |
| Fukushima, S; Hagiwara, A; Hasegawa, R; Hirose, M; Ito, N | 1 |
| Kakizoe, T; Kawachi, T; Komatsu, H; Niijima, T; Sugimura, T | 1 |
| Hashimoto, Y; Mochizuki, M; Okada, M; Suzuki, E; Takeda, Y | 1 |
| Aoki, J; Okada, M; Suzuki, E | 1 |
| Numoto, S; Otsuka, H; Yoshida, M | 1 |
| Aoyagi, M; Kakizoe, T; Kawachi, T; Matsukura, N; Sugimura, T | 1 |
| Anichkov, NM; Lomakina, II; Zubzhitskiĭ, IuN | 1 |
| Arai, M; Babaya, K; Fukushima, S; Ito, N; Miyata, Y; Murasaki, G | 1 |
| Arai, M; Hasegawa, R; Hirose, M; Ito, N; Nakanishi, K; Ogiso, T | 1 |
| Shirai, T | 1 |
| Hirao, Y; Izumi, K; Oyasu, R | 1 |
| Hicks, RM; James, C; Webbe, G | 1 |
| Becci, PJ; Brown, CC; Moon, RC; Sporn, MB; Strum, JM; Thompson, HJ | 1 |
| Becci, PJ; Brown, CC; Grubbs, CJ; Moon, RC; Shealy, YF; Sporn, MB; Stanek, EJ; Thompson, HJ | 1 |
| Nakagawa, S; Sugimoto, K; Watanabe, H; Wu, B | 1 |
| Hara, A; Hirose, Y; Kawamori, T; Makita, H; Mori, H; Ohnishi, M; Satoh, K; Tanaka, T | 1 |
| Fukushima, S; Makino, S; Masui, T; Mori, S; Murai, T; Oohara, T; Tatematsu, M; Yamamoto, S | 1 |
| Chen, T; Fukushima, S; Kitano, M; Mori, S; Murai, T | 1 |
| Matsuoka, N; Sugimoto, M; Takenaka, I; Zhang, X | 1 |
| Hirose, M; Imaida, K; Shibata, M; Shirai, T; Tagawa, Y; Takahashi, S | 1 |
| Baumgartner, R; Hofstetter, A; Jocham, D; Kriegmair, M; Lumper, W; Riesenberg, R; Sassy, T; Stocker, S; Unsöld, E | 1 |
| Hashimoto, Y; Hojo, H; Kaneko, A; Kayagaki, N; Saki, M | 1 |
| Takenaka, I; Zhang, XH | 3 |
| Fukushima, S; Hagiwara, A; Imaida, K; Takahashi, S; Tamano, S; Tanaka, H | 1 |
| Asamoto, M; Fukushima, S; Imaida, K; Shirai, T; Takahashi, S | 1 |
| Airoldi, L; Bonfanti, M; Chiappetta, L; De Gregorio, G; Fanelli, R; Lolli, M; Magagnotti, C; Medana, C | 1 |
| Don, I; Fukushima, S; Masui, T; Ogawa, K; Shirai, T; Takada, N | 1 |
| Fukushima, S; Hosono, M; Makino, S; Mori, S; Murai, T; Oohara, T; Takeda, R; Takeuchi, Y | 1 |
| Ito, N; Montesano, R; Ogawa, K; Shibata, MA; Shirai, T; Takahashi, S; Tsuda, H; Wild, CP | 1 |
| Fukushima, S; Hakoi, K; Hirose, M; Ogawa, K; Takaba, K | 1 |
| Kudoh, T; Oh, SC; Suzuki, T; Yanagisawa, T | 1 |
| Asakawa, E; Boomyaphiphat, P; Fukushima, S; Masui, T; Tamano, S | 1 |
| Fukushima, S; Hayashi, Y; Hosono, M; Makino, S; Mori, S; Murai, T; Ohhara, T; Takeda, R; Takeuchi, Y | 1 |
| Akaza, H; Aso, Y; Homma, Y; Matsushima, H; Nomoto, K; Tomita, K; Yokokura, T | 1 |
| Fukushima, S; Iwata, H; Matsui-Yuasa, I; Murai, T; Otani, S; Otoshi, T; Yamaguchi, S; Yamamoto, S | 1 |
| Kojima, T; Mori, H; Morishita, Y; Okumura, A; Suzui, M; Tanaka, T | 1 |
| Fan, X | 1 |
| Detrisac, CJ; Kelloff, GJ; Moon, RC; Sigman, CC; Steele, VE; Thomas, CF | 1 |
| de Viragh, PA; Detrisac, CJ; Hohl, D; Huber, M; Roop, DR; Ruf Olano, B; Schnyder, UW | 1 |
| Matsuoka, N | 1 |
| Klän, R; Knispel, HH; Meier, T | 1 |
| Akaza, H; Imada, S; Koiso, K; Otani, M | 1 |
| Fukushima, S; Ichinose, M; Inoue, H; Masui, T; Miki, K; Tatematsu, M; Yamamoto, S; Yonezawa, S | 1 |
| Dong, Y; Fukushima, S; Inada, K; Masui, T; Nakanishi, H; Takada, N; Tatematsu, M; Yamamoto, S | 1 |
| Detrisac, CJ; Hawk, ET; Kelloff, GJ; McCormick, DL; Rao, KV; Steele, VE | 1 |
| Takenaka, I; Zhang, X | 2 |
| Asai, Y; Fukushima, S; Hato, F; Ikemoto, S; Iwata, H; Kamizuru, M; Kinoshita, Y; Kishimoto, T; Wada, S | 1 |
| de Camargo, JL; de Oliveira, ML; Fukushima, S; Souza Rocha, N | 1 |
| Jin, L; Takenaka, I; Zhang, XH | 1 |
| Inui, M; Matsumoto, K; Miyanaka, H; Nakamura, T; Nishi, N; Takenaka, I; Wada, F; Yasumoto, A | 1 |
| Chen, H; Endo, G; Fukushima, S; Hori, T; Wanibuchi, H; Yamamoto, S; Yoshida, K | 1 |
| Kanamaru, H; Li, B; Matsukawa, S; Okada, K; Saikawa, S | 1 |
| Akaza, H; Ami, Y; Ideyama, Y; Imada, S; Koiso, K; Takenaka, T | 1 |
| Akuzawa, Y; Endo, F; Kurashige, S | 2 |
| Fukushima, S; Hosono, M; Machino, S; Makino, S; Matsuda, T; Mori, S; Murai, T; Oohara, T; Takashima, A; Wanibuchi, H; Yamashita, H | 1 |
| Kawabe, M; Orita, SI; Ozaki, M; Shibata, MA; Shirai, T; Takahashi, S | 1 |
| Akaza, H | 1 |
| Hoshi, S; Kawamura, S; Ohyama, C; Orikasa, S; Saito, S; Satoh, M; Yoshikawa, K | 1 |
| Hino, A; Itakura, M; Iwahana, H; Izumi, K; Kudo, E; Min, H; Yoshimoto, K | 1 |
| Akai, H; Denda, A; Endo, T; Fukuda, T; Hirao, Y; Konishi, Y; Majima, T; Nir, Z; Nishino, H; Okajima, E; Ozono, S; Tsutsumi, M | 1 |
| Deguchi, T; Hara, A; Kawada, Y; Minoshima, K; Sakai, S; Sato, K; Takeuchi, T; Taniguchi, M | 2 |
| Hiai, H; Kamoto, T; Makino, S; Mori, S; Murai, T; Yamada, Y; Yoshida, O | 1 |
| Chou, C; Fukushima, S; Hosono, M; Machino, S; Makino, S; Mori, S; Murai, T | 1 |
| Fukushima, S; Kishimoto, T; Lee, CC; Sugimura, K; Wada, S; Wanibuchi, H; Yamamoto, S | 1 |
| Chen, T; Fukushima, S; Makino, S; Mori, S; Morimura, K; Murai, T; Oohara, T; Tatematsu, M; Wanibuchi, H; Yamamoto, S | 1 |
| Hirao, Y; Iwai, A; Momose, H; Okajima, E; Ozono, S; Samma, S; Tabata, S; Tsumatani, K; Tsunemi, K; Uemura, H; Yoshida, K | 1 |
| Deguchi, T; Hirose, Y; Kawada, Y; Mori, H; Tanaka, T; Yang, M | 1 |
| Chen, T; Fukushima, S; Gen, H; Makino, S; Mori, S; Murai, T; Oohara, T; Wanibuchi, H; Yamamoto, S | 1 |
| Arnold, L; Cohen, SM; de Oliveira, ML; Ogawa, K; St John, MK; Uzvolgyi, E | 1 |
| Akai, H; Denda, A; Konishi, Y; Nishino, H; Okajima, E; Oshima, S; Ozono, S; Sakamoto, H; Tsutsumi, M | 1 |
| Doteuchi, M; Fukushima, S; Hosono, M; Makino, S; Mori, S; Murai, T; Oohara, T; Yamashita, H | 1 |
| Fukami, H; Fukushima, S; Tatematsu, M; Yamamoto, M; Yamamoto, S | 1 |
| Akai, H; Denda, A; Kitayama, W; Konishi, Y; Okajima, E; Ozono, S; Sasaki, Y; Takahama, M; Wakabayashi, K | 1 |
| Futakuchi, M; Hirose, M; Kimoto, N; Ogawa, K; Sano, M; Shirai, T; Yamaguchi, T | 1 |
| Chen, T; Fukushima, S; Ishikawa, T; Kitano, M; Matsukuma, S; Murai, T; Nakatsuru, Y; Wanibuchi, H; Yamamoto, S | 1 |
| Fukushima, S; Kawasaki, H; Koide, A; Mori, Y; Ozaki, K; Seki, T; Sukata, T; Uwagawa, S; Wanibuchi, H; Yamamoto, S; Yoshitake, A | 1 |
| Itoh, K; Kawai, K; Kubota, Y; Nakada, T; Sasagawa, I; Yanai, H | 1 |
| Chen, MT; Huang, CH; Huang, CN; Kuo, KW; Tsai, JL; Wu, WJ | 1 |
| Frolov, AG; Iogannsen, MG; Pliss, GB; Vlasov, NN | 1 |
| Arakawa, Y; Fukushima, S; Hiai, H; Higashi, S; Kamoto, T; Makino, S; Mori, S; Murai, T; Yoshida, O; Yoshitomi, M | 1 |
| Ariel, I; Ayesh, S; de Groot, N; Elkin, M; Hochberg, A; Schneider, T | 1 |
| Brasic, GM; Gould, MN; Grubbs, CJ; Haag, JD; Kelloff, GJ; Lubet, RA; Newton, MA; Shepel, LA | 1 |
| Chen, TX; Fukushima, S; Kitano, M; Murai, T; Wanibuchi, H; Yamamoto, S | 1 |
| Fukushima, S; Lee, CC; Min, W; Salim, EI; Sukata, T; Wanibuchi, H; Yamamoto, S | 1 |
| Furusato, M; Masaoka, T; Muto, T; Sasaki, S; Takahashi, H; Ushigome, S; Wakui, S | 1 |
| Chen, TX; Fukushima, S; Mori, S; Morimura, K; Murai, T; Wanibuchi, H; Yamamoto, S | 1 |
| Sato, D | 1 |
| Akimoto, M; Kimura, G; Osawa, S; Terashima, Y | 1 |
| Endo, G; Fukushima, S; Li, W; Salim, EI; Wanibuchi, H; Yamamoto, S; Yoshida, K | 1 |
| Fukushima, S; Hayashi, S; Mori, S; Salim, EI; Wanibuchi, H; Youssef, EM | 1 |
| Akita, H; Ito, Y; Kohri, K; Okamura, T; Tozawa, K; Yamada, Y | 1 |
| Cardoso, PR; Fukushima, S; Padovani, CR; Viana de Camargo, JL; Vieira de Oliveira, S | 1 |
| Akimoto, M; Endo, W; Himeno, S; Imura, N; Kondo, Y; Lazo, JS; Mita, M; Nemoto, K; Suzuki, Y | 1 |
| Fukushima, S; Ichihara, T; Kishimoto, T; Lee, CC; Sugimura, K; Wada, S; Wanibuchi, H; Yamamoto, S | 1 |
| Aoyama, T; Ba, Y; Furuuchi, K; Hamada, J; Harada, H; Hirai, A; Hirai, K; Katsuoka, Y; Moriuchi, T; Nakata, D; Nishida, T; Shibahara, N; Tada, M; Tonoki, H; Yamamoto, K | 1 |
| Ebisuno, S; Inagaki, T; Kohjimoto, Y; Nishihata, M; Nishikawa, T; Ohkawa, T; Watanabe, T | 1 |
| Chen, T; Fukushima, S; Lee, CC; Na, Y; Wanibuchi, H; Yamamoto, S | 1 |
| Fujita, K; Nagae, H; Otawara, Y; Suzuki, K | 1 |
| Denda, A; Kitayama, W; Konishi, Y; Okajima, E; Tsujiuchi, T | 1 |
| Asamoto, M; Kimoto, N; Nakanishi, M; Ogawa, K; Shirai, T; Takahashi, S | 1 |
| Chen, TX; Fukushima, S; Hayashi, S; Morimura, K; Wanibuchi, H; Wei, M; Yamamoto, S | 1 |
| Fukushima, S; Kim, S; Morimura, K; Salim, EI; Wanibuchi, H; Yamamoto, S; Yano, Y | 1 |
| Adamek, M; Gabius, HJ; Kunze, E; Schulz, H | 1 |
| Bando, Y; Chone, Y; Izumi, K; Jiao, Z; Kinouchi, T; Kitaura, K; Minami, T; Mochizuki, M; Ohnishi, Y; Suzuki, Y; Uehara, H; Yamada, T | 1 |
| Fukushima, S; Saeki, K; Suzuki, K; Takaba, K; Wanibuchi, H | 1 |
| Akaza, H; Asamoto, M; Matsuoka, Y; Ochiya, T; Ota, T; Sekiya, T; Terada, M; Toriyama-Baba, H; Tsuda, H; Yamamoto, F | 1 |
| Fukushima, S; Kishimoto, T; Masuda, C; Otani, S; Sekine, K; Tsuda, H; Wanibuchi, H; Yano, Y | 1 |
| Grubbs, CJ; Hill, DL; Kelloff, GJ; Koki, AT; Leahy, KM; Lubet, RA; Masferrer, JL; Seibert, K; Steele, VE | 1 |
| Akasaka, S; Akimoto, M; Shimada, T; Shimizu, H; Suzuki, S | 1 |
| Futakuchi, M; Hirose, M; Iwata, T; Kasai, M; Kimoto, N; Shirai, T | 1 |
| Akasaka, S; Akimoto, M; Igarashi, T; Shimada, T; Shimizu, H; Suzuki, S | 1 |
| Fukushima, S | 3 |
| Dahiya, R; Deguchi, M; Igawa, M; Ribeiro-Filho, L; Shigeno, K; Shiina, H; Terashima, M; Urakami, S; Yoneda, T | 1 |
| Khavinson, VK; Malinin, VV; Mel'nikov, AS; Pliss, GB | 1 |
| Fukushima, S; Gen, H; Hosono, M; Makino, S; Min, W; Mitsuhashi, M; Mori, S; Morimura, K; Murai, T; Oohara, T; Wanibuchi, H; Yamamoto, S | 1 |
| Hagiwara, A; Ito, N; Kadota, T; Kawabe, M; Maemura, S; Sano, M; Shirai, T; Tamano, S; Tanaka, H; Yanagisawa, T | 1 |
| Khavinson, VKh; Malinin, VV; Mel'nikov, AS; Pliss, GB | 1 |
| Deguchi, T; Hara, A; Katayama, M; Mori, H; Sugie, S; Tanaka, T; Vinh, PQ; Yamada, Y | 1 |
| Pan, C; Song, G; Wu, B | 1 |
| Itoh, Y; Kohri, K; Okamura, T; Tozawa, K; Yamada, Y | 1 |
| Arai, H; Hananouchi, M; Hirose, M; Ito, N; Murasaki, G; Shirai, T | 1 |
| Azuma, C; Kono, N; Muraoka, N; Sasaki, N; Tanahashi, T | 1 |
| Kunze, E; Schatt, S; Schauer, A | 1 |
| Knuze, E; Schauer, A | 1 |
| Nishi, M | 1 |
| Hashimoto, Y; Okada, M; Suzuki, E | 1 |
| Becci, PJ; Grubbs, CJ; Moon, RC; Thompson, HJ | 1 |
| Nagao, M; Seino, Y; Suzuki, E; Yahagi, T; Yasuo, K | 1 |
| Hashimoto, Y; Kitagawa, HS | 1 |
| Anichkov, NM | 1 |
| Irving, CC; Murphy, WM; Tice, AJ | 1 |
| Becci, PJ; Brown, CC; Grubbs, CJ; Moon, RC; Thompson, HJ | 1 |
| Conran, PB; Ito, N; Lurie, AG; Rippey, RM; Tatematsu, M | 1 |
| Eliseev, VV; Vlasov, NN | 1 |
| Kawakita, J | 1 |
| Hagiwara, A; Hasegawa, R; Ito, N; Miyata, Y; Shirai, T; Tsuda, H | 1 |
| Cohen, SM; Fukushima, S; Ito, N; Shinohara, Y; Shirai, T; Tatematsu, M | 1 |
| Fukushima, S; Ito, N; Nakanishi, K; Ogiso, T; Shibata, M; Shirai, T | 1 |
| Becci, PJ; Brown, CC; Grubbs, CJ; Moon, RC; Sporn, MB; Squire, RA; Thompson, HJ | 1 |
| Kakizoe, T; Kawachi, T; Okada, M | 1 |
| Cohen, SM; Fukushima, S; Ito, N; Murasaki, G; Tsuda, H | 1 |
| Fukushima, S; Ito, N; Matayoshi-Miyasato, K; Miyata, Y; Murasaki, G; Ogiso, T; Tsuda, H | 1 |
| Azuma, C; Suzawa, N; Tanahashi, NK | 1 |
| Cohen, SM; Fukushima, S; Ito, N; Shinohara, Y; Tatematsu, M | 1 |
| Hananouchi, M; Hirose, M; Miyata, Y; Mizutani, M; Tatematsu, M | 1 |
| Fukushima, S; Murasaki, G; Shirai, T; Tatematsu, M; Tsuda, H | 1 |
| Fukushima, S; Kinoshita, H; Miyata, Y; Murasaki, G; Tsuda, H | 1 |
| Esumi, H; Kakizoe, T; Kawachi, T; Sugimura, T; Takeuchi, T; Umezawa, H | 1 |
| Brown, CC; Farrow, GM; Goodman, DG; Grubbs, CJ; Moon, RC; Sporn, MB; Squire, RA; Stinson, SF | 1 |
| Fukushima, S; Hananouchi, M; Hirose, M; Ogiso, T; Shirai, T | 1 |
| Hiramatsu, T; Ijuin, M; Iriya, K; Matsushima, S; Okajima, E | 1 |
| Kakizoe, T; Kawachi, T; Sugimura, T; Takayasu, H; Takeuchi, T | 1 |
| Ito, N | 1 |
| Frolov, AG; Pliss, GB | 3 |
| Fukushima, S; Matsui-Yuasa, I; Otani, S; Shibata, MA; Takada, N; Yano, Y | 1 |
| Institoris, L; Jeney, A; Szende, B | 1 |
| Fukushima, S; Kawabe, M; Shibata, M; Shirai, T; Tamano, S | 1 |
| Fukuzawa, S; Hashimura, T; Kanamaru, H; Nishio, Y; Yoshida, O; Yu, A | 1 |
| Fukushima, S; Kurata, Y; Ono, S; Sano, M; Shichino, Y | 1 |
| Akaza, H; Kakizoe, T; Koiso, K; Miyanaga, N; Noguchi, R; Ohtani, M; Sasaki, A; Tanaka, Y; Tobisu, K | 1 |
| Akaza, H; Aso, Y; Matsuki, K | 1 |
| Cohen, SM; Garland, EM; Macatee, TL; Mann, AM; Masui, T; Okamura, T; Smith, RA | 2 |
| Fukushima, S; Kawabe, M; Mori, Y; Ni-I, H; Okada, M; Shirai, T; Tamano, S | 1 |
| Debiec-Rychter, M; Miller, FR; Rak, JW; Wang, CY | 1 |
| Kudo, K; Suwa, J | 1 |
| Asakawa, M; Fukui, J; Kishimoto, T; Maekawa, M; Wada, S; Yasumoto, R | 1 |
| Kogawa, T; Kudoh, S; Kudoh, T; Mollik, AU; Suzuki, T; Tanaka, S | 1 |
| Otto, T; Recker, F; Rübben, H | 1 |
| Arimoto, T; Inada, T; Kitagawa, Y; Koiso, K; Miyanaga, N; Noguchi, R; Ohtani, M; Tanaka, Y; Tsuji, H; Tsujii, H | 1 |
| Fukushima, S; Hasegawa, R; Sano, M; Shibata, MA; Shirai, T | 1 |
| Fukushima, S; Hagiwara, A; Kagawa, M; Kawabe, M; Shibata, MA | 1 |
| Asamoto, M; de Camargo, JL; Fukushima, S; Kato, T; Shirai, T | 1 |
| Fukushima, S; Hayashi, Y; Hosono, M; Makino, S; Mori, S; Murai, T; Ohara, T; Takeda, R; Takeuchi, Y | 1 |
| Aso, Y; Homma, Y; Kakizoe, T; Kondo, Y; Nagase, S | 1 |
| Drouin, G; Krinsky, NI; Lausen, N; Mathews-Roth, MM; Richter, A | 1 |
| Kakizoe, T; Kushida, H; Nagao, M; Sone, H; Sugimura, T; Sugiyama, K; Suzuki, M; Wakabayashi, K | 1 |
| Fukushima, S; Hagiwara, A; Okada, M; Shirai, T; Suzuki, E; Tamano, S | 1 |
| Saito, B | 1 |
| Akaza, H; Aso, Y; Koiso, K; Matsuki, K; Matsushima, H | 1 |
| Hagiwara, A; Hayashi, Y; Hosono, M; Kurata, Y; Makino, S; Mori, S; Murai, T; Ohhara, T; Shibata, MA; Takeuchi, Y | 1 |
| Yang, DA | 1 |
| Iguchi, M; Ishikawa, Y; Kataoka, K; Katayama, Y; Kodama, M; Kohri, K; Kurita, T; Takada, M; Takamura, C; Umekawa, T | 1 |
| Kawada, Y; Kobayashi, S; Kuriyama, M; Mori, H; Ohno, T; Takeuchi, T; Tanaka, T; Yamamoto, N | 1 |
| Kurita, T; Matsuda, H; Nakanishi, A; Tsujihashi, H; Uejima, S | 1 |
| Fukushima, S; Ito, M; Okumura, M; Shirai, T; Tamano, S; Yamada, S | 1 |
| Chappel, CI; Cohen, SM; Ellwein, LB; Johansson, SL; Khachab, M; Masui, T; Okamura, T; Schoenig, GP; Smith, RA; Wehner, JM | 1 |
| Asamoto, M; Fukushima, S; Ogiso, T; Okumura, M; Shirai, T | 1 |
| Asakawa, E; Fukushima, S; Hagiwara, A; Ogiso, T; Tamano, S | 1 |
| Asakawa, M; Hato, F; Kimura, S; Kinoshita, Y; Kishimoto, T; Maekawa, M; Nishijima, T; Wada, S | 1 |
| Kakinuma, H; Momose, H; Oyasu, R; Uchida, K; Yura, Y | 1 |
| Koyanagi, T; Ohashi, T; Saito, B; Togashi, M | 1 |
| Akiyama, T; Kurita, T; Matsuda, H; Tsujihashi, H; Uejima, S | 2 |
| Oyasu, R; Samma, S; Seidenfeld, J; Uchida, K | 1 |
| Nakagawa, S | 1 |
| Könnecke, B; Kunze, E; Nienaber, C | 1 |
| Babaya, K; Fujimoto, K; Hirao, Y; Momose, H; Okajima, E; Okamoto, S; Ozono, S; Sasaki, K; Tsumatani, K; Yamaguchi, H | 1 |
| Enomoto, T; Perantoni, AO; Ward, JM | 1 |
| Debiec-Rychter, M; Jones, RF; Wang, CY; Zukowski, K | 1 |
| Kashihara, N; Momose, H; Oyasu, R; Rademaker, A; Samma, S; Uchida, K | 1 |
| Fukushima, S; Hayashi, Y; Konishi, T; Kurata, Y; Makino, S; Mori, S; Murai, T; Takeuchi, Y; Toyama, M | 1 |
| Nagata, Y | 1 |
| Aso, Y; Hirai, M; Masuda, H; Ohtawara, Y; Tajima, A | 1 |
| Debruyne, FM; Herman, CJ; Ramaekers, FC; Vegt, PD; Vooijs, GP | 1 |
| Homma, Y; Oyasu, R; Ozono, S | 1 |
| Kakizoe, T; Niijima, T; Sato, S; Sekine, T; Takai, K | 1 |
| Fukushima, S; Inoue, K; Kakizoe, T; Ohtaguro, K; Ohtani, M; Okamura, T | 1 |
| Homma, Y; Kakizoe, T; Oyasu, R; Samma, S | 2 |
| Oyasu, R; Rademaker, A; Seidenfeld, J; Uchida, K | 1 |
| Akaza, H; Aso, Y; Kameyama, S; Matsuki, K; Munakata, A | 1 |
| Lina, BA; Woutersen, RA | 1 |
| Diwan, BA; Hagiwara, A; Rice, JM; Ward, JM | 1 |
| Fukushima, S; Hasegawa, R; Ito, N | 1 |
| Recker, F; Rübben, H | 1 |
| Hamami, G; Kamidono, S; Morishita, S | 1 |
| Imai, K; Suzuki, K; Suzuki, T; Takezawa, Y; Tsuji, H; Yamanaka, H | 1 |
| Yamashita, T | 1 |
| Kobayashi, Y | 1 |
| Deutz, FJ; Hofstädter, F; Küpper, W; Rübben, H | 1 |
| Campbell, P; Irving, CC; Lindahl, R | 1 |
| Fukushima, S; Hirose, M; Ito, N; Kurata, Y; Shibata, MA; Tamano, S | 1 |
| Debiec-Rychter, M; Wang, CY; Zukowski, K | 1 |
| Fukushima, S; Hagiwara, A; Ono, S; Shibata, MA; Tamano, S | 1 |
| Asakawa, M | 1 |
| Shi, BY | 2 |
| Fukushima, S; Ito, N; Kurata, Y; Thamavit, W | 1 |
| Berger, MR; Schmähl, D | 1 |
| Fukushima, S; Inoue, K; Ito, N; Ohtaguro, K; Okamura, T | 1 |
| Hayashi, Y; Maekawa, A; Nagase, S; Shumiya, S; Takahashi, M | 2 |
| Kawahara, M; Matsuhashi, T; Matsushima, M; Tajima, M; Yagishita, T | 1 |
| Hashimura, T; Kanamaru, H; Yoshida, O | 1 |
| Daniel, DS; Irving, CC | 1 |
| Hashimoto, Y; Masuko, T; Nakajima, S; Sugahara, K | 1 |
| Aoki, T; Fukushima, S; Inoue, T; Ito, N; Mera, Y; Tatematsu, M | 1 |
| Kawano, S; Ogata, J; Sakamoto, S; Yano, S | 1 |
| Fukushima, S; Imaida, K; Ito, N; Nagase, S; Nakanowatari, J | 1 |
| Okamura, T | 1 |
| Hirano, T; Ito, T; Koyanagi, T; Matsui, S; Ohashi, N; Ohashi, T; Shiba, T; Yamada, T; Yoshiki, T | 2 |
| Akiya, T; Chikenji, M; Katayama, T; Matsushita, T; Nakada, T; Ota, K; Saito, H | 1 |
| Elashoff, RM; Fears, TR; Schneiderman, MA | 1 |
| Fukushima, S; Masui, T; Mutai, M; Shirai, T; Takahashi, S | 1 |
| Hirao, Y; Iwata, H; Matsuki, H; Okajima, E; Ozono, S; Sasaki, K; Takahashi, S; Tsunemi, K | 1 |
| Babaya, K; Hirao, Y; Momose, H; Okajima, E; Ozono, S; Samma, S | 1 |
| Fukuoka, M; Hasegawa, R; Hayashi, Y; Morimoto, K; Tanaka, A | 1 |
| Deutz, FJ; Homburg, A; Lutzeyer, W; Recker, F; Rübben, H; Sieberth, HG | 1 |
| Fujita, J; Ito, N; Kitamura, Y; Nakayama, H; Ohuchi, N; Reynolds, SH; Yoshida, O | 1 |
| Bryan, GT; el-Aaser, AA; el-Merzabani, MM; Ertürk, E; Higgy, NA; Oberley, TD; Verma, AK | 1 |
| Fukushima, S; Imaida, K; Masui, T; Shirai, T; Uwagawa, S | 1 |
| Fukushima, S; Harauchi, T; Kurata, Y; Makino, S; Mori, S; Takeuchi, Y; Toyama, M | 1 |
| Fukushima, S; Imaida, K; Inoue, T; Okada, M; Suzuki, E | 1 |
| Akagi, A; Otsuka, H | 1 |
| Kawano, S; Mimata, H; Ogata, J; Shimada, T; Takeshita, M | 1 |
| Babaya, K; Hirao, Y; Matsuki, H; Momose, H; Okajima, E; Ozono, S; Samma, S; Sasaki, K; Takahashi, S | 1 |
| Fukushima, S; Ito, N; Okada, M; Shibata, M; Suzuki, E; Tamano, S | 1 |
| Goldstein, AL; Kimura, S; Kinoshita, Y; Maekawa, M; Nishio, S; Ozaki, Y; Toyokawa, T | 1 |
| Ozaki, Y | 1 |
| Kimura, S; Kinoshita, Y; Maekawa, M; Nishio, S; Ozaki, Y; Wada, S | 2 |
| Fukushima, S; Kurata, Y; Makino, S; Mori, S; Takeuchi, Y; Toyama, M | 1 |
| Fukushima, S; Hirose, M; Ito, N; Shirai, T; Tamano, S | 1 |
| Honda, M | 1 |
| Aota, Y | 1 |
| Airoldi, L; Bonfanti, M; Fanelli, R; Magagnotti, C | 1 |
| Graewe, T; Kunze, E; Rath, G | 1 |
| Fukushima, S; Imaida, K; Kurata, Y; Shibata, M; Shirai, T; Tamano, S | 1 |
| Hisazumi, H; Koshida, K; Kumaki, O; Misaki, T; Miyoshi, N; Nakajima, K; Uchibayashi, T; Ueki, O | 1 |
| Fukushima, S; Imaida, K; Ito, N; Shirai, T; Tagawa, Y | 1 |
| Cui, W; Fan, XJ; Ha, XW; Lin, PZ; Okada, M; Shen, H; Xie, JG; Zhang, JS | 1 |
| Asamoto, M; Fukushima, S; Hagiwara, A; Kurata, Y; Masui, T | 1 |
| Fukushima, S; Kakizoe, T; Ohtani, M; Sato, S; Sugimura, T | 1 |
| Ito, N; Masui, T; Miyata, Y; Nakanishi, K; Shibata, M; Shibata, MA | 1 |
