buthionine sulfoximine has been researched along with Disease Models, Animal in 71 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (2.82) | 18.7374 |
1990's | 11 (15.49) | 18.2507 |
2000's | 26 (36.62) | 29.6817 |
2010's | 28 (39.44) | 24.3611 |
2020's | 4 (5.63) | 2.80 |
Authors | Studies |
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Braisted, J; Dranchak, P; Earnest, TW; Gu, X; Hoon, MA; Inglese, J; Oliphant, E; Solinski, HJ | 1 |
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV | 1 |
Abhyankar, S; Adelusi, O; Apte, U; Dawn, B; Duan, L; Jaeschke, H; Nguyen, NT; Ramachandran, A; Robarts, DR; Soder, RP; Umbaugh, DS; Woolbright, B | 1 |
Fereshetyan, K; Harutyunyan, H; Karapetyan, G; Yenkoyan, K | 1 |
Bilska-Wilkosz, A; Chwatko, G; Górny, M; Iciek, M; Kajta, M; Kamińska, A; Kamińska, K; Lorenc-Koci, E; Rogóż, Z; Wnuk, A | 1 |
Kerry, Z; Ozsarlak-Sozer, G; Sevin, G; Sozer, N | 1 |
Brown, IAM; Gulbransen, BD | 1 |
Blanco, L; Fernández, CI; Fernández, JL; González-Fraguela, ME; Lorigados, L; Serrano, T | 1 |
Akai, S; Matsubara, A; Oda, S; Tsuneyama, K; Yokoi, T | 1 |
Jia, R; Matsubara, A; Oda, S; Yokoi, T | 1 |
Alkadhi, KA; Allam, F; Asghar, M; Bohat, R; Chugh, G; Dao, AT; Jafri, F; Mowrey, C; Patki, G; Salim, S | 1 |
Fukami, T; Iida, A; Matsuo, K; Nakajima, M; Sasaki, E; Tsuneyama, K; Yokoi, T | 1 |
Andersen, JK; Chinta, SJ; Rajagopalan, S | 1 |
Bertholet, L; Meunier, C; Preissmann, D; Schenk, F | 1 |
Alharbi, MM; Alharbi, NO; Imam, F; Nadeem, A; Sayed-Ahmed, MM; Siddiqui, N | 1 |
Alharbi, MM; Alharbi, NO; Imam, F; Nadeem, A; Siddiqui, N | 1 |
Hatao, K; Kimura, T; Kodama, T; Kumada, K; Kumano, A; Mori, K; Takano, N; Takiguchi, S | 1 |
Banday, AA; Bhatt, SR; Lokhandwala, MF | 1 |
Dépré, M; Gisquet-Verrier, P; Preissmann, D; Schenk, F | 1 |
Ahmad, SF; Al-Harbi, MM; Al-Harbi, NO; Alotaibi, MR; AlSaad, AM; Ansari, MA; Nadeem, A | 1 |
Akai, S; Oda, S; Yokoi, T | 1 |
Oshima, J; Reliene, R; Schiestl, RH; Yamamoto, ML | 1 |
Coelho, IS; Dafre, AL; Franco, JL; Meotti, FC; Rocha, JB; Santos, AR | 1 |
Li, J; Li, N; Pan, L; Wang, W; Wang, X; Zhang, F | 1 |
Banday, AA; Lokhandwala, MF | 1 |
Aoki, T; Atsumi, R; Itokawa, K; Iwasaki, M; Izumi, T; Okazaki, O; Ono, C; Shimizu, S; Sudo, K | 1 |
Chugh, G; Saha, K; Salim, S; Sarraj, N; Taneja, M; Tejada-Simon, MV | 1 |
de Mello, CF; de Oliveira Ferreira, AP; Ferreira, J; Rossato, MF; Velloso, NA | 1 |
Atsumi, R; Izumi, T; Nakazawa, T; Okazaki, O; Saji, H; Shimizu, S; Sudo, K | 1 |
Fukui, K; Ichiseki, T; Kaneuji, A; Matsumoto, T; Mikami, T; Nakagawa, S; Ueda, Y | 1 |
Aoyama, Y; Ishikawa, S; Izumi, T; Kishihara, J; Kosukegawa, T; Kurokawa, S; Masaki, Y; Niwano, H; Niwano, S | 1 |
Bertholet, L; Cabungcal, JH; Preissmann, D; Schenk, F; Sierro, G | 1 |
Asghar, M; Chugh, G; Hovatta, I; Salim, S; Taneja, M; Vollert, C; Vu, A | 1 |
Cherif, M; Elgaaied, AB; Hamden, K; Hamrita, B; Jaouadi, B; Kouidi, S; Medimegh, I; Messai, Y; Ouerhani, S; Rouissi, K | 1 |
Baca, Y; Pérez-Abud, R; Rodríguez-Gómez, I; Vargas Tendero, P; Vargas, F; Wangensteen, R | 1 |
Andreu, AL; Bianchi, P; Ferrer, I; Fourcade, S; Galino, J; López-Erauskin, J; Muñoz-Pinedo, C; Pujol, A | 1 |
Brenner, D; Grusdat, M; Harris, IS; Häussinger, D; Hengartner, H; Honke, N; Lang, E; Lang, KS; Lang, PA; Mak, TW; Maney, SK; McIlwain, DR; Odermatt, B; Ohashi, PS; Pandyra, AA; Pozdeev, VI; Recher, M; Shaabani, N; Xu, HC; Zinkernagel, RM | 1 |
Abukhalaf, IK; Bayorh, MA; Eatman, D; Ganafa, AA; Silvestrov, N; Socci, RR | 2 |
Hodgson, HJ; Rahman, TM; Selden, AC | 1 |
Chen, CF; Ho, LT; Lin, AM | 1 |
Antônio, MA; Bighetti, AE; Carvalho, JE; Rosaneli, CF; Sgarbieri, VC | 1 |
