buthionine sulfoximine has been researched along with Malignant Melanoma in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.90) | 18.7374 |
| 1990's | 15 (48.39) | 18.2507 |
| 2000's | 7 (22.58) | 29.6817 |
| 2010's | 4 (12.90) | 24.3611 |
| 2020's | 1 (3.23) | 2.80 |
| Authors | Studies |
|---|---|
| Buettner, GR; Fath, MA; Gnade, CM; Goswami, PC; Hedlund, DK; Kloepping, KC; Kraus, AS; Lim, TH; McCormick, ML; Pigge, FC; Schultz, MK; Seol, D; Spitz, DR; Wagner, BA | 1 |
| Campana, LG; De Mattei, M; De Terlizzi, F; Ongaro, A; Pellati, A; Rossi, CR | 1 |
| Fortunato, RS; Kajitani, GS; Menck, CF; Quinet, A; Rocha, CR | 1 |
| Barna, G; Magyar, K; Szende, B | 1 |
| Castellani, P; Ciriolo, MR; Delfino, L; Lucibello, M; Rubartelli, A; Venè, R | 1 |
| Doñate, F; Fruehauf, JP; Lee, K; Mazar, AP; Trapp, V | 1 |
| Buckmeier, JA; Cen, D; Gonzalez, RI; Kahlon, RS; Meyskens, FL; Tohidian, NB | 1 |
| Dubois, J; Duez, P; Ghanem, G; Kinnaert, E; Morandini, R; Van Houtte, P | 1 |
| Abdel-Wahab, O; Cheng, TY; Friedman, HS; Grubbs, EG; Michael Colvin, O; Pruitt, SK; Tyler, DS; Ueno, T | 1 |
| Cupissol, D; Cuq, P; Depeille, P; Evrard, A; Passagne, I; Vian, L | 1 |
| del Marmol, V; Ghanem, G; Huez, G; Lejeune, F; Libert, A; Sels, A; Solano, F | 1 |
| Bloomer, WD; Damodaran, KM; Prezioso, JA; Wang, N | 1 |
| Bolognia, JL; Osber, MP; Pawelek, JM; Sodi, SA | 1 |
| Benathan, M | 2 |
| Creaven, PJ; Pendyala, L; Perez, R; Weinstein, A; Zdanowicz, J | 1 |
| al-Bassam, M; Buzaid, AC; Dasgupta, C; Fruehauf, JP; Kyshtoobayeva, A; Milovanovic, T; Parker, RJ; Zonis, S | 2 |
| Arstrand, K; Dizdar, N; Kågedal, B; Kullman, A | 1 |
| Buckmeier, JA; McNulty, SE; Meyskens, FL; Tohidian, NB | 1 |
| Benathan, M; Furumura, M; Hearing, VJ; Kobayashi, N; Panizzon, RG; Virador, V | 1 |
| Dizdar, N; Kågedal, B; Kullman, A | 1 |
| Bäumer, AT; Hescheler, J; Ling, FC; Petrat, K; Sauer, H; Schallenberg, M; Wartenberg, M | 1 |
| Alvero-Jackson, H; Benathan, M; Frenk, E; Mooy, AM; Scaletta, C | 1 |
| Guenthner, TM; Jevtović-Todorović, V | 1 |
| FitzGerald, GB; Prezioso, JA; Wick, MM | 1 |
| Bloomer, WD; Epperly, MW; Prezioso, JA; Wang, N | 1 |
| Brötell, H; Karg, E; Rorsman, H; Rosengren, E | 1 |
| Favier, D; Kable, EP; Parsons, PG | 1 |
| Edgren, M; Ehrsson, H; Hansson, J; Nilsson, B; Ringborg, U | 1 |
| Guichard, M; Lespinasse, F; Malaise, EP | 1 |
31 other study(ies) available for buthionine sulfoximine and Malignant Melanoma
| Article | Year |
|---|---|
Triphenylphosphonium derivatives disrupt metabolism and inhibit melanoma growth in vivo when delivered via a thermosensitive hydrogel.
Topics: Animals; Auranofin; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Drug Synergism; Female; Humans; Hydrogels; Melanoma; Mice; Mitochondria; Organophosphorus Compounds; Oxidative Stress; Structure-Activity Relationship; Temperature; Xenograft Model Antitumor Assays | 2020 |
Enhancement of melphalan activity by buthionine sulfoximine and electroporation in melanoma cells.
Topics: Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Electroporation; Glutathione; Humans; Melanoma; Melphalan | 2015 |
NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Female; Glioma; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; NF-E2-Related Factor 2; Temozolomide; Xenograft Model Antitumor Assays | 2016 |
Cytoprotective effect of (-)-deprenyl, (-)desmethyl-deprenyl and (-)deprenyl-N-oxide on glutathione depleted A-2058 melanoma cells.
Topics: Amphetamines; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Cytoprotection; Drug Interactions; Flow Cytometry; Glutathione; Humans; Melanoma; Monoamine Oxidase Inhibitors; Radiation-Sensitizing Agents; Selegiline; Serum | 2010 |
The cystine/cysteine cycle and GSH are independent and crucial antioxidant systems in malignant melanoma cells and represent druggable targets.
