buthionine sulfoximine has been researched along with Cancer of Ovary in 40 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (22.50) | 18.7374 |
| 1990's | 25 (62.50) | 18.2507 |
| 2000's | 2 (5.00) | 29.6817 |
| 2010's | 4 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Mos, M; Romero-Canelón, I; Sadler, PJ | 1 |
| Chan, SY; Ho, PC; Ong, PS | 1 |
| Kumar, A; Palakurthi, S; Vangara, KK; Yellepeddi, VK | 1 |
| Lohn, JW; Seifalian, AM; Toffa, SE; Winslet, MC; Yang, W | 1 |
| Green, JA; Hamilton, TC; Ozols, RF; Rogan, AM; Vistica, DT; Young, RC | 1 |
| Brooks, SE; Dupuis, NP; Holden, SA; Korbut, TT; Teicher, BA | 1 |
| Hiramatsu, H; Hirata, J; Ishii, K; Kikuchi, Y; Kita, T; Kudoh, K; Nagata, I | 1 |
| Harrap, KR; Kelland, LR; Loh, SY; Mistry, P | 1 |
| Mizutani, Y; Yoshida, O | 1 |
| Hirata, J; Imaizumi, E; Ishii, K; Kikuchi, Y; Kita, T; Kudoh, K; Nagata, I; Tode, T | 1 |
| Parekh, H; Simpkins, H | 1 |
| Andreotti, PE; Bruckner, HW; Krebs, D; Kurbacher, CM; Kurbacher, JA; Sass, G | 1 |
| al-Bassam, M; Buzaid, AC; Dasgupta, C; Fruehauf, JP; Kyshtoobayeva, A; Milovanovic, T; Parker, RJ; Zonis, S | 2 |
| Hobbs, S; Kelland, LR; Sharp, SY; Smith, V | 1 |
| Dimitriadis, KA; Geromichalos, GD; Kortsaris, AH; Kouretas, D; Papazisis, KT; Sivridis, E; Tsekreli, OK | 1 |
| Isonishi, S; Nozato, N; Ochiai, K; Ohtake, Y; Okamoto, A; Tagashira, M | 1 |
| Britt, P; Coley, HM; Elgie, AW; Hall, AG; Lewandowicz, GM; Sargent, JM; Williamson, CJ | 1 |
| Hong, YS; Kang, JH; Kim, DJ; Kim, HK; Lee, KS; Moon, HS; Park, JG | 1 |
| Lafleur, MV; Lankelma, J; Mans, DR; Pinedo, HM; Retèl, J; Schuurhuis, GJ; Treskes, M | 1 |
| Chen, CA; Collins, JL; Herzog, TJ; Mutch, DG | 1 |
| Durán, GE; Lau, DH; Lewis, AD; Sikic, BI | 1 |
| Bernhardt, G; Burgemeister, T; Gust, R; Keller, C; Mannschreck, A; Müller, R; Reile, H; Schönenberger, H; Spruss, T; vom Orde, HD | 1 |
| Hill, BT; Hosking, LK; Shellard, SA | 1 |
| Brown, R; McLaughlin, K; McMahon, N; Stephens, I | 1 |
| Lee, FY | 1 |
| Britten, RA; Broughton, C; Browning, PG; Green, JA; Warenius, HM; White, R | 1 |
| Frankfurt, OS; Seckinger, D; Sugarbaker, EV | 2 |
| Hamilton, TC; O'Dwyer, PJ; Ozols, RF; Young, RC | 1 |
| Chen, G; Zeller, WJ | 1 |
| Hamilton, TC; Lai, GM; Ozols, RF; Young, RC | 1 |
| Hamilton, TC; Ozols, RF; Young, RC | 2 |
| Andrews, PA; Howell, SB; Murphy, MP; Schiefer, MA | 1 |
| Behrens, BC; Dykes, D; Fine, RL; Hamilton, TC; Louie, KG; Ozols, RF; Plowman, J | 1 |
| Behrens, BC; Grotzinger, KR; Hamilton, TC; Kinsella, TJ; Louie, KG; McKoy, WM; Ozols, RF; Winker, MA | 1 |
| Batist, G; Behrens, BC; Grotzinger, KR; Hamilton, TC; Louie, KG; McKoy, WM; Ozols, RF; Tsuruo, T; Winker, MA; Young, RC | 1 |
| Andrews, PA; Howell, SB; Murphy, MP | 1 |
| Ator, MA; Bollt, O; Dorsey, BD; Kuwada, SK; Lao, X; Li, X; Lisko, JG; Ruggeri, BA; Scaife, CL; Shea, JE; Shen, Y; Theroff, JP; Zificsak, CA | 1 |
1 review(s) available for buthionine sulfoximine and Cancer of Ovary
| Article | Year |
|---|---|
The role of glutathione in drug resistance.
