buthionine sulfoximine has been researched along with Benign Neoplasms, Brain in 28 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.14) | 18.7374 |
| 1990's | 8 (28.57) | 18.2507 |
| 2000's | 8 (28.57) | 29.6817 |
| 2010's | 9 (32.14) | 24.3611 |
| 2020's | 1 (3.57) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashima, K; Katoh, H; Kimura, I | 1 |
| Du, S; Du, Y; Ren, J; Yan, Z; Ying, G; Zhu, Z | 1 |
| Blattmann, H; Bräuer-Krisch, E; Hildebrandt, G; Laissue, JA; Requardt, H; Schültke, E | 1 |
| Kayama, T; Kitanaka, C; Narita, Y; Okada, M; Sato, A; Seino, S; Shibui, S; Shibuya, K; Watanabe, E | 1 |
| Gülden, M; Klauser, E; Maser, E; Seibert, H; Seibert, S | 1 |
| Akutsu, H; Ishikawa, E; Matsuda, M; Matsumura, A; Nakai, K; Shirakawa, M; Yamamoto, T; Yoshida, F; Zaboronok, A | 1 |
| Belizário, JE; de Andrade-Lima, LC; Garcia, CC; Menck, CF; Munford, V; Quinet, A; Rocha, CR; Vieira, DB | 1 |
| Fortunato, RS; Kajitani, GS; Menck, CF; Quinet, A; Rocha, CR | 1 |
| Eaton, GR; Eaton, SS; Epel, B; Halpern, HJ; Kao, JPY; Krzykawska-Serda, M; Maggio, MC; Rosen, GM; Sundramoorthy, SV; Tseytlin, M | 1 |
| De Ciucis, C; Domenicotti, C; Marengo, B; Marinari, UM; Nitti, M; Passalacqua, M; Pronzato, MA; Ricciarelli, R; Zingg, JM | 1 |
| Hashimoto, K; Iyo, M; Komatsu, N; Shimizu, E | 1 |
| Kumada, H; Matsumura, A; Nakai, K; Yamamoto, T; Yoshida, F | 1 |
| Daniels, CK; Dukhande, VV; Hugus, JJ; Lai, JC; Malthankar-Phatak, GH | 1 |
| Hori, K; Ishii, K; Katayama, M; Sato, N; Waga, S; Yodoi, J | 1 |
| Baumgart, J; Dichgans, J; Klockgether, T; Reber, U; Seyfried, J; Trepel, M; Weller, M; Wüllner, U | 1 |
| Belcuig, M; Chopp, M; Grenier, J; Jiang, F; Li, Y; Lilge, L; Singh, G | 1 |
| Baraban, J; Brem, H; Burger, PC; Li, KW; Piantadosi, S; Ratan, R; Sipos, EP; Witham, TF | 1 |
| Anderson, CP; Bleyer, WA; Cairncross, JG; Cloughesy, T; Doolittle, ND; Eck, SL; Guastadisegni, P; Hall, WA; Muldoon, LL; Neuwelt, EA; Patel, SJ; Peereboom, D; Siegal, T | 1 |
| Deloughery, TG; Hasler, BP; Muldoon, LL; Neuwelt, EA; Pagel, MA | 1 |
| Ha, MS; Kim, YK; Lee, YW | 1 |
| Baumgart, J; Seyfried, J; Stock, J; Weller, M; Wick, W; Wüllner, U | 1 |
| Bigner, DD; Brizel, DM; Friedman, HS; Griffith, OW; Halperin, EC; Honore, G; Sontag, MR | 1 |
| Allalunis-Turner, MJ; Allen, PB; Aronyk, KE; Day, RS; Fulton, DS; Huyser-Wierenga, D; McKean, JD; Petruk, KC; Urtasun, RC; Weir, BK | 1 |
| Benchekroun, MN; Catroux, P; Montaudon, D; Robert, J | 1 |
| Bigner, DD; Fekete, I; Friedman, HS; Griffith, OW; Groothuis, DR; Schlageter, KE | 1 |
| Bigner, DD; Colvin, OM; Friedman, HS; Griffith, OW; Halperin, EC; Honore, G; Lippitz, BE; Ostertag, CB | 1 |
| Bodell, WJ; Doane-Setzer, P; Evans, CG; Smith, MT; Tokuda, K | 1 |
| Bigner, DD; Colvin, OM; Elion, GB; Friedman, HS; Griffith, OW; Hilton, J; Lippitz, B; Schold, SC | 1 |
28 other study(ies) available for buthionine sulfoximine and Benign Neoplasms, Brain
| Article | Year |
|---|---|
Role of ferritinophagy in cystine deprivation-induced cell death in glioblastoma cells.