Topics: Antioxidants; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Cell Survival; Cysteine; Cystine; Glutathione; Glycine; HMGB1 Protein; Humans; Immunohistochemistry; Melanoma; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Tumor Cells, Cultured | 2011 |
Redox-related antimelanoma activity of ATN-224.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Dacarbazine; Disulfiram; Drug Synergism; Enzyme Inhibitors; Glutathione; Humans; Melanins; Melanoma; Molybdenum; Oxidation-Reduction; Oxides; Reactive Oxygen Species; Superoxide Dismutase; Temozolomide | 2009 |
Disulfiram induces apoptosis in human melanoma cells: a redox-related process.
Topics: Antimetabolites, Antineoplastic; Apoptosis; Buthionine Sulfoximine; Cell Division; Disulfiram; Enzyme Inhibitors; Glutathione; Melanocytes; Melanoma; Membrane Potentials; Mitochondria; Neoplasm Metastasis; Oxidative Stress; Reactive Oxygen Species; Tumor Cells, Cultured | 2002 |
Cysteine but not glutathione modulates the radiosensitivity of human melanoma cells by affecting both survival and DNA damage.
Topics: Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Comet Assay; Cysteine; DNA Damage; Dose-Response Relationship, Radiation; Glutathione; Humans; Melanoma; Pigmentation; Radiation Tolerance; Radiation-Sensitizing Agents | 2004 |
Modulation of resistance to regional chemotherapy in the extremity melanoma model.
Topics: Animals; Buthionine Sulfoximine; Chemotherapy, Cancer, Regional Perfusion; Drug Resistance, Neoplasm; Female; Glutathione; Melanoma; Melphalan; Rats | 2004 |
O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Dacarbazine; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Inhibitory Concentration 50; Melanoma; Mitomycin; Nitrosourea Compounds; O(6)-Methylguanine-DNA Methyltransferase; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Temozolomide; Transfection | 2006 |
Glutathione depletion increases tyrosinase activity in human melanoma cells.
Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Glutathione; Humans; Melanins; Melanoma; Methionine Sulfoximine; Monophenol Monooxygenase; Sulfhydryl Compounds; Time Factors; Tumor Cells, Cultured; Tyrosine 3-Monooxygenase | 1993 |
Mechanism(s) regulating inhibition of thymidylate synthase and growth by gamma-L-glutaminyl-4-hydroxy-3-iodobenzene, a novel melanin precursor, in melanogenic melanoma cells.
Topics: Animals; Biotransformation; Buthionine Sulfoximine; Cell Division; Glutamine; Glutathione; GTP Phosphohydrolases; Humans; Melanins; Melanoma; Methionine Sulfoximine; Mice; Monophenol Monooxygenase; Oxidation-Reduction; Phenols; Protein Precursors; Tetrazolium Salts; Thiazoles; Thymidylate Synthase; Tumor Cells, Cultured | 1993 |
Enhancement of the depigmenting effect of hydroquinone by cystamine and buthionine sulfoximine.
Topics: Animals; Buthionine Sulfoximine; Cystamine; Drug Combinations; Drug Synergism; Enzyme Inhibitors; Guinea Pigs; Hair Color; Hydroquinones; Melanoma; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Monophenol Monooxygenase; Skin Pigmentation; Tumor Cells, Cultured | 1995 |
Modulation of 5-S-cysteinyldopa formation by tyrosinase activity and intracellular thiols in human melanoma cells.
Topics: Buthionine Sulfoximine; Catechols; Cell Line; Cysteine; Cysteinyldopa; Glutathione; Humans; Melanoma; Microscopy, Electron; Monophenol Monooxygenase; Tumor Cells, Cultured | 1996 |
Effect of glutathione depletion on the cytotoxicity of cisplatin and iproplatin in a human melanoma cell line.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Survival; Cisplatin; Glutathione; Humans; Melanoma; Organoplatinum Compounds; Tumor Cells, Cultured | 1997 |
Opposite regulation of tyrosinase and glutathione peroxidase by intracellular thiols in human melanoma cells.
Topics: Buthionine Sulfoximine; Carmustine; Cysteine; Cystine; Glutathione; Glutathione Peroxidase; Humans; Melanins; Melanoma; Monophenol Monooxygenase; Oxidative Stress; Sodium Selenite; Sulfhydryl Compounds; Tumor Cells, Cultured | 1997 |
Selective and synergistic activity of L-S,R-buthionine sulfoximine on malignant melanoma is accompanied by decreased expression of glutathione-S-transferase.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Breast Neoplasms; Buthionine Sulfoximine; Carmustine; Drug Synergism; Female; Glutathione; Glutathione Transferase; Humans; Melanins; Melanoma; Ovarian Neoplasms; Tumor Cells, Cultured | 1997 |
Effects on interstitial glutathione, cysteine and 5-S-cysteinyldopa of buthionine sulphoximine in human melanoma transplants.
