Page last updated: 2024-08-22

buthionine sulfoximine and Leukemia

buthionine sulfoximine has been researched along with Leukemia in 18 studies

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19902 (11.11)18.7374
1990's6 (33.33)18.2507
2000's8 (44.44)29.6817
2010's1 (5.56)24.3611
2020's1 (5.56)2.80

Authors

AuthorsStudies
Chen, Y; Fu, W; Guo, J; Hu, F; Jiang, H; Li, J; Liu, K; Liu, Y; Shan, C; Wang, J; Zhang, C; Zhang, M1
Chen, G; Chen, Z; Hu, Y; Huang, P1
Barge, RM; Honders, MW; Spoelder, HE; Veuger, MJ; Willemze, R1
Adjei, AA; Bone, N; Bruzek, LM; Chandra, J; Hackbarth, J; Karp, JE; Kaufmann, SH; Kay, NE; Le, S; Loegering, D; Narayanan, VL; Sausville, EA; Tefferi, A1
Fujii, H; Goto, H; Ikuta, K; Takahashi, H; Yokota, S1
Antony, S; Fu, H; Kohlhagen, G; Liao, Z; Liu, H; Pommier, Y; Sordet, O; Stevens, EV1
Assreuy, J; Freitas, MS; Santos-Silva, MC1
Chan, R; Chen, D; Jing, Y; Waxman, S1
Frgala, T; Kalous, O; Proffitt, RT; Reynolds, CP1
Czyz, M; Duechler, M; Stańczyk, M; Stepnik, M1
Baguley, BC; Davey, MW; Davey, RA; Hargrave, RM; Harvie, RM; Su, GM1
Gantchev, TG; Hunting, DJ1
Davey, MW; Davey, RA; Grech, KV1
Cai, X; Chen, G; Shen, Y1
Jollow, DJ; Peters, RH; Stuart, RK1
Larsson, R; Nygren, P1
Cullen, MK; Kobb, SM; Miller, AM; Weiner, RS1
Inaba, M; Iwata, K; Kubodera, A; Ozawa, S1

Other Studies

18 other study(ies) available for buthionine sulfoximine and Leukemia

ArticleYear
A rational foundation for micheliolide-based combination strategy by targeting redox and metabolic circuit in cancer cells.
    Biochemical pharmacology, 2022, Volume: 200

    Topics: Apoptosis; Buthionine Sulfoximine; Glioblastoma; Glutathione; Humans; Leukemia; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; Sesquiterpenes, Guaiane

2022
Inhibition of mitochondrial respiration and rapid depletion of mitochondrial glutathione by β-phenethyl isothiocyanate: mechanisms for anti-leukemia activity.
    Antioxidants & redox signaling, 2011, Dec-15, Volume: 15, Issue:12

    Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Line, Tumor; Cell Respiration; Cell Survival; Electron Transport Complex I; Glutathione; HL-60 Cells; Humans; Isothiocyanates; Leukemia; Membrane Potentials; Mitochondria; Models, Biological; NADH Dehydrogenase; Nitric Oxide; Reactive Oxygen Species

2011
Inactivation of deoxycytidine kinase and overexpression of P-glycoprotein in AraC and daunorubicin double resistant leukemic cell lines.
    Leukemia research, 2003, Volume: 27, Issue:5

    Topics: 2-Chloroadenosine; Alternative Splicing; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Azacitidine; Biological Transport; Buthionine Sulfoximine; Calcium Channel Blockers; Cytarabine; Daunorubicin; Decitabine; Deoxyadenosines; Deoxycytidine Kinase; DNA Mutational Analysis; DNA, Neoplasm; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glutathione; Humans; Idarubicin; Leukemia; Methotrexate; Neoplasm Proteins; Rats; Reverse Transcriptase Polymerase Chain Reaction; Tumor Cells, Cultured; Verapamil

2003
Involvement of reactive oxygen species in adaphostin-induced cytotoxicity in human leukemia cells.
    Blood, 2003, Dec-15, Volume: 102, Issue:13

    Topics: Acetylcysteine; Adamantane; Antioxidants; Apoptosis; Buthionine Sulfoximine; DNA Damage; DNA, Neoplasm; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Glutathione; Humans; Hydroquinones; K562 Cells; Leukemia; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Leukemia, Myeloid; Neoplasm Proteins; Neoplastic Stem Cells; Quinones; Reactive Oxygen Species; Tumor Stem Cell Assay; Tyrphostins

2003
N-(4-Hydroxyphenyl)retinamide (4-HPR) induces leukemia cell death via generation of reactive oxygen species.
    International journal of hematology, 2003, Volume: 78, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Buthionine Sulfoximine; Cell Line, Tumor; Dose-Response Relationship, Drug; Fenretinide; Glutathione; Humans; Leukemia; Oxidative Stress; Reactive Oxygen Species

2003
Topoisomerase I-DNA complexes contribute to arsenic trioxide-induced apoptosis.
    The Journal of biological chemistry, 2004, Aug-06, Volume: 279, Issue:32

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Caspase 3; Caspase Inhibitors; Caspases; DNA; DNA Fragmentation; DNA Topoisomerases, Type I; Enzyme Activation; Enzyme Inhibitors; Flow Cytometry; Gene Expression; Gene Silencing; Humans; Leukemia; Oxides; Proto-Oncogene Proteins c-bcl-2; Reactive Oxygen Species; Recombinant Proteins; Tumor Cells, Cultured

2004
Involvement of NF-kappaB and glutathione in cytotoxic effects of nitric oxide and taxol on human leukemia cells.
    Leukemia research, 2006, Volume: 30, Issue:2

    Topics: Buthionine Sulfoximine; Carmustine; Cell Line, Tumor; Glutathione; Humans; Leukemia; NF-kappa B; Nitric Oxide; Paclitaxel; Proline; S-Nitroso-N-Acetylpenicillamine; Thiocarbamates

