Page last updated: 2024-08-22

buthionine sulfoximine and Colonic Neoplasms

buthionine sulfoximine has been researched along with Colonic Neoplasms in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19908 (25.81)18.7374
1990's13 (41.94)18.2507
2000's5 (16.13)29.6817
2010's4 (12.90)24.3611
2020's1 (3.23)2.80

Authors

AuthorsStudies
Collin, A; Kohan, R; Picotto, G; Tolosa de Talamoni, N1
Ariga, T; Hasegawa, I; Hosono, T; Hosono-Fukao, T; Iitsuka, Y; Inada, K; Seki, T; Tanaka, R; Yamada, H1
Alonso-Varona, A; Caramés, M; García-Alonso, I; Palomares, T2
Iyamu, EW1
Cai, DQ; Kim, DH; Kim, SK; Lee, KJ; Qi, XF; Shim, KY; Teng, YC; Yoon, YS1
Cuevas, EP; Díaz-Laviada, I; Fernández-Moreno, MD; Gisbert, JP; Guijarro, LG; Hernández-Breijo, B; Monserrat, J; Ramírez-Rubio, S; Román, ID; Vara, D1
Armstrong, JS; Ming, SH; Moore, PK; Nam, OC; Rose, P; Whiteman, M1
Albino, AP; Komninou, D; Richie, JP1
Chow, S; Hedley, DW1
Berger, NA; Berger, SJ; Gosky, D; Willson, JK; Zborowska, E1
Lee, JH; Naito, M; Tsuruo, T1
Begg, AC; Los, G; Oldenburg, J; Pinedo, HM; Ruevekamp, M; Schornagel, JH; van Vugt, MJ1
Balasubramanian, KA; Benard, O1
Dimitriadis, KA; Geromichalos, GD; Kortsaris, AH; Kouretas, D; Papazisis, KT; Sivridis, E; Tsekreli, OK1
Borud, O; Huseby, NE; Leroy, P; Mikkelsen, IM; Mortensen, B; Wellman, M1
Chao, CC; Chou, WY; Huang, YT; Lin-Chao, S; Ma, CM1
Barranco, SC; Greaves, BR; Perry, RR; Rasberry, U1
Bruno, NA; Rabier, MJ; Slate, DL1
Alvarez, MG; Bates, SE; Fojo, AT; Lai, GM; Moscow, JA1
Gipp, JJ; McClelland, RA; Mulcahy, RT1
Fram, RJ; Robichaud, NJ1
Boyce, HW; Chen, LT; Chen, MF; Ying, HS1
Inaba, M; Iwata, K; Kubodera, A; Ozawa, S1
Gipp, JJ; McClelland, RA; Mulcahy, RT; Panicucci, R; Ublacker, GA1
Dikdan, G; Dimaira, MJ; Hu, JJ; Lea, MA; Zirvi, KA1
Leith, JT1
Arundel, CM; Bliven, SF; Hallows, KT; Leith, JT1
Cohen, GM; d'Arcy Doherty, M; Jordan, J1
Cordeiro, RF; Savarese, TM1
Guichard, M; Lespinasse, F; Malaise, EP1

Other Studies

31 other study(ies) available for buthionine sulfoximine and Colonic Neoplasms

ArticleYear
Melatonin Enhances Anti-tumoral Effects of Menadione on Colon Cancer Cells.
    Anti-cancer agents in medicinal chemistry, 2022, Volume: 22, Issue:13

    Topics: Antioxidants; Buthionine Sulfoximine; Caco-2 Cells; Colonic Neoplasms; Humans; Melatonin; Oxidative Stress; Vitamin K 3

2022
Alkenyl group is responsible for the disruption of microtubule network formation in human colon cancer cell line HT-29 cells.
    Carcinogenesis, 2008, Volume: 29, Issue:7

    Topics: Adenocarcinoma; Alkenes; Allyl Compounds; Buthionine Sulfoximine; Cell Division; Colonic Neoplasms; Cysteine; Disulfides; Drug Interactions; G2 Phase; Glutathione; HT29 Cells; Humans; Microtubules; Mitosis; Spindle Apparatus; Sulfides

2008
Glutathione modulation reverses the growth-promoting effect of growth factors, improving the 5-fluorouracil antitumour response in WiDr colon cancer cells.
    Anticancer research, 2009, Volume: 29, Issue:10

    Topics: Buthionine Sulfoximine; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Epidermal Growth Factor; Fluorouracil; Glutathione; Hepatocyte Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Pyrrolidonecarboxylic Acid; Thiazolidines; Vascular Endothelial Growth Factor A

