butorphanol has been researched along with Substance Withdrawal Syndrome in 48 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 10 (20.83) | 18.7374 |
1990's | 25 (52.08) | 18.2507 |
2000's | 12 (25.00) | 29.6817 |
2010's | 1 (2.08) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Howes, JF; Kotick, MP; Osgood, PF; Polazzi, JO; Razdan, RK; Schut, RN; Villarreal, JE | 1 |
Bousquet, AR; Howes, JF; Kotick, MP; Polazzi, JO | 1 |
Kotick, MP; Leland, DL | 1 |
Grechko, OY; Litvinov, LA; Rashchenko, AI; Shtareva, DM; Spasov, AA | 1 |
Jang, CG; Lee, KW; Lee, SY; Tian, YH; You, IJ | 1 |
Amagasa, S; Igarashi, A; Sato, M; Yokoo, N | 1 |
Fan, LW; Ho, IK; Ma, T; Rockhold, RW; Tanaka, S; Tien, LT | 1 |
Ho, IK; Rockhold, RW; Sinchaisuk, S | 1 |
Jang, SY; Kim, Y; Oh, S | 1 |
Fan, LW; Ho, IK; Ma, T; Park, Y; Rockhold, RW; Sasaki, K; Tanaka, S; Tien, LT | 2 |
Chudapongse, N; Fan, LW; Ho, IK; Ma, T; Rockhold, RW; Sinchaisuk, S; Tanaka, S; Tien, LT | 1 |
Jang, S; Kim, DS; Lim, HK; Oh, S | 1 |
Fan, LW; Ho, IK; Liu-Chen, LY; Park, Y; Rockhold, RW; Tanaka, S; Tien, LT | 1 |
Jang, CG; Lee, SY | 1 |
Khazan, N; Steinfels, GF; Young, GA | 1 |
Feng, Y; Ho, IK; Tokuyama, S; Wakabayashi, H | 2 |
Feng, YZ; Ho, IK; Rockhold, RW; Zhang, T | 1 |
Fukase, H; Fukuzaki, K; Koja, T; Lukas, SE; Nagata, R | 1 |
Ho, IK; Hoskins, B; Jaw, SP; Makimura, M; Oh, KW | 2 |
Ho, IK; Hoskins, B; Jaw, SP; Makimura, M | 1 |
Ho, IK; Hoskins, B; Jaw, SP | 1 |
Ho, IK; Hoskins, B; Tokuyama, S; Wakabayashi, H | 1 |
Ho, IK; Tokuyama, S | 2 |
Feng, YZ; Ho, IK; Rockhold, RW; Tokuyama, S; Zhang, T; Zhu, H | 1 |
Ho, IK; Hoshi, K; Ma, T | 1 |
Ho, IK; Hoshi, K; Ma, T; Oh, S | 1 |
Feng, Y; Ho, IK; Rockhold, RW | 1 |
Feng, YZ; Ho, IK; Hoshi, K; Rockhold, RW; Tokuyama, S | 1 |
Ho, IK; Rockhold, RW; Zhu, H | 1 |
Feng, YZ; Ho, IK; Tokuyama, S; Wakabayashi, H; Zhu, H | 1 |
He, Z; Ho, IK; Tsang, BK; Wongchanapai, W | 1 |
Ho, IK; Jang, CG; Rockhold, RW | 1 |
Glatt, W | 1 |
Ho, IK; Jang, C; Park, Y; Rockhold, RW | 1 |
Greenwald, MK; Stitzer, ML | 1 |
Chung, MW; Ho, IK; Kim, JI; Oh, S | 1 |
Ho, IK; Horan, P | 2 |
Bigelow, GE; Liebson, IA; Preston, KL | 2 |
Naulty, JS; Weintraub, SJ | 1 |
Brown, GR | 1 |
Gmerek, DE; Woods, JH | 1 |
2 review(s) available for butorphanol and Substance Withdrawal Syndrome
Article | Year |
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Glutamate in opioid dependence.
Topics: Analgesics, Opioid; Animals; Butorphanol; Glutamic Acid; Locus Coeruleus; Microdialysis; Opioid-Related Disorders; Rats; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 1997 |
The role of glutamate in physical dependence on opioids.