Gartung, C; Geier, A; Jansen, B; Matern, S; Purucker, E; Roeb, E; Winograd, R | 1 |
Castagné, V; Cuénod, M; Do, KQ | 1 |
Castagné, V; Cuenod, M; Do, KQ; Rougemont, M | 1 |
Barber, DS; Buzescu, R; Chopra, R; Ferrante, RJ; Fox, JH; Hersch, SM; Kazantsev, A; Norflus, F; Singh, B; Swindell, MK; Zucker, B | 1 |
Horii, I; Kawashima, A; Lu, Y; Zhong, L | 1 |
Ichiseki, T; Kaneuji, A; Katsuda, S; Kitamura, K; Matsumoto, T; Ueda, Y | 1 |
Chow, J; Huang, M; Lee, C; Lin, C; Lin, Y; Liu, C; Liu, HE | 1 |
Andersen, JK; Butterfield, DA; Chinta, SJ; Rajagopalan, S | 1 |
Cente, M; Filipcik, P; Novak, M; Pevalova, M | 1 |
Ichiseki, T; Kaneuji, A; Kitamura, K; Matsumoto, T; Sugimori, T | 1 |
Chen, X; Connors, SG; Mendonca, M; Patel, K; Welch, WJ; Wilcox, CS | 1 |
Kise, M; Mamiya, T; Morikawa, K | 1 |
Faúndez, M; Ferreira, J; Kemmerling, U; López-Muñoz, R; Maya, JD; Morello, A; Orellana, M; Torres, G | 1 |
Masood, A; Mustafa, SJ; Nadeem, A; O'Donnell, JM | 1 |
Li, Y; Trush, MA; Zhu, H | 1 |
Fujihara, Y; Iguchi, S; Kaneo, Y; Ogawa, K; Tanaka, T | 1 |
Adrian, TE; Bagchi, D; Hinder, RA; Kretchmar, DH; Perdikis, G; Redmond, EJ; Stinson, RG; Wetscher, GJ | 1 |
Gandolfi, AJ; Hall, PM; Lind, RC | 1 |
Hatano, T; Kojima, M | 1 |
Bengal, RJ; Litwiller, RD; Torres, VE; Wilson, DM | 1 |
Bowers, RR; Buckner, S; Gonzalez, Y; Nguyen, B; Ruiz, F | 1 |
Kawazoe, S; Mizutani, T; Murakami, M; Shirai, M; Yoshida, K | 1 |
Ji, LL; Leichtweis, S | 1 |
Kitamoto, K; Nagasawa, T; Soejima, A; Suzuki, M; Waku, M | 1 |
Broquist, HP | 1 |
Lewellyn, AL; Parchment, RE; Pierce, GB | 1 |
Fujii, K; Kitahara, S; Ohtsu, A | 1 |
Deeg, HJ; Luk, K; Shulman, HM; Shuman, WB; Storb, R | 1 |
Calvin, HI; Medvedovsky, C; Worgul, BV | 1 |
3 review(s) available for buthionine sulfoximine and Disease Models, Animal
Article | Year |
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Cardiovascular and renal manifestations of glutathione depletion induced by buthionine sulfoximine.
Topics: Animals; Antioxidants; Blood Pressure; Buthionine Sulfoximine; Cardiovascular System; Disease Models, Animal; Glutathione; Hypertension; Kidney; Mice; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2012 |
[Oxidative stress on idiopathic osteonecrosis].
Topics: Animals; Antioxidants; Buthionine Sulfoximine; Disease Models, Animal; Female; Glutathione; Humans; Osteonecrosis; Oxidative Stress; Rabbits; Rats; Rats, Wistar | 2007 |
Buthionine sulfoximine, an experimental tool to induce glutathione deficiency: elucidation of glutathione and ascorbate in their role as antioxidants.
Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Disease Models, Animal; Glutathione; Methionine Sulfoximine; Rats | 1992 |
68 other study(ies) available for buthionine sulfoximine and Disease Models, Animal
Article | Year |
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Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, Spinal; Humans; Mice, Inbred C57BL; Mice, Knockout; Neurons; Pruritus; Receptors, Atrial Natriuretic Factor; Reproducibility of Results; Signal Transduction; Small Molecule Libraries | 2019 |
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection | 2020 |
Human Wharton's Jelly-derived mesenchymal stem cells prevent acetaminophen-induced liver injury in a mouse model unlike human dermal fibroblasts.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Animal; Fibroblasts; Hepatocytes; Humans; Liver; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Wharton Jelly | 2022 |
The synergy of β amyloid 1-42 and oxidative stress in the development of Alzheimer's disease-like neurodegeneration of hippocampal cells.
