Page last updated: 2024-10-24

busulfan and Thrombocythemia, Essential

busulfan has been researched along with Thrombocythemia, Essential in 85 studies

Thrombocythemia, Essential: A clinical syndrome characterized by repeated spontaneous hemorrhages and a remarkable increase in the number of circulating platelets.

Research Excerpts

ExcerptRelevanceReference
"Therapeutic options for patients with polycythemia vera (PV) and essential thrombocythemia (ET) resistant or intolerant to hydroxyurea are limited."9.19Busulfan in patients with polycythemia vera or essential thrombocythemia refractory or intolerant to hydroxyurea. ( Alvarez-Larrán, A; Ancochea, A; Angona, A; Antelo, ML; Bellosillo, B; Besses, C; Burgaleta, C; Cervantes, F; Durán, MA; Ferrer-Marín, F; Gómez, M; Gómez-Casares, MT; Hernández-Boluda, JC; Marcote, B; Martínez-Avilés, L; Martínez-Trillos, A; Mata, MI; Senín, A; Vicente, V; Xicoy, B, 2014)
" From 1974 to 1986 we treated 20 symptomatic ET patients with microvascular circulation disturbances including erythromelalgia (N = 18), atypical or typical transient ischemic attacks (N = 6), or acute coronary ischemic syndrome (N = 3) with aspirin and one course of busulfan."9.09Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia. ( Michiels, JJ, 1999)
"Hydroxyurea (HU) has traditionally been the first-line treatment for patients with polycythemia vera (PV) or essential thrombocythemia (ET) at high risk for vascular complications."8.90Therapeutic options for patients with polycythemia vera and essential thrombocythemia refractory/resistant to hydroxyurea. ( Newberry, KJ; Sever, M; Verstovsek, S, 2014)
"In polycythemia vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%."7.69Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. ( Fisher, SG; Godwin, J; Nand, S; Stock, W, 1996)
"Therapeutic options for patients with polycythemia vera (PV) and essential thrombocythemia (ET) resistant or intolerant to hydroxyurea are limited."5.19Busulfan in patients with polycythemia vera or essential thrombocythemia refractory or intolerant to hydroxyurea. ( Alvarez-Larrán, A; Ancochea, A; Angona, A; Antelo, ML; Bellosillo, B; Besses, C; Burgaleta, C; Cervantes, F; Durán, MA; Ferrer-Marín, F; Gómez, M; Gómez-Casares, MT; Hernández-Boluda, JC; Marcote, B; Martínez-Avilés, L; Martínez-Trillos, A; Mata, MI; Senín, A; Vicente, V; Xicoy, B, 2014)
" From 1974 to 1986 we treated 20 symptomatic ET patients with microvascular circulation disturbances including erythromelalgia (N = 18), atypical or typical transient ischemic attacks (N = 6), or acute coronary ischemic syndrome (N = 3) with aspirin and one course of busulfan."5.09Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia. ( Michiels, JJ, 1999)
"We have previously demonstrated that hydroxyurea (HU) reduces the rate of vascular complications in patients with essential thrombocythaemia (ET) at high risk of thrombosis."5.09Second malignancies in patients with essential thrombocythaemia treated with busulphan and hydroxyurea: long-term follow-up of a randomized clinical trial. ( Barbui, T; Finazzi, G; Rodeghiero, F; Ruggeri, M, 2000)
"Hydroxyurea (HU) has traditionally been the first-line treatment for patients with polycythemia vera (PV) or essential thrombocythemia (ET) at high risk for vascular complications."4.90Therapeutic options for patients with polycythemia vera and essential thrombocythemia refractory/resistant to hydroxyurea. ( Newberry, KJ; Sever, M; Verstovsek, S, 2014)
