buthionine sulfoximine has been researched along with Acute Liver Injury, Drug-Induced in 44 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (15.91) | 18.7374 |
| 1990's | 11 (25.00) | 18.2507 |
| 2000's | 6 (13.64) | 29.6817 |
| 2010's | 15 (34.09) | 24.3611 |
| 2020's | 5 (11.36) | 2.80 |
| Authors | Studies |
|---|---|
| Gong, B; Hu, Z; Li, W; Liao, Y; Liu, T; Liu, Y; Luo, P; Pan, J; Tan, R; Zeng, Q; Zhang, S; Zheng, J | 1 |
| Abhyankar, S; Adelusi, O; Apte, U; Dawn, B; Duan, L; Jaeschke, H; Nguyen, NT; Ramachandran, A; Robarts, DR; Soder, RP; Umbaugh, DS; Woolbright, B | 1 |
| Hussain, Y; Luqman, S; Meena, A; Rajak, S; Raza, W; Singh, J; Sinha, RA | 1 |
| He, Y; Li, W; Liao, Y; Liu, T; Liu, Y; Peng, Y; Ran, G; Tan, R; Wang, X; Wu, C; Wu, Z; Zhang, S; Zheng, J | 1 |
| Miyazaki, N; Oda, S; Tsuneyama, K; Yokoi, T | 1 |
| Fan, YX; Jiang, LL; Jiang, Y; Li, HJ; Li, P; Yu, Q; Zhao, DS | 1 |
| Gonsebatt, ME; Valdovinos-Flores, C | 1 |
| Mally, A; Ramm, S | 1 |
| Fukami, T; Iida, A; Matsuo, K; Nakajima, M; Sasaki, E; Tsuneyama, K; Yokoi, T | 1 |
| Hatao, K; Kimura, T; Kodama, T; Kumada, K; Kumano, A; Mori, K; Takano, N; Takiguchi, S | 1 |
| Guan, L; Kim, SC; Kim, YW; Lee, JR; Park, SM; Wu, Y; Zhao, R; Zhao, Z | 1 |
| Gao, H; Li, W; Lin, D; Meng, D; Peng, Y; Smith, CV; Xu, Y; Zheng, J | 1 |
| Fukami, T; Iida, A; Nakajima, M; Sasaki, E; Tsuneyama, K; Yano, A; Yokoi, T | 1 |
| Gao, H; Guo, X; Lin, D; Peng, Y; Wang, K; Zheng, J | 1 |
| Aoki, T; Atsumi, R; Itokawa, K; Iwasaki, M; Izumi, T; Okazaki, O; Ono, C; Shimizu, S; Sudo, K | 1 |
| Gaarde, WA; Han, D; Jain, S; Kaplowitz, N; Shinohara, M; Than, TA; Win, S; Ybanez, MD | 1 |
| Gao, W; Minowa, Y; Mizukawa, Y; Nakatsu, N; Ohno, Y; Urushidani, T; Yamada, H | 1 |
| Fisher, RL; Sinclair, JR; Vickers, AE | 1 |
| Atsumi, R; Izumi, T; Nakazawa, T; Okazaki, O; Saji, H; Shimizu, S; Sudo, K | 1 |
| Fukami, T; Higuchi, S; Ide, M; Kobayashi, M; Nakajima, M; Nishikawa, S; Yokoi, T | 1 |
| Kakuni, M; Katoh, Y; Matsuo, K; Morita, M; Nakajima, M; Tateno, C; Yokoi, T | 1 |
| Cohen, SD; Dominick, PK; Roberts, JC; Slitt, AM | 1 |
| Anand, SS; Latendresse, JR; Mehendale, HM; Mumtaz, MM; Palkar, PS; Philip, BK | 1 |
| Brouwer, KL; Lee, JK; Leslie, EM; Zamek-Gliszczynski, MJ | 1 |
| Jean, PA; Roth, RA | 1 |
| Fujihara, Y; Iguchi, S; Kaneo, Y; Ogawa, K; Tanaka, T | 1 |
| Irie, Y; Mizutani, T; Nakanishi, K | 1 |
| Gandolfi, AJ; Hall, PM; Lind, RC | 1 |
| Carlson, GP; DeNicola, DB; Gadberry, MG | 1 |
| Takeyama, N; Tanaka, T; Uedono, Y; Yamagami, K | 1 |
| Kawazoe, S; Mizutani, T; Murakami, M; Shirai, M; Yoshida, K | 1 |
| Chen, TS; Song, H | 1 |
| Chan, HM; Cherian, MG; Tabarrok, R; Tamura, Y | 1 |
| Chong, MG; He, DE; Kelly, JH; Koussayer, T; Shang, TA; Sussman, NL; Whisennand, HH | 1 |
| Boyd, MR; Ravindranath, V | 1 |
| Mizutani, T; Nakanishi, K; Nomura, H; Satoh, K | 1 |
| Boelsterli, UA; Bouis, P | 1 |
| Anderson, ME; Meister, A; Singhal, RK | 1 |
| Corcoran, GB; Wong, BK | 1 |
| Nakagawa, Y; Tayama, K | 1 |
| Yeung, JH | 1 |
| Bauer, JA; Corcoran, GB; Lau, TW | 1 |
| Nakagawa, Y | 1 |
| Fujita, S; Mizutani, T; Nakanishi, K; Nomura, H | 1 |
44 other study(ies) available for buthionine sulfoximine and Acute Liver Injury, Drug-Induced
| Article | Year |
|---|---|
DNA damage by reactive oxygen species resulting from metabolic activation of 8-epidiosbulbin E acetate in vitro and in vivo.