2009
The redox state of the glutathione/glutathione disulfide couple mediates intracellular arginase activation in HCT-116 colon cancer cells.
    Digestive diseases and sciences, 2010, Volume: 55, Issue:9

    Topics: Arginase; Buthionine Sulfoximine; Colonic Neoplasms; Diamide; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Glutathione Disulfide; HCT116 Cells; Humans; Oxidants; Oxidation-Reduction; Oxidative Stress; Time Factors; Tumor Necrosis Factor-alpha

2010
Glutathione modulators reverse the pro-tumour effect of growth factors enhancing WiDr cell response to chemotherapeutic agents.
    Anticancer research, 2010, Volume: 30, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Camptothecin; Cell Growth Processes; Cell Line, Tumor; Colonic Neoplasms; Drug Synergism; Epidermal Growth Factor; Fluorouracil; Glutathione; Hepatocyte Growth Factor; Humans; Intercellular Signaling Peptides and Proteins; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Pyrrolidonecarboxylic Acid; Thiazolidines; Vascular Endothelial Growth Factor A

2010
Involvement of oxidative stress in simvastatin-induced apoptosis of murine CT26 colon carcinoma cells.
    Toxicology letters, 2010, Dec-15, Volume: 199, Issue:3

    Topics: Acetylcysteine; Animals; Apoptosis; Buthionine Sulfoximine; Cell Line, Tumor; Colonic Neoplasms; Glutathione; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Oligopeptides; Oxidative Stress; Polyisoprenyl Phosphates; Proto-Oncogene Proteins c-akt; Reactive Oxygen Species; Simvastatin

2010
Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma.
    World journal of gastroenterology, 2011, Sep-14, Volume: 17, Issue:34

    Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azathioprine; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cattle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Therapy, Combination; Humans; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation

2011
Hydrogen sulfide protects colon cancer cells from chemopreventative agent beta-phenylethyl isothiocyanate induced apoptosis.
    World journal of gastroenterology, 2005, Jul-14, Volume: 11, Issue:26

    Topics: Anticarcinogenic Agents; Apoptosis; Buthionine Sulfoximine; Cell Line, Tumor; Colonic Neoplasms; Humans; Hydrogen Sulfide; Isocyanates

2005
Induction of colon tumorigenesis by glutathione depletion in p53-knock-out mice.
    International journal of oncology, 2007, Volume: 30, Issue:6

    Topics: Animals; Buthionine Sulfoximine; Colonic Neoplasms; Enzyme Inhibitors; Glutathione; Male; Mice; Mice, Knockout; Tumor Suppressor Protein p53

2007
Evaluation of methods for measuring cellular glutathione content using flow cytometry.
    Cytometry, 1994, Apr-01, Volume: 15, Issue:4

    Topics: Animals; Breast Neoplasms; Bridged Bicyclo Compounds; Buthionine Sulfoximine; Carcinoma; Carcinosarcoma; CHO Cells; Colonic Neoplasms; Cricetinae; Ethylmaleimide; Eukaryotic Cells; Evaluation Studies as Topic; Flow Cytometry; Fluoresceins; Fluorescent Dyes; Glutathione; Humans; Maleates; Mammary Neoplasms, Experimental; Methionine Sulfoximine; Mice; o-Phthalaldehyde; Phenylmercury Compounds; Pyrazoles; Species Specificity; Tumor Cells, Cultured; Urinary Bladder Neoplasms

1994
Sensitive enzymatic cycling assay for glutathione: measurements of glutathione content and its modulation by buthionine sulfoximine in vivo and in vitro in human colon cancer.
    Cancer research, 1994, Aug-01, Volume: 54, Issue:15

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Colonic Neoplasms; Female; Glutathione; Humans; Kidney; Liver; Methionine Sulfoximine; Mice; Mice, Inbred C57BL; Mice, Nude; Rats; Rats, Sprague-Dawley; Reference Values; Transplantation, Heterologous; Tumor Cells, Cultured

1994
Nonenzymatic reductive activation of 7-N-((2-([2-(gamma-L-glutamylamino)ethyl]dithio)ethyl))mitomycin C by thiol molecules: a novel mitomycin C derivative effective on mitomycin C-resistant tumor cells.
    Cancer research, 1994, May-01, Volume: 54, Issue:9

    Topics: Buthionine Sulfoximine; Colonic Neoplasms; Cysteine; Cytochrome P-450 Enzyme System; DNA, Neoplasm; Drug Interactions; Drug Resistance; Glutathione; Humans; Methionine Sulfoximine; Mitomycin; Mitomycins; Oxidation-Reduction; Sulfhydryl Compounds; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
Characterization of resistance mechanisms to cis-diamminedichloroplatinum(II) in three sublines of the CC531 colon adenocarcinoma cell line in vitro.
    Cancer research, 1994, Jan-15, Volume: 54, Issue:2