"In polycythemia vera (PV), treatment with chlorambucil and radioactive phosphorus (p32) increases the risk of leukemic transformation from 1% to 13-14%."3.69Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis. ( Fisher, SG; Godwin, J; Nand, S; Stock, W, 1996)
" Two patients had been treated with uracil mustard: One developed acute myelogenous leukemia 79 months after institution of therapy, and the other patient developed chronic myelomonocytic leukemia 24 months after the start of therapy."3.67Essential thrombocythemia and leukemic transformation. ( Curtis, JL; Levin, J; Sedlacek, SM; Weintraub, J, 1986)
"Controlled studies are needed to confirm the clinical outcome value of twice-daily vs once-daily aspirin dosing and the therapeutic role of pegylated interferons and direct oral anticoagulants."2.66Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2020)
"Treatment with busulfan or interferon-α is usually effective in hydroxyurea failures."2.48Polycythemia vera and essential thrombocythemia: 2012 update on diagnosis, risk stratification, and management. ( Tefferi, A, 2012)
"Aspirin (ASS) was the most frequently used drug in 47 of 93 recorded cases (51%)."2.39Essential thrombocythemia and pregnancy. ( Griesshammer, M; Heimpel, H; Pearson, TC, 1996)
"The risk of major thrombosis is higher in ET patients aged more than 60 ys."2.39Treatment strategies in essential thrombocythemia. A critical appraisal of various experiences in different centers. ( Barbui, T; Brière, J; Dupuy, E; Finazzi, G; Kiladjian, JJ, 1996)
"Risk of thrombosis is higher in JAK2-mutated ET."1.51Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management. ( Barbui, T; Tefferi, A, 2019)
"This study indicates that in myelofibrosis, NMA regimens result in high engraftment failure rates."1.42Effect of conditioning regimens on graft failure in myelofibrosis: a retrospective analysis. ( Broers, AE; Janssen, JJ; Raymakers, R; Slot, S; Smits, K; Te Boekhorst, PA; van de Donk, NW; Witte, BI; Zweegman, S, 2015)
"Since bone marrow biopsy revealed myelofibrosis, she received anabolic hormone therapy."1.35[Long-term remission of non-Hodgkin lymphoma secondary to the treatment for essential thrombocythemia]. ( Kubota, Y; Waki, M, 2009)
"Hydroxyurea and myelosan were mostly used as cytostatic drugs while erythrocyte mass transfusions and hemoexfusions (phlebotomy)--for life-support."1.32[Choice of therapy and overall survival in patients with chronic myeloproliferative diseases]. ( Pop, VP; Rukavitsyn, OA; Seriakov, AP, 2004)
"The patient who had trisomy 8 at the time of diagnosis underwent myeloid blastic transformation in 35 months."1.31Leukemic transformation with trisomy 8 in essential thrombocythemia: a report of four cases. ( Hirose, Y; Masaki, Y; Sugai, S, 2002)
"Busulfan was given again for 40 days (a total of 80 mg) in another hospital when the platelet count increased to 71."1.30[Complete remission of essential thrombocythemia after recovery from severe bone marrow aplasia induced by busulfan treatment]. ( Hamaguchi, H; Nagata, K; Yamamoto, K, 1997)
"A 91-year-old patient with essential thrombocythemia presented with marked bone marrow suppression induced by long-term administration of busulfan."1.29[Effect of G-CSF and M-CSF on busulfan-induced marrow failure in a 91-year old patient with essential thrombocythemia]. ( Kubota, K; Kurabayashi, H; Shirakura, T; Take, H; Tamura, K, 1993)

