Page last updated: 2024-08-22

buthionine sulfoximine and Lung Neoplasms

buthionine sulfoximine has been researched along with Lung Neoplasms in 47 studies

Research

Studies (47)

TimeframeStudies, this research(%)All Research%
pre-199011 (23.40)18.7374
1990's16 (34.04)18.2507
2000's11 (23.40)29.6817
2010's8 (17.02)24.3611
2020's1 (2.13)2.80

Authors

AuthorsStudies
Cui, XY; Park, SH; Park, WH1
Falls, KC; Fath, MA; Klinger, AR; Rodman, SN; Ross, NL; Schoenfeld, JD; Sciegienka, SJ; Solst, SR; Spitz, DR1
Park, WH; You, BR2
Kaushik, G; Kaushik, T; Khanduja, KL; Pathak, CM; Ranawat, P; Sharma, SK; Yadav, SK1
Barhoumi, R; Burghardt, RC; Chapkin, RS; Mouneimne, Y1
Chen, C; Gu, S; Jiang, X; Zhang, Z1
Han, YH; Kim, SH; Kim, SZ; Park, WH2
Han, YH; Park, WH1
Han, YH; Kim, SH; Kim, SZ; Moon, HJ; Park, WH; You, BR1
Chen, J; Gao, AC; Li, Y; Liu, C; Liu, H; Wang, T; Wu, Z; Zhou, Q; Zhu, Y1
Järvinen, K; Kinnula, VL; Soini, Y1
Biswal, S; Kehrer, JP; Maxwell, T; Rangasamy, T1
Brisbay, SM; Cho, SH; Coppola, S; Fang, B; Ghibelli, L; Honda, T; Kagawa, S; McDonnell, TJ; Meyn, RE; Roth, JA; Spurgers, KB1
Foth, H; Glahn, F; Stehfest, E; Torky, A1
Astor, M; Biaglow, JE; Clark, EP; Epp, ER; Varnes, ME1
Biaglow, JE; Hall, EJ; Roizin-Towle, L; Varnes, ME1
Biaglow, JE; McPherson, S; Mitchell, JB; Russo, A1
Biaglow, JE; Clark, EP; Epp, ER; Varnes, ME1
Burt, ME; Hochwald, SN; Port, JL; Wang, HY1
Hwang, J; Lai, SL; Perng, RP; Whang-Peng, J1
Bagrij, T; Broxterman, HJ; Scheper, RJ; Twentyman, PR; Versantvoort, CH1
Baas, F; Beijnen, J; Borst, P; Dekker, H; Lankelma, J; Oude Elferink, RP; Paulusma, C; van Tellingen, O; Zaman, GJ1
Kang, YJ3
Alena, F; Gili, A; Iwashina, T; Jimbow, K1
Alexander, JM; Hatcher, EL; Kang, YJ1
Benderra, Z; Manfait, M; Morjani, H; Trussardi, A1
Guo, J; Hu, X; Pal, A; Singh, SV; Srivastava, SK; Xia, H1
de Vries, EE; Hooiveld, GJ; Jansen, PL; Krikken, I; Müller, M; Renes, J1
Cheng, L; de Boer, J; Dixon, K; Sonntag, DM1
Deloughery, TG; Hasler, BP; Muldoon, LL; Neuwelt, EA; Pagel, MA1
Lafleur, MV; Lankelma, J; Mans, DR; Pinedo, HM; Retèl, J; Schuurhuis, GJ; Treskes, M1
de Vries, EG; Meijer, C; Mulder, NH; Peters, WH; Timmer-Bosscha, H1
Emery, D; Enger, MD; Kang, YJ1
al-Kabban, M; Reglinski, J; Stewart, MJ; Watson, ID1
Enger, MD; Kang, YJ3
de Vries, EG; Hospers, GA; Meijer, C; Mulder, NH; Uges, DR1
DeGraff, W; Friedman, N; Mitchell, JB; Russo, A1
Clapper, JA; Enger, MD; Kang, YJ1
Konings, AW; Lemstra, W; Malingré, TM; Woerdenbag, HJ1
Abe, M; Komuro, C; Nishidai, T; Ono, K; Shibamoto, Y; Shrieve, DC; Takahashi, M; Tsutsui, K1
Brodie, AE; Reed, DJ1

