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butylbenzyl phthalate and Pregnancy

butylbenzyl phthalate has been researched along with Pregnancy in 31 studies

spatozoate: structure in first source

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Recent cross-sectional studies suggest a link between butylbenzyl phthalate (BBzP) in house dust and childhood eczema."7.78Prenatal exposure to butylbenzyl phthalate and early eczema in an urban cohort. ( Calafat, AM; Chen, Q; Goldstein, IF; Just, AC; Miller, RL; Perera, FP; Perzanowski, MS; Rundle, AG; Whyatt, RM, 2012)
"Recent cross-sectional studies suggest a link between butylbenzyl phthalate (BBzP) in house dust and childhood eczema."3.78Prenatal exposure to butylbenzyl phthalate and early eczema in an urban cohort. ( Calafat, AM; Chen, Q; Goldstein, IF; Just, AC; Miller, RL; Perera, FP; Perzanowski, MS; Rundle, AG; Whyatt, RM, 2012)
" Rats were dosed during pregnancy with antiandrogens singly or in pairs at dosage levels equivalent to about one half of the ED50 for hypospadias or epididymal agenesis."2.45Cumulative effects of in utero administration of mixtures of "antiandrogens" on male rat reproductive development. ( Furr, JR; Gray, LE; Hotchkiss, AK; Howdeshell, KL; Lambright, CR; Rider, CV; Wilson, VS, 2009)
"The prevalence of language delay was 10."1.48Association of Prenatal Phthalate Exposure With Language Development in Early Childhood. ( Barrett, ES; Bornehag, CG; Bush, NR; Evans, SF; Lindh, C; Nguyen, RHN; Reichenberg, A; Sathyanarayana, S; Swan, SH; Unenge Hallerback, M; Wikström, S, 2018)
" single-day exposure dose-response relationships."1.35The role of developmental toxicity studies in acute exposure assessments: analysis of single-day vs. multiple-day exposure regimens. ( Davis, A; Foureman, GL; Gift, JS; Narotsky, MG; Woodall, GM, 2009)
" We characterized the dose-response effects of six individual phthalates (BBP, DBP, DEHP, diethyl phthalate [DEP], diisobutyl phthalate [DiBP], and dipentyl phthalate [DPP]) on gestation day (GD) 18 testicular testosterone production following exposure of Sprague-Dawley rats on GD 8-18."1.35A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner. ( Blystone, CR; Furr, J; Gray, LE; Hotchkiss, AK; Howdeshell, KL; Lambright, CR; Rider, CV; Wilson, VS, 2008)
" In the parental animals, the no observed effect level (NOEL) and the no observed adverse effect level (NOAEL) were less than 100 mg/kg/day, and no serious effects on the reproductive capacity were induced at doses less than 200 mg/kg/day."1.33A two-generation reproductive toxicity study of butyl benzyl phthalate in rats. ( Aso, S; Ehara, H; Hosyuyama, S; Minobe, Y; Miyata, K; Shiraishi, K; Umano, T, 2005)
" In general, consideration of the dose-response curves for the antiandrogenic effects suggests that these responses were dose additive rather than synergistic responses."1.32A mixture of the "antiandrogens" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion. ( Furr, J; Gray, LE; Hotchkiss, AK; Lambright, C; Ostby, JS; Parks-Saldutti, LG; Vandenbergh, JG, 2004)
" While only DEHP treatment reduced maternal weight gain during the entire dosing period by about 15 g, both DEHP and DINP reduced pregnancy weight gain to GD 21 by 24 g and 14 g, respectively."1.31Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat. ( Furr, J; Gray, LE; Ostby, J; Parks, L; Price, M; Veeramachaneni, DN, 2000)
"n-Butyl benzyl phthalate (BBP) and di-n-butyl phthalate (DBP) were evaluated and compared for their developmental toxic potential."1.29Comparative developmental toxicity of n-butyl benzyl phthalate and di-n-butyl phthalate in rats. ( Amano, H; Ema, M; Kurosaka, R; Ogawa, Y, 1995)
" Pregnant rats were given BBP at a dosage of 0, 0."1.28Evaluation of the teratogenic potential of the plasticizer butyl benzyl phthalate in rats. ( Ema, M; Itami, T; Kawasaki, H; Murai, T, 1990)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's9 (29.03)18.2507
2000's12 (38.71)29.6817
2010's7 (22.58)24.3611
2020's3 (9.68)2.80