Topics: Alzheimer Disease; Amyloid beta-Peptides; Animals; Antioxidants; Buthionine Sulfoximine; Disease Models, Animal; Hippocampus; Oxidative Stress; Peptide Fragments; Rats; Reactive Oxygen Species | 2022 |
Glutathione Deficiency and Alterations in the Sulfur Amino Acid Homeostasis during Early Postnatal Development as Potential Triggering Factors for Schizophrenia-Like Behavior in Adult Rats.
Topics: Amino Acids, Sulfur; Animals; Buthionine Sulfoximine; Disease Models, Animal; DNA Methylation; Glutathione; Homeostasis; Male; Piperazines; Rats; Rats, Sprague-Dawley; Schizophrenia | 2019 |
Taurine supplementation protects lens against glutathione depletion.
Topics: Animals; Buthionine Sulfoximine; Cataract; Dietary Supplements; Disease Models, Animal; Female; Glutathione; Humans; Lens, Crystalline; Male; Oxidative Stress; Rabbits; Taurine | 2021 |
The antioxidant glutathione protects against enteric neuron death in situ, but its depletion is protective during colitis.
Topics: Animals; Antioxidants; Buthionine Sulfoximine; Cell Death; Colitis; Colon; Dinitrofluorobenzene; Disease Models, Animal; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; In Vitro Techniques; Male; Mice, Inbred C57BL; Myenteric Plexus; Neuroglia; Neurons; Phenotype | 2018 |
Glutathione depletion: Starting point of brain metabolic stress, neuroinflammation and cognitive impairment in rats.
Topics: Animals; Avoidance Learning; Brain; Brain Diseases; Buthionine Sulfoximine; Cognitive Dysfunction; Disease Models, Animal; Glutathione; Inflammation; Male; Maze Learning; Oxidative Stress; Random Allocation; Rats, Sprague-Dawley; Reactive Oxygen Species; Spatial Memory; Tumor Necrosis Factor-alpha | 2018 |
Establishment of a drug-induced rhabdomyolysis mouse model by co-administration of ciprofloxacin and atorvastatin.
Topics: Acute Kidney Injury; Animals; Anti-Bacterial Agents; Aspartate Aminotransferases; Atorvastatin; Buthionine Sulfoximine; Ciprofloxacin; Creatine Kinase; Disease Models, Animal; Drug Interactions; Female; Glutathione Synthase; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Rhabdomyolysis | 2018 |
Acute kidney injury model established by systemic glutathione depletion in mice.
Topics: Acute Kidney Injury; Alanine Transaminase; Animals; Buthionine Sulfoximine; Disease Models, Animal; Glutathione; Liver; Male; Mice; Mice, Inbred C57BL; Muscle, Skeletal; Myoglobin | 2019 |
Grape powder supplementation prevents oxidative stress-induced anxiety-like behavior, memory impairment, and high blood pressure in rats.
Topics: Animals; Anxiety; Behavior, Animal; Brain Chemistry; Brain-Derived Neurotrophic Factor; Buthionine Sulfoximine; Calcium-Calmodulin-Dependent Protein Kinase Type 4; Cyclic AMP Response Element-Binding Protein; Dietary Supplements; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Food, Preserved; Freeze Drying; Fruit; Glutathione Reductase; Hypertension; Lactoylglutathione Lyase; Male; Memory Disorders; Oxidative Stress; Polyphenols; Rats; Rats, Sprague-Dawley; Vitis | 2013 |
A novel mouse model for phenytoin-induced liver injury: involvement of immune-related factors and P450-mediated metabolism.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Female; Glutathione; Immunity, Innate; Inflammasomes; Inflammation Mediators; Liver; Mice; Mice, Inbred C57BL; Necrosis; Oxidative Stress; Phenytoin; T-Lymphocytes, Helper-Inducer | 2013 |
Pharmacological prolyl hydroxylase domain inhibition as a therapeutic target for Parkinson's disease.
Topics: Age Factors; Analysis of Variance; Animals; Buthionine Sulfoximine; Cell Line, Transformed; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Glutathione; Hydroxybenzoates; Mass Spectrometry; Mice; Mice, Transgenic; Mitochondria; Oxygen Consumption; Parkinson Disease; Prolyl Hydroxylases; Prolyl-Hydroxylase Inhibitors; Rats; Substantia Nigra | 2014 |
Sex biased spatial strategies relying on the integration of multimodal cues in a rat model of schizophrenia: impairment in predicting future context?
Topics: Animals; Buthionine Sulfoximine; Cues; Disease Models, Animal; Female; Male; Maze Learning; Memory; Rats; Rats, Wistar; Schizophrenic Psychology; Sex Factors; Space Perception; Time Factors | 2014 |
Glutathione modulation during sensitization as well as challenge phase regulates airway reactivity and inflammation in mouse model of allergic asthma.
