buthionine sulfoximine has been researched along with Carcinoma, Hepatocellular in 23 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (13.04) | 18.2507 |
| 2000's | 16 (69.57) | 29.6817 |
| 2010's | 4 (17.39) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, Y; Cho, EJ; Cho, H; Cho, YY; Jo, A; Kim, JB; Kim, YJ; Lee, JH; Lee, M; Lee, S; Nam, JY; Yoon, JH; Yu, SJ | 1 |
| Ji, L; Jiang, P; Morahan, G; Shen, K; Wang, Z | 1 |
| Cuevas, EP; Díaz-Laviada, I; Fernández-Moreno, MD; Gisbert, JP; Guijarro, LG; Hernández-Breijo, B; Monserrat, J; Ramírez-Rubio, S; Román, ID; Vara, D | 1 |
| Angulo, C; Barra, V; Cárcamo, JG; Concha, II; Escobar, D; González, M; Maldonado, M; Mardones, L; Mendoza, P; Oñate, G; Ormazabal, V; Reyes, AM; Rivas, CI; Sotomayor, K; Vera, JC; Villagrán, M; Zúñiga, FA | 1 |
| Huang, M; Jin, J; Liu, GT; Wei, HL | 1 |
| Lim, BG; Ng, KH; Wong, KP | 1 |
| Bolle, F; Dierickx, PJ; Elskens, M; Smet, PW | 1 |
| Barelli, D; Cantoni, L; Castell, JV; Hauri, L; Mangolini, A; Ponsoda, X; Rizzardini, M; Valaperta, R; Villa, P | 1 |
| Cederbaum, AI; Pérez, MJ | 1 |
| Chipman, JK; Spence, FJ; White, AT | 1 |
| Lin, T; Yang, MS | 1 |
| Cederbaum, A; Lu, Y | 1 |
| Bergelson, S; Daniel, V; Pinkus, R | 1 |
| Kim, HS; Kim, IK; Lee, JH | 1 |
| Cederbaum, AI; Marí, M | 1 |
| Liu, J; Ong, C; Shen, H; Yang, C | 1 |
| Chen, C; Chen, L; Huang, ZZ; Lu, SC; Oh, J; Yang, H; Zeng, Z | 1 |
| Andou, A; Hirai, R; Inoue, Y; Miyazaki, M; Namba, M; Nozaki, I; Sakaguchi, M; Shimizu, N; Tsuji, T | 1 |
| Chew, M; Mack, P; Wong, KP; Yang, EB; Zhang, K | 1 |
| Bäumer, AT; Hescheler, J; Ling, FC; Petrat, K; Sauer, H; Schallenberg, M; Wartenberg, M | 1 |
| Bai, J; Cederbaum, AI; Marí, M | 1 |
| Akao, Y; Kito, M; Nozawa, Y; Ohishi, N; Yagi, K | 1 |
| Dierickx, PJ | 1 |
23 other study(ies) available for buthionine sulfoximine and Carcinoma, Hepatocellular
| Article | Year |
|---|---|
3-bromopyruvate and buthionine sulfoximine effectively kill anoikis-resistant hepatocellular carcinoma cells.
Topics: Anoikis; Antineoplastic Agents; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Epithelial-Mesenchymal Transition; Hep G2 Cells; Humans; Liver Neoplasms; Niacinamide; Phenylurea Compounds; Pyruvates; Reactive Oxygen Species; Sorafenib | 2017 |
Critical roles of cellular glutathione homeostasis and jnk activation in andrographolide-mediated apoptotic cell death in human hepatoma cells.
Topics: Andrographis; Animals; Anti-Inflammatory Agents; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Apoptosis; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Diterpenes; Glutathione; Hep G2 Cells; Humans; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; Male; Mice; Mice, Nude | 2011 |
Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma.
Topics: Animals; Antimetabolites, Antineoplastic; Apoptosis; Azathioprine; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cattle; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Therapy, Combination; Humans; Liver Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation | 2011 |
Essential role of intracellular glutathione in controlling ascorbic acid transporter expression and function in rat hepatocytes and hepatoma cells.
Topics: Animals; Ascorbic Acid; Base Sequence; Buthionine Sulfoximine; Carcinoma, Hepatocellular; DNA Primers; Glutathione; Hepatocytes; Humans; Immunohistochemistry; Liver Neoplasms; Rats; Rats, Sprague-Dawley; Sodium-Coupled Vitamin C Transporters | 2012 |
Mechanism of 5-fluorouracil required resistance in human hepatocellular carcinoma cell line Bel(7402).
