Page last updated: 2024-08-22

buthionine sulfoximine and Pregnancy

buthionine sulfoximine has been researched along with Pregnancy in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19905 (15.15)18.7374
1990's14 (42.42)18.2507
2000's12 (36.36)29.6817
2010's2 (6.06)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akhtar, F; Asmis, R; Catano, G; Kharbanda, K; Maffi, SK; Montalvo, M; Rouse, CA; Ullevig, SL1
Oshima, J; Reliene, R; Schiestl, RH; Yamamoto, ML1
Curnow, EC; Hayes, ES; Ryan, JP; Saunders, DM1
Cheong, J; JnoBaptiste, R; Kramer, BC; Mytilineou, C; Olanow, CW; Robakis, T; Yabut, JA2
Haddad, JJ; Lauterbach, R; Saadé, NE; Safieh-Garabedian, B1
Banerjee, U; Calvin, HI; Fu, SC; Guo, L; Li, W; Wu, K1
Castagné, V; Cuénod, M; Do, KQ1
Dixon, M; Hansen, JM; Harris, C1
Gardiner, CS; Gushansky, G; Mason, A; Matt, A; Salmen, JJ; Skufca, F1
Reliene, R; Schiestl, RH1
Hales, BF; Yan, J1
Andrews, JE; Ebron-McCoy, MT; Kavlock, RJ; Nichols, HP1
Contreras, R; Ott, S; Reyes, E; Robinson, B1
Aréchiga, CF; Ealy, AD; Hansen, PJ1
Gardiner, CS; Reed, DJ1
Maitra, I; Packer, L; Serbinova, E; Tritschler, HJ1
Harris, C; Hiranruengchok, R1
Ott, S; Reyes, E1
Aréchiga, CF; Hansen, PJ1
Perez-Polo, JR; Rassin, DK; Taglialatela, G1
Akazawa, S; Goto, S; Ishibashi, M; Izumino, K; Kondo, T; Nagataki, S; Sakamaki, H; Takino, H; Urata, Y; Yamaguchi, Y; Yamasaki, H1
Kang, UJ; Kowlessur, D; Lei, XG; Milstien, S; Nakamura, K; Wiatr, T; Wright, DA1
Heller, A; Kang, UJ; Nakamura, K; Won, L1
Bridges, RJ; Cotman, CW; Hatalski, CG; Koh, JY1
Brown, H; Hales, BF1
Bruno, M; Gamache, P; Hinson, JA; Khairallah, E; Klein, NW; Weeks, BS1
Deguchi, T; Mataki, Y; Naya, M; Takahira, H; Yasuda, M1
Cherian, MG; Gallant, KR1
Helston, LM; Wells, PG; Wong, M1
Hales, BF; Slott, VL2
Fantel, AG; Harris, C; Juchau, MR1

Other Studies

33 other study(ies) available for buthionine sulfoximine and Pregnancy

ArticleYear
Acute maternal oxidant exposure causes susceptibility of the fetal brain to inflammation and oxidative stress.
    Journal of neuroinflammation, 2017, Sep-30, Volume: 14, Issue:1

    Topics: Acetylcysteine; Animals; Antimetabolites; Brain; Buthionine Sulfoximine; Cytokines; Enzyme-Linked Immunosorbent Assay; Ethanol; Female; Fetus; Free Radical Scavengers; Glutathione; Inflammation; Male; Mice; Oxidative Stress; Pregnancy; Prenatal Exposure Delayed Effects; RNA, Messenger

2017
Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.
    Mutation research, 2008, Sep-26, Volume: 644, Issue:1-2

    Topics: 4-Nitroquinoline-1-oxide; Animals; Buthionine Sulfoximine; Disease Models, Animal; DNA; DNA Damage; DNA Repair; Exodeoxyribonucleases; Female; Genomic Instability; Glutathione; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Pigment Epithelium of Eye; Pregnancy; Recombination, Genetic; RecQ Helicases; Sequence Deletion; Werner Syndrome; Werner Syndrome Helicase

