buthionine sulfoximine has been researched along with Lung Neoplasms in 47 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 11 (23.40) | 18.7374 |
1990's | 16 (34.04) | 18.2507 |
2000's | 11 (23.40) | 29.6817 |
2010's | 8 (17.02) | 24.3611 |
2020's | 1 (2.13) | 2.80 |
Authors | Studies |
---|---|
Cui, XY; Park, SH; Park, WH | 1 |
Falls, KC; Fath, MA; Klinger, AR; Rodman, SN; Ross, NL; Schoenfeld, JD; Sciegienka, SJ; Solst, SR; Spitz, DR | 1 |
Park, WH; You, BR | 2 |
Kaushik, G; Kaushik, T; Khanduja, KL; Pathak, CM; Ranawat, P; Sharma, SK; Yadav, SK | 1 |
Barhoumi, R; Burghardt, RC; Chapkin, RS; Mouneimne, Y | 1 |
Chen, C; Gu, S; Jiang, X; Zhang, Z | 1 |
Han, YH; Kim, SH; Kim, SZ; Park, WH | 2 |
Han, YH; Park, WH | 1 |
Han, YH; Kim, SH; Kim, SZ; Moon, HJ; Park, WH; You, BR | 1 |
Chen, J; Gao, AC; Li, Y; Liu, C; Liu, H; Wang, T; Wu, Z; Zhou, Q; Zhu, Y | 1 |
Järvinen, K; Kinnula, VL; Soini, Y | 1 |
Biswal, S; Kehrer, JP; Maxwell, T; Rangasamy, T | 1 |
Brisbay, SM; Cho, SH; Coppola, S; Fang, B; Ghibelli, L; Honda, T; Kagawa, S; McDonnell, TJ; Meyn, RE; Roth, JA; Spurgers, KB | 1 |
Foth, H; Glahn, F; Stehfest, E; Torky, A | 1 |
Astor, M; Biaglow, JE; Clark, EP; Epp, ER; Varnes, ME | 1 |
Biaglow, JE; Hall, EJ; Roizin-Towle, L; Varnes, ME | 1 |
Biaglow, JE; McPherson, S; Mitchell, JB; Russo, A | 1 |
Biaglow, JE; Clark, EP; Epp, ER; Varnes, ME | 1 |
Burt, ME; Hochwald, SN; Port, JL; Wang, HY | 1 |
Hwang, J; Lai, SL; Perng, RP; Whang-Peng, J | 1 |
Bagrij, T; Broxterman, HJ; Scheper, RJ; Twentyman, PR; Versantvoort, CH | 1 |
Baas, F; Beijnen, J; Borst, P; Dekker, H; Lankelma, J; Oude Elferink, RP; Paulusma, C; van Tellingen, O; Zaman, GJ | 1 |
Kang, YJ | 3 |
Alena, F; Gili, A; Iwashina, T; Jimbow, K | 1 |
Alexander, JM; Hatcher, EL; Kang, YJ | 1 |
Benderra, Z; Manfait, M; Morjani, H; Trussardi, A | 1 |
Guo, J; Hu, X; Pal, A; Singh, SV; Srivastava, SK; Xia, H | 1 |
de Vries, EE; Hooiveld, GJ; Jansen, PL; Krikken, I; Müller, M; Renes, J | 1 |
Cheng, L; de Boer, J; Dixon, K; Sonntag, DM | 1 |
Deloughery, TG; Hasler, BP; Muldoon, LL; Neuwelt, EA; Pagel, MA | 1 |
Lafleur, MV; Lankelma, J; Mans, DR; Pinedo, HM; Retèl, J; Schuurhuis, GJ; Treskes, M | 1 |
de Vries, EG; Meijer, C; Mulder, NH; Peters, WH; Timmer-Bosscha, H | 1 |
Emery, D; Enger, MD; Kang, YJ | 1 |
al-Kabban, M; Reglinski, J; Stewart, MJ; Watson, ID | 1 |
Enger, MD; Kang, YJ | 3 |
de Vries, EG; Hospers, GA; Meijer, C; Mulder, NH; Uges, DR | 1 |
DeGraff, W; Friedman, N; Mitchell, JB; Russo, A | 1 |
Clapper, JA; Enger, MD; Kang, YJ | 1 |
Konings, AW; Lemstra, W; Malingré, TM; Woerdenbag, HJ | 1 |
Abe, M; Komuro, C; Nishidai, T; Ono, K; Shibamoto, Y; Shrieve, DC; Takahashi, M; Tsutsui, K | 1 |
Brodie, AE; Reed, DJ | 1 |
47 other study(ies) available for buthionine sulfoximine and Lung Neoplasms
Article | Year |
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Anti-Cancer Effects of Auranofin in Human Lung Cancer Cells by Increasing Intracellular ROS Levels and Depleting GSH Levels.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Auranofin; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Reactive Oxygen Species | 2022 |
D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H