Topics: Animals; Antioxidants; Asthma; Buthionine Sulfoximine; Disease Models, Animal; Gene Expression Regulation, Enzymologic; Glutathione; Hypersensitivity; Inflammation; Lipid Peroxidation; Lung; Male; Mice; Mice, Inbred BALB C; NADPH Oxidases; Oxidants; Reactive Oxygen Species | 2014 |
Acute glutathione depletion leads to enhancement of airway reactivity and inflammation via p38MAPK-iNOS pathway in allergic mice.
Topics: Animals; Asthma; Bronchial Hyperreactivity; Buthionine Sulfoximine; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Inflammation; Male; Mice; Mice, Inbred BALB C; Nitric Oxide; Nitric Oxide Synthase Type II; Nitrosation; Oxidation-Reduction; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species; Signal Transduction | 2014 |
Evaluation of hepatic damage by reactive metabolites--with consideration of circadian variation of murine hepatic glutathione levels.
Topics: Acetaminophen; Administration, Oral; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Circadian Rhythm; Disease Models, Animal; Glutathione; Liver; Male; Mice, Inbred BALB C; Osmosis; Time Factors; Water | 2014 |
Vascular oxidative stress upregulates angiotensin II type I receptors via mechanisms involving nuclear factor kappa B.
Topics: Animals; Aorta; Buthionine Sulfoximine; Cells, Cultured; Disease Models, Animal; Humans; Hypertension; Muscle, Smooth, Vascular; NF-kappa B; Oxidants; Oxidative Stress; Proline; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Signal Transduction; Thiocarbamates; Up-Regulation; Vasoconstriction | 2014 |
Anxiety modulates cognitive deficits in a perinatal glutathione deficit animal model of schizophrenia.
Topics: Animals; Anxiety; Avoidance Learning; Behavior, Animal; Buthionine Sulfoximine; Cognitive Dysfunction; Disease Models, Animal; Glutathione; Locomotion; Male; Prepulse Inhibition; Rats; Rats, Wistar; Reflex, Startle; Schizophrenia; Schizophrenic Psychology | 2016 |
Psoriasis-like inflammation leads to renal dysfunction via upregulation of NADPH oxidases and inducible nitric oxide synthase.
Topics: Acetylcysteine; Aminoquinolines; Animals; Antioxidants; Buthionine Sulfoximine; Disease Models, Animal; Humans; Imiquimod; Inflammation; Kidney; Kidney Diseases; Male; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Nitric Oxide Synthase Type II; Oxidative Stress; Psoriasis | 2017 |
Establishment of a novel mouse model for pioglitazone-induced skeletal muscle injury.
Topics: Adenosine Triphosphate; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Creatine Kinase; Disease Models, Animal; Female; Glutathione; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred ICR; MicroRNAs; Muscle, Skeletal; Muscular Diseases; Pioglitazone; Thiazolidinediones | 2017 |
Effects of human Werner helicase on intrachromosomal homologous recombination mediated DNA deletions in mice.
Topics: 4-Nitroquinoline-1-oxide; Animals; Buthionine Sulfoximine; Disease Models, Animal; DNA; DNA Damage; DNA Repair; Exodeoxyribonucleases; Female; Genomic Instability; Glutathione; Humans; Mice; Mice, Inbred C57BL; Mice, Transgenic; Oxidative Stress; Pigment Epithelium of Eye; Pregnancy; Recombination, Genetic; RecQ Helicases; Sequence Deletion; Werner Syndrome; Werner Syndrome Helicase | 2008 |
Redox modulation at the peripheral site alters nociceptive transmission in vivo.
Topics: Alkylating Agents; Analgesics; Animals; Azoles; Behavior, Animal; Buthionine Sulfoximine; Disease Models, Animal; Dithiothreitol; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Iodoacetates; Isoindoles; Mice; Organoselenium Compounds; Oxidation-Reduction; Pain; Receptors, N-Methyl-D-Aspartate; Reducing Agents; Signal Transduction; Sulfhydryl Compounds | 2009 |
Glutamine attenuates lipopolysaccharide-induced acute lung injury.
Topics: Acute Lung Injury; Animals; Bronchoalveolar Lavage; Bronchoalveolar Lavage Fluid; Buthionine Sulfoximine; CD11b Antigen; CD18 Antigens; Disease Models, Animal; Glutamine; Glutathione; Inflammation; Interleukin-8; Lipopolysaccharides; Lung; Male; Neutrophils; Peroxidase; Random Allocation; Rats; Rats, Sprague-Dawley | 2009 |
Inhibition of natriuretic factors increases blood pressure in rats.
Topics: Amidohydrolases; Animals; Antioxidants; Arginine; Blood Pressure; Buthionine Sulfoximine; Cyclic N-Oxides; Disease Models, Animal; Dopamine; Hypertension; Kidney Tubules, Proximal; Male; Natriuresis; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidants; Oxidative Stress; Phosphorylation; Protein Kinase C; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Serine; Signal Transduction; Sodium Chloride, Dietary; Sodium-Potassium-Exchanging ATPase; Spin Labels | 2009 |
Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice.