2008
Developmental potential of bovine oocytes following IVM in the presence of glutathione ethyl ester.
    Reproduction, fertility, and development, 2010, Volume: 22, Issue:4

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cattle; Embryonic Development; Female; Fertilization in Vitro; Glutathione; Male; Microscopy, Fluorescence; Oocytes; Pregnancy

2010
Lipopolysaccharide prevents cell death caused by glutathione depletion: possible mechanisms of protection.
    Neuroscience, 2002, Volume: 114, Issue:2

    Topics: Animals; Arachidonic Acid; Astrocytes; Brain; Buthionine Sulfoximine; Cell Death; Cells, Cultured; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Fetus; Free Radical Scavengers; Glutathione; Interleukin-1; Lipopolysaccharides; Microglia; Neuroglia; Neuroprotective Agents; Oxidative Stress; Parkinson Disease; Pregnancy; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Superoxides; Up-Regulation

2002
Inhibition of glutathione-related enzymes augments LPS-mediated cytokine biosynthesis: involvement of an IkappaB/NF-kappaB-sensitive pathway in the alveolar epithelium.
    International immunopharmacology, 2002, Volume: 2, Issue:11

    Topics: Animals; Antimetabolites; Blotting, Western; Buthionine Sulfoximine; Carmustine; Cytokines; Electrophoretic Mobility Shift Assay; Enzyme-Linked Immunosorbent Assay; Epithelial Cells; Female; Glutamate-Cysteine Ligase; Glutathione; Homeostasis; Lipopolysaccharides; NF-kappa B; Oxidation-Reduction; Pregnancy; Protein Disulfide Reductase (Glutathione); Pulmonary Alveoli; Rats; Rats, Sprague-Dawley; Signal Transduction; Sulfhydryl Compounds; Translocation, Genetic

2002
Induction of cortical cataracts in cultured mouse lenses with H-89, an inhibitor of protein kinase A.
    Current eye research, 2003, Volume: 27, Issue:5

    Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; alpha-Crystallin A Chain; Animals; Animals, Newborn; Buthionine Sulfoximine; Calcium; Cataract; Cyclic AMP-Dependent Protein Kinases; Electrophoresis, Gel, Two-Dimensional; Enzyme Inhibitors; Female; Isoquinolines; Lens Cortex, Crystalline; Male; Mice; Organ Culture Techniques; Phosphorylation; Potassium; Pregnancy; Protein Kinase C; Sodium; Spectrophotometry, Atomic; Sulfonamides

2003
Toxicity of glutathione depletion in mesencephalic cultures: a role for arachidonic acid and its lipoxygenase metabolites.
    The European journal of neuroscience, 2004, Volume: 19, Issue:2

    Topics: Animals; Arachidonic Acid; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Dose-Response Relationship, Drug; Female; Glutathione; Lipoxygenase; Mesencephalon; Pregnancy; Rats; Rats, Sprague-Dawley

2004
An animal model with relevance to schizophrenia: sex-dependent cognitive deficits in osteogenic disorder-Shionogi rats induced by glutathione synthesis and dopamine uptake inhibition during development.
    Neuroscience, 2004, Volume: 123, Issue:4

    Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain Chemistry; Buthionine Sulfoximine; Cognition Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Embryonic and Fetal Development; Enzyme Inhibitors; Exploratory Behavior; Female; Glutathione; Lipid Peroxidation; Male; Maze Learning; Medulla Oblongata; Motor Activity; Pharmacy and Therapeutics Committee; Piperazines; Pons; Pregnancy; Psychomotor Performance; Rats; Rats, Mutant Strains; Recognition, Psychology; Schizophrenia; Sex Characteristics; Time Factors

2004
Glutathione depletion modulates methanol, formaldehyde and formate toxicity in cultured rat conceptuses.
    Cell biology and toxicology, 2004, Volume: 20, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Cysteine; Embryo, Mammalian; Female; Formaldehyde; Formates; Glutathione; In Vitro Techniques; Male; Methanol; Pregnancy; Rats; Rats, Sprague-Dawley