Other Studies

47 other study(ies) available for buthionine sulfoximine and Lung Neoplasms

ArticleYear
Anti-Cancer Effects of Auranofin in Human Lung Cancer Cells by Increasing Intracellular ROS Levels and Depleting GSH Levels.
    Molecules (Basel, Switzerland), 2022, Aug-15, Volume: 27, Issue:16

    Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Auranofin; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Reactive Oxygen Species

2022
D-penicillamine combined with inhibitors of hydroperoxide metabolism enhances lung and breast cancer cell responses to radiation and carboplatin via H
    Free radical biology & medicine, 2017, Volume: 108

    Topics: Antineoplastic Combined Chemotherapy Protocols; Auranofin; Breast Neoplasms; Buthionine Sulfoximine; Carboplatin; Catalase; Cell Line, Tumor; Chelating Agents; Copper; Epithelial Cells; Female; Humans; Hydrogen Peroxide; Lung Neoplasms; Oxidative Stress; Penicillamine; Radiation; Thioredoxin-Disulfide Reductase

2017
Suberoylanilide hydroxamic acid induces thioredoxin1-mediated apoptosis in lung cancer cells via up-regulation of miR-129-5p.
    Molecular carcinogenesis, 2017, Volume: 56, Issue:12

    Topics: 3' Untranslated Regions; A549 Cells; Acetylcysteine; Apoptosis; Blotting, Western; Buthionine Sulfoximine; Cell Line; Cell Line, Tumor; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Glutathione; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Lung Neoplasms; MAP Kinase Kinase Kinase 5; MAP Kinase Signaling System; MicroRNAs; Reactive Oxygen Species; Thioredoxins; Up-Regulation; Vorinostat

2017
Curcumin sensitizes lung adenocarcinoma cells to apoptosis via intracellular redox status mediated pathway.
    Indian journal of experimental biology, 2012, Volume: 50, Issue:12

    Topics: Acetylcysteine; Adenocarcinoma; Antineoplastic Agents, Phytogenic; Antioxidants; Apoptosis; Buthionine Sulfoximine; Caspase 3; Cell Line, Tumor; Curcumin; Drug Screening Assays, Antitumor; Enzyme Activation; Enzyme Induction; Glutamate-Cysteine Ligase; Glutathione; Humans; Lipid Peroxidation; Lung Neoplasms; MAP Kinase Signaling System; Oxidants; Oxidation-Reduction; Phosphorylation; Protein Processing, Post-Translational; Reactive Oxygen Species; RNA, Messenger; RNA, Neoplasm; Superoxides

2012
Effects of fatty acids on benzo[a]pyrene uptake and metabolism in human lung adenocarcinoma A549 cells.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Benzo(a)pyrene; Buthionine Sulfoximine; Cattle; Cell Line, Tumor; Cytochrome P-450 CYP1A1; DNA Adducts; Docosahexaenoic Acids; Fatty Acids; Glutathione; Humans; Lung Neoplasms; Photons; Serum Albumin, Bovine

2014
[Study on the resveratrol and arsenic trioxide combination induced apoptosis and its mechanism on lung adenocarcinoma cells].
    Wei sheng yan jiu = Journal of hygiene research, 2016, Volume: 45, Issue:1

    Topics: Adenocarcinoma; Adenocarcinoma of Lung; Anticarcinogenic Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Caspase 3; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Mitochondria; Oxidation-Reduction; Oxides; Resveratrol; Stilbenes; Tumor Cells, Cultured

2016
Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2(*-) generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells.
    Lung cancer (Amsterdam, Netherlands), 2009, Volume: 63, Issue:2

    Topics: Adenocarcinoma; Apoptosis; Buthionine Sulfoximine; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line, Tumor; Dithiothreitol; Free Radical Scavengers; Glutathione; Humans; Lung Neoplasms; Superoxides

2009
Induction of apoptosis in arsenic trioxide-treated lung cancer A549 cells by buthionine sulfoximine.
    Molecules and cells, 2008, Aug-31, Volume: 26, Issue:2

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Cycle; Cell Membrane; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Oxides; Reactive Oxygen Species; Tumor Cells, Cultured