Authors

AuthorsStudies
Shan, D1
Zhang, T1
Li, L1
Sun, Y1
Wang, D1
Li, Y1
Yang, Z1
Cui, K1
Wu, S1
Jin, L1
Hong, B1
Shang, X1
Wang, Q1
Mogus, JP1
Matouskova, K1
Clark, ZW1
Jerry, DJ1
Vandenberg, LN1
Elter, E1
Wagner, M1
Buchenauer, L1
Bauer, M1
Polte, T1
Bornehag, CG1
Lindh, C1
Reichenberg, A1
Wikström, S1
Unenge Hallerback, M1
Evans, SF1
Sathyanarayana, S1
Barrett, ES1
Nguyen, RHN1
Bush, NR1
Swan, SH1
Li, X1
Liu, L1
Wang, H1
Zhang, X1
Xiao, T1
Shen, H1
Ahmad, R1
Gautam, AK1
Verma, Y1
Sedha, S1
Kumar, S1
DeBartolo, D1
Jayatilaka, S1
Yan Siu, N1
Rose, M1
Ramos, RL1
Betz, AJ1
Jeddi, MZ1
Rastkari, N1
Ahmadkhaniha, R1
Yunesian, M1
Zhuang, MZ1
Li, YF1
Li, T1
Rider, CV2
Wilson, VS3
Howdeshell, KL2
Hotchkiss, AK3
Furr, JR1
Lambright, CR2
Gray, LE5
Davis, A1
Gift, JS1
Woodall, GM1
Narotsky, MG1
Foureman, GL1
Sumner, S1
Snyder, R1
Burgess, J1
Myers, C1
Tyl, R1
Sloan, C1
Fennell, T1
Moral, R2
Santucci-Pereira, J1
Wang, R2
Russo, IH2
Lamartiniere, CA2
Russo, J2
Just, AC1
Whyatt, RM1
Perzanowski, MS1
Calafat, AM1
Perera, FP1
Goldstein, IF1
Chen, Q1
Rundle, AG1
Miller, RL1
Lambright, C2
Furr, J4
Ostby, J2
Wood, C1
Held, G1
Parks-Saldutti, LG1
Ostby, JS1
Vandenbergh, JG1
Aso, S1
Ehara, H1
Miyata, K1
Hosyuyama, S1
Shiraishi, K1
Umano, T1
Minobe, Y1
Mailo, DA1
Blystone, CR1
Piersma, AH1
Verhoef, A1
Dortant, PM1
Ema, M6
Kurosaka, R1
Amano, H1
Ogawa, Y1
Itami, T5
Kawasaki, H5
Sharpe, RM1
Fisher, JS1
Millar, MM1
Jobling, S1
Sumpter, JP1
Ashby, J1
Tinwell, H1
Lefevre, PA1
Odum, J1
Paton, D1
Millward, SW1
Tittensor, S1
Brooks, AN1
Price, M1
Veeramachaneni, DN1
Parks, L1
Uriu-Adams, JY1
Kevin Reece, C1
Nguyen, LK1
Horvath, BJ1
Nair, R1
Barter, RA1
Keen, CL1
Götz, F1
Thieme, S1
Dörner, G1
Murai, T1

Reviews

1 review available for butylbenzyl phthalate and Pregnancy

ArticleYear
Cumulative effects of in utero administration of mixtures of "antiandrogens" on male rat reproductive development.
    Toxicologic pathology, 2009, Volume: 37, Issue:1

    Topics: Androgen Antagonists; Animals; Bridged Bicyclo Compounds; Complex Mixtures; Dibutyl Phthalate; Dieth

2009

Other Studies

30 other studies available for butylbenzyl phthalate and Pregnancy

ArticleYear
Cumulative risk assessment of dietary exposure to phthalates in pregnant women in Beijing, China.
    Environmental science and pollution research international, 2022, Volume: 29, Issue:49

    Topics: Beijing; China; Dibutyl Phthalate; Dietary Exposure; Diethylhexyl Phthalate; Environmental Exposure;

2022
Effects of butyl benzyl phthalate exposure during pregnancy and lactation on the post-involution mammary gland.
    Reproductive toxicology (Elmsford, N.Y.), 2023, Volume: 122

    Topics: Animals; Female; Lactation; Male; Mammary Glands, Animal; Mice; Phthalic Acids; Pregnancy; Receptors