Research

Studies (85)

TimeframeStudies, this research(%)All Research%
pre-199039 (45.88)18.7374
1990's22 (25.88)18.2507
2000's15 (17.65)29.6817
2010's7 (8.24)24.3611
2020's2 (2.35)2.80

Authors

AuthorsStudies
Tefferi, A7
Barbui, T6
Renso, R1
Aroldi, A1
Pioltelli, P1
Gambacorti-Passerini, C1
Elli, EM1
Sever, M1
Newberry, KJ1
Verstovsek, S1
Alvarez-Larrán, A1
Martínez-Avilés, L1
Hernández-Boluda, JC1
Ferrer-Marín, F1
Antelo, ML1
Burgaleta, C1
Mata, MI1
Xicoy, B1
Martínez-Trillos, A1
Gómez-Casares, MT1
Durán, MA1
Marcote, B1
Ancochea, A1
Senín, A1
Angona, A1
Gómez, M1
Vicente, V1
Cervantes, F1
Bellosillo, B1
Besses, C1
Slot, S1
Smits, K1
van de Donk, NW1
Witte, BI1
Raymakers, R1
Janssen, JJ1
Broers, AE1
Te Boekhorst, PA1
Zweegman, S1
Begna, K1
Abdelatif, A1
Schwager, S1
Hanson, C1
Pardanani, A1
Radaelli, F1
Onida, F1
Rossi, FG1
Zilioli, VR1
Colombi, M1
Usardi, P1
Calori, R1
Zanella, A1
Kubota, Y1
Waki, M1
Sironi, M1
Bertola, G1
Lodato, A1
Spinelli, M1
Sciariada, L1
Deeg, HJ1
Gooley, TA1
Flowers, ME1
Sale, GE1
Slattery, JT1
Anasetti, C1
Chauncey, TR1
Doney, K1
Georges, GE1
Kiem, HP1
Martin, PJ1
Petersdorf, EW1
Radich, J1
Sanders, JE1
Sandmaier, BM1
Warren, EH1
Witherspoon, RP1
Storb, R1
Appelbaum, FR1
EISEN, B1
BUTZ, WC1
WEBB, AT1
MEYER, FL1
LONSER, ER1
CAMPANALE, RP1
BARBIERI, U1
ASCARI, E1
GOBBI, F1
RYDER, RJ1
HALL, WJ1
OHLER, WG1
FRIEDERICI, L1
CASTENHOLZ, A1
Candoni, A1
Tiribelli, M1
Fanin, R1
Rukavitsyn, OA1
Pop, VP1
Seriakov, AP1
Mizukoshi, T1
Fujino, Y1
Yasukawa, K1
Matumoto, H1
Matsumura, S1
Nagasaki, T1
Ohno, K1
Tsujimoto, H1
Shimoda, T1
Shvidel, L1
Sigler, E1
Haran, M1
Klepfish, A1
Duek, A1
Berrebi, A2
Shtalrid, M1
Krug, K1
Rohrberg, R1
Wessel, H1
Zurborn, KH1
Bruhn, HD1
Feller, A1
Sanz Marca, A1
Rico Pérez, MT1
Aboín Massieu, FJ1
Rebollar Mesa, JL1
Grebe, G1
Alvo, M1
Lira, P1
Barria, C1
Mezzano, D1
Monsalve, V1
Linker, H1
Lindner, HJ1
Reuter, H1
Gross, R1
Take, H1
Tamura, K1
Kurabayashi, H1
Kubota, K1
Shirakura, T1
Bieniaszewska, M1
Hellmann, A1
Kabata, J1
Rasze-Ja-Specht, A1
van Genderen, PJ1
Michiels, JJ3
Arnar, DO1
Pétursson, MK1
Jónmundsson, E1
Björnsdóttir, J1
Tura, S1
Meisel, S1
Shpilberg, O1
Ramot, B1
Ben-Bassat, I1
Grande, M1
Nand, S1
Stock, W1
Godwin, J1
Fisher, SG1
Carulli, G1
Minnucci, S1
Gianfaldoni, ML1
Angiolini, C1
Azzarà, A1
Ambrogi, F1
Griesshammer, M1
Heimpel, H1
Pearson, TC2
Finazzi, G3
Dupuy, E1
Kiladjian, JJ1
Brière, J1
Fernández, MC1
Gardelegui, I1
Capote, FJ1
Gil, JL1
Muñoz, JA1
Yamamoto, K1
Nagata, K1
Hamaguchi, H1
Randi, ML6
Barbone, E1
Zerbinati, P1
Soini, B1
Rossi, C3
Girolami, A6
Brodsky, I1
Fabris, F5
Menapace, L1
Ruggeri, M1
Rodeghiero, F2
Jantunen, R1
Juvonen, E1
Ikkala, E1
Oksanen, K1
Anttila, P1
Ruutu, T1
Wright, CA1
Hirose, Y1
Masaki, Y1
Sugai, S1
Selroos, O1
van Assendelft, A1
Singh, AK2
Wetherley-Mein, G2
Droszcz, W1
Mdzewski, B1
Wrońska, J1
Porembińska, H1
Jedrzejewski, R1
Bogacka-Zatorska, H1
Leifer, W1
Leifer, G1
Lennert, K1
Nagai, K1
Schwarze, EW1
Jeri, A1
Horna, E1
Rojas, M1
Grossi, A1
Vannucchi, AM1
Longo, G1
Rafanelli, D1
Rossi Ferrini, P1
Scheffer, MG1
Simoons, ML1
Roelandt, JR1
Cortelazzo, S1
Viero, P1
D'Emilio, A1
Benassi, G1
Ricci, P1
Calbucci, F1
Cacciatore, FM1
D'Alessandro, R1
Knottenbelt, E1
Hallett, J1
Jacobs, P1
Sedlacek, SM1
Curtis, JL1
Weintraub, J1
Levin, J1
Pozzato, G1
Terpin, MM1
Rinaldi, C1
Frezza, M1
Krupsky, M1
Van de Pette, JE1
Prochazka, AV1
Dickson, ER1
Stathakis, NE1
Papayannis, AG1
Arapakis, G1
Gardikas, C1
Jamshidi, K1
Ansari, A1
Windschitl, HE1
Swaim, WR1
Solhaug, JH1
Martinez, J1
Shapiro, SS1
Holburn, RR1
Wiik, AS1
Paulson, OB1
Sorensen, CM1
Visfeldt, J1
Williams, DW1
Brandt, L1
Torre-Lopez, E1
Sanchez-Medal, L1
McNutt, DR1
Fudenberg, HH1
Silverstein, MN1
Ravich, RB1
Gunz, FW1
Thompson, IL1
Reed, CS1
Prankerd, TA1
Frinovskaia, IV1
Epstein, IS1

Reviews

12 reviews available for busulfan and Thrombocythemia, Essential

ArticleYear
Polycythemia vera: 2024 update on diagnosis, risk-stratification, and management.
    American journal of hematology, 2023, Volume: 98, Issue:9