    Topics: Adenocarcinoma; Animals; Buthionine Sulfoximine; Cisplatin; Colonic Neoplasms; DNA, Neoplasm; Drug Resistance; Glutathione; Methionine Sulfoximine; Methylazoxymethanol Acetate; Rats; Tumor Cells, Cultured; Tumor Stem Cell Assay

1994
Modulation of glutathione level during butyrate-induced differentiation in human colon derived HT-29 cells.
    Molecular and cellular biochemistry, 1997, Volume: 170, Issue:1-2

    Topics: Alkaline Phosphatase; Buthionine Sulfoximine; Butyrates; Butyric Acid; Cell Differentiation; Cell Division; Cell Line; Colon; Colonic Neoplasms; Glutathione; Humans; Kinetics; Time Factors; Tumor Cells, Cultured

1997
Effects of melatonin on proliferation of cancer cell lines.
    Journal of pineal research, 1998, Volume: 25, Issue:4

    Topics: Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Survival; Colonic Neoplasms; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Ethacrynic Acid; Female; Glutathione; Humans; Melatonin; Ovarian Neoplasms; Tumor Cells, Cultured; Uterine Cervical Neoplasms

1998
Regulation of gamma-glutamyltransferase in cisplatin-resistant and -sensitive colon carcinoma cells after acute cisplatin and oxidative stress exposures.
    International journal of cancer, 2000, Nov-01, Volume: 88, Issue:3

    Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cisplatin; Colonic Neoplasms; Drug Resistance, Neoplasm; gamma-Glutamyltransferase; Glutathione; Humans; Oxidative Stress; Reactive Oxygen Species; Tumor Cells, Cultured

2000
Overexpression of glutathione S-transferase and elevation of thiol pools in a multidrug-resistant human colon cancer cell line.
    Molecular pharmacology, 1992, Volume: 41, Issue:1

    Topics: Antimetabolites, Antineoplastic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Colonic Neoplasms; Doxorubicin; Drug Resistance; Gene Expression; Glutathione; Glutathione Transferase; HeLa Cells; Humans; Membrane Glycoproteins; Membrane Proteins; Methionine Sulfoximine; Neoplasm Proteins; Phenotype; Sulfhydryl Compounds; Transcription, Genetic; Tumor Cells, Cultured

1992
Effect of treatment duration and glutathione depletion on mitomycin C cytotoxicity in vitro.
    Cancer research, 1992, Sep-01, Volume: 52, Issue:17

    Topics: Buthionine Sulfoximine; Cell Survival; Colonic Neoplasms; Dose-Response Relationship, Drug; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Mitomycin; Tumor Cells, Cultured

1992
Multifactorial resistance in LS174T human colon carcinoma cells selected with doxorubicin.
    International journal of cancer, 1991, Oct-21, Volume: 49, Issue:4

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Division; Cell Line; Colonic Neoplasms; Doxorubicin; Drug Resistance; Flow Cytometry; Genetic Variation; Humans; Membrane Glycoproteins; Methionine Sulfoximine; Neoplasm Proteins

1991
Contribution of glutathione and glutathione-dependent enzymes in the reversal of adriamycin resistance in colon carcinoma cell lines.
    International journal of cancer, 1991, Nov-11, Volume: 49, Issue:5

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Division; Cell Survival; Colonic Neoplasms; Doxorubicin; Drug Resistance; Gene Expression; Glutathione; Glutathione Peroxidase; Glutathione Transferase; Humans; Membrane Glycoproteins; Methionine Sulfoximine; RNA, Messenger; Tumor Cells, Cultured; Verapamil

1991
DNA damage induced in HT-29 colon cancer cells by exposure to 1-methyl-2-nitrosoimidazole, a reductive metabolite of 1-methyl-2-nitroimidazole.
    Biochemical pharmacology, 1991, Dec-11, Volume: 42 Suppl

    Topics: Buthionine Sulfoximine; Colonic Neoplasms; DNA; DNA Damage; DNA, Neoplasm; Endopeptidase K; Humans; Hydrogen-Ion Concentration; Imidazoles; Methionine Sulfoximine; Nitroimidazoles; Nitroso Compounds; Oxidation-Reduction; Serine Endopeptidases; Tumor Cells, Cultured

1991
Schedule dependence of buthionine sulfoximine in reversing resistance to cisplatin.
    Chemico-biological interactions, 1990, Volume: 76, Issue:3