Topics: Alanine Transaminase; Amodiaquine; Animals; Antimalarials; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Glutathione; Lethal Dose 50; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Models, Biological | 2009 |
Moderate treadmill exercise prevents oxidative stress-induced anxiety-like behavior in rats.
Topics: Adaptation, Ocular; Analysis of Variance; Animals; Anxiety; Brain; Buthionine Sulfoximine; Cyclic N-Oxides; Dinoprost; Disease Models, Animal; Drug Administration Schedule; Enzyme Inhibitors; Exercise Test; Exploratory Behavior; Glutathione; Male; Malondialdehyde; Neuroprotective Agents; Oxidative Stress; Physical Conditioning, Animal; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Spin Labels; Time Factors | 2010 |
Spinal levels of nonprotein thiols are related to nociception in mice.
Topics: Acetylcysteine; Acute Disease; Analgesics; Animals; Antimetabolites; Arthritis, Experimental; Behavior, Animal; Buthionine Sulfoximine; Capsaicin; Disease Models, Animal; Female; Foot Injuries; Lipid Peroxidation; Lumbar Vertebrae; Male; Mice; Oxidative Stress; Pain; Spinal Cord; Sulfhydryl Compounds | 2010 |
Ticlopidine-induced hepatotoxicity in a GSH-depleted rat model.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Glutathione; Platelet Aggregation Inhibitors; Protein Binding; Rats; Ticlopidine; Triazoles | 2011 |
Osteonecrosis development in a novel rat model characterized by a single application of oxidative stress.
Topics: Animals; Buthionine Sulfoximine; Disease Models, Animal; Glutathione; Liver; Male; Osteonecrosis; Oxidative Stress; Rats; Rats, Wistar | 2011 |
Progression of ventricular remodeling and arrhythmia in the primary hyperoxidative state of glutathione-depleted rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Action Potentials; Analysis of Variance; Animals; Arrhythmias, Cardiac; Blood Pressure; Blotting, Western; Buthionine Sulfoximine; Cardiac Pacing, Artificial; Cytokines; Deoxyguanosine; Disease Models, Animal; Disease Progression; Ether-A-Go-Go Potassium Channels; Glutathione; Hydrogen Peroxide; Immunohistochemistry; Myocardium; Natriuretic Peptide, Brain; Oxidative Stress; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Shal Potassium Channels; Time Factors; Ventricular Dysfunction; Ventricular Remodeling | 2011 |
Accurate performance of a rat model of schizophrenia in the water maze depends on visual cue availability and stability: a distortion in cognitive mapping abilities?
Topics: Animals; Buthionine Sulfoximine; Cognition; Cues; Disease Models, Animal; Drug Administration Schedule; Female; Male; Maze Learning; Photic Stimulation; Psychomotor Performance; Rats; Rats, Mutant Strains; Rats, Wistar; Schizophrenia; Schizophrenic Psychology; Space Perception | 2011 |
Potential contribution of oxidative stress and inflammation to anxiety and hypertension.
Topics: Analysis of Variance; Animals; Anxiety; Brain; Brain-Derived Neurotrophic Factor; Buthionine Sulfoximine; Calpain; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; Glutathione Reductase; Hypertension; Inflammation; Interleukin-6; Lactoylglutathione Lyase; Male; Oxidative Stress; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Signal Transduction; Time Factors; Tumor Necrosis Factor-alpha; Xanthine; Xanthine Oxidase | 2011 |
In vivo prevention of bladder urotoxicity: purified hydroxytyrosol ameliorates urotoxic effects of cyclophosphamide and buthionine sulfoximine in mice.
Topics: Animals; Antioxidants; Buthionine Sulfoximine; Catalase; Chromatography, Gas; Chromatography, High Pressure Liquid; Cyclophosphamide; Disease Models, Animal; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Industrial Waste; Lipid Peroxidation; Male; Mass Spectrometry; Mice; Olea; Phenylethyl Alcohol; Plant Extracts; Urinary Bladder; Urinary Bladder Diseases | 2011 |
Oxidative stress modulates mitochondrial failure and cyclophilin D function in X-linked adrenoleukodystrophy.
Topics: Acetylcysteine; Adenosine Triphosphate; Adrenoleukodystrophy; Age Factors; Analysis of Variance; Animals; ATP Binding Cassette Transporter 1; ATP-Binding Cassette Transporters; Brain; Buthionine Sulfoximine; Cell Death; Chromatin; Cyclophilins; Disease Models, Animal; Enzyme Inhibitors; Fibroblasts; Flow Cytometry; Galactose; Gene Expression Regulation; Glucose; Glutathione; Humans; Membrane Potential, Mitochondrial; Mice; Mice, Knockout; Microscopy, Electron, Transmission; Neuroprotective Agents; Oligopeptides; Oxidative Stress; Peptidyl-Prolyl Isomerase F; Permeability; Reactive Oxygen Species; Thioctic Acid; Time Factors; Tubulin; Vitamin E | 2012 |
Reactive oxygen species delay control of lymphocytic choriomeningitis virus.
