butenafine has been researched along with Athlete's Foot in 9 studies
butenafine: studied on experimental dermatophytosis
butenafine : Trimethylamine in which hydrogen atoms attached to different methyl groups are substituted by 1-naphthyl and 4-tert-butylphenyl groups. It is an inhibitor of squalene epoxidase, an enzyme responsible for the creation of sterols needed in fungal cell membranes, and is used as its hydrochloride salt for treatment of dermatological fungal infections.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We evaluated butenafine in the treatment of tinea pedis in a controlled, randomized, double-blind trial." | 9.08 | Treatment of interdigital tinea pedis with a 4-week once-daily regimen of butenafine hydrochloride 1% cream. ( Elewski, B; Gorsulowsky, DC; Pariser, DM; Tschen, E, 1997) |
| "We evaluated the safety and efficacy of twice-daily butenafine versus its vehicle in the treatment of interdigital tinea pedis in a multicenter, randomized, double-blind, parallel-group trial." | 9.08 | One-week therapy with twice-daily butenafine 1% cream versus vehicle in the treatment of tinea pedis: a multicenter, double-blind trial. ( De Villez, RL; Elewski, B; Hong, S; Jones, T; Lowe, N; Lucky, A; Reyes, B; Savin, R; Stewart, D; Willis, I, 1997) |
| "Butenafine, a derivative of benzylamine with potent fungicidal activity is a new generation of antimycotic compound that has shown to be extremely effective against experimentally-induced tinea pedis in the guinea-pig, a situation that resembles synergetic pathology similar to that of tinea pedis in humans." | 8.80 | Butenafine hydrochloride: for the treatment of interdigital tinea pedis. ( Maibach, HI; Syed, TA, 2000) |
| "The effectiveness of topical terbinafine (TBF) to tinea pedis was evaluated an animal model in which guinea pigs were experimentally infected through their planta pedis with Trichophyton mentagrophytes, then a 1% TBF or butenafine (BTF) cream was administered topically once daily for 4 consecutive weeks." | 7.69 | [A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis]. ( Kudoh, M; Uchida, K; Yamaguchi, H, 1994) |
| "Butenafine is a novel antifungal agent of the class of benzylamines." | 5.28 | Topical treatment with butenafine significantly lowers relapse rate in an interdigital tinea pedis model in guinea pigs. ( Arika, T; Yamaguchi, H; Yokoo, M, 1992) |
| "Butenafine is a new antifungal benzylamine." | 5.28 | Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental tinea pedis in guinea pigs. ( Amemiya, K; Arika, T; Maeda, T; Yamaguchi, H; Yokoo, M, 1990) |
| "We evaluated butenafine in the treatment of tinea pedis in a controlled, randomized, double-blind trial." | 5.08 | Treatment of interdigital tinea pedis with a 4-week once-daily regimen of butenafine hydrochloride 1% cream. ( Elewski, B; Gorsulowsky, DC; Pariser, DM; Tschen, E, 1997) |
| "We evaluated the safety and efficacy of twice-daily butenafine versus its vehicle in the treatment of interdigital tinea pedis in a multicenter, randomized, double-blind, parallel-group trial." | 5.08 | One-week therapy with twice-daily butenafine 1% cream versus vehicle in the treatment of tinea pedis: a multicenter, double-blind trial. ( De Villez, RL; Elewski, B; Hong, S; Jones, T; Lowe, N; Lucky, A; Reyes, B; Savin, R; Stewart, D; Willis, I, 1997) |
| "Butenafine, a derivative of benzylamine with potent fungicidal activity is a new generation of antimycotic compound that has shown to be extremely effective against experimentally-induced tinea pedis in the guinea-pig, a situation that resembles synergetic pathology similar to that of tinea pedis in humans." | 4.80 | Butenafine hydrochloride: for the treatment of interdigital tinea pedis. ( Maibach, HI; Syed, TA, 2000) |