    Topics: Busulfan; Female; Humans; Janus Kinase 2; Leukemia, Myeloid, Acute; Leukocytosis; Male; Microcircula

2023
Polycythemia vera and essential thrombocythemia: 2021 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2020, Volume: 95, Issue:12

    Topics: Age Factors; Aspirin; Busulfan; Calreticulin; Disease-Free Survival; Humans; Interferon-alpha; Janus

2020
Therapeutic options for patients with polycythemia vera and essential thrombocythemia refractory/resistant to hydroxyurea.
    Leukemia & lymphoma, 2014, Volume: 55, Issue:12

    Topics: Antineoplastic Agents; Busulfan; Disease Management; Drug Resistance; Histone Deacetylase Inhibitors

2014
Polycythemia vera and essential thrombocythemia: 2012 update on diagnosis, risk stratification, and management.
    American journal of hematology, 2012, Volume: 87, Issue:3

    Topics: Acute Disease; Age Factors; Alkylating Agents; Anticoagulants; Aspirin; Busulfan; Disease Management

2012
Plasma cell leukemia occurring in a patient with thrombocythemia treated with hydroxyurea and busulphan.
    Leukemia & lymphoma, 2004, Volume: 45, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Membe

2004
Primary thrombocythemia: diagnosis, clinical manifestations and management.
    Annals of hematology, 1993, Volume: 67, Issue:2

    Topics: Adolescent; Adult; Aged; Busulfan; Child; Diagnosis, Differential; Female; Hemorrhage; Humans; Hydro

1993
The management of elderly patients with myeloproliferative disorders.
    Hematological oncology, 1993, Volume: 11 Suppl 1

    Topics: Adult; Age Factors; Aged; Bone Marrow Transplantation; Busulfan; Chronic Disease; Humans; Hydroxyure

1993
Essential thrombocythemia and pregnancy.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Aspirin; Busulfan; Combined Modality Therapy; Di

1996
Treatment strategies in essential thrombocythemia. A critical appraisal of various experiences in different centers.
    Leukemia & lymphoma, 1996, Volume: 22 Suppl 1

    Topics: Adult; Aged; Alkylating Agents; Anemia, Megaloblastic; Arrhythmias, Cardiac; Bone Marrow Diseases; B

1996
A single institutional experience with 43 pregnancies in essential thrombocythemia.
    European journal of haematology, 2001, Volume: 66, Issue:3

    Topics: Abortion, Induced; Abortion, Spontaneous; Abruptio Placentae; Adult; Anticoagulants; Aspirin; Busulf

2001
Patho-anatomical features of the bone marrow.
    Clinics in haematology, 1975, Volume: 4, Issue:2

    Topics: Bone Marrow; Busulfan; Diagnosis, Differential; Erythropoiesis; Granulocytes; Humans; Leukemia, Myel

1975
[Essential thrombocythemia: conventional therapy].
    Haematologica, 1991, Volume: 76 Suppl 3

    Topics: Adult; Antineoplastic Agents; Busulfan; Follow-Up Studies; Hemorrhage; Humans; Hydroxyurea; Immunolo

1991

Trials

6 trials available for busulfan and Thrombocythemia, Essential

ArticleYear
Busulfan in patients with polycythemia vera or essential thrombocythemia refractory or intolerant to hydroxyurea.
    Annals of hematology, 2014, Volume: 93, Issue:12

    Topics: Aged; Aged, 80 and over; Alkylating Agents; Blood Cell Count; Busulfan; Comorbidity; Disease Progres

2014
Allogeneic hematopoietic stem cell transplantation for myelofibrosis.
    Blood, 2003, Dec-01, Volume: 102, Issue:12

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Cause of Death; C

2003
Busulphan is safe and efficient treatment in elderly patients with essential thrombocythemia.
    Leukemia, 2007, Volume: 21, Issue:9

    Topics: Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Busulfan; Female; Humans; Male; Middle A

2007
Normal life expectancy and thrombosis-free survival in aspirin treated essential thrombocythemia.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 1999, Volume: 5, Issue:1

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Busulfan; Coronary Disease; Dise

1999
Aspirin seems as effective as myelosuppressive agents in the prevention of rethrombosis in essential thrombocythemia.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 1999, Volume: 5, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Busulfan; Disease-Free Survival; Female; Hemorr

1999
Second malignancies in patients with essential thrombocythaemia treated with busulphan and hydroxyurea: long-term follow-up of a randomized clinical trial.
    British journal of haematology, 2000, Volume: 110, Issue:3

    Topics: Acute Disease; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Busul

2000

Other Studies

67 other studies available for busulfan and Thrombocythemia, Essential

ArticleYear
Long-term and low-dose of busulfan is a safe and effective second-line treatment in elderly patients with essential thrombocythemia resistant or intolerant to hydroxyurea.
    Blood cancer journal, 2018, 06-11, Volume: 8, Issue:6