Topics: Antimetabolites; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; DNA Repair; Drug Resistance; Female; Glutathione; Humans; Melphalan; Methionine Sulfoximine; Ovarian Neoplasms | 1990 |
39 other study(ies) available for buthionine sulfoximine and Cancer of Ovary
| Article | Year |
|---|---|
Enhancement of Selectivity of an Organometallic Anticancer Agent by Redox Modulation.
Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Buthionine Sulfoximine; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cells, Cultured; Coordination Complexes; Female; Fibroblasts; Glutathione; Humans; Membrane Potential, Mitochondrial; Organometallic Compounds; Osmium; Ovarian Neoplasms; Oxidative Stress; Reactive Oxygen Species; Superoxides | 2015 |
Differential augmentative effects of buthionine sulfoximine and ascorbic acid in As2O3-induced ovarian cancer cell death: oxidative stress-independent and -dependent cytotoxic potentiation.
Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Ascorbic Acid; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Drug Synergism; Female; Fibroblasts; Glutathione; Glutathione Peroxidase; Humans; Intracellular Space; Ovarian Neoplasms; Oxidative Stress; Oxides | 2011 |
Comparative evaluation of small-molecule chemosensitizers in reversal of cisplatin resistance in ovarian cancer cells.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Cell Line, Tumor; CHO Cells; Cisplatin; Colchicine; Cricetinae; Cricetulus; Drug Resistance, Neoplasm; Drug Synergism; Female; Humans; Isoflavones; Mass Spectrometry; Ovarian Neoplasms; Sirolimus; Trientine | 2012 |
Malignant ascites increases the antioxidant ability of human ovarian (SKOV-3) and gastric adenocarcinoma (KATO-III) cells.
Topics: Adenocarcinoma; Antioxidants; Ascites; Blotting, Northern; Buthionine Sulfoximine; Cell Adhesion; Cell Line, Tumor; Cell Survival; Female; Gene Expression; Glutathione; Humans; Hyaluronan Receptors; Lipid Peroxidation; Malondialdehyde; Ovarian Neoplasms; Oxidative Stress; Stomach Neoplasms | 2005 |
Potentiation of melphalan cytotoxicity in human ovarian cancer cell lines by glutathione depletion.
Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Cystine; Drug Resistance; Drug Synergism; Female; Glutathione; Humans; Kinetics; Melphalan; Methionine Sulfoximine; Ovarian Neoplasms | 1984 |
Cytotoxicity of antitumor platinum complexes with L-buthionine-(R,S)-sulfoximine and/or etanidazole in human carcinoma cell lines sensitive and resistant to cisplatin.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Buthionine Sulfoximine; Carboplatin; Cisplatin; Drug Resistance; Etanidazole; Female; Humans; Methionine Sulfoximine; Organoplatinum Compounds; Ovarian Neoplasms; Tumor Cells, Cultured | 1995 |
[Potentiation of cisplatin sensitivity of cisplatin-resistant human ovarian cancer cell lines by L-buthionine-S,R-sulfoximine].
Topics: Adenocarcinoma; Adult; Buthionine Sulfoximine; Cisplatin; Drug Resistance; Drug Synergism; Female; Glutathione; Humans; Methionine Sulfoximine; Middle Aged; Ovarian Neoplasms; Tumor Cells, Cultured | 1994 |
Effect of buthionine sulfoximine on PtII and PtIV drug accumulation and the formation of glutathione conjugates in human ovarian-carcinoma cell lines.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Buthionine Sulfoximine; Carboplatin; Chromatography, High Pressure Liquid; Cisplatin; Culture Media; Drug Resistance; Female; Glutathione; Humans; Kinetics; Methionine Sulfoximine; Organoplatinum Compounds; Ovarian Neoplasms; Tumor Cells, Cultured | 1993 |
Overcoming tumor necrosis factor-alpha resistance of human renal and ovarian carcinoma cells by combination treatment with buthionine sulfoximine and tumor necrosis factor-alpha. Role of tumor necrosis factor-alpha mRNA down-regulation in tumor cell sensi
Topics: Acetylcysteine; Antimetabolites, Antineoplastic; Blotting, Northern; Buthionine Sulfoximine; Carcinoma, Renal Cell; Down-Regulation; Drug Resistance; Drug Synergism; Female; Glutathione; Humans; Kidney Neoplasms; Methionine Sulfoximine; Ovarian Neoplasms; RNA, Messenger; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1994 |
Modulation of sensitivity of human ovarian cancer cells to cis-diamminedichloroplatinum(II) by 12-O-tetradecanoylphorbol-13-acetate and D,L-buthionine-S,R-sulphoximine.