Topics: Activation, Metabolic; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Diterpenes; DNA; DNA Damage; Glutathione; Mice; Reactive Oxygen Species | 2022 |
Human Wharton's Jelly-derived mesenchymal stem cells prevent acetaminophen-induced liver injury in a mouse model unlike human dermal fibroblasts.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chemical and Drug Induced Liver Injury, Chronic; Disease Models, Animal; Fibroblasts; Hepatocytes; Humans; Liver; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Wharton Jelly | 2022 |
Purpurin ameliorates alcohol-induced hepatotoxicity by reducing ROS generation and promoting Nrf2 expression.
Topics: Alanine Transaminase; Animals; Anthraquinones; Antioxidants; Aspartate Aminotransferases; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Cytochrome P-450 CYP2E1; Ethanol; Glutathione; Ligands; Mice; NF-E2-Related Factor 2; Oxidative Stress; Reactive Oxygen Species | 2022 |
DNA damage and up-regulation of PARP-1 induced by columbin in vitro and in vivo.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Diterpenes; DNA Damage; Glutathione; Lactones; Mice; Poly(ADP-ribose) Polymerase Inhibitors; Reactive Oxygen Species; Up-Regulation | 2023 |
Exacerbation of gefitinib-induced liver injury by glutathione reduction in mice.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Disease Progression; Gefitinib; Glutathione; Liver; Mice, Inbred C57BL; Oxidative Stress; Protein Kinase Inhibitors | 2020 |
CYP3A Activation and Glutathione Depletion Aggravate Emodin-Induced Liver Injury.
Topics: Animals; Buthionine Sulfoximine; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dexamethasone; Emodin; Glutathione; Hepatocytes; Humans; Male; Mass Spectrometry; Rats; Rats, Sprague-Dawley | 2018 |
Nerve growth factor exhibits an antioxidant and an autocrine activity in mouse liver that is modulated by buthionine sulfoximine, arsenic, and acetaminophen.
Topics: Acetaminophen; Animals; Antioxidants; Arsenic; Autocrine Communication; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Gene Expression Regulation; Liver; Mice; Nerve Growth Factor; Neurons; Oxidation-Reduction; Oxidative Stress; PC12 Cells; Phosphorylation; Rats; Receptor, trkA | 2013 |
Role of drug-independent stress factors in liver injury associated with diclofenac intake.
Topics: Acute-Phase Proteins; Animals; Anti-Inflammatory Agents, Non-Steroidal; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Diclofenac; Lipocalin-2; Lipocalins; Lipopolysaccharides; Male; NF-kappa B; Poly I-C; Proto-Oncogene Proteins; Rats; Rats, Sprague-Dawley; Stress, Physiological | 2013 |
A novel mouse model for phenytoin-induced liver injury: involvement of immune-related factors and P450-mediated metabolism.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Cytoprotection; Disease Models, Animal; Enzyme Inhibitors; Female; Glutathione; Immunity, Innate; Inflammasomes; Inflammation Mediators; Liver; Mice; Mice, Inbred C57BL; Necrosis; Oxidative Stress; Phenytoin; T-Lymphocytes, Helper-Inducer | 2013 |
Evaluation of hepatic damage by reactive metabolites--with consideration of circadian variation of murine hepatic glutathione levels.