Topics: Antineoplastic Combined Chemotherapy Protocols; Auranofin; Breast Neoplasms; Buthionine Sulfoximine; Carboplatin; Catalase; Cell Line, Tumor; Chelating Agents; Copper; Epithelial Cells; Female; Humans; Hydrogen Peroxide; Lung Neoplasms; Oxidative Stress; Penicillamine; Radiation; Thioredoxin-Disulfide Reductase | 2017 |
Suberoylanilide hydroxamic acid induces thioredoxin1-mediated apoptosis in lung cancer cells via up-regulation of miR-129-5p.
Topics: 3' Untranslated Regions; A549 Cells; Acetylcysteine; Apoptosis; Blotting, Western; Buthionine Sulfoximine; Cell Line; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutathione; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; MAP Kinase Kinase Kinase 5; MAP Kinase Signaling System; MicroRNAs; Reactive Oxygen Species; Thioredoxins; Up-Regulation; Vorinostat | 2017 |
Curcumin sensitizes lung adenocarcinoma cells to apoptosis via intracellular redox status mediated pathway.
Topics: Acetylcysteine; Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Buthionine Sulfoximine; Caspase 3; Cell Line, Tumor; Curcumin; Drug Screening Assays, Antitumor; Enzyme Activation; Enzyme Induction; Glutamate-Cysteine Ligase; Glutathione; Humans; Lipid Peroxidation; Lung Neoplasms; MAP Kinase Signaling System; Oxidants; Oxidation-Reduction; Phosphorylation; Protein Processing, Post-Translational; Reactive Oxygen Species; RNA, Messenger; RNA, Neoplasm; Superoxides | 2012 |
Effects of fatty acids on benzo[a]pyrene uptake and metabolism in human lung adenocarcinoma A549 cells.
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Benzo(a)pyrene; Buthionine Sulfoximine; Cattle; Cell Line, Tumor; Cytochrome P-450 CYP1A1; DNA Adducts; Docosahexaenoic Acids; Fatty Acids; Glutathione; Humans; Lung Neoplasms; Photons; Serum Albumin, Bovine | 2014 |
[Study on the resveratrol and arsenic trioxide combination induced apoptosis and its mechanism on lung adenocarcinoma cells].
Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Caspase 3; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxides; Resveratrol; Stilbenes; Tumor Cells, Cultured | 2016 |
Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2(*-) generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells.
Topics: Adenocarcinoma; Apoptosis; Buthionine Sulfoximine; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line, Tumor; Dithiothreitol; Free Radical Scavengers; Glutathione; Humans; Lung Neoplasms; Superoxides | 2009 |
Induction of apoptosis in arsenic trioxide-treated lung cancer A549 cells by buthionine sulfoximine.
Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Cycle; Cell Membrane; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Oxides; Reactive Oxygen Species; Tumor Cells, Cultured | 2008 |
The effects of N-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione.
Topics: Acetylcysteine; Adenocarcinoma; Amitrole; Antimycin A; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Reactive Oxygen Species | 2009 |
The effects of N-acetyl cysteine on the MG132 proteasome inhibitor-treated lung cancer cells in relation to cell growth, reactive oxygen species and glutathione.