| Bauer, K; Homma, Y; Oyasu, R; Ozono, S; Samma, S; Wallemark, CB | 1 |
| Fukushima, S; Hirose, M; Ito, N; Kurata, Y; Ogiso, T | 1 |
| Babaya, K; Hirao, Y; Okajima, E; Ozono, S; Sanma, S; Sasaki, K | 1 |
| Chowaniec, J; Chrysostomou, E; Gwynne, J; Hicks, RM; Nandra, K; Pedrick, M; Tomlinson, CN; Turton, JA | 1 |
| Hiasa, Y; Kitahori, Y; Konishi, N; Miyashiro, A; Shimoyama, T | 1 |
| Hoffmann, D; La Voie, EJ; Mu, B; Rivenson, A; Shigematsu, A | 1 |
| Babaya, K; Hirao, Y; Matsuki, H; Moriya, A; Nakatsuji, F; Okajima, E; Samma, S; Tabata, S; Watanabe, S; Yoshie, T | 1 |
| Hiasa, Y; Kitahori, Y; Konishi, N; Shimoyama, T | 1 |
| Fukushima, S; Inoue, K; Ito, N; Kurata, Y; Tamano, S | 1 |
| Fukushima, S; Hirose, M; Ito, N; Masui, T; Miyata, Y | 1 |
| Kakizoe, T; Niijima, T; Nishio, Y; Ohtani, M; Sato, S; Sugimura, T | 1 |
| Fukushima, S; Ito, N; Shibata, MA; Shirai, T; Tamano, S | 1 |
| Fukushima, S; Kakizoe, T; Niijima, T; Nishio, Y; Ohtani, M; Sato, S; Sugimura, T | 1 |
| Anderson, RL; Francis, WR; Kanerva, RL; Lefever, FR | 1 |
| Nagai, N | 1 |
| Fukushima, S; Ito, N; Kurata, Y; Miyata, Y; Ogiso, T; Okuda, M | 1 |
| Leary, SL; Quander, RV; Squire, RA; Strandberg, JD; Yarbrough, BA | 1 |
10 review(s) available for butylhydroxybutylnitrosamine and Bladder Cancer
| Article | Year |
|---|---|
The N-butyl-N-4-hydroxybutyl Nitrosamine Mouse Urinary Bladder Cancer Model.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; FANFT; Humans; Mice; Mice, Transgenic; Urinary Bladder Neoplasms | 2018 |
The role of the androgen receptor in the development and progression of bladder cancer.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Castration; Disease Models, Animal; Disease Progression; Evidence-Based Medicine; Female; Gene Expression Regulation, Neoplastic; Humans; Incidence; Male; Neoplasms, Hormone-Dependent; Receptors, Androgen; Risk Factors; Sex Factors; Signal Transduction; Urinary Bladder Neoplasms | 2012 |
The scientific basis for regarding vitamin A and its analogues as anti-carcinogenic agents.
Topics: Animals; Antineoplastic Agents; beta Carotene; Butylhydroxybutylnitrosamine; Carcinoma in Situ; Carcinoma, Papillary; Carotenoids; Cell Differentiation; Dose-Response Relationship, Drug; Epithelium; Fenretinide; Humans; Isotretinoin; Neoplasms; Neoplasms, Experimental; Tretinoin; Urinary Bladder Neoplasms; Vitamin A | 1983 |
The canopic worm: role of bilharziasis in the aetiology of human bladder cancer.
Topics: Animals; Bacterial Infections; Butylhydroxybutylnitrosamine; Child; Egypt; Female; Humans; Male; Nitrosamines; Papio; Schistosoma haematobium; Schistosomiasis; Sex Factors; Urinary Bladder Neoplasms; Urinary Tract Infections | 1983 |
[Effect of BBN on the small intestine transplanted to the urinary bladder of rat].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Female; Intestine, Small; Rats; Rats, Wistar; Transplantation, Heterotopic; Urinary Bladder; Urinary Bladder Neoplasms; Urinary Diversion | 1995 |
New strategy of bio-chemoprevention on recurrence of superficial bladder cancer based on a hypothesis of the mechanism of recurrence.
Topics: Administration, Intravesical; Animals; BCG Vaccine; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Cytosine; Humans; Interferon Inducers; Mice; Multicenter Studies as Topic; Neoplasm Recurrence, Local; Rats; Urinary Bladder Neoplasms | 1997 |
[Structure and metabolic fate of N-nitrosodialkylamines in relation to their organotropic carcinogenicity with special reference to induction of urinary bladder tumors].
Topics: Animals; Biotransformation; Butylhydroxybutylnitrosamine; Cricetinae; Dogs; Guinea Pigs; Mice; Nitrosamines; Organ Specificity; Rats; Species Specificity; Urinary Bladder Neoplasms | 1997 |
[Experimental replication of bladder tumors. Morphologic features of early stages of their development].
Topics: 2-Acetylaminofluorene; 2-Naphthylamine; Animals; Butylhydroxybutylnitrosamine; Cell Membrane; Cell Transformation, Neoplastic; DNA, Neoplasm; Epithelium; FANFT; Humans; Hyperplasia; Methylcholanthrene; Methylnitrosourea; Mice; Microscopy, Electron; Naphthalenes; Neoplasms, Experimental; Papilloma; Rats; Schistosoma haematobium; Species Specificity; Sulfonamides; Urinary Bladder Neoplasms | 1979 |
Modification of tumor development in the urinary bladder.
Topics: Animals; Antineoplastic Agents; Antioxidants; Butylhydroxybutylnitrosamine; Cocarcinogenesis; FANFT; Methylnitrosourea; Precancerous Conditions; Urinary Bladder Neoplasms | 1991 |
Significance of L-ascorbic acid and urinary electrolytes in promotion of rat bladder carcinogenesis.
Topics: Animals; Ascorbic Acid; Bicarbonates; Butylhydroxybutylnitrosamine; Carbonates; Electrolytes; Hydrogen-Ion Concentration; Male; Potassium; Rats; Rats, Inbred F344; Sodium; Sodium Bicarbonate; Urinary Bladder Neoplasms; Urine | 1985 |
1 trial(s) available for butylhydroxybutylnitrosamine and Bladder Cancer
| Article | Year |
|---|---|
Deletion of leucine zipper tumor suppressor 2 (Lzts2) increases susceptibility to tumor development.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cell Cycle Proteins; DNA-Binding Proteins; Female; Gene Deletion; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; HEK293 Cells; Heterozygote; Humans; Male; Mice; Mice, Knockout; Prostatic Neoplasms; Tumor Suppressor Proteins; Urinary Bladder Neoplasms | 2013 |
486 other study(ies) available for butylhydroxybutylnitrosamine and Bladder Cancer
| Article | Year |
|---|---|
Metabolomic credentialing of murine carcinogen-induced urothelial cancer.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cell Line; Humans; Male; Metabolome; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Urinary Bladder Neoplasms; Urothelium | 2021 |
Sex differences in the aging murine urinary bladder and influence on the tumor immune microenvironment of a carcinogen-induced model of bladder cancer.
Topics: Aging; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Female; Humans; Male; Mice; Sex Characteristics; Tumor Microenvironment; Urinary Bladder; Urinary Bladder Neoplasms | 2022 |
The carbonic anhydrase inhibitor acetazolamide inhibits urinary bladder cancers via suppression of β-catenin signaling.
Topics: Acetazolamide; Animals; beta Catenin; Butylhydroxybutylnitrosamine; Carbonic Anhydrase Inhibitors; Carcinoma, Transitional Cell; Humans; Male; Mice; Rats; Urinary Bladder Neoplasms | 2022 |
Persistent γ-H2AX Formation and Expression of Stem Cell Markers in N-Butyl-N-(4-Hydroxybutyl)Nitrosamine-Induced Bladder Carcinogenesis in Rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenesis; Histones; Hyperplasia; Inflammation; Nitrosamines; Phosphoproteins; Rats; Stem Cells; Urinary Bladder; Urinary Bladder Neoplasms | 2022 |
Promotion effects of acetoaceto-o-toluidide on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder carcinogenesis in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Carcinogens; Cyclooxygenase 2; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Male; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins c-jun; Rats, Inbred F344; Real-Time Polymerase Chain Reaction; Toluidines; Urinary Bladder; Urinary Bladder Neoplasms | 2019 |
The dynamics of the inflammatory response during BBN-induced bladder carcinogenesis in mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenesis; Gene Expression Regulation, Neoplastic; Inflammation; Male; Mice, Inbred C57BL; Urinary Bladder Neoplasms | 2019 |
Combination of Erlotinib and Naproxen Employing Pulsatile or Intermittent Dosing Profoundly Inhibits Urinary Bladder Cancers.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Disease Progression; Drug Administration Schedule; Drug Therapy, Combination; ErbB Receptors; Erlotinib Hydrochloride; Female; Humans; Naproxen; Neoplasm Recurrence, Local; Neoplasms, Experimental; Pulse Therapy, Drug; Rats; Time Factors; Time-to-Treatment; Urinary Bladder; Urinary Bladder Neoplasms | 2020 |
Enhanced Efficacy of PEGylated Liposomal Cisplatin: In Vitro and In Vivo Evaluation.
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Liberation; Female; Humans; Liposomes; Microscopy, Electron, Scanning; Particle Size; Polyethylene Glycols; Rats, Wistar; Treatment Outcome; Tumor Burden; Urinary Bladder Neoplasms | 2020 |
Luteolin suppresses bladder cancer growth via regulation of mechanistic target of rapamycin pathway.
Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Cell Line, Tumor; Cell Proliferation; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Ki-67 Antigen; Luteolin; Male; Mice; Proto-Oncogene Proteins c-akt; Rats; rho GTP-Binding Proteins; Signal Transduction; Thioredoxins; TOR Serine-Threonine Kinases; Urinary Bladder Neoplasms; Xenograft Model Antitumor Assays | 2020 |
Dose dependency of γ-H2AX formation in the rat urinary bladder treated with genotoxic and nongenotoxic bladder carcinogens.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; DNA Damage; Dose-Response Relationship, Drug; Histones; Male; Models, Animal; Phosphoproteins; Rats; Rats, Inbred F344; Triazines; Urinary Bladder Neoplasms | 2020 |
Alterations in detrusor contractility in rat model of bladder cancer.
Topics: Animals; Butylhydroxybutylnitrosamine; Disease Models, Animal; Male; Muscle Contraction; Rats; Rats, Wistar; TRPV Cation Channels; Urinary Bladder; Urinary Bladder Neoplasms; Urinary Incontinence | 2020 |
Chemopreventive Potential of Myrtenal against Nitrosamine-Initiated, Radiation-Promoted Rat Bladder Carcinogenesis.
Topics: Animals; Bicyclic Monoterpenes; Butylhydroxybutylnitrosamine; Carcinogenesis; Carcinogens; Nitrosamines; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 2022 |
BBN-driven urinary bladder cancer mouse model.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenesis; Carcinogens; Mice; Mutation; Urinary Bladder Neoplasms | 2021 |
mRNA translation is a therapeutic vulnerability necessary for bladder epithelial transformation.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; Drug Screening Assays, Antitumor; Eukaryotic Initiation Factor-4E; Gene Knock-In Techniques; Homeostasis; Humans; Mice; Neoplasm Transplantation; Protein Biosynthesis; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Ribosomal Proteins; RNA, Messenger; Urinary Bladder Neoplasms; Urothelium | 2021 |
Ultrastructural immunohistochemical study of L-type amino acid transporter 1-4F2 heavy chain in tumor microvasculatures of N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) induced rat bladder carcinoma.
Topics: Animals; Butylhydroxybutylnitrosamine; Fusion Regulatory Protein 1, Heavy Chain; Immunohistochemistry; Large Neutral Amino Acid-Transporter 1; Male; Microscopy, Electron; Microvessels; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 2017 |
Topical and systemic immunoreaction triggered by intravesical chemotherapy in an N-butyl-N-(4-hydroxybutyl) nitorosamine induced bladder cancer mouse model.
Topics: Adjuvants, Immunologic; Administration, Intravesical; Animals; Antineoplastic Combined Chemotherapy Protocols; Butylhydroxybutylnitrosamine; Cytokines; Deoxycytidine; Doxorubicin; Female; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Mice; Mitomycin; Neoplasms, Experimental; Treatment Outcome; Urinary Bladder Neoplasms | 2017 |
The interaction of arsenic and N-butyl-N-(4-hydroxybutyl)nitrosamine on urothelial carcinogenesis in mice.
Topics: Animals; Arsenic; Butylhydroxybutylnitrosamine; Carcinogenesis; Carcinogens; Carcinoma, Transitional Cell; Carrier Proteins; Cyclin-Dependent Kinase Inhibitor p21; Drug Interactions; Female; Gene Expression Regulation, Neoplastic; Glutathione Transferase; Male; Mice; Mice, Inbred C57BL; NAD(P)H Dehydrogenase (Quinone); Sp1 Transcription Factor; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium | 2017 |
Biodistribution of gold nanoparticles in BBN-induced muscle-invasive bladder cancer in mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Gold; Metal Nanoparticles; Mice, Inbred C57BL; Muscles; Tissue Distribution; Urinary Bladder Neoplasms | 2017 |
Immuno-PET imaging of tumor-infiltrating lymphocytes using zirconium-89 radiolabeled anti-CD3 antibody in immune-competent mice bearing syngeneic tumors.
Topics: Animals; Antibodies; Butylhydroxybutylnitrosamine; CD3 Complex; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Deferoxamine; Flow Cytometry; Lymphocytes, Tumor-Infiltrating; Mice, Inbred C57BL; Neoplasm Transplantation; Positron Emission Tomography Computed Tomography; Radioisotopes; Radiopharmaceuticals; Tissue Distribution; Urinary Bladder Neoplasms; Zirconium | 2018 |
FGFR3 mutation increases bladder tumourigenesis by suppressing acute inflammation.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Transformation, Neoplastic; Cholecystitis, Acute; Disease Models, Animal; Disease Progression; Female; Genetic Predisposition to Disease; Lymphocytes; Male; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Neutrophil Infiltration; Neutrophils; Phenotype; Receptor, Fibroblast Growth Factor, Type 3; Time Factors; Tumor Microenvironment; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium | 2018 |
Sulforaphane Normalizes Intestinal Flora and Enhances Gut Barrier in Mice with BBN-Induced Bladder Cancer.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Butyric Acid; Caco-2 Cells; Gastrointestinal Microbiome; Humans; Immunoglobulin A, Secretory; Interleukin-6; Isothiocyanates; Male; Mice, Inbred C57BL; Sulfoxides; Tight Junction Proteins; Urinary Bladder Neoplasms | 2018 |
Elucidating the role of Agl in bladder carcinogenesis by generation and characterization of genetically engineered mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Genetic Engineering; Glycogen Debranching Enzyme System; Mice; Mice, Inbred C57BL; Mice, Knockout; Sequence Analysis, RNA; Urinary Bladder Neoplasms | 2019 |
Intravesical treatment of chemotherapeutic agents sensitizes bacillus Calmette‑Guerin by the modulation of the tumor immune environment.
Topics: Administration, Intravesical; Animals; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Disease Progression; Doxorubicin; Female; Humans; Killer Cells, Natural; Macrophages; Mice, Inbred C57BL; Mitomycin; Neoplasm Recurrence, Local; Neoplasms, Experimental; T-Lymphocytes, Regulatory; Treatment Outcome; Tumor Microenvironment; Urinary Bladder; Urinary Bladder Neoplasms | 2019 |
A study in a rat initiation-promotion bladder tumour model demonstrated no promoter/progressor potential of dapagliflozin.
Topics: Administration, Oral; Animals; Benzhydryl Compounds; Butylhydroxybutylnitrosamine; Disease Models, Animal; Dose-Response Relationship, Drug; Glucosides; Male; Rats; Rats, Sprague-Dawley; Urinary Bladder Neoplasms | 2019 |
Decreased tumorigenesis and mortality from bladder cancer in mice lacking urothelial androgen receptor.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenesis; Cell Transformation, Neoplastic; Curcumin; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; DNA Repair; Humans; Mice; Models, Biological; Proliferating Cell Nuclear Antigen; Proteolysis; Receptors, Androgen; Survival Analysis; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms; Urothelium | 2013 |
E-cadherin and β-catenin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in mice.
Topics: Animals; beta Catenin; Butylhydroxybutylnitrosamine; Cadherins; Carcinogenesis; Cell Adhesion; Cytoplasm; Disease Progression; Gene Expression Regulation, Neoplastic; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Phenotype; Prognosis; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium | 2013 |
Meloxicam in the treatment of in vitro and in vivo models of urinary bladder cancer.
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Cell Cycle Checkpoints; Cell Proliferation; Comet Assay; Cyclooxygenase Inhibitors; DNA Damage; Flow Cytometry; Humans; Injections, Intraperitoneal; Male; Meloxicam; Mice; Mice, Inbred ICR; Microscopy; Neoplasms, Experimental; Precancerous Conditions; Thiazines; Thiazoles; Urinary Bladder Neoplasms | 2013 |
Cytogenetic characterization of an N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse papillary urothelial carcinoma.
Topics: Abnormal Karyotype; Animals; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Chromosome Banding; Male; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Tetraploidy; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium | 2013 |
[Long-term anti-cancer implants inhibiting the activity of tumor growth in animal models].
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Delayed-Action Preparations; Disease Models, Animal; Doxorubicin; Female; Implants, Experimental; Polyanhydrides; Rats; Rats, Sprague-Dawley; Urinary Bladder Neoplasms | 2013 |
Epidermal growth factor enhances androgen receptor‑mediated bladder cancer progression and invasion via potentiation of AR transactivation.
Topics: Androgens; Animals; Butylhydroxybutylnitrosamine; Carcinogenesis; Castration; Disease Models, Animal; Disease Progression; Epidermal Growth Factor; ErbB Receptors; Humans; Male; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphatidylinositol 3-Kinases; Quinazolines; Receptors, Androgen; Signal Transduction; Transcriptional Activation; Urinary Bladder Neoplasms | 2013 |
Suppression of ERβ signaling via ERβ knockout or antagonist protects against bladder cancer development.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cell Line, Tumor; DNA Replication; Estrogen Receptor beta; Female; Humans; Mice; Mice, Knockout; Signal Transduction; Urinary Bladder Neoplasms | 2014 |
Induction of invasive transitional cell bladder carcinoma in immune intact human MUC1 transgenic mice: a model for immunotherapy development.
Topics: Animals; Butylhydroxybutylnitrosamine; Cancer Vaccines; Carcinogens; Carcinoma, Transitional Cell; Cytokines; Disease Models, Animal; Female; Humans; Immunotherapy; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mucin-1; T-Lymphocytes, Cytotoxic; Urinary Bladder Neoplasms | 2013 |
Nanoparticulation of BCG-CWS for application to bladder cancer therapy.
Topics: Adult; Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Cell Differentiation; Cell Line, Tumor; Cell Wall Skeleton; Cells, Cultured; Female; Humans; Male; Mice; Mice, Inbred C3H; Mycobacterium bovis; Nanoparticles; Rats; Rats, Inbred F344; T-Lymphocytes; Urinary Bladder Neoplasms; Young Adult | 2014 |
Commentary on "tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl) nitrosamine as the basis for urothelial cell carcinogenesis." He Z, Kosinska W, Zhao ZL, Wu XR, Guttenplan JB, Department of Basic Science, New York University Dental College, NY, US
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Environmental Pollutants; Female; Male; Mutagens; Urinary Bladder Neoplasms; Urothelium | 2014 |
Molecular insights into mitochondrial dysfunction in cancer-related muscle wasting.
