buthionine sulfoximine has been researched along with Glioma in 31 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (9.68) | 18.7374 |
| 1990's | 11 (35.48) | 18.2507 |
| 2000's | 12 (38.71) | 29.6817 |
| 2010's | 5 (16.13) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blattmann, H; Bräuer-Krisch, E; Hildebrandt, G; Laissue, JA; Requardt, H; Schültke, E | 1 |
| Kayama, T; Kitanaka, C; Narita, Y; Okada, M; Sato, A; Seino, S; Shibui, S; Shibuya, K; Watanabe, E | 1 |
| Gülden, M; Klauser, E; Maser, E; Seibert, H; Seibert, S | 1 |
| Belizário, JE; de Andrade-Lima, LC; Garcia, CC; Menck, CF; Munford, V; Quinet, A; Rocha, CR; Vieira, DB | 1 |
| Fortunato, RS; Kajitani, GS; Menck, CF; Quinet, A; Rocha, CR | 1 |
| Boudard, D; Denoyer, D; Dubois, F; Koumanov, F; Perek, N | 1 |
| Chopp, M; Espiritu, M; Jiang, F; Katakowski, M; Robin, AM; Singh, G; Tong, L | 1 |
| Higuchi, Y; Yoshimoto, T | 1 |
| Kumada, H; Matsumura, A; Nakai, K; Yamamoto, T; Yoshida, F | 1 |
| Denoyer, D; Dubois, F; Le Jeune, N; Perek, N | 1 |
| Ali-Osman, F; Antoun, G; Gagucas, E; Rajagopal, S; Wang, H | 1 |
| Domann, FE; Oberley, LW; Oberley, TD; St Clair, DK; Yan, T; Zhong, W | 1 |
| Han, D; Kobayashi, MS; Packer, L; Roy, S; Sen, CK; Tritschler, HJ | 1 |
| Baumgart, J; Dichgans, J; Klockgether, T; Reber, U; Seyfried, J; Trepel, M; Weller, M; Wüllner, U | 1 |
| Hirota, N; Iida, M; Kuribayashi, N; Matsumoto, K; Sakagami, H; Sunaga, S; Takeda, M | 1 |
| Lim, R; Oberley, LW; Yan, T; Zhong, W | 1 |
| Pentreath, VW; Slamon, ND | 1 |
| Baraban, J; Brem, H; Burger, PC; Li, KW; Piantadosi, S; Ratan, R; Sipos, EP; Witham, TF | 1 |
| Almeida , A; Bolaños, JP; Vásquez, OL | 1 |
| Anderson, CP; Bleyer, WA; Cairncross, JG; Cloughesy, T; Doolittle, ND; Eck, SL; Guastadisegni, P; Hall, WA; Muldoon, LL; Neuwelt, EA; Patel, SJ; Peereboom, D; Siegal, T | 1 |
| Butler, J; Pentreath, VW; Slamon, ND; Ward, TH | 1 |
| Ha, MS; Kim, YK; Lee, YW | 1 |
| Baumgart, J; Seyfried, J; Stock, J; Weller, M; Wick, W; Wüllner, U | 1 |
| Bigner, DD; Brizel, DM; Friedman, HS; Griffith, OW; Halperin, EC; Honore, G; Sontag, MR | 1 |
| Allalunis-Turner, MJ; Allen, PB; Aronyk, KE; Day, RS; Fulton, DS; Huyser-Wierenga, D; McKean, JD; Petruk, KC; Urtasun, RC; Weir, BK | 1 |
| Hotta, T; Kawamoto, K; Kiya, K; Kurisu, K; Mikami, T; Nakada, Y; Saito, Y; Uozumi, T; Yamada, K | 1 |
| Bigner, DD; Fekete, I; Friedman, HS; Griffith, OW; Groothuis, DR; Schlageter, KE | 1 |
| Bigner, DD; Colvin, OM; Friedman, HS; Griffith, OW; Halperin, EC; Honore, G; Lippitz, BE; Ostertag, CB | 1 |
| Bodell, WJ; Doane-Setzer, P; Evans, CG; Smith, MT; Tokuda, K | 1 |
| Bigner, DD; Colvin, OM; Elion, GB; Friedman, HS; Griffith, OW; Hilton, J; Lippitz, B; Schold, SC | 1 |
| Bigner, DD; Colapinto, EV; Colvin, OM; Elion, GB; Friedman, HS; Griffith, OW; Groothuis, DR; Hilton, J; Lee, Y; Skapek, SX | 1 |
31 other study(ies) available for buthionine sulfoximine and Glioma
| Article | Year |
|---|---|
Survival of rats bearing advanced intracerebral F 98 tumors after glutathione depletion and microbeam radiation therapy: conclusions from a pilot project.