Topics: Buthionine Sulfoximine; Carcinoma, Hepatocellular; Drug Resistance, Neoplasm; Fluorescein; Fluorouracil; Glutathione; Glutathione Transferase; Humans; Liver Neoplasms; Multidrug Resistance-Associated Proteins; Thymidylate Synthase; Tumor Cells, Cultured | 2002 |
Sulfate conjugating and transport functions of MDCK distal tubular cells.
Topics: Animals; Biological Transport; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclosporine; Glutathione; Harmine; Humans; Immunosuppressive Agents; Kidney Tubules, Distal; Leukotriene Antagonists; Liver; Membrane Transport Proteins; Methotrexate; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Organic Anion Transport Protein 1; Probenecid; Propionates; Quinolines; Radiation-Protective Agents; Radiation-Sensitizing Agents; Sulfates; Uricosuric Agents | 2003 |
The role of oxidative stress on the effect of 1,4,7,10,13,16-hexathiacyclooctadecane on copper and zinc toxicity in HepG2 cells.
Topics: Buthionine Sulfoximine; Carcinoma, Hepatocellular; Copper; Dose-Response Relationship, Drug; Drug Combinations; Glutathione; Hepatocytes; Heterocyclic Compounds, 1-Ring; Humans; Oxidative Stress; Reactive Oxygen Species; Spectrophotometry, Atomic; Sulfides; Tumor Cells, Cultured; Zinc | 2003 |
Induction of hepatic heme oxygenase-1 by diclofenac in rodents: role of oxidative stress and cytochrome P-450 activity.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diclofenac; Dose-Response Relationship, Drug; Enzyme Induction; Enzyme Inhibitors; Female; Heme Oxygenase (Decyclizing); Heme Oxygenase-1; Hepatocytes; Humans; Liver; Liver Neoplasms; Male; Membrane Proteins; Mice; Mice, Inbred Strains; Oxidative Stress; Rats | 2003 |
Proteasome inhibition potentiates CYP2E1-mediated toxicity in HepG2 cells.
Topics: Antioxidants; Arachidonic Acid; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cysteine Endopeptidases; Cytochrome P-450 CYP2E1; Drug Synergism; Endopeptidases; Humans; Iron; Leupeptins; Lipid Peroxides; Liver Neoplasms; Lysosomes; Membrane Potentials; Mitochondria, Liver; Multienzyme Complexes; Proteasome Endopeptidase Complex; Tumor Cells, Cultured; Tyrosine | 2003 |
Glutathione depletion modulates gene expression in HepG2 cells via activation of protein kinase C alpha.
Topics: Animals; Apoptosis; Blotting, Western; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; Enzyme Activation; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Glutathione; Humans; L-Lactate Dehydrogenase; Liver Neoplasms; Oligonucleotide Array Sequence Analysis; Phosphorylation; Protein Isoforms; Protein Kinase C; Protein Kinase C-alpha; Protein Transport; Reverse Transcriptase Polymerase Chain Reaction; Time Factors | 2005 |
Benzo[a]pyrene-induced elevation of GSH level protects against oxidative stress and enhances xenobiotic detoxification in human HepG2 cells.
Topics: Aryl Hydrocarbon Hydroxylases; Benzo(a)pyrene; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Line, Tumor; Dose-Response Relationship, Drug; Environmental Pollutants; Enzyme Activation; Enzyme Inhibitors; Glutamate-Cysteine Ligase; Glutathione; Glutathione Reductase; Glutathione Transferase; Humans; Inactivation, Metabolic; Liver Neoplasms; Oxidation-Reduction; Oxidative Stress; Up-Regulation; Xenobiotics | 2007 |
The mode of cisplatin-induced cell death in CYP2E1-overexpressing HepG2 cells: modulation by ERK, ROS, glutathione, and thioredoxin.
Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Caspases; Cell Death; Cisplatin; Cytochrome P-450 CYP2E1; Extracellular Signal-Regulated MAP Kinases; Glutathione; Humans; Liver Neoplasms; Necrosis; Reactive Oxygen Species; Thioredoxins; Tumor Cells, Cultured | 2007 |
Intracellular glutathione levels regulate Fos/Jun induction and activation of glutathione S-transferase gene expression.