Topics: Buthionine Sulfoximine; Cell Division; Cisplatin; Cystadenocarcinoma; Drug Resistance; Female; Humans; Methionine Sulfoximine; Ovarian Neoplasms; Protein Kinase C; Tetradecanoylphorbol Acetate; Tumor Cells, Cultured | 1993 |
Cross-resistance and collateral sensitivity to natural product drugs in cisplatin-sensitive and -resistant rat lymphoma and human ovarian carcinoma cells.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Buthionine Sulfoximine; Cell Survival; Cisplatin; Colchicine; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Glutathione; Humans; Lymphoma; Methionine Sulfoximine; Mitosis; Ovarian Neoplasms; Paclitaxel; Rats; Tumor Cells, Cultured; Verapamil; Vinca Alkaloids | 1996 |
In vitro activity of titanocenedichloride versus cisplatin in four ovarian carcinoma cell lines evaluated by a microtiter plate ATP bioluminescence assay.
Topics: Adenocarcinoma; Adenosine Triphosphate; Buthionine Sulfoximine; Cell Count; Cell Death; Cisplatin; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Therapy, Combination; Female; Humans; Lethal Dose 50; Luminescent Measurements; Methionine Sulfoximine; Organometallic Compounds; Ovarian Neoplasms; Tumor Cells, Cultured | 1995 |
Selective and synergistic activity of L-S,R-buthionine sulfoximine on malignant melanoma is accompanied by decreased expression of glutathione-S-transferase.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Breast Neoplasms; Buthionine Sulfoximine; Carmustine; Drug Synergism; Female; Glutathione; Glutathione Transferase; Humans; Melanins; Melanoma; Ovarian Neoplasms; Tumor Cells, Cultured | 1997 |
Melanin content and downregulation of glutathione S-transferase contribute to the action of L-buthionine-S-sulfoximine on human melanoma.
Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Buthionine Sulfoximine; Carmustine; Down-Regulation; Drug Resistance; Enzyme Inhibitors; Female; Glutamate-Cysteine Ligase; Glutathione Transferase; Humans; Melanins; Melanoma; Melphalan; Ovarian Neoplasms; Tumor Cells, Cultured | 1998 |
Lack of a role for MRP1 in platinum drug resistance in human ovarian cancer cell lines.
Topics: Antineoplastic Agents; ATP-Binding Cassette Transporters; Blotting, Western; Buthionine Sulfoximine; Cisplatin; Drug Resistance, Neoplasm; Female; Humans; Multidrug Resistance-Associated Proteins; Organoplatinum Compounds; Ovarian Neoplasms; Tumor Cells, Cultured; Vincristine | 1998 |
Effects of melatonin on proliferation of cancer cell lines.
Topics: Breast Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Survival; Colonic Neoplasms; DNA Replication; DNA, Neoplasm; Dose-Response Relationship, Drug; Ethacrynic Acid; Female; Glutathione; Humans; Melatonin; Ovarian Neoplasms; Tumor Cells, Cultured; Uterine Cervical Neoplasms | 1998 |
5-Hydroxy-4-oxo-L-norvaline depletes intracellular glutathione: a new modulator of drug resistance.
Topics: Aminolevulinic Acid; Buthionine Sulfoximine; Drug Resistance, Multiple; Female; Glutamate-Cysteine Ligase; Glutathione; Glutathione Synthase; Humans; Ovarian Neoplasms; Saccharomyces cerevisiae; Soil Microbiology; Streptomyces; Tumor Cells, Cultured | 1999 |
Cellular glutathione content, in vitro chemoresponse, and the effect of BSO modulation in samples derived from patients with advanced ovarian cancer.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Buthionine Sulfoximine; Cisplatin; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Drug Synergism; Female; Glutathione; Humans; Multidrug Resistance-Associated Proteins; Ovarian Neoplasms; Pilot Projects; Prognosis; Tumor Cells, Cultured | 2002 |
Effects of buthionine sulfoximine treatment on cellular glutathione levels and cytotoxicities of cisplatin, carboplatin and radiation in human stomach and ovarian cancer cell lines.