Topics: Antimetabolites, Antineoplastic; Autophagy; Brain Neoplasms; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Cystine; Ferritins; Ferroptosis; Glioblastoma; Glutathione; Humans; Iron; Lipid Peroxidation; Oxidoreductases | 2021 |
Glutathione reductase mediates drug resistance in glioblastoma cells by regulating redox homeostasis.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Cisplatin; Dacarbazine; Disease-Free Survival; Drug Resistance, Neoplasm; Female; Gene Knockdown Techniques; Glioblastoma; Glutathione; Glutathione Reductase; Homeostasis; Humans; Mice; Mice, Inbred BALB C; Neoplasm Proteins; Oxidants; Oxidation-Reduction; Oxidative Stress; Reactive Oxygen Species; RNA, Small Interfering; Temozolomide; Tumor Stem Cell Assay; Xenograft Model Antitumor Assays | 2018 |
Survival of rats bearing advanced intracerebral F 98 tumors after glutathione depletion and microbeam radiation therapy: conclusions from a pilot project.
Topics: Animals; Antimetabolites; Brain Neoplasms; Buthionine Sulfoximine; Combined Modality Therapy; Dose-Response Relationship, Radiation; Glioma; Glutathione; Male; Pilot Projects; Radiotherapy; Rats; Rats, Inbred F344; Survival Rate; Synchrotrons | 2018 |
Pivotal role for ROS activation of p38 MAPK in the control of differentiation and tumor-initiating capacity of glioma-initiating cells.
Topics: Acetylcysteine; Animals; Brain Neoplasms; Buthionine Sulfoximine; Cell Differentiation; Down-Regulation; Forkhead Box Protein O3; Forkhead Transcription Factors; Glioma; Humans; Hydrogen Peroxide; Imidazoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Mitogen-Activated Protein Kinase 7; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Pyridines; Reactive Oxygen Species; RNA Interference; Transplantation, Heterologous | 2014 |
Additivity, antagonism, and synergy in arsenic trioxide-induced growth inhibition of C6 glioma cells: effects of genistein, quercetin and buthionine-sulfoximine.
Topics: Animals; Arsenic Trioxide; Arsenicals; Brain Neoplasms; Buthionine Sulfoximine; Cell Division; Cell Line, Tumor; Genistein; Glioma; Oxides; Quercetin; Rats | 2014 |
Pretreatment with buthionine sulfoximine enhanced uptake and retention of BSH in brain tumor.
Topics: Animals; Borohydrides; Boron Neutron Capture Therapy; Brain Neoplasms; Buthionine Sulfoximine; Drug Synergism; Male; Metabolic Clearance Rate; Organ Specificity; Premedication; Rats; Rats, Inbred F344; Sulfhydryl Compounds; Tissue Distribution | 2014 |
Glutathione depletion sensitizes cisplatin- and temozolomide-resistant glioma cells in vitro and in vivo.
Topics: Animals; Apoptosis; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Cell Survival; Cisplatin; Dacarbazine; Disease Progression; DNA Damage; DNA Repair; Drug Resistance, Neoplasm; Female; Glioma; Glutathione; Humans; Mice, Nude; Temozolomide; Tumor Suppressor Protein p53 | 2014 |
NRF2 and glutathione are key resistance mediators to temozolomide in glioma and melanoma cells.
Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Buthionine Sulfoximine; Cell Line, Tumor; Dacarbazine; Drug Resistance, Neoplasm; Female; Glioma; Glutathione; Humans; Melanoma; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Nude; NF-E2-Related Factor 2; Temozolomide; Xenograft Model Antitumor Assays | 2016 |
Imaging thiol redox status in murine tumors in vivo with rapid-scan electron paramagnetic resonance.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Diagnostic Imaging; Disulfides; Electron Spin Resonance Spectroscopy; Female; Fibrosarcoma; Glutathione; Imaging, Three-Dimensional; Kinetics; Mice; Mice, Inbred C3H; Neoplasms, Experimental; Nitrogen Oxides; Oxidation-Reduction; Signal-To-Noise Ratio; Spin Labels | 2017 |
PKCδ sensitizes neuroblastoma cells to L-buthionine-sulfoximine and etoposide inducing reactive oxygen species overproduction and DNA damage.
Topics: Antineoplastic Agents; Apoptosis; Brain Neoplasms; Buthionine Sulfoximine; DNA Damage; Enzyme Activation; Enzyme Inhibitors; Etoposide; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Neuroblastoma; Onium Compounds; Protein Kinase C-delta; Reactive Oxygen Species; RNA, Small Interfering; Transfection; Tumor Cells, Cultured | 2011 |
Roles of endogenous glutathione levels on 6-hydroxydopamine-induced apoptotic neuronal cell death in human neuroblastoma SK-N-SH cells.