Topics: Adenosine Triphosphate; Animals; Apoptosis; Butylhydroxybutylnitrosamine; Energy Metabolism; Humans; Ion Channels; Lipid Peroxidation; Mitochondria; Mitochondrial Proteins; Muscle, Skeletal; Muscular Atrophy; Oxidative Stress; Uncoupling Protein 3; Urinary Bladder Neoplasms | 2014 |
Cellular origin of bladder neoplasia and tissue dynamics of its progression to invasive carcinoma.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; Cell Lineage; Cell Proliferation; Cell Transformation, Neoplastic; Disease Models, Animal; Genotype; Hedgehog Proteins; Humans; Male; Mice; Mice, Transgenic; Neoplasm Invasiveness; Neoplastic Stem Cells; Phenotype; Recombinant Fusion Proteins; Time Factors; Tumor Burden; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium | 2014 |
Anticancer benefits of early versus late use of rapamycin in a rat model of urothelial carcinoma.
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Drug Administration Schedule; Male; Neoplasm Grading; Neoplasms, Experimental; Rats, Inbred F344; Sirolimus; Time Factors; Tumor Burden; Urinary Bladder Neoplasms; Urothelium | 2014 |
Cationic core-shell nanoparticles for intravesical chemotherapy in tumor-induced rat model: safety and efficacy.
Topics: Administration, Intravesical; Animals; Antibiotics, Antineoplastic; Butylhydroxybutylnitrosamine; Cations; Chitosan; Disease-Free Survival; Drug Carriers; Kaplan-Meier Estimate; Male; Mitomycin; Nanoparticles; Polyesters; Rats, Sprague-Dawley; Urinary Bladder; Urinary Bladder Neoplasms | 2014 |
Vascular endothelial growth factor mRNA levels as a biomarker for short-term N-butyl-N-(4-hydroxybutyl) nitrosamine-induced rat bladder carcinogenesis bioassay.
Topics: Animals; Biological Assay; Biomarkers; Butylhydroxybutylnitrosamine; Carcinogens; Hyperplasia; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A | 2015 |
Downregulation of glutathione S-transferase M1 protein in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced mouse bladder carcinogenesis.
Topics: Animals; Antimetabolites, Antineoplastic; Azacitidine; Blotting, Western; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Cell Line, Tumor; Coloring Agents; Decitabine; Down-Regulation; Electrophoresis, Gel, Two-Dimensional; Female; Glutathione Transferase; Humans; Immunohistochemistry; Mice; Mice, Inbred C57BL; Mucous Membrane; Real-Time Polymerase Chain Reaction; RNA, Messenger; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Urinary Bladder; Urinary Bladder Neoplasms | 2014 |
EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype.
Topics: Adult; Aged; Aged, 80 and over; Animals; Autocrine Communication; Butylhydroxybutylnitrosamine; Cell Line, Tumor; Cell Proliferation; ErbB Receptors; Female; Gene Expression Regulation, Neoplastic; Hepatocyte Nuclear Factor 3-alpha; Humans; Keratins; Male; Mice; Middle Aged; Molecular Targeted Therapy; Muscles; Neoplasm Invasiveness; Phenotype; Protein Kinase Inhibitors; Signal Transduction; Survival Analysis; Transcriptome; Treatment Outcome; Urinary Bladder Neoplasms | 2014 |
Bladder cancers arise from distinct urothelial sub-populations.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma in Situ; Carcinoma, Papillary; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cell Lineage; Female; Humans; Keratin-5; Luminescent Proteins; Male; Mice, 129 Strain; Mice, Knockout; Mice, Transgenic; Microscopy, Confocal; Neoplastic Stem Cells; Urinary Bladder Neoplasms | 2014 |
Suppressive Effect of Matrine on Tumor Invasion in N-Butyl-N-(4-Hydroxybutyl)Nitrosamine-Induced Urinary Bladder Carcinogenesis.
Topics: Alkaloids; Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Male; Matrines; Neoplasm Invasiveness; Quinolizines; Rats; Rats, Sprague-Dawley; Treatment Outcome; Urinary Bladder Neoplasms | 2014 |
Prevention of chemically induced urinary bladder cancers by naproxen: protocols to reduce gastric toxicity in humans do not alter preventive efficacy.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Blotting, Western; Butylhydroxybutylnitrosamine; Carcinogens; Female; Fluorescent Antibody Technique; Humans; Mice; Naproxen; Rats; Rats, Inbred F344; Stomach; Urinary Bladder Neoplasms | 2015 |
Ethanol-extracted propolis enhances BBN-initiated urinary bladder carcinogenesis via non-mutagenic mechanisms in rats.
Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Cell Proliferation; Cocarcinogenesis; Dietary Supplements; Dose-Response Relationship, Drug; Ethanol; Gene Expression Regulation; Gene Expression Regulation, Neoplastic; Male; Plant Extracts; Precancerous Conditions; Propolis; Random Allocation; Rats, Inbred F344; Rats, Mutant Strains; Solvents; Urinary Bladder; Urinary Bladder Neoplasms | 2015 |
Antiproliferative and anti-inflammatory properties of diindolylmethane and lupeol against N-butyl-N-(4-hydroxybutyl) nitrosamine induced bladder carcinogenesis in experimental rats.
Topics: Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Butylhydroxybutylnitrosamine; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Indoles; Male; Nuclear Proteins; Pentacyclic Triterpenes; PTEN Phosphohydrolase; Rats, Wistar; Urinary Bladder Neoplasms | 2016 |
The effects of early versus delayed castration targeting androgen on prolonging survival in a mouse model of bladder cancer.
Topics: Androgens; Animals; Apoptosis; Butylhydroxybutylnitrosamine; Cell Proliferation; Disease Models, Animal; Male; Mice; Orchiectomy; Receptors, Androgen; Time Factors; Treatment Outcome; Urinary Bladder Neoplasms | 2015 |
Knockout of phospholipase Cε attenuates N-butyl-N-(4-hydroxybutyl) nitrosamine-induced bladder tumorigenesis.
Topics: Animals; Blotting, Western; Butylhydroxybutylnitrosamine; Carcinogenesis; Cyclooxygenase 2; Fluorescent Antibody Technique; Inflammation; Mice, Inbred C57BL; Mice, Knockout; Neovascularization, Pathologic; Phosphoinositide Phospholipase C; Urinary Bladder; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A | 2016 |
Conditional Expression of the Androgen Receptor Increases Susceptibility of Bladder Cancer in Mice.
Topics: Androgens; Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Cell Transformation, Neoplastic; Drug Implants; Female; Genetic Predisposition to Disease; Humans; Integrases; Male; Mice; Mice, Transgenic; Neoplasms, Hormone-Dependent; Orchiectomy; Promoter Regions, Genetic; Receptors, Androgen; Recombinant Fusion Proteins; Tamoxifen; Testosterone; Transgenes; Urinary Bladder Neoplasms; Uroplakin III | 2016 |
DNA cytophotometric and histological analysis of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced precancerous lesions of the bladder urothelium.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; DNA; Female; Precancerous Conditions; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 2016 |
Diindolylmethane and Lupeol Modulates Apoptosis and Cell Proliferation in N-Butyl-N-(4-Hydroxybutyl) Nitrosamine Initiated and Dimethylarsinic Acid Promoted rat Bladder Carcinogenesis.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Butylhydroxybutylnitrosamine; Cacodylic Acid; Carcinogenesis; Carcinogens; Caspase 3; Caspase 9; Cell Proliferation; Indoles; Male; Pentacyclic Triterpenes; Proliferating Cell Nuclear Antigen; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms | 2016 |
Targeting estrogen/estrogen receptor alpha enhances Bacillus Calmette-Guérin efficacy in bladder cancer.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; BCG Vaccine; Butylhydroxybutylnitrosamine; Cell Line, Tumor; Cell Movement; Cell Proliferation; Drug Synergism; Estradiol; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Female; Fulvestrant; Humans; Integrin alpha5beta1; Interleukin-6; Macrophages; Mice; Neoplasms, Experimental; Treatment Outcome; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms | 2016 |
[Karyometry of BBN-induced precancerosis of the urothelium : An experimental analysis].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Disease Models, Animal; Karyometry; Precancerous Conditions; Rats; Rats, Wistar; Reproducibility of Results; Sensitivity and Specificity; Urinary Bladder Neoplasms; Urothelium | 2016 |
RGS6 is an essential tumor suppressor that prevents bladder carcinogenesis by promoting p53 activation and DNMT1 downregulation.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Transformation, Neoplastic; DNA (Cytosine-5-)-Methyltransferase 1; Gene Expression; Humans; Mice, Inbred C57BL; Mice, Knockout; RGS Proteins; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium | 2016 |
Chemopreventive effect of omega-3 polyunsaturated fatty acids and atorvastatin in rats with bladder cancer.
Topics: Animals; Apoptosis; Atorvastatin; Butylhydroxybutylnitrosamine; Cell Proliferation; Docosahexaenoic Acids; Eicosapentaenoic Acid; Male; Oxidative Stress; Random Allocation; Rats; Urinary Bladder Neoplasms | 2017 |
Molecular credentialing of rodent bladder carcinogenesis models.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Disease Models, Animal; Disease Progression; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Invasiveness; Oligonucleotide Array Sequence Analysis; Rats; Urinary Bladder Neoplasms | 2008 |
Rosiglitazone, a PPAR gamma agonist: potent promoter of hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Female; Immunohistochemistry; PPAR gamma; Rats; Rats, Inbred F344; Rosiglitazone; Thiazolidinediones; Urinary Bladder Neoplasms | 2008 |
Inhibitory effects of the aqueous extract of Magnolia officinalis on the responses of human urinary bladder cancer 5637 cells in vitro and mouse urinary bladder tumors induced by N-Butyl-N-(4-hydroxybutyl) nitrosamine in vivo.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; bcl-2-Associated X Protein; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cytochromes c; DNA; Dose-Response Relationship, Drug; Humans; Magnolia; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Nucleic Acid Synthesis Inhibitors; Plant Extracts; Urinary Bladder Neoplasms | 2009 |
Bladder outlet obstruction accelerates bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Female; Fibroblast Growth Factor 2; Hyperplasia; Hypoxia-Inducible Factor 1, alpha Subunit; Muscle, Smooth; Organ Size; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neck Obstruction; Urinary Bladder Neoplasms | 2009 |
DNA cytometry and kinetics of rat urothelial lesions during chemical carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Proliferation; Cell Transformation, Neoplastic; DNA, Neoplasm; Female; Ki-67 Antigen; Ploidies; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urothelium | 2009 |
Identification of differently expressed genes in chemical carcinogen-induced rat bladder cancers.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Male; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley; Urinary Bladder Neoplasms | 2009 |
Anti-tumor effect of cimetidine via inhibiting angiogenesis factors in N-butyl-N-(4-hydroxybutyl) nitrosamine-induced mouse and rat bladder carcinogenesis.
Topics: Angiogenesis Inhibitors; Angiogenic Proteins; Animals; Butylhydroxybutylnitrosamine; Cimetidine; Down-Regulation; E-Selectin; Immunohistochemistry; Male; Mice; Mice, Inbred BALB C; Neoplasm Staging; Rats; Rats, Wistar; Thymidine Phosphorylase; Time Factors; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A | 2009 |
The effects of sirolimus on urothelial lesions chemically induced in ICR mice by BBN.
Topics: Animals; Antibiotics, Antineoplastic; Butylhydroxybutylnitrosamine; Carcinoma in Situ; Carcinoma, Papillary; Hyperplasia; Immunoenzyme Techniques; Male; Mice; Mice, Inbred ICR; Sirolimus; Urinary Bladder Neoplasms | 2009 |
Suppression of AhR signaling pathway is associated with the down-regulation of UDP-glucuronosyltransferases during BBN-induced urinary bladder carcinogenesis in mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Cytochrome P-450 CYP1A1; Down-Regulation; Gene Expression Regulation, Neoplastic; Glucuronosyltransferase; Humans; Mice; Receptors, Aryl Hydrocarbon; RNA, Messenger; Signal Transduction; Time Factors; UDP-Glucuronosyltransferase 1A9; Urinary Bladder Neoplasms | 2010 |
Chemopreventive efficacy of naproxen and nitric oxide-naproxen in rodent models of colon, urinary bladder, and mammary cancers.
Topics: Alkylating Agents; Animals; Anti-Inflammatory Agents, Non-Steroidal; Azoxymethane; Butylhydroxybutylnitrosamine; Carcinogens; Colonic Neoplasms; Diet; Female; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Naproxen; Nitric Oxide Donors; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Urinary Bladder Neoplasms | 2009 |
Potential effects of the herbicide Diuron on mammary and urinary bladder two-stage carcinogenesis in a female Swiss mouse model.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Disease Models, Animal; Diuron; Dose-Response Relationship, Drug; Female; Herbicides; Immunohistochemistry; Mammary Glands, Animal; Mice; Random Allocation; Urinary Bladder Neoplasms | 2010 |
Fluorescent imaging of high-grade bladder cancer using a specific antagonist for chemokine receptor CXCR4.
Topics: Animals; Blotting, Western; Butylhydroxybutylnitrosamine; Carcinoma in Situ; Diagnostic Imaging; Humans; Immunoenzyme Techniques; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Peptide Fragments; Receptors, CXCR4; Spectrometry, Fluorescence; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms; Urine | 2010 |
Green tea polyphenol suppresses tumor invasion and angiogenesis in N-butyl-(-4-hydroxybutyl) nitrosamine-induced bladder cancer.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Butylhydroxybutylnitrosamine; Camellia sinensis; Female; Flavonoids; Mice; Neoplasm Invasiveness; Phenols; Plant Extracts; Polyphenols; Urinary Bladder Neoplasms | 2010 |
Inhibition of bladder tumour growth by sirolimus in an experimental carcinogenesis model.
Topics: Animals; Antibiotics, Antineoplastic; Butylhydroxybutylnitrosamine; Carcinogens; Caspase 3; Down-Regulation; Ki-67 Antigen; Male; Rats; Rats, Wistar; Sirolimus; Urinary Bladder; Urinary Bladder Neoplasms | 2011 |
Milk fat globule--epidermal growth factor--factor VIII (MFGE8)/lactadherin promotes bladder tumor development.
Topics: Animals; Antigens, Surface; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Cell Adhesion; Cell Transformation, Neoplastic; Gene Expression Profiling; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Milk Proteins; Neovascularization, Pathologic; T-Lymphocytes, Regulatory; Urinary Bladder Neoplasms | 2011 |
Altered expression of UPIa, UPIb, UPII, and UPIIIa during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Keratin-20; Male; Membrane Glycoproteins; Rats; Rats, Wistar; Urinary Bladder Neoplasms; Urothelium | 2011 |
Efficacy of the EGFr inhibitor Iressa on development of chemically-induced urinary bladder cancers: dose dependency and modulation of biomarkers.
Topics: Animals; Antineoplastic Agents; Biomarkers; Butylhydroxybutylnitrosamine; Cluster Analysis; ErbB Receptors; Female; Gefitinib; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Models, Biological; Quinazolines; Rats; Signal Transduction; Urinary Bladder Neoplasms | 2011 |
Paeonia lactiflora Pall inhibits bladder cancer growth involving phosphorylation of Chk2 in vitro and in vivo.
Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Butylhydroxybutylnitrosamine; Carcinoma; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Checkpoint Kinase 2; Disease Models, Animal; Drugs, Chinese Herbal; Humans; Male; Paeonia; Phosphorylation; Phytotherapy; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Urinary Bladder Neoplasms; Urothelium | 2011 |
Preventive but not curative efficacy of celecoxib on bladder carcinogenesis in a rat model.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Celecoxib; Cyclooxygenase 2 Inhibitors; Disease Models, Animal; Inflammation Mediators; Kidney; Liver; Male; Oxidation-Reduction; Pyrazoles; Rats; Rats, Wistar; Sulfonamides; Urinary Bladder Neoplasms | 2010 |
Experimental study of the anticancer effect of gemcitabine combined with sirolimus on chemically induced urothelial lesions.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Butylhydroxybutylnitrosamine; Deoxycytidine; Gemcitabine; Male; Mice; Mice, Inbred ICR; Neoplasm Invasiveness; Sirolimus; Survival Rate; Treatment Outcome; Urinary Bladder Neoplasms | 2011 |
The therapeutic effects of R8-liposome-BCG-CWS on BBN-induced rat urinary bladder carcinoma.
Topics: Animals; BCG Vaccine; Butylhydroxybutylnitrosamine; Cell Growth Processes; Cell Wall; Immunotherapy; Interferon-gamma; Liposomes; Male; Mycobacterium bovis; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 2011 |
Thioredoxin-interacting protein suppresses bladder carcinogenesis.
Topics: Aged; Animals; Blotting, Western; Butylhydroxybutylnitrosamine; Carrier Proteins; Chemokine CXCL12; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Female; Humans; Immunoenzyme Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Neoplasm Staging; Prognosis; Receptors, CXCR4; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Survival Rate; Thioredoxins; Urinary Bladder Neoplasms | 2011 |
Identification of gene expression signature modulated by nicotinamide in a mouse bladder cancer model.
Topics: Animals; Butylhydroxybutylnitrosamine; Disease Models, Animal; Female; Gene Expression Profiling; Genes, myc; Humans; Mice; Niacinamide; Reproducibility of Results; Species Specificity; Urinary Bladder Neoplasms | 2011 |
Tissue-specific mutagenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine as the basis for urothelial carcinogenesis.
Topics: Animals; Animals, Genetically Modified; Butylhydroxybutylnitrosamine; Carcinogens; Environmental Pollutants; Female; Male; Mice; Mice, Inbred C57BL; Mutagens; Organ Specificity; Rats; Urinary Bladder Neoplasms; Urothelium | 2012 |
In vivo and in vitro effects of RAD001 on bladder cancer.
Topics: Animals; Antineoplastic Agents; Apoptosis; Butylhydroxybutylnitrosamine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Everolimus; Flow Cytometry; G1 Phase; Humans; Immunoblotting; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Proto-Oncogene Proteins c-akt; Resting Phase, Cell Cycle; Sirolimus; TOR Serine-Threonine Kinases; Urinary Bladder Neoplasms | 2013 |
Inorganic arsenic in drinking water accelerates N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tissue damage in mice.
Topics: Animals; Antioxidants; Arsenites; Blotting, Western; Body Weight; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Cytosine; Deoxyguanosine; DNA Damage; DNA Methylation; Drug Synergism; Female; Mice; Mice, Inbred C57BL; Sp1 Transcription Factor; Urinary Bladder; Urinary Bladder Neoplasms; Water Pollutants, Chemical | 2012 |
Chemoprevention with green propolis green propolis extracted in L-lysine versus carcinogenesis promotion with L-lysine in N-Butyl-N-[4-hydroxybutyl] nitrosamine (BBN) induced rat bladder cancer.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Female; Lysine; Plant Extracts; Propolis; Rats; Rats, Wistar; Time Factors; Treatment Outcome; Urinary Bladder Neoplasms | 2012 |
Stat3 activation in urothelial stem cells leads to direct progression to invasive bladder cancer.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Disease Progression; Humans; Mice; Mice, Transgenic; STAT3 Transcription Factor; Stem Cells; Urinary Bladder Neoplasms; Urothelium | 2012 |
Angiogenesis inhibition by green propolis and the angiogenic effect of L-lysine on bladder cancer in rats.
Topics: Angiogenesis Inhibitors; Animals; Butylhydroxybutylnitrosamine; Carcinoma; Disease Models, Animal; Female; Lysine; Neovascularization, Pathologic; Plant Extracts; Propolis; Rats; Rats, Wistar; Time Factors; Treatment Outcome; Urinary Bladder Neoplasms; Water | 2012 |
Long-term treatment with L-isoleucine or L-leucine in AIN-93G diet has promoting effects on rat bladder carcinogenesis.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Diet; Dietary Supplements; Hydrogen-Ion Concentration; Isoleucine; Leucine; Male; Papilloma; Rats; Rats, Inbred F344; Urinalysis; Urinary Bladder; Urinary Bladder Neoplasms; Urothelium | 2012 |
Chemopreventive efficacy of Atorvastatin against nitrosamine-induced rat bladder cancer: antioxidant, anti-proliferative and anti-inflammatory properties.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Antioxidants; Atorvastatin; Biomarkers, Tumor; Butylhydroxybutylnitrosamine; Cell Proliferation; Drug Evaluation, Preclinical; Heptanoic Acids; Male; Oxidative Stress; Pyrroles; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms | 2012 |
Inhibition of bladder tumor growth by chitooligosaccharides in an experimental carcinogenesis model.
Topics: Animals; Anti-Inflammatory Agents; Anticarcinogenic Agents; Beverages; Butylhydroxybutylnitrosamine; Cell Proliferation; Citrus sinensis; Dose-Response Relationship, Drug; Male; Neoplasms, Experimental; Oligosaccharides; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 2012 |
Influence of pertussis toxin on superficial bladder carcinoma in rats.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Female; Pertussis Toxin; Rats; Rats, Wistar; Urinary Bladder Neoplasms; Urine | 2002 |
Simultaneous treatment with benzyl isothiocyanate, a strong bladder promoter, inhibits rat urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitrosamine; Isothiocyanates; Male; Organ Size; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 2002 |
[Use of Azopiram for rapid diagnosis of epithelial tumors of the urinary bladder (experimental data)].
Topics: Aminopyrine; Aniline Compounds; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Hematuria; Male; Rats; Urinary Bladder Neoplasms | 2002 |
Inhibitory effect of clotrimazole on angiogenesis associated with bladder epithelium proliferation in rats.
Topics: Animals; Base Sequence; Butylhydroxybutylnitrosamine; Cell Division; Clotrimazole; Disease Models, Animal; Endothelial Growth Factors; Epithelium; Female; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Lymphokines; Molecular Sequence Data; Neovascularization, Pathologic; Probability; Random Allocation; Rats; Rats, Wistar; Reference Values; Reverse Transcriptase Polymerase Chain Reaction; Sensitivity and Specificity; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factors | 2003 |
Preventive effects of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rat by green tea leaves.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Camellia sinensis; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Phytotherapy; Plant Leaves; Plant Preparations; Rats; Rats, Wistar; Tea; Treatment Outcome; Urinary Bladder Neoplasms | 2003 |
Inhibitory effects of 2-mercaptoethane sulfonate and 6-phenylhexyl isothiocyanate on urinary bladder tumorigenesis in rats induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Isothiocyanates; Male; Mesna; Models, Chemical; Protective Agents; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms | 2003 |
Enhancement of urinary bladder carcinogenesis by combined treatment with benzyl isothiocyanate and N-butyl-N-(4-hydroxybutyl)nitrosamine in rats after initiation.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Drug Combinations; Hyperplasia; Isothiocyanates; Male; Organ Size; Rats; Rats, Inbred F344; Risk Factors; Urinary Bladder Neoplasms | 2003 |
Significance of overexpression of metallothionein in mouse urinary bladder focal lesions induced by treatment with N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Immunohistochemistry; Male; Metallothionein; Mice; Mice, Inbred C57BL; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Urinary Bladder; Urinary Bladder Neoplasms | 2003 |
Accelerated induction of bladder cancer in patched heterozygous mutant mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cell Division; Cocarcinogenesis; Gene Deletion; Genotype; Heterozygote; In Situ Nick-End Labeling; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Neoplasm Invasiveness; Patched Receptors; Patched-1 Receptor; Receptors, Cell Surface; Urinary Bladder; Urinary Bladder Neoplasms | 2004 |
Nrf2 is essential for the chemopreventive efficacy of oltipraz against urinary bladder carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; DNA-Binding Proteins; Enzyme Induction; Female; Gene Expression; Genetic Predisposition to Disease; Glucuronides; Glucuronosyltransferase; Inactivation, Metabolic; Male; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Knockout; Microsomes, Liver; NF-E2-Related Factor 2; Pyrazines; Thiones; Thiophenes; Trans-Activators; Urinary Bladder; Urinary Bladder Neoplasms | 2004 |
Gene expression in the bladder carcinoma rat model.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Disease Models, Animal; DNA, Complementary; Gene Expression; Gene Expression Profiling; Insulin-Like Growth Factor II; Male; Rats; Rats, Wistar; RNA, Long Noncoding; RNA, Untranslated; Time Factors; Up-Regulation; Urinary Bladder Neoplasms | 2004 |
Inactivation of the FHIT gene favors bladder cancer development.
Topics: Acid Anhydride Hydrolases; Adenoviridae; Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Line; Cell Line, Tumor; Female; Flow Cytometry; Genetic Therapy; Genotype; Heterozygote; Humans; Immunoblotting; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Proteins; Time Factors; Urinary Bladder Neoplasms | 2004 |
4-Hydroxybutyl(butyl)nitrosamine-induced urinary bladder cancers in mice: characterization of FHIT and survivin expression and chemopreventive effects of indomethacin.