Topics: Animals; Buthionine Sulfoximine; CD8-Positive T-Lymphocytes; Cell Survival; Cells, Cultured; Disease Models, Animal; Glutathione; Liver; Lymphocytic Choriomeningitis; Lymphocytic choriomeningitis virus; Mice; Mice, Inbred C57BL; Mice, Knockout; NADPH Oxidases; Reactive Oxygen Species; Spleen | 2013 |
Effect of palm oil on oxidative stress-induced hypertension in Sprague-Dawley rats.
Topics: Animals; Buthionine Sulfoximine; Computer Graphics; Disease Models, Animal; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Glutathione; Hypertension; Immunoenzyme Techniques; Isoprostanes; Nitric Oxide; Oxidative Stress; Palm Oil; Plant Oils; Rats; Rats, Sprague-Dawley; Thromboxane A2 | 2002 |
A novel model of acetaminophen-induced acute hepatic failure in rabbits.
Topics: Acetaminophen; Acute Disease; Animals; Antimetabolites; Buthionine Sulfoximine; Disease Models, Animal; Drug Synergism; Glutathione; Hepatic Encephalopathy; Injections, Intravenous; Injections, Subcutaneous; Liver; Liver Failure; Male; Methylcholanthrene; Phenobarbital; Rabbits | 2002 |
Neuroprotective effect of intermittent hypoxia on iron-induced oxidative injury in rat brain.
Topics: Animals; Atmosphere Exposure Chambers; Brain; Buthionine Sulfoximine; Catalase; Disease Models, Animal; Drug Administration Routes; Female; Glutathione; Glutathione Disulfide; Glutathione Peroxidase; Hypoxia; Iron; Parkinson Disease; Parkinson Disease, Secondary; Rats; Rats, Wistar; Substantia Nigra; Superoxide Dismutase | 2002 |
Efficacy of a whey protein concentrate on the inhibition of stomach ulcerative lesions caused by ethanol ingestion.
Topics: Administration, Oral; Animals; Anti-Ulcer Agents; Buthionine Sulfoximine; Carbenoxolone; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ethanol; Gastric Mucosa; Glutathione; Injections, Intraperitoneal; Injections, Subcutaneous; Male; Milk Proteins; Random Allocation; Rats; Rats, Wistar; Stomach Ulcer; Sulfhydryl Compounds; Treatment Outcome; Whey Proteins | 2002 |
Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Buthionine Sulfoximine; Cyclic AMP; Cyclic GMP; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; F2-Isoprostanes; Glutathione; Heart Rate; Hypertension; Kidney; Losartan; Male; Models, Cardiovascular; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Thromboxane A2; Treatment Outcome | 2003 |
Effect of glutathione depletion and hydrophilic bile acids on hepatic acute phase reaction in rats with extrahepatic cholestasis.
Topics: Acute-Phase Proteins; Acute-Phase Reaction; Animals; Bile Acids and Salts; Bile Ducts; Buthionine Sulfoximine; Cholestasis, Extrahepatic; Cytokines; Disease Models, Animal; Glutathione; Hydrophobic and Hydrophilic Interactions; Ligation; Liver; Male; Rats; Rats, Sprague-Dawley; RNA, Messenger | 2003 |
An animal model with relevance to schizophrenia: sex-dependent cognitive deficits in osteogenic disorder-Shionogi rats induced by glutathione synthesis and dopamine uptake inhibition during development.
Topics: Aging; Animals; Animals, Newborn; Behavior, Animal; Body Weight; Brain Chemistry; Buthionine Sulfoximine; Cognition Disorders; Disease Models, Animal; Dopamine; Dopamine Uptake Inhibitors; Embryonic and Fetal Development; Enzyme Inhibitors; Exploratory Behavior; Female; Glutathione; Lipid Peroxidation; Male; Maze Learning; Medulla Oblongata; Motor Activity; Pharmacy and Therapeutics Committee; Piperazines; Pons; Pregnancy; Psychomotor Performance; Rats; Rats, Mutant Strains; Recognition, Psychology; Schizophrenia; Sex Characteristics; Time Factors | 2004 |
Low brain glutathione and ascorbic acid associated with dopamine uptake inhibition during rat's development induce long-term cognitive deficit: relevance to schizophrenia.
Topics: Animals; Ascorbic Acid Deficiency; Body Weight; Brain; Brain Chemistry; Buthionine Sulfoximine; Cognition Disorders; Disease Models, Animal; Dopamine; Dopamine Plasma Membrane Transport Proteins; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Female; Glutathione; Male; Maze Learning; Membrane Proteins; Nerve Tissue Proteins; Neurons; Oxidative Stress; Piperazines; Rats; Rats, Mutant Strains; Rats, Wistar; Recognition, Psychology; Schizophrenia; Synaptic Transmission | 2004 |
Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation.
Topics: Animals; Antioxidants; Brain; Buthionine Sulfoximine; Cystamine; Cysteine; Cytoprotection; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Female; Gene Expression Regulation; Glutathione; Humans; Huntington Disease; Male; Mice; Mice, Transgenic; Neurons; Neuroprotective Agents; Oxidative Stress; PC12 Cells; Peptides; Rats | 2004 |
Cisplatin-induced cytotoxicity in BSO-exposed renal proximal tubular epithelial cells: sex, age, and species.