2004
Role of glutathione in reproductive tract secretions on mouse preimplantation embryo development.
    Biology of reproduction, 2005, Volume: 73, Issue:2

    Topics: Animals; Antimetabolites; Blastocyst; Buthionine Sulfoximine; Embryonic Development; Female; Glutathione; Glutathione Disulfide; Male; Mice; Oocytes; Pregnancy; Uterus

2005
Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice.
    Carcinogenesis, 2006, Volume: 27, Issue:2

    Topics: Administration, Oral; Animals; Antimetabolites, Antineoplastic; Antioxidants; Buthionine Sulfoximine; Cell Transformation, Neoplastic; DNA Damage; Female; Gene Deletion; Glutamate-Cysteine Ligase; Glutathione; Mice; Mice, Inbred C57BL; Oxidative Stress; Pregnancy

2006
Depletion of glutathione induces 4-hydroxynonenal protein adducts and hydroxyurea teratogenicity in the organogenesis stage mouse embryo.
    The Journal of pharmacology and experimental therapeutics, 2006, Volume: 319, Issue:2

    Topics: Abnormalities, Drug-Induced; Aldehydes; Animals; Buthionine Sulfoximine; DNA; Embryo, Mammalian; Female; Glutathione; Hydroxyurea; Mice; Oxidative Stress; Pregnancy; Proto-Oncogene Proteins c-fos; Transcription Factor AP-1

2006
Profile of procarbazine-induced embryotoxicity in an embryo hepatocyte co-culture system and after in utero glutathione depletion.
    Teratogenesis, carcinogenesis, and mutagenesis, 1995, Volume: 15, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Antimetabolites; Biotransformation; Buthionine Sulfoximine; Cells, Cultured; Embryo, Mammalian; Embryonic and Fetal Development; Female; Glutathione; Ketones; Liver; Male; Methionine Sulfoximine; Organ Culture Techniques; Pregnancy; Procarbazine; Rats; Rats, Sprague-Dawley; Time Factors

1995
The effect of in utero administration of buthionine sulfoximine on rat development.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:4

    Topics: Abnormalities, Drug-Induced; Animals; Buthionine Sulfoximine; Embryonic and Fetal Development; Female; Glutamate-Cysteine Ligase; Glutathione; Maternal-Fetal Exchange; Methionine Sulfoximine; Pregnancy; Rats; Rats, Sprague-Dawley

1995
Evidence that glutathione is involved in thermotolerance of preimplantation murine embryos.
    Biology of reproduction, 1995, Volume: 52, Issue:6

    Topics: Animals; Blastocyst; Buthionine Sulfoximine; Embryonic Development; Female; Glutathione; Hot Temperature; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Morula; Pregnancy; Protein Biosynthesis; S-Adenosylmethionine

1995
Synthesis of glutathione in the preimplantation mouse embryo.
    Archives of biochemistry and biophysics, 1995, Apr-01, Volume: 318, Issue:1

    Topics: Animals; Antimetabolites; Blastocyst; Buthionine Sulfoximine; Culture Media; Cycloheximide; Cystine; Female; Glutathione; In Vitro Techniques; Maleates; Methionine; Methionine Sulfoximine; Mice; Pregnancy

1995
Stereospecific effects of R-lipoic acid on buthionine sulfoximine-induced cataract formation in newborn rats.
    Biochemical and biophysical research communications, 1996, Apr-16, Volume: 221, Issue:2

    Topics: Animals; Animals, Newborn; Ascorbic Acid; Buthionine Sulfoximine; Cataract; Female; Glutathione; Glutathione Disulfide; Lens, Crystalline; Methionine Sulfoximine; Pregnancy; Rats; Rats, Sprague-Dawley; Stereoisomerism; Thioctic Acid; Vitamin E

1996
Diamide-induced alterations of intracellular thiol status and the regulation of glucose metabolism in the developing rat conceptus in vitro.
    Teratology, 1995, Volume: 52, Issue:4