    Topics: Age Factors; Aged; Antineoplastic Agents, Alkylating; Busulfan; Drug Resistance; Female; Humans; Hyd

2018
Polycythemia vera and essential thrombocythemia: 2019 update on diagnosis, risk-stratification and management.
    American journal of hematology, 2019, Volume: 94, Issue:1

    Topics: Adult; Aspirin; Bone Marrow; Busulfan; Disease Management; Disease Progression; Hemorrhage; Humans;

2019
Effect of conditioning regimens on graft failure in myelofibrosis: a retrospective analysis.
    Bone marrow transplantation, 2015, Volume: 50, Issue:11

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Busulfan; Calreticulin; Com

2015
Busulfan for the treatment of myeloproliferative neoplasms: the Mayo Clinic experience.
    Blood cancer journal, 2016, 05-27, Volume: 6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Alkylating; Busulfan; Female; Humans; Male; M

2016
Second malignancies in essential thrombocythemia (ET): a retrospective analysis of 331 patients with long-term follow-up from a single institution.
    Hematology (Amsterdam, Netherlands), 2008, Volume: 13, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Alkylating Agents; Busulfan; Drug Therapy, Combination;

2008
[Long-term remission of non-Hodgkin lymphoma secondary to the treatment for essential thrombocythemia].
    [Rinsho ketsueki] The Japanese journal of clinical hematology, 2009, Volume: 50, Issue:3

    Topics: Alkylating Agents; Antibodies, Monoclonal; Antibodies, Monoclonal, Murine-Derived; Antineoplastic Co

2009
Transition of essential thrombocythemia to megakaryoblastic leukemia after long-term therapy with sequential busulfan, pipobroman and hydroxyurea.
    Acta haematologica, 2003, Volume: 109, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Marrow; Busulfan; Humans; Hydroxyurea; Leukemia

2003
Primary hemorrhagic thrombocythemia treated with Myeleran.
    Journal of the Medical Association of Georgia, 1962, Volume: 51

    Topics: Blood Platelets; Busulfan; Hemorrhagic Disorders; Humans; Thrombocythemia, Essential

1962
Hemorrhagic thrombocythemia. Response to busulfan.
    Archives of internal medicine, 1963, Volume: 111

    Topics: Blood Platelets; Busulfan; Female; Hemorrhage; Humans; Postpartum Hemorrhage; Postpartum Period; Thr

1963
PRIMARY THROMBOCYTHEMIA: A SURGICAL PARADOX. REPORT OF A CASE.
    The Journal of the International College of Surgeons, 1964, Volume: 42

    Topics: Blood Platelets; Busulfan; Cell Count; Drug Therapy; Hemorrhagic Disorders; Humans; Hyperplasia; Meg

1964
[HEMORRHAGIC THROMBOCYTHEMIA AND THE "MYELOPROLIFERATIVE SYNDROME"].
    Nordisk medicin, 1964, Dec-03, Volume: 72

    Topics: Anemia; Anemia, Hypochromic; Blood Platelets; Busulfan; Gastrointestinal Hemorrhage; Hemorrhage; Hem

1964
[HEMORRHAGIC THROMBOCYTHEMIA].
    Minerva medica, 1964, Oct-17, Volume: 55

    Topics: Blood Platelet Disorders; Blood Platelets; Busulfan; Hemorrhagic Disorders; Humans; Phospholipids; R

1964
HAEMORRHAGIC THROMBOCYTHAEMIA.
    Journal of the Irish Medical Association, 1965, Volume: 56

    Topics: Blood Coagulation Tests; Blood Platelet Disorders; Blood Platelets; Busulfan; Drug Therapy; Humans;

1965
HEMORRHAGIC THROMBOCYTHEMIA: REPORT OF A CASE.
    JAMA, 1965, Jun-07, Volume: 192

    Topics: Bone Marrow Examination; Busulfan; Chromosomes; Diagnosis; Drug Therapy; Humans; Purpura; Thrombocyt

1965
[CONTRIBUTION TO THE CLINICAL PICTURE OF HEMORRHAGIC THROMBOCYTHEMIA].
    Die Medizinische Welt, 1965, May-08, Volume: 19

    Topics: Busulfan; Hemorrhagic Disorders; Leukocyte Disorders; Leukocytosis; Thrombocythemia, Essential

1965
[Choice of therapy and overall survival in patients with chronic myeloproliferative diseases].
    Voprosy onkologii, 2004, Volume: 50, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Busulfan;

2004
Essential thrombocythemia in a dog.
    The Journal of veterinary medical science, 2006, Volume: 68, Issue:11

    Topics: Animals; Busulfan; Dog Diseases; Dogs; Drug Therapy, Combination; Male; Prednisolone; Thrombocythemi