Topics: Animals; Buthionine Sulfoximine; Cell Death; Cell Survival; Cells, Cultured; Cisplatin; Disease Models, Animal; Epithelial Cells; Female; Haplorhini; Kidney Tubules, Proximal; Male; Rats; Rats, Sprague-Dawley; Sex Factors; Species Specificity | 2005 |
Oxidative stress by glutathione depletion induces osteonecrosis in rats.
Topics: Animals; Buthionine Sulfoximine; Disease Models, Animal; Enzyme Inhibitors; Female; Glutathione; Male; Osteonecrosis; Oxidative Stress; Rats; Rats, Wistar | 2006 |
Increased cellular glutathione and protection by bone marrow stromal cells account for the resistance of non-acute promylocytic leukemia acute myeloid leukemia cells to arsenic trioxide in vivo.
Topics: Acute Disease; Animals; Antineoplastic Agents; Arsenic Trioxide; Arsenicals; Bone Marrow Cells; Buthionine Sulfoximine; Cell Count; Cell Line, Tumor; Coculture Techniques; Disease Models, Animal; Drug Resistance, Neoplasm; Glutathione; Humans; Injections, Intraperitoneal; Leukemia, Myeloid; Mice; Mice, Inbred NOD; Mice, SCID; Oxides; Stromal Cells; Treatment Failure | 2006 |
In vitro and in vivo neuroprotection by gamma-glutamylcysteine ethyl ester against MPTP: relevance to the role of glutathione in Parkinson's disease.
Topics: Analysis of Variance; Animals; Buthionine Sulfoximine; Cell Line; Chromatography, High Pressure Liquid; Dipeptides; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Glutathione; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; MPTP Poisoning; Neuroprotective Agents; Rats; Tyrosine 3-Monooxygenase | 2006 |
Expression of a truncated tau protein induces oxidative stress in a rodent model of tauopathy.
Topics: Alzheimer Disease; Animals; Animals, Genetically Modified; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Cerebral Cortex; Disease Models, Animal; Enzyme Inhibitors; Glucose Oxidase; Humans; Mitochondria; Neurons; Oxidative Stress; Protein Isoforms; Rats; Reactive Oxygen Species; tau Proteins; Tauopathies | 2006 |
Acute antihypertensive action of Tempol in the spontaneously hypertensive rat.
Topics: Amitrole; Animals; Antihypertensive Agents; Blood Pressure; Buthionine Sulfoximine; Catalase; Cromakalim; Cyclic N-Oxides; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Ganglionic Blockers; Glutathione Peroxidase; Glyburide; Heart Rate; Heme Oxygenase (Decyclizing); Hexamethonium; Hypertension; Infusions, Intravenous; KATP Channels; Large-Conductance Calcium-Activated Potassium Channels; Male; Metalloporphyrins; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptides; Potassium Channel Blockers; Rats; Rats, Inbred SHR; Spin Labels; Sympathetic Nervous System; Time Factors | 2007 |
Ferulic acid attenuated cognitive deficits and increase in carbonyl proteins induced by buthionine-sulfoximine in mice.
Topics: Analysis of Variance; Animals; Behavior, Animal; Buthionine Sulfoximine; Cognition Disorders; Coumaric Acids; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Exploratory Behavior; Free Radical Scavengers; Male; Maze Learning; Mice; Mice, Inbred ICR; Protein Carbonylation | 2008 |
Buthionine sulfoximine has anti-Trypanosoma cruzi activity in a murine model of acute Chagas' disease and enhances the efficacy of nifurtimox.
Topics: Acute Disease; Animals; Buthionine Sulfoximine; Chagas Disease; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Mice; Mice, Inbred BALB C; Nifurtimox; Survival Rate; Trypanocidal Agents; Trypanosoma cruzi | 2008 |
Reversal of oxidative stress-induced anxiety by inhibition of phosphodiesterase-2 in mice.
Topics: Animals; Antioxidants; Anxiety; Behavior, Animal; Buthionine Sulfoximine; Cells, Cultured; Cerebral Cortex; Cyclic GMP; Cyclic Nucleotide Phosphodiesterases, Type 2; Disease Models, Animal; Lipid Peroxides; Male; Maze Learning; Mice; Mice, Inbred ICR; NADPH Oxidases; Neurons; Oxidative Stress; Phosphodiesterase Inhibitors; Phosphorylation; Rats; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction | 2008 |
Characterization of benzo[a]pyrene quinone-induced toxicity to primary cultured bone marrow stromal cells from DBA/2 mice: potential role of mitochondrial dysfunction.
Topics: Adenosine Triphosphate; Anemia, Aplastic; Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Benzo(a)pyrene; Benzopyrenes; Bone Marrow; Bone Marrow Cells; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Dicumarol; Disease Models, Animal; Dose-Response Relationship, Drug; Glutathione; Leukemia, Experimental; Male; Methionine Sulfoximine; Mice; Mice, Inbred DBA; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Quinones; Stromal Cells; Superoxide Dismutase; Thiones; Thiophenes | 1995 |
A protective effect of glutathione-dextran macromolecular conjugates on acetaminophen-induced hepatotoxicity dependent on molecular size.