Topics: Acetylcysteine; Apoptosis; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Glutathione; Humans; Leupeptins; Lung Neoplasms; Membrane Potential, Mitochondrial; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reactive Oxygen Species | 2010 |
Gallic acid-induced lung cancer cell death is related to glutathione depletion as well as reactive oxygen species increase.
Topics: Acetylcysteine; Antineoplastic Agents; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Cell Proliferation; Gallic Acid; Glutathione; Humans; Lung Neoplasms; Oxidative Stress; Reactive Oxygen Species | 2010 |
Intracellular glutathione content influences the sensitivity of lung cancer cell lines to methylseleninic acid.
Topics: Acetylcysteine; Apoptosis; Buthionine Sulfoximine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Glutathione; Glutathione Transferase; Humans; Lung Neoplasms; Microscopy, Fluorescence; Organoselenium Compounds; Oxidative Stress; Reactive Oxygen Species | 2012 |
gamma-Glutamylcysteine synthetase in lung cancer. Effect on cell viability.
Topics: Biopsy; Bronchi; Buthionine Sulfoximine; Cell Survival; Enzyme Inhibitors; Epithelium; Glutamate-Cysteine Ligase; Immunoenzyme Techniques; Lung Neoplasms; Paraffin Embedding; Tumor Cells, Cultured | 2003 |
Modulation of benzo[a]pyrene-induced p53 DNA activity by acrolein.
Topics: Acrolein; Adenocarcinoma; Antimetabolites, Antineoplastic; Benzo(a)pyrene; Blotting, Western; Buthionine Sulfoximine; DNA, Neoplasm; Electrophoretic Mobility Shift Assay; Glutathione; Humans; Luciferases; Lung Neoplasms; Precipitin Tests; Promoter Regions, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53 | 2003 |
GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells.
Topics: Adenoviridae; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Biological Assay; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Caspase 3; Caspases; Cell Line, Tumor; Combined Modality Therapy; Cytochromes c; Deoxyribonucleases; Gene Transfer Techniques; Genes, bcl-2; Genetic Vectors; Glutathione; Humans; Lung Neoplasms; Mitochondria; Oxidation-Reduction; Poly-ADP-Ribose Binding Proteins; Proto-Oncogene Proteins c-bcl-2 | 2004 |
Non-destructive micromethod for MRP1 functional assay in human lung tumor cells.
Topics: Acetylcysteine; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Buthionine Sulfoximine; Cell Culture Techniques; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Fluorometry; Glutathione; Humans; Immunohistochemistry; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Sensitivity and Specificity; Verapamil | 2006 |
Factors involved in depletion of glutathione from A549 human lung carcinoma cells: implications for radiotherapy.
Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Radiation-Sensitizing Agents; Time Factors | 1984 |
Depletion of intracellular GSH and NPSH by buthionine sulfoximine and diethyl maleate: factors that influence enhancement of aerobic radiation response.
Topics: Aerobiosis; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Time Factors | 1984 |
Cellular glutathione depletion by diethyl maleate or buthionine sulfoximine: no effect of glutathione depletion on the oxygen enhancement ratio.
Topics: Animals; Buthionine Sulfoximine; Carcinoma; Cell Line; Cells, Cultured; Cricetinae; Dose-Response Relationship, Radiation; Glutathione; Humans; Hypoxia; Lung; Lung Neoplasms; Maleates; Methionine Sulfoximine; Oxygen Consumption; Radiation-Sensitizing Agents; Time Factors | 1983 |
The role of thiols in cellular response to radiation and drugs.
Topics: Animals; Azo Compounds; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; Cricetinae; Diamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Ovary; Oxygen; Radiation-Sensitizing Agents; Sulfhydryl Compounds | 1983 |
Buthionine sulfoximine pretreatment potentiates the effect of isolated lung perfusion with doxorubicin.
