Compounds > buthionine sulfoximine
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buthionine sulfoximine and Head and Neck Neoplasms

buthionine sulfoximine has been researched along with Head and Neck Neoplasms in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jang, H; Kim, EH; Roh, JL; Shin, D1
Ahmad, IM; Aykin-Burns, N; Dayal, D; Dornfeld, KJ; Li, L; Mattson, DM; Orcutt, KP; Parsons, AD; Simons, AL; Spitz, DR1
Ardail, D; Boivin, A; Hanot, M; Maalouf, M; Malesys, C; Rodriguez-Lafrasse, C; Rousson, R1
Fletcher, EV; Knudson, CM; Love-Homan, L; Martin, SM; Parsons, AD; Simons, AL; Sobhakumari, A; Spitz, DR1
Ahmad, IM; Dornfeld, KJ; Mattson, DM; Simons, AL; Spitz, DR1
Andrews, PA; Cullen, KJ; Heffern, J; Newkirk, K; Rasmussen, AA; Sessions, RB; Sloman-Moll, E1
Bier, H1

Other Studies

7 other study(ies) available for buthionine sulfoximine and Head and Neck Neoplasms

ArticleYear
Targeting of the Glutathione, Thioredoxin, and Nrf2 Antioxidant Systems in Head and Neck Cancer.
    Antioxidants & redox signaling, 2017, 07-10, Volume: 27, Issue:2

    Topics: Animals; Auranofin; Buthionine Sulfoximine; Cell Line, Tumor; Cell Proliferation; Cell Survival; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Glutathione; Head and Neck Neoplasms; Humans; Mice; NF-E2-Related Factor 2; Signal Transduction; Thioredoxins; Xenograft Model Antitumor Assays

2017
Cisplatin combined with zidovudine enhances cytotoxicity and oxidative stress in human head and neck cancer cells via a thiol-dependent mechanism.
    Free radical biology & medicine, 2009, Jan-15, Volume: 46, Issue:2

    Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cisplatin; Drug Therapy, Combination; Glutathione; Head and Neck Neoplasms; Humans; Membrane Potential, Mitochondrial; Mitochondria; Oxidative Stress; Sulfhydryl Compounds; Zidovudine

2009
Transient alteration of cellular redox buffering before irradiation triggers apoptosis in head and neck carcinoma stem and non-stem cells.
    PloS one, 2011, Jan-19, Volume: 6, Issue:1

    Topics: Adaptation, Physiological; Apoptosis; bcl-2-Associated X Protein; Buffers; Buthionine Sulfoximine; Carcinoma; Carcinoma, Squamous Cell; Cell Line, Tumor; Dimethyl Fumarate; Fumarates; Glutathione; Head and Neck Neoplasms; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; Neoplasms, Squamous Cell; Neoplastic Stem Cells; Oxidation-Reduction; Squamous Cell Carcinoma of Head and Neck

2011
Susceptibility of human head and neck cancer cells to combined inhibition of glutathione and thioredoxin metabolism.
    PloS one, 2012, Volume: 7, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Auranofin; Buthionine Sulfoximine; Carcinoma, Squamous Cell; Catalase; Cell Line, Tumor; Cell Survival; Drug Synergism; Erlotinib Hydrochloride; Female; Gene Knockdown Techniques; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Head and Neck Neoplasms; Humans; Mice; Mice, Nude; Necrosis; Oxidation-Reduction; Oxidative Stress; Peroxiredoxins; Quinazolines; RNA, Small Interfering; Thioredoxin-Disulfide Reductase; Thioredoxins; Xenograft Model Antitumor Assays

2012
2-Deoxy-D-glucose combined with cisplatin enhances cytotoxicity via metabolic oxidative stress in human head and neck cancer cells.
    Cancer research, 2007, Apr-01, Volume: 67, Issue:7

    Topics: Acetylcysteine; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Carcinoma, Squamous Cell; Catalase; Cell Growth Processes; Cisplatin; Deoxyglucose; Drug Synergism; Glutathione; Head and Neck Neoplasms; Humans; Oxidative Stress; Polyethylene Glycols; Superoxide Dismutase

2007
Glutathione content but not gamma glutamyl cysteine synthetase mRNA expression predicts cisplatin resistance in head and neck cancer cell lines.
    Cancer chemotherapy and pharmacology, 1997, Volume: 40, Issue:1

    Topics: Buthionine Sulfoximine; Drug Resistance; Glutamate-Cysteine Ligase; Glutathione; Head and Neck Neoplasms; Humans; RNA, Messenger; Tumor Cells, Cultured

1997
Circumvention of drug resistance in cisplatin-resistant sublines of the human squamous carcinoma cell line HLac 79 in vitro and in vivo.
    Acta oto-laryngologica, 1991, Volume: 111, Issue:4

    Topics: Animals; Antimetabolites, Antineoplastic; Aphidicolin; Buthionine Sulfoximine; Carcinoma, Squamous Cell; Cisplatin; Cyclosporins; Dose-Response Relationship, Drug; Drug Resistance; Drug Screening Assays, Antitumor; Female; Glutathione; Head and Neck Neoplasms; Humans; Methionine Sulfoximine; Mice; Mice, Nude; Tumor Cells, Cultured; Verapamil

1991