Topics: Analgesics, Opioid; Animals; Butorphanol; Disease Models, Animal; Glutamic Acid; Locus Coeruleus; Neurons, Afferent; Opioid-Related Disorders; Rats; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 1998 |
3 trial(s) available for butorphanol and Substance Withdrawal Syndrome
Article | Year |
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A new method for detoxifying opioid-dependent patients.
Topics: Administration, Intranasal; Adult; Aged; Analgesics, Opioid; Butorphanol; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Narcotic Antagonists; Opioid-Related Disorders; Substance Withdrawal Syndrome; Treatment Outcome | 1999 |
Butorphanol agonist effects and acute physical dependence in opioid abusers: comparison with morphine.
Topics: Adult; Arousal; Brain; Butorphanol; Dose-Response Relationship, Drug; Double-Blind Method; Euphoria; Heroin Dependence; Humans; Hypnotics and Sedatives; Lorazepam; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 1998 |
Butorphanol-precipitated withdrawal in opioid-dependent human volunteers.
Topics: Adult; Butorphanol; Cognition; Double-Blind Method; Humans; Hydromorphone; Injections, Intramuscular; Male; Methadone; Morphinans; Naloxone; Opioid-Related Disorders; Psychomotor Performance; Substance Withdrawal Syndrome | 1988 |
43 other study(ies) available for butorphanol and Substance Withdrawal Syndrome
Article | Year |
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Analgesic narcotic antagonists. 2. 8-Alkymorphinan-6-ones.
Topics: Acetates; Analgesics; Animals; Haplorhini; Humans; Mice; Morphinans; Morphine Dependence; Narcotic Antagonists; Rats; Reaction Time; Structure-Activity Relationship; Substance Withdrawal Syndrome; Substance-Related Disorders | 1980 |
Analgesic narcotic antagonists. 9. 6-Methylene-8 beta-alkyl-N-(cycloalkylmethyl)-3-hydroxy- or -methoxymorphinans.
Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Haplorhini; Humans; Mice; Morphinans; Morphine Dependence; Narcotic Antagonists; Rats; Reaction Time; Substance Withdrawal Syndrome | 1981 |
Analgesic narcotic antagonists. 4. 7-Methyl-N-(cycloalkylmethyl)-3-hydroxymorphinan-6-ones and -isomorphinan-6-ones.
Topics: Analgesics; Animals; Chemical Phenomena; Chemistry; Humans; Morphinans; Morphine Dependence; Narcotic Antagonists; Substance Withdrawal Syndrome | 1980 |
STUDYING THE PHYSICAL DEPENDENCE ON AND TOLERANCE TO THE ANTINOCICEPTIVE EFFECT OF RU-1205 SUBSTANCE.
Topics: Analgesics; Analgesics, Opioid; Animals; Animals, Outbred Strains; Benzimidazoles; Butorphanol; Drug Administration Schedule; Drug Tolerance; Male; Mice; Morphine; Morphine Dependence; Morpholines; Naloxone; Narcotic Antagonists; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 2016 |
7-nitroindazole, nitric oxide synthase inhibitor, attenuates physical dependence on butorphanol in rat.
Topics: Analgesics, Opioid; Animals; Brain; Butorphanol; Cell Count; Disease Models, Animal; Enzyme Inhibitors; Indazoles; Male; Narcotic Antagonists; Neurons; Nitric Oxide; Nitric Oxide Synthase Type I; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 2008 |
Acute withdrawal syndrome in a butorphanol-treated patient: an adverse combination of opioids.
Topics: Acute Disease; Analgesics, Opioid; Butorphanol; Humans; Intraoperative Complications; Male; Middle Aged; Substance Withdrawal Syndrome | 2008 |
Withdrawal from dependence upon butorphanol uniquely increases kappa(1)-opioid receptor binding in the rat brain.
Topics: Analgesics, Opioid; Animals; Binding Sites; Binding, Competitive; Brain; Butorphanol; Male; Morphine; Naloxone; Narcotic Antagonists; Neurons; Opioid-Related Disorders; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Up-Regulation | 2002 |
Focal kappa-opioid receptor-mediated dependence and withdrawal in the nucleus paragigantocellularis.