Topics: Acid Anhydride Hydrolases; Animals; Anti-Inflammatory Agents, Non-Steroidal; Butylhydroxybutylnitrosamine; Carcinogens; Immunohistochemistry; Indomethacin; Inhibitor of Apoptosis Proteins; Male; Mice; Microtubule-Associated Proteins; Neoplasm Proteins; Repressor Proteins; Survivin; Urinary Bladder Neoplasms | 2005 |
Absence of FGFR3 mutations in urinary bladder tumours of rats and mice treated with N-butyl-N-(-4-hydroxybutyl)nitrosamine.
Topics: Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinoma; DNA, Neoplasm; Humans; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Mutagenesis; Mutagens; Mutation; Polymorphism, Single-Stranded Conformational; Protein Isoforms; Protein-Tyrosine Kinases; Rats; Rats, Inbred F344; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; Sequence Analysis, DNA; Urinary Bladder Neoplasms | 2005 |
A survivin gene signature predicts aggressive tumor behavior.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Disease Progression; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Inhibitor of Apoptosis Proteins; Membrane Proteins; Mice; Mice, Transgenic; Microtubule-Associated Proteins; Neoplasm Proteins; Polymerase Chain Reaction; Survivin; Transgenes; Tumor Suppressor Protein p53; Urinary Bladder; Urinary Bladder Neoplasms; Uroplakin II | 2005 |
Tumour-suppression activity of the proapoptotic regulator Par4.
Topics: Age Factors; Animals; Apoptosis; Butylhydroxybutylnitrosamine; Endometrial Neoplasms; Estradiol; Female; Histological Techniques; Immunoblotting; Male; Mice; Mice, Mutant Strains; Phenotype; Prostatic Neoplasms; Proteins; Receptors, Thrombin; Testosterone; Urinary Bladder Neoplasms; X-Linked Inhibitor of Apoptosis Protein | 2005 |
Suppressive effect of 1,4-phenylene diisothiocyanate on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Cyclin D1; Immunohistochemistry; Male; Mice; Mice, Inbred ICR; Thiocyanates; Urinary Bladder Neoplasms | 2005 |
Differences in susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis between SD/gShi rats with spontaneous hypospermatogenesis and SD/cShi rats with spontaneous hydronephrosis.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Enzyme Inhibitors; Hydronephrosis; Male; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Spermatogenesis; Urinary Bladder Neoplasms | 2005 |
Chemoprevention of mouse urinary bladder carcinogenesis by fermented brown rice and rice bran.
Topics: Analysis of Variance; Animals; Butylhydroxybutylnitrosamine; Cell Proliferation; Diet; Hyperplasia; Male; Mice; Mice, Inbred ICR; Nucleolus Organizer Region; Oryza; Precancerous Conditions; Silver Staining; Urinary Bladder; Urinary Bladder Neoplasms | 2006 |
Chemopreventive effects of cyclooxygenase-2 inhibitor and epidermal growth factor-receptor kinase inhibitor on rat urinary bladder carcinogenesis.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cyclooxygenase Inhibitors; Gefitinib; Male; Meloxicam; Protein Kinase Inhibitors; Quinazolines; Rats; Rats, Inbred F344; Thiazines; Thiazoles; Treatment Outcome; Urinary Bladder Neoplasms | 2006 |
Evaluation of DNA content in preneoplastic changes of mouse urinary bladder induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; DNA; Female; Image Processing, Computer-Assisted; Mice; Precancerous Conditions; Urinary Bladder Neoplasms | 2005 |
Cytokeratin-20 and seminal vesicle secretory protein VI as possible marker proteins in urinary bladder preneoplastic lesions induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Animals; Biomarkers; Butylhydroxybutylnitrosamine; Keratin-20; Keratins; Male; Precancerous Conditions; Proteomics; Rats; Rats, Sprague-Dawley; Seminal Vesicle Secretory Proteins; Urinary Bladder Neoplasms | 2006 |
Chemically induced bladder cancer--a sonographic and morphologic description.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Disease Models, Animal; Female; Rats; Rats, Wistar; Ultrasonography; Urinary Bladder; Urinary Bladder Neoplasms | 2006 |
[Development of invasive urinary bladder carcinomas].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Chernobyl Nuclear Accident; Female; Male; Mice; Mice, Knockout; Mutation; Neoplasms, Radiation-Induced; Rats; Tumor Suppressor Protein p53; Ukraine; Urinary Bladder; Urinary Bladder Neoplasms | 2006 |
Effects of ginger (Zingiber officinale Roscoe) on DNA damage and development of urothelial tumors in a mouse bladder carcinogenesis model.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Disease Models, Animal; DNA Damage; Male; Methylnitrosourea; Mice; Neoplasm Invasiveness; Plant Extracts; Urinary Bladder Neoplasms; Urologic Neoplasms; Zingiber officinale | 2006 |
Chemopreventive property of dietary ginger in rat urinary bladder chemical carcinogenesis.
Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Cell Proliferation; Cell Transformation, Neoplastic; Chemoprevention; Dietary Supplements; Dose-Response Relationship, Drug; Male; Plant Extracts; Rats; Rats, Wistar; Uracil; Urinary Bladder Neoplasms; Zingiber officinale | 2006 |
E-cadherin expression during urothelial carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Cadherins; Carcinoma, Papillary; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Female; Hyperplasia; Neoplasm Invasiveness; Papilloma; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urothelium | 2006 |
Dietary beta-cryptoxanthin inhibits N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Cryptoxanthins; Cyclin D1; Male; Mice; Mice, Inbred ICR; Urinary Bladder Neoplasms; Xanthophylls | 2007 |
DNA study of bladder papillary tumours chemically induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in Fisher rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Papillary; Chromosome Aberrations; Cytogenetics; DNA, Neoplasm; Female; Neoplasms, Experimental; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urothelium | 2007 |
Gene expression profiling of chemically induced rat bladder tumors.
Topics: Animals; Annexin A1; Apoptosis; Butylhydroxybutylnitrosamine; Cell Cycle; ErbB Receptors; Gene Expression Profiling; Immunohistochemistry; Mice; Oligonucleotide Array Sequence Analysis; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; Urinary Bladder Neoplasms | 2007 |
Nrf2 and p53 cooperatively protect against BBN-induced urinary bladder carcinogenesis.
Topics: Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinogens; DNA Primers; Genetic Predisposition to Disease; Mice; Mice, Inbred C57BL; Mice, Inbred ICR; Mice, Transgenic; Mutation; NF-E2-Related Factor 2; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms | 2007 |
Null mutation for macrophage migration inhibitory factor (MIF) is associated with less aggressive bladder cancer in mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Disease Progression; Gene Expression; Immunohistochemistry; Intramolecular Oxidoreductases; Macrophage Migration-Inhibitory Factors; Male; Mice; Mice, Knockout; Mutation; Neoplasm Invasiveness; Neoplasm Staging; RNA, Messenger; Urinary Bladder Neoplasms | 2007 |
Tissue levels of pyrimidine nucleoside phosphorylase activity in human and rodent bladder cancer and normal bladder tissue.
Topics: Adult; Aged; Aged, 80 and over; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Papillary; Female; Humans; Male; Mice; Mice, Inbred C3H; Middle Aged; Neoplasm Invasiveness; Neoplasm Recurrence, Local; Pentosyltransferases; Pyrimidine Phosphorylases; Rats; Rats, Inbred F344; Risk Factors; Species Specificity; Thymidine Phosphorylase; Urinary Bladder; Urinary Bladder Neoplasms | 2007 |
A phyllodes tumor of the urinary bladder in a rat.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Carcinogens; Cell Transformation, Neoplastic; Coloring Agents; DNA, Neoplasm; Eosine Yellowish-(YS); Female; Hematoxylin; Phyllodes Tumor; Rats; Rats, Inbred F344; Rosaniline Dyes; Urinary Bladder Neoplasms | 2007 |
Susceptibility of p27 kip1 knockout mice to urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine may not simply be due to enhanced proliferation.
Topics: Animals; Base Sequence; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p27; DNA Primers; Female; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Organ Size; Urinary Bladder Neoplasms | 2008 |
Chemopreventive effects of silymarin and silibinin on N-butyl-N-(4-hydroxybutyl) nitrosamine induced urinary bladder carcinogenesis in male ICR mice.
Topics: Animals; Anticarcinogenic Agents; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Cell Proliferation; Cyclin D1; Male; Mice; Mice, Inbred ICR; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphorylation; Silybin; Silymarin; Urinary Bladder Neoplasms | 2007 |
Fez1/Lzts1-deficient mice are more susceptible to N-butyl-N-(4-hydroxybutil) nitrosamine (BBN) carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; DNA Primers; DNA-Binding Proteins; Female; Genes, Tumor Suppressor; Genetic Predisposition to Disease; Male; Mice; Mice, Knockout; Nerve Tissue Proteins; Urinary Bladder Neoplasms | 2008 |
Inhibition of urinary bladder carcinogenesis by broccoli sprouts.
Topics: Animal Feed; Animals; Anticarcinogenic Agents; Brassica; Butylhydroxybutylnitrosamine; Female; Gene Expression Regulation; Glutathione Transferase; Isothiocyanates; Models, Biological; Quinone Reductases; Rats; Rats, Sprague-Dawley; Time Factors; Urinary Bladder Neoplasms | 2008 |
Effect of cranberry juice concentrate on chemically-induced urinary bladder cancers.
Topics: Animals; Butylhydroxybutylnitrosamine; Chromatography, Liquid; Female; Phytotherapy; Plant Extracts; Rats; Rats, Inbred F344; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Urinary Bladder Neoplasms; Vaccinium macrocarpon | 2008 |
Mixed lymphocyte-autologous tumor cell reaction with primary rat bladder tumors: difficulty in the discrimination of tumor-specific antigen.
Topics: Animals; Antigens, Neoplasm; Butylhydroxybutylnitrosamine; Epitopes; Lymphocyte Culture Test, Mixed; Male; Neoplasms, Experimental; Papilloma; Precancerous Conditions; Rats; Rats, Inbred ACI; Urinary Bladder Neoplasms | 1982 |
Morphologic changes in rat urothelial cells during carcinogenesis: II. Image cytometry.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Nucleus; Chromatin; Cytological Techniques; Male; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder Neoplasms | 1984 |
The use of correspondence analysis in the assessment of morphologic changes during carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Cytological Techniques; Male; Neoplasms; Rats; Rats, Inbred F344; Statistics as Topic; Urinary Bladder Neoplasms | 1984 |
Effects of intravesical instillation of antitumor drugs on the induction of preneoplastic bladder lesions in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Doxorubicin; Female; Hyperplasia; Mitomycin; Mitomycins; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1983 |
Therapeutic effect of a retinoid (Ro 10-9359) on rats with bladder tumours induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine upon administration alone or in combination with mitomycin C.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Butylhydroxybutylnitrosamine; Drug Administration Schedule; Etretinate; Female; Mitomycin; Mitomycins; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1983 |
Delay of bladder cancer induction in rats treated with N-nitroso-N-butyl-N-(4-hydroxybutyl)amine by administration of sodium-2-mercaptoethanesulfonate (Mesna).
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Drinking; Lung Neoplasms; Male; Mercaptoethanol; Mesna; Nitrosamines; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder Neoplasms | 1984 |
Effects of intravesical instillation of antitumor chemotherapeutic agents on bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Doxorubicin; Drug Synergism; Female; Hyperplasia; Mitomycin; Mitomycins; Nitrosamines; Papilloma; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1984 |
[Enhancement of urinary bladder carcinogenesis by the rat urine fractionated by molecular weight].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Chemical Fractionation; Male; Molecular Weight; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urine | 1984 |
Morphologic changes in rat urothelial cells during carcinogenesis: I. Histologic and cytologic changes.
Topics: Animals; Butylhydroxybutylnitrosamine; Flow Cytometry; Male; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder Neoplasms; Urine | 1984 |
Effects of three sweeteners on rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Aspartame; Butylhydroxybutylnitrosamine; Diterpenes; Diterpenes, Kaurane; Glucosides; Hyperplasia; Male; Rats; Rats, Inbred F344; Saccharin; Sweetening Agents; Terpenes; Urinary Bladder; Urinary Bladder Neoplasms | 1984 |
[A study on the glucolytic enzyme activities in the experimental vesical cancer induced by N-butyl-N-butanol (4) nitrosamine in rats].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Glucosephosphate Dehydrogenase; Glycolysis; Male; Nitrosamines; Phosphogluconate Dehydrogenase; Rats; Urinary Bladder Neoplasms | 1984 |
Summation and synergism in the promotion of urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)-nitrosamine in F344 rats.
Topics: Allopurinol; Animals; Ascorbic Acid; Butylated Hydroxyanisole; Butylhydroxybutylnitrosamine; Drug Synergism; Hyperplasia; Male; Nitrosamines; Rats; Rats, Inbred F344; Saccharin; Tryptophan; Urinary Bladder; Urinary Bladder Neoplasms | 1984 |
Drugs, food additives and natural products as promoters in rat urinary bladder carcinogenesis.
Topics: Animals; Ascorbic Acid; Biphenyl Compounds; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Butylhydroxybutylnitrosamine; Carcinogens; Food Additives; Hyperplasia; Male; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1984 |
Inhibition of tumor development in the regenerating rat urinary bladder stimulated to proliferate by cyclophosphamide.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Division; Cyclophosphamide; Dose-Response Relationship, Drug; Female; Mucous Membrane; Papilloma; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1984 |
Principal components analysis of haematological data from F344 rats with bladder cancer fed N-(ethyl)-all-trans-retinamide.
Topics: Analysis of Variance; Animals; Antineoplastic Agents; Blood; Blood Cell Count; Blood Cells; Butylhydroxybutylnitrosamine; Drug Evaluation, Preclinical; Erythrocytes; Female; Hemoglobins; Rats; Rats, Inbred F344; Time Factors; Tretinoin; Urinary Bladder Neoplasms | 1984 |
Comparative carcinogenicity of N-butyl-N-(3-carboxypropyl)-nitrosamine and N-butyl-N-(4-hydroxybutyl)nitrosamine for the urinary bladder of (C57BL/6 X DBA/2)F1 mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Female; Male; Mice; Mice, Inbred Strains; Nitrosamines; Sex Factors; Structure-Activity Relationship; Urinary Bladder Neoplasms | 1984 |
Effect of splenectomy on the growth of carcinogen-induced experimental bladder cancer in mice and rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Male; Mice; Mice, Inbred Strains; Nitrosamines; Rats; Rats, Inbred F344; Splenectomy; Urinary Bladder Neoplasms | 1984 |
[Study on the thymic lymphocytes in the rats treated with bladder cancer-inducing BBN--in vitro effect of the thymus humoral factor].
Topics: Animals; Butylhydroxybutylnitrosamine; Cattle; Concanavalin A; In Vitro Techniques; Lymphocyte Activation; Rats; Rats, Inbred Strains; Thymus Hormones; Urinary Bladder Neoplasms | 1983 |
Single-cell origin of bladder cancer induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in mice with cellular mosaicism.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Electrophoresis; Mice; Mosaicism; Nitrosamines; Phosphoglycerate Kinase; Urinary Bladder Neoplasms | 1983 |
Inhibitory effect of partial cystectomy on experimental carcinogenesis in the urinary bladder.
Topics: Animals; Biotransformation; Butylhydroxybutylnitrosamine; Cell Division; Cyclophosphamide; DNA; Female; Kidney; Liver; Rats; Rats, Inbred Strains; Regeneration; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
Effect of quercetin on two-stage carcinogenesis of the rat urinary bladder.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Diet; Flavonoids; Hyperplasia; Male; Nitrosamines; Papilloma; Quercetin; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1983 |
Promoting effect of sodium o-phenylphenate and o-phenylphenol on two-stage urinary bladder carcinogenesis in rats.
Topics: Animals; Biphenyl Compounds; Body Weight; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Male; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1983 |
[Histological study of urinary bladder tumor: DNA of rat urinary bladder tumor caused by N-butyl-N-(4-hydroxybutyl) nitrosamine and that of human bladder tumor].
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Transformation, Neoplastic; Disease Models, Animal; DNA, Neoplasm; Humans; Male; Nitrosamines; Papilloma; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1983 |
[Effect of reduced glutathione on N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancer in rats].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Glutathione; Humans; Male; Nitrosamines; Papilloma; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1983 |
Cataracts in rats given a bladder carcinogen, N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Cataract; Epithelium; Female; Lens, Crystalline; Nitrosamines; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1983 |
L-Isoleucine and L-leucine are promoters of bladder cancer in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cells, Cultured; Isoleucine; Leucine; Male; Rats; Urinary Bladder Neoplasms | 1983 |
Promoting effects of various chemicals in rat urinary bladder carcinogenesis initiated by N-nitroso-n-butyl-(4-hydroxybutyl)amine.
Topics: Acetazolamide; Allopurinol; Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Quercetin; Rats; Rats, Inbred F344; Saccharin; Tryptophan; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
Inhibition of experimental urinary bladder carcinogenesis by partial cystectomy.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Division; Endothelium; Female; Rats; Rats, Inbred Strains; Regeneration; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
Possible mechanistic roles of anatomical and functional vascular changes in rat urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Analysis of Variance; Animals; Butylhydroxybutylnitrosamine; Male; Nitrosamines; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1984 |
Promotion by ascorbic acid, sodium erythorbate and ethoxyquin of neoplastic lesions in rats initiated with N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Electrolytes; Ethoxyquin; Hydrogen-Ion Concentration; Hyperplasia; Male; Nitrosamines; Organ Size; Osmolar Concentration; Papilloma; Quinolines; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1984 |
Promoting effects of unilateral ureteric ligation on two-stage urinary bladder carcinogenesis in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Hyperplasia; Kidney; Ligation; Liver; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Ureter; Urinary Bladder Neoplasms | 1984 |
Rapid induction of carcinoma in situ in dog urinary bladder by sequential treatment with N-methyl-N'-nitrosourea and N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma in Situ; Dogs; Drug Administration Schedule; Female; Methylnitrosourea; Nitrosamines; Nitrosourea Compounds; Time Factors; Urinary Bladder Neoplasms | 1984 |
Dose-response study of urinary bladder carcinogenesis in rats by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Dose-Response Relationship, Drug; Male; Nitrosamines; Rats; Rats, Inbred F344; Species Specificity; Urinary Bladder Neoplasms | 1984 |
[Effect of cis-diamminedichloroplatinum (II) (CDDP) on bladder cancer on rats induced by N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)].
Topics: Animals; Butylhydroxybutylnitrosamine; Cisplatin; Cyclophosphamide; Female; Mitomycin; Mitomycins; Neoplasms, Experimental; Nitrosamines; Organ Size; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1982 |
[Effect of FT-207 on bladder cancer in rats induced by BBN. II: The effect of oral administration of FT-207 during oncogenesis of bladder cancer].
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Butylhydroxybutylnitrosamine; Fluorouracil; Male; Neoplasms, Experimental; Organ Size; Rats; Rats, Inbred Strains; Tegafur; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
Modifying factors in urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cell Transformation, Neoplastic; Neoplasms, Experimental; Nitrosamines; Rats; Saccharin; Tryptophan; Urinary Bladder Neoplasms | 1983 |
Species variations in the metabolism of N-butyl-N-(4-hydroxybutyl) nitrosamine and related compounds in relation to urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cricetinae; Dogs; Guinea Pigs; Male; Mesocricetus; Mice; Mice, Inbred ICR; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred Strains; Species Specificity; Urinary Bladder Neoplasms | 1983 |
Agglutination assay of bladder cells by Concanavalin A proved the high susceptibility of analbuminemic rats to bladder carcinogens.
Topics: 2-Naphthylamine; Agglutination Tests; Aminobiphenyl Compounds; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cells, Cultured; Concanavalin A; Diet; Disease Susceptibility; Drug Evaluation, Preclinical; FANFT; Male; Rats; Rats, Inbred Strains; Saccharin; Serum Albumin; Urinary Bladder; Urinary Bladder Neoplasms | 1983 |
Effects of promoters on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in the rat.
Topics: 2-Acetylaminofluorene; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Dose-Response Relationship, Drug; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Membrane Potentials; Neoplasms, Experimental; Nitrosamines; Phenobarbital; Precancerous Conditions; Rats; Saccharin; Urinary Bladder Neoplasms | 1983 |
Relationship of urinary N-butyl-N-(3-carboxypropyl)nitrosamine to susceptibility of animals to bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cricetinae; Guinea Pigs; Male; Mesocricetus; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred Strains; Species Specificity; Urinary Bladder Neoplasms | 1983 |
Dose response of saccharin in induction of urinary bladder hyperplasias in Fischer 344 rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Dose-Response Relationship, Drug; Female; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms | 1980 |
Emergence of an epidermis-associated cell surface antigen in epithelial cells of the rat urinary bladder in carcinogenesis.
Topics: Animals; Antigens, Surface; Butylhydroxybutylnitrosamine; Cell Membrane; Cells, Cultured; Epidermis; Epithelium; Hemadsorption; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1981 |
Organ-specific promoting effects of phenobarbital sodium and sodium saccharin in the induction of liver and urinary bladder tumors in male F344 rats.
Topics: 2-Acetylaminofluorene; Animals; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Hyperplasia; Liver Neoplasms, Experimental; Male; Neoplasms, Experimental; Organ Specificity; Phenobarbital; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
Effects of rat urine fractionated by molecular weight on urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Male; Molecular Weight; Neoplasms, Experimental; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urine | 1982 |
High susceptibility of analbuminaemic rats to induced bladder cancer.
Topics: Animals; Butylhydroxybutylnitrosamine; Disease Susceptibility; Male; Neoplasms, Experimental; Rats; Serum Albumin; Urinary Bladder Neoplasms | 1982 |
Histopathological analysis of preneoplastic changes during N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; Epithelium; Hyperplasia; Kinetics; Male; Nitrosamines; Papilloma; Precancerous Conditions; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1982 |
Intravesical single and combination therapy in superficial bladder cancer. An experimental study.
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Doxorubicin; Drug Therapy, Combination; Female; Mitomycins; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
Effect of partial cystectomy on the induction of pre-neoplastic lesions in rat bladder initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine followed by bladder carcinogens and promoters.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cyclamates; FANFT; Male; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Saccharin; Tryptophan; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
Induction of preneoplastic and neoplastic lesions in rats treated N-nitroso compounds.
Topics: Animals; Butylhydroxybutylnitrosamine; Diethylnitrosamine; Dimethylnitrosamine; Dose-Response Relationship, Drug; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1982 |
Influence of 15 retinoic acid amides on urinary bladder carcinogenesis in the mouse.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Diet; Mice; Molecular Conformation; Neoplasms, Experimental; Tretinoin; Urinary Bladder Neoplasms | 1982 |
Cytochemical studies of LDH isoenzymes in experimental bladder tumors.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Isoenzymes; L-Lactate Dehydrogenase; Male; Neoplasms, Experimental; Papilloma; Rats; Rats, Inbred ACI; Time Factors; Urinary Bladder Neoplasms | 1982 |
Enhancing effect of diethylstilbestrol on urinary bladder carcinogenesis in neonatally castrated male rats.
Topics: Animals; Animals, Newborn; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Castration; Cocarcinogenesis; Diethylstilbestrol; Hyperplasia; Male; Neoplasms, Experimental; Papilloma; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
Detection of amino acids as possible promoters of bladder cancer in rats by measuring their enhancement of agglutination of bladder cells by concanavalin A.
Topics: Amino Acids; Animals; Butylhydroxybutylnitrosamine; Cell Aggregation; Cocarcinogenesis; Concanavalin A; Male; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1982 |
[Effect of carboquone (esquinone) on the development of urinary bladder tumors in rats induced by N-butyl-N-(4-hydroxybutyl) nitrosamine].
Topics: Animals; Azirines; Butylhydroxybutylnitrosamine; Carbazilquinone; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1982 |
Urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in dogs.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; Cystoscopy; Dogs; Female; Hematuria; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Papilloma; Urinary Bladder Neoplasms | 1981 |
The cellular features of developing carcinoma in murine urinary bladder.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Neoplasms, Experimental; Nitrosamines; Rats; Urinary Bladder Neoplasms | 1981 |
Effect of cyclophosphamide on rat urinary bladder epithelium treated wtih N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Cyclophosphamide; Epithelium; Hyperplasia; Male; Nitrosamines; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1980 |
Influence of total dose and dose schedule on induction of urinary bladder cancer in the mouse by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Dose-Response Relationship, Drug; Drug Administration Schedule; Male; Mice; Neoplasms, Experimental; Nitrosamines; Urinary Bladder Neoplasms | 1981 |
Metabolic fate of N-butyl-N-(4-hydroxybutyl)nitrosamine in the rat.
Topics: Animals; Biotransformation; Butylhydroxybutylnitrosamine; Chromatography, Thin Layer; Hydrolysis; Male; Methylation; Neoplasms, Experimental; Nitrosamines; Rats; Urinary Bladder Neoplasms | 1980 |
Metabolic fate of N-butyl-N-(4-hydroxybutyl)nitrosamine homologs in the rat, in relation to their organotropic carcinogenicity to the urinary bladder.
Topics: Animals; Butylhydroxybutylnitrosamine; Chromatography, Thin Layer; Male; Nitrosamines; Rats; Urinary Bladder Neoplasms | 1981 |
Metabolic fate of N-alkyl-N-(3-hydroxypropyl and 2-hydroxy-ethyl)nitrosamines in the rat in relation to the induction of bladder cancer by N-butyl-N-(4-hydroxybutyl)nitrosamine and its homologs.