Topics: Acetaminophen; Administration, Oral; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Circadian Rhythm; Disease Models, Animal; Glutathione; Liver; Male; Mice, Inbred BALB C; Osmosis; Time Factors; Water | 2014 |
Isoliquiritigenin attenuates oxidative hepatic damage induced by carbon tetrachloride with or without buthionine sulfoximine.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Carbon Tetrachloride; Chalcones; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP2E1; Enzyme Inhibitors; Histocytochemistry; Male; Random Allocation; Rats; Rats, Sprague-Dawley; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2015 |
Metabolic activation of furan moiety makes Diosbulbin B hepatotoxic.
Topics: Activation, Metabolic; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Furans; Glutathione; Heterocyclic Compounds, 4 or More Rings; Ketoconazole; Liver; Male; Mice; Structure-Activity Relationship | 2016 |
Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats.
Topics: Alanine Transaminase; Animals; Anti-Bacterial Agents; Antifungal Agents; Buthionine Sulfoximine; Carbamazepine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 CYP3A; Enzyme Induction; Enzyme Inhibitors; Glutathione; Hydroxylation; Ketoconazole; Liver; Male; Microsomes, Liver; Rats; Rats, Inbred F344; Troleandomycin | 2015 |
Lysine- and cysteine-based protein adductions derived from toxic metabolites of 8-epidiosbulbin E acetate.
Topics: Activation, Metabolic; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Dioscorea; Diterpenes; In Vitro Techniques; Ketoconazole; Lysine; Male; Medicine, East Asian Traditional; Mice; Microsomes, Liver; Oxidation-Reduction; Proteins | 2016 |
Metabolism-dependent hepatotoxicity of amodiaquine in glutathione-depleted mice.
Topics: Alanine Transaminase; Amodiaquine; Animals; Antimalarials; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Interactions; Enzyme Inhibitors; Glutathione; Lethal Dose 50; Liver Diseases; Male; Mice; Mice, Inbred BALB C; Models, Biological | 2009 |
Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; bcl-2-Associated X Protein; Buthionine Sulfoximine; Cells, Cultured; Chemical and Drug Induced Liver Injury; Cytoplasm; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Glutamate-Cysteine Ligase; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Hepatocytes; JNK Mitogen-Activated Protein Kinases; Male; Mice; Mice, Inbred C57BL; Mitochondria, Liver; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction | 2010 |
Mechanism-based biomarker gene sets for glutathione depletion-related hepatotoxicity in rats.
Topics: Animals; Bromobenzenes; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Gene Expression; Gene Expression Profiling; Genetic Markers; Glutathione; Ketones; Liver; Liver Function Tests; Male; Oligonucleotide Array Sequence Analysis; Rats; Rats, Sprague-Dawley | 2010 |
Glutathione modulation and oxidative stress in human liver slices.
Topics: Acetaminophen; Adenosine Triphosphate; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Gene Expression; Glutathione; Humans; In Vitro Techniques; Liver; Methimazole; Mitochondria; Oxidation-Reduction; Oxidative Stress | 2010 |
Ticlopidine-induced hepatotoxicity in a GSH-depleted rat model.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Enzyme Inhibitors; Glutathione; Platelet Aggregation Inhibitors; Protein Binding; Rats; Ticlopidine; Triazoles | 2011 |
Th2 cytokine-mediated methimazole-induced acute liver injury in mice.
Topics: Animals; Antibodies, Monoclonal; Antibodies, Neutralizing; Antimetabolites; Antithyroid Agents; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cytokines; Dose-Response Relationship, Drug; Female; GATA3 Transcription Factor; Gene Expression Regulation; Glutathione; Interleukin-4; Liver; Methimazole; Mice; Mice, Inbred BALB C; RNA, Messenger; Th2 Cells | 2012 |
Chimeric mice with a humanized liver as an animal model of troglitazone-induced liver injury.
Topics: Animals; Antineoplastic Agents; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromans; Dose-Response Relationship, Drug; Glutathione; Humans; Liver; Mice; Thiazolidinediones; Transplantation Chimera; Troglitazone | 2012 |
Effect of ribose cysteine pretreatment on hepatic and renal acetaminophen metabolite formation and glutathione depletion.
Topics: Acetaminophen; Animals; Blood Urea Nitrogen; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; In Vitro Techniques; Kidney; Kidney Diseases; L-Iditol 2-Dehydrogenase; Liver; Liver Diseases; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Prodrugs; Protective Agents; Thiazoles; Thiazolidines | 2005 |
Subchronic chloroform priming protects mice from a subsequently administered lethal dose of chloroform.