    Topics: Animals; Buthionine Sulfoximine; Diamide; Embryo, Mammalian; Embryonic and Fetal Development; Ethylmaleimide; Female; Glucose; Glucosephosphate Dehydrogenase; Glyceraldehyde-3-Phosphate Dehydrogenases; Lactic Acid; Organ Culture Techniques; Pentose Phosphate Pathway; Pregnancy; Rats; Rats, Sprague-Dawley; Sulfhydryl Reagents; Time Factors

1995
Effects of buthionine sulfoximine on the outcome of the in utero administration of alcohol on fetal development.
    Alcoholism, clinical and experimental research, 1996, Volume: 20, Issue:7

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cerebellum; Embryonic and Fetal Development; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Glutathione; Phosphopyruvate Hydratase; Pregnancy; Rats; Rats, Sprague-Dawley

1996
Response of preimplantation murine embryos to heat shock as modified by developmental stage and glutathione status.
    In vitro cellular & developmental biology. Animal, 1998, Volume: 34, Issue:8

    Topics: Adaptation, Physiological; Animals; Buthionine Sulfoximine; Culture Techniques; Embryonic Development; Enzyme Inhibitors; Female; Glutathione; Heat-Shock Response; Humans; Male; Mice; Mice, Inbred ICR; Pregnancy

1998
Induction of apoptosis in the CNS during development by the combination of hyperoxia and inhibition of glutathione synthesis.
    Free radical biology & medicine, 1998, Nov-15, Volume: 25, Issue:8

    Topics: Animals; Animals, Newborn; Apoptosis; Body Weight; Brain; Buthionine Sulfoximine; Cataract; Cerebellum; Corpus Striatum; Enzyme Inhibitors; Female; Glutathione; Hippocampus; Nerve Growth Factors; Oxygen; Pregnancy; Prosencephalon; Rats; Rats, Sprague-Dawley

1998
Significance of glutathione-dependent antioxidant system in diabetes-induced embryonic malformations.
    Diabetes, 1999, Volume: 48, Issue:5

    Topics: Animals; Antioxidants; Buthionine Sulfoximine; Congenital Abnormalities; Diabetes Mellitus, Experimental; Enzyme Inhibitors; Female; Fetal Growth Retardation; Fetus; Gestational Age; Glutamate-Cysteine Ligase; Glutathione; Insulin; Nervous System Malformations; Pregnancy; Pregnancy in Diabetics; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger

1999
Preferential resistance of dopaminergic neurons to the toxicity of glutathione depletion is independent of cellular glutathione peroxidase and is mediated by tetrahydrobiopterin.
    Journal of neurochemistry, 2000, Volume: 74, Issue:6

    Topics: Animals; Antioxidants; Biopterins; Buthionine Sulfoximine; Cell Survival; Dopamine; Enzyme Inhibitors; Female; Glutathione; Glutathione Peroxidase; Male; Mesencephalon; Mice; Mice, Inbred C57BL; Mice, Knockout; Neurons; Parkinson Disease; Pregnancy; Pteridines; Pterins; Pyrazoles; Rats; Rats, Sprague-Dawley; tert-Butylhydroperoxide

2000
Preferential resistance of dopaminergic neurons to glutathione depletion in a reconstituted nigrostriatal system.
    Brain research, 2000, Aug-11, Volume: 873, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Catecholamines; Cell Aggregation; Cells, Cultured; Dopamine; Female; Fetus; Glutathione; Mice; Mice, Inbred C57BL; Neostriatum; Nerve Degeneration; Neural Pathways; Neuroglia; Neurons; Parkinsonian Disorders; Pregnancy; Substantia Nigra; Time Factors

2000
Increased excitotoxic vulnerability of cortical cultures with reduced levels of glutathione.
    European journal of pharmacology, 1991, Jan-03, Volume: 192, Issue:1