Topics: Animals; Antimetabolites; Brain Neoplasms; Buthionine Sulfoximine; Combined Modality Therapy; Dose-Response Relationship, Radiation; Glioma; Glutathione; Male; Pilot Projects; Radiotherapy; Rats; Rats, Inbred F344; Survival Rate; Synchrotrons | 2018 |
Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells.
Topics: Acetylcysteine; Animals; Brain Neoplasms; Buthionine Sulfoximine; Cell Differentiation; Down-Regulation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glioma; Humans; Hydrogen Peroxide; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 7; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; RNA Interference; Transplantation, Heterologous | 2014 |
Additivity, antagonism, and synergy in arsenic trioxide-induced growth inhibition of C6 glioma cells: effects of genistein, quercetin and buthionine-sulfoximine.
Topics: Animals; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Line, Tumor; Genistein; Glioma; Oxides; Quercetin; Rats | 2014 |
Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo.
Topics: Animals; Apoptosis; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cisplatin; Dacarbazine; Disease Progression; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Female; Glioma; Glutathione; Humans; Mice, Nude; Temozolomide; Tumor Suppressor Protein p53 | 2014 |
NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Female; Glioma; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; NF-E2-Related Factor 2; Temozolomide; Xenograft Model Antitumor Assays | 2016 |
Modulation of the multidrug resistance of glioma by glutathione levels depletion--interaction with Tc-99M-Sestamibi and Tc-99M-Tetrofosmin.
Topics: Annexin A5; Antimetabolites; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Blotting, Western; Buthionine Sulfoximine; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glioma; Glutathione; Humans; Membrane Potentials; Mitochondria; Multidrug Resistance-Associated Proteins; Organophosphorus Compounds; Organotechnetium Compounds; Radiopharmaceuticals; Technetium Tc 99m Sestamibi; Tumor Cells, Cultured | 2002 |
Photodynamic therapy with photofrin in combination with Buthionine Sulfoximine (BSO) of human glioma in the nude rat.
Topics: Animals; Buthionine Sulfoximine; Dihematoporphyrin Ether; Drug Therapy, Combination; Glioma; Glutathione; Humans; Male; Photochemotherapy; Photosensitizing Agents; Rats; Rats, Nude; Tumor Cells, Cultured | 2003 |
Promoting effects of polyunsaturated fatty acids on chromosomal giant DNA fragmentation associated with cell death induced by glutathione depletion.
Topics: Animals; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Chromosomes; DNA; DNA Fragmentation; Fatty Acids, Unsaturated; Glioma; Glutamic Acid; Glutathione; Lipid Peroxidation; Rats; Time Factors | 2004 |
Enhancement of sodium borocaptate (BSH) uptake by tumor cells induced by glutathione depletion and its radiobiological effect.
Topics: Animals; Borohydrides; Boron Neutron Capture Therapy; Brain Neoplasms; Buthionine Sulfoximine; Carcinoma, Squamous Cell; Cells, Cultured; Cricetinae; Down-Regulation; Gamma Rays; Glioma; Glutathione; Lung; Mice; Radiation-Sensitizing Agents; Rats; Relative Biological Effectiveness; Sulfhydryl Compounds | 2004 |
Influence of glutathione depletion on plasma membrane cholesterol esterification and on Tc-99m-sestamibi and Tc-99m-tetrofosmin uptakes: a comparative study in sensitive U-87-MG and multidrug-resistant MRP1 human glioma cells.
Topics: Biological Transport; Buthionine Sulfoximine; Cell Line, Tumor; Cholesterol Esters; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glioma; Glutathione; Humans; Membrane Lipids; Multidrug Resistance-Associated Proteins; Organophosphorus Compounds; Organotechnetium Compounds; Technetium Tc 99m Sestamibi | 2004 |
Buthionine sulfoximine induction of gamma-L-glutamyl-L-cysteine synthetase gene expression, kinetics of glutathione depletion and resynthesis, and modulation of carmustine-induced DNA-DNA cross-linking and cytotoxicity in human glioma cells.