Topics: Animals; Butylhydroxybutylnitrosamine; Chromatography, Thin Layer; Diethylnitrosamine; Male; Nitrosamines; Rats; Urinary Bladder Neoplasms | 1981 |
Inhibitory effect of 4,4'-diaminodiphenylmethane on liver, kidney and bladder carcinogenesis in rats ingesting N-ethyl-N-hydroxyethylnitrosamine or N-butyl-N-(4-hydroxybutyl) nitros-amine.
Topics: Aniline Compounds; Animals; Benzhydryl Compounds; Butylhydroxybutylnitrosamine; Carcinogens; Diethylnitrosamine; Kidney Neoplasms; Liver Neoplasms; Male; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1981 |
Maintenance by saccharin of membrane alterations of rat bladder cells induced by subcarcinogenic treatment with bladder carcinogens.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Aggregation; Cell Membrane; Cocarcinogenesis; Concanavalin A; Diet; FANFT; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Rats, Inbred Strains; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms | 1981 |
Metabolic fate and carcinogenicity of N-(omega-hydroxyalkyl) N-(4-hydroxybutyl) nitrosamines analogs of N-butyl-N-(4-hydroxy-butyl) nitrosamine, in the rat.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Chemical Phenomena; Chemistry; Chromatography, Thin Layer; Male; Nitrosamines; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1981 |
Metabolic fate of N-butyl-N-(4-hydroxybutyl) nitrosamine and N, N-dibutylnitrosamine in the guinea pig, with reference to their carcinogenic effects on the urinary bladder.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Chromatography, Thin Layer; Guinea Pigs; Male; Neoplasms, Experimental; Nitrosamines; Species Specificity; Urinary Bladder Neoplasms | 1981 |
Bladder carcinogenesis in mice induced by N-butyl-N-(4-hydroxybutyl) nitrosamine and N-ethyl-N-(4-hydroxybutyl)-nitrosamine with reference to the effect of cyclophosphamide.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cyclophosphamide; Male; Mice; Mice, Inbred BALB C; Neoplasms, Experimental; Nitrosamines; Urinary Bladder Neoplasms | 1981 |
Effect of simultaneous administration of leupeptin on induction of bladder tumors in rats by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Leupeptins; Male; Neoplasms, Experimental; Nitrosamines; Oligopeptides; Rats; Urinary Bladder Neoplasms | 1980 |
[Experimental carcinogenesis in the urinary bladder against a background of Freund adjuvant and levamisole administration].
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Cell Transformation, Neoplastic; Freund's Adjuvant; Levamisole; Male; Neoplasms, Experimental; Nitrosamines; Papilloma; Rats; Time Factors; Urinary Bladder Neoplasms | 1980 |
Inhibitory effect of an aromatic retinoic acid analog on urinary bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Cricetinae; Etretinate; Hyperplasia; Male; Mice; Nitrosamines; Papilloma; Precancerous Conditions; Rats; Tretinoin; Urinary Bladder; Urinary Bladder Neoplasms | 1980 |
Effects of sodium saccharin and caffeine on the urinary bladder of rats treated with n-butyl-n-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Caffeine; Cocarcinogenesis; Male; Microscopy, Electron; Neoplasms, Experimental; Rats; Saccharin; Urinary Bladder Neoplasms | 1980 |
Lack of enhancing effect of mucosal regeneration following ulceration of the urinary bladder on N-butyl-N-(4-hydroxybutyl)nitrosamine carcinogenesis in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Cell Division; Male; Mucous Membrane; Nitrosamines; Rats; Regeneration; Time Factors; Ulcer; Urinary Bladder; Urinary Bladder Diseases; Urinary Bladder Neoplasms | 1980 |
Enhancement by urine of urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Male; Neoplasms, Experimental; Rats; Urinary Bladder Neoplasms; Urine | 1981 |
Effect of Schistosoma haematobium and N-butyl-N-(4-hydroxybutyl)nitrosamine on the development of urothelial neoplasia in the baboon.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Hematocrit; Male; Neoplasms, Experimental; Nitrosamines; Papio; Schistosoma haematobium; Schistosomiasis; Ureter; Urinary Bladder; Urinary Bladder Neoplasms | 1980 |
N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in C57BL/6 X DBA/2 F1 mice as a useful model for study of chemoprevention of cancer with retinoids.
Topics: Animals; Butylhydroxybutylnitrosamine; Disease Models, Animal; Male; Mice; Microscopy, Electron; Neoplasms, Experimental; Nitrosamines; Tretinoin; Urinary Bladder Neoplasms | 1981 |
Inhibition of urinary bladder cancer by N-(ethyl)-all-trans-retinamide and N-(2-hydroxyethyl)-all-trans-retinamide in rats and mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Female; Male; Mice; Neoplasms, Experimental; Nitrosamines; Rats; Tretinoin; Urinary Bladder Neoplasms | 1981 |
Chemoprevention of urinary bladder carcinogenesis by the natural phenolic compound protocatechuic acid in rats.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Cell Nucleus; Chemoprevention; Dose-Response Relationship, Drug; Hydroxybenzoates; Male; Papilloma; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1995 |
Frequent mutations of the p53 gene and infrequent H- and K-ras mutations in urinary bladder carcinomas of NON/Shi mice treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Amino Acid Sequence; Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; DNA Primers; DNA, Neoplasm; Exons; Genes, p53; Genes, ras; Humans; Male; Mice; Mice, Inbred Strains; Molecular Sequence Data; Mutagenesis; Neoplasm Invasiveness; Point Mutation; Polymerase Chain Reaction; Polymorphism, Genetic; Urinary Bladder Neoplasms | 1995 |
Lack of promoting effects of alpha-linolenic, linoleic or palmitic acid on urinary bladder carcinogenesis in rats.
Topics: alpha-Linolenic Acid; Animals; Butylated Hydroxyanisole; Butylhydroxybutylnitrosamine; Hyperplasia; Kidney; Linoleic Acid; Linoleic Acids; Male; Organ Size; Palmitic Acid; Palmitic Acids; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1995 |
Basement membrane and carcinogenesis: ultrastructural observations in the basement membrane of the bladder epithelium in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN).
Topics: Animals; Basement Membrane; Butylhydroxybutylnitrosamine; Cell Division; Desmosomes; Epithelium; Male; Microscopy, Electron; Microvilli; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 1994 |
Differences in cell proliferation and apoptosis between reversible and irreversible mucosal lesions associated with uracil-induced urolithiasis in N-butyl-N-(4-hydroxybutyl)nitrosamine-pretreated.
Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Cell Division; Male; Microscopy, Electron; Mucous Membrane; Papilloma; Precancerous Conditions; Rats; Rats, Inbred F344; Uracil; Urinary Bladder; Urinary Bladder Neoplasms; Urinary Calculi | 1995 |
Photodynamic diagnosis following topical application of delta-aminolevulinic acid in a rat bladder tumor model.
Topics: Administration, Intravesical; Aminolevulinic Acid; Animals; Butylhydroxybutylnitrosamine; Carcinoma; Carcinoma, Papillary; Cystoscopy; Female; Fluorometry; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 1994 |
Subcellular localization and characterization of interleukin-1 alpha produced by rat bladder cancer cells.
Topics: Animals; Butylhydroxybutylnitrosamine; Interleukin-1; Molecular Weight; Rats; Rats, Inbred ACI; Subcellular Fractions; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Urinary Bladder Neoplasms | 1994 |
Basement membrane and tumor invasion: ultrastructural observations in the basement membrane of rat bladder with invasive transitional cell carcinoma induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Basement Membrane; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Male; Microscopy, Electron; Neoplasm Invasiveness; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 1994 |
Inhibiting effects of diethylmaleate or NH4Cl on NaHCO3, but not butylated hydroxyanisole, promotion of urinary bladder carcinogenesis in male F344 rats initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Ammonium Chloride; Animals; Butylated Hydroxyanisole; Butylhydroxybutylnitrosamine; Lipid Peroxidation; Male; Maleates; Papilloma; Rats; Rats, Inbred F344; Sodium Bicarbonate; Urinary Bladder Neoplasms | 1994 |
Increased gap junctional intercellular communication capacity and connexin 43 and 26 expression in rat bladder carcinogenesis.
Topics: Aminobiphenyl Compounds; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cell Communication; Cell Line; Connexin 26; Connexin 43; Connexins; Epithelial Cells; Gap Junctions; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Rats; Rats, Inbred ACI; Rats, Inbred F344; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms | 1994 |
Detection of O6-butyl- and O6-(4-hydroxybutyl)guanine in urothelial and hepatic DNA of rats given the bladder carcinogen N-nitrosobutyl(4-hydroxybutyl)amine.
Topics: Acyclovir; Animals; Antibodies; Antibody Specificity; Butylhydroxybutylnitrosamine; DNA; DNA Damage; Enzyme-Linked Immunosorbent Assay; Guanine; Liver; Male; Mass Spectrometry; Rabbits; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1994 |
p53 mutations in early neoplastic lesions of the urinary bladder in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Base Sequence; Butylhydroxybutylnitrosamine; Exons; Genes, p53; Male; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1994 |
Effect of phenacetin pretreatment on renal pelvic carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine in NON/Shi mice of both sexes.
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Hydronephrosis; Hyperplasia; Kidney Neoplasms; Kidney Pelvis; Male; Mice; Phenacetin; Sex Factors; Urinary Bladder Neoplasms | 1994 |
DNA methylation adduct formation and H-ras gene mutations in progression of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tumors caused by a single exposure to N-methyl-N-nitrosourea.
Topics: Administration, Oral; Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Deoxyguanosine; Disease Progression; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA, Neoplasm; Genes, ras; Injections, Intraperitoneal; Male; Methylation; Methylnitrosourea; Molecular Sequence Data; Neoplasm Invasiveness; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1994 |
Modification of N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated urinary bladder carcinogenesis in rats by phytic acid and its salts.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Hydrogen-Ion Concentration; Male; Papilloma; Phytic Acid; Potassium; Rats; Rats, Inbred F344; Sodium; Urinary Bladder Neoplasms | 1994 |
[Effect of intravesical bacillus Calmette-Guérin on N-butyl-N-(4-hydroxybutyl)-nitrosamine induced urinary bladder carcinogenesis in rats].
Topics: Administration, Intravesical; Animals; BCG Vaccine; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Female; Papilloma; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1994 |
Lack of promotion of N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated urinary bladder carcinogenesis in mice by rat cancer promoters.
Topics: Animals; Ascorbic Acid; Biphenyl Compounds; Butylated Hydroxyanisole; Butylhydroxybutylnitrosamine; Carcinogens; Male; Mice; Rats; Urinary Bladder Neoplasms | 1993 |
Influences of aging and sex on renal pelvic carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine in NON/Shi mice.
Topics: Aging; Animals; Body Weight; Butylhydroxybutylnitrosamine; Female; Kidney Neoplasms; Kidney Pelvis; Male; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Sex Factors; Urinary Bladder Neoplasms | 1994 |
[Influence of Lactobacillus casei on rat bladder carcinogenesis].
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Transformation, Neoplastic; Lacticaseibacillus casei; Male; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 1994 |
Severity of promotion by sodium salts of succinic acid in rat urinary bladder carcinogenesis correlates with sodium ion concentration under conditions of equal urinary pH.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Epithelium; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred F344; Sodium; Succinates; Succinic Acid; Urinary Bladder; Urinary Bladder Neoplasms | 1993 |
Chemoprevention of mouse urinary bladder carcinogenesis by the naturally occurring carotenoid astaxanthin.
Topics: Animals; Anticarcinogenic Agents; beta Carotene; Body Weight; Butylhydroxybutylnitrosamine; Canthaxanthin; Carotenoids; Liver; Male; Mice; Mice, Inbred ICR; Nucleolus Organizer Region; Organ Size; Precancerous Conditions; Silver Staining; Urinary Bladder Neoplasms; Xanthophylls | 1994 |
[Inhibitory effect of antitumor-B and retinamide on precancerous lesions of the bladder in rats].
Topics: Animals; Antineoplastic Agents, Phytogenic; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Drugs, Chinese Herbal; Precancerous Conditions; Rats; Rats, Wistar; Tretinoin; Urinary Bladder Neoplasms | 1993 |
Chemoprevention of OH-BBN-induced bladder cancer in mice by piroxicam.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Drug Synergism; Eflornithine; Fenretinide; Male; Mice; Piroxicam; Urinary Bladder Neoplasms | 1993 |
Expression patterns of loricrin in various species and tissues.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Differentiation; Cricetinae; Female; Humans; Male; Membrane Proteins; Mesocricetus; Metaplasia; Mice; Mice, Inbred Strains; Organ Specificity; Rabbits; Rats; Rats, Inbred F344; Species Specificity; Trachea; Urinary Bladder Neoplasms; Vagina; Vitamin A Deficiency | 1993 |
[Early changes of sugar chains in bladder luminal cell membrane of rat treated with N-butyl-N-(4-hydroxybutyl) nitrosamine detected by immunohistochemical transmission electron microscopy].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Membrane; Epithelium; Glycoproteins; Immunohistochemistry; Lectins; Male; Microscopy, Electron; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms | 1993 |
Acetylsalicylic acid inhibition of n-butyl-(4-hydroxybutyl)nitrosamine-induced bladder carcinogenesis in rats.
Topics: Animals; Anticarcinogenic Agents; Aspirin; Butylhydroxybutylnitrosamine; Male; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 1993 |
[Effects of androgen regulation system on bladder carcinogenesis in male mice].
Topics: 5-alpha Reductase Inhibitors; Androgen Antagonists; Animals; Butylhydroxybutylnitrosamine; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Leuprolide; Male; Mice; Mice, Inbred C3H; Orchiectomy; Urinary Bladder Neoplasms | 1995 |
Immunohistochemically demonstrated variation in expression of cathepsin E between uracil-induced papillomatosis and N-butyl-N-(4-hydroxybutyl)nitrosamine-induced preneoplastic and neoplastic changes in rat urinary bladder.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cathepsin E; Cathepsins; Immunohistochemistry; Male; Neoplasm Proteins; Neoplasms, Experimental; Papilloma; Rats; Rats, Inbred F344; Uracil; Urinary Bladder; Urinary Bladder Neoplasms | 1996 |
p53 mutations in transitional cell carcinomas of the urinary bladder in rats treated with N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; DNA Primers; DNA, Neoplasm; Genes, p53; Male; Molecular Sequence Data; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1996 |
Differential activity of aspirin, ketoprofen and sulindac as cancer chemopreventive agents in the mouse urinary bladder.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; Aspirin; Butylhydroxybutylnitrosamine; Carcinogens; Diet; Humans; Ketoprofen; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Sulindac; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1996 |
Morphological changes of microvilli on different surfaces of epithelial cells in the rat bladder treated with N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Epithelium; Male; Microscopy, Electron; Microvilli; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms | 1995 |
A study of antitumor effects of thymosin on rat and mouse urinary bladder carcinoma induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Female; Killer Cells, Natural; Mice; Mice, Inbred C3H; Organ Size; Rats; Rats, Wistar; Thymosin; Urinary Bladder Neoplasms | 1996 |
Absence of promoting potential of bracken fern (Pteridium aquilinum) in rat urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine and uracil.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Male; Papilloma; Plants, Toxic; Rats; Rats, Wistar; Uracil; Urinary Bladder Neoplasms | 1995 |
Interstitial stroma and carcinogenesis: ultrastructural observations in the rat bladder treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Epithelium; Male; Microscopy, Electron; Microscopy, Electron, Scanning; Neovascularization, Pathologic; Rats; Rats, Wistar; Sodium Hydroxide; Stromal Cells; Urinary Bladder Neoplasms | 1996 |
Localization of zinc and metallothionein in the rat bladder epithelium during carcinogenesis induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Epithelium; Histocytochemistry; Hyperplasia; Immunohistochemistry; Male; Metallothionein; Neoplasm Invasiveness; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms; Zinc | 1996 |
Enhanced gene expression of transforming growth factor-alpha and c-met in rat urinary bladder cancer.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Cell Movement; Gene Expression; Growth Substances; Hepatocyte Growth Factor; Male; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-met; Rats; Rats, Sprague-Dawley; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; RNA, Messenger; Transforming Growth Factor alpha; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1996 |
Promoting effects of dimethylarsinic acid on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in rats.
Topics: Animals; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Cacodylic Acid; Carcinogens; Cell Division; Cocarcinogenesis; Dose-Response Relationship, Drug; Epithelium; Male; Microscopy, Electron, Scanning; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1996 |
Promoting effect of unilateral nephrectomy on urinary bladder carcinogenesis in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Drinking; Male; Nephrectomy; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1996 |
Morphological changes in the basement membrane during progression from non-invasive to invasive rat bladder cancer induced by N-butyl-N-(4-hydoxybutyl) nitrosamine.
Topics: Animals; Basement Membrane; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Male; Microscopy, Electron; Neoplasm Invasiveness; Neoplasm Staging; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 1997 |
Promoting effects and mechanisms of action of androgen in bladder carcinogenesis in male rats.
Topics: Administration, Oral; Androgen Antagonists; Animals; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Cholestenone 5 alpha-Reductase; Disease Models, Animal; Enzyme Inhibitors; Finasteride; Flutamide; Gonadotropin-Releasing Hormone; Immunohistochemistry; Leuprolide; Male; Mice; Mice, Inbred C3H; Oxidoreductases; Rats; Rats, Wistar; Urinary Bladder Neoplasms | 1997 |
Effects of Lentinus edodes, Grifola frondosa and Pleurotus ostreatus administration on cancer outbreak, and activities of macrophages and lymphocytes in mice treated with a carcinogen, N-butyl-N-butanolnitrosoamine.
Topics: Animals; Antibiotics, Antineoplastic; Basidiomycota; beta-Glucans; Butylhydroxybutylnitrosamine; Carcinogens; Cells, Cultured; Chemotaxis; Concanavalin A; Cytotoxicity, Immunologic; Disease Outbreaks; Eating; Female; Glucans; Lentinan; Lymphocyte Activation; Lymphocytes; Macrophages; Medicine, Traditional; Mice; Mice, Inbred ICR; Neoplasms; Polyporaceae; Polysaccharides; Spleen; Urinary Bladder Neoplasms | 1997 |
Strain differences in sensitivity to the promoting effect of sodium L-ascorbate in a two-stage rat urinary bladder carcinogenesis model.
Topics: Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Male; Organ Size; Rats; Rats, Inbred Lew; Rats, Inbred Strains; Species Specificity; Survival Rate; Urinary Bladder; Urinary Bladder Neoplasms; Water Supply | 1997 |
Lack of involvement of p53 gene mutations in N-methyl-N-nitrosourea-induced bladder tumor progression in N-butyl-N-(4-hydroxybutyl)nitrosamine-treated rats and no suppression by indomethacin.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cocarcinogenesis; Disease Progression; Genes, p53; Indomethacin; Male; Methylnitrosourea; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1997 |
Endoscopic observation for detection and monitoring of N-butyl-N-(4-hydroxybutyl)nitrosamine--induced bladder tumor in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Endoscopy; Female; Mucous Membrane; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1997 |
p53 gene mutation in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder tumors and N-methyl-N-nitrosourea-induced colon tumors of rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Colonic Neoplasms; Exons; Genes, p53; Male; Methylnitrosourea; Point Mutation; Polymorphism, Single-Stranded Conformational; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1997 |
Chemopreventive efficacy of piroxicam administered alone or in combination with lycopene and beta-carotene on the development of rat urinary bladder carcinoma after N-butyl-N-(4-hydroxybutyl)nitrosamine treatment.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticarcinogenic Agents; beta Carotene; Butylhydroxybutylnitrosamine; Carcinogens; Carotenoids; Drug Interactions; Lycopene; Male; Piroxicam; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1997 |
[Changes in tissue and blood polyamines during N-butyl-N-(4-hydroxybutyl) nitrosamine-induced bladder carcinogenesis in rats].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Male; Polyamines; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1997 |
Quantitative trait loci associated with promoting effects of sodium L-ascorbate on two-stage bladder carcinogenesis in rats.
Topics: Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Disease Susceptibility; Drug Synergism; Male; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1997 |
Lack of promotion of urinary bladder carcinogenesis by sodium bicarbonate and/or L-ascorbic acid in male ODS/Shi-od/od rats synthesizing alpha 2 mu-globulin but not L-ascorbic acid.
Topics: alpha-Macroglobulins; Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Cocarcinogenesis; Drug Combinations; Eating; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred F344; Rats, Mutant Strains; Sodium; Sodium Bicarbonate; Urinalysis; Urinary Bladder Neoplasms | 1997 |
Cyclin D1 overexpression in rat two-stage bladder carcinogenesis and its relationship with oncogenes, tumor suppressor genes, and cell proliferation.
Topics: Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cell Nucleus; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Hyperplasia; Male; Neoplasm Proteins; Papilloma; Precancerous Conditions; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; RNA, Messenger; Tumor Suppressor Protein p53; Urinary Bladder; Urinary Bladder Neoplasms | 1997 |
Genetic instability and p53 mutations in metastatic foci of mouse urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; DNA, Complementary; DNA, Neoplasm; Genes, p53; Male; Mice; Point Mutation; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Urinary Bladder Neoplasms | 1997 |
A histopathological mapping study of the urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in dogs.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Papillary; Disease Progression; Dogs; Dose-Response Relationship, Drug; Female; Neoplasm Invasiveness; Urinary Bladder Neoplasms | 1997 |
Chemopreventive effects of diosmin and hesperidin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary-bladder carcinogenesis in male ICR mice.
Topics: Administration, Oral; Animals; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Carcinogens; Diosmin; DNA, Neoplasm; Drug Combinations; Hesperidin; Male; Mice; Mice, Inbred ICR; Nucleolus Organizer Region; Precancerous Conditions; Silver Staining; Urinary Bladder Diseases; Urinary Bladder Neoplasms | 1997 |
[Changes in tissue and blood polyamine levels following chemotherapy in rats with urinary bladder carcinoma induced by N-butyl-N-(4-hydroxybutyl) nitosamine in rats].
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Diamines; Male; Polyamines; Rats; Rats, Inbred F344; Spermidine; Spermine; Urinary Bladder Neoplasms | 1997 |
Infrequent involvement of microsatellite instability in urinary bladder carcinomas of the NON/Shi mouse treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; DNA Replication; Male; Mice; Microsatellite Repeats; Neoplasm Metastasis; Urinary Bladder Neoplasms | 1998 |
Frequent p53 mutations and occasional loss of chromosome 4 in invasive bladder carcinoma induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in B6D2F1 mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Chromosome Deletion; Humans; Male; Mice; Mutation; Tumor Suppressor Protein p53; Uracil; Urinary Bladder Neoplasms | 1998 |
Inhibitory effect of tomato juice on rat urinary bladder carcinogenesis after N-butyl-N-(4-hydroxybutyl)nitrosamine initiation.
Topics: Animals; Anticarcinogenic Agents; Antioxidants; Butylhydroxybutylnitrosamine; Carotenoids; Liver; Lycopene; Male; Organ Size; Rats; Rats, Inbred F344; Solanum lycopersicum; Urinary Bladder Neoplasms | 1998 |
F344/Shi rats bearing type b catalase-1 locus are sensitive to sodium L-ascorbate promotion of two-stage urinary bladder carcinogenesis.
Topics: Alleles; Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Catalase; Disease Susceptibility; Hyperplasia; Male; Neoplasms, Squamous Cell; Papilloma; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1998 |
Apoptosis and carcinogenesis: morphologic observations in the rat bladder treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Coloring Agents; Eosine Yellowish-(YS); Fluorescent Dyes; Genetic Techniques; Hematoxylin; Male; Microscopy, Electron; Neoplasm Invasiveness; Rats; Rats, Wistar; Staining and Labeling; Urinary Bladder Neoplasms | 1998 |
Clonal analysis of urothelial carcinomas in C3H/HeN<-->BALB/c chimeric mice treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Chimera; Genes, p53; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Mutagenesis; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Urinary Bladder Neoplasms | 1998 |
Chemopreventive effects of nimesulide, a selective cyclooxygenase-2 inhibitor, on the development of rat urinary bladder carcinomas initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Cyclooxygenase Inhibitors; Eating; Incidence; Male; Organ Size; Rats; Rats, Inbred F344; Sulfonamides; Urinary Bladder Neoplasms | 1998 |
Strong promoting activity of phenylethyl isothiocyanate and benzyl isothiocyanate on urinary bladder carcinogenesis in F344 male rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Diet; Diethylnitrosamine; Drug Synergism; Hyperplasia; Isothiocyanates; Liver; Male; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1998 |
Possible rare involvement of O6-methylguanine formation as a significant mutational factor in mouse urinary bladder carcinogenesis models.
Topics: Adenosine Deaminase; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Epithelium; Female; Genes, p53; Guanine; Humans; Incidence; Male; Mice; Mice, Inbred C3H; Mice, Transgenic; Mutation; Neoplasm Invasiveness; O(6)-Methylguanine-DNA Methyltransferase; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Urinary Bladder; Urinary Bladder Neoplasms | 1998 |
High susceptibility of p53(+/-) knockout mice in N-butyl-N-(4-hydroxybutyl)nitrosamine urinary bladder carcinogenesis and lack of frequent mutation in residual allele.
