butenafine has been researched along with Recrudescence in 2 studies
butenafine: studied on experimental dermatophytosis
butenafine : Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated the safety and efficacy of twice-daily butenafine versus its vehicle in the treatment of interdigital tinea pedis in a multicenter, randomized, double-blind, parallel-group trial." | 9.08 | One-week therapy with twice-daily butenafine 1% cream versus vehicle in the treatment of tinea pedis: a multicenter, double-blind trial. ( De Villez, RL; Elewski, B; Hong, S; Jones, T; Lowe, N; Lucky, A; Reyes, B; Savin, R; Stewart, D; Willis, I, 1997) |
| "The effectiveness of topical terbinafine (TBF) to tinea pedis was evaluated an animal model in which guinea pigs were experimentally infected through their planta pedis with Trichophyton mentagrophytes, then a 1% TBF or butenafine (BTF) cream was administered topically once daily for 4 consecutive weeks." | 7.69 | [A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis]. ( Kudoh, M; Uchida, K; Yamaguchi, H, 1994) |
| "We evaluated the safety and efficacy of twice-daily butenafine versus its vehicle in the treatment of interdigital tinea pedis in a multicenter, randomized, double-blind, parallel-group trial." | 5.08 | One-week therapy with twice-daily butenafine 1% cream versus vehicle in the treatment of tinea pedis: a multicenter, double-blind trial. ( De Villez, RL; Elewski, B; Hong, S; Jones, T; Lowe, N; Lucky, A; Reyes, B; Savin, R; Stewart, D; Willis, I, 1997) |
| "The effectiveness of topical terbinafine (TBF) to tinea pedis was evaluated an animal model in which guinea pigs were experimentally infected through their planta pedis with Trichophyton mentagrophytes, then a 1% TBF or butenafine (BTF) cream was administered topically once daily for 4 consecutive weeks." | 3.69 | [A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis]. ( Kudoh, M; Uchida, K; Yamaguchi, H, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uchida, K | 1 |
| Kudoh, M | 1 |
| Yamaguchi, H | 1 |
| Savin, R | 1 |
| De Villez, RL | 1 |
| Elewski, B | 1 |
| Hong, S | 1 |
| Jones, T | 1 |
| Lowe, N | 1 |
| Lucky, A | 1 |
| Reyes, B | 1 |
| Stewart, D | 1 |
| Willis, I | 1 |
1 trial available for butenafine and Recrudescence
| Article | Year |
|---|---|
One-week therapy with twice-daily butenafine 1% cream versus vehicle in the treatment of tinea pedis: a multicenter, double-blind trial.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antifunga | 1997 |
1 other study available for butenafine and Recrudescence
| Article | Year |
|---|---|
[A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis].
Topics: Administration, Topical; Animals; Antifungal Agents; Benzylamines; Disease Models, Animal; Drug Eval | 1994 |