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Drug Interactions; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Microdialysis; Neoplasm Transplantation; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines | 1997 |
Melanin content and downregulation of glutathione S-transferase contribute to the action of L-buthionine-S-sulfoximine on human melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Buthionine Sulfoximine; Carmustine; Down-Regulation; Drug Resistance; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione Transferase; Humans; Melanins; Melanoma; Melphalan; Ovarian Neoplasms; Tumor Cells, Cultured | 1998 |
Activation of nuclear factor-kappa B in human metastatic melanomacells and the effect of oxidative stress.
Topics: Buthionine Sulfoximine; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Hydrogen Peroxide; I-kappa B Proteins; Melanocytes; Melanoma; Neoplasm Metastasis; Neoplasm Proteins; NF-kappa B; NF-KappaB Inhibitor alpha; Oxidation-Reduction; Oxidative Stress; Protein Isoforms; Transcription Factor AP-1; Tumor Cells, Cultured | 1999 |
Co-regulation of melanin precursors and tyrosinase in human pigment cells: roles of cysteine and glutathione.
Topics: Buthionine Sulfoximine; Cells, Cultured; Cysteine; Cysteinyldopa; Dihydroxyphenylalanine; Glutathione; Humans; Infant, Newborn; Male; Melanins; Melanocytes; Melanoma; Melanosomes; Monophenol Monooxygenase; Neoplasm Proteins; Skin Neoplasms; Tumor Cells, Cultured; Tyrosine | 1999 |
Comparison of N-acetylcysteine and l-2-oxothiazolidine-4-carboxylate as cysteine deliverers and glutathione precursors in human malignant melanoma transplants in mice.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Cysteine; Cysteinyldopa; Enzyme Inhibitors; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Nude; Microdialysis; Neoplasm Transplantation; Protein Precursors; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Transplantation, Heterologous; Tumor Cells, Cultured | 2000 |
Down-regulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by reactive oxygen species.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Drug Resistance, Multiple; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kinetics; Liver Neoplasms; Male; MAP Kinase Signaling System; Melanoma; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein-Tyrosine Kinases; Reactive Oxygen Species; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
Relationship between melanogenesis, glutathione levels and melphalan toxicity in human melanoma cells.
Topics: Bucladesine; Buthionine Sulfoximine; Cell Differentiation; Cell Division; Cell Survival; Dose-Response Relationship, Drug; Eye Neoplasms; Glutathione; Glutathione Transferase; Humans; Kinetics; Melanins; Melanoma; Melphalan; Methionine Sulfoximine; Microscopy, Electron; Monophenol Monooxygenase; Neoplasm Staging; Skin Neoplasms; Tumor Cells, Cultured | 1992 |
Depletion of a discrete nuclear glutathione pool by oxidative stress, but not by buthionine sulfoximine. Correlation with enhanced alkylating agent cytotoxicity to human melanoma cells in vitro.
Topics: Buthionine Sulfoximine; Carmustine; Cell Division; Cell Nucleus; Cytosol; Doxorubicin; Drug Synergism; Glutathione; Glutathione Disulfide; Humans; Melanoma; Melphalan; Methionine Sulfoximine; Oxidation-Reduction; Tumor Cells, Cultured | 1992 |
Melanoma cytotoxicity of buthionine sulfoximine (BSO) alone and in combination with 3,4-dihydroxybenzylamine and melphalan.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Dopamine; Glutathione Peroxidase; Humans; Hydrogen Peroxide; Melanoma; Melanoma, Experimental; Melphalan; Methionine Sulfoximine; Mice; Tumor Cells, Cultured | 1992 |
Effects of tyrosinase activity on the cytotoxicity of 4-S-cysteaminylphenol and N-acetyl-4-S-cysteaminylphenol in melanoma cells.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cysteamine; Drug Synergism; Humans; Melanoma; Methionine Sulfoximine; Monophenol Monooxygenase; Phenols; Theophylline; Time Factors; Tumor Cells, Cultured | 1992 |
Modulation of glutathione level in cultured human melanoma cells.
Topics: Antimetabolites; Buthionine Sulfoximine; Cell Line; Cell Survival; Cysteine; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Tumor Cells, Cultured; Vitamin K | 1989 |
Sensitivity of human melanoma cells to L-dopa and DL-buthionine (S,R)-sulfoximine.
Topics: Buthionine Sulfoximine; Cell Cycle; Cell Survival; Glutathione; Humans; Levodopa; Melanoma; Methionine Sulfoximine; Tumor Cells, Cultured | 1989 |
Effect of D,L-buthionine-S,R-sulfoximine on cytotoxicity and DNA cross-linking induced by bifunctional DNA-reactive cytostatic drugs in human melanoma cells.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cell Survival; Cross-Linking Reagents; DNA; Drug Synergism; Glutathione; Humans; Melanoma; Melphalan; Methionine Sulfoximine; Tumor Cells, Cultured | 1988 |
Influence of buthionine sulfoximine and misonidazole on glutathione level and radiosensitivity of human tumor xenografts.
Topics: Adenocarcinoma; Animals; Buthionine Sulfoximine; Cell Line; Colonic Neoplasms; Female; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms; Radiation Tolerance; Transplantation, Heterologous | 1986 |