Topics: Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Chemotherapy, Cancer, Regional Perfusion; Doxorubicin; Drug Synergism; Glutathione; Hydroxyethyl Starch Derivatives; Liver; Lung Neoplasms; Male; Methionine Sulfoximine; Rats; Rats, Inbred F344; Sarcoma, Experimental | 1995 |
Modulation of cisplatin resistance in acquired-resistant nonsmall cell lung cancer cells.
Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA Repair; DNA, Neoplasm; Drug Interactions; Drug Resistance; Drug Screening Assays, Antitumor; Glutathione; Glutathione Transferase; Humans; Intracellular Fluid; Lung Neoplasms; Methionine Sulfoximine; Pentoxifylline; Tumor Cells, Cultured | 1995 |
Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein.
Topics: Biological Transport; Buthionine Sulfoximine; Daunorubicin; Drug Resistance, Multiple; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Rhodamine 123; Rhodamines; RNA, Messenger; Tumor Cells, Cultured | 1995 |
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenites; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cell Division; Cysteine; Drug Resistance, Multiple; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Multidrug Resistance-Associated Proteins; Recombinant Proteins; Transfection; Tumor Cells, Cultured | 1995 |
Buthionine sulfoximine spares intracellular glutamate: a possible mechanism for cell growth stimulation.
Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Division; Cell Line; Chromatography, High Pressure Liquid; DNA Replication; Glutamates; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Thymidine; Tumor Cells, Cultured | 1993 |
Exogenous glutathione attenuates the antiproliferative effect of buthionine sulfoximine.
Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinoma; Cell Division; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured | 1994 |
Selective in vivo accumulation of N-acetyl-4-S-cysteaminylphenol in B16F10 murine melanoma and enhancement of its in vitro and in vivo antimelanoma effect by combination of buthionine sulfoximine.
Topics: Animals; Autoradiography; Buthionine Sulfoximine; Cysteamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Glutathione; Lung Neoplasms; Melanoma, Experimental; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Phenols | 1994 |
Buthionine sulfoximine enhances glutathione-but attenuates glutamate-stimulated cell proliferation.
Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinoma; Cell Division; Culture Media; Enzyme Inhibitors; Glutamic Acid; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured | 1995 |
Decreased sensitivity to adriamycin in cadmium-resistant human lung carcinoma A549 cells.
Topics: Antibiotics, Antineoplastic; Buthionine Sulfoximine; Cadmium; Carcinogens, Environmental; Doxorubicin; Drug Resistance; Glutathione; Humans; Lung Neoplasms; Tumor Cells, Cultured | 1997 |
Characterization of H+-ATPase-dependent activity of multidrug resistance-associated protein in homoharringtonine-resistant human leukemic K562 cells.
Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Cell Survival; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Harringtonines; Homoharringtonine; Humans; K562 Cells; Kinetics; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Proton-Translocating ATPases; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured | 1998 |
Potentiation of benzo[a]pyrene-induced pulmonary and forestomach tumorigenesis in mice by D,L-buthionine-S,R-sulfoximine-mediated tissue glutathione depletion.
Topics: Animals; Antimetabolites; Benzo(a)pyrene; Buthionine Sulfoximine; Carcinogens; Drug Synergism; Female; Glutathione; Lung Neoplasms; Mice; Stomach Neoplasms | 2000 |
Multidrug resistance protein MRP1 protects against the toxicity of the major lipid peroxidation product 4-hydroxynonenal.
Topics: Adenosine Triphosphate; Aldehydes; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Buthionine Sulfoximine; Carcinoma, Small Cell; Cell Line; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Immunoblotting; Insecta; Kinetics; Leukotriene Antagonists; Lipid Peroxidation; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Oxidative Stress; Propionates; Quinolines; Recombinant Proteins; Time Factors; Tumor Cells, Cultured | 2000 |
Chromium(VI)-induced mutagenesis in the lungs of big blue transgenic mice.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Carcinogens; DNA; Dose-Response Relationship, Drug; Female; Glutathione; Instillation, Drug; Kidney; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis; Mutagens; Mutation; Potassium Dichromate; Trachea | 2000 |
Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model.
