butenafine has been researched along with Dermatomycoses in 4 studies
butenafine: studied on experimental dermatophytosis
butenafine : Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.
Dermatomycoses: Superficial infections of the skin or its appendages by any of various fungi.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Butenafine was investigated for its activity against guinea pig dermatophytosis caused by Trichophyton mentagrophytes or Microsporum canis in comparison with those of naftifine, tolnaftate, clotrimazole, and bifonazole." | 1.28 | Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs. ( Amemiya, K; Arika, T; Hase, T; Maeda, T; Yamaguchi, H; Yokoo, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singal, A | 1 |
| Abdul Bari, MA | 1 |
| Odom, RB | 1 |
| Arika, T | 1 |
| Yokoo, M | 1 |
| Hase, T | 1 |
| Maeda, T | 1 |
| Amemiya, K | 1 |
| Yamaguchi, H | 1 |
1 review available for butenafine and Dermatomycoses
| Article | Year |
|---|---|
Butenafine and superficial mycoses: current status.
Topics: Animals; Antifungal Agents; Benzylamines; Clinical Trials as Topic; Dermatomycoses; Humans; Naphthal | 2008 |
1 trial available for butenafine and Dermatomycoses
| Article | Year |
|---|---|
Comparison of superficial mycosis treatment using Butenafine and Bifonazole nitrate clinical efficacy.
Topics: Administration, Topical; Adolescent; Adult; Aged; Analysis of Variance; Antifungal Agents; Benzylami | 2012 |
2 other studies available for butenafine and Dermatomycoses
| Article | Year |
|---|---|
Update on topical therapy for superficial fungal infections: focus on butenafine.
Topics: Antifungal Agents; Benzylamines; Dermatomycoses; History, 20th Century; Naphthalenes | 1997 |
Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental dermatophytosis in guinea pigs.
Topics: Animals; Antifungal Agents; Benzylamines; Dermatomycoses; Gas Chromatography-Mass Spectrometry; Guin | 1990 |