    Topics: Antimetabolites; Buthionine Sulfoximine; Cell Transformation, Neoplastic; Cisplatin; Colonic Neoplasms; Cross-Linking Reagents; DNA; Drug Resistance; Glutathione; Humans; Methionine Sulfoximine; Tumor Cells, Cultured

1990
Effect of DL-buthionine-S,R-sulfoximine on 1,2-dimethyl-hydrazine-induced colonic tumors in rats.
    Cancer letters, 1990, Volume: 49, Issue:3

    Topics: 1,2-Dimethylhydrazine; Animals; Bile Acids and Salts; Buthionine Sulfoximine; Carcinogens; Colonic Neoplasms; Dimethylhydrazines; Glutathione; Intestinal Mucosa; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains

1990
Intracellular glutathione levels in human colon cancer cells naturally resistant to cross-linking agents.
    Journal of pharmacobio-dynamics, 1989, Volume: 12, Issue:7

    Topics: Antimetabolites; Buthionine Sulfoximine; Cisplatin; Colonic Neoplasms; Cross-Linking Reagents; Drug Resistance; Glutathione; Humans; Leukemia; Methionine Sulfoximine; Nimustine; Tumor Cells, Cultured

1989
Cytotoxicity and glutathione depletion by 1-methyl-2-nitrosoimidazole in human colon cancer cells.
    Biochemical pharmacology, 1989, May-15, Volume: 38, Issue:10

    Topics: Buthionine Sulfoximine; Cell Survival; Colonic Neoplasms; Glutathione; Humans; Methionine Sulfoximine; Nitroimidazoles; Tumor Cells, Cultured

1989
Influence of pH on the modification of thiols by carbamoylating agents and effects on glutathione levels in normal and neoplastic cells.
    Cancer chemotherapy and pharmacology, 1989, Volume: 24, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Carbamates; Colonic Neoplasms; Cyanates; DNA, Neoplasm; Glutathione; Humans; Hydrogen-Ion Concentration; Kinetics; Liver; Liver Neoplasms, Experimental; Methionine Sulfoximine; Protein Biosynthesis; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Tumor Cells, Cultured

1989
Potentiation of X ray sensitivity by combinations of sodium butyrate and buthionine sulfoximine.
    International journal of radiation oncology, biology, physics, 1988, Volume: 15, Issue:4

    Topics: Buthionine Sulfoximine; Butyrates; Butyric Acid; Cell Line; Cell Survival; Colonic Neoplasms; Combined Modality Therapy; Drug Synergism; Humans; In Vitro Techniques; Methionine Sulfoximine; Radiation-Sensitizing Agents

1988
Changes in X-ray sensitivity and glutathione content of human colon tumor cells after exposure to the differentiation-inducing agent sodium butyrate.
    Radiation research, 1988, Volume: 114, Issue:3

    Topics: Buthionine Sulfoximine; Butyrates; Butyric Acid; Cell Line; Cell Survival; Colonic Neoplasms; DNA Repair; DNA, Neoplasm; Glutathione; Humans; Methionine Sulfoximine; Radiation Tolerance; Tumor Cells, Cultured

1988
Effects of glutathione depletion on the cytotoxicity of agents toward a human colonic tumour cell line.
    British journal of cancer, 1987, Volume: 55, Issue:6

    Topics: Antimetabolites; Antineoplastic Agents, Phytogenic; Buthionine Sulfoximine; Cell Line; Cell Survival; Colonic Neoplasms; Drug Evaluation, Preclinical; Glutathione; Humans; Melphalan; Methionine Sulfoximine; Naphthols; Naphthoquinones; Sesquiterpenes; Sesquiterpenes, Guaiane; Vitamin K

1987
Role of glutathione depletion in the mechanism of action of N-methylformamide and N,N-dimethylformamide in a cultured human colon carcinoma cell line.
    Cancer research, 1986, Volume: 46, Issue:3

    Topics: Buthionine Sulfoximine; Cell Cycle; Cell Line; Cisplatin; Colonic Neoplasms; Cysteine; Dimethylformamide; Dose-Response Relationship, Drug; Formamides; Glutathione; Humans; Methionine Sulfoximine; Solvents

1986
Influence of buthionine sulfoximine and misonidazole on glutathione level and radiosensitivity of human tumor xenografts.
    Radiation research, 1986, Volume: 105, Issue:1

    Topics: Adenocarcinoma; Animals; Buthionine Sulfoximine; Cell Line; Colonic Neoplasms; Female; Glutathione; Humans; Melanoma; Methionine Sulfoximine; Mice; Mice, Nude; Misonidazole; Neoplasm Transplantation; Neoplasms; Radiation Tolerance; Transplantation, Heterologous

1986