2023
Phthalate Exposure During the Prenatal and Lactational Period Increases the Susceptibility to Rheumatoid Arthritis in Mice.
    Frontiers in immunology, 2020, Volume: 11

    Topics: Animals; Arthritis, Experimental; Arthritis, Rheumatoid; Disease Susceptibility; Female; Lactation;

2020
Association of Prenatal Phthalate Exposure With Language Development in Early Childhood.
    JAMA pediatrics, 2018, 12-01, Volume: 172, Issue:12

    Topics: Adolescent; Adult; Child, Preschool; Dibutyl Phthalate; Environmental Exposure; Female; Humans; Lang

2018
Phthalate exposure and cumulative risk in a Chinese newborn population.
    Environmental science and pollution research international, 2019, Volume: 26, Issue:8

    Topics: Adult; Asian People; Child; China; Cross-Sectional Studies; Dibutyl Phthalate; Environmental Exposur

2019
Effects of in utero di-butyl phthalate and butyl benzyl phthalate exposure on offspring development and male reproduction of rat.
    Environmental science and pollution research international, 2014, Volume: 21, Issue:4

    Topics: 17-Hydroxysteroid Dehydrogenases; Animals; Body Weight; Dibutyl Phthalate; Female; Kidney; Liver; Ma

2014
Perinatal exposure to benzyl butyl phthalate induces alterations in neuronal development/maturation protein expression, estrogen responses, and fear conditioning in rodents.
    Behavioural pharmacology, 2016, Volume: 27, Issue:1

    Topics: Animal Feed; Animals; Brain; Cell Movement; Estrogens; Fear; Female; Learning Disabilities; Male; Me

2016
Endocrine disruptor phthalates in bottled water: daily exposure and health risk assessment in pregnant and lactating women.
    Environmental monitoring and assessment, 2016, Volume: 188, Issue:9

    Topics: Adult; Dibutyl Phthalate; Drinking Water; Endocrine Disruptors; Environmental Monitoring; Female; Ga

2016
[Effects of butyl benzyl phthalate on neurobehavioral development of rats].
    Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases, 2008, Volume: 26, Issue:5

    Topics: Animals; Behavior, Animal; Dose-Response Relationship, Drug; Female; Growth and Development; Male; M

2008
The role of developmental toxicity studies in acute exposure assessments: analysis of single-day vs. multiple-day exposure regimens.
    Regulatory toxicology and pharmacology : RTP, 2009, Volume: 54, Issue:2

    Topics: Animals; Benchmarking; Congenital Abnormalities; Dose-Response Relationship, Drug; Embryo Loss; Embr

2009
Metabolomics in the assessment of chemical-induced reproductive and developmental outcomes using non-invasive biological fluids: application to the study of butylbenzyl phthalate.
    Journal of applied toxicology : JAT, 2009, Volume: 29, Issue:8

    Topics: Abnormalities, Drug-Induced; Animals; Endocrine Disruptors; Female; Fetal Development; Magnetic Reso

2009
In utero exposure to butyl benzyl phthalate induces modifications in the morphology and the gene expression profile of the mammary gland: an experimental study in rats.
    Environmental health : a global access science source, 2011, Jan-17, Volume: 10, Issue:1

    Topics: Animals; Female; Fetus; Gene Expression Profiling; Mammary Glands, Animal; Phthalic Acids; Polymeras

2011
Prenatal exposure to butylbenzyl phthalate and early eczema in an urban cohort.
    Environmental health perspectives, 2012, Volume: 120, Issue:10

    Topics: Adult; Air Pollutants; Air Pollution, Indoor; Allergens; Black or African American; Child, Preschool

2012
Phthalate ester-induced gubernacular lesions are associated with reduced insl3 gene expression in the fetal rat testis.
    Toxicology letters, 2004, Feb-02, Volume: 146, Issue:3

    Topics: Abnormalities, Drug-Induced; Androgen Receptor Antagonists; Animals; Dibutyl Phthalate; Diethylhexyl

2004
A mixture of the "antiandrogens" linuron and butyl benzyl phthalate alters sexual differentiation of the male rat in a cumulative fashion.
    Biology of reproduction, 2004, Volume: 71, Issue:6

    Topics: Anal Canal; Androgen Antagonists; Animals; Animals, Newborn; Dose-Response Relationship, Drug; Femal

2004
A two-generation reproductive toxicity study of butyl benzyl phthalate in rats.
    The Journal of toxicological sciences, 2005, Volume: 30 Spec No.