Topics: Animals; Basal Ganglia; Butorphanol; Diffusion; Electric Stimulation; Male; Microinjections; Morphine; Morphine Dependence; Naloxone; Naltrexone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Stereotaxic Techniques; Stereotyped Behavior; Substance Withdrawal Syndrome | 2002 |
The bindings of [3H]muscimol and [3H]flunitrazapam are elevated in discrete brain regions of butorphanol-withdrawal rats.
Topics: Animals; Autoradiography; Brain; Butorphanol; Flunitrazepam; Immunohistochemistry; Male; Muscimol; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tritium | 2002 |
Butorphanol dependence and withdrawal decrease hippocampal kappa 2-opioid receptor binding.
Topics: Animals; Butorphanol; Hippocampus; Male; Opioid-Related Disorders; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 2002 |
Enhanced binding of nor-binaltorphimine to kappa-opioid receptors in rats dependent on butorphanol.
Topics: Animals; Brain; Butorphanol; Dose-Response Relationship, Drug; Male; Naltrexone; Protein Binding; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Substance-Related Disorders | 2003 |
Changes in the brain kappa-opioid receptor levels of rats in withdrawal from physical dependence upon butorphanol.
Topics: Animals; Behavior, Animal; Brain; Butorphanol; Male; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Up-Regulation | 2003 |
Changes of the level of G protein alpha-subunit mRNA by tolerance to and withdrawal from butorphanol.
Topics: Animals; Base Sequence; Butorphanol; DNA Primers; Drug Tolerance; GTP-Binding Protein alpha Subunits; Male; Narcotics; Rats; Rats, Sprague-Dawley; RNA, Messenger; Substance Withdrawal Syndrome | 2003 |
Butorphanol dependence increases hippocampal kappa-opioid receptor gene expression.
Topics: Animals; Brain; Butorphanol; Disease Models, Animal; Down-Regulation; Gene Expression; Hippocampus; Injections, Intraventricular; Male; Narcotics; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; RNA, Messenger; Substance Withdrawal Syndrome; Up-Regulation | 2005 |
Increases in [(3)H]-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor binding and mRNA expression of AMPA-sensitive glutamate receptor A (GluR-A) subunits in rats withdrawn from butorphanol.
Topics: Analgesics, Opioid; Animals; Autoradiography; Brain; Butorphanol; Gene Expression Regulation; In Situ Hybridization; Injections, Intraventricular; Male; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, AMPA; RNA, Messenger; Substance Withdrawal Syndrome; Tritium | 2005 |
Self-administration of nalbuphine, butorphanol and pentazocine by morphine post-addict rats.
Topics: Animals; Butorphanol; Female; Humans; Morphinans; Morphine; Morphine Dependence; Nalbuphine; Pentazocine; Rats; Rats, Inbred Strains; Self Administration; Sleep, REM; Substance Withdrawal Syndrome | 1982 |
Ca2+ channel blocker, diltiazem, prevents physical dependence and the enhancement of protein kinase C activity by opioid infusion in rats.
Topics: Animals; Butorphanol; Calcium Channel Blockers; Diltiazem; Male; Medulla Oblongata; Morphine Dependence; Naloxone; Opioid-Related Disorders; Pons; Protein Kinase C; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1995 |
Increased locus coeruleus glutamate levels are associated with naloxone-precipitated withdrawal from butorphanol in the rat.
Topics: Animals; Butorphanol; Cerebral Ventricles; Glutamic Acid; Injections, Intraperitoneal; Injections, Intraventricular; Locus Coeruleus; Male; Microdialysis; Naloxone; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1995 |
Effects of morphine, naloxone, buprenorphine, butorphanol, haloperidol and imipramine on morphine withdrawal signs in cynomolgus monkeys.
Topics: Animals; Behavior, Animal; Buprenorphine; Butorphanol; Haloperidol; Imipramine; Macaca fascicularis; Male; Morphine; Morphine Dependence; Naloxone; Psychotropic Drugs; Substance Withdrawal Syndrome | 1994 |
Involvement of kappa-opioid receptors in opioid dependence/withdrawal: studies using butorphanol.