Topics: Alleles; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Disease Susceptibility; Genes, p53; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Mutation; Urinary Bladder Neoplasms | 1998 |
Histological evaluation of the effects of electropermeabilization after administration of bleomycin on bladder cancer in the rat.
Topics: Animals; Antibiotics, Antineoplastic; Bleomycin; Butylhydroxybutylnitrosamine; Combined Modality Therapy; Electrodes, Implanted; Electromagnetic Fields; Male; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms | 1998 |
Changes in the activities of mitochondrial enzymes in the progress of tumorigenesis of bladder cancer.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; Disease Progression; Electron Transport Complex IV; Male; Mitochondria; NADH Dehydrogenase; Rats; Rats, Sprague-Dawley; Succinate Cytochrome c Oxidoreductase; Urinary Bladder; Urinary Bladder Neoplasms | 1998 |
[A model of rat's urinary bladder tumor induced by subcutaneous injection of N-butyl-N-(4-hydroxybutyl)-nitrosamine].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma in Situ; Carcinoma, Transitional Cell; Disease Models, Animal; Glucuronidase; Papilloma; Rats; Urinary Bladder Neoplasms | 1998 |
Host genes affecting survival period of chemically induced bladder cancer in mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Chromosome Mapping; Genetic Linkage; Genetic Predisposition to Disease; Male; Mice; Mice, Inbred Strains; Microsatellite Repeats; Quantitative Trait, Heritable; Survival Analysis; Urinary Bladder Neoplasms | 1998 |
The dynamics of the imprinted H19 gene expression in the mouse model of bladder carcinoma induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cell Transformation, Neoplastic; Disease Models, Animal; Disease Progression; Epithelial Cells; Female; Gene Expression; Genomic Imprinting; In Situ Hybridization; Mice; Mice, Inbred C3H; Muscle Proteins; Precancerous Conditions; RNA, Long Noncoding; RNA, Untranslated; Urinary Bladder Neoplasms | 1998 |
A comparative analysis of allelic imbalance events in chemically induced rat mammary, colon, and bladder tumors.
Topics: Alleles; Animals; Azoxymethane; Butylhydroxybutylnitrosamine; Carcinogens; Chromosome Mapping; Codon; Colonic Neoplasms; Female; Genes, ras; Genetic Markers; Humans; Loss of Heterozygosity; Male; Mammary Neoplasms, Experimental; Methylnitrosourea; Microsatellite Repeats; Point Mutation; Rats; Rats, Inbred F344; Rats, Inbred WF; Urinary Bladder Neoplasms | 1999 |
Promotion by sodium L-ascorbate in rat two-stage urinary bladder carcinogenesis is dependent on the interval of administration.
Topics: Animals; Ascorbic Acid; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Drug Administration Schedule; Hyperplasia; Male; Papilloma; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1999 |
Enhancement of urinary bladder carcinogenesis in nullizygous p53-deficient mice by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Carcinogens; Carcinoma in Situ; Carcinoma, Transitional Cell; Cocarcinogenesis; Gene Deletion; Genes, p53; Genotype; Male; Mice; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Urinary Bladder Neoplasms | 1999 |
Expression of vascular endothelial growth factor in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat bladder carcinogenesis.
Topics: Animals; Antibodies, Monoclonal; Blotting, Northern; Butylhydroxybutylnitrosamine; Carcinogens; Endothelial Growth Factors; Fibroblast Growth Factor 2; Gene Expression Regulation; Immunohistochemistry; Lymphokines; Male; Microscopy, Electron; Neovascularization, Pathologic; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors; von Willebrand Factor | 1999 |
LOH and mutational analysis of p53 alleles in mouse urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Alleles; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Crosses, Genetic; DNA Mutational Analysis; DNA, Neoplasm; Genes, p53; Loss of Heterozygosity; Male; Mice; Mice, Inbred C3H; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Sequence Analysis, DNA; Urinary Bladder Neoplasms | 1999 |
Inhibition of urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine in rats by green tea.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Catechin; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperplasia; Male; Papilloma; Rats; Rats, Wistar; Tea; Urinary Bladder Neoplasms | 1999 |
Antitumour effects of the angiogenesis inhibitor AGM-1470 on rat urinary bladder tumours induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Animals; Antibiotics, Antineoplastic; Butylhydroxybutylnitrosamine; Carcinogens; Cyclohexanes; Female; Neovascularization, Pathologic; O-(Chloroacetylcarbamoyl)fumagillol; Rats; Rats, Inbred F344; Sesquiterpenes; Urinary Bladder Neoplasms | 1999 |
Promotion of NCI-Black-Reiter male rat bladder carcinogenesis by dimethylarsinic acid an organic arsenic compound.
Topics: Alpha-Globulins; Animals; Butylhydroxybutylnitrosamine; Cacodylic Acid; Carcinogenicity Tests; DNA, Neoplasm; Herbicides; Hyperplasia; Immunohistochemistry; Kidney; Male; Precancerous Conditions; Rats; Rats, Inbred F344; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1998 |
Elevation of urinary enzyme levels in rat bladder carcinogenesis.
Topics: Acetylglucosaminidase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Butylhydroxybutylnitrosamine; Female; Isoenzymes; L-Lactate Dehydrogenase; Male; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder Neoplasms | 1999 |
Promoting effects of intravesical instillation of saline on bladder lesion development in rats pretreated with N-butyl-N-(4-hydroxybutyl) nitrosamine are inhibited by bacillus Calmette-Guerin.
Topics: Animals; BCG Vaccine; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Growth; Immunohistochemistry; Incidence; Papilloma; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; Sodium Chloride; Time Factors; Urinary Bladder Neoplasms | 1999 |
Effects of uracil calculi on cell growth and apoptosis in the BBN-initiated Wistar rat urinary bladder mucosa.
Topics: Animals; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Cell Division; Hyperplasia; Male; Mucous Membrane; Papilloma; Proliferating Cell Nuclear Antigen; Rats; Rats, Wistar; Uracil; Urinary Bladder; Urinary Bladder Calculi; Urinary Bladder Neoplasms | 1999 |
Metallothionein modulates the carcinogenicity of N-butyl-N-(4-hydroxybutyl)nitrosamine in mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Carcinogens; Carcinoma, Transitional Cell; Chlorides; Metallothionein; Mice; Mice, Transgenic; Urinary Bladder Neoplasms; Zinc Compounds | 1999 |
Reduced expression of the CDK inhibitor p27(KIP1) in rat two-stage bladder carcinogenesis and its association with expression profiles of p21(WAF1/Cip1) and p53.
Topics: Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Cycle Proteins; Cell Division; Cocarcinogenesis; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Disease Progression; Gene Expression Regulation, Neoplastic; Genes, p53; Hyperplasia; Male; Microtubule-Associated Proteins; Neoplasm Proteins; Papilloma; Rats; Rats, Inbred F344; RNA, Messenger; RNA, Neoplasm; Tumor Suppressor Protein p53; Tumor Suppressor Proteins; Urinary Bladder Neoplasms; Urothelium | 1999 |
A functional and quantitative mutational analysis of p53 mutations in yeast indicates strand biases and different roles of mutations in DMBA- and BBN-induced tumors in rats.
Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Base Sequence; Butylhydroxybutylnitrosamine; Carcinogens; Color; False Positive Reactions; Female; Genes, p53; Male; Molecular Sequence Data; Mutagenicity Tests; Neoplasms, Experimental; Ovarian Neoplasms; Point Mutation; Rats; Rats, Inbred F344; Sensitivity and Specificity; Urinary Bladder Neoplasms; Yeasts | 1999 |
Effect of fleroxacin on mouse bladder carcinogenesis with N-butyl-N- (4-hydroxybutyl) nitrosamine.
Topics: Animals; Anti-Infective Agents; Butylhydroxybutylnitrosamine; Carcinogens; Female; Fleroxacin; Mice; Mice, Inbred C57BL; Time Factors; Urinary Bladder Neoplasms | 1999 |
Loss of heterozygosity in (LewisxF344)F1 rat urinary bladder tumors induced with N-butyl-N-(4-hydroxybutyl)nitrosamine followed by dimethylarsinic acid or sodium L-ascorbate.
Topics: Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Cacodylic Acid; Carcinogenicity Tests; Carcinoma; Hyperplasia; Loss of Heterozygosity; Male; Microsatellite Repeats; Papilloma; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Rats, Inbred Lew; Urinary Bladder; Urinary Bladder Neoplasms | 1999 |
[Effect of liarozole on the cell proliferation activity in the rat urinary bladder epithelium induced by N-butyl-N-(4-hydroxybutyl) nitrosamine].
Topics: Animals; Antineoplastic Agents, Hormonal; Butylhydroxybutylnitrosamine; Cell Division; Depression, Chemical; Dose-Response Relationship, Drug; Epithelial Cells; Epithelium; Imidazoles; Male; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms | 1999 |
Increased expression of cyclooxygenase-2 protein in rat urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Animals; Blotting, Western; Butylhydroxybutylnitrosamine; Carcinogens; Cyclooxygenase 1; Cyclooxygenase 2; Epithelial Cells; Immunohistochemistry; Isoenzymes; Male; Membrane Proteins; Papilloma; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1999 |
Aberrant expression of p27(Kip1) is associated with malignant transformation of the rat urinary bladder epithelium.
Topics: Animals; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Cell Cycle Proteins; Cyclin D1; Cyclin E; Cyclin-Dependent Kinase Inhibitor p27; Male; Microtubule-Associated Proteins; Papilloma; Rats; Rats, Inbred F344; Tumor Suppressor Proteins; Uracil; Urinary Bladder Calculi; Urinary Bladder Neoplasms | 2000 |
Concentration dependent promoting effects of sodium L-ascorbate with the same total dose in a rat two-stage urinary bladder carcinogenesis.
Topics: Animals; Ascorbic Acid; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Carcinogens; Dose-Response Relationship, Drug; Male; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1999 |
Inhibitory effects of 1,3-diaminopropane, an ornithine decarboxylase inhibitor, on rat two-stage urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Acetyltransferases; Animals; Anticarcinogenic Agents; Apoptosis; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Cocarcinogenesis; Cyclin D1; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinases; Diamines; Endothelial Growth Factors; Hydrogen-Ion Concentration; Hyperplasia; Lymphokines; Male; Ornithine Decarboxylase; Ornithine Decarboxylase Inhibitors; Papilloma; Polyamines; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; RNA, Messenger; Urinary Bladder; Urinary Bladder Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
Long-term administration of galactoside-specific mistletoe lectin in an animal model: no protection against N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis in rats and no induction of a relevant local cellular immune response
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Disease Models, Animal; Drug Administration Schedule; Female; Galactosides; Immunity, Cellular; Immunohistochemistry; Incidence; Lectins; Mistletoe; Phytotherapy; Plant Lectins; Plant Preparations; Plant Proteins; Plants, Medicinal; Rats; Rats, Wistar; Ribosome Inactivating Proteins, Type 2; Specific Pathogen-Free Organisms; Toxins, Biological; Treatment Failure; Urinary Bladder Neoplasms | 2000 |
Low susceptibility of Long-Evans Cinnamon rats to N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder carcinogenesis and inhibitory effect of urinary copper.
Topics: Age Factors; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Chelating Agents; Copper; Copper Sulfate; Disease Susceptibility; Hydrogen-Ion Concentration; Iron; Male; Metallothionein; Penicillamine; Rats; Rats, Inbred F344; Rats, Inbred LEC; Rats, Long-Evans; Species Specificity; Urinary Bladder Neoplasms; Urine; Zinc | 2000 |
Significant overexpression of metallothionein and cyclin D1 and apoptosis in the early process of rat urinary bladder carcinogenesis induced by treatment with N-butyl-N-(4-hydroxybutyl)nitrosamine or sodium L-ascorbate.
Topics: Animals; Apoptosis; Ascorbic Acid; Butylhydroxybutylnitrosamine; Cyclin D1; DNA, Neoplasm; Flow Cytometry; Male; Metallothionein; Microscopy, Electron; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 2000 |
Transgenic rats carrying copies of the human c-Ha-ras proto-oncogene exhibit enhanced susceptibility to N-butyl-N-(4-hydroxybutyl)nitrosamine bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cocarcinogenesis; Female; Genes, ras; Genetic Predisposition to Disease; Horses; Humans; Immunoblotting; Male; Mutation; Papilloma; Pregnancy; Proto-Oncogene Mas; ras Proteins; Rats; Rats, Sprague-Dawley; Transgenes; Urinary Bladder Neoplasms | 2000 |
Chemopreventive effects of bovine lactoferrin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat bladder carcinogenesis.
Topics: Acetyltransferases; Animals; Anticarcinogenic Agents; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Cattle; Chlorides; Drinking; Eating; Hydrogen-Ion Concentration; Lactoferrin; Liver; Male; Mucous Membrane; Organ Size; Ornithine Decarboxylase; Potassium; Rats; Rats, Inbred F344; Sodium; Urinary Bladder; Urinary Bladder Neoplasms | 2000 |
Effects of astragali radix extract on carcinogenesis, cytokine production, and cytotoxicity in mice treated with a carcinogen, N-butyl-N'-butanolnitrosoamine.
Topics: Animals; Anticarcinogenic Agents; Astragalus Plant; Astragalus propinquus; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Cytokines; Cytotoxicity, Immunologic; Drug Screening Assays, Antitumor; Drugs, Chinese Herbal; Female; Interferon-gamma; Interleukin-2; Killer Cells, Natural; Lymphocyte Activation; Lymphocytes; Mice; Mice, Inbred ICR; Spleen; T-Lymphocytes; Urinary Bladder Neoplasms | 1999 |
Celecoxib inhibits N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced urinary bladder cancers in male B6D2F1 mice and female Fischer-344 rats.
Topics: Animals; Anticarcinogenic Agents; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Isoenzymes; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Organ Specificity; Precancerous Conditions; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Rats; Rats, Inbred F344; Sulfonamides; Urinary Bladder Neoplasms | 2000 |
Preferential gene transfer to BBN-induced rat bladder tumor by simple instillation of adenoviral vector.
Topics: Adenoviridae; Animals; Butylhydroxybutylnitrosamine; Female; Gene Transfer Techniques; Genetic Vectors; Glycosaminoglycans; Rats; Rats, Inbred F344; Tissue Distribution; Urinary Bladder; Urinary Bladder Neoplasms | 2001 |
Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats.
Topics: 1,2-Dimethylhydrazine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Dietary Supplements; Dose-Response Relationship, Drug; Fatty Acids; Female; Glutathione Transferase; Hyperplasia; Linoleic Acid; Mammary Neoplasms, Experimental; Neoplasms; Nitrosamines; Organ Size; Phosphorylation; Rats; Rats, Inbred F344; Rats, Sprague-Dawley; Safflower Oil; Time Factors; Urinary Bladder Neoplasms | 2001 |
Suicide gene therapy for chemically induced rat bladder tumor entailing instillation of adenoviral vectors.
Topics: Adenoviridae; Animals; Antiviral Agents; Apoptosis; Butylhydroxybutylnitrosamine; Carcinogens; Female; Ganciclovir; Genetic Therapy; Genetic Vectors; In Situ Nick-End Labeling; Injections, Intraperitoneal; Rats; Rats, Inbred F344; Simplexvirus; Thymidine Kinase; Urinary Bladder Neoplasms; Vacuoles | 2001 |
Possible involvement of O6-methylguanine formation and p53 dysfunction in mouse urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Cacodylic Acid; Carcinogens; Cell Division; Cell Transformation, Neoplastic; DNA Mutational Analysis; Female; Guanine; Humans; Male; Methylnitrosourea; Mice; Mice, Inbred C3H; Mice, Knockout; Mice, Transgenic; Mutation; O(6)-Methylguanine-DNA Methyltransferase; Polymorphism, Single-Stranded Conformational; RNA, Messenger; Tumor Suppressor Protein p53; Urinary Bladder Neoplasms | 2001 |
Alterations of beta- and gamma-catenin in N-butyl-N-(-4-hydroxybutyl)nitrosamine-induced murine bladder cancer.
Topics: Aged; Animals; beta Catenin; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cytoskeletal Proteins; Desmoplakins; DNA Mutational Analysis; Female; gamma Catenin; Humans; Immunohistochemistry; Male; Mice; Middle Aged; Polymorphism, Single-Stranded Conformational; Trans-Activators; Urinary Bladder Neoplasms | 2001 |
Inhibitory effect of peptide vilon on the development of induced rat urinary bladder tumors in rats.
Topics: Adjuvants, Immunologic; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Dipeptides; Male; Rats; Urinary Bladder Neoplasms | 2001 |
p53 and H-ras mutations and microsatellite instability in renal pelvic carcinomas of NON / Shi mice treated with N-butyl-N-(4-hydroxybutyl)-nitrosamine: different genetic alteration from urinary bladder carcinoma.
Topics: Animals; Butylhydroxybutylnitrosamine; DNA Mutational Analysis; Genes, p53; Genes, ras; Kidney Neoplasms; Mice; Microsatellite Repeats; Mutagenesis; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Urinary Bladder Neoplasms | 2001 |
Lack of enhancing effect of two Kampo medicines, Sho-saiko-to (TJ-9) and Sairei-to (TJ-114), on rat urinary bladder carcinogenesis initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Anti-Inflammatory Agents; Butylhydroxybutylnitrosamine; Drugs, Chinese Herbal; Hyperplasia; Male; Papilloma; Rats; Rats, Inbred F344; Steroids; Urinary Bladder; Urinary Bladder Neoplasms | 2002 |
[Effect of vilon and epithalone on induction and growth of induced bladder neoplasms in rats].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Dipeptides; Male; Oligopeptides; Rats; Urinary Bladder Neoplasms | 2001 |
Chemopreventive effects of a flavonoid antioxidant silymarin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice.
Topics: Administration, Oral; Animals; Anticarcinogenic Agents; Antioxidants; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cell Cycle; Cyclin D1; Male; Mice; Mice, Inbred ICR; Papilloma; Precancerous Conditions; Silymarin; Urinary Bladder Neoplasms | 2002 |
[Study on different responses of rats' small intestine mucous membrane and bladder transitional epithelium in the same carcinogenic urine environment].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Female; Intestinal Mucosa; Mucous Membrane; Rats; Rats, Wistar; Urinary Bladder; Urinary Bladder Neoplasms | 2001 |
Promoting the effects of intravesical instillation of saline on bladder lesion development in rats pre-treated with BBN.
Topics: Administration, Intravesical; Animals; Butylhydroxybutylnitrosamine; Female; Rats; Rats, Inbred F344; Sodium Chloride; Urinary Bladder Neoplasms | 2002 |
Effect of protease inhibitors in mice treated with the hepatocarcinogen, hexachlorocyclohexane (alpha-isomer) and the bladder carcinogen, N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Hepatocellular; Hexachlorocyclohexane; Hyperplasia; Leupeptins; Liver; Liver Neoplasms; Mice; Nitrosamines; Pepstatins; Protease Inhibitors; Urinary Bladder Neoplasms | 1978 |
[Fibrinolytic enzyme system in blood of rats with urinary bladder tumor induced by oral administration of N-butyl-N-(4-hydroxybutyl)-nitrosamine (author's transl)].
Topics: Animals; Butylhydroxybutylnitrosamine; Fibrinolysin; Male; Neoplasms, Experimental; Nitrosamines; Plasminogen Activators; Rats; Urinary Bladder Neoplasms | 1975 |
Stages of transformation in the development of N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced transitional cell carcinomas in the urinary bladder of rats.
Topics: Animals; Autoradiography; Butylhydroxybutylnitrosamine; Carcinoma in Situ; Carcinoma, Papillary; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; DNA, Neoplasm; Female; Hyperplasia; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Urinary Bladder Neoplasms | 1976 |
Morphology, classification and histogenesis of N-butyl-N-(4-hydroxybutyl)-nitrosamine-induced carcinomas in the urinary bladder of rats.
Topics: Adenocarcinoma; Animals; Butylhydroxybutylnitrosamine; Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Female; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Urinary Bladder Neoplasms | 1977 |
A cell line derived from BBN (N-butyl-N-[4-hydroxybutyl]-nitrosamine)-induced rat bladder cancer: establishment and scanning electron microscopic cell surface characteristics.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Line; Clone Cells; Microscopy, Electron, Scanning; Microvilli; Neoplasms, Experimental; Rats; Urinary Bladder Neoplasms | 1978 |
Carcinogenicity of N-nitrosamines related to N-butyl-N-(4-hydroxybutyl)nitrosamine and N,N,-dibutylnitrosamine in ACI/N rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Aspartate Aminotransferases; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Hepatocellular; Liver Neoplasms; Male; Nitrosamines; Rats; Rats, Inbred ACI; Urinary Bladder Neoplasms | 1976 |
A quantitative dosing schedule for the induction of transitional cell carcinomas in female F344 rats with the use of N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Female; Neoplasms, Experimental; Nitrosamines; Precancerous Conditions; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1979 |
Mutagenicity of N-butyl-N-(4-hydroxybutyl)nitrosamine, a bladder carcinogen, and related compounds.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Hydroxylation; In Vitro Techniques; Microsomes, Liver; Mutagens; Mutation; Neoplasms, Experimental; Nitrosamines; Rats; Salmonella typhimurium; Urea; Urinary Bladder Neoplasms | 1977 |
Antigen characteristics of nitrosamine-induced urinary bladder cancer in rats.
Topics: Animals; Antigens, Neoplasm; Antigens, Surface; Butylhydroxybutylnitrosamine; Cytotoxicity Tests, Immunologic; Immunity; Immunologic Techniques; Male; Neoplasm Transplantation; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred ACI; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1979 |
Inhibition of N-n-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder cancer in rats by administration of disulfiram in the diet.
Topics: Animals; Biotransformation; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Disulfiram; Male; Neoplasms, Experimental; Nitrosamines; Rats; Urinary Bladder Calculi; Urinary Bladder Neoplasms | 1979 |
Effect of delay in administration of 13-cis-retinoic acid on the inhibition of urinary bladder carcinogenesis in the rat.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Dose-Response Relationship, Drug; Male; Neoplasms, Experimental; Rats; Rats, Inbred F344; Time Factors; Tretinoin; Urinary Bladder Neoplasms; Vitamin A | 1979 |
Expression of skin antigen on cell-surface of rat urinary bladder epithelial cells in carcinogenesis.
Topics: Animals; Antigens, Surface; Butylhydroxybutylnitrosamine; Epithelium; Male; Metaplasia; Neoplasms, Experimental; Rats; Rats, Inbred ACI; Skin; Urinary Bladder; Urinary Bladder Neoplasms | 1979 |
A technique for multiparametric analysis of hemodynamic changes in rat urinary bladder during carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Hemodynamics; Male; Nitrosamines; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1979 |
[Changes in the urinary bladders of rats during experimental carcinogenesis].
Topics: Alkaline Phosphatase; Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Female; Glucuronidase; Hyperplasia; Male; Monoamine Oxidase; Oxidoreductases; Papilloma; Rats; Urinary Bladder Neoplasms | 1979 |
[Effect of BCG and BCG-CWS on experimental urinary bladder tumors in rats (author's transl)].
Topics: Animals; BCG Vaccine; Butylhydroxybutylnitrosamine; Cell Wall; Female; Immunity, Cellular; Lymphocyte Activation; Neoplasms, Experimental; Rats; Urinary Bladder Neoplasms | 1979 |
Damage and repair of DNA in urinary bladder epithelium of rats treated with N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; DNA; DNA Repair; Epithelium; Male; Neoplasms, Experimental; Nitrosamines; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1977 |
Neovascularization in benign and malignant urinary bladder epithelial proliferative lesions of the rat observed in situ by scanning electron microscopy and autoradiography.
Topics: Animals; Autoradiography; Butylhydroxybutylnitrosamine; Cyclophosphamide; Epithelium; Hyperplasia; Male; Microscopy, Electron, Scanning; Neoplasms, Experimental; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1978 |
Effect of phenacetin and caffeine on the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Caffeine; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Papilloma; Phenacetin; Rats; Urinary Bladder Neoplasms | 1978 |
Inhibitory effect of 13-cis-retinoic acid on urinary bladder carcinogenesis induced in C57BL/6 mice by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Male; Mice; Mice, Inbred C57BL; Neoplasms, Experimental; Nitrosamines; Tretinoin; Urinary Bladder Neoplasms; Vitamin A | 1978 |
Concanavalin A agglutination of bladder cells of rats treated with bladder carcinogens; a rapid new test to detect bladder carcinogens.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cell Aggregation; Concanavalin A; Drug Evaluation, Preclinical; Humans; In Vitro Techniques; Male; Neoplasms, Experimental; Precancerous Conditions; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1978 |
Effect of azathiopurine and OK-432 on urinary bladder carcinogenesis in rats.