Topics: Acetaminophen; Animals; Antimetabolites; Aspartate Aminotransferases; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, Gel; Chromatography, High Pressure Liquid; Cyanogen Bromide; Delayed-Action Preparations; Dextrans; Disease Models, Animal; Drug Delivery Systems; Glutathione; In Vitro Techniques; Injections, Intravenous; Liver; Liver Diseases; Male; Methionine Sulfoximine; Mice; Molecular Weight; Survival Rate | 1994 |
Esophagitis in Sprague-Dawley rats is mediated by free radicals.
Topics: Animals; Buthionine Sulfoximine; Disease Models, Animal; Drug Evaluation, Preclinical; Esophagitis, Peptic; Esophagus; Free Radical Scavengers; Free Radicals; Glutamate-Cysteine Ligase; Glutathione; Linear Models; Male; Methionine Sulfoximine; Mucous Membrane; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Superoxide Dismutase; Time Factors | 1995 |
A model for fatal halothane hepatitis in the guinea pig.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutathione; Guinea Pigs; Halothane; Liver; Male; Methionine Sulfoximine; Necrosis | 1994 |
UV-b-induced cataract model in brown-Norway rat eyes combined with preadministration of buthionine sulfoximine.
Topics: Animals; Buthionine Sulfoximine; Cataract; Disease Models, Animal; Glutathione; Image Processing, Computer-Assisted; Lens, Crystalline; Light; Male; Radiation Injuries, Experimental; Radiation-Sensitizing Agents; Rats; Rats, Inbred BN; Scattering, Radiation; Ultraviolet Rays | 1996 |
Aggravation of polycystic kidney disease in Han:SPRD rats by buthionine sulfoximine.
Topics: Animals; Buthionine Sulfoximine; Disease Models, Animal; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione; Kidney; Male; Oxidation-Reduction; Polycystic Kidney, Autosomal Dominant; Rats; Rats, Mutant Strains | 1997 |
Role of antioxidants in the survival of normal and vitiliginous avian melanocytes.
Topics: Animals; Antioxidants; Buthionine Sulfoximine; Cell Survival; Chickens; Disease Models, Animal; Feathers; Ferrous Compounds; Genotype; Glutathione; Humans; Hydroxyl Radical; Melanocytes; Models, Biological; Oxidation-Reduction; Oxidative Stress; Pigmentation; Reactive Oxygen Species; Superoxide Dismutase; Superoxides; Vitiligo | 1999 |
Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutathione; Liver; Male; Methimazole; Mice; Mice, Inbred ICR; Necrosis; Structure-Activity Relationship; Thiourea | 2000 |
Glutathione deficiency intensifies ischaemia-reperfusion induced cardiac dysfunction and oxidative stress.
Topics: Animals; Buthionine Sulfoximine; Disease Models, Animal; Drug Therapy, Combination; Female; Glutathione; Heart; Isoxazoles; Liver; Mitochondria, Heart; Myocardial Contraction; Myocardial Reperfusion Injury; Myocardial Stunning; Myocardium; Oxidative Stress; Rats; Rats, Sprague-Dawley; Ventricular Function | 2001 |
[Alterations in phosphatidylcholine and phospholipase A2 of the renal tissue in gentamicin nephrotoxicity: comparative study with buthionine sulfoximine administered model].
Topics: Acute Kidney Injury; Animals; Buthionine Sulfoximine; Disease Models, Animal; Gentamicins; Glutathione; Kidney; Lipid Peroxidation; Male; Methionine Sulfoximine; Phosphatidylcholines; Phospholipases A; Phospholipases A2; Rats; Rats, Sprague-Dawley | 1992 |
Hydrogen peroxide as a mediator of programmed cell death in the blastocyst.
Topics: Animals; Antimetabolites; Blastocyst; Buthionine Sulfoximine; Catalase; Cell Survival; Disease Models, Animal; Glutathione; Hydrogen Peroxide; In Vitro Techniques; Methionine Sulfoximine; Mice; Neoplasms, Germ Cell and Embryonal; Tumor Cells, Cultured | 1991 |
Anticataractogenic property of gamma-glutamylcysteine ethyl ester in an animal model of cataract.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cataract; Dipeptides; Disease Models, Animal; Glutathione; Kidney; Lens, Crystalline; Liver; Male; Methionine Sulfoximine; Organ Culture Techniques; Rats; Rats, Inbred Strains | 1991 |
Induction of hepatic veno-occlusive disease in dogs.
Topics: Animals; Busulfan; Buthionine Sulfoximine; Cyclophosphamide; Disease Models, Animal; Dog Diseases; Dogs; Hepatic Veno-Occlusive Disease; Liver; Melphalan; Methionine Sulfoximine; Methotrexate; Monocrotaline; Pyrrolizidine Alkaloids; Radiation Injuries, Experimental; Radiography | 1987 |
Near-total glutathione depletion and age-specific cataracts induced by buthionine sulfoximine in mice.
Topics: Age Factors; Animals; Buthionine Sulfoximine; Cataract; Disease Models, Animal; Glutathione; Humans; Kidney; Lens, Crystalline; Liver; Male; Methionine Sulfoximine; Mice; Testis | 1986 |