| "The effectiveness of topical terbinafine (TBF) to tinea pedis was evaluated an animal model in which guinea pigs were experimentally infected through their planta pedis with Trichophyton mentagrophytes, then a 1% TBF or butenafine (BTF) cream was administered topically once daily for 4 consecutive weeks." | 3.69 | [A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis]. ( Kudoh, M; Uchida, K; Yamaguchi, H, 1994) |
| "Butenafine is a novel antifungal agent of the class of benzylamines." | 1.28 | Topical treatment with butenafine significantly lowers relapse rate in an interdigital tinea pedis model in guinea pigs. ( Arika, T; Yamaguchi, H; Yokoo, M, 1992) |
| "Butenafine is a new antifungal benzylamine." | 1.28 | Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental tinea pedis in guinea pigs. ( Amemiya, K; Arika, T; Maeda, T; Yamaguchi, H; Yokoo, M, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (77.78) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Uchida, K | 1 |
| Kudoh, M | 1 |
| Yamaguchi, H | 3 |
| Tschen, E | 1 |
| Elewski, B | 2 |
| Gorsulowsky, DC | 1 |
| Pariser, DM | 1 |
| Savin, R | 1 |
| De Villez, RL | 1 |
| Hong, S | 1 |
| Jones, T | 1 |
| Lowe, N | 1 |
| Lucky, A | 1 |
| Reyes, B | 1 |
| Stewart, D | 1 |
| Willis, I | 1 |
| Reyes, BA | 1 |
| Beutner, KR | 1 |
| Cullen, SI | 1 |
| Rosen, T | 1 |
| Shupack, JL | 1 |
| Weinstein, MB | 1 |
| Syed, TA | 1 |
| Maibach, HI | 1 |
| Tanuma, H | 1 |
| Doi, M | 1 |
| Ohta, Y | 1 |
| Abe, M | 1 |
| Kume, H | 1 |
| Mukai, H | 1 |
| Katsuoka, K | 1 |
| Arika, T | 2 |
| Yokoo, M | 2 |
| Maeda, T | 1 |
| Amemiya, K | 1 |
1 review available for butenafine and Athlete's Foot
| Article | Year |
|---|---|
Butenafine hydrochloride: for the treatment of interdigital tinea pedis.
Topics: Animals; Antifungal Agents; Benzylamines; Humans; Naphthalenes; Tinea Pedis | 2000 |
3 trials available for butenafine and Athlete's Foot
| Article | Year |
|---|---|
Treatment of interdigital tinea pedis with a 4-week once-daily regimen of butenafine hydrochloride 1% cream.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antifungal Agents; Benzylamines; Double-Blind Meth | 1997 |
One-week therapy with twice-daily butenafine 1% cream versus vehicle in the treatment of tinea pedis: a multicenter, double-blind trial.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Analysis of Variance; Antifunga | 1997 |
Butenafine, a fungicidal benzylamine derivative, used once daily for the treatment of interdigital tinea pedis.
Topics: Adult; Antifungal Agents; Benzylamines; Double-Blind Method; Drug Administration Schedule; Female; H | 1998 |
5 other studies available for butenafine and Athlete's Foot
| Article | Year |
|---|---|
[A study on effectiveness of treatment and prevention of relapse using topical administration of terbinafine in a guinea pig model for tinea pedis].
Topics: Administration, Topical; Animals; Antifungal Agents; Benzylamines; Disease Models, Animal; Drug Eval | 1994 |
Topical butenafine for tinea pedis.
Topics: Administration, Topical; Antifungal Agents; Benzylamines; Humans; Naphthalenes; Randomized Controlle | 1997 |
Butenafine hydrochloride (Mentax) cream for the treatment of hyperkeratotic type tinea pedis and its transfer into the horny layer, with or without concomitant application of 20% urea ointment (Keratinamin).
Topics: Administration, Topical; Adult; Aged; Antifungal Agents; Benzylamines; Drug Therapy, Combination; Fe | 2001 |
Topical treatment with butenafine significantly lowers relapse rate in an interdigital tinea pedis model in guinea pigs.
Topics: Administration, Topical; Animals; Antifungal Agents; Benzylamines; Disease Models, Animal; Guinea Pi | 1992 |
Effects of butenafine hydrochloride, a new benzylamine derivative, on experimental tinea pedis in guinea pigs.
Topics: Animals; Antifungal Agents; Benzylamines; Guinea Pigs; Male; Naphthalenes; Tinea Pedis; Trichophyton | 1990 |