Topics: Acetylcysteine; Animals; Antimetabolites; Antineoplastic Agents, Alkylating; Aorta, Thoracic; Blood-Brain Barrier; Bone Marrow Diseases; Brain; Brain Neoplasms; Buthionine Sulfoximine; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione; Infusions, Intra-Arterial; Lung Neoplasms; Rats; Rats, Long-Evans; Tissue Distribution; Xenograft Model Antitumor Assays | 2001 |
Modulation by D,L-buthionine-S,R-sulphoximine of etoposide cytotoxicity on human non-small cell lung, ovarian and breast carcinoma cell lines.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cisplatin; Doxorubicin; Drug Synergism; Etoposide; Female; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil | 1992 |
Combined in vitro modulation of adriamycin resistance.
Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Carcinoma, Small Cell; Cell Line; Cell Survival; Doxorubicin; Drug Resistance; Glutathione; Humans; Lung Neoplasms; Membrane Glycoproteins; Methionine Sulfoximine; Neoplasm Proteins; Pleural Effusion | 1991 |
Buthionine sulfoximine induced growth inhibition in human lung carcinoma cells does not correlate with glutathione depletion.
Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; DNA, Neoplasm; Flow Cytometry; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Microscopy, Electron; Tumor Cells, Cultured | 1991 |
The effect of doxorubicin on the glutathione content and viability of cultured human lung cancer cell lines A549 and GLC4 210.
Topics: Adenocarcinoma; Buthionine Sulfoximine; Carcinoma, Small Cell; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Doxorubicin; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured | 1990 |
Glutathione content and growth in A549 human lung carcinoma cells.
Topics: Antimetabolites; Buthionine Sulfoximine; Cell Division; Cell Line; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Time Factors; Tumor Cells, Cultured | 1990 |
The role of glutathione in resistance to cisplatin in a human small cell lung cancer cell line.
Topics: Antimetabolites; Buthionine Sulfoximine; Carcinoma; Cell Line; Cell Nucleus; Cell Survival; Cisplatin; DNA; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Neoplasm Proteins | 1990 |
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
Topics: Antineoplastic Agents; Bleomycin; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cisplatin; Glutathione; Humans; Lung; Lung Neoplasms; Melphalan; Methionine Sulfoximine; Neoplasms; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin | 1986 |
Enhanced cadmium cytotoxicity in A549 cells with reduced glutathione levels is due to neither enhanced cadmium accumulation nor reduced metallothionein synthesis.
Topics: Buthionine Sulfoximine; Cadmium; Glutathione; Humans; Lung Neoplasms; Maleates; Metallothionein; Methionine Sulfoximine; Sulfur Radioisotopes; Tumor Cells, Cultured | 1989 |
Enhanced cytostatic activity of the sesquiterpene lactone eupatoriopicrin by glutathione depletion.
Topics: Animals; Antimetabolites; Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Female; Glutathione; Lung Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Sesquiterpenes; Tumor Cells, Cultured | 1989 |
Glutathione is involved in the early cadmium cytotoxic response in human lung carcinoma cells.
Topics: Buthionine Sulfoximine; Cadmium; Drug Interactions; Glutathione; Humans; In Vitro Techniques; Lung Neoplasms; Methionine Sulfoximine | 1988 |
Effect of cellular glutathione depletion on cadmium-induced cytotoxicity in human lung carcinoma cells.
Topics: Buthionine Sulfoximine; Cadmium; Cell Survival; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Tumor Cells, Cultured | 1987 |
Combined effect of buthionine sulfoximine and cyclophosphamide upon murine tumours and bone marrow.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Buthionine Sulfoximine; Cell Survival; Colony-Forming Units Assay; Cyclophosphamide; Cysteine; Glutathione; Lung Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Inbred C3H | 1986 |
Buthionine sulfoximine inhibition of cystine uptake and glutathione biosynthesis in human lung carcinoma cells.
Topics: Buthionine Sulfoximine; Cell Line; Cysteine; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Sulfur Radioisotopes | 1985 |