Topics: Antimetabolites, Antineoplastic; Antineoplastic Agents; Buthionine Sulfoximine; Carboplatin; Cisplatin; Female; Glutathione; Humans; Methionine Sulfoximine; Ovarian Neoplasms; Radiation Tolerance; Radiation-Sensitizing Agents; Radiotherapy; Stomach Neoplasms; Tumor Cells, Cultured | 1992 |
Modulation by D,L-buthionine-S,R-sulphoximine of etoposide cytotoxicity on human non-small cell lung, ovarian and breast carcinoma cell lines.
Topics: Antimetabolites, Antineoplastic; Breast Neoplasms; Buthionine Sulfoximine; Carcinoma, Non-Small-Cell Lung; Cisplatin; Doxorubicin; Drug Synergism; Etoposide; Female; Glutathione; Humans; Lung Neoplasms; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil | 1992 |
The effects of cyclosporin A on the lysis of ovarian cancer cells by cisplatin or adriamycin.
Topics: Antimetabolites, Antineoplastic; Buthionine Sulfoximine; Cell Death; Cisplatin; Cycloheximide; Cyclosporine; Doxorubicin; Drug Interactions; Drug Resistance; Emetine; Female; Humans; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured; Verapamil | 1992 |
Sensitization of drug resistant human ovarian cancer cells to cyanomorpholino doxorubicin (MRA-CN) by modulation of glutathione metabolism.
Topics: Antibiotics, Antineoplastic; Buthionine Sulfoximine; Cell Survival; Doxorubicin; Drug Resistance; Ethacrynic Acid; Female; Glutathione; Humans; In Vitro Techniques; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured | 1992 |
[1,2-Bis(2-hydroxyphenyl)ethylenediamine]dichloroplatinum(II), a new compound for the therapy of ovarian cancer. III. Detailed evaluation of the antitumor activity of the enantiomeric complexes on the human NIH:OVCAR-3 ovarian cancer cell line.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Cisplatin; Female; Glutathione; Humans; Methionine Sulfoximine; Organoplatinum Compounds; Ovarian Neoplasms; Stereoisomerism; Structure-Activity Relationship; Tumor Cells, Cultured | 1992 |
Anomalous relationship between cisplatin sensitivity and the formation and removal of platinum-DNA adducts in two human ovarian carcinoma cell lines in vitro.
Topics: Buthionine Sulfoximine; Cisplatin; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Drug; Drug Resistance; Female; Glutathione; Glutathione Transferase; Humans; Methionine Sulfoximine; Ovarian Neoplasms; Platinum; Tumor Cells, Cultured | 1991 |
Single step selection of cis-diamminedichloroplatinum(II) resistant mutants from a human ovarian carcinoma cell line.
Topics: Aphidicolin; Buthionine Sulfoximine; Cell Survival; Cisplatin; Diterpenes; Drug Resistance; Female; Humans; Methionine Sulfoximine; Mutation; Ovarian Neoplasms; Phenotype; Tumor Cells, Cultured; Tumor Stem Cell Assay | 1991 |
Glutathione diminishes the anti-tumour activity of 4-hydroperoxycyclophosphamide by stabilising its spontaneous breakdown to alkylating metabolites.
Topics: Alkylating Agents; Animals; Antimetabolites; Buthionine Sulfoximine; Cyclophosphamide; Drug Synergism; Female; Glutathione; Humans; Intracellular Fluid; Kinetics; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Ovarian Neoplasms; Tumor Cells, Cultured | 1991 |
The relationship between nuclear glutathione levels and resistance to melphalan in human ovarian tumour cells.
Topics: Buthionine Sulfoximine; Cell Nucleus; Drug Resistance; Female; Glutathione; Humans; Melphalan; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured | 1991 |
Intercellular transfer of drug resistance.
Topics: Antimetabolites; Buthionine Sulfoximine; Cell Communication; Cell Survival; Cells, Cultured; Colony-Forming Units Assay; DNA; DNA Damage; Drug Resistance; Female; Flow Cytometry; Glutathione; Humans; In Vitro Techniques; Melphalan; Methionine Sulfoximine; Ovarian Neoplasms; Tetradecanoylphorbol Acetate | 1991 |
In vitro investigations on induction and reversal of cisplatin resistance in a rat ovarian tumor cell line.