2006
[Megakaryocytic pseudomyelosis with severe thrombocytosis].
    Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete, 1981, Oct-01, Volume: 36, Issue:19

    Topics: Aged; Alkaline Phosphatase; Alpha-Globulins; Busulfan; Female; Humans; Leucyl Aminopeptidase; Liver;

1981
[Therapy of blast crises in megakaryocytic myelosis].
    Deutsche medizinische Wochenschrift (1946), 1984, Apr-06, Volume: 109, Issue:14

    Topics: Busulfan; Female; Humans; Middle Aged; Neoplastic Stem Cells; Stem Cells; Thrombocythemia, Essential

1984
[Essential thrombocythemia. Apropos of 3 cases].
    Revista clinica espanola, 1983, Mar-15, Volume: 168, Issue:5

    Topics: Adult; Aged; Anticoagulants; Busulfan; Female; Humans; Male; Thrombocythemia, Essential

1983
[Essential thrombocythemia: clinical and laboratory study of 6 cases].
    Revista medica de Chile, 1983, Volume: 111, Issue:12

    Topics: Aged; Bone Marrow; Busulfan; Female; Humans; Male; Middle Aged; Platelet Aggregation; Platelet Count

1983
[Long-term treatment of thrombocytosis and thrombocythemia].
    Die Medizinische Welt, 1980, Apr-04, Volume: 31, Issue:14

    Topics: Busulfan; Humans; Myeloproliferative Disorders; Pyrimethamine; Thrombocythemia, Essential; Thrombocy

1980
[Effect of G-CSF and M-CSF on busulfan-induced marrow failure in a 91-year old patient with essential thrombocythemia].
    Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics, 1993, Volume: 30, Issue:10

    Topics: Aged; Aged, 80 and over; Bone Marrow; Busulfan; Female; Granulocyte Colony-Stimulating Factor; Human

1993
[Essential thrombocythemia--clinical course from personal material].
    Polskie Archiwum Medycyny Wewnetrznej, 1994, Volume: 92, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Busulfan; Female; Humans; Hydroxyurea; Interferon-alpha; Male; Middl

1994
Renovascular hypertension and coronary heart disease complicating essential thrombocythemia.
    European heart journal, 1993, Volume: 14, Issue:4

    Topics: Adult; Angioplasty, Balloon; Busulfan; Coronary Disease; Humans; Hypertension, Renovascular; Male; R

1993
Essential thrombocythemia: a relative benign long-term course.
    Israel journal of medical sciences, 1993, Volume: 29, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Busulfan; Female; Follow-Up Studies; Hemoglobins; Humans

1993
Central nervous system granulocytic sarcoma in a patient with essential thrombocythemia.
    American journal of hematology, 1996, Volume: 51, Issue:1

    Topics: Acute Disease; Adult; Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Blast Crisi

1996
Leukemogenic risk of hydroxyurea therapy in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis.
    American journal of hematology, 1996, Volume: 52, Issue:1

    Topics: Acute Disease; Anemia, Refractory, with Excess of Blasts; Busulfan; Cell Transformation, Neoplastic;

1996
Interactions between platelets and neutrophils in essential thrombocythaemia. Effects on neutrophil chemiluminescence and superoxide anion generation.
    European journal of clinical investigation, 1995, Volume: 25, Issue:12

    Topics: Adult; Aged; Blood Platelets; Busulfan; Female; Humans; Luminescent Measurements; Male; Middle Aged;

1995
[Acute myeloid leukemia developing in the course of essential thrombocythemia].
    Sangre, 1996, Volume: 41, Issue:5

    Topics: Alkylating Agents; Busulfan; Cerebral Hemorrhage; Disease Progression; Fatal Outcome; Gingival Hemor

1996
[Complete remission of essential thrombocythemia after recovery from severe bone marrow aplasia induced by busulfan treatment].
    Gan to kagaku ryoho. Cancer & chemotherapy, 1997, Volume: 24, Issue:3

    Topics: Anemia, Aplastic; Busulfan; Erythropoietin; Female; Granulocyte Colony-Stimulating Factor; Humans; M

1997
Essential thrombocythemia following polycythemia vera: an unusual sequence.
    Journal of medicine, 1996, Volume: 27, Issue:5-6

    Topics: Aged; Aged, 80 and over; Alkylating Agents; Busulfan; Hematocrit; Humans; Leukocyte Count; Male; Pho

1996
Busulfan versus hydroxyurea in the treatment of polycythemia vera (PV) and essential thrombocythemia (ET)
    American journal of clinical oncology, 1998, Volume: 21, Issue:1

    Topics: Antineoplastic Agents; Busulfan; Humans; Hydroxyurea; Immunosuppressive Agents; Polycythemia Vera; R