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cerebral Cortex; Female; Glutamates; Glutamic Acid; Glutathione; L-Lactate Dehydrogenase; Methionine Sulfoximine; Mice; N-Methylaspartate; Pregnancy

1991
The effect of in vivo glutathione depletion with buthionine sulfoximine on rat embryo development.
    Teratology, 1991, Volume: 44, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Embryo, Mammalian; Embryonic and Fetal Development; Female; Gestational Age; Glutathione; Methionine Sulfoximine; Pregnancy; Pregnancy Outcome; Rats; Rats, Inbred Strains; Teratogens

1991
Acetaminophen toxicity to cultured rat embryos.
    Teratogenesis, carcinogenesis, and mutagenesis, 1990, Volume: 10, Issue:5

    Topics: Acetaminophen; Animals; Buthionine Sulfoximine; Culture Techniques; Female; Glutathione; Macaca mulatta; Maternal-Fetal Exchange; Methionine Sulfoximine; Pregnancy; Rats; Rats, Inbred Strains; Teratogens

1990
Effects of phorone and/or buthionine sulfoximine on teratogenicity of 5-fluorouracil in mice.
    Teratology, 1990, Volume: 41, Issue:3

    Topics: Animals; Buthionine Sulfoximine; Drug Interactions; Female; Fluorouracil; Glutathione; Ketones; Limb Deformities, Congenital; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Pregnancy; Teratogens

1990
Metabolic changes in glutathione and metallothionein in newborn rat liver.
    The Journal of pharmacology and experimental therapeutics, 1989, Volume: 249, Issue:2

    Topics: Alkynes; Animals; Animals, Newborn; Buthionine Sulfoximine; Cysteine; Female; gamma-Glutamyltransferase; Glutathione; Glycine; Liver; Metallothionein; Methionine Sulfoximine; Pargyline; Pregnancy; Rats; Zinc

1989
Enhancement of murine phenytoin teratogenicity by the gamma-glutamylcysteine synthetase inhibitor L-buthionine-(S,R)-sulfoximine and by the glutathione depletor diethyl maleate.
    Teratology, 1989, Volume: 40, Issue:2

    Topics: Administration, Oral; Analysis of Variance; Animals; Body Weight; Buthionine Sulfoximine; Cleft Palate; Female; Fetal Resorption; Fetal Viability; Glutathione; Infusions, Parenteral; Maleates; Methionine Sulfoximine; Mice; Phenytoin; Pregnancy; Teratogens

1989
Effect of glutathione depletion by buthionine sulfoximine on rat embryonic development in vitro.
    Biochemical pharmacology, 1987, Mar-01, Volume: 36, Issue:5

    Topics: Abnormalities, Drug-Induced; Animals; Buthionine Sulfoximine; Dose-Response Relationship, Drug; Embryo, Mammalian; Female; Glutamate-Ammonia Ligase; Glutathione; Methionine Sulfoximine; Organ Culture Techniques; Pregnancy; Rats; Rats, Inbred Strains

1987
Enhancement of the embryotoxicity of acrolein, but not phosphoramide mustard, by glutathione depletion in rat embryos in vitro.
    Biochemical pharmacology, 1987, Jun-15, Volume: 36, Issue:12

    Topics: Abnormalities, Drug-Induced; Acrolein; Aldehydes; Animals; Buthionine Sulfoximine; Drug Synergism; Embryo, Mammalian; Female; Fetal Death; Glutathione; Methionine Sulfoximine; Phosphoramide Mustards; Pregnancy; Rats; Rats, Inbred Strains

1987
Differential glutathione depletion by L-buthionine-S,R-sulfoximine in rat embryo versus visceral yolk sac in vivo and in vitro.
    Biochemical pharmacology, 1986, Dec-15, Volume: 35, Issue:24

    Topics: Animals; Buthionine Sulfoximine; Culture Techniques; Embryo, Mammalian; Female; Glutathione; Maternal-Fetal Exchange; Methionine Sulfoximine; Pregnancy; Rats; Rats, Inbred Strains; Time Factors; Yolk Sac

1986