2008
The effects of N-acetyl cysteine, buthionine sulfoximine, diethyldithiocarbamate or 3-amino-1,2,4-triazole on antimycin A-treated Calu-6 lung cells in relation to cell growth, reactive oxygen species and glutathione.
    Oncology reports, 2009, Volume: 22, Issue:2

    Topics: Acetylcysteine; Adenocarcinoma; Amitrole; Antimycin A; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Glutathione; Humans; Lung Neoplasms; Membrane Potential, Mitochondrial; Reactive Oxygen Species

2009
The effects of N-acetyl cysteine on the MG132 proteasome inhibitor-treated lung cancer cells in relation to cell growth, reactive oxygen species and glutathione.
    International journal of molecular medicine, 2010, Volume: 25, Issue:4

    Topics: Acetylcysteine; Apoptosis; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Ditiocarb; Glutathione; Humans; Leupeptins; Lung Neoplasms; Membrane Potential, Mitochondrial; Proteasome Endopeptidase Complex; Proteasome Inhibitors; Reactive Oxygen Species

2010
Gallic acid-induced lung cancer cell death is related to glutathione depletion as well as reactive oxygen species increase.
    Toxicology in vitro : an international journal published in association with BIBRA, 2010, Volume: 24, Issue:5

    Topics: Acetylcysteine; Antineoplastic Agents; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Cell Proliferation; Gallic Acid; Glutathione; Humans; Lung Neoplasms; Oxidative Stress; Reactive Oxygen Species

2010
Intracellular glutathione content influences the sensitivity of lung cancer cell lines to methylseleninic acid.
    Molecular carcinogenesis, 2012, Volume: 51, Issue:4

    Topics: Acetylcysteine; Apoptosis; Buthionine Sulfoximine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Flow Cytometry; Glutathione; Glutathione Transferase; Humans; Lung Neoplasms; Microscopy, Fluorescence; Organoselenium Compounds; Oxidative Stress; Reactive Oxygen Species

2012
gamma-Glutamylcysteine synthetase in lung cancer. Effect on cell viability.
    Methods in molecular medicine, 2003, Volume: 74

    Topics: Biopsy; Bronchi; Buthionine Sulfoximine; Cell Survival; Enzyme Inhibitors; Epithelium; Glutamate-Cysteine Ligase; Immunoenzyme Techniques; Lung Neoplasms; Paraffin Embedding; Tumor Cells, Cultured

2003
Modulation of benzo[a]pyrene-induced p53 DNA activity by acrolein.
    Carcinogenesis, 2003, Volume: 24, Issue:8

    Topics: Acrolein; Adenocarcinoma; Antimetabolites, Antineoplastic; Benzo(a)pyrene; Blotting, Western; Buthionine Sulfoximine; DNA, Neoplasm; Electrophoretic Mobility Shift Assay; Glutathione; Humans; Luciferases; Lung Neoplasms; Precipitin Tests; Promoter Regions, Genetic; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2003
GSH depletion enhances adenoviral bax-induced apoptosis in lung cancer cells.
    Cancer gene therapy, 2004, Volume: 11, Issue:4

    Topics: Adenoviridae; Apoptosis; bcl-2-Associated X Protein; bcl-X Protein; Biological Assay; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Caspase 3; Caspases; Cell Line, Tumor; Combined Modality Therapy; Cytochromes c; Deoxyribonucleases; Gene Transfer Techniques; Genes, bcl-2; Genetic Vectors; Glutathione; Humans; Lung Neoplasms; Mitochondria; Oxidation-Reduction; Poly-ADP-Ribose Binding Proteins; Proto-Oncogene Proteins c-bcl-2

2004
Non-destructive micromethod for MRP1 functional assay in human lung tumor cells.
    Archives of toxicology, 2006, Volume: 80, Issue:3

    Topics: Acetylcysteine; ATP-Binding Cassette Transporters; Biological Assay; Biological Transport; Buthionine Sulfoximine; Cell Culture Techniques; Cell Line, Tumor; Dose-Response Relationship, Drug; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Fluorometry; Glutathione; Humans; Immunohistochemistry; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Propionates; Quinolines; Sensitivity and Specificity; Verapamil