1998
Is hydroxyurea leukemogenic in essential thrombocythemia?
    Blood, 1998, Aug-15, Volume: 92, Issue:4

    Topics: Acute Disease; Antineoplastic Agents, Alkylating; Bone Marrow; Busulfan; Chromosome Aberrations; Chr

1998
Leukemia and myelodysplasia in patients with essential thrombocythemia treated with cytotoxic agents.
    Haematologica, 1999, Volume: 84, Issue:11

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Busulfan; Female; Follow-Up Studies; Humans;

1999
Essential thrombocythemia in young adults: major thrombotic complications and complications during pregnancy--a follow-up study in 68 patients.
    Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis, 2000, Volume: 6, Issue:1

    Topics: Acute Disease; Adult; Age Factors; Arteriosclerosis; Aspirin; Busulfan; Cohort Studies; Disease-Free

2000
Leukemia and myelodysplasia effect of multiple cytotoxic therapy in essential thrombocythemia.
    Leukemia & lymphoma, 2000, Volume: 37, Issue:3-4

    Topics: Aged; Aged, 80 and over; Antibiotics, Antineoplastic; Busulfan; Fatal Outcome; Female; Humans; Hydro

2000
The predictive value of vascular risk factors and gender for the development of thrombotic complications in essential thrombocythemia.
    Annals of hematology, 2001, Volume: 80, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Arterial Occlusive Diseases; Blood Platelets; Busulfan; Female; Huma

2001
Second malignancies in patients with essential thrombocythaemia.
    British journal of haematology, 2002, Volume: 116, Issue:4

    Topics: Adult; Aged; Antineoplastic Agents; Busulfan; Female; Follow-Up Studies; Humans; Hydroxyurea; Male;

2002
Leukemic transformation with trisomy 8 in essential thrombocythemia: a report of four cases.
    European journal of haematology, 2002, Volume: 68, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Bone Marrow; Busulfan; Cell Transformation, Neoplastic; Chromosomes,

2002
Thrombocythaemia and multiple myeloma. A report on two cases.
    Acta medica Scandinavica, 1977, Volume: 201, Issue:3

    Topics: Aged; Blood Cell Count; Blood Platelets; Bone Marrow Cells; Busulfan; Female; Follow-Up Studies; Hum

1977
Microvascular occlusive lesions in primary thrombocythaemia.
    British journal of haematology, 1977, Volume: 36, Issue:4

    Topics: Adult; Aged; Busulfan; Capillaries; Diagnosis, Differential; Female; Gangrene; Humans; Ischemia; Mal

1977
[Case of megakaryocyte leukemia with an unusual course].
    Polskie Archiwum Medycyny Wewnetrznej, 1978, Volume: 60, Issue:4

    Topics: Adult; Busulfan; Female; Humans; Liver; Remission, Spontaneous; Thrombocythemia, Essential

1978
Priapsim caused by primary thrombocythemia.
    The Journal of urology, 1979, Volume: 121, Issue:2

    Topics: Adult; Blood Cell Count; Bone Marrow; Busulfan; Humans; Male; Plateletpheresis; Priapism; Thrombocyt

1979
[Essential thrombocytosis. Presentation of one case (author's transl)].
    Sangre, 1975, Volume: 20, Issue:1

    Topics: Adult; Aspirin; Busulfan; Humans; Male; Thrombocythemia, Essential

1975
Thrombocythemia and coronary artery disease.
    American heart journal, 1991, Volume: 122, Issue:2

    Topics: Adult; Aged; Aspirin; Busulfan; Coronary Disease; Female; Humans; Male; Middle Aged; Polycythemia Ve

1991
Incidence and risk factors for thrombotic complications in a historical cohort of 100 patients with essential thrombocythemia.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1990, Volume: 8, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Busulfan; Cohort Studies; Female; Follow-Up Studies; Hem

1990
Slowly progressive ischemic stroke as first manifestation of essential thrombocythemia.
    Stroke, 1989, Volume: 20, Issue:9

    Topics: Adult; Arterial Occlusive Diseases; Brain Ischemia; Busulfan; Cerebral Arterial Diseases; Humans; Ma

1989
8;21 translocation in myelodysplasia secondary to essential thrombocythemia.
    American journal of hematology, 1989, Volume: 30, Issue:4

    Topics: Aged; Busulfan; Cell Transformation, Neoplastic; Cytogenetics; Female; Humans; Karyotyping; Leukemia

1989
Essential thrombocythemia and leukemic transformation.
    Medicine, 1986, Volume: 65, Issue:6

    Topics: Adult; Aged; Bone Marrow; Busulfan; Cell Transformation, Neoplastic; Humans; Leukemia, Myeloid; Leuk

1986
[Clinical case. Primary thrombocythemia].
    Giornale di clinica medica, 1987, Volume: 68, Issue:2