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Endocrine Disruptors; Female; Male;

2005
The plasticizer butyl benzyl phthalate induces genomic changes in rat mammary gland after neonatal/prepubertal exposure.
    BMC genomics, 2007, Dec-06, Volume: 8

    Topics: Animals; Animals, Newborn; Cell Proliferation; Female; Gene Expression Profiling; Genome; Mammary Gl

2007
A mixture of five phthalate esters inhibits fetal testicular testosterone production in the sprague-dawley rat in a cumulative, dose-additive manner.
    Toxicological sciences : an official journal of the Society of Toxicology, 2008, Volume: 105, Issue:1

    Topics: Animals; Body Weight; Dibutyl Phthalate; Diethylhexyl Phthalate; Dose-Response Relationship, Drug; F

2008
Evaluation of the OECD 421 reproductive toxicity screening test protocol using butyl benzyl phthalate.
    Toxicology, 1995, May-23, Volume: 99, Issue:3

    Topics: Animals; Body Weight; Eating; Evaluation Studies as Topic; Female; Fertility; International Agencies

1995
Comparative developmental toxicity of n-butyl benzyl phthalate and di-n-butyl phthalate in rats.
    Archives of environmental contamination and toxicology, 1995, Volume: 28, Issue:2

    Topics: Abnormalities, Drug-Induced; Animals; Dibutyl Phthalate; Embryo Loss; Embryonic and Fetal Developmen

1995
Teratogenic phase specificity of butyl benzyl phthalate in rats.
    Toxicology, 1993, Mar-30, Volume: 79, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Dose-Response Relationship, Drug; Female; Fetus; Male; Phthali

1993
Gestational and lactational exposure of rats to xenoestrogens results in reduced testicular size and sperm production.
    Environmental health perspectives, 1995, Volume: 103, Issue:12

    Topics: Animals; Animals, Newborn; Animals, Suckling; Diethylstilbestrol; Estrogens; Estrogens, Non-Steroida

1995
Normal sexual development of rats exposed to butyl benzyl phthalate from conception to weaning.
    Regulatory toxicology and pharmacology : RTP, 1997, Volume: 26, Issue:1 Pt 1

    Topics: Animals; Body Weight; Diethylstilbestrol; Drinking; Embryonic and Fetal Development; Female; Follicl

1997
Perinatal exposure to the phthalates DEHP, BBP, and DINP, but not DEP, DMP, or DOTP, alters sexual differentiation of the male rat.
    Toxicological sciences : an official journal of the Society of Toxicology, 2000, Volume: 58, Issue:2

    Topics: Abnormalities, Drug-Induced; Androgen Antagonists; Animals; Diethylhexyl Phthalate; Female; Fetus; H

2000
Effect of butyl benzyl phthalate on reproduction and zinc metabolism.
    Toxicology, 2001, Feb-21, Volume: 159, Issue:1-2

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Calcification, Physiologic; Eating; Female; Metal

2001
Female infertility--effect of perinatal xenoestrogen exposure on reproductive functions in animals and humans.
    Folia histochemica et cytobiologica, 2001, Volume: 39 Suppl 2

    Topics: Adolescent; Adult; Animals; Breast Neoplasms; DDT; Diethylstilbestrol; Estrogens, Non-Steroidal; Est

2001
Effect of period of exposure on the developmental toxicity of butyl benzyl phthalate in rats.
    Journal of applied toxicology : JAT, 1992, Volume: 12, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Corpus Luteum; Eating; Embryo Implantation; Em

1992
Teratogenic evaluation of butyl benzyl phthalate in rats by gastric intubation.
    Toxicology letters, 1992, Volume: 61, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Eating; Embryo, Mammalian; Female; Fetal Resorpti

1992
Embryolethality and teratogenicity of butyl benzyl phthalate in rats.
    Journal of applied toxicology : JAT, 1992, Volume: 12, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Body Weight; Diet; Eating; Embryo, Mammalian; Female; Fetus; P

1992
Evaluation of the teratogenic potential of the plasticizer butyl benzyl phthalate in rats.
    Journal of applied toxicology : JAT, 1990, Volume: 10, Issue:5

    Topics: Animals; Body Weight; Diet; Female; Fetus; Growth; Organ Size; Phthalic Acids; Plasticizers; Pregnan

1990