2006
Factors involved in depletion of glutathione from A549 human lung carcinoma cells: implications for radiotherapy.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Radiation-Sensitizing Agents; Time Factors

1984
Depletion of intracellular GSH and NPSH by buthionine sulfoximine and diethyl maleate: factors that influence enhancement of aerobic radiation response.
    International journal of radiation oncology, biology, physics, 1984, Volume: 10, Issue:8

    Topics: Aerobiosis; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Radiation-Sensitizing Agents; Sulfhydryl Compounds; Time Factors

1984
Cellular glutathione depletion by diethyl maleate or buthionine sulfoximine: no effect of glutathione depletion on the oxygen enhancement ratio.
    Radiation research, 1983, Volume: 96, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Carcinoma; Cell Line; Cells, Cultured; Cricetinae; Dose-Response Relationship, Radiation; Glutathione; Humans; Hypoxia; Lung; Lung Neoplasms; Maleates; Methionine Sulfoximine; Oxygen Consumption; Radiation-Sensitizing Agents; Time Factors

1983
The role of thiols in cellular response to radiation and drugs.
    Radiation research, 1983, Volume: 95, Issue:3

    Topics: Animals; Azo Compounds; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chemical Phenomena; Chemistry; Cricetinae; Diamide; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Female; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Ovary; Oxygen; Radiation-Sensitizing Agents; Sulfhydryl Compounds

1983
Buthionine sulfoximine pretreatment potentiates the effect of isolated lung perfusion with doxorubicin.
    The Annals of thoracic surgery, 1995, Volume: 60, Issue:2

    Topics: Animals; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Chemotherapy, Cancer, Regional Perfusion; Doxorubicin; Drug Synergism; Glutathione; Hydroxyethyl Starch Derivatives; Liver; Lung Neoplasms; Male; Methionine Sulfoximine; Rats; Rats, Inbred F344; Sarcoma, Experimental

1995
Modulation of cisplatin resistance in acquired-resistant nonsmall cell lung cancer cells.
    Oncology research, 1995, Volume: 7, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cisplatin; DNA Repair; DNA, Neoplasm; Drug Interactions; Drug Resistance; Drug Screening Assays, Antitumor; Glutathione; Glutathione Transferase; Humans; Intracellular Fluid; Lung Neoplasms; Methionine Sulfoximine; Pentoxifylline; Tumor Cells, Cultured

1995
Regulation by glutathione of drug transport in multidrug-resistant human lung tumour cell lines overexpressing multidrug resistance-associated protein.
    British journal of cancer, 1995, Volume: 72, Issue:1

    Topics: Biological Transport; Buthionine Sulfoximine; Daunorubicin; Drug Resistance, Multiple; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Rhodamine 123; Rhodamines; RNA, Messenger; Tumor Cells, Cultured

1995
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-15, Volume: 92, Issue:17

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Arsenites; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cell Division; Cysteine; Drug Resistance, Multiple; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Multidrug Resistance-Associated Proteins; Recombinant Proteins; Transfection; Tumor Cells, Cultured

1995
Buthionine sulfoximine spares intracellular glutamate: a possible mechanism for cell growth stimulation.
    Cellular & molecular biology research, 1993, Volume: 39, Issue:7

    Topics: Analysis of Variance; Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Division; Cell Line; Chromatography, High Pressure Liquid; DNA Replication; Glutamates; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Thymidine; Tumor Cells, Cultured

1993
Exogenous glutathione attenuates the antiproliferative effect of buthionine sulfoximine.
    Toxicology, 1994, Mar-11, Volume: 88, Issue:1-3

    Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinoma; Cell Division; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured

1994
Selective in vivo accumulation of N-acetyl-4-S-cysteaminylphenol in B16F10 murine melanoma and enhancement of its in vitro and in vivo antimelanoma effect by combination of buthionine sulfoximine.
    Cancer research, 1994, May-15, Volume: 54, Issue:10

    Topics: Animals; Autoradiography; Buthionine Sulfoximine; Cysteamine; Dose-Response Relationship, Drug; Drug Synergism; Female; Glutathione; Lung Neoplasms; Melanoma, Experimental; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Phenols