Topics: Antineoplastic Agents, Alkylating; Base Sequence; Buthionine Sulfoximine; Carmustine; Cell Survival; DNA; Dose-Response Relationship, Drug; Gene Expression Regulation, Enzymologic; Glioma; Glutamate-Cysteine Ligase; Glutathione; Humans; Kinetics; Methionine Sulfoximine; Molecular Sequence Data | 1996 |
Inhibition of cell growth and sensitization to oxidative damage by overexpression of manganese superoxide dismutase in rat glioma cells.
Topics: Animals; Antineoplastic Agents, Alkylating; Buthionine Sulfoximine; Carmustine; Catalase; Cell Division; Enzyme Inhibitors; Female; Gamma Rays; Gene Expression; Glioma; Glutamate-Cysteine Ligase; Glutathione Peroxidase; Humans; Mice; Mice, Nude; Oxidative Stress; Pyruvic Acid; Radiation Tolerance; Rats; RNA, Messenger; RNA, Neoplasm; Superoxide Dismutase; Transfection; Tumor Cells, Cultured | 1996 |
Protection against glutamate-induced cytotoxicity in C6 glial cells by thiol antioxidants.
Topics: Acetylcysteine; Animals; Antioxidants; Buthionine Sulfoximine; Cell Survival; Excitatory Amino Acid Antagonists; Glioma; Glutamic Acid; Glutathione; Kinetics; Rats; Thioctic Acid; Tumor Cells, Cultured | 1997 |
Potentiation of treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells: the role of bcl-2.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Busulfan; Buthionine Sulfoximine; Drug Synergism; Gene Transfer Techniques; Glioma; Glutathione; Humans; Prohibitins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1998 |
Effect of glutathione-modulating compounds on hydrogen-peroxide-induced cytotoxicity in human glioblastoma and glioma cell lines.
Topics: Acetylcysteine; Buthionine Sulfoximine; Cell Survival; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; Glioblastoma; Glioma; Glutathione; Humans; Hydrogen Peroxide; Tumor Cells, Cultured | 1997 |
Expression of superoxide dismutases, catalase, and glutathione peroxidase in glioma cells.
Topics: Animals; Blotting, Western; Buthionine Sulfoximine; Carmustine; Catalase; Fluorescent Antibody Technique; Gene Expression; Glioma; Glutathione Peroxidase; Humans; Rats; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Superoxide Dismutase; Tumor Cells, Cultured | 1999 |
Antioxidant defense against antidepressants in C6 and 1321N1 cells.
Topics: 1-Methyl-3-isobutylxanthine; Adrenergic beta-Agonists; Animals; Antidepressive Agents; Antimetabolites; Antioxidants; Astrocytes; Astrocytoma; Bucladesine; Buthionine Sulfoximine; Cyclic AMP; Drug Interactions; Glioma; Glutathione; Humans; Isoproterenol; Neuroprotective Agents; Oxidative Stress; Phosphodiesterase Inhibitors; Rats; Tumor Cells, Cultured | 2000 |
L-buthionine sulfoximine potentiates the antitumor effect of 4-hydroperoxycyclophosphamide when administered locally in a rat glioma model.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Brain; Brain Neoplasms; Buthionine Sulfoximine; Cyclophosphamide; Drug Combinations; Drug Implants; Drug Synergism; Glioma; Glutathione; Injections, Intraperitoneal; Liver; Male; Rats; Rats, Inbred F344; Reference Values; Survival Analysis | 2001 |
Depletion of glutathione up-regulates mitochondrial complex I expression in glial cells.
Topics: Animals; Animals, Newborn; Astrocytes; Buthionine Sulfoximine; Cells, Cultured; Citrate (si)-Synthase; Electron Transport Complex I; Electron Transport Complex II; Gene Expression Regulation, Enzymologic; Glioma; Glutathione; Multienzyme Complexes; NADH, NADPH Oxidoreductases; Neuroglia; Oxidoreductases; Prosencephalon; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Succinate Dehydrogenase; Tumor Cells, Cultured | 2001 |
Importance of dose intensity in neuro-oncology clinical trials: summary report of the Sixth Annual Meeting of the Blood-Brain Barrier Disruption Consortium.