Topics: Alanine Transaminase; Animals; Area Under Curve; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chloroform; Cytochrome P-450 CYP2E1; Dose-Response Relationship, Drug; Drug Tolerance; Glutathione; Glutathione Reductase; Hepatocytes; Intubation, Gastrointestinal; Kidney; Kidney Diseases; Liver Diseases; Mice; Survival Rate | 2006 |
Modulation of trabectedin (ET-743) hepatobiliary disposition by multidrug resistance-associated proteins (Mrps) may prevent hepatotoxicity.
Topics: Animals; Animals, Genetically Modified; Anti-Inflammatory Agents; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP-Binding Cassette Transporters; Bile; Blotting, Western; Buthionine Sulfoximine; Cell Separation; Cell Survival; Cells, Cultured; Chemical and Drug Induced Liver Injury; Dexamethasone; Dioxoles; Enzyme Inhibitors; Hepatocytes; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Rats; Rats, Wistar; Tetrahydroisoquinolines; Trabectedin | 2008 |
Naphthylisothiocyanate disposition in bile and its relationship to liver glutathione and toxicity.
Topics: 1-Naphthylisothiocyanate; Animals; Bile; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Glutathione; Isomerism; Liver; Male; Methionine Sulfoximine; Rats; Rats, Sprague-Dawley | 1995 |
A protective effect of glutathione-dextran macromolecular conjugates on acetaminophen-induced hepatotoxicity dependent on molecular size.
Topics: Acetaminophen; Animals; Antimetabolites; Aspartate Aminotransferases; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, Gel; Chromatography, High Pressure Liquid; Cyanogen Bromide; Delayed-Action Preparations; Dextrans; Disease Models, Animal; Drug Delivery Systems; Glutathione; In Vitro Techniques; Injections, Intravenous; Liver; Liver Diseases; Male; Methionine Sulfoximine; Mice; Molecular Weight; Survival Rate | 1994 |
Styrene-induced hepatotoxicity in mice depleted of glutathione.
Topics: Alanine Transaminase; Animals; Antimetabolites; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Dose-Response Relationship, Drug; Glutathione; Liver Diseases; Male; Methionine Sulfoximine; Mice; Oxygenases; Styrene; Styrenes; Sulfhydryl Compounds | 1994 |
A model for fatal halothane hepatitis in the guinea pig.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Glutathione; Guinea Pigs; Halothane; Liver; Male; Methionine Sulfoximine; Necrosis | 1994 |
Pneumotoxicity and hepatotoxicity of styrene and styrene oxide.
Topics: Animals; Benzoflavones; beta-Naphthoflavone; Bronchoalveolar Lavage Fluid; Buthionine Sulfoximine; Carcinogens; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme System; Epoxy Compounds; gamma-Glutamyltransferase; Injections, Intraperitoneal; L-Iditol 2-Dehydrogenase; L-Lactate Dehydrogenase; Liver; Liver Diseases; Lung Diseases; Male; Methionine Sulfoximine; Mice; Phenobarbital; Pyridines; Styrene; Styrenes; Trichloroepoxypropane | 1996 |
Lipopolysaccharide-mediated hepatic glutathione depletion and progressive mitochondrial damage in mice: protective effect of glutathione monoethyl ester.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cytosol; Female; Glutathione; Kinetics; L-Lactate Dehydrogenase; Lipopolysaccharides; Liver; Liver Diseases; Membrane Potentials; Mice; Mice, Inbred ICR; Mitochondria, Liver; Organ Size; Reactive Oxygen Species; Sucrose | 1997 |
Evidence for the involvement of N-methylthiourea, a ring cleavage metabolite, in the hepatotoxicity of methimazole in glutathione-depleted mice: structure-toxicity and metabolic studies.
Topics: Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Disease Models, Animal; Gas Chromatography-Mass Spectrometry; Glutathione; Liver; Male; Methimazole; Mice; Mice, Inbred ICR; Necrosis; Structure-Activity Relationship; Thiourea | 2000 |
p-Aminophenol-induced liver toxicity: tentative evidence of a role for acetaminophen.
Topics: Acetaminophen; Acetylation; Alanine Transaminase; Aminophenols; Animals; Ascorbic Acid; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Chromatography, High Pressure Liquid; Cysteine; Cystine; Dose-Response Relationship, Drug; Drug Synergism; Glutathione; Glutathione Disulfide; L-Iditol 2-Dehydrogenase; Liver; Male; Mice; Mice, Inbred C57BL | 2001 |
The relative importance of glutathione and metallothionein on protection of hepatotoxicity of menadione in rats.