Topics: Acetylcysteine; Apoptosis; Benzimidazoles; Brain Neoplasms; Buthionine Sulfoximine; Cystine; DNA Fragmentation; Fluorescent Dyes; Free Radical Scavengers; Glutathione; Humans; Neuroblastoma; Neurons; Oxidopamine; Sympatholytics; Tumor Cells, Cultured | 2002 |
Enhancement of sodium borocaptate (BSH) uptake by tumor cells induced by glutathione depletion and its radiobiological effect.
Topics: Animals; Borohydrides; Boron Neutron Capture Therapy; Brain Neoplasms; Buthionine Sulfoximine; Carcinoma, Squamous Cell; Cells, Cultured; Cricetinae; Down-Regulation; Gamma Rays; Glioma; Glutathione; Lung; Mice; Radiation-Sensitizing Agents; Rats; Relative Biological Effectiveness; Sulfhydryl Compounds | 2004 |
Manganese-induced neurotoxicity is differentially enhanced by glutathione depletion in astrocytoma and neuroblastoma cells.
Topics: Antimetabolites; Astrocytoma; Brain Neoplasms; Buthionine Sulfoximine; Cell Death; Cell Line, Tumor; Cell Survival; Dose-Response Relationship, Drug; Glutathione; Humans; Manganese Poisoning; Nerve Degeneration; Neuroblastoma | 2006 |
Neuroprotection by glial cells through adult T cell leukemia-derived factor/human thioredoxin (ADF/TRX).
Topics: Acetylcysteine; Animals; Antimetabolites, Antineoplastic; Astrocytoma; Blotting, Western; Brain Neoplasms; Buthionine Sulfoximine; Cell Survival; Cerebral Cortex; Cytokines; Glutathione; Growth Substances; Humans; Hydrogen Peroxide; Mercaptoethanol; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Neoplasm Proteins; Neuroglia; Thioredoxins; Tumor Cells, Cultured | 1994 |
Potentiation of treosulfan toxicity by the glutathione-depleting agent buthionine sulfoximine in human malignant glioma cells: the role of bcl-2.
Topics: Antineoplastic Agents, Alkylating; Brain Neoplasms; Busulfan; Buthionine Sulfoximine; Drug Synergism; Gene Transfer Techniques; Glioma; Glutathione; Humans; Prohibitins; Proto-Oncogene Proteins c-bcl-2; Tumor Cells, Cultured | 1998 |
Photodynamic therapy using Photofrin in combination with buthionine sulfoximine (BSO) to treat 9L gliosarcoma in rat brain.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain; Brain Chemistry; Brain Neoplasms; Buthionine Sulfoximine; Chromatography, High Pressure Liquid; Dihematoporphyrin Ether; Free Radicals; Gliosarcoma; Glutathione; Male; Necrosis; Oxidation-Reduction; Photochemotherapy; Radiation-Sensitizing Agents; Rats; Rats, Inbred F344; Reactive Oxygen Species | 1998 |
L-buthionine sulfoximine potentiates the antitumor effect of 4-hydroperoxycyclophosphamide when administered locally in a rat glioma model.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents; Brain; Brain Neoplasms; Buthionine Sulfoximine; Cyclophosphamide; Drug Combinations; Drug Implants; Drug Synergism; Glioma; Glutathione; Injections, Intraperitoneal; Liver; Male; Rats; Rats, Inbred F344; Reference Values; Survival Analysis | 2001 |
Importance of dose intensity in neuro-oncology clinical trials: summary report of the Sixth Annual Meeting of the Blood-Brain Barrier Disruption Consortium.
Topics: Adult; Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Blood-Brain Barrier; Bone Marrow Diseases; Bone Marrow Transplantation; Brain Neoplasms; Buthionine Sulfoximine; Child; Clinical Trials as Topic; Clinical Trials, Phase III as Topic; Cognition Disorders; Combined Modality Therapy; Cranial Irradiation; Dose-Response Relationship, Drug; Drug Synergism; Genetic Therapy; Genetic Vectors; Glioma; Glutathione; Guinea Pigs; Hearing Loss, Sensorineural; Hematopoietic Stem Cell Transplantation; Humans; Hypertonic Solutions; Lymphoma, Non-Hodgkin; Meningeal Neoplasms; Multicenter Studies as Topic; Neuroblastoma; Oligodendroglioma; Permeability; Quality of Life; Randomized Controlled Trials as Topic; Treatment Outcome | 2001 |
Therapeutic efficacy of aortic administration of N-acetylcysteine as a chemoprotectant against bone marrow toxicity after intracarotid administration of alkylators, with or without glutathione depletion in a rat model.