Topics: Adult; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Bone Marrow Diseases; Bone Marrow Transplantation; Brain Neoplasms; Buthionine Sulfoximine; Child; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Dose-Response Relationship, Drug; Drug Synergism; Genetic Therapy; Genetic Vectors; Glioma; Glutathione; Guinea Pigs; Hearing Loss, Sensorineural; Hematopoietic Stem Cell Transplantation; Humans; Hypertonic Solutions; Lymphoma, Non-Hodgkin; Meningeal Neoplasms; Multicenter Studies as Topic; Neuroblastoma; Oligodendroglioma; Permeability; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
Assessment of DNA damage in C6 glioma cells after antidepressant treatment using an alkaline comet assay.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Antidepressive Agents, Second-Generation; Antidepressive Agents, Tricyclic; Bucladesine; Buthionine Sulfoximine; Comet Assay; DNA Damage; Enzyme Inhibitors; Glioma; Glutathione; Phosphodiesterase Inhibitors; Rats; Tumor Cells, Cultured | 2001 |
Role of reactive oxygen species and glutathione in inorganic mercury-induced injury in human glioma cells.
Topics: Brain Neoplasms; Buthionine Sulfoximine; Cell Survival; Fluorescent Dyes; Free Radical Scavengers; Glioma; Glutathione; Humans; Kinetics; Mercuric Chloride; Nitroarginine; Reactive Oxygen Species; Spectrometry, Fluorescence; Tumor Cells, Cultured; Uric Acid | 2001 |
CD95/CD95 ligand-independent potentiation of treosulfan cytotoxicity by BSO in malignant glioma cells in vitro and in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Blood Cell Count; Brain Neoplasms; Busulfan; Buthionine Sulfoximine; Cell Division; Drug Synergism; Fas Ligand Protein; fas Receptor; Gene Transfer Techniques; Glioma; Glutathione; Humans; In Vitro Techniques; Ligands; Membrane Glycoproteins; Neoplasm Transplantation; Rats; Rats, Sprague-Dawley; Survival Rate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
The radiation dose-response relationship in a human glioma xenograft and an evaluation of the influence of glutathione depletion by buthionine sulfoximine.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Dose-Response Relationship, Radiation; Glioma; Glutathione; Humans; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Radiation-Sensitizing Agents; Survival Rate; Transplantation, Heterologous | 1992 |
Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Child; Drug Screening Assays, Antitumor; Drug Synergism; Female; Glioma; Glutathione; Humans; Male; Mechlorethamine; Methionine Sulfoximine; Middle Aged; Tumor Cells, Cultured | 1991 |
Glutathione and cellular response of ACNU-resistant rat glioma sublines to drugs and radiation.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Cell Survival; Dose-Response Relationship, Radiation; Doxorubicin; Drug Resistance; Etoposide; Glioma; Glutathione; Kinetics; Methionine Sulfoximine; Nimustine; Pyrrolidonecarboxylic Acid; Rats; Thiazoles; Thiazolidines; Vinblastine | 1991 |
Rate of buthionine sulfoximine entry into brain and xenotransplanted human gliomas.
Topics: Animals; Brain; Brain Neoplasms; Buthionine Sulfoximine; Capillaries; Diffusion; Glioma; Humans; Methionine Sulfoximine; Mice; Mice, Nude; Transplantation, Heterologous | 1990 |
L-buthionine-sulfoximine-mediated radiosensitization in experimental interstitial radiotherapy of intracerebral D-54 MG glioma xenografts in athymic mice.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Glioma; Male; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Radiation-Sensitizing Agents | 1990 |
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Dinitrochlorobenzene; Drug Resistance; gamma-Glutamyltransferase; Glioma; Glutathione; Glutathione Transferase; Lomustine; Mechlorethamine; Methionine Sulfoximine; Rats; Semustine | 1987 |
Increased melphalan activity in intracranial human medulloblastoma and glioma xenografts following buthionine sulfoximine-mediated glutathione depletion.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Drug Interactions; Female; Glioma; Glutathione; Humans; Male; Medulloblastoma; Melphalan; Methionine Sulfoximine; Mice; Mice, Nude; Neoplasm Transplantation | 1989 |
Buthionine sulfoximine-mediated depletion of glutathione in intracranial human glioma-derived xenografts.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Female; Glioma; Glutathione; Humans; Male; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Transplantation, Heterologous | 1988 |