Topics: Animals; Azathioprine; Biological Products; Butylhydroxybutylnitrosamine; Drug Synergism; Immunosuppressive Agents; Male; Neoplasms, Experimental; Papilloma; Picibanil; Rats; Urinary Bladder Neoplasms | 1978 |
Effect of vitamin A acetate on urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Male; Neoplasms, Experimental; Nitrosamines; Papilloma; Rats; Urinary Bladder; Urinary Bladder Neoplasms; Vitamin A | 1978 |
Effects of sex hormones on oncogenesis in rat urinary bladder by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Drug Interactions; Estradiol; Estriol; Gonadal Steroid Hormones; Male; Microscopy, Electron, Scanning; Neoplasms, Experimental; Nitrosamines; Rats; Testosterone; Urinary Bladder Neoplasms | 1977 |
Vascular changes during rat urinary bladder carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Capillaries; Male; Neoplasms, Experimental; Nitrosamines; Rats; Urinary Bladder Neoplasms | 1977 |
Summation effect of N-butyl-n-(4-hydroxybutyl)nitrosamine, N-(4-(5-nitro-2-furyl)-2-thiazoly)formamide, N-2-fluoroenylacetamide, and 3,3'-dichlorobenzidine on urinary bladder carcinogenesis in rats.
Topics: 2-Acetylaminofluorene; 3,3'-Dichlorobenzidine; Animals; Benzidines; Biliary Tract Diseases; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Cysts; Fluorenes; Formamides; Hepatic Duct, Common; Hyperplasia; Male; Neoplasms, Experimental; Nitrosamines; Papilloma; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1977 |
Early surface changes of the urinary bladder epithelium of different animal species induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Cilia; Cricetinae; Hyperplasia; Male; Mice; Nitrosamines; Papilloma; Rats; Species Specificity; Urinary Bladder; Urinary Bladder Neoplasms | 1977 |
Synergistic effect of urinary bladder carcinogenesis in rats treated with N-butyl-n-(4-hydroxybutyl)nitrosamine, N-(4-(5-nitro-2-furyl)-2-thiazolyl)formamide,N-2-fluorenylacetamide, and 3,3'-dichlorobenzidine.
Topics: 3,3'-Dichlorobenzidine; Animals; Benzidines; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Drug Synergism; Fatty Liver; Formamides; Liver; Male; Neoplasms, Experimental; Nitrosamines; Papilloma; Precancerous Conditions; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1977 |
Further studies on the effect of leupeptin, a protease inhibitor, on induction of bladder tumors in rats by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Drug Interactions; Leupeptins; Male; Neoplasms, Experimental; Nitrosamines; Oligopeptides; Protease Inhibitors; Rats; Urinary Bladder Neoplasms | 1977 |
13-cis-Retinoic acid: inhibition of bladder carcinogenesis induced in rats by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Male; Neoplasms, Experimental; Nitrosamines; Rats; Rats, Inbred F344; Tretinoin; Urinary Bladder Neoplasms; Vitamin A | 1977 |
Different susceptibilities of the urinary bladder epithelium of animal species to three nitroso compounds.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinoma; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cricetinae; Guinea Pigs; Male; Mice; Nitrosamines; Organ Size; Papilloma; Propionates; Rats; Sarcoma; Urinary Bladder Neoplasms | 1976 |
Effects of sex hormones on development of urinary bladder tumours in rats induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Diethylstilbestrol; Female; Gonadal Steroid Hormones; Male; Papilloma; Rats; Testosterone; Urinary Bladder; Urinary Bladder Neoplasms | 1975 |
Effect of leupeptin, a protease inhibitor, on induction of bladder tumors in rats by n-butyl-n-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Leupeptins; Neoplasms, Experimental; Nitrosamines; Oligopeptides; Rats; Urinary Bladder Neoplasms | 1976 |
Early changes caused by N-butyl-N-(4-hydroxybutyl)nitrosamine in the bladder epithelium of different animal species.
Topics: Animals; Butylhydroxybutylnitrosamine; Cricetinae; Guinea Pigs; Hyperplasia; Male; Mice; Microscopy, Electron; Neoplasms, Experimental; Precancerous Conditions; Rats; Species Specificity; Urinary Bladder Neoplasms | 1976 |
[The lithium carbonate promotion of urothelial tumors in rats induced with N-butyl-N-(4-hydroxybutyl)-nitrosamine].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Epithelium; Lithium Carbonate; Male; Rats; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1992 |
Spermidine/spermine N1-acetyltransferase, a new biochemical marker for epithelial proliferation in rat bladder.
Topics: Acetyltransferases; Animals; Biomarkers, Tumor; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Epithelium; G1 Phase; Hyperplasia; Male; Nuclear Proteins; Ornithine Decarboxylase; Papilloma; Polyamines; Proliferating Cell Nuclear Antigen; Rats; Rats, Inbred F344; S Phase; Triazines; Urinary Bladder; Urinary Bladder Neoplasms | 1992 |
The diverse modification of N-butyl-N-(4-hydroxybutyl) nitrosamine induced carcinogenesis in urinary bladder by dibromodulcitol and dianhydrodulcitol.
Topics: Administration, Intravesical; Administration, Oral; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Dianhydrogalactitol; Doxorubicin; Female; Mitolactol; Papilloma; Precancerous Conditions; Rats; Rats, Sprague-Dawley; Urinary Bladder Neoplasms | 1992 |
Inorganic alkalizers and acidifiers under conditions of high urinary Na+ or K+ on cell proliferation and two-stage carcinogenesis in the rat bladder.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Cell Division; Male; Phosphates; Potassium; Potassium Chloride; Rats; Rats, Inbred F344; Sodium; Sodium Chloride; Urinary Bladder; Urinary Bladder Neoplasms | 1992 |
Anti-promoting effect of nordihydroguaiaretic acid on N-butyl-N-(4-hydroxybutyl)nitrosamine and sodium saccharin-induced rat urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Hyperplasia; Male; Masoprocol; Papilloma; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder Neoplasms | 1992 |
Synergism of environmental carcinogens and promoters on bladder cancer development initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine in F344 rats.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; DNA, Neoplasm; Drug Synergism; Environmental Pollutants; Feeding Behavior; Male; Organ Size; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1992 |
[Promotive effects of intravesical instillation of dimethylsulfoxide on bladder carcinogenesis in mice].
Topics: Administration, Intravesical; Animals; Butylhydroxybutylnitrosamine; Dimethyl Sulfoxide; Female; Mice; Urinary Bladder Neoplasms | 1992 |
[Effects of luteinizing hormone-releasing hormone agonist on bladder carcinogenesis in male rats].
Topics: Animals; Butylhydroxybutylnitrosamine; Hypothalamus; Injections, Subcutaneous; Leuprolide; Male; Orchiectomy; Pituitary Gland; Rats; Rats, Wistar; Testis; Testosterone; Urinary Bladder Neoplasms | 1992 |
Absence of ras oncogene activation in rat urinary bladder carcinomas induced by N-methyl-N-nitrosourea or N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Base Sequence; Blotting, Western; Butylhydroxybutylnitrosamine; DNA, Single-Stranded; Gene Expression; Genes, ras; Male; Methylnitrosourea; Molecular Sequence Data; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1992 |
Low susceptibility of nude mice to induction of invasive urinary bladder cancers by N-ethyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Male; Mice; Mice, Nude; Nitrosamines; Urinary Bladder Neoplasms; Urodynamics | 1992 |
Cell line specific abnormalities in expression of PNA, SBA and L-PHA binding sites by carcinogen induced rat urothelial carcinomas.
Topics: Animals; Binding Sites; Butylhydroxybutylnitrosamine; Chromosome Aberrations; Electrophoresis, Polyacrylamide Gel; FANFT; Gene Expression; Genes, myc; Genes, ras; Glycoproteins; Lectins; Male; Mice; Mice, Nude; Mutation; Neoplasm Proteins; Peanut Agglutinin; Phytohemagglutinins; Plant Lectins; Rats; Rats, Inbred F344; Sodium Dodecyl Sulfate; Soybean Proteins; Urinary Bladder Neoplasms | 1992 |
[Inhibitory effect of vitamin E on rats with bladder tumors induced by N-butyl-N-(4-hydroxybutyl) nitrosamine].
Topics: Animals; Butylhydroxybutylnitrosamine; CD4-CD8 Ratio; Male; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Urinary Bladder Neoplasms; Vitamin E; Vitamin E Deficiency | 1992 |
[Inhibitory effects of IFN on N-butyl-N-(hydroxybutyl) nitrosamine induced rats bladder tumors].
Topics: Animals; Butylhydroxybutylnitrosamine; Cytotoxicity, Immunologic; Female; Interferon-alpha; Killer Cells, Natural; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1992 |
[Histological study on intravesical instillation of Bacillus Calmette Guerin (BCG) and adriamycin for BBN-induced bladder tumor in rats].
Topics: Administration, Intravesical; Animals; BCG Vaccine; Butylhydroxybutylnitrosamine; Doxorubicin; Female; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1992 |
Lectins in diagnosis of bladder carcinoma.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Humans; Immunoenzyme Techniques; Lectins; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1992 |
[Inhibition by proton irradiation on the development of invasive bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl) nitrosamine in mice].
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Mice; Neoplasm Invasiveness; Protons; Radiotherapy Dosage; Urinary Bladder Neoplasms | 1991 |
Timing effects of uracil-induced urolithiasis on amplification of second-stage promotion in rat bladder carcinogenesis.
Topics: Animals; Bicarbonates; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Drug Administration Schedule; Male; Rats; Rats, Inbred F344; Sodium; Sodium Bicarbonate; Uracil; Urinary Bladder; Urinary Bladder Neoplasms; Urinary Calculi | 1991 |
Direct DNA sequencing of the rat neu oncogene transmembrane domain reveals no mutation in urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)nitrosamine, N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide or N-methyl-N-nitrosourea.
Topics: Amino Acid Sequence; Animals; Base Sequence; Butylhydroxybutylnitrosamine; DNA, Neoplasm; FANFT; Male; Membranes; Methylnitrosourea; Molecular Sequence Data; Mutation; Oncogenes; Polymerase Chain Reaction; Proto-Oncogene Proteins; Rats; Rats, Inbred F344; Receptor, ErbB-2; Saccharin; Uracil; Urinary Bladder Neoplasms | 1991 |
Comparative promoting activities of phosphate salts on rat two-stage bladder carcinogenesis under conditions of equivalent urinary Na+ or K+ levels.
Topics: Animals; Butylhydroxybutylnitrosamine; Hydrogen-Ion Concentration; Male; Phosphates; Potassium; Rats; Rats, Inbred F344; Sodium; Urinary Bladder; Urinary Bladder Neoplasms | 1991 |
Summation effects of uracil and other promoters on epithelial lesion development in the F344 rat urinary bladder initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Ascorbic Acid; Body Weight; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Butylhydroxybutylnitrosamine; Carcinogens; Epithelium; Ethoxyquin; Male; Mucous Membrane; Organ Size; Papilloma; Precancerous Conditions; Rats; Rats, Inbred F344; Uracil; Urinary Bladder; Urinary Bladder Neoplasms | 1991 |
Renal pelvic carcinoma which shows metastatic potential to distant organs, induced by N-butyl-N-(4-hydroxybutyl)nitrosamine in NON/Shi mice.
Topics: Abdominal Neoplasms; Animals; Body Weight; Butylhydroxybutylnitrosamine; Disease Models, Animal; Hydronephrosis; Kidney Neoplasms; Kidney Pelvis; Lung Neoplasms; Lymphatic Metastasis; Male; Mice; Mice, Inbred Strains; Neoplasm Metastasis; Urinary Bladder Neoplasms | 1991 |
Lack of bladder carcinogenicity of dietary sodium saccharin in analbuminaemic rats, which are highly susceptible to N-nitroso-n-butyl-(4-hydroxybutyl)amine.
Topics: Administration, Oral; Animals; Body Weight; Butylhydroxybutylnitrosamine; Disease Susceptibility; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred Strains; Saccharin; Serum Albumin; Sodium; Species Specificity; Urinary Bladder Neoplasms | 1991 |
Effects of carotenoid administration on bladder cancer prevention.
Topics: Animals; Antioxidants; Butylhydroxybutylnitrosamine; Canthaxanthin; Carcinoma, Transitional Cell; Carotenoids; Male; Mice; Placebos; Urinary Bladder Neoplasms | 1991 |
Inhibitory effect of 2-O-octadecylascorbic acid in agglutination assay with concanavalin A; short-term examination of rat urinary bladder carcinogenesis.
Topics: Agglutination Tests; Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Cell Aggregation; Concanavalin A; Free Radical Scavengers; Male; Rats; Saccharin; Tryptophan; Urinary Bladder Neoplasms | 1991 |
Time- and dose-dependent induction of invasive urinary bladder cancers by N-ethyl-N-(4-hydroxybutyl)nitrosamine in B6C3F1 mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma in Situ; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Dose-Response Relationship, Drug; Epithelium; Male; Mice; Mice, Inbred Strains; Neoplasm Invasiveness; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1991 |
[A study of BBN induced bladder cancer in mice. The time differences in changes of histopathology and nuclear DNA content].
Topics: Animals; Butylhydroxybutylnitrosamine; DNA, Neoplasm; Female; Hyperplasia; Mice; Mice, Inbred C57BL; Paraffin Embedding; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1991 |
Stimulatory effects of growth hormone on rat bladder carcinogenesis.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Growth Hormone; Male; Rats; Rats, Inbred Strains; Recombinant Proteins; Time Factors; Urinary Bladder Neoplasms | 1991 |
No promotion of urinary bladder carcinogenesis by sodium L-ascorbate in male ODS/Shi-od/od rats lacking L-ascorbic acid-synthesizing ability.
Topics: Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Epithelium; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred F344; Rats, Inbred Strains; Sodium; Urinary Bladder Neoplasms | 1991 |
[Inhibitory effect of Chinese herb medicine zhuling on urinary bladder cancer. An experimental and clinical study].
Topics: Adult; Aged; Animals; Antineoplastic Agents, Phytogenic; Butylhydroxybutylnitrosamine; Drugs, Chinese Herbal; Female; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1991 |
[The anticancer effects of high energy shock waves on rat bladder cancer induced by BBN].
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Lithotripsy; Microscopy, Electron; Microscopy, Electron, Scanning; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1991 |
Nucleolar organizer regions in rat urinary bladder tumors induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Hyperplasia; Male; Nitrosamines; Nucleolus Organizer Region; Precancerous Conditions; Rats; Rats, Inbred ACI; Urinary Bladder Neoplasms | 1990 |
Enhancing effect of partial cystectomy on rat urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Cystectomy; Female; Immunohistochemistry; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1991 |
Uracil-induced calculi and carcinogenesis in the urinary bladder of rats treated simultaneously with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Division; Dinoprostone; Drug Synergism; Male; Rats; Rats, Inbred F344; Uracil; Urinary Bladder; Urinary Bladder Calculi; Urinary Bladder Neoplasms | 1991 |
Comparative bladder tumor promoting activity of sodium saccharin, sodium ascorbate, related acids, and calcium salts in rats.
Topics: Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Calcium Carbonate; Diet; Drinking; Drug Synergism; FANFT; Hydrogen-Ion Concentration; Kidney; Male; Rats; Rats, Inbred F344; Saccharin; Urinary Bladder; Urinary Bladder Neoplasms; Urine | 1991 |
[Sodium nitrate as a possible promotor of bladder carcinogenesis in rats].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Male; Nitrates; Rats; Time Factors; Urinary Bladder Neoplasms | 1991 |
Lack of synergism in rat urinary tract carcinogenesis between prior uracil treatment and N-butyl-N-(4-hydroxybutyl)-nitrosamine administration.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Kidney Neoplasms; Kidney Pelvis; Male; Organ Size; Papilloma; Rats; Rats, Inbred F344; Uracil; Urinary Bladder Neoplasms | 1991 |
Promoting effect of the peroxisome proliferator, clofibrate, but not di(2-ethylhexyl)phthalate, on urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Clofibrate; Diethylhexyl Phthalate; DNA, Neoplasm; Liver; Male; Organ Size; Rats; Rats, Inbred F344; Uracil; Urinary Bladder Neoplasms | 1990 |
Restorative effects of thymosin fraction 5 on reduction in responsiveness of rat thymocytes to allogenic lymphocytes during bladder tumor induction.
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Kinetics; Lymphocyte Culture Test, Mixed; Lymphocytes; Rats; Rats, Inbred F344; Rats, Inbred Strains; T-Lymphocyte Subsets; T-Lymphocytes; Thymosin; Urinary Bladder Neoplasms | 1990 |
Involvement of urine in epithelial-stromal interactions in urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Epithelium; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Urine | 1990 |
[The study of BBN induced bladder cancer in mice. Influence of Freund complete adjuvant and associated immunological reactions in mice].
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Freund's Adjuvant; Hypersensitivity, Delayed; Immunity, Cellular; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Urinary Bladder Neoplasms | 1990 |
Anti-tumor effect of intravesical instillation of OK432 against rat bladder tumors induced by N-butyl-N-(4-hydroxybutyl) nitrosamine.
Topics: Administration, Intravesical; Animals; Butylhydroxybutylnitrosamine; Female; Killer Cells, Natural; Picibanil; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1990 |
Effects of alpha-difluromethylornithine on the development of deeply invasive urinary bladder carcinomas in mice.
Topics: Animals; Butylhydroxybutylnitrosamine; Eflornithine; Male; Mice; Mice, Inbred C3H; Neoplasm Invasiveness; Urinary Bladder Neoplasms | 1990 |
The kinetics of cellular proliferation in rat urinary bladder treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Cell Division; Cystectomy; Female; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1990 |
[Fluorescence microscopy of the absorption and disappearance of adriamycin through the bladder epithelium in the rat].
Topics: Animals; Butylhydroxybutylnitrosamine; Doxorubicin; In Vitro Techniques; Male; Microscopy, Fluorescence; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1990 |
Development of N-butyl-N-(hydroxybutyl)-nitrosamine-induced tumors in the partially resected, proliferating rat urinary bladder in dependence upon the time of onset of stimulated DNA synthesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Division; Cystectomy; DNA; Female; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1990 |
Rat urinary bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)-nitrosamine and N-methyl-N-nitrosourea.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Female; Methylnitrosourea; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1990 |
H-ras activation and ras p21 expression in bladder tumors induced in F344/NCr rats by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Blotting, Southern; Butylhydroxybutylnitrosamine; Carcinoma; Codon; DNA; Gene Expression; Genes, ras; Male; Mutation; Oncogene Protein p21(ras); Papilloma; Polymerase Chain Reaction; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1990 |
Activating missense mutations in Ha-ras-1 genes in a malignant subset of bladder lesions induced by N-butyl-N-(4-hydroxybutyl)nitrosamine or N-[4-(5-nitro-2-furanyl)-2-thiazolyl]formamide.
Topics: Animals; Base Sequence; Butylhydroxybutylnitrosamine; Cell Division; Cell Transformation, Neoplastic; Codon; DNA, Neoplasm; FANFT; Molecular Sequence Data; Mutation; Oligonucleotide Probes; Oligonucleotides; Oncogenes; Polymerase Chain Reaction; Proto-Oncogene Proteins p21(ras); Rats; Urinary Bladder Neoplasms | 1990 |
Stimulation of urinary bladder tumorigenesis by carcinogen-exposed stroma.
Topics: Animals; Butylhydroxybutylnitrosamine; Epithelium; Male; Neoplasm Transplantation; Rats; Rats, Inbred F344; Transplantation, Heterotopic; Urinary Bladder; Urinary Bladder Neoplasms | 1990 |
[Effects of forced diuresis on butylbutanolnitrosamine induction of bladder tumors in rats].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; Diuresis; Hyperplasia; Nitrosamines; Papilloma; Rats; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1990 |
Dose response of N-butyl-N-(4-hydroxybutyl)nitrosamine on urinary bladder carcinogenesis in mutant ODS rats lacking L-ascorbic acid synthesizing ability.
Topics: Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinogenicity Tests; Disease Susceptibility; Dose-Response Relationship, Drug; Male; Nitrosamines; Occult Blood; Rats; Rats, Inbred F344; Rats, Mutant Strains; Urinary Bladder Neoplasms | 1990 |
[Ultrastructure of cultured normal bladder transitional epithelial cell and BBN induced rat bladder tumor cell lines].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Epithelium; Male; Rats; Rats, Inbred Strains; Tumor Cells, Cultured; Urinary Bladder; Urinary Bladder Neoplasms | 1990 |
[Infiltration and tissue concentration of intravesically instilled (2"R)-4'-O-tetrahydropyranyladriamycin or adriamycin in rat bladder tumor induced by BBN].
Topics: Administration, Intravesical; Animals; Butylhydroxybutylnitrosamine; Chromatography, High Pressure Liquid; Doxorubicin; Rats; Rats, Inbred ACI; Tissue Distribution; Urinary Bladder; Urinary Bladder Neoplasms | 1990 |
Squamous and transitional elements in rat bladder carcinomas induced by N-butyl-N-4-hydroxybutyl-nitrosamine (BBN). A study of cytokeratin expression.
Topics: Animals; Antibodies, Monoclonal; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Epithelium; Fluorescent Antibody Technique; Histocytochemistry; Keratins; Male; Papilloma; Rats; Rats, Inbred ACI; Urinary Bladder Neoplasms; Vimentin | 1985 |
Gamma glutamyl transpeptidase activity in rat urothelium treated with bladder carcinogens.
Topics: Animals; Animals, Newborn; Butylhydroxybutylnitrosamine; Carcinogens; Female; gamma-Glutamyltransferase; Histocytochemistry; Hyperplasia; Male; Methylnitrosourea; Mucous Membrane; Rats; Staining and Labeling; Time Factors; Urinary Bladder Neoplasms | 1985 |
Analyses of avidin-biotin complexes with lectins of membrane glycoproteins in the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Avidin; Biotin; Butylhydroxybutylnitrosamine; Glycoproteins; Lectins; Male; Membrane Proteins; Nitrosamines; Rats; Rats, Inbred F344; Staining and Labeling; Urinary Bladder Neoplasms | 1987 |
Effects of intravesical instillation of antitumor chemotherapeutic and immunotherapeutic agents on bladder lesion development in rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Administration, Intravesical; Animals; Antineoplastic Combined Chemotherapy Protocols; Biological Products; Bleomycin; Butylhydroxybutylnitrosamine; Cisplatin; Drug Evaluation, Preclinical; Drug Interactions; Epithelium; Female; Nitrosamines; Picibanil; Precancerous Conditions; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Suppression of rat urinary bladder carcinogenesis by alpha-difluoromethylornithine.
Topics: Administration, Oral; Animals; Butylhydroxybutylnitrosamine; Eflornithine; Male; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1989 |
Inhibitory action of alpha-difluoromethylornithine on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Drug Administration Schedule; Eflornithine; Male; Neoplasms, Experimental; Putrescine; Rats; Rats, Inbred F344; Spermidine; Spermine; Time Factors; Urinary Bladder Neoplasms | 1989 |
[Effects of LH-RH analogue on pituitary-testicular axis and bladder carcinogenesis of BBN administered male rats].
Topics: Animals; Butylhydroxybutylnitrosamine; Gonadotropin-Releasing Hormone; Leuprolide; Male; Pituitary Gland; Rats; Rats, Inbred Strains; Testis; Urinary Bladder Neoplasms | 1989 |
Effects of urinary potassium and sodium ion concentrations and pH on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in rats.
Topics: Animals; Bicarbonates; Butylhydroxybutylnitrosamine; Carcinogens; Hydrogen-Ion Concentration; Hyperplasia; Male; Nitrosamines; Papilloma; Potassium; Rats; Rats, Inbred Strains; Sodium; Sodium Bicarbonate; Urinary Bladder; Urinary Bladder Neoplasms | 1989 |
Effects of sodium salts of phenobarbital and barbital on development of bladder tumors in male F344/NCr rats pretreated with either N-[4-(5-nitro-2-furyl)-2-thiazolyl]formamide or N-nitrosobutyl-4-hydroxybutylamine.
Topics: Animals; Barbital; Barbiturates; Butylhydroxybutylnitrosamine; Carcinoma; Cocarcinogenesis; FANFT; Male; Papilloma; Phenobarbital; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1989 |
Bladder cancers. Their process of development and its modification.
Topics: Adult; Aged; Aged, 80 and over; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma; Carcinoma, Transitional Cell; Drug Synergism; Female; Humans; Male; Microscopy, Electron, Scanning; Middle Aged; Neoplasms, Experimental; Neoplasms, Multiple Primary; Rats; Urinary Bladder Neoplasms | 1989 |
Variation of the immunosystem by ciclosporin and keyhole-limpet hemocyanin--are there effects on chemically induced bladder carcinoma?
Topics: Animals; Butylhydroxybutylnitrosamine; Cyclosporins; Hemocyanins; Horseshoe Crabs; Immunization; Immunologic Surveillance; Immunosuppression Therapy; Male; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1989 |
[An experimental study on bladder carcinogenesis in dogs by N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) and its urinary metabolites].
Topics: Animals; Butylhydroxybutylnitrosamine; Dogs; Female; Gas Chromatography-Mass Spectrometry; Nitrosamines; Nitroso Compounds; Urinary Bladder Neoplasms | 1989 |
Effect of intravesical instillation of antitumor drugs in the development of N-butyl-N-(4-hydroxybutyl) nitrosamine-induced bladder tumors in rats.
Topics: Administration, Intravesical; Animals; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cisplatin; Doxorubicin; Female; Nitrosamines; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1989 |
[The biological properties and drug sensitivity of rat bladder cancer implanted into the subcutis and the bladder wall of rats].