    Topics: Adult; Busulfan; Diagnosis, Differential; Female; Humans; Mitobronitol; Thrombocythemia, Essential

1987
[Essential thrombocythemia].
    Harefuah, 1987, Mar-15, Volume: 112, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Bone Marrow; Busulfan; Humans; Middle Aged; Platelet Aggregation; Pr

1987
Primary thrombocythaemia treated with busulphan.
    British journal of haematology, 1986, Volume: 62, Issue:2

    Topics: Adult; Aged; Blood Cell Count; Bone Marrow; Busulfan; Female; Humans; Male; Middle Aged; Philadelphi

1986
Platelet dysfunction in essential thrombocythaemia.
    Annals of clinical research, 1974, Volume: 6, Issue:4

    Topics: Adenosine Diphosphate; Aged; Blood Cell Count; Blood Coagulation; Blood Platelets; Busulfan; Collage

1974
Primary thrombocythemia.
    Geriatrics, 1973, Volume: 28, Issue:1

    Topics: Adult; Aged; Blood Coagulation Tests; Bone Marrow Examination; Busulfan; Follow-Up Studies; Gastroin

1973
Thrombocytosis. A source of increased bleeding tendency.
    Acta chirurgica Scandinavica, 1973, Volume: 139, Issue:3

    Topics: Aged; Blood Cell Count; Blood Platelets; Busulfan; Carcinoma; Colon, Sigmoid; Colonic Neoplasms; Div

1973
Metabolism of human prothrombin and fibrinogen in patients with thrombocytosis secondary to myeloproliferative states.
    Blood, 1973, Volume: 42, Issue:1

    Topics: Adolescent; Adult; Aged; Alkaline Phosphatase; Blood Cell Count; Blood Coagulation Factors; Blood Co

1973
A study of 51 Cr-labelled platelets and the chromosomal pattern in a case of primary haemorrhagic thrombocythaemia.
    Acta haematologica, 1971, Volume: 46, Issue:3

    Topics: Aged; Blood Platelets; Blood Transfusion; Bone Marrow Cells; Busulfan; Cell Survival; Chromium Isoto

1971
Busulfan in early pregnancy.
    Obstetrics and gynecology, 1966, Volume: 27, Issue:5

    Topics: Adult; Busulfan; Female; Humans; Leukemia, Myeloid; Pregnancy; Pregnancy Complications, Hematologic;

1966
Studies on the phagocytic activity of neutrophilic leukocytes.
    Scandinavian journal of haematology. Supplementum, 1967, Volume: 2

    Topics: Adult; Age Factors; Aged; Alkaline Phosphatase; Anemia, Macrocytic; Animals; Biopsy; Bone Marrow Dis

1967
[Primary hemorrhagic thrombocythemia. 3 cases].
    Sangre, 1971, Volume: 16, Issue:3

    Topics: Aged; Anemia, Aplastic; Bone Marrow Examination; Busulfan; Female; Humans; Leukemia, Myeloid; Male;

1971
Disseminated scotochromogen infection and unusual myeloproliferative disorder. Report of a case and review of the literature.
    Annals of internal medicine, 1971, Volume: 75, Issue:5

    Topics: Adolescent; Adult; Aged; Autopsy; Busulfan; Child; Child, Preschool; Chlorambucil; Female; Humans; L

1971
Primary or hemorrhagic thrombocythemia.
    Archives of internal medicine, 1968, Volume: 122, Issue:1

    Topics: Adult; Anemia, Hypochromic; Busulfan; Female; Gastrointestinal Hemorrhage; Humans; Leukocytosis; Mal

1968
The dangers of surgery in uncontrolled haemorrhagic thrombocythaemia.
    The Medical journal of Australia, 1970, Apr-04, Volume: 1, Issue:14

    Topics: Aged; Blood Cell Count; Blood Platelets; Busulfan; Hemorrhage; Humans; Male; Middle Aged; Peptic Ulc

1970
The management of platelet disorders.
    Proceedings of the Royal Society of Medicine, 1968, Volume: 61, Issue:6

    Topics: Blood Platelets; Blood Transfusion; Busulfan; Glucocorticoids; Humans; Immunosuppressive Agents; Pho

1968
[Some questions on the problem of thrombocythemia].
    Problemy gematologii i perelivaniia krovi, 1968, Volume: 13, Issue:11

    Topics: Busulfan; Female; Gold Isotopes; Humans; Male; Phosphorus Isotopes; Radionuclide Imaging; Thrombocyt

1968
The treatment of Polycythemia vera and thrombocythemia with myleran (busulphan).
    Israel journal of medical sciences, 1965, Volume: 1, Issue:4

    Topics: Aged; Anemia; Busulfan; Female; Humans; Male; Phosphorus Isotopes; Polycythemia Vera; Thrombocythemi

1965