2006
Buthionine sulfoximine enhancement of arsenic trioxide-induced apoptosis in leukemia and lymphoma cells is mediated via activation of c-Jun NH2-terminal kinase and up-regulation of death receptors.
    Cancer research, 2006, Dec-01, Volume: 66, Issue:23

    Topics: Amino Acid Chloromethyl Ketones; Anthracenes; Apoptosis; Arsenic Trioxide; Arsenicals; Blotting, Western; Buthionine Sulfoximine; Caspase 3; Caspase Inhibitors; Cell Proliferation; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Glutathione; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Jurkat Cells; Leukemia; Lymphoma; Oxides; Receptors, TNF-Related Apoptosis-Inducing Ligand; Time Factors; U937 Cells

2006
A fluorescence microplate cytotoxicity assay with a 4-log dynamic range that identifies synergistic drug combinations.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Cell Proliferation; Drug Screening Assays, Antitumor; Drug Synergism; Enzyme Inhibitors; Eosine Yellowish-(YS); Fenretinide; Fluorescent Dyes; Humans; Leukemia; Melphalan; Microscopy, Fluorescence; Neuroblastoma; Protein Kinase C; Sphingosine; Tumor Cells, Cultured; Tumor Stem Cell Assay

2007
Potentiation of arsenic trioxide cytotoxicity by Parthenolide and buthionine sulfoximine in murine and human leukemic cells.
    Cancer chemotherapy and pharmacology, 2008, Volume: 61, Issue:5

    Topics: Adenosine Triphosphate; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; DNA Fragmentation; Drug Synergism; Flow Cytometry; Glutamate-Cysteine Ligase; Glutathione; Humans; Leukemia; Mice; Microscopy, Fluorescence; NF-kappa B; Oxides; Reactive Oxygen Species; Sesquiterpenes

2008
The potential of N-[2-(dimethylamino)ethyl]acridine-4-carboxamide to circumvent three multidrug-resistance phenotypes in vitro.
    Cancer chemotherapy and pharmacology, 1997, Volume: 39, Issue:5

    Topics: Acridines; Amsacrine; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Line; Cell Survival; Daunorubicin; Drug Resistance, Multiple; HL-60 Cells; Humans; Idarubicin; Leukemia; Paclitaxel; Phenotype; RNA, Messenger; Transcription, Genetic; Tumor Cells, Cultured; Verapamil

1997
Enhancement of etoposide (VP-16) cytotoxicity by enzymatic and photodynamically induced oxidative stress.
    Anti-cancer drugs, 1997, Volume: 8, Issue:2

    Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Buthionine Sulfoximine; Cytoplasm; DNA Damage; Drug Synergism; Electron Spin Resonance Spectroscopy; Etoposide; Free Radicals; Glutathione; Humans; Indoles; Leukemia; Organometallic Compounds; Oxidative Stress; Photosensitizing Agents; Tumor Cells, Cultured

1997
The relationship between modulation of MDR and glutathione in MRP-overexpressing human leukemia cells.
    Biochemical pharmacology, 1998, Apr-15, Volume: 55, Issue:8

    Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Buthionine Sulfoximine; Cell Division; Daunorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Etoposide; Gene Expression Regulation, Neoplastic; Genes, MDR; Glutathione; Humans; Leukemia; Multidrug Resistance-Associated Proteins; Tumor Cells, Cultured

1998
[Glutathione synthesis inhibitor enhances arsenic trioxide-induced apoptosis].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 1999, Volume: 21, Issue:4

    Topics: Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Glutathione; Humans; Leukemia; Lymphoma; Oxides; Tumor Cells, Cultured

1999
Role of glutathione in the in vitro synergism between 4-hydroperoxy-cyclophosphamide and cisplatin in leukemia cell lines.
    Cancer research, 1991, May-15, Volume: 51, Issue:10

    Topics: Animals; Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Cell Survival; Cisplatin; Cyclophosphamide; Drug Screening Assays, Antitumor; Drug Synergism; Glutathione; Humans; Kinetics; Leukemia; Leukemia, Experimental; Methionine Sulfoximine

1991
Differential in vitro sensitivity of human tumor and normal cells to chemotherapeutic agents and resistance modulators.
    International journal of cancer, 1991, Jun-19, Volume: 48, Issue:4

    Topics: Adenocarcinoma; Antineoplastic Agents; Buthionine Sulfoximine; Cell Division; Cell Line; Cell Survival; Cisplatin; Cyclosporins; Doxorubicin; Drug Screening Assays, Antitumor; Etoposide; Humans; Kidney Neoplasms; Kinetics; Leukemia; Lymphocytes; Methionine Sulfoximine; Neurilemmoma; Tumor Cells, Cultured; Verapamil; Vincristine

1991
Effects of lipoxygenase and glutathione pathway inhibitors on leukemic cell line growth.
    The Journal of laboratory and clinical medicine, 1989, Volume: 113, Issue:3

    Topics: Buthionine Sulfoximine; Caffeic Acids; Dose-Response Relationship, Drug; Glutathione; Hematopoietic Stem Cells; Humans; Leukemia; Leukotrienes; Lipoxygenase; Lipoxygenase Inhibitors; Masoprocol; Methionine Sulfoximine; Tumor Cells, Cultured

1989
Intracellular glutathione levels in human colon cancer cells naturally resistant to cross-linking agents.
    Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:7

    Topics: Antimetabolites; Buthionine Sulfoximine; Cisplatin; Colonic Neoplasms; Cross-Linking Reagents; Drug Resistance; Glutathione; Humans; Leukemia; Methionine Sulfoximine; Nimustine; Tumor Cells, Cultured

1989