butenafine has been researched along with Disease Models, Animal in 3 studies
butenafine: studied on experimental dermatophytosis
butenafine : Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effectiveness of topical terbinafine (TBF) to tinea pedis was evaluated an animal model in which guinea pigs were experimentally infected through their planta pedis with Trichophyton mentagrophytes, then a 1% TBF or butenafine (BTF) cream was administered topically once daily for 4 consecutive weeks." | 7.69 | [A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis]. ( Kudoh, M; Uchida, K; Yamaguchi, H, 1994) |
| "Butenafine is a novel antifungal agent of the class of benzylamines." | 5.28 | Topical treatment with butenafine significantly lowers relapse rate in an interdigital tinea pedis model in guinea pigs. ( Arika, T; Yamaguchi, H; Yokoo, M, 1992) |
| "The effectiveness of topical terbinafine (TBF) to tinea pedis was evaluated an animal model in which guinea pigs were experimentally infected through their planta pedis with Trichophyton mentagrophytes, then a 1% TBF or butenafine (BTF) cream was administered topically once daily for 4 consecutive weeks." | 3.69 | [A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis]. ( Kudoh, M; Uchida, K; Yamaguchi, H, 1994) |
| "Butenafine is a novel antifungal agent of the class of benzylamines." | 1.28 | Topical treatment with butenafine significantly lowers relapse rate in an interdigital tinea pedis model in guinea pigs. ( Arika, T; Yamaguchi, H; Yokoo, M, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Uchida, K | 1 |
| Kudoh, M | 1 |
| Yamaguchi, H | 2 |
| Arika, T | 1 |
| Yokoo, M | 1 |
3 other studies available for butenafine and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
[A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis].
Topics: Administration, Topical; Animals; Antifungal Agents; Benzylamines; Disease Models, Animal; Drug Eval | 1994 |
Topical treatment with butenafine significantly lowers relapse rate in an interdigital tinea pedis model in guinea pigs.
Topics: Administration, Topical; Animals; Antifungal Agents; Benzylamines; Disease Models, Animal; Guinea Pi | 1992 |