1994
Buthionine sulfoximine enhances glutathione-but attenuates glutamate-stimulated cell proliferation.
    Cellular & molecular biology research, 1995, Volume: 41, Issue:2

    Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Carcinoma; Cell Division; Culture Media; Enzyme Inhibitors; Glutamic Acid; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured

1995
Decreased sensitivity to adriamycin in cadmium-resistant human lung carcinoma A549 cells.
    Biochemical pharmacology, 1997, Mar-07, Volume: 53, Issue:5

    Topics: Antibiotics, Antineoplastic; Buthionine Sulfoximine; Cadmium; Carcinogens, Environmental; Doxorubicin; Drug Resistance; Glutathione; Humans; Lung Neoplasms; Tumor Cells, Cultured

1997
Characterization of H+-ATPase-dependent activity of multidrug resistance-associated protein in homoharringtonine-resistant human leukemic K562 cells.
    Leukemia, 1998, Volume: 12, Issue:10

    Topics: Adenocarcinoma; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Cell Survival; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Harringtonines; Homoharringtonine; Humans; K562 Cells; Kinetics; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Proton-Translocating ATPases; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured

1998
Potentiation of benzo[a]pyrene-induced pulmonary and forestomach tumorigenesis in mice by D,L-buthionine-S,R-sulfoximine-mediated tissue glutathione depletion.
    Cancer letters, 2000, May-29, Volume: 153, Issue:1-2

    Topics: Animals; Antimetabolites; Benzo(a)pyrene; Buthionine Sulfoximine; Carcinogens; Drug Synergism; Female; Glutathione; Lung Neoplasms; Mice; Stomach Neoplasms

2000
Multidrug resistance protein MRP1 protects against the toxicity of the major lipid peroxidation product 4-hydroxynonenal.
    The Biochemical journal, 2000, Sep-01, Volume: 350 Pt 2

    Topics: Adenosine Triphosphate; Aldehydes; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Biological Transport; Buthionine Sulfoximine; Carcinoma, Small Cell; Cell Line; Cell Survival; Cysteine Proteinase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Humans; Immunoblotting; Insecta; Kinetics; Leukotriene Antagonists; Lipid Peroxidation; Lung Neoplasms; Multidrug Resistance-Associated Proteins; Oxidative Stress; Propionates; Quinolines; Recombinant Proteins; Time Factors; Tumor Cells, Cultured

2000
Chromium(VI)-induced mutagenesis in the lungs of big blue transgenic mice.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2000, Volume: 19, Issue:3

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Carcinogens; DNA; Dose-Response Relationship, Drug; Female; Glutathione; Instillation, Drug; Kidney; Liver; Lung; Lung Neoplasms; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutagenesis; Mutagens; Mutation; Potassium Dichromate; Trachea

2000
Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model.
    Cancer research, 2001, Nov-01, Volume: 61, Issue:21

    Topics: Acetylcysteine; Animals; Antimetabolites; Antineoplastic Agents, Alkylating; Aorta, Thoracic; Blood-Brain Barrier; Bone Marrow Diseases; Brain; Brain Neoplasms; Buthionine Sulfoximine; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione; Infusions, Intra-Arterial; Lung Neoplasms; Rats; Rats, Long-Evans; Tissue Distribution; Xenograft Model Antitumor Assays

2001
Modulation by D,L-buthionine-S,R-sulphoximine of etoposide cytotoxicity on human non-small cell lung, ovarian and breast carcinoma cell lines.
    European journal of cancer (Oxford, England : 1990), 1992, Volume: 28A, Issue:8-9

    Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cisplatin; Doxorubicin; Drug Synergism; Etoposide; Female; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil

1992
Combined in vitro modulation of adriamycin resistance.
    International journal of cancer, 1991, Oct-21, Volume: 49, Issue:4

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Carcinoma, Small Cell; Cell Line; Cell Survival; Doxorubicin; Drug Resistance; Glutathione; Humans; Lung Neoplasms; Membrane Glycoproteins; Methionine Sulfoximine; Neoplasm Proteins; Pleural Effusion

1991
Buthionine sulfoximine induced growth inhibition in human lung carcinoma cells does not correlate with glutathione depletion.
    Cell biology and toxicology, 1991, Volume: 7, Issue:3