Topics: Buthionine Sulfoximine; Carcinoma, Hepatocellular; Chloramphenicol O-Acetyltransferase; Diamide; Electron Spin Resonance Spectroscopy; Enzyme Induction; Gene Expression Regulation, Enzymologic; Genes, fos; Genes, jun; Glutathione; Glutathione Transferase; Humans; Methionine Sulfoximine; Proto-Oncogene Proteins c-fos; Proto-Oncogene Proteins c-jun; Tumor Cells, Cultured | 1994 |
Intracellular glutathione level modulates the induction of apoptosis by delta 12-prostaglandin J2.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Arsenites; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Division; Cycloheximide; DNA Fragmentation; Electrophoresis, Agar Gel; Enzyme Inhibitors; Glutathione; Humans; Liver Neoplasms; Prostaglandin D2; Sodium Compounds; Structure-Activity Relationship; Sulfhydryl Compounds; Tumor Cells, Cultured | 1996 |
CYP2E1 overexpression in HepG2 cells induces glutathione synthesis by transcriptional activation of gamma-glutamylcysteine synthetase.
Topics: Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cytochrome P-450 CYP2E1; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glutamate-Cysteine Ligase; Glutathione; Glutathione Peroxidase; Humans; Kinetics; Liver Neoplasms; Recombinant Proteins; Transcriptional Activation; Transfection; Tumor Cells, Cultured | 2000 |
Dual role of glutathione in selenite-induced oxidative stress and apoptosis in human hepatoma cells.
Topics: Acetylcysteine; Apoptosis; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Glutathione; Growth Inhibitors; Humans; Intracellular Fluid; L-Lactate Dehydrogenase; Liver Neoplasms; Oxidative Stress; Reactive Oxygen Species; Sodium Selenite; Tumor Cells, Cultured | 2000 |
Mechanism and significance of increased glutathione level in human hepatocellular carcinoma and liver regeneration.
Topics: Antioxidants; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Division; Cystine; DNA; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Hepatectomy; Humans; Liver; Liver Regeneration; NF-kappa B; Promoter Regions, Genetic; Protein Binding; Protein Subunits; Response Elements; RNA, Messenger; Transcription Factor AP-1; Tumor Cells, Cultured | 2001 |
Establishment of a human hepatoma cell line, HLE/2E1, suitable for detection of p450 2E1-related cytotoxicity.
Topics: Acetaminophen; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Division; Cell Line, Transformed; Cell Survival; Cytochrome P-450 CYP2E1; Ethanol; Gene Expression; Humans; Liver Neoplasms; Tumor Cells, Cultured | 2000 |
Modulation of cisplatin cytotoxicity and cisplatin-induced DNA cross-links in HepG2 cells by regulation of glutathione-related mechanisms.
Topics: Biological Transport; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Carrier Proteins; Cisplatin; Cross-Linking Reagents; DNA; DNA Damage; Dose-Response Relationship, Drug; Ethacrynic Acid; Glutathione; Glutathione Transferase; Humans; Hydrolyzable Tannins; Indomethacin; Membrane Transport Proteins; Oxidation-Reduction; Quercetin; Tumor Cells, Cultured | 2001 |
Down-regulation of intrinsic P-glycoprotein expression in multicellular prostate tumor spheroids by reactive oxygen species.
Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Cycle Proteins; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor p27; Cyclins; Drug Resistance, Multiple; Enzyme Inhibitors; Epidermal Growth Factor; Gene Expression Regulation, Neoplastic; Glutathione; Humans; Hydrogen Peroxide; JNK Mitogen-Activated Protein Kinases; Kinetics; Liver Neoplasms; Male; MAP Kinase Signaling System; Melanoma; Microtubule-Associated Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Prostatic Neoplasms; Protein-Tyrosine Kinases; Reactive Oxygen Species; Tumor Cells, Cultured; Tumor Suppressor Proteins | 2001 |
Toxicity by pyruvate in HepG2 cells depleted of glutathione: role of mitochondria.
Topics: Antioxidants; Apoptosis; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Catalase; Glutathione; Humans; Lipid Peroxidation; Mitochondria; Necrosis; Oxygen; Pyruvates; Sulfhydryl Compounds; Tumor Cells, Cultured | 2002 |
Arsenic trioxide-induced apoptosis and its enhancement by buthionine sulfoximine in hepatocellular carcinoma cell lines.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Caspases; Cell Division; Cell Nucleus; DNA Fragmentation; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Humans; Kinetics; Liver Neoplasms; Oxides; Reactive Oxygen Species; Tumor Cells, Cultured | 2002 |
Long-term buthionine-sulfoximine-mediated toxicity in cultured hepatoma cell lines.
Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Carcinoma, Hepatocellular; Cell Survival; Female; Glutathione; Humans; Liver Neoplasms; Liver Neoplasms, Experimental; Methionine Sulfoximine; Neoplasm Proteins; Time Factors; Tumor Cells, Cultured | 1990 |