Topics: Acetylcysteine; Animals; Antimetabolites; Antineoplastic Agents, Alkylating; Aorta, Thoracic; Blood-Brain Barrier; Bone Marrow Diseases; Brain; Brain Neoplasms; Buthionine Sulfoximine; Carcinoma, Small Cell; Dose-Response Relationship, Drug; Drug Interactions; Female; Glutathione; Infusions, Intra-Arterial; Lung Neoplasms; Rats; Rats, Long-Evans; Tissue Distribution; Xenograft Model Antitumor Assays | 2001 |
Role of reactive oxygen species and glutathione in inorganic mercury-induced injury in human glioma cells.
Topics: Brain Neoplasms; Buthionine Sulfoximine; Cell Survival; Fluorescent Dyes; Free Radical Scavengers; Glioma; Glutathione; Humans; Kinetics; Mercuric Chloride; Nitroarginine; Reactive Oxygen Species; Spectrometry, Fluorescence; Tumor Cells, Cultured; Uric Acid | 2001 |
CD95/CD95 ligand-independent potentiation of treosulfan cytotoxicity by BSO in malignant glioma cells in vitro and in vivo.
Topics: Animals; Antimetabolites, Antineoplastic; Antineoplastic Agents, Alkylating; Apoptosis; Blood Cell Count; Brain Neoplasms; Busulfan; Buthionine Sulfoximine; Cell Division; Drug Synergism; Fas Ligand Protein; fas Receptor; Gene Transfer Techniques; Glioma; Glutathione; Humans; In Vitro Techniques; Ligands; Membrane Glycoproteins; Neoplasm Transplantation; Rats; Rats, Sprague-Dawley; Survival Rate; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 2002 |
The radiation dose-response relationship in a human glioma xenograft and an evaluation of the influence of glutathione depletion by buthionine sulfoximine.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Dose-Response Relationship, Radiation; Glioma; Glutathione; Humans; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Radiation-Sensitizing Agents; Survival Rate; Transplantation, Heterologous | 1992 |
Glutathione levels and chemosensitizing effects of buthionine sulfoximine in human malignant glioma cells.
Topics: Adolescent; Adult; Aged; Antimetabolites, Antineoplastic; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Child; Drug Screening Assays, Antitumor; Drug Synergism; Female; Glioma; Glutathione; Humans; Male; Mechlorethamine; Methionine Sulfoximine; Middle Aged; Tumor Cells, Cultured | 1991 |
Development of mechanisms of protection against oxidative stress in doxorubicin-resistant rat tumoral cells in culture.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Doxorubicin; Drug Resistance; Free Radicals; Glioblastoma; Glutathione; Lipid Peroxidation; Liver Neoplasms, Experimental; Membrane Glycoproteins; Methionine Sulfoximine; Oxidation-Reduction; Rats; Tumor Cells, Cultured; Vitamin E | 1990 |
Rate of buthionine sulfoximine entry into brain and xenotransplanted human gliomas.
Topics: Animals; Brain; Brain Neoplasms; Buthionine Sulfoximine; Capillaries; Diffusion; Glioma; Humans; Methionine Sulfoximine; Mice; Mice, Nude; Transplantation, Heterologous | 1990 |
L-buthionine-sulfoximine-mediated radiosensitization in experimental interstitial radiotherapy of intracerebral D-54 MG glioma xenografts in athymic mice.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Glioma; Male; Methionine Sulfoximine; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Radiation-Sensitizing Agents | 1990 |
Glutathione and related enzymes in rat brain tumor cell resistance to 1,3-bis(2-chloroethyl)-1-nitrosourea and nitrogen mustard.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Carmustine; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Clone Cells; Dinitrochlorobenzene; Drug Resistance; gamma-Glutamyltransferase; Glioma; Glutathione; Glutathione Transferase; Lomustine; Mechlorethamine; Methionine Sulfoximine; Rats; Semustine | 1987 |
Increased melphalan activity in intracranial human medulloblastoma and glioma xenografts following buthionine sulfoximine-mediated glutathione depletion.
Topics: Animals; Brain Neoplasms; Buthionine Sulfoximine; Drug Interactions; Female; Glioma; Glutathione; Humans; Male; Medulloblastoma; Melphalan; Methionine Sulfoximine; Mice; Mice, Nude; Neoplasm Transplantation | 1989 |