Topics: Animals; Butorphanol; Injections, Intraventricular; Male; Naloxone; Naltrexone; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Substance-Related Disorders | 1994 |
Effects of nor-binaltorphimine on butorphanol dependence.
Topics: Animals; Benzeneacetamides; Body Temperature; Body Weight; Butorphanol; Diarrhea; Down-Regulation; Drug Administration Schedule; Escape Reaction; Male; Naltrexone; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome; Substance-Related Disorders; Tremor | 1993 |
Butorphanol nasal spray for pain.
Topics: Administration, Intranasal; Butorphanol; Drug Tolerance; Humans; Pain; Substance Withdrawal Syndrome | 1993 |
Opioid antagonists and butorphanol dependence.
Topics: Animals; Behavior, Animal; Butorphanol; Indoles; Injections, Intraventricular; Male; Morphinans; Naltrexone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Substance Withdrawal Syndrome | 1993 |
Possible involvement of protein kinases in physical dependence on opioids: studies using protein kinase inhibitors, H-7 and H-8.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Behavior, Animal; Butorphanol; Cytosol; Enzyme Inhibitors; Isoquinolines; Male; Medulla Oblongata; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Piperazines; Pons; Protein Kinase C; Protein Kinase Inhibitors; Protein Kinases; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1995 |
Naloxone-precipitated changes in biogenic amines and their metabolites in various brain regions of butorphanol-dependent rats.
Topics: Animals; Biogenic Amines; Biogenic Monoamines; Brain Chemistry; Butorphanol; Injections, Intraperitoneal; Male; Morphine Dependence; Naloxone; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1996 |
Effects of diltiazem, a Ca2+ channel blocker, on naloxone-precipitated changes in dopamine and its metabolites in the brains of opioid-dependent rats.
Topics: Animals; Brain; Butorphanol; Calcium Channel Blockers; Cerebral Cortex; Corpus Striatum; Diltiazem; Dopamine; Male; Mesencephalon; Morphine; Naloxone; Narcotic Antagonists; Narcotics; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1996 |
Inhibitory effects of diltiazem, an L-type Ca2+ channel blocker, on naloxone-increased glutamate levels in the locus coeruleus of opioid-dependent rats.
Topics: Animals; Butorphanol; Calcium Channel Blockers; Diltiazem; Glutamic Acid; Locus Coeruleus; Male; Microdialysis; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome | 1996 |
Mu- and delta-opioid receptor antagonists precipitate similar withdrawal phenomena in butorphanol and morphine dependence.
Topics: Animals; Butorphanol; Drug Evaluation, Preclinical; Injections, Intraventricular; Locus Coeruleus; Male; Morphine; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, delta; Receptors, Opioid, mu; Somatostatin; Substance Withdrawal Syndrome | 1996 |
Precipitated kappa-opioid receptor agonist withdrawal increase glutamate in rat locus coeruleus.
Topics: Analgesics; Analysis of Variance; Animals; Aspartic Acid; Benzeneacetamides; Butorphanol; Glutamic Acid; Injections, Intraventricular; Locus Coeruleus; Male; Microdialysis; Naloxone; Narcotic Antagonists; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 1996 |
Increased release of excitatory amino acids in rat locus coeruleus in kappa-opioid agonist dependent rats precipitated by nor-binaltorphimine.
Topics: Animals; Benzeneacetamides; Butorphanol; Drug Evaluation, Preclinical; Excitatory Amino Acids; Locus Coeruleus; Male; Morphine; Naltrexone; Narcotic Antagonists; Narcotics; Pyrrolidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome; Substance-Related Disorders | 1997 |
Nor-binaltorphimine precipitates withdrawal and excitatory amino acid release in the locus ceruleus of butorphanol--but not morphine-dependent rats.
Topics: Animals; Butorphanol; Excitatory Amino Acids; Locus Coeruleus; Male; Microdialysis; Morphine Dependence; Naltrexone; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Opioid, kappa; Substance Withdrawal Syndrome | 1997 |
The role of glutamate in the locus coeruleus during opioid withdrawal and effects of H-7, a protein kinase inhibitor, on the action of glutamate in rats.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Butorphanol; Glutamic Acid; Infusions, Parenteral; Locus Coeruleus; Male; Microdialysis; Morphine Dependence; Motor Activity; Naloxone; Protein Kinase Inhibitors; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Substance-Related Disorders | 1998 |
Relative involvement of spinal opioid receptors in physical dependence on intrathecal butorphanol and morphine.