Topics: Animals; Antimetabolites; Benzamides; Buthionine Sulfoximine; Cell Line; Cisplatin; DNA; Drug Resistance; Female; Glutathione; Glutathione Disulfide; In Vitro Techniques; Methionine Sulfoximine; Ovarian Neoplasms; Poly(ADP-ribose) Polymerase Inhibitors; Rats | 1990 |
Flow cytometric analysis of DNA damage and repair in the cells resistant to alkylating agents.
Topics: Alkylating Agents; Antibodies, Monoclonal; Buthionine Sulfoximine; Cell Line; Cell Survival; DNA Damage; DNA Repair; Dose-Response Relationship, Drug; Drug Resistance; Female; Flow Cytometry; Humans; Kinetics; Melphalan; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured | 1990 |
Effect of glutathione on DNA repair in cisplatin-resistant human ovarian cancer cell lines.
Topics: Aphidicolin; Buthionine Sulfoximine; Centrifugation, Density Gradient; Cisplatin; Diterpenes; DNA Polymerase II; DNA Repair; Drug Resistance; Female; Glutathione; Humans; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured | 1989 |
Cellular glutathione levels and sensitivity to radiation and antineoplastic agents in human ovarian cancer.
Topics: Buthionine Sulfoximine; Cell Survival; Cisplatin; Female; Glutathione; Humans; Melphalan; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured | 1988 |
Enhanced potentiation of cisplatin cytotoxicity in human ovarian carcinoma cells by prolonged glutathione depletion.
Topics: Buthionine Sulfoximine; Cisplatin; Cystadenocarcinoma; Drug Synergism; Female; Glutathione; Humans; Methionine Sulfoximine; Ovarian Neoplasms; Tumor Cells, Cultured | 1988 |
Enhanced melphalan cytotoxicity in human ovarian cancer in vitro and in tumor-bearing nude mice by buthionine sulfoximine depletion of glutathione.
Topics: Animals; Buthionine Sulfoximine; Colony-Forming Units Assay; Drug Resistance; Drug Synergism; Female; Glutathione; Histocytochemistry; Humans; Melphalan; Methionine Sulfoximine; Mice; Mice, Nude; Ovarian Neoplasms | 1987 |
Modulation of drug resistance in human ovarian cancer: experimental results and clinical applications.
Topics: Animals; Buthionine Sulfoximine; Cell Line; Doxorubicin; Drug Resistance; Drug Synergism; Female; Glutathione; Humans; Methionine Sulfoximine; Mice; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Transplantation, Heterologous; Verapamil | 1986 |
Radiation survival parameters of antineoplastic drug-sensitive and -resistant human ovarian cancer cell lines and their modification by buthionine sulfoximine.
Topics: Antineoplastic Agents; Buthionine Sulfoximine; Cell Line; Cell Survival; Drug Resistance; Female; Glutathione; Humans; Methionine Sulfoximine; Ovarian Neoplasms | 1985 |
Augmentation of adriamycin, melphalan, and cisplatin cytotoxicity in drug-resistant and -sensitive human ovarian carcinoma cell lines by buthionine sulfoximine mediated glutathione depletion.
Topics: Buthionine Sulfoximine; Cell Line; Cell Survival; Cisplatin; Doxorubicin; Drug Resistance; Drug Synergism; Female; Glutathione; Humans; Melphalan; Methionine Sulfoximine; Ovarian Neoplasms | 1985 |
Differential potentiation of alkylating and platinating agent cytotoxicity in human ovarian carcinoma cells by glutathione depletion.
Topics: Alkylating Agents; Buthionine Sulfoximine; Carcinoma; Cell Line; Drug Resistance; Drug Synergism; Female; Glutathione; Humans; Methionine Sulfoximine; Organoplatinum Compounds; Ovarian Neoplasms | 1985 |
Design, synthesis, and biological evaluation of sulfonyl acrylonitriles as novel inhibitors of cancer metastasis and spread.
Topics: Acrylonitrile; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Female; HT29 Cells; Humans; Mice; Molecular Structure; Ovarian Neoplasms; Pancreatic Neoplasms; Structure-Activity Relationship; Sulfones | 2015 |