    Topics: Buthionine Sulfoximine; Cell Division; Cell Survival; DNA, Neoplasm; Flow Cytometry; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Microscopy, Electron; Tumor Cells, Cultured

1991
The effect of doxorubicin on the glutathione content and viability of cultured human lung cancer cell lines A549 and GLC4 210.
    Clinica chimica acta; international journal of clinical chemistry, 1990, Dec-24, Volume: 194, Issue:2-3

    Topics: Adenocarcinoma; Buthionine Sulfoximine; Carcinoma, Small Cell; Cell Survival; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Doxorubicin; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Tumor Cells, Cultured

1990
Glutathione content and growth in A549 human lung carcinoma cells.
    Experimental cell research, 1990, Volume: 187, Issue:1

    Topics: Antimetabolites; Buthionine Sulfoximine; Cell Division; Cell Line; Glutathione; Humans; Kinetics; Lung Neoplasms; Methionine Sulfoximine; Time Factors; Tumor Cells, Cultured

1990
The role of glutathione in resistance to cisplatin in a human small cell lung cancer cell line.
    British journal of cancer, 1990, Volume: 62, Issue:1

    Topics: Antimetabolites; Buthionine Sulfoximine; Carcinoma; Cell Line; Cell Nucleus; Cell Survival; Cisplatin; DNA; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Neoplasm Proteins

1990
Selective modulation of glutathione levels in human normal versus tumor cells and subsequent differential response to chemotherapy drugs.
    Cancer research, 1986, Volume: 46, Issue:6

    Topics: Antineoplastic Agents; Bleomycin; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cisplatin; Glutathione; Humans; Lung; Lung Neoplasms; Melphalan; Methionine Sulfoximine; Neoplasms; Pyrrolidonecarboxylic Acid; Thiazoles; Thiazolidines; Zinostatin

1986
Enhanced cadmium cytotoxicity in A549 cells with reduced glutathione levels is due to neither enhanced cadmium accumulation nor reduced metallothionein synthesis.
    Cell biology and toxicology, 1989, Volume: 5, Issue:3

    Topics: Buthionine Sulfoximine; Cadmium; Glutathione; Humans; Lung Neoplasms; Maleates; Metallothionein; Methionine Sulfoximine; Sulfur Radioisotopes; Tumor Cells, Cultured

1989
Enhanced cytostatic activity of the sesquiterpene lactone eupatoriopicrin by glutathione depletion.
    British journal of cancer, 1989, Volume: 59, Issue:1

    Topics: Animals; Antimetabolites; Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Female; Glutathione; Lung Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Neoplasm Transplantation; Sesquiterpenes; Tumor Cells, Cultured

1989
Glutathione is involved in the early cadmium cytotoxic response in human lung carcinoma cells.
    Toxicology, 1988, Volume: 48, Issue:1

    Topics: Buthionine Sulfoximine; Cadmium; Drug Interactions; Glutathione; Humans; In Vitro Techniques; Lung Neoplasms; Methionine Sulfoximine

1988
Effect of cellular glutathione depletion on cadmium-induced cytotoxicity in human lung carcinoma cells.
    Cell biology and toxicology, 1987, Volume: 3, Issue:4

    Topics: Buthionine Sulfoximine; Cadmium; Cell Survival; Glutathione; Humans; Lung Neoplasms; Maleates; Methionine Sulfoximine; Tumor Cells, Cultured

1987
Combined effect of buthionine sulfoximine and cyclophosphamide upon murine tumours and bone marrow.
    British journal of cancer, 1986, Volume: 54, Issue:5

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Buthionine Sulfoximine; Cell Survival; Colony-Forming Units Assay; Cyclophosphamide; Cysteine; Glutathione; Lung Neoplasms; Male; Methionine Sulfoximine; Mice; Mice, Inbred C3H

1986
Buthionine sulfoximine inhibition of cystine uptake and glutathione biosynthesis in human lung carcinoma cells.
    Toxicology and applied pharmacology, 1985, Mar-15, Volume: 77, Issue:3

    Topics: Buthionine Sulfoximine; Cell Line; Cysteine; Cystine; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Sulfur Radioisotopes

1985