Topics: Animals; Butylhydroxybutylnitrosamine; Drug Screening Assays, Antitumor; Female; Neoplasm Transplantation; Rats; Rats, Inbred ACI; Skin; Urinary Bladder; Urinary Bladder Neoplasms | 1989 |
[Urinary bladder carcinogenicity of BBN in beige mice (Chediak-Higashi disease model)].
Topics: Animals; Butylhydroxybutylnitrosamine; Chediak-Higashi Syndrome; Disease Models, Animal; Killer Cells, Natural; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Electron, Scanning; Nitrosamines; Urinary Bladder Neoplasms | 1989 |
Morphological changes of urothelial and intestinal mucosa after ureterosigmoidostomy during experimental urogenic carcinogenesis.
Topics: Adenocarcinoma; Animals; Butylhydroxybutylnitrosamine; Colon, Sigmoid; Epithelium; Female; Intestinal Mucosa; Intestinal Neoplasms; Rats; Rats, Inbred Strains; Ureterostomy; Urinary Bladder; Urinary Bladder Neoplasms | 1989 |
Changes in aldehyde dehydrogenase during rat urinary bladder carcinogenesis.
Topics: Aldehyde Dehydrogenase; Animals; Blotting, Western; Butylhydroxybutylnitrosamine; Carcinoma; Histocytochemistry; Isoenzymes; Liver; Papilloma; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1989 |
The role of urinary pH and sodium ion concentration in the promotion stage of two-stage carcinogenesis of the rat urinary bladder.
Topics: Animals; Bicarbonates; Butylhydroxybutylnitrosamine; Cocarcinogenesis; DNA; Hydrogen-Ion Concentration; Osmolar Concentration; Rats; Sodium; Sodium Bicarbonate; Urinary Bladder Neoplasms; Urine | 1988 |
Chromosomal characteristics and malignancy of urothelial cells from carcinogen-treated rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Chromosome Aberrations; FANFT; Karyotyping; Male; Mice; Mice, Nude; Neoplasm Transplantation; Polyploidy; Rats; Rats, Inbred F344; Tumor Cells, Cultured; Urinary Bladder Neoplasms | 1989 |
Lack of a modifying effect by the diuretic drug furosemide on the development of neoplastic lesions in rat two-stage urinary bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Transformation, Neoplastic; Cocarcinogenesis; Furosemide; Male; Nitrosamines; Polyuria; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1989 |
[Effect of thymus humoral factor on in vitro one-way mixed lymphocyte reaction responsiveness of thymus lymphocytes from rats during induction of a bladder tumor by BBN].
Topics: Animals; Butylhydroxybutylnitrosamine; Lymphocyte Culture Test, Mixed; Nitrosamines; Rats; Rats, Inbred Strains; T-Lymphocytes; Thymus Gland; Urinary Bladder Neoplasms | 1987 |
[Histological study of experimental bladder tumors].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Transformation, Neoplastic; Female; Papilloma; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1987 |
Sodium citrate: a promoter of bladder carcinogenesis.
Topics: Animals; Butylhydroxybutylnitrosamine; Citrates; Citric Acid; Cocarcinogenesis; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred F344; Sodium; Urinary Bladder Neoplasms | 1986 |
Delayed development of bladder cancer in male SD rats induced with N-nitroso-N-butyl-N-(4-hydroxybutyl)amine following concomitant administration of sodium 2-mercaptoethane sulfonate.
Topics: Animals; Butylhydroxybutylnitrosamine; Male; Mercaptoethanol; Mesna; Neoplasm Metastasis; Rats; Urinary Bladder Neoplasms | 1986 |
[Effect of intravesical instillation of the antitumor chemotherapeutic agents mitomycin C and cytosine arabinoside on rat bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl) nitrosamine].
Topics: Administration, Intravesical; Animals; Antineoplastic Combined Chemotherapy Protocols; Butylhydroxybutylnitrosamine; Cytarabine; Female; Mitomycin; Mitomycins; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1987 |
Urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)-nitrosamine in an analbuminemic congenic strain of rats with an ACI genetic background.
Topics: Animals; Butylhydroxybutylnitrosamine; Male; Rats; Rats, Inbred ACI; Rats, Inbred Strains; Rats, Mutant Strains; Serum Albumin; Urinary Bladder Neoplasms | 1986 |
Inhibition of N-butyl-N-(4-hydroxybutyl) nitrosamine-induced urinary bladder tumor in rats by alpha-difluoromethylornithine.
Topics: Animals; Butylhydroxybutylnitrosamine; Eflornithine; Male; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1987 |
Soft agar colony formation of bladder cells during carcinogenesis induced by N-butyl-N-(4-hydroxybutyl)nitrosamine and application to detection of bladder cancer promoters.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Colony-Forming Units Assay; Male; Nitrosamines; Rats; Tumor Stem Cell Assay; Urinary Bladder Neoplasms | 1987 |
Influence of disulfiram on the metabolism of the urinary bladder carcinogen N-butyl-N-(4-hydroxybutyl)nitrosamine in the rat.
Topics: Animals; Butylhydroxybutylnitrosamine; Carbon Dioxide; Carbon Radioisotopes; Disulfiram; Glucuronates; Hydroxylation; Liver; Male; Nitrosamines; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1987 |
Altered expression of immunohistochemically detected cytochrome P-450 component(s) in nitrosamine-induced rat urinary bladder lesion.
Topics: Animals; Butylhydroxybutylnitrosamine; Cytochrome P-450 Enzyme System; Enzyme Induction; Immunohistochemistry; Male; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Patterns of epithelial proliferation revealed by continuous administration of bromodeoxyuridine during urinary bladder carcinogenesis in rats.
Topics: Animals; Bromodeoxyuridine; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Epithelial Cells; Epithelium; Hyperplasia; Male; Nitrosamines; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Inhibition of N-butyl-N-(4-hydroxybutyl)nitrosamine-induced rat urinary bladder carcinogenesis by alpha-difluoromethylornithine.
Topics: Administration, Oral; Animals; Butylhydroxybutylnitrosamine; Eflornithine; Male; Nitrosamines; Osmolar Concentration; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1987 |
Effect of continuous intravesical infusion of low-concentrated mitomycin-C on bladder carcinogenesis in rats treated with N-butyl-N-4-hydroxybutyl-nitrosamine.
Topics: Administration, Intravesical; Animals; Butylhydroxybutylnitrosamine; Carcinoma, Papillary; Carcinoma, Transitional Cell; Catheters, Indwelling; Male; Mitomycin; Mitomycins; Rats; Rats, Inbred Strains; Time Factors; Urinary Bladder Neoplasms | 1988 |
Strain differences in N-butyl-N-(4-hydroxybutyl)nitrosamine bladder carcinogenesis in rats.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Cytochrome b Group; Cytochrome P-450 Enzyme System; Cytochromes b5; Disease Susceptibility; Epithelium; Neoplasms, Experimental; Nitrosamines; Organ Size; Rats; Rats, Inbred ACI; Rats, Inbred F344; Rats, Inbred Strains; Species Specificity; Urinary Bladder; Urinary Bladder Neoplasms | 1988 |
High susceptibility of an analbuminemic congenic strain of rats with an F344 genetic background to induced bladder cancer and its possible mechanism.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Membrane Permeability; Disease Susceptibility; Female; Immunoglobulin G; Male; Nitrosamines; Rats; Rats, Inbred F344; Serum Albumin; Species Specificity; Urinary Bladder Neoplasms | 1988 |
[Effect of intrabladder instillation of various anticancer agents on carcinogenesis in rat bladder].
Topics: Administration, Intravesical; Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Doxorubicin; Female; Hyperplasia; Mitomycin; Mitomycins; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1988 |
[The effect of lpr-gene on the accumulation of the number of piled layer in the bladder epithelium].
Topics: Animals; Autoimmune Diseases; Butylhydroxybutylnitrosamine; Epithelium; Genes, MHC Class II; Mice; Mice, Inbred Strains; Nitrosamines; Phenotype; Urinary Bladder; Urinary Bladder Neoplasms | 1988 |
Hyperbaric oxygenation for experimental bladder tumor. II. Hyperbaric oxygenation in combination with chemotherapy in N-butyl-N-(4-hydroxybutyl)nitrosamine-induced bladder tumors.
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Combined Modality Therapy; Doxorubicin; Female; Hyperbaric Oxygenation; Male; Nimustine; Nitrosourea Compounds; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1988 |
The statistical analysis of a carcinogen mixture experiment. II. Carcinogens with different target organs, N-methyl-N'-nitro-N-nitrosoguanidine, N-butyl-N-(4-hydroxybutyl)nitrosamine, dipentylnitrosamine, and nitrilotriacetic acid.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Data Interpretation, Statistical; Drug Interactions; Female; Kidney Neoplasms; Liver Neoplasms, Experimental; Male; Methylnitronitrosoguanidine; Nitrilotriacetic Acid; Nitrosamines; Rats; Rats, Inbred F344; Sex Factors; Stomach Neoplasms; Urinary Bladder Neoplasms | 1988 |
Summation effect of uracil on the two-stage and multistage models of urinary bladder carcinogenesis in F344 rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Body Weight; Butylated Hydroxyanisole; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cell Division; Cocarcinogenesis; Hyperplasia; Male; Nitrosamines; Papilloma; Rats; Rats, Inbred F344; Uracil; Urinary Bladder; Urinary Bladder Neoplasms | 1988 |
Effect of 1-hexylcarbamoyl-5-fluorouracil on development of rat urinary bladder tumor induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Antineoplastic Agents; Body Weight; Butylhydroxybutylnitrosamine; Fluorouracil; Male; Nitrosamines; Organ Size; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1988 |
[Ultrastructural study of experimental bladder tumor].
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1988 |
[The effect of complete Freund adjuvant on the development of bladder tumor induced by N-butyl-N-(4-hydroxybutyl) nitrosamine].
Topics: Animals; BCG Vaccine; Butylhydroxybutylnitrosamine; Female; Freund's Adjuvant; Mice; Mice, Inbred C57BL; Urinary Bladder Neoplasms | 1988 |
[Experimental model of urinary bladder tumor in rats for evaluation of chemotherapeutic agents].
Topics: Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Disease Models, Animal; Drug Screening Assays, Antitumor; Male; Rats; Rats, Inbred F344; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1988 |
[Animal models of bladder cancer].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Chemical Phenomena; Chemistry; Disease Models, Animal; Mice; Neoplasm Invasiveness; Neoplasm Metastasis; Precancerous Conditions; Rats; Urinary Bladder Neoplasms | 1988 |
[Measurement of DNA damage in urinary bladder epithelium by alkaline elution assay].
Topics: Animals; Butylhydroxybutylnitrosamine; DNA; DNA Damage; Epithelium; Male; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1988 |
Enhancement of chemically induced bladder carcinoma by cyclosporin A.
Topics: Animals; Butylhydroxybutylnitrosamine; Cyclosporins; Drug Synergism; Lymphocyte Activation; Male; Rats; Rats, Inbred Strains; T-Lymphocytes; Urinary Bladder Neoplasms | 1988 |
Activation of H-ras oncogene in rat bladder tumors induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Electrophoresis, Polyacrylamide Gel; Gene Expression Regulation; Genes, ras; Immunohistochemistry; Male; Nitrosamines; Rats; Rats, Inbred F344; Transfection; Urinary Bladder Neoplasms | 1988 |
Escherichia coli infection of the urinary bladder: induction of tumours in rats receiving nitrosamine precursors and augmentation of bladder carcinogenesis by N-nitrosobutyl (4-hydroxybutyl)amine.
Topics: Amines; Animals; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Cystitis; Escherichia coli Infections; Female; Nitrates; Nitrosamines; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1987 |
Effects of urinary crystals induced by acetazolamide, uracil, and diethylene glycol on urinary bladder carcinogenesis in N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated rats.
Topics: Acetazolamide; Animals; Butylhydroxybutylnitrosamine; Crystallization; Dose-Response Relationship, Drug; Ethylene Glycols; Male; Nitrosamines; Rats; Uracil; Urinary Bladder Neoplasms; Urinary Calculi | 1988 |
Assessment of L-ascorbic acid requirement for prolonged survival in ODS rats and their susceptibility to urinary bladder carcinogenesis by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Ascorbic Acid; Ascorbic Acid Deficiency; Butylhydroxybutylnitrosamine; Male; Rats; Urinary Bladder Neoplasms | 1988 |
Combined effects of L-ascorbic acid, citric acid or their sodium salts on tumor induction by N-butyl-N-(4-hydroxybutyl)nitrosamine or N-ethyl-N-(4-hydroxybutyl)nitrosamine in the rat urinary bladder.
Topics: Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Citrates; Citric Acid; Diethylnitrosamine; Drug Interactions; Hydrogen-Ion Concentration; Male; Nitrosamines; Organ Size; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1988 |
Nonspecific esterase reaction in hyperplastic urinary bladder epithelium induced by administration of N-butyl-N-(4-hydroxybutyl)nitrosamine, freezing and formalin instillation in rats.
Topics: Animals; Biomarkers, Tumor; Butylhydroxybutylnitrosamine; Carboxylesterase; Carboxylic Ester Hydrolases; Epithelium; Formaldehyde; Freezing; Hyperplasia; Male; Precancerous Conditions; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1988 |
Lipid composition of the plasma membrane isolated from normal and precancerous rat bladder epithelium.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Membrane; Epithelium; Fatty Acids; Male; Membrane Lipids; Microscopy, Electron; Phosphatidylcholines; Phosphatidylethanolamines; Phospholipids; Precancerous Conditions; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Effects of single chemotherapeutic agents on development of urinary bladder tumor induced by N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN) in rats.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Injections, Intraperitoneal; Male; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Aging and urinary bladder carcinogenesis induced in rats by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Aging; Animals; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Female; Male; Nitrosamines; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1987 |
Marked reduction in percentage of rosette-forming thymocytes of rats during induction of bladder tumors and restorative effect of thymosin in vitro.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Differentiation; Female; Guinea Pigs; In Vitro Techniques; Molecular Weight; Rats; Rats, Inbred Strains; Rosette Formation; T-Lymphocytes; Thymosin; Urinary Bladder Neoplasms | 1986 |
[Study on rosette formation of thymus lymphocytes in the rat treated with BBN inducing urinary bladder cancer. Effect of the thymus humoral factor in vitro].
Topics: Animals; Butylhydroxybutylnitrosamine; Female; In Vitro Techniques; Rats; Rats, Inbred Strains; Rosette Formation; T-Lymphocytes; Thymus Hormones; Urinary Bladder Neoplasms | 1986 |
Reduction in responsiveness of thymocytes to phytohemagglutinin during bladder tumor induction and restorative effects of thymosin fraction 5 in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Lymphocyte Activation; Phytohemagglutinins; Precancerous Conditions; Rats; Rats, Inbred Strains; T-Lymphocytes; Thymosin; Thymus Gland; Time Factors; Urinary Bladder Neoplasms | 1987 |
Influences of strain and diet on the promoting effects of sodium L-ascorbate in two-stage urinary bladder carcinogenesis in rats.
Topics: Animals; Ascorbic Acid; Butylhydroxybutylnitrosamine; Carcinoma; Cocarcinogenesis; Diet; Hydrogen-Ion Concentration; Rats; Rats, Inbred F344; Rats, Inbred Lew; Sodium; Urinary Bladder Neoplasms | 1987 |
Modification by alpha-tocopherol, propyl gallate and tertiary butylhydroquinone of urinary bladder carcinogenesis in Fischer 344 rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Gallic Acid; Hydroquinones; Male; Nitrosamines; Propyl Gallate; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms; Vitamin E | 1987 |
[Experimental study on cystitis as a risk factor in urinary bladder carcinoma--effect of inflammation on N-butyl-N-(4-hydroxybutyl) nitrosamine (BBN)-induced rat urinary bladder carcinogenesis].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cystitis; Nitrosamines; Rats; Risk; Urinary Bladder Neoplasms | 1986 |
[Effect of partial cystectomy on BBN-induced rat bladder cancer].
Topics: Adult; Aged; Aged, 80 and over; Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Female; Humans; Male; Middle Aged; Neoplasm Invasiveness; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms; Wound Healing | 1987 |
Development of an experimental model for studying bladder carcinogen metabolism using the isolated rat urinary bladder.
Topics: Animals; Biotransformation; Butylhydroxybutylnitrosamine; Carcinogens; Glucuronates; Male; Nitrosamines; Rats; Time Factors; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Effect of phenacetin and caffeine on N-butyl-N-(4-hydroxybutyl)-nitrosamine-initiated urothelial carcinogenesis in rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Caffeine; Carcinoma, Transitional Cell; Cocarcinogenesis; Cyclophosphamide; Female; Phenacetin; Rats; Rats, Inbred Strains; Regeneration; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Promotion by L-ascorbic acid of urinary bladder carcinogenesis in rats under conditions of increased urinary K ion concentration and pH.
Topics: Animals; Ascorbic Acid; Body Weight; Butylhydroxybutylnitrosamine; Hydrogen-Ion Concentration; Male; Organ Size; Potassium; Rats; Rats, Inbred F344; Sodium; Urinary Bladder Neoplasms | 1987 |
[Distribution and phototoxicity of hematoporphyrin derivative in experimentally induced rat bladder tumors].
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Hematoporphyrin Photoradiation; Hematoporphyrins; Laser Therapy; Photochemotherapy; Rats; Rats, Inbred Strains; Tissue Distribution; Urinary Bladder Neoplasms | 1987 |
Strong promoting activity of reversible uracil-induced urolithiasis on urinary bladder carcinogenesis in rats initiated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Squamous Cell; Carcinoma, Transitional Cell; Cocarcinogenesis; Male; Nitrosamines; Rats; Rats, Inbred F344; Uracil; Urinary Bladder Calculi; Urinary Bladder Neoplasms | 1987 |
[Photodynamic therapy (PDT) of bladder cancer in the rat].
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Hematoporphyrin Photoradiation; Hematoporphyrins; Papilloma; Photochemotherapy; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1986 |
Promoting effects of various agents in rat urinary bladder carcinogenesis initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Acetaminophen; Allopurinol; Aminocaproates; Animals; Biphenyl Compounds; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Hydrogen-Ion Concentration; Indomethacin; Male; Nitrosamines; Rats; Rats, Inbred F344; Sodium; Urinary Bladder; Urinary Bladder Calculi; Urinary Bladder Neoplasms | 1986 |
Strain differences in mice with invasive bladder carcinomas induced by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; Female; Mice; Mice, Inbred Strains; Nitrosamines; Species Specificity; Urinary Bladder; Urinary Bladder Neoplasms | 1986 |
Promoting effect of sodium chloride in 2-stage urinary bladder carcinogenesis in rats initiated by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinoma; Cocarcinogenesis; Hyperplasia; Male; Nitrosamines; Papilloma; Rats; Rats, Inbred F344; Sodium Chloride; Urinary Bladder; Urinary Bladder Neoplasms | 1986 |
Induction of high-grade, high-stage carcinomas in the rat urinary bladder.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; DNA; DNA, Neoplasm; Dose-Response Relationship, Drug; Epithelium; Flow Cytometry; Hyperplasia; Methylnitrosourea; Neoplasm Transplantation; Nitrosamines; Rats; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Dose-dependent effects of butylated hydroxyanisole, butylated hydroxytoluene and ethoxyquin for promotion of bladder carcinogenesis in N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated, unilaterally ureter-ligated rats.
Topics: Animals; Body Weight; Butylated Hydroxyanisole; Butylated Hydroxytoluene; Butylhydroxybutylnitrosamine; Cocarcinogenesis; Dose-Response Relationship, Drug; Ethoxyquin; Ligation; Male; Quinolines; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Scanning electron microscopy of changes in the urinary bladder in dogs treated with N-butyl-N-(4-hydroxybutyl)nitrosamine (BBN).
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Disease Models, Animal; Dogs; Epithelium; Female; Hyperplasia; Nitrosamines; Urinary Bladder; Urinary Bladder Neoplasms | 1987 |
Modulation of carcinogenesis in the urinary bladder by retinoids.
Topics: Animals; Butylhydroxybutylnitrosamine; Cell Transformation, Neoplastic; Disease Models, Animal; Epithelium; Mice; Mice, Inbred Strains; Rats; Rats, Inbred F344; Retinoids; Time Factors; Urinary Bladder Neoplasms | 1985 |
Trisodium nitriloacetate monohydrate: promoting effect in urinary bladder carcinogenesis in rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Acetates; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Drug Synergism; Hyperplasia; Male; Nitrilotriacetic Acid; Nitrosamines; Organ Size; Papilloma; Rats; Rats, Inbred Strains; Urinary Bladder Neoplasms | 1985 |
Thymus lymphocytes in rats during induction of bladder tumors and effects of thymosin fraction 5 in vitro.
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Lymphocyte Activation; Lymphocytes; Nitrosamines; Rats; Rats, Inbred Strains; Thymosin; Thymus Gland; Urinary Bladder Neoplasms | 1985 |
The effects of catechol on the urinary bladder of rats treated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Catechols; Cocarcinogenesis; Male; Nitrosamines; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1985 |
[Effect of UFT on urinary bladder tumors in rats induced by N-butyl-N-(4-hydroxybutyl)nitrosamine].
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Butylhydroxybutylnitrosamine; Drug Administration Schedule; Male; Rats; Rats, Inbred F344; Tegafur; Uracil; Urinary Bladder Neoplasms | 1985 |
Dose-dependent promoting effect of trisodium nitrilotriacetate monohydrate on urinary bladder carcinogenesis in Wistar rats pretreated with N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Acetates; Animals; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Carcinoma, Transitional Cell; Dose-Response Relationship, Drug; Kidney; Male; Nitrilotriacetic Acid; Organ Size; Papilloma; Precancerous Conditions; Rats; Rats, Inbred Strains; Urinary Bladder; Urinary Bladder Neoplasms | 1985 |
Promoting effect of trisodium nitrilotriacetate monohydrate on urinary bladder carcinogenesis in rats.
Topics: Acetates; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Male; Nitrilotriacetic Acid; Papilloma; Precancerous Conditions; Rats; Rats, Inbred F344; Time Factors; Urinary Bladder Neoplasms | 1985 |
Short-term screening of promoters of bladder carcinogenesis in N-butyl-N-(4-hydroxybutyl)nitrosamine-initiated, unilaterally ureter-ligated rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinogens; Ligation; Male; Papilloma; Precancerous Conditions; Rats; Rats, Inbred F344; Time Factors; Ureter; Urinary Bladder Neoplasms | 1985 |
Correlation of results of agglutination assays with concanavalin A and carcinogenesis experiments on promoters of bladder cancer.
Topics: Agglutination Tests; Animals; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Concanavalin A; Drug Evaluation, Preclinical; In Vitro Techniques; Male; Rats; Rats, Inbred F344; Urinary Bladder Neoplasms | 1985 |
Roles of urinary sodium ion concentration and pH in promotion by ascorbic acid of urinary bladder carcinogenesis in rats.
Topics: Animals; Ascorbic Acid; Bicarbonates; Body Weight; Butylhydroxybutylnitrosamine; Dehydroascorbic Acid; Hydrogen-Ion Concentration; Male; Rats; Rats, Inbred F344; Sodium; Urinary Bladder; Urinary Bladder Neoplasms | 1986 |
Sequential changes of mouse bladder epithelium during induction of invasive carcinomas by N-butyl-N-(4-hydroxybutyl)nitrosamine.
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma; Carcinoma in Situ; Epithelium; Female; Mice; Neoplasm Invasiveness; Nitrosamines; Urinary Bladder; Urinary Bladder Neoplasms | 1986 |
Effect of N-nitroso-n-butyl-(4-hydroxybutyl)amine exposure on the changes in mineral disposition caused by trisodium nitrilotriacetate.
Topics: Acetates; Animals; Butylhydroxybutylnitrosamine; Calcium; Cocarcinogenesis; Dose-Response Relationship, Drug; Male; Minerals; Nitrilotriacetic Acid; Nitrosamines; Organ Size; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms; Zinc | 1986 |
[Coagulation and fibrinolysis system in bladder tumor. 2. Effect of fibrinolytic and anti-fibrinolytic agents on BBN-induced rat bladder tumor].
Topics: Animals; Butylhydroxybutylnitrosamine; Carcinoma, Transitional Cell; Cyclohexanecarboxylic Acids; Male; Nitrosamines; Rats; Rats, Inbred Strains; Tranexamic Acid; Urinary Bladder Neoplasms; Urokinase-Type Plasminogen Activator | 1985 |
Pathological analysis of the carcinogenicity of sodium o-phenylphenate and o-phenylphenol.
Topics: Animals; Biphenyl Compounds; Body Weight; Butylhydroxybutylnitrosamine; Carcinogens; Cocarcinogenesis; Hyperplasia; Male; Microscopy, Electron, Scanning; Microvilli; Organ Size; Papilloma; Rats; Rats, Inbred F344; Urinary Bladder; Urinary Bladder Neoplasms | 1985 |
Long-term effect of 2-hydroxyethyl retinamide on urinary bladder carcinogenesis and tumor transplantation in Fischer 344 rats.
Topics: Animals; Butylhydroxybutylnitrosamine; Female; Neoplasm Transplantation; Rats; Rats, Inbred F344; Time Factors; Tretinoin; Urinary Bladder Neoplasms | 1985 |