Topics: Animals; Butorphanol; Injections, Spinal; Male; Morphine; Morphine Dependence; Narcotic Antagonists; Narcotics; Opioid-Related Disorders; Rats; Rats, Sprague-Dawley; Receptors, Opioid; Spinal Cord; Substance Withdrawal Syndrome | 1998 |
Withdrawal from butorphanol dependence alters binding of [3H]phorbol dibutyrate to protein kinase C, but not of [3H]forskolin to adenylate cyclase.
Topics: Adenylyl Cyclases; Animals; Autoradiography; Brain; Brain Chemistry; Butorphanol; Carcinogens; Colforsin; Male; Narcotic Antagonists; Opioid-Related Disorders; Phorbol 12,13-Dibutyrate; Protein Kinase C; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tritium | 1999 |
Autoradiographic study of NMDA-displaceable [3H]glutamate and [3H]MK-801 binding during butorphanol withdrawal in the rat brain.
Topics: Animals; Autoradiography; Binding, Competitive; Brain Chemistry; Butorphanol; Dizocilpine Maleate; Excitatory Amino Acid Agonists; Excitatory Amino Acid Antagonists; Glutamic Acid; Injections, Intraventricular; Male; N-Methylaspartate; Narcotic Antagonists; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Tritium | 1999 |
Modulation of NMDA receptor subunit mRNA in butorphanol-tolerant and -withdrawing rats.
Topics: Animals; Autoradiography; Brain; Butorphanol; Dizocilpine Maleate; Drug Tolerance; In Situ Hybridization; Male; Narcotic Antagonists; Protein Isoforms; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Reference Values; RNA, Messenger; Substance Withdrawal Syndrome; Tissue Distribution | 2000 |
Effects of beta-funaltrexamine on butorphanol dependence.
Topics: Animals; Behavior, Animal; Body Temperature; Body Weight; Butorphanol; Dose-Response Relationship, Drug; Injections, Intraventricular; Male; Naloxone; Naltrexone; Narcotic Antagonists; Rats; Rats, Inbred Strains; Reinforcement Schedule; Substance Withdrawal Syndrome; Substance-Related Disorders | 1992 |
The physical dependence liability of butorphanol: a comparative study with morphine.
Topics: Animals; Behavior, Animal; Body Weight; Butorphanol; Injections, Intraventricular; Male; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome; Substance-Related Disorders | 1991 |
Butorphanol-precipitated withdrawal in opioid-dependent human volunteers.
Topics: Butorphanol; Heart Rate; Humans; Hydromorphone; Male; Methadone; Morphinans; Naloxone; Opioid-Related Disorders; Pupil; Respiration; Skin Temperature; Substance Withdrawal Syndrome; Surveys and Questionnaires | 1987 |
Butorphanol precipitates abstinence in morphine dependent rats.
Topics: Animals; Butorphanol; Dose-Response Relationship, Drug; Male; Morphinans; Morphine Dependence; Naloxone; Rats; Rats, Inbred Strains; Substance Withdrawal Syndrome | 1989 |
Acute abstinence syndrome after epidural injection of butorphanol.
Topics: Adult; Anesthesia, Epidural; Aspirin; Blood Pressure; Butorphanol; Caffeine; Cesarean Section; Codeine; Drug Combinations; Female; Humans; Morphinans; Nausea; Oxycodone; Phenacetin; Pregnancy; Reoperation; Substance Withdrawal Syndrome | 1985 |
Stadol dependence: another case.
Topics: Butorphanol; Humans; Male; Morphinans; Substance Withdrawal Syndrome; Substance-Related Disorders | 1985 |
Substitution and primary dependence studies in animals.
Topics: Animals; Behavior, Animal; Benzomorphans; Buprenorphine; Butorphanol; Codeine; Discrimination, Psychological; Humans; Macaca mulatta; Morphinans; Morphine; Morphine Dependence; Nalbuphine; Narcotic Antagonists; Pentazocine; Piperidines; Substance Withdrawal Syndrome | 1985 |