Topics: Acetylcysteine; Animals; Buthionine Sulfoximine; Calcium; Chemical and Drug Induced Liver Injury; Cytosol; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Metallothionein; Methionine Sulfoximine; Phenobarbital; Potassium; Rats; Rats, Sprague-Dawley; Sulfates; Vitamin K; Zinc; Zinc Sulfate | 1992 |
An improved model of acetaminophen-induced fulminant hepatic failure in dogs.
Topics: Acetaminophen; Alanine Transaminase; Animals; Biopsy; Blood Glucose; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Dogs; Liver; Liver Diseases; Male; Methemoglobinemia; Methionine Sulfoximine; Pulmonary Edema; Vacuoles | 1992 |
Effect of modulators of glutathione synthesis on the hepatotoxicity of 2-methylfuran.
Topics: Alanine Transaminase; Animals; Antimetabolites; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cystine; Drug Interactions; Furans; Glutathione; Male; Maleates; Methionine Sulfoximine; Pyrrolidonecarboxylic Acid; Rats; Rats, Inbred Strains; Thiazoles; Thiazolidines | 1991 |
Hepatotoxicity of eugenol in mice depleted of glutathione by treatment with DL-buthionine sulfoximine.
Topics: Alanine Transaminase; Animals; Antimetabolites; Benzoflavones; beta-Naphthoflavone; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Eugenol; Glutathione; Liver; Liver Circulation; Male; Methionine Sulfoximine; Mice; Mice, Inbred Strains; Organ Size; Phenobarbital | 1991 |
Modulation of cocaine metabolism in primary rat hepatocyte cultures: effects on irreversible binding and protein biosynthesis.
Topics: Analysis of Variance; Animals; Antimetabolites; Aroclors; Buthionine Sulfoximine; Cells, Cultured; Chemical and Drug Induced Liver Injury; Chlorodiphenyl (54% Chlorine); Cocaine; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Glutathione; In Vitro Techniques; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Proteins; Pyridines; Rats; Rats, Inbred Strains | 1990 |
Glutathione, a first line of defense against cadmium toxicity.
Topics: 1-Propanol; Animals; Buthionine Sulfoximine; Cadmium; Cadmium Chloride; Chemical and Drug Induced Liver Injury; Glutamate-Cysteine Ligase; Glutathione; Male; Metallothionein; Methionine Sulfoximine; Mice | 1987 |
Effects of esterase inhibitors and buthionine sulfoximine on the prevention of acetaminophen hepatotoxicity by N-acetylcysteine.
Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Esterases; Isoflurophate; Lysine; Male; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Nitrophenols; Organophosphorus Compounds; Phenylmethylsulfonyl Fluoride | 1987 |
Effect of buthionine sulfoximine on orthophenylphenol-induced hepato- and nephrotoxic potential in male rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Biphenyl Compounds; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Glutathione; Kidney; Kidney Diseases; Liver; Male; Methionine Sulfoximine; Organ Size; Rats; Rats, Inbred F344; Time Factors | 1988 |
Effect of sulphydryl drugs on paracetamol-induced hepatotoxicity in mice.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Animals; Antimetabolites; Blood Proteins; Buthionine Sulfoximine; Chemical and Drug Induced Liver Injury; Cysteine; Glutathione; Liver; Male; Methionine Sulfoximine; Mice; Mice, Inbred ICR; Sulfhydryl Compounds | 1988 |
Immediate rise in intracellular calcium and glycogen phosphorylase a activities upon acetaminophen covalent binding leading to hepatotoxicity in mice.
Topics: Acetaminophen; Administration, Oral; Animals; Buthionine Sulfoximine; Calcium; Chemical and Drug Induced Liver Injury; Enzyme Activation; Glutathione; Liver Diseases; Male; Methionine Sulfoximine; Mice; Phosphorylase a; Phosphorylases; Protein Binding | 1988 |
Effects of buthionine sulfoximine and cysteine on the hepatotoxicity of butylated hydroxytoluene in rats.
Topics: Alanine Transaminase; Animals; Aspartate Aminotransferases; Buthionine Sulfoximine; Butylated Hydroxytoluene; Chemical and Drug Induced Liver Injury; Cysteine; Drug Interactions; Glutathione; Lethal Dose 50; Liver Diseases; Male; Methionine Sulfoximine; Rats; Rats, Inbred F344 | 1987 |
Hepatotoxicity of butylated hydroxytoluene and its analogs in mice depleted of hepatic glutathione.
Topics: Alanine Transaminase; Animals; Buthionine Sulfoximine; Butylated Hydroxytoluene; Calcium; Chemical and Drug Induced Liver Injury; Disulfides; Glutathione; Liver; Male; Methionine Sulfoximine; Mice | 1987 |